493 results on '"Patel MM"'
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2. Effect of chemical treatments on shelf life and quality of Aloe vera L. leaves
- Author
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Uppar, Jyoti, primary, Ashok, Yegireedy, additional, Patel, MM, additional, and Chawla, SL, additional
- Published
- 2024
- Full Text
- View/download PDF
3. A comparative study of buccal mucosal cells for cytological changes occurring in smokeless-tobacco exposed population with the non-exposed in the saurashtra region of Gujarat state
- Author
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Sharma, V, Patel, MM, Zaveri, K K, and Singel, TC
- Published
- 2017
4. Analysis of Body Donation in The Saurashtra Region: A Retrospective Study
- Author
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Sharma, V, Zaveri, KK, Patel, MM, Singel, TC, Patel, RK, Patel, RM, and Chudasama, JA
- Published
- 2016
5. Designing and Evaluation of Floating Microspheres of Verapamil Hydrochloride: Effect of Methocel
- Author
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Patel, Manish P, Patel, MM, Patel, KN, Patel, DR, and Patel, UL
- Published
- 2009
6. Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
- Author
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Nepogodiev, D., Matthews, J. H., Morley, G. L., Naumann, D. N., Ball, A., Chauhan, P., Bhanderi, S., Mohamed, I., Glasbey, J. C., Wilkin, R. J. W., Drake, T. M., Clements, J., Blencowe, N. S., Herrod, P. J. J., Pata, F., Frasson, M., Blanco-Colino, R., Soares, A. S., Nepogodiev D, Bhangu A., Matthews, Jh, Morley, Gl, Naumann, Dn, Ball, A, Chauhan, P, Bhanderi, S, Mohamed, I, Glasbey, Jc, Wilkin, R, Drake, Tm, Clements, J, Blencowe, Ns, Herrod, P, Pata, F, Frasson, M, Blanco-Colino, R, Soares, As, Bhangu, A, Nepogodiev, D, Jain, S, Amuthalingam, T, Tyler, R, Griffiths, Ea, Pinkney, Td, Gee, O, Morton, Dg, Beggs, A, Beral, D, Bowley, D, Cruickshank, N, Daniels, I, Griffiths, E, Hornby, St, Lund, Jn, Marriott, P, Singh, P, Smart, Nj, Speake, D, Thompson, C, Torkington, J, Torrance, A, Vohra, R, Warren, O, Winter, Dc, Pellino, G, Sgrò, A, Simioni, A, Farina, V, Podda, M, Di Saverio, S, Birindelli, A, Pasquali, S, Itsurg, Surg, Pt, Bolton, W, Bradshaw, Cj, Chean, Cs, Harris, G, Haddow, Jb, Jamieson, Nb, Mccain, S, Mason, J, Milgrom, D, Nana, Gr, Mohamed, Mn, Brien, Jo, Pearce, J, Rabie, M, Sahnan, K, Sarmah, P, Skerritt, C, Ghazanfar, Ma, Sreedharan, L, Kabwama, S, Gray, Rt, Kamande, Iw, Nazarian, S, Dar, Fa, Misky, At, Arunachalam, S, Twum-Barima, Cs, Mohamed, Im, Connor, Kl, Coe, Po, Kosti, A, Elshaer, M, Colvin, Da, Charalambous, Mp, Yeung, K, Merker, L, Morrison, T, Thaventhiran, Aj, Gilbert, Tm, Clements, Jm, Hicks, G, Afshar, S, Mckinley, Nc, Assaf, N, Hanna, T, Macinnes, E, Thavanesan, N, Dubois, As, Palani-Velu, Lk, Tezas, S, Yow, L, Radwan, Rw, Abdelrahman, M, Lee, Ka, Zarka, Za, Mcdowall, Na, Tan, Cy, Venn, Ml, Ashmore, Dl, Whitehorn, Se, Golder, Am, Reddy, A, Delimpalta, C, Kay, Oh, Shah, Sm, Eiben, I, Doyle, C, Tudyka, V, Issa, E, West, H, Brewer, Hk, Farrow, Ez, Taylor, Ns, Smart, Cj, Griffiths, Np, Halkias, C, Vitish-Sharma, P, Knight, Sr, Mowbray, Ng, Olivier, Jb, Lee, Kj, Clement, Kd, Chrastek, D, Panda, N, Connor, Mj, Fahmy, Se, Bryan, Es, Ngu, Ws, Adegbola, So, Vaughan, Em, Stupalkowska, W, Simmonds, L, Malik, A, Hussein, A, Karim, Mj, Singhal, T, Ormiston, R, Kung, V, Rabie, Ma, Park, Jh, Lal, N, Worku, D, D'Auria, M, Ang, A, Orizu, M, Gammeri, E, Clough, E, Choy, Ch, Lawday, S, Hann, Aj, Robinson, D, Wardle, Bg, Mcdonnell, D, Rutherford, Dg, Hickey, Lm, Garg, Ag, Rezvani, S, Bell, Cr, Mahmood, F, Rehman, S, Donaldson, G, Peleki, A, Pearce, L, Sharp, Ol, Singh, S, Thompson, Db, El-Tayar, O, Hollyman, M, Rupasinghe, Sn, Toomey, Db, Murray, Mp, Amtul, N, Mersh, Rj, Newton, Rc, Al-Khyatt, W, Stephens, Gf, Abbas, Sh, Iqbal, Mr, Brown, Ce, Renshaw, S, Hureibi, Ka, Pullabatla-Venkata, Up, Donohoe, No, Myatt, A, Egan, Rj, Rangarajan, K, Trail, M, Mckay, Sc, Engall, N, Jerome, E, Townsend, Dc, Patel, By, Pronin, S, Chandratreya, N, Choong, Jh, Mohamed, Tm, Hudson-Peacock, Nj, Manson, R, Hebbar, K, Mothe, Bs, Weegenaar, Cr, Saad, M, Bowman, Cr, Serventi, F, Fleres, F, Foppa, C, Pata, G, Baronio, G, Pertile, D, Lucchi, A, Sagnotta, A, Maretto, I, Campagnaro, T, Gatti, M, Gjoni, E, Roscio, F, Inama, M, Coccolini, F, Colombo, F, Avanzolini, A, Aresu, S, De-Manzoni-Garberini, A, Merlini, Da, Chessa, A, Tamini, N, Mulas, S, Cillara, N, Coletta, D, Atzeni, J, Erdas, E, Gallo, G, Francone, E, Di