10 results on '"Parmar, Kajal"'
Search Results
2. Prevalence of Methicillin-resistant Staphylococcus aureus and its antibiotic sensitivity in clinical samples in Tertiary Care Hospital.
- Author
-
Parmar, Kajal, Patel, Dhwani, Mavani, Monika, Javadekar, Tanuja, and Patel, Rachana
- Subjects
- *
METHICILLIN-resistant staphylococcus aureus , *STAPHYLOCOCCUS aureus , *STAPHYLOCOCCUS aureus infections , *ANTIBIOTICS , *MICROBIAL sensitivity tests - Abstract
Introduction: Staphylococcus aureus is responsible for causing a variety of human infections, which may range from minor skin diseases to life-threatening infections. It colonizes healthy individuals and causes severe infection in hospitalized patients. Staphylococcus aureus infections used to respond to ß-lactam and related group of antibiotics but the emergence of Methicillin-resistant S. aureus (MRSA) has posed a serious therapeutic challenge. The present study aimed to determine prevalence of Methicillin-resistant Staphylococcus aureus in Dhiraj General Hospital, Gujarat and to determine antibiotic sensitivity pattern of Methicillin resistant Staphylococcus aureus in various samples and to determine inducible clindamycin resistance strains out of Methicillin resistant Staphylococcus aureus at Dhiraj General Hospital. Materials and methods: The present study was conducted in Microbiology Department of SBKS MI and RC during January 2022 to December 2022. The study comprised of 114 coagulase-positive staphylococci (COPS), isolated from a total of 1470 clinical specimens (like pus, blood, urine, high vaginal swab, sputum, etc.) of patients admitted in Dhiraj General hospital attached to SBKS MI and RC, Hospital, Waghodia, Gujarat. All the isolates were identified by standard procedures. Antimicrobial susceptibility test was carried out on each bacterial isolate using the disc diffusion method on Muller Hinton agar (MHA). Data were entered and analyzed statistically. Results: During one year of study period, a total of 1470 positive culture samples were there. Out of that, 114 positive samples of Staphylococcus aureus were isolated. Out of total Staphylococcus aureus positive samples, 24 strains of Methicillin resistant Staphylococcus aureus (MRSA) were detected. Out of total MRSA, 10 inducible clindamycin resistant Staphylococcus aureus were detected. Conclusion: To conclude, we can say that Vancomycin and Teicoplanin is the drug of choice in MRSA patients. As MRSA is an alarming issue for the health system, one should always think about drug sensitivity test before starting treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. Antibiotic Resistant Pattern of threatening pathogen Acinetobacter baumannii in a tertiary care hospital.
- Author
-
Mavani, Monika, Parmar, Kajal, Patel, Dhwani, Javadekar, Tanuja, and Date, Vidya S.
- Subjects
- *
ACINETOBACTER baumannii , *HOSPITAL care , *URINARY tract infections , *TERTIARY care , *ANTIBIOTICS , *ACINETOBACTER infections - Abstract
Introduction: Acinetobacter species are aerobic gram-negative bacteria that are ubiquitous in nature. Being a multidrug-resistant and an invasive pathogen, Acinetobacter baumannii is one of the major causes of nosocomial infections in the current healthcare system. It has been recognized as an agent of pneumonia, septicemia, meningitis, urinary tract and wound infections, and is associated with high mortality. We aimed this study to evaluate resistance pattern of a threatening pathogen i.e., Acinetobacter baumannii. Materials and method: The present study was conducted in Microbiology Department of SBKSMIRC, Dhiraj Hospital, Waghodia, Gujarat during May 2022 to December 2022. This study included all Acinetobacter baumannii isolated from all ages and microbiological specimens which were referred to Central Microbiology Laboratory of Dhiraj Hospital. The Non-Lactose fermenting, oxidase negative organisms are kept in VITEK 2 automated system for identification and sensitivity. All isolates identified as Acinetobacter baumannii were included in the study. Results: This study included a total of 52 isolates of A.baumannii. Out of which 33% were respiratory samples (sputum, Endo-tracheal secretions), 33% were pus samples, 11% were urine samples and 23% were included in other (blood, CSF, Body fluids). The most resistant drug was ceftriaxone (88.46%). Tigecycline was found to be 100% sensitive. Conclusion: This study concludes that Tigecycline is the only drug which is most sensitive for A. baumannii and other higher drugs such as Polymixin B, Colistin etc. shows less resistance. Acinetobacter infection would remain a therapeutic challenge in our hospital and health care settings due to the increasing rate of Acinetobacter species with traits of MDR and resistance to high potent antimicrobial agents. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Antibiotic Sensitivity Pattern of Burkholderia cepacia complex in blood stream infections in a tertiary care hospital.
