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1. The Overweight Paradox: Impact of Body Mass Index on Patients Undergoing VATS Lobectomy or Segmentectomy

Author

Parini, Sara, Azzolina, Danila, Massera, Fabio, Mastromarino, Maria Giovanna, Papalia, Esther, Baietto, Guido, Curcio, Carlo, Crisci, Roberto, Rena, Ottavio, Alloisio, Marco, Amore, Dario, Ampollini, Luca, Ardò, Nicoletta, Argnani, Desideria, Baisi, Alessandro, Bandiera, Alessandro, Benato, Cristiano, Benvenuti, Mauro Roberto, Bertani, Alessandro, Bortolotti, Luigi, Bottoni, Edoardo, Breda, Cristiano, Camplese, Pierpaolo, Carbognani, Paolo, Cardillo, Giuseppe, Carleo, Francesco, Cavallesco, Giorgio, Cherchi, Roberto, De Palma, Angela, Dell'Amore, Andrea, Della Beffa, Vittorio, Divisi, Duilio, Dolci, Giampiero, Droghetti, Andrea, Ferrari, Paolo, Fontana, Diego, Gasparri, Roberto, Gavezzoli, Diego, Ghisalberti, Marco, Giovanardi, Michele, Gonfiotti, Alessandro, Guerrera, Francesco, Imperatori, Andrea, Infante, Maurizio, Lausi, Paolo, Lo Giudice, Fabio, Londero, Francesco, Lopez, Camillo, Mancuso, Maurizio, Maniscalco, Pio, Margaritora, Stefano, Marulli, Giuseppe, Mazza, Federico, Meacci, Elisa, Melloni, Giulio, Morelli, Angelo, Mucilli, Felice, Natali, Pamela, Negri, Giampiero, Nicotra, Samuele, Nosotti, Mario, Paladini, Piero, Pariscenti, Gianluca, Perkmann, Reinhold, Pernazza, Fausto, Pirondini, Emanuele, Puma, Francesco, Raveglia, Federico, Refai, Majed, Rinaldo, Alessandro, Risso, Carlo, Rizzardi, Giovanna, Rotolo, Nicola, Scarci, Marco, Solli, Piergiorgio, Sollitto, Francesco, Spaggiari, Lorenzo, Stefani, Alessandro, Stella, Franco, Surrente, Corrado, Tancredi, Giorgia, Terzi, Alberto, Torre, Massimo, Tosi, Davide, Vinci, Damiano, Viti, Andrea, Voltolini, Luca, and Zaraca, Francesco

Published
2023
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2. CD34+DNAM-1brightCXCR4+ haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells

Author

Perrone, Carola, primary, Bozzano, Federica, additional, Dal Bello, Maria Giovanna, additional, Del Zotto, Genny, additional, Antonini, Francesca, additional, Munari, Enrico, additional, Maggi, Enrico, additional, Moretta, Francesca, additional, Farshchi, Alireza Hajabbas, additional, Pariscenti, Gianluca, additional, Tagliamento, Marco, additional, Genova, Carlo, additional, Moretta, Lorenzo, additional, and De Maria, Andrea, additional

Published
2024
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3. Post-operative outcomes and quality of life assessment after thoracoscopic lobectomy for Non-small-cell lung cancer in octogenarians: Analysis from a national database

