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575 results on '"Pappot, Helle"'

1. Using Biometric Sensor Data to Monitor Cancer Patients During Radiotherapy: Protocol for the OncoWatch Feasibility Study

Author

Holländer-Mieritz, Cecilie, Vogelius, Ivan R, Kristensen, Claus A, Green, Allan, Rindum, Judith L, and Pappot, Helle

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundPatients with head and neck cancer (HNC) experience severe side effects during radiotherapy (RT). Ongoing technological advances in wearable biometric sensors allow for the collection of objective data (eg, physical activity and heart rate), which might, in the future, help detect and counter side effects before they become severe. A smartwatch such as the Apple Watch allows for objective data monitoring outside the hospital with minimal effort from the patient. To determine whether such tools can be implemented in the oncological setting, feasibility studies are needed. ObjectiveThis protocol describes the design of the OncoWatch 1.0 feasibility study that assesses the adherence of patients with HNC to an Apple Watch during RT. MethodsA prospective, single-cohort trial will be conducted at the Department of Oncology, Rigshospitalet (Copenhagen, Denmark). Patients aged ≥18 years intended for primary or postoperative curatively intended RT for HNC will be recruited. Consenting patients will be asked to wear an Apple Watch on the wrist during and until 2 weeks after RT. The study will include 10 patients. Data on adherence, data acquisition, and biometric data will be collected. Demographic data, objective toxicity scores, and hospitalizations will be documented. ResultsThe primary outcome is to determine if it is feasible for the patients to wear a smartwatch continuously (minimum 12 hours/day) during RT. Furthermore, we will explore how the heart rate and physical activity change over the treatment course. ConclusionsThe study will assess the feasibility of using the Apple Watch for home monitoring of patients with HNC. Our findings may provide novel insights into the patient’s activity levels and variations in heart rate during the treatment course. The knowledge obtained from this study will be essential for further investigating how biometric data can be used as part of symptom monitoring for patients with HNC. Trial RegistrationClinicalTrials.gov NCT04613232; https://clinicaltrials.gov/ct2/show/NCT04613232 International Registered Report Identifier (IRRID)PRR1-10.2196/26096

Published
2021
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2. Electronic Games for Facilitating Social Interaction Between Parents With Cancer and Their Children During Hospitalization: Interdisciplinary Game Development

Author

Piil, Karin, Gyldenvang, Helle Holm, Møller, Jeppe Kilberg, Kjoelsen, Tine, Juul, Jesper, and Pappot, Helle

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundMost cancer treatments today take place in outpatient clinics; however, it might be necessary for some patients to be admitted to hospital departments due to severe side effects or complications. In such situations, support from family and social relations can be crucial for the patients’ emotional well-being. Many young adolescents and children whose parents have cancer describe how they are not seen, heard, or listened to as the worried relatives they are. Within the intensive care unit, it has been recommended that early supportive interventions are tailored to include children of the intensive care patient; a similar approach might be relevant in the oncological setting. To our knowledge, no studies have explored how to involve young relatives who are visiting their parent at an oncological department. Recently, a framework for developing theory-driven, evidence-based serious games for health has been suggested. Such a process would include stakeholders from various disciplines, who only work toward one specific solution. However, it is possible that bringing together different disciplines, such as design, art, and health care, would allow a broader perspective, resulting in improved solutions. ObjectiveThis study aims to develop tools to enhance the social interaction between a parent with cancer and their child when the child visits the parent in the hospital. MethodsIn total, 4 groups of design students within the Visual Design program were tasked with developing games addressing the objective of strengthening relations in situ during treatment. To support their work, the applied methods included professional lectures, user studies, and visual communication (phase I); interviews with the relevant clinicians at the hospital (phase II), co-creative workshops with feedback (phase III), and evaluation sessions with selected populations (phase IV). The activities in the 4 phases were predefined. This modified user design had the child (aged 4-18 years) of a parent with cancer as its primary user. ResultsOverall, 4 different games were designed based on the same information. All games had the ability to make adults with cancer and their children interact on a common electronic platform with a joint goal. However, the interaction, theme, and graphical expression differed between the games, suggesting that this is a wide and fertile field to explore. ConclusionsPlaying a game can be an efficient way to create social interaction between a parent with cancer and a child or an adolescent, potentially improving the difficult social and psychological relations between them. The study showed that the development of serious games can be highly dependent on the designers involved and the processes used. This must be considered when a hospital aims to develop multiple games for different purposes.