- Author
-
Patel, Dhwani, Mavani, Monika, Parmar, Kajal, Javadekar, Tanuja, and Lakhani, Sucheta
- Subjects
BURKHOLDERIA cepacia ,LACTOSE intolerance ,GRAM-negative bacteria ,MICROBIAL sensitivity tests ,TERTIARY care ,TEACHING hospitals - Abstract
Introduction: Burkholderia cepacia complex (BCC) is ubiquitous in nature, present in water, soil, and plants. BCC is comprised of Gram-negative non-lactose-fermenting bacteria. Gram negative, non lactose fermenting Burkholderia cepacia complex has emerged as an opportunistic nosocomial pathogen causing significant morbidity and mortality in hospitalized patients owing to its high antibiotic resistance. This study was aimed to determine prevalence of Burkholderia cepacia complex and to evaluate sensitivity pattern of Burkholderia cepacia complex in blood stream infections in Dhiraj Hospital, Gujarat which is a tertiary care hospital and teaching institute. Materials and Methods: The present study was conducted in the Department of Microbiology for a period from January 2022 to December 2022 of Dhiraj General Hospital, SBKS MI & RC, Waghodia, Gujarat. All samples were received in central laboratory and blood cultures were processed in BD BACTEC FX40. The positive culture bottles were sub cultured on Mac Conkey agar, Blood agar and Nutrient agar and were incubated for 24 hours at 37°C. The data was collected and analyzed statistically. Results: During the study period 31 positive samples for BCC were isolated from a total of 612 culture samples, thus the prevalence rate was 5.06% in our setup. BCC was found majorly in ICUs (65%) and in wards (35%). The isolates showed maximum sensitivity to Co-Trimoxazole (83.87%), followed by Ceftazidime (58.06%), Meropenem (54.83%) and Minocycline (51.61%). Conclusion: From various studies and our study we could conclude that there were variations in the results of drug sensitivity. So, there is need to properly isolate and do antibiotic sensitivity testing for better patient management. Prompt diagnosis is essential step to reduce mortality and establish infection control practices. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
5. Evolution of Mediated Youth Culture: OTT as ‘New Television’ in India
- Author
-
Pandit, Manisha, primary and Parmar, Kajal, additional
- Published
- 2020
- Full Text
- View/download PDF
6. Effectiveness of Structured Teaching Programmed on Knowledge Regarding Chikangunya among BSC Nursing Students at Nootan College of Nursing, Visnagar
- Author
-
N. Sivasubramanian, Ms Ankita Chaudhari, Pargi Manisha, Parmar Chirag, Parmar Diksha, Parmar Ekta, and Parmar Kajal
- Subjects
Chikangunya, Effectiveness, Knowledge, Structured Teaching Programmed - Abstract
“Small bite, Big, Threat”- by who 2014 Chikangunya is a viral disease that could take over chronic symptoms. It has no specific treatment or vaccine to date to evaluate the effectiveness of structured teaching programme of knowledge reading Chikangunya among BSC nursing students at Nootan College of nursing, visnagar. The analysis of data was done by statistics the study identified that 40% had poor level of knowledge, 33.33% had average level of knowledge and 26.67% had adequate knowledge in the Post – Test. The study result presents that Pre- Test Mean value is 13.67 and SD is 6.55. Post- Test Mean value is 16.96 and SD 5.78. The Mean difference is 3.290. The calculated ‘T’ value is 2.069. Which is higher than the table value 1.69. The study conducted that level of knowledge regarding Chikangunya among BSC nursing students found to be increased after structured teaching programme and Post – Test among BSC Nursing student at Nootan college of nursing , Visnagar. 