Author

Alloisio, Marco, Amore, Dario, Ampollini, Luca, Andreetti, Claudio, Argnani, Desideria, Baietto, Guido, Bandiera, Alessandro, Benato, Cristiano, Benvenuti, Mauro Roberto, Bertani, Alessandro, Bertolaccini, Luca, Bortolotti, Luigi, Bottoni, Edoardo, Breda, Cristiano, Camplese, Pierpaolo, Carbognani, Paolo, Cardillo, Giuseppe, Casadio, Caterina, Cavallesco, Giorgio, Cherchi, Roberto, Crisci, Roberto, Curcio, Carlo, Dell’Amore, Andrea, Della Beffa, Vittorio, Dolci, Giampiero, Droghetti, Andrea, Ferrari, Paolo A., Fontana, Diego, Gargiulo, Gaetano, Gasparri, Roberto, Gavezzoli, Diego, Ghisalberti, Marco, Giovanardi, Michele, Gonfiotti, Alessandro, Guerrera, Francesco, Imperatori, Andrea, Infante, Maurizio, Iurilli, Luciano, Lausi, Paolo, Lo Giudice, Fabio, Londero, Francesco, Luzzi, Luca, Lopez, Camillo, Mancuso, Maurizio, Maniscalco, Pio, Margaritora, Stefano, Meacci, Elisa, Melloni, Giulio, Morelli, Angelo, Mucilli, Felice, Natali, Pamela, Negri, Giampiero, Nicotra, Samuele, Nosotti, Mario, Pariscenti, Gianluca, Perkmann, Reinhold, Pernazza, Fausto, Pirondini, Emanuele, Poggi, Camilla, Puma, Francesco, Refai, Majed, Rinaldo, Alessandro, Rizzardi, Giovanna, Rosso, Lorenzo, Rotolo, Nicola, Russo, Emanuele, Sabbatini, Armando, Scarci, Marco, Spaggiari, Lorenzo, Stefani, Alessandro, Solli, Piergiorgio, Surrente, Corrado, Terzi, Alberto, Torre, Massimo, Vinci, Damiano, Viti, Andrea, Voltolini, Luca, Zaccagna, Gino, Zaraca, Francesco, Bongiolatti, Stefano, and Borgianni, Sara

Published
2021
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4. CD34+DNAM-1brightCXCR4+ haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells.

Author

Perrone, Carola, Bozzano, Federica, Dal Bello, Maria Giovanna, Del Zotto, Genny, Antonini, Francesca, Munari, Enrico, Maggi, Enrico, Moretta, Francesca, Farshchi, Alireza Hajabbas, Pariscenti, Gianluca, Tagliamento, Marco, Genova, Carlo, Moretta, Lorenzo, and De Maria, Andrea

Subjects
KILLER cells, T cells, CXCR4 receptors, CHEMOKINE receptors, BONE marrow, GINGER
Abstract

Background: There is little information on the trajectory and developmental fate of Lin-CD34+DNAM-1bright CXCR4+ progenitors exiting bone marrow during systemic inflammation. Objective: To study Lin-CD34+DNAM-1bright CXCR4+ cell circulation in cancer patients, to characterize their entry into involved lung tissue and to characterize their progenies. Methods: Flow cytometric analysis of PBMC from 18 patients with lung cancer on samples collected immediately before the first and the second treatment was performed to study Lin-CD34+DNAM-1bright CXCR4+ precursors. Precursors were purified (>99%) and cultured in vitro from all patients. Paired PBMC and tissue samples from patients undergoing tumor resection were analyzed by flow cytometry to assess tissue entry and compare phenotype and developmental potential of Lin-CD34+DNAM-1bright CXCR4+ cells in both compartments. Results: Significant circulation of Lin-CD34+DNAM-1bright CXCR4+ precursors was observed 20d after the first treatment. Precursors express CXC3CR1, CXCR3, CXCR1 consistent with travel towards inflamed tissues. Flowcytometric analysis of lung tissue samples showed precursor presence in all patients in tumor and neighboring uninvolved areas. Successful purification and in vitro culture from both blood and lung tissue generates a minor proportion of maturing NK cells (<10%) and a predominant proportion (>85%) of a/b T-progenies with innate-like phenotype expressing NKG2D,NKp30,DNAM-1. Innate-like maturing T-cells in vitro are cytotoxic, can be triggered via NKR/TCR co-stimulation and display broad spectrum Th1,Th2 and Th1/Th17 cytokine production. Conclusion: In advanced stage lung cancer CD34+DNAM-1brightCXCR4+ inflammatory precursors increase upon treatment, enter involved tissues, generate functional progenies and may thus represent an additional player contributing to immune balance in the highly SDF-1/CXCR4-biased prometastatic tumor microenvironment. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Surgical Resection of Pulmonary Metastases from Melanoma in Oligometastatic Patients: Results from a Multicentric Study in the Era of Immunoncology and Targeted Therapy

