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This study examines the general trend of sustainable development for modern businesses, focusing on the four development strategies adopted by Huawei during the epidemic: digital inclusion, security and trustworthiness, greenness, and harmonious ecology. This study explores the risk to corporate sustainability and how supply chain risks can be effectively managed. Through a case study of Huawei’s three-year sustainability report and related data, it offers practical advice that will be valuable to other companies. The study calls on companies to develop sustainable supply chains while paying attention to social responsibility, incorporating environmental protection concepts, actively adopting digital communication technologies to cope with unknown risks, and enhancing their image to achieve long-term stable development. In the face of increasing global carbon emissions and sustainable development challenges, enterprises should strengthen their risk response capabilities, comprehensively consider the impacts of their supply chains, and practice the concept of sustainable development.

Objectives: The aim of this study was to investigate the effect of Panicum miliaceum involved in the repair of femur bone fracture in rats. Materials and Methods: In this study, 40 Wistar rats in five groups were studied as healthy, rats with lesion induced by surgery in femur (FX), FX rats treated with P. miliaceum extract (FX +100 and 200 P. miliaceum) and FX rats treated with Osteocare syrup (FX + OC). After 40 days, the serum levels of blood calcium (Ca), phosphorus (P), and alkaline phosphatase (ALP) along with activity of glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) enzymes, and nitric oxide (NO) level were measured. The serum level of cytokines (IL-6, C-reactive protein [CRP], IL-10, IL-1β, and tumor necrosis factor-α [TNF-α]) was also measured by ELISA. The expression of OPG, RANK, RANKL, and BMP-2 genes and proteins were evaluated by real-time PCR and Western blotting techniques, respectively. Results: The results showed that P. miliaceum was able to decrease the activity of ALP enzyme in addition to increasing serum Ca and P levels and GPx, SOD, and CAT activity. P. miliaceum reduces serum IL-6, IL-1β, and TNF-α, and NO levels. Also, the extract of this plant could increase the expression of OPG/RANK/BMP-2 pathway genes and proteins. Conclusion: P. miliaceum can be used as a prodrug in traditional medicine to repair bone fractures and osteoporosis. [ABSTRACT FROM AUTHOR]