Gioia, P, Bianchi, Cl, Ferrara, F, Biancafarina, A, Scabini, S, Marano, L, Miegge, A, Sasia, D, Savino, G, Scatizzi, M, D'Amico, Fe, Arcuri, Ga, Gavagna, L, Salamone, G, Tatulli, F, Goldin, E, Matos, Ml, Caldeira, Ab, Romano, J, Pereira, J, Azevedo, J, Azevedo, Jm, Simoes, J, Silva, A, O'Leary, Dp, Kennedy, Nd, Quinn, Em, Zhang, Ay, Neary, Pm, De-Marchi, Ja, O'Connor, Br, Wijesundera, K, Foley, Nm, Wong, J, Tiedt, La, Bolger, Jc, Connelly, Tm, Ahmed, Os, Vigorita, V, García, V, Arredondo, J, Redondo, E, Sainz, B, Aldrey, I, Landaluce-Olavarria, A, Gómez, Aa, Cordoba, E, Sánchez-Fuentes, Mn, Cerdán-Santacruz, C, Beltran-De-Heredia, J, García, M, Veres, T, García-Novoa, A, Abellán, Am, García-Catalá, L, Ruiz-Marín, M, Menendez, P, Roldán-Ortiz, S, Navas-Cuéllar, Ja, Sabia, D, Gomez-Rosado, Jc, Navidad, Ms, Caula, C, Sanchez, Er, Espin-Basany, E, Fernández-Martínez, D, Bravo-Gutiérrez, Af, Payá-Llorente, C, Dujovne, P, Lima, F, Soria-Aledo, V, Gomez, Cj, Pascual-Miguelañez, I, Muinelo, M, Alvarez, 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J, Carden, Ca, Makhija, R, Rao, M, Sarveswaran, J, Vijay, V, Rekhraj, S, Knight, B, Siddiqui, Mn, Sebastian, Jf, Glen, P, Vakis, S, Ebied, H, Rajaram, R, Gray, J, Mcgrath, D, Faulkner, G, Gopalswamy, S, Varcada, M, Woodward, A, Williams, Gl, Szentpali, K, Ravindran, R, Bronder, C, Thaha, Ma, Rate, A, Shetty, Vd, Rao, V, Sajid, Ms, Clements, B, Patel, Rt, Mason, C, Branagan, G, Maude, K, Kaur, G, Lyons, A, Ainsworth, P, Hagger, R, Zadi, Az, Maslekar, Su, Kinross, J, Irukulla, S, Hawkins, W, Wheatstone, S, Magro, T, Bailey, S, Marshall, G, Mccullough, J, Marangoni, G, Leung, El, Borg, Cm, Gopinath, S, Kirkby-Bott, J, Yalamarthi, S, Mirza, S, Brett, M, Ramcharan, S, Pandey, V, Thava, B, Andreani, Sm, Sahay, Sj, Aravind, B, Downey, M, Nicol, D, Whitehouse, P, Sharma, A, Francis, N, Chitsabesan, P, Stewart, Dj, Norcia, Gg, Cucinotta, E, Cianchi, F, Romario, Uf, Taglietti, L, Capelli, P, Garulli, G, Parisi, A, Nitti, D, Guglielmi, A, Alonzo, A, Scandroglio, Is, Moretto, G, Ansaloni, L, Pietrabissa, A, Foschi, D, Vettoretto, N, Ercolani, G, Coppola, M, Colangelo, E, Morandi, E, Niolu, P, Pala, M, Coletti, M, Pisanu, A, Nicolosi, A, Sammarco, G, Berti, S, Soliani, P, Tonini, V, Stella, M, Ceccarelli, G, De Nisco, C, Castagnoli, G, De Nardi, P, Borghi, F, Agresta, F, Benevento, A, Cantafio, S, Cesari, Mc, Rubbini, M, Chetta, G, De Marchi, F, Nora, Mf, Sousa, Hs, Nascimento, Ca, Casimiro, C, Costa, Sd, Rosa, Mj, Carvalho, N, Correia, J, Gomes, Ap, Hill, Ad, Walsh, Tn, Aremu, Ma, Mulsow, J, El-Masry, S, Gillick, J, Garvin, J, Caldwell, M, Mehigan, B, Peirce, Cb, Cooke, F, Mealy, K, Ruano, A, Ais, G, Fueyo, J, Parajó, Ae, Bernal-Sprekelsen, Jc, Monzón-Abad, Ja, Blanco, F, Arroyo, A, Bazán-Hinojo, Mc, Ramos-Bernado, Mi, Lopez-Ruiz, Ja, Golda, T, Julià, D, Cuadrado, Mm, Gómez-Abril, Sa, Martinez, J, Aguayo, Jl, Millan, M, Alvarez-Gallego, M, Muinelo-Lorenzo, M, Parra, Jm, Muñoz-Muñoz, E, De Chaves-Rodríguez PG, Cánovas-Moreno, G, Rodriguez-Lopez, M, Segura-Sampedro, Jj, García-Granero, A, Redondo-Calvo, Fj, Dyson, S, Thakur, D, Swords, C, Siaw, O, Zelazek, M, Woo, R, Badran, A, Aruparayil, N, Christopoulos, P, Chambers, B, O'Neill, N, Long, Rh, Mccaughey, P, Wong, Ml, Mccain, Rs, Lennox-Warburton, Hc, Moore, C, Manektella, Km, Mcilwaine, S, Rupani, S, Simpson, Dj, Wauchope, J, Ng, M, Christian, L, Crone, A, Sacks, R, Symons, N, Lazzaro, A, Patil, Sd, Roomi, S, Silva, I, Hodgson, Jm, Ly, C, Froud, H, Patel, H, Cay, P, Karwal, Rs, Danquah-Boateng, D, Berry, B, Esmail, Hd, Maripi, H, Bilku, D, Mckelvie, Ma, Miller, K, Maina, A, Velho, R, Hasan, R, Clingan, R, Jah, S, Waite, K, Jones, A, Buckley-Jones, S, Lecky-Thompson, L, Saghir, N, Mansoor, S, Mistry, D, Brown, R, Wong, A, Gurung, S, Wensley, F, Fleming, Ta, Griggs, R, Haines, S, Bedoya, S, Beverstock, A, Johnson, J, Govind, G, Niaz, O, Dyal, A, Tokidis, E, Punj, S, Leusink, A, Rudland, I, Kelly, M, Morgan, R, Al-Musawi, S, Lek, C, Gilbert, A, Gosal, A, Mahoney, R, Parwaiz, I, Mitchard, Mj, Ribeiro, B, Merai, H, Dean, Ea, Khan, S, Baginski, A, Mann, C, Foers, W, Jones, L, Woodward, B, Mcwhirter, Dm, Thomas, At, Gilbert, Tg, Weatherburn, Lw, Pilkington, Jp, Cameron, Fc, Clements, Jd, Mccann, C, Davidson, S, Hackney, L, Clements, Js, Martin, A, Du, Dt, Shakoor, Z, Yen, Sk, Adnan, M, Ranathunga, S, Sana, S, Tay, Yh, Chin, My, Gillespie, M, Brown, Ag, Campbell, U, Chatzikonstantinou, M, Mahendran, B, Flack, T, Chowdhary, M, Lim, Jm, Whiteman, E, Shepherd, Ja, Pedder, A, Siggens, Kl, Lai, Cw, Morrison-Jones, V, Hayat, Z, Nehikhare, I, Macleod, C, Quinn, Hc, Brown, A, Neagle, G, Chok, Sm, Carrano, Fm