Author

Meacci, Elisa, primary, Nachira, Dania, additional, Congedo, Maria Teresa, additional, Ibrahim, Mohsen, additional, Pariscenti, Gianluca, additional, Petrella, Francesco, additional, Casiraghi, Monica, additional, De Stefani, Alessandro, additional, del Regno, Laura del, additional, Peris, Ketty, additional, Triumbari, Elizabeth Katherine Anna, additional, Schinzari, Giovanni, additional, Rossi, Ernesto, additional, Petracca-Ciavarella, Leonardo, additional, Vita, Maria Letizia, additional, Chiappetta, Marco, additional, Siciliani, Alessandra, additional, Peritore, Valentina, additional, Manitto, Mattia, additional, Morelli, Lucia, additional, Zanfrini, Edoardo, additional, Tabacco, Diomira, additional, Calabrese, Giuseppe, additional, Bardoni, Claudia, additional, Evangelista, Jessica, additional, Spaggiari, Lorenzo, additional, and Margaritora, Stefano, additional

Published
2023
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6. Resected pN1 non-small cell lung cancer: recurrence patterns and nodal risk factors may suggest selection criteria for post-operative radiotherapy

Author

Borghetti, Paolo, Barbera, Fernando, Bonù, Marco Lorenzo, Trevisan, Francesca, Ciccarelli, Stefano, Vitali, Paola, Maddalo, Marta, Triggiani, Luca, Pasinetti, Nadia, Pedretti, Sara, Bonetti, Bartolomea, Pariscenti, Gianluca, Tironi, Andrea, Caprioli, Alberto, Buglione, Michela, and Magrini, Stefano Maria

Published
2016
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7. The Overweight Paradox: Impact of Body Mass Index on Patients Undergoing VATS Lobectomy or Segmentectomy

Author

Parini, Sara, primary, Azzolina, Danila, additional, Massera, Fabio, additional, Mastromarino, Maria Giovanna, additional, Papalia, Esther, additional, Baietto, Guido, additional, Curcio, Carlo, additional, Crisci, Roberto, additional, Rena, Ottavio, additional, Alloisio, Marco, additional, Amore, Dario, additional, Ampollini, Luca, additional, Ardò, Nicoletta, additional, Argnani, Desideria, additional, Baisi, Alessandro, additional, Bandiera, Alessandro, additional, Benato, Cristiano, additional, Benvenuti, Mauro Roberto, additional, Bertani, Alessandro, additional, Bortolotti, Luigi, additional, Bottoni, Edoardo, additional, Breda, Cristiano, additional, Camplese, Pierpaolo, additional, Carbognani, Paolo, additional, Cardillo, Giuseppe, additional, Carleo, Francesco, additional, Cavallesco, Giorgio, additional, Cherchi, Roberto, additional, De Palma, Angela, additional, Dell'Amore, Andrea, additional, Della Beffa, Vittorio, additional, Divisi, Duilio, additional, Dolci, Giampiero, additional, Droghetti, Andrea, additional, Ferrari, Paolo, additional, Fontana, Diego, additional, Gasparri, Roberto, additional, Gavezzoli, Diego, additional, Ghisalberti, Marco, additional, Giovanardi, Michele, additional, Gonfiotti, Alessandro, additional, Guerrera, Francesco, additional, Imperatori, Andrea, additional, Infante, Maurizio, additional, Lausi, Paolo, additional, Lo Giudice, Fabio, additional, Londero, Francesco, additional, Lopez, Camillo, additional, Mancuso, Maurizio, additional, Maniscalco, Pio, additional, Margaritora, Stefano, additional, Marulli, Giuseppe, additional, Mazza, Federico, additional, Meacci, Elisa, additional, Melloni, Giulio, additional, Morelli, Angelo, additional, Mucilli, Felice, additional, Natali, Pamela, additional, Negri, Giampiero, additional, Nicotra, Samuele, additional, Nosotti, Mario, additional, Paladini, Piero, additional, Pariscenti, Gianluca, additional, Perkmann, Reinhold, additional, Pernazza, Fausto, additional, Pirondini, Emanuele, additional, Puma, Francesco, additional, Raveglia, Federico, additional, Refai, Majed, additional, Rinaldo, Alessandro, additional, Risso, Carlo, additional, Rizzardi, Giovanna, additional, Rotolo, Nicola, additional, Scarci, Marco, additional, Solli, Piergiorgio, additional, Sollitto, Francesco, additional, Spaggiari, Lorenzo, additional, Stefani, Alessandro, additional, Stella, Franco, additional, Surrente, Corrado, additional, Tancredi, Giorgia, additional, Terzi, Alberto, additional, Torre, Massimo, additional, Tosi, Davide, additional, Vinci, Damiano, additional, Viti, Andrea, additional, Voltolini, Luca, additional, and Zaraca, Francesco, additional

