1. Use of edoxaban in clinical practice: Comparison of data from the Spanish population in the ETNA-AF-Europe registry.
- Author
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Barón-Esquivias, Gonzalo, Roldán Rabadán, Inmaculada, García Quintana, Antonio, Cerezo Manchado, Juan José, Antorrena Miranda, Isabel, Gómez-Barrado, José Javier, Pérez Paredes, Matías, Santas, Enrique, Pindado Rodríguez, Javier, Muñoz-Robles, Jorge Andrés, Oliver-Miñarro, Desamparados, Santamaría, Amparo, Rabadán, Inmaculada Roldán, Quintana, Antonio García, Miranda, Isabel Antorrena, Paredes, Matías Pérez, Rodríguez, Javier Pindado, and investigators of ETNA AF Spain
- Subjects
PYRIDINE ,RESEARCH ,STROKE ,RESEARCH methodology ,ATRIAL fibrillation ,ANTICOAGULANTS ,ACQUISITION of data ,MEDICAL cooperation ,EVALUATION research ,COMPARATIVE studies ,THIAZOLES ,LONGITUDINAL method - Abstract
Aim: To ascertain the clinical profile and management of edoxaban in clinical practice. Materials & methods: Prospective, noninterventional postauthorization study of nonselected patients with atrial fibrillation treated with edoxaban from 12 European countries. Patients' baseline characteristics are presented. Results: A total of 13,638 patients (73.6 ± 9.5 years; 76.6/23.4% edoxaban 60/30 mg; CHA2DS2-VASc 3.1; 838 [6.1%] from Spain) were included. In Spain, the percentage of very elderly and fragile patients was greater and the risk of thromboembolism (CHA2DS2-VASc ≥2, 98.0 vs 87.3%; p < 0.001) and bleeding (HAS-BLED, 3.2 vs 2.7; p < 0.001) was greater in patients treated with edoxaban 30 mg. The proportion of patients taking edoxaban 30 mg was similar than in ENGAGE AF-TIMI 48. Conclusion: In Spain, patients treated with edoxaban were older and fragile. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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