Published
2021
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3. Usability of a Mobile Phone App Aimed at Adolescents and Young Adults During and After Cancer Treatment: Qualitative Study

Author

Hanghøj, Signe, Boisen, Kirsten A, Hjerming, Maiken, Elsbernd, Abbey, and Pappot, Helle

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

BackgroundAdolescent and young adult (AYA) cancer patients are seldom involved in the process of testing cancer-related apps. As such, knowledge about youth-specific content, functionalities, and design is sparse. As a part of a co-creation process of developing the mobile phone app Kræftværket, AYAs in treatment for cancer and in follow-up participated in a usability think-aloud test of a prototype of the app. Thus, the app was initiated, created, and evaluated by AYAs with cancer experience. ObjectiveThe aim of this study was to explore the results of a think-aloud test administered to see how the prototype of the app Kræftværket was used by AYAs in treatment for cancer and in follow-up, and to investigate the strengths and weaknesses of the app. MethodsA total of 20 AYA cancer patients aged 16 to 29 years (n=10 on treatment, n=10 in follow-up) were provided with the first version of the co-created mobile phone app Kræftværket during a 6-week test period (April-May 2018). After the test period, 15 participated in individual usability think-aloud tests. The tests were video-recorded, transcribed verbatim, and analyzed using a thematic analysis approach. ResultsThe thematic analysis led to the following themes and subthemes: navigation (subthemes: intuition, features, buttons, home page, profile), visual and graphic design (subthemes: overview, text and colors, photos, videos, YouTube), and usefulness (subthemes: notifications, posts, adding). The analysis identified gender differences in app utilization—female participants seemed to be more familiar with parts of the app. The app seemed to be more relevant to AYAs receiving treatment due to app functions such as tracking symptoms and searching for relevant information. Lack of notifications and incorrect counting of posts were perceived as barriers to using the app. ConclusionsUsability testing is crucial to meet the needs of the AYA target audience. AYA cancer apps should preferably be relevant, targeted, and unique, and include a tracking function and AYA-produced videos. Notifications and correct marking and ordering of posts are critical to make apps engaging and dynamic. Further research is recommended to evaluate the Kræftværket app with the input of more AYAs.

Published
2020
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4. Health-Related Quality of Life Before and After Use of a Smartphone App for Adolescents and Young Adults With Cancer: Pre-Post Interventional Study

Author

Pappot, Helle, Assam Taarnhøj, Gry, Elsbernd, Abbey, Hjerming, Maiken, Hanghøj, Signe, Jensen, Marc, and Boisen, Kirsten Arntz

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundAdolescent and young adult (AYA) patients with cancer are a group with underexplored needs throughout treatment and in survivorship. This missing knowledge can influence their quality of life (QoL). Given this fact, we have developed a smartphone app based on a cocreation process and have an investigation of QoL among users planned as part of pilot testing this app. Future research is warranted to determine the effect of mobile health (mHealth) tools such as smartphone apps among the AYA cancer population. ObjectiveThe aim of this study was to investigate the feasibility of a smartphone app among AYA patients with cancer in active treatment and posttreatment, in a pilot test by measuring health-related QoL before and after the use of the app. MethodsParticipants were recruited via the youth support initiative and social organization for AYAs with cancer, Kræftværket, based at Rigshospitalet, University Hospital of Copenhagen, Denmark. Participants were evenly distributed in active treatment and posttreatment groups. After written informed consent, all participants were asked to use the app Kræftværket as they deemed appropriate over a 6-week period. The participants were asked to complete the 30-item European Organization for Research and Treatment of Cancer Quality of Life Questionnaire before and after the 6-week period. The collected QoL data were analyzed with t tests to determine differences between groups and from baseline. ResultsIn total, we enrolled 20 participants, 10 in active treatment and 10 posttreatment (median time after treatment was 4 months) group. Median age of the participants was 25 years. No differences in QoL were seen at baseline (P=.65). The posttreatment group experienced a significant increase in overall QoL after the 6-week period (global QoL: baseline 62.5, SD 22.3; after 6 weeks 80.8, SD 9.7; P=.04). For the group in active treatment, the QoL remained stable throughout the 6 weeks. ConclusionsThis study shows the feasibility and possible effect on QoL associated with the use of an mHealth tool in AYA patients. mHealth support tools are warranted for this population.