Published
2022
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8. Post-operative outcomes and quality of life assessment after thoracoscopic lobectomy for Non-small-cell lung cancer in octogenarians: Analysis from a national database

Author

Bongiolatti, Stefano, primary, Gonfiotti, Alessandro, additional, Borgianni, Sara, additional, Crisci, Roberto, additional, Curcio, Carlo, additional, Voltolini, Luca, additional, Alloisio, Marco, additional, Amore, Dario, additional, Ampollini, Luca, additional, Andreetti, Claudio, additional, Argnani, Desideria, additional, Baietto, Guido, additional, Bandiera, Alessandro, additional, Benato, Cristiano, additional, Benvenuti, Mauro Roberto, additional, Bertani, Alessandro, additional, Bertolaccini, Luca, additional, Bortolotti, Luigi, additional, Bottoni, Edoardo, additional, Breda, Cristiano, additional, Camplese, Pierpaolo, additional, Carbognani, Paolo, additional, Cardillo, Giuseppe, additional, Casadio, Caterina, additional, Cavallesco, Giorgio, additional, Cherchi, Roberto, additional, Dell’Amore, Andrea, additional, Della Beffa, Vittorio, additional, Dolci, Giampiero, additional, Droghetti, Andrea, additional, Ferrari, Paolo A., additional, Fontana, Diego, additional, Gargiulo, Gaetano, additional, Gasparri, Roberto, additional, Gavezzoli, Diego, additional, Ghisalberti, Marco, additional, Giovanardi, Michele, additional, Guerrera, Francesco, additional, Imperatori, Andrea, additional, Infante, Maurizio, additional, Iurilli, Luciano, additional, Lausi, Paolo, additional, Lo Giudice, Fabio, additional, Londero, Francesco, additional, Luzzi, Luca, additional, Lopez, Camillo, additional, Mancuso, Maurizio, additional, Maniscalco, Pio, additional, Margaritora, Stefano, additional, Meacci, Elisa, additional, Melloni, Giulio, additional, Morelli, Angelo, additional, Mucilli, Felice, additional, Natali, Pamela, additional, Negri, Giampiero, additional, Nicotra, Samuele, additional, Nosotti, Mario, additional, Pariscenti, Gianluca, additional, Perkmann, Reinhold, additional, Pernazza, Fausto, additional, Pirondini, Emanuele, additional, Poggi, Camilla, additional, Puma, Francesco, additional, Refai, Majed, additional, Rinaldo, Alessandro, additional, Rizzardi, Giovanna, additional, Rosso, Lorenzo, additional, Rotolo, Nicola, additional, Russo, Emanuele, additional, Sabbatini, Armando, additional, Scarci, Marco, additional, Spaggiari, Lorenzo, additional, Stefani, Alessandro, additional, Solli, Piergiorgio, additional, Surrente, Corrado, additional, Terzi, Alberto, additional, Torre, Massimo, additional, Vinci, Damiano, additional, Viti, Andrea, additional, Zaccagna, Gino, additional, and Zaraca, Francesco, additional

Published
2021
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9. Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study

Author

Shi, Jianxin, Hua, Xing, Zhu, Bin, Ravichandran, Sarangan, Wang, Mingyi, Nguyen, Cu, Brodie, Seth A., Palleschi, Alessandro, Alloisio, Marco, Pariscenti, Gianluca, Jones, Kristine, Zhou, Weiyin, Bouk, Aaron J., Boland, Joseph, Hicks, Belynda, Risch, Adam, Bennett, Hunter, Luke, Brian T., Song, Lei, Duan, Jubao, Liu, Pengyuan, Kohno, Takashi, Chen, Qingrong, Meerzaman, Daoud, Marconett, Crystal, Laird-Offringa, Ite, Mills, Ian, Caporaso, Neil E., Gail, Mitchell H., Pesatori, Angela C., Consonni, Dario, Bertazzi, Pier Alberto, Chanock, Stephen J., and Landi, Maria Teresa