- Published
- 2022
- Full Text
- View/download PDF
7. Crop Yield Prediction based on Feature Selection and Machine Learners: A Review
- Author
-
Parmar, Kajal P, primary and Bhatt, Tejas, additional
- Published
- 2022
- Full Text
- View/download PDF
8. The Evolution of Mediated Youth Culture: OTT as "New Television" in India.
- Author
-
Parmar, Kajal and Pandit, Manisha
- Subjects
STREAMING video & television - Published
- 2021
9. Evolution of Mediated Youth Culture : OTT as ‘New Television’ in India
- Author
-
Pandit, Manisha and Parmar, Kajal
- Subjects
Social Science - Abstract
Over-The-Top (OTT) platforms are emerging as the ‘New Television’ in India. The report titled ‘Reimagining India’s Media & Entertainment Sector’ published by FICCI and E&Y, 2018 states that OTT subscription is expected to touch 20 billion INR by 2020 in India. The content broadcast over these OTT platforms depict a bold, rough and rugged youth culture crossing the boundaries of sophistication that has remained a part of Indian television screen for a long time. Emergence of transnational OTT platforms like Netflix, Amazon Prime Video, Hulu etc. offer multiple options to the audience for content viewing. The chapter is commentary in nature and aims to address how content streaming on these transnational platforms are framing the new emerging identities of the Indian youth. The protagonists of the stories over these platforms are out rightly rejecting the stereotypical images of young people in the country thus challenging the preoccupied identities of the socio-cultural class distinctions. The chapter attempts to understand contemporary mediated culture and how and in what ways it impacts the young people who are exposed to them regularly. The chapter looks cultural artifacts as complex bundles of mediated images that yield a wide range of responses from people who consumes them.
- Published
- 2019
10. Genetic variation near GRB10 associated with bone growth and osteosarcoma risk in canine and human populations.
- Author
-
Lucas SE, Yang T, Wimberly CE, Parmar KV, Hansen HM, de Smith AJ, Morimoto LM, Metayer C, Ostrom QT, Eward WC, Graves LA, Wagner LM, Wiemels JL, Spector LG, and Walsh KM
- Abstract
Background: Canine and human osteosarcoma are similar in clinical presentation and tumor genomics. Giant breed dogs experience elevated osteosarcoma incidence, and taller stature remains a consistent risk factor for human osteosarcoma. Whether evolutionarily conserved genes contribute to both human and canine osteosarcoma predisposition merits evaluation., Methods: A multi-center sample of childhood osteosarcoma patients and controls underwent genome-wide genotyping and imputation. Ancestry-adjusted SNP associations were calculated within each dataset using logistic regression, then meta-analyzed across the three datasets, totaling 1091 patients and 3026 controls. Ten regions previously associated with canine osteosarcoma risk were mapped to the human genome, spanning ∼6 Mb. We prioritized association testing of 5985 human SNPs mapping to candidate osteosarcoma risk regions detected in Irish wolfhounds, the largest dog breed studied. Secondary analyses explored 6289 additional human SNPs mapping to candidate osteosarcoma risk regions identified in Rottweilers and greyhounds., Results: Fourteen SNPs were associated with human osteosarcoma risk after adjustment for multiple comparisons, all within a 42 kb region of human Chromosome 7p12.1. The lead variant was rs17454681 (OR=1.25, 95 %CI: 1.12-1.39; P=4.1×10
-5 ), and independent risk variants were not observed in conditional analyses. While the associated region spanned 2.1 Mb and contained eight genes in Irish wolfhounds, associations were localized to a 50-fold smaller region of the human genome and strongly implicate GRB10 (growth factor receptor-bound protein 10) in canine and human osteosarcoma predisposition. PheWAS analysis in UK Biobank data identified noteworthy associations of the rs17454681 risk allele with varied measures of height and pubertal timing., Conclusions: Our comparative oncology analysis identified a novel human osteosarcoma risk allele near GRB10, a growth inhibitor that suppresses activated receptor tyrosine kinases including IGF1R, PDGFRB, and EGFR. Epidemiologists may benefit from leveraging cross-species comparisons to identify haplotypes in highly susceptible but genetically homogenous populations of domesticated animals, then fine-mapping these associations in diverse human populations., Competing Interests: Declaration of Competing Interest The authors have no relevant financial or personal interests to report or disclose., (Copyright © 2024 Elsevier Ltd. All rights reserved.)- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.