Published
2019
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11. Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy

Author

Rosenberg, Jonathan E., Mamtani, Ronac, Sonpavde, Guru P., Loriot, Yohann, Duran, Ignacio, Lee, Jae-Lyun, Matsubara, Nobuaki, Vulsteke, Christof, Castellano, Daniel, Sridhar, Srikala S., Pappot, Helle, Gurney, Howard, Bedke, Jens, van der Heijden, Michiel S., Galli, Luca, Keam, Bhumsuk, Masumori, Naoya, Meran, Johannes, O'Donnell, Peter H., Park, Se Hoon, Grande, Enrique, Sengeløv, Lisa, Uemura, Hiroji, Skaltsa, Konstantina, Campbell, Mary, Matsangou, Maria, Wu, Chunzhang, Hepp, Zsolt, McKay, Caroline, Powles, Thomas, and Petrylak, Daniel P.

Published
2024
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13. Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma

Author

Prosz, Aurel, Duan, Haohui, Tisza, Viktoria, Sahgal, Pranshu, Topka, Sabine, Klus, Gregory T., Börcsök, Judit, Sztupinszki, Zsofia, Hanlon, Timothy, Diossy, Miklos, Vizkeleti, Laura, Stormoen, Dag Rune, Csabai, Istvan, Pappot, Helle, Vijai, Joseph, Offit, Kenneth, Ried, Thomas, Sethi, Nilay, Mouw, Kent W., Spisak, Sandor, Pathania, Shailja, and Szallasi, Zoltan

Published
2023
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17. Patient-reported outcome (PRO) measurements in chronic and malignant diseases: ten years’ experience with PRO-algorithm-based patient-clinician interaction (telePRO) in AmbuFlex

Author

Hjollund, Niels Henrik I., Larsen, Louise Pape, de Thurah, Annette Ladefoged, Grove, Birgith Engelst, Skuladottir, Halla, Linnet, Hanne, Friis, Rasmus Blechingberg, Johnsen, Søren Paaske, May, Ole, Jensen, Annesofie Lunde, Hansen, Troels Krarup, Taarnhøj, Gry Assam, Tolstrup, Lærke Kjær, Pappot, Helle, Ivarsen, Per, Dørflinger, Liv, Jessen, Anne, Sørensen, Nanna Toxvig, Schougaard, Liv Marit Valen, and team, The AmbuFlex

Published
2023
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20. Treatment Patterns and Efficacy of Chemotherapy After Pembrolizumab in Advanced Urothelial Cancer-a Real-World Study in the pre-Antibody-Drug Conjugate Era

Author

Holmsten, Karin, Eknert, Johanna, Öfverholm, Elisabeth, Papantoniou, Dimitrios, Jawdat, Faith, Verbiéné, Ingrida, Laurell, Anna, Jänes, Elin, Sandzén, Johan, Wojtyna-Dziedzic, Elzbieta, Lagstam, Ida, Söderkvist, Karin, Costa Svedman, Fernanda, Liedberg, Fredrik, Bruzelius, Martin, Fransson, Ann-Sofie, Kjellström, Sofia, Omland, Lise Hoej, Pappot, Helle, and Ullén, Anders

Published
2023
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41. Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial

