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197 results on '"Pandurangi, Anand K."'

13. YinYang dynamic neurobiological modeling and diagnostic analysis of major depressive and bipolar disorders

Author

Zhang, Wen-Ran, Pandurangi, Anand K., and Peace, Karl E.

Subjects
Affective disorders -- Diagnosis, Affective disorders -- Care and treatment, Therapeutics -- Models, Homeopathy -- Materia medica and therapeutics, Homeopathy -- Models, Biological sciences, Business, Computers, Health care industry
Abstract

Since millions suffer from major depressive and bipolar disorders, the modeling, characterization, classification, and diagnostic analysis of such mental disorders bear great significance in medical and pharmaceutical research. YinYang bipolar sets are introduced for neurobiological modeling and diagnostic analysis of such disorders. It is shown that bipolar sets and a bipolar dynamic modus ponens (BDMP) build a technological bridge from a linear, static, and closed world to a nonlinear, dynamic, and open world of equilibria, quasi-equilibria, or nonequilibria and provide a novel model for bipolar neurobiological diagnostic analysis with added rigor to the current standard. It is shown that bipolar inference can help in understanding both the classic manifestations and the counterintuitive symptoms of bipolar disorders with applications in clinical psychopharmacology. Mathematical and visual characterizations of core features of such disorders arc presented. A unified diagnosis and outcome model of different treatments are presented for different types of bipolar disorders. The significance and novelty of this work is twofold: 1) it introduces YinYang into biomedicine for the understanding of certain neurobiological disorders and fosters a new standard model for clinical, therapeutic, and pharmacological research and applications; 2) it presents a mathematical basis for the characterization of mood regulation in individuals and/or a cohort of patients with applications in biomedical engineering and potential applications in nanotechnologies for integrated care of major depressive and bipolar disorders. Index Terms--Bipolar diagnostic analysis, bipolar neurobiological modeling, clinical psychopharmacology, mental depression and bipolar disorder, YinYang bipolar sets.

Published
2007

17. Psychotropic drug considerations in depressed patients with metabolic disturbances

Author

Vieweg, W. Victor R., Levy, James R., Fredrickson, Sonja K., Chipkin, Stuart R., Beatty-Brooks, Mary, Fernandez, Antony, Hasnain, Mehrul, and Pandurangi, Anand K.

Subjects
Body weight -- Management, Psychotropic drugs -- Physiological aspects, Psychotropic drugs -- Research, Depression, Mental -- Drug therapy, Metabolic diseases -- Care and treatment, Company business management, Health, Health care industry
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjmed.2007.08.043 Byline: W. Victor R. Vieweg (a)(b)(d)(e), James R. Levy (b)(e), Sonja K. Fredrickson (b)(e), Stuart R. Chipkin (f), Mary Beatty-Brooks (c), Antony Fernandez (a)(d), Mehrul Hasnain (g), Anand K. Pandurangi (d) Keywords: Depression; Diabetes mellitus; Metabolic syndrome; Obesity; Psychotropic drugs Abstract: Depression, obesity, diabetes mellitus, and the metabolic syndrome are conditions commonly treated in primary care. The prevalence of each condition separately does not explain the frequency of their co-occurrence. Depression may lead to or exacerbate these endocrine and metabolic conditions. Conversely, these medical conditions may lead to or exacerbate depression. Psychotropic drugs that treat depression may increase appetite with resultant weight gain. Rarely, such agents may be associated with weight loss. We review the potential for psychotropic drugs to alter body weight and provide a table as a guide to drug selection. Unless circumstances dictate otherwise, clinicians should select psychotropic drugs least likely to induce weight gain when treating depressed patients with obesity, diabetes mellitus, or the metabolic syndrome. Even drugs generally thought to be 'weight neutral' may occasionally be associated with weight gain. Thus, alerting patients to this potential and due diligence form the cornerstone of weight management in the depressed patient. Author Affiliation: (a) Psychiatry Service, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Va (b) Medicine Service, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Va (c) Medical Media, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Va (d) Department of Psychiatry, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond (e) Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond (f) School of Public Health and Health Sciences, University of Massachusetts, Amherst (g) Department of Psychiatry, Western Regional Integrated Health Authority, Sir Thomas Roddick Hospital, Stephenville, Newfoundland, Canada.

