3 results on '"Patel, Shinal"'
Search Results
2. Efficacy of therapist-delivered transdiagnostic CBT for patients with persistent physical symptoms in secondary care: a randomised controlled trial.
- Author
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Chalder, Trudie, Patel, Meenal, Hotopf, Matthew, Moss-Morris, Rona, Ashworth, Mark, Watts, Katie, David, Anthony S., McCrone, Paul, Husain, Mujtaba, Garrood, Toby, James, Kirsty, Landau, Sabine, Carnemolla, Alisia, Armeanca, Sorina, Couch, Elyse, Ferreira, Nicola, Robertson, Jennifer, Patel, Shinal, Fisher-Smith, Paige, and Childs, Abigale
- Subjects
TREATMENT effectiveness ,RANDOMIZED controlled trials ,MEDICALLY unexplained symptoms ,COST effectiveness ,QUESTIONNAIRES ,RESEARCH funding ,STATISTICAL sampling ,SECONDARY care (Medicine) ,COGNITIVE therapy - Abstract
Background: Medically unexplained symptoms otherwise referred to as persistent physical symptoms (PPS) are debilitating to patients. As many specific PPS syndromes share common behavioural, cognitive, and affective influences, transdiagnostic treatments might be effective for this patient group. We evaluated the clinical efficacy and cost-effectiveness of a therapist-delivered, transdiagnostic cognitive behavioural intervention (TDT-CBT) plus (+) standard medical care (SMC) v. SMC alone for the treatment of patients with PPS in secondary medical care. Methods: A two-arm randomised controlled trial, with measurements taken at baseline and at 9, 20, 40- and 52-weeks post randomisation. The primary outcome measure was the Work and Social Adjustment Scale (WSAS) at 52 weeks. Secondary outcomes included mood (PHQ-9 and GAD-7), symptom severity (PHQ-15), global measure of change (CGI), and the Persistent Physical Symptoms Questionnaire (PPSQ). Results: We randomised 324 patients and 74% were followed up at 52 weeks. The difference between groups was not statistically significant for the primary outcome (WSAS at 52 weeks: estimated difference โ1.48 points, 95% confidence interval from โ3.44 to 0.48, p = 0.139). However, the results indicated that some secondary outcomes had a treatment effect in favour of TDT-CBT + SMC with three outcomes showing a statistically significant difference between groups. These were WSAS at 20 weeks (p = 0.016) at the end of treatment and the PHQ-15 (p = 0.013) and CGI at 52 weeks (p = 0.011). Conclusion: We have preliminary evidence that TDT-CBT + SMC may be helpful for people with a range of PPS. However, further study is required to maximise or maintain effects seen at end of treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. BMC family practice integrated GP care for patients with persistent physical symptoms: feasibility cluster randomised trial.
- Author
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Patel, Meenal, James, Kirsty, Moss-Morris, Rona, Ashworth, Mark, Husain, Mujtaba, Hotopf, Matthew, David, Anthony S., McCrone, Paul, Landau, Sabine, Chalder, Trudie, on behalf of the PRINCE Primary trial team, Ferreira, Nicola, Watts, Katie, Turner, Richard, Carnemolla, Alisia, Robertson, Jennifer, Patel, Shinal, Frank, Philipp, Fisher-Smith, Paige, and Childs, Abigale
- Subjects
BEHAVIOR therapy ,COGNITION ,PATIENT aftercare ,INTEGRATED health care delivery ,HEALTH outcome assessment ,PRIMARY health care ,HEALTH self-care ,PILOT projects ,EFFECT sizes (Statistics) ,RANDOMIZED controlled trials - Abstract
Background: Patients continue to suffer from medically unexplained symptoms otherwise referred to as persistent physical symptoms (PPS). General practitioners (GPs) play a key role in the management of PPS and require further training. Patients are often frustrated with the care they receive. This study aims to assess the acceptability of an 'integrated GP care' approach which consists of offering self-help materials to patients with PPS and offering their GPs training on how to utilise cognitive behavioural skills within their consultations, as well as assessing the feasibility of conducting a future trial in primary care to evaluate its benefit. Methods: A feasibility cluster randomised controlled trial was conducted in primary care, South London, UK. GP practices (clusters) were randomly allocated to 'integrated GP care plus treatment as usual' or 'treatment as usual'. Patients with PPS were recruited from participating GP practices before randomisation. Feasibility parameters, process variables and potential outcome measures were collected at pre-randomisation and at 12- and 24-weeks post-randomisation at cluster and individual participant level. Results: Two thousand nine hundred seventy-eight patients were identified from 18 GP practices. Out of the 424 patients who responded with interest in the study, 164 fully met the eligibility criteria. One hundred sixty-one patients provided baseline data before cluster randomisation and therefore were able to participate in the study. Most feasibility parameters indicated that the intervention was acceptable and a future trial feasible. 50 GPs from 8 GP practices (randomised to intervention) attended the offer of training and provided positive feedback. Scores in GP knowledge and confidence increased post-training. Follow-up rate of patients at 24 weeks was 87%. However estimated effect sizes on potential clinical outcomes were small. Conclusions: It was feasible to identify and recruit patients with PPS. Retention rates of participants up to 24 weeks were high. A wide range of health services were used. The intervention was relatively low cost and low risk. This complex intervention should be further developed to improve patients'/GPs' utilisation of audio/visual and training resources before proceeding to a full trial evaluation. Trial registration: NCT02444520 (ClinicalTrials.gov). [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
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