Author

Park, Se Hoon, van der Heijden, Michiel S., Necchi, Andrea, Castellano, Daniel, Bamias, Aristotelis, Lee, Jae Lyun, De Giorgi, Ugo, Bögemann, Martin, Eigl, Bernhard J., Tsiatas, Marinos, Powles, Thomas, Novikov, Andrey, Skoneczna, Iwona, Mukherjee, Som D., Suarez, Cristina, Westgeest, Hans, Fradet, Yves, Flechon, Aude, Ou, Yen-Chuan, Park, Inkeun, Matveev, Vsevolod, Pérez-Valderrama, Begoña, Cheng, Susanna, Frank, Stephen, Gurney, Howard, Anido, Urbano, Hamzaj, Alketa, Retz, Margitta, Sridhar, Srikala, Scagliotti, Giorgio Vittorio, Voortman, Jens, Alekseev, Boris, Alyasova, Anna, Komyakov, Boris, Dumez, Herlinde, Pavic, Michel, Kimura, Go, Mizokami, Atsushi, Osanto, Susanne, Arranz, Jose Angel, Piersma, Djura, Shin, Sang Joon, Karyakin, Oleg, Delgado, Ignacio, Gonzalez, Jose Luis, Pang, See-Tong, Tran, Anna, Lipatov, Oleg, Su, Wen-Pin, Flaig, Thomas, Alva, Ajjai, Park Kyong, Hwa, Kopyltsov, Evgeny, Almagro, Elena, Domenech, Monserrat, Chang, Yen-Hwa, Sautois, Brieuc, Ravaux, Andre, Aravantinos, Gerasimos, Georgoulias, Vasileios, Mulder, Sasja, Kim, Yu Jung, Kater, Fabio, Chevreau, Christine, Tagawa, Scott, Zalewski, Pawel, Joly, Florence, Loriot, Yohann, Hatiboglu, Gencay, Gianni, Luca, Morelli, Franco, Tambaro, Rosa, Hashimoto, Yasuhiro, Nosov, Alexander, Font, Albert, Rodriguez-Vida, Alejo M., Jones, Robert, Vasudev, Naveen, Srinivas, Sandhya, Zhang, Jingsong, Gil, Thierry, Finch, Daygen, Grimm, Marc-Oliver, Su, Yu-Li, Chowdhury, Simon, Hocking, Christopher, Plas, Eugen, North, Scott, Jensen, Niels Viggo, Theodore, Christine, Imkamp, Florian, Peer, Avivit, Kobayashi, Takashi, Sakai, Hideki, Sassa, Naoto, Yoshimura, Kazuhiro, Aarts, Maureen, Ferreira Castro, Ana, Topuzov, Marlen, Rodriguez, Juan Francisco, Vazquez, Federico Jose, Tsai, Yu-Chieh, Crabb, Simon, Hussain, Syed, Bendell, Johanna, Gross-Goupil, Marine, Gwenaelle, Gravis, Berger, Raanan, Statsenko, Galina, Evans, Linda, Drakaki, Alexandra, Somer, Bradley, Davis, Ian, Lynam, James, Borges, Giuliano, Dettino, Aldo, Fay, André P., Martins, Graziella, Zucca, Luis Eduardo, Agerbaek, Mads, Kalofonos, Haralambos, Rosenbaum, Eli, Enokida, Hideki, Kikukawa, Hiroaki, Nishimura, Kazuo, Tamada, Satoshi, Uemura, Motohide, Lopez, Yamil, Gietema, Jourik, Slojewski, Marcin, Fernandes, Isabel, Smolin, Alexey, Mazhar, Danish, Kalebasty, Arash Rezazadeh, Carthon, Bradley, Loidl, Wolfgang, Franke, Fabio, Girotto, Gustavo, Alimohamed, Nimira, Macfarlane, Robyn, Pappot, Helle, Niegisch, Guenter, Mavroudis, Dimitrios, Sella, Avishay, Porta, Camillo, Ebara, Shin, Nakamura, Motonobu, Obara, Wataru, Okuno, Norihiko, Shinohara, Nobuo, Sugimoto, Mikio, Suzuki, Akitaka, Tokuda, Noriaki, Uemura, Hiroji, Yamaguchi, Akito, Ramirez, Francisco, Rozanowski, Pawel, Wiechno, Pawel, Keam, Bhumsuk, Kislov, Nikolay, Plaksin, Denis, Cicin, Irfan, Kumar, Satish, Galsky, Matthew D., Petrylak, Daniel P., Rosales, Joseph, Vaishampayan, Ulka, Culine, Stephane, Papandreou, Christos, Nara, Taketoshi, Erman, Mustafa, Kreiger, Laurence, Janoski, Juliana, Rosa, Diogo, Siqueira, Mariana, Canil, Christina, Sengelov, Lisa, Tourani, Jean-Marc, Arai, Gaku, Hashine, Katsuyoshi, Kawakita, Mutsushi, Nakaigawa, Noboru, Nomi, Hayahito, Shiina, Hiroaki, Suzuki, Hiroyoshi, Yonese, Junji, Kuri, Roberto, Macedo, Eleazar, Rivera, Samuel, Villalobos Prieto, Alberto, Polakiewicz-Gilowska, Anna, Zaucha, Renata, Lopes, Fabio, Ponomarev, Roman, Pomerantz, Mark, Shariat, Shahrokh, Luk, Cynthia, Lesniewski-Kmak, Krzysztof, van der Heijden, Michiel S, Galsky, Matthew D, Petrylak, Daniel P, Ogawa, Osamu, Lee, Jae-Lyun, Eigl, Bernhard J, Mukherjee, Som D, Suárez, Cristina, Fay, André P, Duran, Ignacio, Wildsmith, Sophie, He, Philip, Angra, Natasha, Gupta, Ashok K, Levin, Wendy, and Bellmunt, Joaquim

Published
2020
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44. Impact of multimorbidity and polypharmacy on mortality after cancer: a nationwide registry-based cohort study in Denmark 2005–2017

Author

Thomsen, Mette K., primary, Løppenthin, Katrine B., additional, Bidstrup, Pernille E., additional, Andersen, Elisabeth W., additional, Dalton, Susanne, additional, Petersen, Lone N., additional, Pappot, Helle, additional, Mortensen, Christiane E., additional, Christensen, Mikkel B., additional, Frølich, Anne, additional, Lassen, Ulrik, additional, and Johansen, Christoffer, additional

Published
2023
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45. Effectiveness of a nurse-delivered (FOCUS+) and a web-based (iFOCUS) psychoeducational intervention for people with advanced cancer and their family caregivers (DIAdIC): study protocol for an international randomized controlled trial

Author

Matthys, Orphé, De Vleminck, Aline, Dierickx, Sigrid, Deliens, Luc, Van Goethem, Vincent, Lapeire, Lore, Groenvold, Mogens, Lund, Line, Arnfeldt, Caroline Moeller, Sengeloev, Lisa, Pappot, Helle, Johnsen, Anna Thit, Guerin, Suzanne, Larkin, Philip J., Jordan, Catherine, Connolly, Michael, D’Alton, Paul, Costantini, Massimo, Di Leo, Silvia, Guberti, Monica, Turola, Elena, van der Heide, Agnes, Witkamp, Erika, Rietjens, Judith, van der Wel, Maaike, Brazil, Kevin, Prue, Gillian, Reid, Joanne, Scott, David, Bristowe, Katherine, Harding, Richard, Normand, Charles, May, Peter, Cronin, Catherine, Northouse, Laurel, Hudson, Peter, and Cohen, Joachim

Published
2021
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48. Nature-inspired green spaces to enhance communication between patients and nurses - a qualitative design study.

Author

Piil, Karin, Bager, Louise, Holm Gyldenvang, Helle, Starklint, Marie, Engberg, Line, Friis-Andersen, Amalie, Højmark-Jensen, Trine, Breitenstein Mathiesen, Ulla, Kjølsen, Tine, and Pappot, Helle

Subjects
HOSPITALS, AESTHETICS, RESEARCH methodology, MEDICAL care, INTERVIEWING, NURSE-patient relationships, QUALITATIVE research, COMMUNICATION, DESCRIPTIVE statistics, RESEARCH funding, HUMAN beings
Abstract

Objective: The aim was to design a setting that promotes privacy of conversations between patients and nurses in hospital hallways, as well as to explore user perspectives on the specially designed hospital space, in addition to the potential effect on a conversation. Background: Many hospitals in Denmark face challenges with outdated infrastructure and lack of facilities creating a welcoming atmosphere for patients and users. Methods: A design thinking process guided the development of nature-inspired seating. The real-scale prototypes were evaluated in semi-structured interviews for perspectives from cancer patients (n = 10) and nurses (n = 8). Results: The aesthetic environment of these spaces improved conversations between patients and nurses, fostering a more conducive atmosphere for communication. These spaces effectively contrasted the clinical hospital setting, signalling a more welcoming environment. Conclusion: Nature-inspired spaces not only offer a sense of privacy but also create an environment that fosters relaxation and concentrated communication. [ABSTRACT FROM AUTHOR]

Published
2024
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49. Patient Engagement in Research Scale (PEIRS-22) - Danish translation, applicability, and user experience among cancer patients and caregivers

Author

Christiansen, Mille Guldager, primary, Pappot, Helle, additional, Hamilton, Clayon, additional, Lund-Jacobsen, Trine, additional, Kristensen, Anne Wilhøft, additional, Nordentoft, Sara, additional, Høeg, Beverley Lim, additional, Bidstrup, Pernille, additional, Nielsen, Iben Husted, additional, Ulstrup, Jane, additional, Trip, Anouk Kirsten, additional, Jarden, Mary, additional, and Piil, Karin, additional

Published
2023
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