, Abbassi, Oa, Divekar, Ga, Halmer, S, Adams, Re, Davies, Pl, Wong, Sy, Amarasinghe, R, Tague, Le, Jones, E, Singh, J, Boza, K, Kelly, Sd, Morrison, F, Chan, Wh, Wilson, Ej, Awokoya, Oo, Griffiths, Sn, Kirkham, En, Cotton, Ae, Adimonye, A, Leighton, Pa, Abdelrahman, A, Cartwright, H, Gates, Z, Miguras, M, Khan, K, Louw, C, Grove, T, Badenoch, T, Mckeon, J, Wood, Cs, Leitch, Rp, Sgardelis, P, Perera, Mi, Nagarajan, D, Malam, Y, Theodoropoulou, K, Rajagopal, S, Kaptanis, S, Popova, D, Olagbaiye, O, Tayeh, S, Rigby, S, Harris, Mp, Ren, Kz, Liaw, G, Zhou, S, White, F, Marshall, Cm, Mitchell, Jh, Anderson, Dj, Kanakala, V, Hollingsworth, A, Paramasevon, Kr, Milward, J, Ahmed, S, Fanibi, Bf, Ferguson, N, Dickson, Ea, Shaw, Av, Dixon, F, Morrish, S, Dandy, R, Fooks, P, Sharma, P, Islam, N, Tabain, V, Keegan, R, Ahel, J, Alhammali, T, Graveston, J, Balai, Ej, Rothnie, K, Pankin, Gp, Eiben, Ie, Jackson, Nj, Dhar, M, Nash, D, Dharamavaram, S, Seth, M, Chowdhury, F, Rezacova, M, Seneviratne, N, Turner, Ej, Currow, C, Isherwood, Jd, Hobson, Bm, Lui, Dh, Rodger, V, Ting, N, Photiou, D, Taze, D, Lodhia, S, Earnshaw, L, Kumar, K, Neale, A, Bastianpillai, J, Cipparrone, M, Barrie, A, Nash, Z, Anandan, L, Tailor, K, Vinnicombe, Z, Krivan, S, Kuo, R, Giorga, A, Habib, H, Malik, K, Bogdan, M, Mahon-Daly, Fp, Athersmith, Mj, Strange, Ja, Wheeler, C, Summerfield, L, Khaw, Ra, Ashour, O, Iosif, E, Fadel, M, Gopalakrishnan, K, Orme, N, Williams, S, Rashid, M, Sultana, A, Patel, N, Pearson, R, Yasin, T, Bevan, V, Al-Sarireh, B, Brown, M, Mohd, N, Howie, Ee, Poudevigne, M, Paget, C, Rallage, H, Chui, K, Fawzi, F, Layman, S, Okorocha, E, Jama, Gm, Orawiec, P, Kouli, O, Hassane, A, Kilkenny, J, Devine, Aa, Laurenson, M, Slezak, I, Barker, T, Lau, E, Limbada, M, O'Brien, J, Weaver, J, Hajibandeh, S, Shah, J, Mansour, Mm, Malik, Sn, Davis, S, Trew, F, Bandyopadhyay, Sk, Dart, K, Guru-Naidu, S, Callan, R, Nair, Mk, Alani, M, Sezen, E, Salim, S, Shurlock, J, Siddique, K, Forouzanfar, A, Brews, R, Acharya, A, Jain, A, Tozer, Pj, Warusavitarne, J, Emslie, Km, Collier-Wakefield, O, Sivaloganathan, P, Dobson, C, Elseedawy, M, Mcnally, L, Williams, M, Motiwala, Fh, Choi, S, Asmadi, Aa, Burnside, D, Everden, A, Suriyakumar, S, Sandu, L, Kent, Da, Bowen, J, Long, P, Khair, A, Shah, K, Phelan, L, Pierre, R, Dhari, Aa, Hoff, M, Nickson, S, Setshwaelo, T, Chalk, A, Parkola, Mj, Harlinska, A, Chan, T, Dudek, Jg, Rolph, R, Allen, M, Pollard, H, Gormely, R, Finlayson, H, Ljungqvist, G, Peponis, C, Rahman, M, Dhesi, S, Arshad, F, Faris, Ar, Sooriyamoorthy, T, Springate, El, Barnieh, W, Patel, As, Siddiqui, Za, Chishti, Ia, Ayube-Brown, J, Rabie, Mr, Blake, L, Yardimci, E, Nagendram, S, Neophytou, Gi, Henderson, L, Farhan-Alanie, M, Kong, Cy, Ghazala, R, Evans, J, Hussain, N, Kabir, M, Hraishawi, I, Cox, M, Bailey, Ja, Muhibullah, N, Yanni, F, Stevenson, R, Nair, A, Murphy, C, Mcgucken, O, Pandya, R, Bowerman, H, Lafaurie, G, Van Boxel GI, Shanmugarajah, K, Maragouthakis, D, Hanif, Z, Evans, Jd, Yoganathan, S, Richardson, Td, Cook, V, Clark, Gl, Rigney, B, O'Neill, E, Guliani, J, Chan, D, Harper, F, Sian, T, Boereboom, C, Blackwell, J, Hardy, E, Boyd-Carson, H, Couch, Dg, Barter, Ca, Thoukididou, Sn, Hatt, Jr, Jones, Cs, Dean, S, Rajaretnam, N, Masood, M, Thakral, N, Griffith, D, Doherty, C, Longshaw, A, Peprah, D, Mathew, G, Hook, A, Vance-Daniel, J, Ibrahim, Y, Walters, Kj, Whewell, He, Sherif, Ma, Mckenna, M, O'Sullivan, D, Woodrow, C, Gill, S, Johnstone, A, Gentry, R, Irwin, R, Forgie, A, Welsh, S, Ivey, P, Bullivant, Jk, English, Wj, Osterberg, A, Morowala, A, Al-Faham, Z, Islam, S, Tan, E, Sadek, S, Sihra, N, Shrestha, D, Chong, B, Nadeem, A, Fasuyi, Ja, Patel, Mm, Daureeawoo, R, Okekunle, B, Cheruvu, M, Mazumdar, E, Hussain, A, Patel, C, Mcquaid, M, Banks, A, Robinson, A, Khan, Ms, Riaz, W, Verroiotou, M, Cohen, Ja, Kouroumpas, E, Ghaffari, I, Moradzadeh, J, Kamal, M, Gulamhussein, M, Gaines, E, Ghatorae, S, Clark, S, Savill, A, Hutchinson, B, Chapman, J, Wu, F, Creasy, W, Raymond, M, Grosvenor, S, Odeh, A, Malik, Y, Bansal, H, Grant, C, Raofi, A, Ahmed, B, Mai, D, Souter, J, Hamelmann, Rn, Ikram, S, Durbacz, M, Gilliland, N, Salem, A, Chudek, D, Ladwa, N, Storey, R, Fontaine, C, Toomey, D, Miller, B, Oakey, M, Smoker, H, Chapman, Sj, O'Hagan, Sc, Tahir, W, Wilcox, G, Ahmad, A, Akram, F, Baddams, Ts, Boshier, Pr, Fehervari, M, Easdon, S, Ilozue, T, Adam, Me, Jokhan, S, Foster, A, Nambiar, K, Bohra, P, Janardanan, S, Shanmuganathan, V, Maqboul, F, Ettles, C, Wardle, Sd, Martinou, E, Khasria, A, Bagga, R, Motter, D, Mundkur, N, Pan, Y, Akbari, K, Farrell, Sm, Rahim, A, Gummaraju, A, Mahmoud, A, Akinsola, O, Smallcombe, N, Tarazi, M, Hanley, C, Campbell, Um, Franklin, D, Davidson, Jr, Raza, Ss, Krishnamoorthy, A, Rajjoub, Y, Ali, M, Seddon, Tc, Payne, Re, Das, A, Martin, Lm, Naismith, Kn, Venkata, Up, Manda, Vm, Burns, Km, Huang, J, Samuel, M, Docherty, Ja, Cheah, Wl, Ooi, R, Nyeko-Lacek, M, Marsh, L, Prideaux, A, Li, Ch, Poacher, A, Lee, M, Muzaffar, M, Kara, A, Walsh, E, Sunter, H, Roth, N, Roy, C, Mcmorran, D, Turnbull, A, Layton, Gr, Archer, Je, Yang, P, Douka, E, Amin, V, Borghol, K, Blackford, Od, Bond, S, Baker, B, Mohamed, Wo, Williams, R, Garnham, J, Robb, Hd, Allington, J, Cloney, L, Tamborska, A, Kalia, K, Fung, E, Johnston, Z, Lynch, L, Christides, A, Tan, Hl, Cynthia, G, Tsang, B, Rossi, C, Kaubrys, M, Al-Khafaji, N, Jenkins, M, Peiris, Gb, Gunning, S, Nimako, E, Pandya, D, Hever, P, Amayo, A, Bull, C, Clements, C, Al-Sheikh, M, Savioli, F, Long, M, Horsfield, E, Robertson, C, Ogboru, S, Mcilwrath, Ac, Bell, J, Limb, C, Obeid, N, Rich, Je, Balasubramaniam, A, Mashar, R, Taylor, M, Bruce, Js, Dennison, G, Curtis, Nj, Ezerska, E, Ellis, B, Wiggill, S, Tee, A, Ng, S, Carder, C, Abdelwahed, A, Chandler, Sb, Tinsley, Bj, Finotti, E, Occhioni, G, Cossu, F, Vulcano, I, Viscosi, F, Michelini, M, Compagnoni, B, Sepe, C, Isolani, Sm, Regina, G, Alagna, V, Martorelli, G, Gabbianelli, C, Moroni, P, Zuin, M, Conci, S, Lazzari, G, Costamagna, D, Zurleni, Tz, Altomare, Ma, Desiderio, J, Di Cintio, A, Gemini, A, Trastulli, S, Viviani, E, Tomasoni, M, Montori, G, Harder, G, Argenti, F, Malabarba, S, Checcacci, P, Montanelli, P, Guerra, F, Skalamera, I, Staderini, F, Grandi, S, Nelli, T, Coratti, F, Sorrentino, L, Maffioli, A, Cavallo, D, Bondurri, A, Groppo, G, Curti, R, Solaini, L, Xidas, A, Manias, T, Delogu, D, Vacca, A, Solinas, L, Corbellini, C, Fiore, L, Nigro, A, Santurro, L, Angrisani, M, Sparta, C, Lorettu, A, Mura, Fa, Ruggiu, Gv, Pirari, Pf, Pau, R, Melis, M, Piu, F, Patti, S, Deserra, A, Angelieri, D, Del Basso, C, Rossi, D, Iannone, I, De Padua, C, Giubilo, C, Falaschi, F, Cirillo, B, Gordini, L, Podda, F, Sanna, S, Saba, A, Poillucci, G, Pinna, E, Messina, A, Sena, G, Cardona, R, De Luca, E, Sacco, R, Vescio, G, Ammendola, M, Romano, R, Bianco, A, Bonfante, P, D'Ambra, L, Feleppa, C, Gennai, A, Lizzi, V, Moggia, E, Imperatore, M, Bolzon, S, Belvedere, A, Amaducci, E, Ripoli, Mc, Segalini, E, Cervellera, M, Vaccari, S, Eretta, Co, O'Neill, R, Llewelyn, O, Jones, N, Clerici, F, Ballabio, M, Andolfi, E, Angelini, M, Fontani, A, Miranda, E, Scricciolo, M, Provenza, G, Pellicanò, Ga, Pulighe, F, Argenio, G, Melis, A, Balestra, F, Anania, M, Cruccu, A, Massaiu, C, Murru, Ml, Martino, A, Luzzi, Ap, La Valle, G, Chillitupa, Cz, Bartoli, A, Conti, D, Spaziani, A, Bellochi, R, Listorti, C, 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E., Espinosa J., Carral-Freire M., Martinez-Almeida R., Santarrufina-Martinez S., Sebastian-Tomas J.C., Gonzalvez-Guardiola P., Fernandez E.C., Mozo A.S., Stoyanov T.I., Santamaria P.C., Grimaldo E.G., Fernandez-Candela A., Curtis-Martinez C., Del-Valle-Ruiz S.R., Sanchez-Cifuentes A., Ramirez-Faraco M., Lopez A.F., Leon C., Kumar S., Fornell-Ariza M., Ayllon-Gamez S., Pena-Barturen C., Ojea-Ruiz-Yherla L., Saavedra-Chacon M., Perez-Calvo J., Gomez-Facundo H., Riba-Combatti L., Manas O.C., De-Soto-Cardenal B., De-La-Herranz-Guerrero P., Dominguez-Sanchez C., Gamero-Huaman J.C., Suarez-Cabrera A., Ramirez-Redondo A.A., Lara-Fernandez Y., Bascuas-Rodrigo B., Lopez-Duran B.L., Pigem A., Gil J., Salvador H., Planellas P., Farres R., Caballero A., Arnau M., Tapiolas I., Ridaura N., Roncero L.S., Collado-Roura F., Fijo L.M., Cormenzana O.B., Vinas N.L., Grifell M.S., Prats M.A., Torrado A.A., Sanz-Navarro S., Contreras-Saiz E., Solar-Garcia L., Moreno-Gijon M., Suarez-Sanchez A., Diaz-Vico T., Rodicio-Miravalles J.L., Garcia-Gutierrez C., Pila U., Melone S., Martin-Prieto L., Rojo J.A., Gonzalez M., Zorrilla L., Garcia-Marin J.A., Baeza-Murcia M., Pellicer-Franco E., Jimenez-Ballester M.A., Asensio-Gomez L., Gortazar-De-Las-Casas S., Guevara-Martinez J., Ramirez L., Verea S., Anguita F., Navarro G., Criado ADC., Lara M.C., Martinez E.T., Sanchez-Martinez A., Hernandez-Gimenez L., Galofre-Recasens M., Ferrer-Vilela I., Perez-Sanchez L.E., Esteves M.B., Menendez-Moreno A., Baz-Figueroa C., Rosat A., Hontoria M.S., Garcia N.A., Gracia-Roman R., Pascua-Sole M., Pino-Perez O., Garcia-Perez J.M., Pineno-Flores C., Ambrona-Zafra D., Sancho-Muriel J., Alvarez E., Jimenez-Rosellon R., Daga O., Alberca-Paramo A., Sanchez-Garcia S., Garcia-Santos E., Pareja-Ciuro