Subjects
Lung cancer -- Genetic aspects -- Development and progression, Adenocarcinoma -- Genetic aspects -- Development and progression, Gene mutation -- Health aspects, Gene expression -- Health aspects, Biological sciences
Abstract

Background Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and has a high risk of distant metastasis at every disease stage. We aimed to characterize the genomic landscape of LUAD and identify mutation signatures associated with tumor progression. Methods and Findings We performed an integrative genomic analysis, incorporating whole exome sequencing (WES), determination of DNA copy number and DNA methylation, and transcriptome sequencing for 101 LUAD samples from the Environment And Genetics in Lung cancer Etiology (EAGLE) study. We detected driver genes by testing whether the nonsynonymous mutation rate was significantly higher than the background mutation rate and replicated our findings in public datasets with 724 samples. We performed subclonality analysis for mutations based on mutant allele data and copy number alteration data. We also tested the association between mutation signatures and clinical outcomes, including distant metastasis, survival, and tumor grade. We identified and replicated two novel candidate driver genes, POU class 4 homeobox 2 (POU4F2) (mutated in 9 [8.9%] samples) and ZKSCAN1 (mutated in 6 [5.9%] samples), and characterized their major deleterious mutations. ZKSCAN1 was part of a mutually exclusive gene set that included the RTK/RAS/RAF pathway genes BRAF, EGFR, KRAS, MET, and NF1, indicating an important driver role for this gene. Moreover, we observed strong associations between methylation in specific genomic regions and somatic mutation patterns. In the tumor evolution analysis, four driver genes had a significantly lower fraction of subclonal mutations (FSM), including TP53 (p = 0.007), KEAP1 (p = 0.012), STK11 (p = 0.0076), and EGFR (p = 0.0078), suggesting a tumor initiation role for these genes. Subclonal mutations were significantly enriched in APOBEC-related signatures (p < 2.5x10.sup.-50). The total number of somatic mutations (p = 0.0039) and the fraction of transitions (p = 5.5x10.sup.-4) were associated with increased risk of distant metastasis. Our study's limitations include a small number of LUAD patients for subgroup analyses and a single-sample design for investigation of subclonality. Conclusions These data provide a genomic characterization of LUAD pathogenesis and progression. The distinct clonal and subclonal mutation signatures suggest possible diverse carcinogenesis pathways for endogenous and exogenous exposures, and may serve as a foundation for more effective treatments for this lethal disease. LUAD's high heterogeneity emphasizes the need to further study this tumor type and to associate genomic findings with clinical outcomes., Author(s): Jianxin Shi 1, Xing Hua 1, Bin Zhu 1, Sarangan Ravichandran 2, Mingyi Wang 1,3, Cu Nguyen 4, Seth A. Brodie 1,3, Alessandro Palleschi 5, Marco Alloisio 6, Gianluca [...]

Published
2016
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11. Multicentric study of endobronchial ultrasound-transbronchial needle aspiration for lung cancer staging in Italy

Author

Rotolo, Nicola, primary, Imperatori, Andrea, additional, Nosotti, Mario, additional, Santambrogio, Luigi, additional, Palleschi, Alessandro, additional, Dominioni, Lorenzo, additional, Crosta, Giorgio, additional, Foccoli, Pierfranco, additional, Pariscenti, Gianluca, additional, Passera, Eliseo, additional, Bortolotti, Luigi, additional, Falezza, Giovanni, additional, Infante, Maurizio, additional, Daffrè, Elisa, additional, Cattoni, Maria, additional, and Rosso, Lorenzo, additional

Published
2017
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12. Pleurectomy–decortication in malignant pleural mesothelioma: are different surgical techniques associated with different outcomes? Results from a multicentre study†

