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3 results on '"Parsa Bazdar"'

1. Contributors

Author

Banafshe Abadi, Nor Hasmaliana binti Abdul Manas, Raquel Silva Araújo, Sayang Baba, Parsa Bazdar, Thomas Beuvier, Muhammad Bilal, Parameswaran Binod, Frank Boury, Nela Buchtová, Juliana Cancino-Bernardi, Valéria Maria de Oliveira Cardoso, Guillermo R. Castro, Zafer Ceylan, Rakshita Chaudhary, Edson José Comparetti, Thomas Cordonnier, María L. Cuestas, Maria Alice de Oliveira, Daniel Joe Dailin, Tomás Brito Devoto, Batul Diwan, Mustafa Durmus, Touba Eslaminejad, João Paulo Fabi, Leonardo Miziara Barboza Ferreira, Natália Ferreira (Noronha), Moreno Galleni, Emmanuel Garcion, Nisha Gaur, Alain Gibaud, Ram K. Gupta, Salehhuddin Hamdan, Zanariah Hashim, Leila N. Hassani, François Hindre, Fitrien Husin, Jayanant Iemsam-arng, Rosli Md. Illias, Christine Jerôme, Norsuhada Abdul Karim, Koray Korkmaz, María F. Ladetto, María J. Limeres, Marina Guimarães Carvalho Machado, Samuel L. Martins, Siti Alyani Binti Mat, Gincy Marina Mathew, Aizi Nor Mazila Ramli, Renata Rank Miranda, Vishal Mishra, Vanessa Carla Furtado Mosqueira, Ida Idayu Muhamad, Mahshid Moballegh Nasery, Hoang Lam Nguyen, Tuan Anh Nguyen, Nor Farahiyah Aman Nor, Ashok Pandey, Sarva Mangala Praveena, Reshmy R, Bathabile Ramalapa, Maria H. Ribeiro, Thiécla Katiane Osvaldt Rosales, Nasrin Seyedpour, Shalyda Shaarani, Raveendran Sindhu, Mohan P Singh, Nidhi Singh, Veer Singh, Deepa Thomas, María A. Toscanini, Yilmaz Ucar, Manisha Verma, Manoj Kumar Verma, Nur Izyan Wan Azelee, Harisun Yaakob, Binti Abang Zaidel, Dayang Norulfairuz Abang Zaidel, Noorazwani Zainol, Siti Fatimah Zaharah Mohd Fuzi, and Valtencir Zucolotto

Published
2022
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3. Resolving interactions of miglitol with normal and glycated human serum albumin by multivariate methods

Author

Parsa Bazdar, Reza Khodarahmi, Ali R. Jalalvand, Vali Akbari, and Héctor C. Goicoechea

Subjects
Chromatography, 1-Deoxynojirimycin, Binding Sites, Chemistry, Miglitol, Biophysics, Serum Albumin, Human, Cell Biology, Electrochemical Techniques, Human serum albumin, Biochemistry, body regions, Chemometrics, Molecular Docking Simulation, Spectrometry, Fluorescence, embryonic structures, medicine, Humans, Spectrophotometry, Ultraviolet, Experimental methods, Molecular Biology, Software, medicine.drug
Abstract

This article reports results of one of our projects related to the investigation of interactions of miglitol (MIG) with normal human serum albumin (HSA) and glycated HSA (GHSA) with the help of recording spectroscopic and electrochemical data. The experimental data were analyzed by conventional and chemometric methods to extract useful information for comprehensive justifications of the interactions of the MIG with HSA and GHSA. Hard- and soft-modeling chemometric methods were used to extract quantitative and qualitative information. Then, molecular docking techniques were used to further investigation of the binding of the MIG with HSA and GHSA and the extracted results were compatible with those obtained by experimental methods. Finally, according to the binding of the BV with HSA and GHSA, second-order differential pulse voltammetric data were recorded and calibrated with three-way calibration methods for exploiting second-order advantage for determination of the GHSA in the presence of the HSA to develop a novel chemometrics assisted-electroanalytical method for diagnostic and monitoring of diabetic.

Published
2021

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