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7. [Effects of mitomycin C on the expression and transport of ice-nuclei proteins of Erwinia herbicola].

Author

Chen QS, Gao XZ, Yan YL, Song LP, Pang GC, and Guo SH

Subjects
Culture Media pharmacology, Erwinia drug effects, Erwinia ultrastructure, Freezing, Microscopy, Electron, Protein Transport drug effects, SOS Response, Genetics, Temperature, Bacterial Outer Membrane Proteins metabolism, Erwinia metabolism, Mitomycin pharmacology
Abstract

Abstract: In this paper, Mitomycin C (MMC) was added to different kinds of medium to study the effects of different cultural conditions on the Erwinia herbicola 10025A. For the first time it was confirmed that the expressed activity of the ice-nuclei active protein was different from its transportable manner from the ice nucleation active bacteria (Erwinia herbicola 10025A). The findings indicated that MMC could stimulate the SOS response,and induce the synthesis of some enzymes and proteins, which take part in repairing the damaged DNA. The effects of the MMC on the E. herbicola under different media were different. It could increase the ice nucleation activity of the E. herbicola, forming new small vesicles, which are secreted to the outside of membrane. The importance of this research for study the living mechanism of cells ander poor condition was discussed.

Published
2005

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