Author

Marulli, Giuseppe, primary, Breda, Cristiano, additional, Fontana, Paolo, additional, Ratto, Giovanni Battista, additional, Leoncini, Giacomo, additional, Alloisio, Marco, additional, Infante, Maurizio, additional, Luzzi, Luca, additional, Paladini, Piero, additional, Oliaro, Alberto, additional, Ruffini, Enrico, additional, Benvenuti, Mauro Roberto, additional, Pariscenti, Gianluca, additional, Spaggiari, Lorenzo, additional, Casiraghi, Monica, additional, Rusca, Michele, additional, Carbognani, Paolo, additional, Ampollini, Luca, additional, Facciolo, Francesco, additional, Leuzzi, Giovanni, additional, Mucilli, Felice, additional, Camplese, Pierpaolo, additional, Romanello, Paola, additional, Perissinotto, Egle, additional, and Rea, Federico, additional

Published
2017
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13. Prognostic Score of Long-Term Survival After Surgery for Malignant Pleural Mesothelioma: A Multicenter Analysis

Author

Leuzzi, Giovanni, primary, Rea, Federico, additional, Spaggiari, Lorenzo, additional, Marulli, Giuseppe, additional, Sperduti, Isabella, additional, Alessandrini, Gabriele, additional, Casiraghi, Monica, additional, Bovolato, Pietro, additional, Pariscenti, Gianluca, additional, Alloisio, Marco, additional, Infante, Maurizio, additional, Pagan, Vittore, additional, Fontana, Paolo, additional, Oliaro, Alberto, additional, Ruffini, Enrico, additional, Ratto, Giovanni Battista, additional, Leoncini, Giacomo, additional, Sacco, Rocco, additional, Mucilli, Felice, additional, and Facciolo, Francesco, additional

Published
2015
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15. CD34 + DNAM-1 bright CXCR4 + haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells.

Author

Perrone C, Bozzano F, Dal Bello MG, Del Zotto G, Antonini F, Munari E, Maggi E, Moretta F, Farshchi AH, Pariscenti G, Tagliamento M, Genova C, Moretta L, and De Maria A

Subjects
Humans, Killer Cells, Natural, Bone Marrow, Lung, Tumor Microenvironment, Receptors, CXCR4, Leukocytes, Mononuclear, Lung Neoplasms drug therapy
Abstract

Background: There is little information on the trajectory and developmental fate of Lin - CD34 + DNAM-1 bright CXCR4 + progenitors exiting bone marrow during systemic inflammation., Objective: To study Lin - CD34 + DNAM-1 bright CXCR4 + cell circulation in cancer patients, to characterize their entry into involved lung tissue and to characterize their progenies., Methods: Flow cytometric analysis of PBMC from 18 patients with lung cancer on samples collected immediately before the first and the second treatment was performed to study Lin - CD34 + DNAM-1 bright CXCR4 + precursors. Precursors were purified (>99%) and cultured in vitro from all patients. Paired PBMC and tissue samples from patients undergoing tumor resection were analyzed by flow cytometry to assess tissue entry and compare phenotype and developmental potential of Lin - CD34 + DNAM-1 bright CXCR4 + cells in both compartments., Results: Significant circulation of Lin - CD34 + DNAM-1 bright CXCR4 + precursors was observed 20d after the first treatment. Precursors express CXC3CR1, CXCR3, CXCR1 consistent with travel towards inflamed tissues. Flowcytometric analysis of lung tissue samples showed precursor presence in all patients in tumor and neighboring uninvolved areas. Successful purification and in vitro culture from both blood and lung tissue generates a minor proportion of maturing NK cells (<10%) and a predominant proportion (>85%) of α/β T-progenies with innate-like phenotype expressing NKG2D,NKp30,DNAM-1. Innate-like maturing T-cells in vitro are cytotoxic, can be triggered via NKR/TCR co-stimulation and display broad spectrum Th1,Th2 and Th1/Th17 cytokine production., Conclusion: In advanced stage lung cancer CD34 + DNAM-1 bright CXCR4 + inflammatory precursors increase upon treatment, enter involved tissues, generate functional progenies and may thus represent an additional player contributing to immune balance in the highly SDF-1/CXCR4-biased pro-metastatic tumor microenvironment., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Perrone, Bozzano, Dal Bello, Del Zotto, Antonini, Munari, Maggi, Moretta, Farshchi, Pariscenti, Tagliamento, Genova, Moretta and De Maria.)

Published
2024
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