Search

Your search keyword '"Pasanisi, Annamaria"' showing total 13 results
Start Over Author "Pasanisi, Annamaria"
13 results on '"Pasanisi, Annamaria"'

3. Mortality in β-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization

Author

Pinto, Valeria Maria, Musallam, Khaled M., Derchi, Giorgio, Graziadei, Giovanna, Giuditta, Marianna, Origa, Raffaella, Barella, Susanna, Casu, Gavino, Pasanisi, Annamaria, Longo, Filomena, Casale, Maddalena, Miceli, Roberta, Merella, Pierluigi, Tartaglione, Immacolata, Piga, Antonio, Cappellini, Maria Domenica, Gianesin, Barbara, and Forni, Gian Luca

Published
2022
Full Text
View/download PDF

5. Hearing loss in beta‐thalassaemia: An Italian multicentre case–control study.

Author

Manara, Renzo, Brotto, Davide, Barillari, Maria Rosaria, Costa, Giuseppe, Villani, Annalisa Valentina, Perna, Carmine, Ziello, Brunella, di Salle, Francesco, Cantone, Elena, Pasanisi, Annamaria, De Michele, Elisa, Ciancio, Angela, D'Urzo, Giovanna, Valentino, Pasqualina, Perrotta, Silverio, Ricchi, Paolo, and Tartaglione, Immacolata

Subjects
BETA-Thalassemia, HEARING disorders, CHELATION therapy, CASE-control method, BLOOD transfusion reaction, AUDIOMETRY
Abstract

Summary: Background: Despite numerous studies, the true scenario of hearing loss in beta‐thalassaemia remains rather nebulous. Materials and methods: Pure tone audiometry, chelation therapy, demographics and laboratory data of 376 patients (mean age 38.5 ± 16.6 years, 204 females, 66 non‐transfusion‐dependent) and 139 healthy controls (mean age 37.6 ± 17.7 years, 81 females) were collected. Results: Patient and control groups did not differ for age (p = 0.59) or sex (p = 0.44). Hypoacusis rate was higher in patients (26.6% vs. 7.2%; p < 0.00001), correlated with male sex (32.6% in males vs. 21.8% in females; p = 0.01) and it was sensorineural in 79/100. Hypoacusis rate correlated with increasing age (p = 0.0006) but not with phenotype (13/66 non‐transfusion‐dependent vs. 87/310 transfusion‐dependent patients; p = 0.16). Sensorineural‐notch prevalence rate did not differ between patients (11.4%) and controls (12.2%); it correlated with age (p = 0.01) but not with patients' sex or phenotype. Among adult patients without chelation therapy, the sensorineural hypoacusis rate was non‐significantly lower compared to chelation‐treated patients while it was significantly higher compared to controls (p = 0.003). Conclusions: Sensorineural hypoacusis rate is high in beta‐thalassaemia (about 21%) and it increases with age and in males while disease severity or chelation treatment seems to be less relevant. The meaning of sensorineural‐notch in beta‐thalassaemia appears questionable. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

6. 'Phenoconversion' in adult patients with β‐thalassemia.

Author

Musallam, Khaled M., Barella, Susanna, Origa, Raffaella, Ferrero, Giovanni Battista, Lisi, Roberto, Pasanisi, Annamaria, Longo, Filomena, Gianesin, Barbara, Forni, Gian Luca, Pinto, Valeria, Sciortino, Roberta, Roberti, Domenico, De Franceschi, Lucia, and Culcasi, Martina

Published
2024
Full Text
View/download PDF

10. Tricuspid-valve regurgitant jet velocity as a risk factor for death in β-thalassemia

Author

Derchi, Giorgio, primary, Musallam, Khaled M., additional, Pinto, Valeria Maria, additional, Graziadei, Giovanna, additional, Giuditta, Marianna, additional, Barella, Susanna, additional, Origa, Raffaella, additional, Casu, Gavino, additional, Pasanisi, Annamaria, additional, Longo, Filomena, additional, Casale, Maddalena, additional, Miceli, Roberta, additional, Merella, Pierluigi, additional, Gianesin, Barbara, additional, Ameri, Pietro, additional, Tartaglione, Immacolata, additional, Perrotta, Silverio, additional, Piga, Antonio, additional, Cappellini, Maria Domenica, additional, and Forni, Gian Luca, additional

Published
2022
Full Text
View/download PDF

11. Switching from dispersible to film coated tablet formulation of deferasirox improves hemoglobin levels and transfusional interval in patients with transfusion‐dependent‐thalassemia

Author

Quarta, Antonella, primary, Sgherza, Nicola, additional, Pasanisi, Annamaria, additional, Solfrizzi, Maria P., additional, Serra, Marilena, additional, Vitucci, Angelantonio, additional, Dello Iacono, Nicola, additional, Renni, Roberta, additional, Daprile, Carmela, additional, Mosna, Federico, additional, Palma, Antonio, additional, Frappampina, Roberta, additional, Visceglie, Domenico, additional, and Pastore, Domenico, additional

Published
2020
Full Text
View/download PDF

13. Mortality in β-thalassemia patients with confirmed pulmonary arterial hypertension on right heart catheterization

Author

Valeria Maria, Pinto, Khaled M, Musallam, Giorgio, Derchi, Giovanna, Graziadei, Marianna, Giuditta, Raffaella, Origa, Susanna, Barella, Gavino, Casu, Annamaria, Pasanisi, Filomena, Longo, Maddalena, Casale, Roberta, Miceli, Pierluigi, Merella, Immacolata, Tartaglione, Antonio, Piga, Maria Domenica, Cappellini, Barbara, Gianesin, Gian Luca, Forni, Pinto, Valeria M, Musallam, Khaled M, Derchi, Giorgio Egildo, Graziadei, Giovanna, Giuditta, Marianna, Origa, Raffaella, Barella, Susanna, Casu, Gavino, Pasanisi, Annamaria, Longo, Filomena, Casale, Maddalena, Miceli, Robeta, Merella, Pierluigi, Tartaglione, Immacolata, Piga, Antonio, Cappellini, Maria Domenica, Gianesin, Barbara, and Forni, Gian Luca

Subjects
Cardiac Catheterization, Pulmonary Arterial Hypertension, hemic and lymphatic diseases, Immunology, beta-Thalassemia, Humans, Familial Primary Pulmonary Hypertension, Blood Commentary, Cell Biology, Hematology, Biochemistry
Abstract

Pulmonary arterial hypertension (PAH) is a life-threatening complication of β-thalassemia, especially in untransfused patients with thalassemia intermedia. Pinto and colleagues analyzed the outcome of 24 patients with PAH documented by right heart catheterization, and they report that with a median follow-up of 4 years, 54% died, most of which deaths were attributable to PAH. Patients who receive treatment that reduce their pulmonary pressures have improved survival, suggesting that improvement in monitoring and treatment are critical imperatives for these patients.

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results