F., Olivares-Oliver C., Navarro-Morales L., Tamayo-Lopez M.J., Tinoco-Gonzalez J., Garcia-Rivera C.O., Agua I.A., Moreno-Suero F., Pereira-Mosquera E., Zerpa C., Llacer E., Diaz A., Caro A., Feliu F., Franco M., Escuder J., Abellan M., Padilla E., Mambrilla-Herrero S., Plua-Muniz K.T., Bailon-Cuadrado M., Tejero-Pintor F.J., Choolani-Bhojwani E., Vila-Zarate C., Delgado-Plasencia L.J., Ponchietti L., Cousins L., Busuttil A., Baird C., Drye N., Brown O.D., Mansour S., Anderson O., Mahapatra R., Clements J.A., D'Souza N., Littlehales D.J., Tang A.M., Byrne B.E., Cunha P., Ogbuokiri C., Eiben P., Gravante G., Kho H., Dobbs S., Doulias T., Ng J., Wilson M., Venugopal R., Wolff J., Akhtar K., Walji H.D., Tognarelli J.M., Knight K.A., Ansari A., Hussaini S.A., Wright E., Brewer H., Rinkoff S., Harries R.L., Fairfield C.J., Abbott T., Jackson A., Wright H.L., Walters U., Carney K., Logan P.C., Mughal Z., Strachan E., Chasty B., Ma J., Mazzeo C., Badii B., Armellini A., Grassia M., Perin A., Ruzzenente A., Magnoli M., Depalma N., Longheu A., Papandrea M., Dova L., De Prizio M., Gusai G.P., Di Zitti L., Geretto P., Azabdaftari A., Chianese G., Elbetti C., Ruffolo C., Giaccari S., Devezas V., Ferreira J.S., Peixoto R., Alshafei A., Simo V., Jose H.S., Ugarte-Sierra B., Salva A.B., Gomez N., Marinello F., Medina-Arana V., Vega L., Ballester M.M., Espina B., Prieto-Nieto M.I., Rodriguez E.C., Padilla-Valverde D., and Duran-Munoz-Cruzado V.M.
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Adult ,humanos ,Decision Making ,Risk Assessment ,NO ,apendicectomía ,apendicitis ,evaluación de riesgos ,Appendectomy ,Humans ,hospital ,General ,collaborative ,LS7_4 ,right iliac fossa ,appendicitis ,emergency service ,Original Articles ,adulto ,Appendicitis ,adult ,appendectomy ,humans ,risk assessment ,decision making ,Lower GI ,Original Article ,appendicitis, prediction models, right iliac fossa pain ,Emergency Service, Hospital ,toma de decisión - Abstract
Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P, Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making were identified by identifying UK adults at low risk of appendicitis. An online calculator is available (http://appy-risk.org). WCC, white cell count; CRP, C‐reactive protein; AIRS, Appendicitis Inflammatory Response Score; AAS, Adult Appendicitis Score. Important differences between men and women
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- 2019
7. Appendicitis risk prediction models in children presenting with right iliac fossa pain (RIFT study): a prospective, multicentre validation study
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Nepogodiev, Dmitri, primary, Wilkin, Richard JW, additional, Bradshaw, Catherine J, additional, Skerritt, Clare, additional, Ball, Alasdair, additional, Moni-Nwinia, Waaka, additional, Blanco-Colino, Ruth, additional, Chauhan, Priyesh, additional, Drake, Thomas M, additional, Frasson, Matteo, additional, Gee, Oliver, additional, Glasbey, James C, additional, Matthews, Jacob H, additional, Morley, Gabriella L, additional, Naumann, David N, additional, Pata, Francesco, additional, Soares, Antonio S, additional, Bhangu, Aneel, additional, Abbas, SH, additional, Abdelgadir, AM, additional, Abdelrahman, A, additional, Abdelrahman, M, additional, Abdelwahed, A, additional, Abou El Ella, Y, additional, Abulafi, M, additional, Acharya, A, additional, Adam, ME, additional, Adams, RE, additional, Adegbola, SO, additional, Adimonye, A, additional, Adnan, M, additional, Afshar, S, additional, Ahad, A, additional, Ahel, J, additional, Ahern, DP, additional, Ahmad Asmadi, A, additional, Ahmed, B, additional, Ahmed, G, additional, Ahmed, OS, additional, Ahmed, S, additional, Akbari, K, additional, Akinsola, O, additional, Al-Khyatt, W, additional, Al-Sarireh, B, additional, Al-Sheikh, M, additional, Alani, M, additional, Alexander, R, additional, Alhammali, T, additional, Ali, M, additional, Aljorfi, A, additional, Allen, M, additional, Allington, J, additional, Alshafei, A, additional, Amarasinghe, R, additional, Amayo, A, additional, Amin, V, additional, Amuthalingam, Thuva, additional, Anandan, L, additional, Anderson, O, additional, Andreani, SM, additional, Andrews, B, additional, Ang, A, additional, Aravind, B, additional, Archer, JE, additional, Aremu, MA, additional, Arunachalam, S, additional, Aruparayil, N, additional, Ashmore, DL, additional, Ashour, O, additional, Ashraf, N, additional, Assaf, N, additional, Avalapati, H, additional, Awokoya, OO, additional, Ayube-Brown, J, additional, Badenoch, T, additional, Bagga, R, additional, Baginski, A, additional, Bailey, S, 