Published
2008

18. The risk of overweight in children and adolescents with major mental illness

Author

Hasnain, Mehrul, Vieweg, W. Victor R., Hettema, John M., Colton, David, Fernandez, Antony, and Pandurangi, Anand K.

Subjects
Obesity in children -- Risk factors, Child psychopathology -- Research, Psychotropic drugs -- Complications and side effects, Psychotropic drugs -- Research, Body mass index -- Analysis, Health
Published
2008

21. Correlation between high risk obesity groups and low socioeconomic status in school children

Author

Vieweg, Victor R., Johnston, Christopher H., Lanier, Jack O., Fernandez, Antony, and Pandurangi, Anand K.

Subjects
Obesity -- Risk factors -- Health aspects -- Research, High school students -- Health aspects -- Social aspects -- Research, Elementary school students -- Health aspects -- Social aspects -- Research, Body mass index -- Research -- Health aspects -- Social aspects, Social classes -- Health aspects -- Social aspects -- Research, Health
Abstract

Objective: Obesity is a major health problem among children and adolescents which is potentially affected by socioeconomic status (SES). The high risk group (HRG) comprises those youths with a body [...]

Published
2007

22. Diversity in schizophrenia: toward a richer biopsychososocial understanding for social work practice

Author

Farmer, Rosemary L. and Pandurangi, Anand K.

Subjects
Social service -- Research -- Psychological aspects, Schizophrenia -- Research, Schizophrenics -- Psychological aspects -- Research, Health, Sociology and social work, Psychological aspects, Research
Abstract

By incorporating information from the neurosciences, the study discussed in this article supports the view that schizophrenia is a diverse and biopsychosocial phenomenon. Forty-two people with schizophrenia were placed in one of two groups: people with a larger ventricle-to-brain ratio (VBR) or cortical atrophy (CA) or both and people without these conditions. The authors hypothesized that the former would have lower levels of psychosocial adaptation, higher levels of stress, and lower levels of self-esteem and would have a different course of illness than people without these two conditions. The study found few differences between the two groups, but there were significant differences between women and men and between African American and white participants. Implications for social work practice in the area of serious mental illness are discussed. Key words cortical atrophy, course of illness, psychosocial adaptation, schizophrenia, ventricle-to-brain ratio, The social work profession has long described its conceptual base as biopsychosocial. Yet the profession has focused primarily on the psychological and social aspects of human behavior, relegating the biological [...]

Published
1997

23. Invited comment

Author

Vieweg, W. Victor R. and Pandurangi, Anand K.

Published
2005

24. Posttraumatic Stress Disorder: Clinical Features, Pathophysiology, and Treatment

Author

Vieweg, W. Victor R., Julius, Demetrios A., Fernandez, Antony, Beatty-Brooks, Mary, Hettema, John M., and Pandurangi, Anand K.

Subjects
Post-traumatic stress disorder -- Risk factors, Post-traumatic stress disorder -- Care and treatment, Post-traumatic stress disorder -- Research, Health, Health care industry
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjmed.2005.09.027 Byline: W. Victor R. Vieweg (a)(b)(d)(e), Demetrios A. Julius (a)(d), Antony Fernandez (a)(d), Mary Beatty-Brooks (c), John M. Hettema (d), Anand K. Pandurangi (d) Keywords: Anxiety disorder; Depression; Military veterans; Posttraumatic stress disorder (PTSD); Primary care; Rape victims Abstract: Posttraumatic stress disorder (PSTD), classified as an anxiety disorder, has become increasingly important because of wars overseas, natural disasters, and domestic violence. After trauma exposes the victim to actual or threatened death or serious injury, 3 dimensions of PTSD unfold: (1) reexperiencing the event with distressing recollections, dreams, flashbacks, and/or psychologic and physical distress; (2) persistent avoidance of stimuli that might invite memories or experiences of the trauma; and (3) increased arousal. Traumatic events sufficient to produce PTSD in susceptible subjects may reach a lifetime prevalence of 50% to 90%. The actual lifetime prevalence of PTSD among US citizens is approximately 8%, with the clinical course driven by pathophysiologic changes in the amygdala and hippocampus. Comorbid depression and other anxiety disorders are common. General principles of treatment include the immediate management of PTSD symptoms and signs; management of any trauma-related comorbid conditions; nonpharmacologic interventions including cognitive behavioral treatment; and psychopharmacologic agents including antidepressants (selective serotonin reuptake inhibitors most commonly), antianxiety medications, mood stabilizing drugs, and antipsychotics. This review of PTSD will provide the reader with a clearer understanding of this condition, an increased capacity to recognize and treat this syndrome, and a greater appreciation for the role of the internist in PTSD. Author Affiliation: (a) Psychiatry, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Va (b) Medicine Services, Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Va (c) Medical Media, Hunter Holmes McGuire Veterans Affairs Medical Center,Richmond, Va (d) Department of Psychiatry, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Va (e) Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Va Article History: Received 5 April 2005

