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934 results on '"Panza, Julio A."'

5. Optimal medical therapy with or without surgical revascularization and long-term outcomes in ischemic cardiomyopathy

Author

Dabrowski, Rafal, Djokovic, Ljubomir, Drazner, Mark, Haddad, Haissam, Ali, Imtiaz S., Keltai, Matyas, Naik, Ajay, Sopko, George, Golba, Krzysztof, Andersson, Bert, Carson, Peter, Kukulski, Tomasz, Farsky, Pedro S., White, Jennifer, Al-Khalidi, Hussein R., Sueta, Carla A., Rouleau, Jean L., Panza, Julio A., Velazquez, Eric J., and O'Connor, Christopher M.

Published
2022
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11. Global burden of cardiovascular disease attributable to smoking, 1990–2019: an analysis of the 2019 Global Burden of Disease Study

Author

Khan Minhas, Abdul Mannan, Sedhom, Ramy, Jean, Estelle D, Shapiro, Michael D, Panza, Julio A, Alam, Mahboob, Virani, Salim S, Ballantyne, Christie M, and Abramov, Dmitry

Abstract

The burden of cardiovascular disease (CVD) attributed to smoking declined worldwide between 1990 and 2019. The burden of smoking-attributed CVD was higher in men than in women in 2019. There were significant variations between different countries and regions such that Eastern Europe had the highest death rate and Andean Latin America had the lowest death rate in 2019. Also, countries with high socio-economic status had lower death rates from smoking-attributed CVD. This highlights the need for targeted interventions to reduce the burden of smoking-attributed CVD.The overall age-adjusted deaths from CVD attributed to smoking declined from 57.16/100 000 in 1990 to 33.03/100 000 in 2019.In 2019, ischaemic heart disease was the leading cause of smoking-attributed CVD deaths.

Published
2024
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17. Trends in the Burden of Adult Congenital Heart Disease in US Emergency Departments

Author

Agarwal, Shikhar, Sud, Karan, Khera, Sahil, Kolte, Dhaval, Fonarow, Gregg C, Panza, Julio A, and Menon, Venu

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Emergency Care, Clinical Research, Health Services, Heart Disease, Prevention, Cardiovascular, Health and social care services research, 8.1 Organisation and delivery of services, Good Health and Well Being, Adult, Cost of Illness, Emergency Service, Hospital, Female, Heart Defects, Congenital, Hospital Mortality, Humans, Incidence, Male, Prevalence, Retrospective Studies, Survival Rate, United States, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundWe assessed trends in incidence, in-hospital mortality, and admission among patients with adult congenital heart disease (ACHD) presenting to the emergency department (ED) from 2006 to 2012.HypothesisThere is a considerable burden of ACHD in the US EDs.MethodsWe used the 2006-2012 US Nationwide Emergency Department Sample. All ED visits with ACHD were identified using standard International Classification of Diseases, Ninth Edition, Clinical Modification codes.ResultsThe number of patients presenting to the ED with simple (40.6%) as well as complex (37.6%) ACHD across 2006-2012 increased significantly. Also, there was a considerable increase in prevalence of traditional cardiovascular risk factors among ACHD patients, including hypertension, diabetes, smoking, obesity, and chronic kidney disease. Besides miscellaneous noncardiovascular conditions, nonspecific chest pain (15.9%) and respiratory disorders (15.0%) were the most common reasons for ED visits among patients with simple and complex ACHD, respectively. Although there was a trend toward decrease in admissions across 2006-2012 (Ptrend

Published
2016

18. Smoker's Paradox in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

Author

Gupta, Tanush, Kolte, Dhaval, Khera, Sahil, Harikrishnan, Prakash, Mujib, Marjan, Aronow, Wilbert S, Jain, Diwakar, Ahmed, Ali, Cooper, Howard A, Frishman, William H, Bhatt, Deepak L, Fonarow, Gregg C, and Panza, Julio A