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Sandu, L, additional, Sarmah, P, additional, Sarveswaran, J, additional, Saunders, SMF, additional, Savill, A, additional, Savioli, F, additional, Schuster Bruce, JR, additional, Sebastian, JF, additional, Seddon, TC, additional, Seneviratne, N, additional, Seth, M, additional, Setshwaelo, T, additional, Sezen, E, additional, Sgardelis, P, additional, Sgrò, A, additional, Shah, C, additional, Shah, J, additional, Shah, K, additional, Shah, SM, additional, Shakoor, Z, additional, Shalaby, MS, additional, Shanmuganathan, V, additional, Shanmugarajah, K, additional, Sharma, A, additional, Sharma, P, additional, Sharp, OL, additional, Shepherd, JA, additional, Sherif, MA, additional, Shet, S, additional, Shingler, G, additional, Shiwani, MH, additional, Shreshta, D, additional, Sian, T, additional, Siddiqui, MN, additional, Siddiqui, ZA, additional, Siggens, KL, additional, Sihra, N, additional, Silva, I, additional, Simioni, A, additional, Simmonds, LFC, additional, Simpson, DJ, additional, Singh, A, additional, Singh, S, additional, Singhal, T, additional, Sivaloganathan, P, additional, Sloan, K, additional, Smallcombe, N, additional, Smart, CJ, additional, Smart, Neil J, additional, Smith, R, additional, Smoker, H, additional, Solinas, L, additional, Souter, JEH, additional, Springate, EL, additional, Stephens, GF, additional, Stevenson, R, additional, Stewart, DJ, additional, Stoica, I, additional, Strachan, E, additional, Stubbs, BM, additional, Stupalkowska, W, additional, Suliman, A, additional, Sultana, A, additional, Sunter, H, additional, Suriyakumar, S, additional, Symons, NRA, additional, Szentpali, K, additional, Szucs, A, additional, Tabain, V, additional, Tague, LE, additional, Tailor, K, additional, Tan, CY, additional, Tan, S, additional, Tang, AM, additional, Tarazi, M, additional, Tay, YH, additional, Tayeh, S, additional, Taylor, M, additional, Taylor, NS, additional, Taze, D, additional, Teasdale, E, additional, Thakral, N, additional, Thava, B, additional, Thavanesan, N, additional, Thaventhiran, AJ, additional, Theodoropoulou, K, additional, Thomas, AT, additional, Thomas, L, additional, Thompson, DB, additional, Thompson, R, additional, Thoukididou, SN, additional, Tiboni, SG, additional, Tiedt, LA, additional, Ting, N, additional, Tinsley, BJ, additional, Tognarelli, JM, additional, Torkington, J, additional, Torrance, A, additional, Townsend, DC, additional, Tozer, PJ, additional, Trail, M, additional, Trew, F, additional, Tudyka, V, additional, Tullie, L, additional, Turnbull, A, additional, Turner, EJ, additional, Twum-Barima, CS, additional, Tyler, Robert, additional, Vakis, S, additional, Valle, A La, additional, Van Boxel, GI, additional, Vance-Daniel, J, additional, Varcada, M, additional, Varma, N, additional, Vaughan, EM, additional, Velchuru, VR, additional, Velho, R, additional, Venkatasubramaniam, AK, additional, Venn, ML, additional, Vijay, V, additional, Vinnicombe, Z, additional, Vitish-Sharma, P, additional, Wagener, S, additional, Waite, K, additional, Walters, KJ, additional, Walters, U, additional, Wardle, BG, additional, Wardle, SD, additional, Warusavitarne, J, additional, Watfah, J, additional, Watson, N, additional, Wauchope, J, additional, Weatherburn, LW, additional, Weegenaar, CR, additional, Welsh, S, additional, Wheatstone, S, additional, Whewell, HE, additional, Whitehouse, P, additional, Whiteman, E, additional, Whittaker, L, additional, Wijesundera, K, additional, Wilkinson, D, additional, Williams, GL, additional, Williams, M, additional, Williams, R, additional, Williams, S, additional, Wilson, EJ, additional, Wilson, MSJ, additional, Winter, DC, additional, Winter, G, additional, Wolff, J, additional, Wong, A, additional, Wong, CLL, additional, Wong, SY, additional, Wood, CS, additional, Woodrow, C, additional, Woodward, A, additional, Woodward, B, additional, Wright, E, additional, Wright, HL, additional, Wu, F, additional, Yalamarthi, S, additional, Yang, P, additional, Yardimci, E, additional, Yasin, T, additional, Yen, SK, additional, Yoganathan, S, additional, Yoong, S, additional, Youssef, H, additional, Yow, LPS, additional, Zaborowski, A, additional, Zadi, AZ, additional, Zarka, ZA, additional, Zarog, MA, additional, and Zhang, AY, additional
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- 2020
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8. Case-control vaccine effectiveness studies: Preparation, design, and enrollment of cases and controls.