Published
2006

26. The neglect of culture in psychiatric nosology: the case of culture bound syndromes

Author

Aderibigbe, Yekeen A. and Pandurangi, Anand K.

Subjects
Nosology -- Research, Culture -- Psychological aspects, Syndromes -- Research, Mental illness -- Diagnosis, Psychology and mental health, Sociology and social work
Abstract

Descriptive psychopathology and clinical phenomenology inform contemporary psychiatric diagnosis and nosology. The process of psychiatric diagnosis and classification is intricate and subject to continuous revision. This paper attempts to illustrate the effect of culture on psychopathology, with special emphasis on the diagnosis and classification of culture bound syndromes. There is a need for more clarity and specificity about the diagnosis and classification of culture bound syndromes. The paper suggests some questions that need to be addressed for the better integration of these syndromes into the main body of international classificatory systems. It is presumed that answers to these questions will provide a better nosological framework for culture bound syndromes.

Published
1995

28. Toxicology Findings in Child and Adolescent Suicides in Virginia: 1987–2003

Author

Vieweg, W. Victor R., Pandurangi, Anand K., Anum, Emmanuel A., Lanier, Jack O., Fierro, Marcella F., and Fernandez, Antony

Subjects
Original Articles, geographic locations, health care economics and organizations
Abstract

In a follow-up report of child and adolescent suicides in Virginia, we describe postmortem toxicology findings in a subset of these youths.We analyzed "unnatural" deaths from Virginia's Office of the Chief Medical Examiner for 1987 to 2003. There were 2818 unnatural deaths in children and adolescents. We grouped unnatural deaths as accidents, homicides, and suicides. Toxicology records were available for 753 cases, of which 732 were black or white youths.There were no age differences among suicide victims and accident or homicide victims. Whites were more likely than blacks to die by accident and suicide. White females were more likely than black females to commit suicide. Black males were more likely than white males to suffer homicide. For all unexpected deaths, antidepressants were more commonly found among whites than blacks. Suicide by poisoning occurred more commonly among whites. Recreational drugs were more commonly found among blacks than whites. Suicide by gun occurred more commonly among blacks. Antidepressants were found in 39 black and white suicide victims. Anti-depressants (all tricyclic antidepressants) were causally related in 17 cases of suicide by poisoning. No other antidepressants were found in lethal levels in suicide by poisoning. Selective serotonin reuptake inhibitors (SSRIs)/venlafaxine appeared more commonly in the suicides (p.0001) than in accidents or homicides. For suicides, SSRIs appeared no more commonly in poisoning than in gun or hanging deaths (p = .695).Antidepressants appeared more commonly among youths committing suicide than those dying by accident or homicide. SSRIs did not appear more commonly among youths committing suicide by poisoning than those committing suicide by gun or hanging. Because our data are descriptive, they are subject to over-interpretation. Cause-effect inferences should not be drawn.

Published
2006

49. NMS and HIV

Author

Pelonero, Anthony L., primary, Levenson, James L., additional, and Pandurangi, Anand K., additional

Published
1999
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