Subjects
Humans, Postoperative Complications, Treatment Outcome, Incidence, Hospital Mortality, Odds Ratio, Risk Assessment, Risk Factors, Retrospective Studies, Follow-Up Studies, Smoking, Middle Aged, United States, Female, Male, Percutaneous Coronary Intervention, ST Elevation Myocardial Infarction, ST‐segment elevation myocardial infarction, primary percutaneous coronary intervention, smoker's paradox, smoking, ST-segment elevation myocardial infarction, Clinical Research, Cardiovascular, Prevention, Heart Disease, Heart Disease - Coronary Heart Disease, Cardiorespiratory Medicine and Haematology
Abstract

BackgroundPrior studies have found that smokers undergoing thrombolytic therapy for ST-segment elevation myocardial infarction have lower in-hospital mortality than nonsmokers, a phenomenon called the "smoker's paradox." Evidence, however, has been conflicting regarding whether this paradoxical association persists in the era of primary percutaneous coronary intervention.Methods and resultsWe used the 2003-2012 National Inpatient Sample databases to identify all patients aged ≥18 years who underwent primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Multivariable logistic regression was used to compare in-hospital mortality between smokers (current and former) and nonsmokers. Of the 985 174 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention, 438 954 (44.6%) were smokers. Smokers were younger, were more often men, and were less likely to have traditional vascular risk factors than nonsmokers. Smokers had lower observed in-hospital mortality compared with nonsmokers (2.0% versus 5.9%; unadjusted odds ratio 0.32, 95% CI 0.31-0.33, P

Published
2016

20. Association of chronic renal insufficiency with in-hospital outcomes after percutaneous coronary intervention.

Author

Gupta, Tanush, Paul, Neha, Kolte, Dhaval, Harikrishnan, Prakash, Khera, Sahil, Aronow, Wilbert S, Mujib, Marjan, Palaniswamy, Chandrasekar, Sule, Sachin, Jain, Diwakar, Ahmed, Ali, Cooper, Howard A, Frishman, William H, Bhatt, Deepak L, Fonarow, Gregg C, and Panza, Julio A

Subjects
Humans, Kidney Failure, Chronic, Myocardial Ischemia, Postoperative Hemorrhage, Treatment Outcome, Length of Stay, Hospital Mortality, Aged, Middle Aged, Hospital Costs, United States, Female, Male, Renal Insufficiency, Chronic, Acute Coronary Syndrome, Percutaneous Coronary Intervention, chronic kidney disease, end‐stage renal disease, in‐hospital mortality, percutaneous coronary intervention, postprocedure hemorrhage, end-stage renal disease, in-hospital mortality, Kidney Failure, Chronic, Renal Insufficiency, Cardiorespiratory Medicine and Haematology
Abstract

BackgroundThe association of chronic renal insufficiency with outcomes after percutaneous coronary intervention (PCI) in the current era of drug-eluting stents and modern antithrombotic therapy has not been well characterized.Methods and resultsWe queried the 2007-2011 Nationwide Inpatient Sample databases to identify all patients aged ≥18 years who underwent PCI. Multivariable logistic regression was used to compare in-hospital outcomes among patients with chronic kidney disease (CKD), patients with end-stage renal disease (ESRD), and those without CKD or ESRD. Of 3 187 404 patients who underwent PCI, 89% had no CKD/ESRD; 8.6% had CKD; and 2.4% had ESRD. Compared to patients with no CKD/ESRD, patients with CKD and patients with ESRD had higher in-hospital mortality (1.4% versus 2.7% versus 4.4%, respectively; adjusted odds ratio for CKD 1.15, 95% CI 1.12 to 1.19, P

Published
2015

21. Pretransplant Coagulopathy and In‐hospital Outcomes Among Heart Transplant Recipients: A Propensity‐Matched Nationwide Inpatient Sample Study

Author

Mujib, Marjan, Khanna, Neel, Mazumder, Nabila K, Aronow, Wilbert S, Kolte, Dhaval, Khera, Sahil, Palaniswamy, Chandrasekar, Jain, Diwakar, Lanier, Gregg M, Sule, Sachin, Ahmed, Ali, Levy, Wayne C, Prabhu, Sumanth D, Cooper, Howard A, Panza, Julio A, Gass, Alan L, and Fonarow, Gregg C