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Verani, JR, Baqui, AH, Broome, CV, Cherian, T, Cohen, C, Farrar, JL, Feikin, DR, Groome, MJ, Hajjeh, RA, Johnson, HL, Madhi, SA, Mulholland, K, O'Brien, KL, Parashar, UD, Patel, MM, Rodrigues, LC, Santosham, M, Scott, JA, Smith, PG, Sommerfelt, H, Tate, JE, Victor, JC, Whitney, CG, Zaidi, AK, Zell, ER, Verani, JR, Baqui, AH, Broome, CV, Cherian, T, Cohen, C, Farrar, JL, Feikin, DR, Groome, MJ, Hajjeh, RA, Johnson, HL, Madhi, SA, Mulholland, K, O'Brien, KL, Parashar, UD, Patel, MM, Rodrigues, LC, Santosham, M, Scott, JA, Smith, PG, Sommerfelt, H, Tate, JE, Victor, JC, Whitney, CG, Zaidi, AK, and Zell, ER
- Abstract
Case-control studies are commonly used to evaluate effectiveness of licensed vaccines after deployment in public health programs. Such studies can provide policy-relevant data on vaccine performance under 'real world' conditions, contributing to the evidence base to support and sustain introduction of new vaccines. However, case-control studies do not measure the impact of vaccine introduction on disease at a population level, and are subject to bias and confounding, which may lead to inaccurate results that can misinform policy decisions. In 2012, a group of experts met to review recent experience with case-control studies evaluating the effectiveness of several vaccines; here we summarize the recommendations of that group regarding best practices for planning, design and enrollment of cases and controls. Rigorous planning and preparation should focus on understanding the study context including healthcare-seeking and vaccination practices. Case-control vaccine effectiveness studies are best carried out soon after vaccine introduction because high coverage creates strong potential for confounding. Endpoints specific to the vaccine target are preferable to non-specific clinical syndromes since the proportion of non-specific outcomes preventable through vaccination may vary over time and place, leading to potentially confusing results. Controls should be representative of the source population from which cases arise, and are generally recruited from the community or health facilities where cases are enrolled. Matching of controls to cases for potential confounding factors is commonly used, although should be reserved for a limited number of key variables believed to be linked to both vaccination and disease. Case-control vaccine effectiveness studies can provide information useful to guide policy decisions and vaccine development, however rigorous preparation and design is essential.
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- 2017
9. Case-control vaccine effectiveness studies: Data collection, analysis and reporting results.
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Verani, JR, Baqui, AH, Broome, CV, Cherian, T, Cohen, C, Farrar, JL, Feikin, DR, Groome, MJ, Hajjeh, RA, Johnson, HL, Madhi, SA, Mulholland, K, O'Brien, KL, Parashar, UD, Patel, MM, Rodrigues, LC, Santosham, M, Scott, JA, Smith, PG, Sommerfelt, H, Tate, JE, Victor, JC, Whitney, CG, Zaidi, AK, Zell, ER, Verani, JR, Baqui, AH, Broome, CV, Cherian, T, Cohen, C, Farrar, JL, Feikin, DR, Groome, MJ, Hajjeh, RA, Johnson, HL, Madhi, SA, Mulholland, K, O'Brien, KL, Parashar, UD, Patel, MM, Rodrigues, LC, Santosham, M, Scott, JA, Smith, PG, Sommerfelt, H, Tate, JE, Victor, JC, Whitney, CG, Zaidi, AK, and Zell, ER
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The case-control methodology is frequently used to evaluate vaccine effectiveness post-licensure. The results of such studies provide important insight into the level of protection afforded by vaccines in a 'real world' context, and are commonly used to guide vaccine policy decisions. However, the potential for bias and confounding are important limitations to this method, and the results of a poorly conducted or incorrectly interpreted case-control study can mislead policies. In 2012, a group of experts met to review recent experience with case-control studies evaluating vaccine effectiveness; we summarize the recommendations of that group regarding best practices for data collection, analysis, and presentation of the results of case-control vaccine effectiveness studies. Vaccination status is the primary exposure of interest, but can be challenging to assess accurately and with minimal bias. Investigators should understand factors associated with vaccination as well as the availability of documented vaccination status in the study context; case-control studies may not be a valid method for evaluating vaccine effectiveness in settings where many children lack a documented immunization history. To avoid bias, it is essential to use the same methods and effort gathering vaccination data from cases and controls. Variables that may confound the association between illness and vaccination are also important to capture as completely as possible, and where relevant, adjust for in the analysis according to the analytic plan. In presenting results from case-control vaccine effectiveness studies, investigators should describe enrollment among eligible cases and controls as well as the proportion with no documented vaccine history. Emphasis should be placed on confidence intervals, rather than point estimates, of vaccine effectiveness. Case-control studies are a useful approach for evaluating vaccine effectiveness; however careful attention must be paid to the collection, ana
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- 2017
10. The Influence and Compatibility of Vegetable Oils and other Additives on Release of Ketoprofen from Transdermal Films
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Patel, HR, Patel, RB, Patel, GN, and Patel, MM
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The vegetable oils used as skin permeation enhancers were selected on the basis of compatibility studies data. A total of eight monolithic systems were prepared by using different concentrations of drug-polymers-permeation enhancers. The permeation parameters, flux, permeability coefficient, enhancement ratio and diffusion rate constants were determined. The maximum flux of 9.08 x 10-2 mg/cm2.h was observed with hydroxy propyl methyl cellulose monolithic system containing 30% w/w olive oil. Further improvement of flux was observed, when 30% w/w olive oil was applied directly onto the skin prior to the studies. The release was sustained up to 24 hours with zero-order kinetics and diffusion controlled mechanism. The 30% w/w olive oil formulation showed promising results with in vivo results showing significant analgesic and anti-inflammatory activities (P < 0.01) with no hypersensitivity reactions. Stability studies and scanning electron microscopy studies were also conducted. Keywords: Vegetable oils, flux, ketoprofen, polymersEast and Central African Journal of Pharmaceutical Sciences Vol. 13 (2010) 19-24
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- 2014
11. Direct and indirect effects of rotavirus vaccination: Comparing predictions from transmission dynamic models
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Pitzer, VE, Atkins, KE, de Blasio, BF, van Effelterre, T, Atchison, CJ, Harris, JP, Shim, E, Galvani, AP, Edmunds, WJ, Viboud, C, Patel, MM, Grenfell, BT, Parashar, UD, Lopman, BA, Pitzer, VE, Atkins, KE, de Blasio, BF, van Effelterre, T, Atchison, CJ, Harris, JP, Shim, E, Galvani, AP, Edmunds, WJ, Viboud, C, Patel, MM, Grenfell, BT, Parashar, UD, and Lopman, BA
