36 results on '"Pannifer, Andrew"'
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2. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
3. IMI European Lead Factory — democratizing access to high-throughput screening
4. In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer’s Disease
5. Structural studies on protein tyrosine phosphatases
6. The ELF Honest Data Broker: informatics enabling public–private collaboration in a precompetitive arena
7. The Joint European Compound Library: boosting precompetitive research
8. IMI European Lead Factory — democratizing access to high-throughput screening
9. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
10. Crystal structure of the anthrax lethal factor
11. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents
12. Synthesis and Structure‐Activity Relationships of N ‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6
13. Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1
14. Abstract LB-B17: Characterization of small molecule inhibitors of the Nrf2-Keap1 interaction using MicroScale Thermophoresis
15. [P1-077]: THE IDENTIFICATION AND CHARACTERISATION OF SMALL-MOLECULE HUMAN ABAD INHIBITORS AS THERAPEUTICS IN ALZHEIMER's DISEASE
16. Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6.
17. Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR
18. Abstract A113: A fragment-based approach towards the identification of small molecule inhibitors of fascin 1
19. The importance of triaging in determining the quality of output from high-throughput screening
20. Fragment based discovery of a novel and selective PI3 kinase inhibitor
21. THE IDENTIFICATION AND CHARACTERISATION OF SMALL-MOLECULE HUMAN ABAD INHIBITORS AS THERAPEUTICS IN ALZHEIMER’S DISEASE
22. A novel small-molecule MRCK inhibitor blocks cancer cell invasion
23. Analysis of the human cofilin 1 structure reveals conformational changes required for actin binding
24. Structural Insights into a Unique Inhibitor Binding Pocket in Kinesin Spindle Protein
25. Corrigendum to “Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR” [Bioorg. Med. Chem. Lett. 22 (2012) 5098–5103]
26. Using Fragment-Based Technologies to Target Protein-Protein Interactions
27. Design and Structure of Stapled Peptides Binding to Estrogen Receptors
28. Abstract 5779: The discovery of the potent and selective PI3K/mTOR dual inhibitor PF-04691502 through structure-based drug design
29. Novel thienopyrrole glycogen phosphorylase inhibitors: Synthesis, in vitro SAR and crystallographic studies
30. SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors
31. Structure-based design of protein tyrosine phosphatase-1B inhibitors
32. Imidazo[1,2- b ]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors
33. Visualization of the Cysteinyl-phosphate Intermediate of a Protein-tyrosine Phosphatase by X-ray Crystallography
34. Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors
35. Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.
36. Using fragment-based technologies to target protein-protein interactions.
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