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cardiovascular, Clinical Research, Transplantation, Good Health and Well Being, Adult, Aged, Blood Coagulation Disorders, Female, Heart Transplantation, Hospital Charges, Hospital Mortality, Humans, Inpatients, Length of Stay, Male, Middle Aged, Propensity Score, Sampling Studies, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundThe prevalence and contemporary trends of pre-heart transplantation (HT) coagulopathy and associated clinical outcomes have not been studied from a national database.HypothesisPre-HT coagulopathy is associated with increased in-hospital mortality.MethodsAmong 2454 adult HT recipients from the 2003 to 2010 Nationwide Inpatient Sample databases, 707 (29%) had pre-HT coagulopathy (defined as a comorbidity variable, based on International Classification of Diseases, Ninthe Revision, Clinical Modification and Diagnosis Related Group codes). We used propensity scores for coagulopathy to assemble a matched cohort of 664 pairs of patients with and without coagulopathy balanced in 54 baseline characteristics.ResultsThe prevalence of pre-HT coagulopathy increased from 17% in 2003 to 44% in 2010 (P for trend

Published
2015

24. Non‐ST‐Elevation Myocardial Infarction in the United States: Contemporary Trends in Incidence, Utilization of the Early Invasive Strategy, and In‐Hospital Outcomes

Author

Khera, Sahil, Kolte, Dhaval, Aronow, Wilbert S, Palaniswamy, Chandrasekar, Subramanian, Kathir Selvan, Hashim, Taimoor, Mujib, Marjan, Jain, Diwakar, Paudel, Rajiv, Ahmed, Ali, Frishman, William H, Bhatt, Deepak L, Panza, Julio A, and Fonarow, Gregg C

Subjects
Heart Disease - Coronary Heart Disease, Cardiovascular, Heart Disease, Clinical Research, Health Services, Good Health and Well Being, Adult, Aged, Coronary Angiography, Coronary Artery Bypass, Early Medical Intervention, Ethnicity, Female, Hospital Mortality, Humans, Incidence, Logistic Models, Male, Middle Aged, Myocardial Infarction, Percutaneous Coronary Intervention, United States, early invasive strategy, in-hospital mortality, non-ST-elevation myocardial infarction, temporal trends, in‐hospital mortality, non‐ST‐elevation myocardial infarction, Cardiorespiratory Medicine and Haematology
Abstract

There has been a paradigm shift in the definition of timing of early invasive strategy (EIS) for patients admitted with non-ST-elevation myocardial infarction (NSTEMI) in the last decade. Data on trends of EIS for NSTEMI and associated in-hospital outcomes are limited. Our aim is to analyze temporal trends in the incidence, utilization of early invasive strategy, and in-hospital outcomes of NSTEMI in the United States. We analyzed the 2002-2011 Nationwide Inpatient Sample databases to identify all patients ≥40 years of age with the principal diagnosis of acute myocardial infarction (AMI) and NSTEMI. Logistic regression was used for overall, age-, sex-, and race/ethnicity-stratified trend analysis. From 2002 to 2011, we identified 6 512 372 patients with AMI. Of these, 3 981 119 (61.1%) had NSTEMI. The proportion of patients with NSTEMI increased from 52.8% in 2002 to 68.6% in 2011 (adjusted odds ratio [OR; per year], 1.055; 95% confidence interval [CI], 1.054 to 1.056) in the overall cohort. Similar trends were observed in age-, sex-, and race/ethnicity-stratified groups. From 2002 to 2011, utilization of EIS at day 0 increased from 14.9% to 21.8% (Ptrend

Published
2014

25. Temporal trends in incidence and outcomes of peripartum cardiomyopathy in the United States: a nationwide population-based study.

Author

Kolte, Dhaval, Khera, Sahil, Aronow, Wilbert S, Palaniswamy, Chandrasekar, Mujib, Marjan, Ahn, Chul, Jain, Diwakar, Gass, Alan, Ahmed, Ali, Panza, Julio A, and Fonarow, Gregg C

Subjects
Humans, Pregnancy Complications, Cardiovascular, Puerperal Disorders, Cardiomyopathy, Dilated, Pregnancy Outcome, Incidence, Maternal Mortality, Age Factors, Pregnancy, Adolescent, Adult, Middle Aged, Continental Population Groups, United States, Female, Young Adult, Peripartum Period, incidence, major adverse events, outcomes, peripartum cardiomyopathy, trends, Pregnancy Complications, Cardiovascular, Cardiomyopathy, Dilated, Cardiorespiratory Medicine and Haematology
Abstract

BackgroundThe reported incidence of peripartum cardiomyopathy (PPCM) in the United States varies widely. Furthermore, limited information is available on the temporal trends in incidence and outcomes of PPCM.Methods and resultsWe queried the 2004-2011 Nationwide Inpatient Sample databases to identify all women aged 15 to 54 years with the diagnosis of PPCM. Temporal trends in incidence (per 10 000 live births), maternal major adverse events (MAE; defined as in-hospital mortality, cardiac arrest, heart transplant, mechanical circulatory support, acute pulmonary edema, thromboembolism, or implantable cardioverter defibrillator/permanent pacemaker implantation), cardiogenic shock, and mean length of stay were analyzed. From 2004 to 2011, we identified 34 219 women aged 15 to 54 years with PPCM. The overall PPCM rate was 10.3 per 10 000 (or 1 in 968) live births. PPCM incidence increased from 8.5 to 11.8 per 10 000 live births (Ptrend

Published
2014

26. Updates on Prognostication of Takotsubo Cardiomyopathy: A Literature Review.

Author

Arya, Priyanka, Panza, Julio A., and Chhabra, Lovely

Subjects
ATRIAL arrhythmias, CHRONIC kidney failure, TAKOTSUBO cardiomyopathy, AGE distribution, LEFT ventricular dysfunction, RACE, DIABETES, ACE inhibitors, SEX distribution, RISK assessment, SEPSIS, ADRENERGIC beta blockers, CARDIOGENIC shock, VENTRICULAR outflow obstruction, OBSTRUCTIVE lung diseases, ANEMIA, ALDOSTERONE antagonists, BODY mass index, COMORBIDITY, DISEASE risk factors, SYMPTOMS, DISEASE complications
Abstract

Takotsubo cardiomyopathy (TTC), commonly known as "broken heart syndrome" or "stress cardiomyopathy," is characterized by transient left ventricular (LV) systolic dysfunction, usually in the absence of significant obstructive coronary artery stenosis. The pathophysiology of TTC remains elusive; however, the three most common plausible mechanisms include catecholamine surge causing myocardial stunning, multivessel coronary spasm, and microvascular dysfunction. Although initially thought to be a benign, reversible, and transient disorder, newer research data demonstrate that TTC may sometimes have severe short-term complications and some long-term residual effects. Several risk factors have been associated with the outcomes of TTC. In this review, we aim to provide a comprehensive review of the prognostication of TTC in the context of different clinical variables presented in multiple research studies. Various clinical factors, including the types of TTC triggers, the patient's sex, the presence of cardiogenic shock, atrial arrhythmias, LV tract obstruction, and the presence of certain other clinical comorbidities may significantly impact patient outcomes in TTC patients. A thorough understanding of these factors helps clinicians to better prognosticate the outcome of their patients. Furthermore, early institution of aggressive treatment interventions in the presence of these risk factors may improve the subsequent clinical course. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Regional Variation in Utilization, In-hospital Mortality, and Health-Care Resource Use of Transcatheter Aortic Valve Implantation in the United States

Author

Gupta, Tanush, Kalra, Ankur, Kolte, Dhaval, Khera, Sahil, Villablanca, Pedro A., Goel, Kashish, Bortnick, Anna E., Aronow, Wilbert S., Panza, Julio A., Kleiman, Neal S., Abbott, J. Dawn, Slovut, David P., Taub, Cynthia C., Fonarow, Gregg C., Reardon, Michael J., Rihal, Charanjit S., Garcia, Mario J., and Bhatt, Deepak L.

Published
2017
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41. Implication of right ventricular dysfunction on long-term outcome in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting with or without surgical ventricular reconstruction

Author

Kukulski, Tomasz, She, Lilin, Racine, Normand, Gradinac, Sinisa, Panza, Julio A., Velazquez, Eric J., Chan, Kwan, Petrie, Mark C., Lee, Kerry L., Pellikka, Patricia A., Romanov, Alexander, Biernat, Jolanta, Rouleau, Jean L., Batlle, Carmen, Rogowski, Jan, Ferrazzi, Paolo, Zembala, Marian, and Oh, Jae K.

Published
2015
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42. Trends in Management and Outcomes of ST-Elevation Myocardial Infarction in Patients With End-Stage Renal Disease in the United States

Author

Gupta, Tanush, Harikrishnan, Prakash, Kolte, Dhaval, Khera, Sahil, Subramanian, Kathir S., Mujib, Marjan, Masud, Ali, Palaniswamy, Chandrasekar, Sule, Sachin, Jain, Diwakar, Ahmed, Ali, Lanier, Gregg M., Cooper, Howard A., Frishman, William H., Bhatt, Deepak L., Fonarow, Gregg C., Panza, Julio A., and Aronow, Wilbert S.

Published
2015
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43. Pharmacotherapies in Heart Failure With Preserved Ejection Fraction

Author

Sreenivasan, Jayakumar, primary, Malik, Aaqib, additional, Khan, Muhammad Shahzeb, additional, Lloji, Amanda, additional, Hooda, Urvashi, additional, Aronow, Wilbert S., additional, Lanier, Gregg M., additional, Pan, Stephen, additional, Greene, Stephen J., additional, Murad, M. Hassan, additional, Michos, Erin D., additional, Cooper, Howard A., additional, Gass, Alan, additional, Gupta, Rahul, additional, Desai, Nihar R., additional, Mentz, Robert J., additional, Frishman, William H., additional, and Panza, Julio A., additional

Published
2022
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44. Optimal medical therapy with or without surgical revascularization and long-term outcomes in ischemic cardiomyopathy

Author

Farsky, Pedro S., primary, White, Jennifer, additional, Al-Khalidi, Hussein R., additional, Sueta, Carla A., additional, Rouleau, Jean L., additional, Panza, Julio A., additional, Velazquez, Eric J., additional, O'Connor, Christopher M., additional, Dabrowski, Rafal, additional, Djokovic, Ljubomir, additional, Drazner, Mark, additional, Haddad, Haissam, additional, Ali, Imtiaz S., additional, Keltai, Matyas, additional, Naik, Ajay, additional, Sopko, George, additional, Golba, Krzysztof, additional, Andersson, Bert, additional, Carson, Peter, additional, and Kukulski, Tomasz, additional

Published
2022
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45. Ecpella 5.5

Author

Levine, Avi, primary, Kai, Masashi, additional, Ohira, Suguru, additional, Panza, Julio A., additional, Pan, Stephen, additional, Lanier, Gregg, additional, Aggarwal-Gupta, Chhaya, additional, and Gass, Alan, additional

Published
2022
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50. Contemporary Sex-Based Differences by Age in Presenting Characteristics, Use of an Early Invasive Strategy, and Inhospital Mortality in Patients With Non–ST-Segment–Elevation Myocardial Infarction in the United States

Author

Gupta, Tanush, Kolte, Dhaval, Khera, Sahil, Agarwal, Nayan, Villablanca, Pedro A., Goel, Kashish, Patel, Kavisha, Aronow, Wilbert S., Wiley, Jose, Bortnick, Anna E., Aronow, Herbert D., Abbott, J. Dawn, Pyo, Robert T., Panza, Julio A., Menegus, Mark A., Rihal, Charanjit S., Fonarow, Gregg C., Garcia, Mario J., and Bhatt, Deepak L.

Published
2018
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