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Early observations from countries that have introduced rotavirus vaccination suggest that there may be indirect protection for unvaccinated individuals, but it is unclear whether these benefits will extend to the long term. Transmission dynamic models have attempted to quantify the indirect protection that might be expected from rotavirus vaccination in developed countries, but results have varied. To better understand the magnitude and sources of variability in model projections, we undertook a comparative analysis of transmission dynamic models for rotavirus. We fit five models to reported rotavirus gastroenteritis (RVGE) data from England and Wales, and evaluated outcomes for short- and long-term vaccination effects. All of our models reproduced the important features of rotavirus epidemics in England and Wales. Models predicted that during the initial year after vaccine introduction, incidence of severe RVGE would be reduced 1.8-2.9 times more than expected from the direct effects of the vaccine alone (28-50% at 90% coverage), but over a 5-year period following vaccine introduction severe RVGE would be reduced only by 1.1-1.7 times more than expected from the direct effects (54-90% at 90% coverage). Projections for the long-term reduction of severe RVGE ranged from a 55% reduction at full coverage to elimination with at least 80% coverage. Our models predicted short-term reductions in the incidence of RVGE that exceeded estimates of the direct effects, consistent with observations from the United States and other countries. Some of the models predicted that the short-term indirect benefits may be offset by a partial shifting of the burden of RVGE to older unvaccinated individuals. Nonetheless, even when such a shift occurs, the overall reduction in severe RVGE is considerable. Discrepancies among model predictions reflect uncertainties about age variation in the risk and reporting of RVGE, and the duration of natural and vaccine-induced immunity, highlighting im
- Published
- 2012
12. Osteometric Dimensions of the Laminas of the Spine
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Patel, MM, primary and Singel, TC, additional
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- 2011
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13. Optimization of luminescent assay for screening of cyclin-dependent kinase 2 inhibitors
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Suthar, MP, primary and Patel, MM, additional
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- 2010
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14. Mechanisms of potentiation of Angiotensin II-induced contractile response of isolated rat aorta by hydrogen peroxide and tert-butyryl hydroperoxide
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Patel, RJ, primary, Patel, PD, additional, Patel, MM, additional, Patel, NJ, additional, and Thyagarajan, B, additional
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- 2009
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15. Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique
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Patel, DM, primary and Patel, MM, additional
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- 2008
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16. Utility of scrape smear in diagnosis ofPaget′s diseasesof breast - a case report
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Patel, MM, primary, Modi, JP, additional, and Patel, TS, additional
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- 2007
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17. High performance thin layer chromatographic method for estimation of linezolid in tablets
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Patel, SA, primary, Patel, PU, additional, Patel, NJ, additional, Patel, MM, additional, and Bangoriya, UV, additional
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- 2007
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18. Fast dissolving Valdecoxib tablets containing solid dispersion of Valdecoxib
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Patel, DM, primary and Patel, MM, additional
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- 2006
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19. Simultaneous spectrophotometric estimation of Ciprofloxacin and Ornidazole in tablets
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Patel, SA, primary, Patel, NM, additional, and Patel, MM, additional
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- 2006
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20. Studies on formulation andin vitrodissolution of Embelin tablets
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Pundarikakshudu, K, primary, Momin, Munira, additional, Patel, MM, additional, and Patel, RK, additional
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- 2006
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21. Spectrophotometric methods for the estimation of Cephalexin in tablet dosage forms
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Patel, SA, primary, Patel, NM, additional, and Patel, MM, additional
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- 2006
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22. Visible spectrophotometric methods for the estimation of metoclopramide hydrochloride in tablets
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Patel, SA, primary, Patel, CN, additional, and Patel, MM, additional
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- 2006
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23. Spectrophotometric estimation of cefotaxime and ceftriaxone in pharmaceutical dosage forms
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Patel, SA, primary, Patel, NM, additional, and Patel, MM, additional
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- 2006
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24. Alterations in plasma lipid profile patterns in head and neck cancer and oral precancerous conditions
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Patel, PrabhudasS, primary, Shah, MH, additional, Jha, FP, additional, Raval, GN, additional, Rawal, RM, additional, Patel, MM, additional, Patel, JB, additional, and Patel, DD, additional
- Published
- 2004
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25. Trends in intussusception hospitalizations among US infants before and after implementation of the rotavirus vaccination program, 2000-2009.
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Yen C, Tate JE, Steiner CA, Cortese MM, Patel MM, Parashar UD, Yen, Catherine, Tate, Jacqueline E, Steiner, Claudia A, Cortese, Margaret M, Patel, Manish M, and Parashar, Umesh D
- Abstract
Background: Although US data have not documented an intussusception risk with current rotavirus vaccines, international data indicate a possible low risk, primarily after the first dose.Methods: Among infants in 26 US states comprising 75% of the birth cohort, we examined age-specific trends in population-level intussusception hospitalization rates before (2000-2005) and after (2007-2009) rotavirus vaccine introduction.Results: Compared with 2000-2005 (35.3 per 100,000), the rate was greater in 2007 (39.0 per 100,000; rate ratio [RR], 1.10; 95% confidence interval [CI], 1.04-1.18), similar in 2008 (33.4 per 100,000; RR, 0.95; 95% CI, .89-1.01), and lower in 2009 (32.9 per 100,000; RR, 0.93; 95% CI, .87-.99). Among infants aged 8-11 weeks, compared with 2000-2005 (6.9 per 100,000), a small, significant increase was observed in each of 2007 (11.4 per 100,000; RR, 1.64; 95% CI, 1.08-2.50), 2008 (12.2 per 100,000; RR, 1.76; 95% CI, 1.17-2.65), and 2009 (11.0 per 100,000; RR, 1.59; 95% CI, 1.04-2.44).Conclusions: Following rotavirus vaccine introduction, a small increase in intussusception rates was seen among US infants aged 8-11 weeks, to whom most first doses of vaccine are given; no sustained population-level change in overall rates was observed. [ABSTRACT FROM AUTHOR]- Published
- 2012
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26. Factors associated with bowel resection among infants with intussusception in the United States.
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Johnson B, Gargiullo P, Murphy TV, Parashar UD, and Patel MM
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- 2012
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27. Monovalent Rotavirus Vaccine Provides Protection Against an Emerging Fully Heterotypic G9P[4] Rotavirus Strain in Mexico.
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Yen C, Figueroa JR, Uribe ES, Carmen-Hernández LD, Tate JE, Parashar UD, Patel MM, and Richardson López-Collado V
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After the introduction of monovalent rotavirus vaccine (RV1) in Mexico in 2006-2007, diarrhea mortality and morbidity declined substantially among Mexican children under 5 years of age. In January 2010, surveillance identified the emergence of a novel G9P[4] rotavirus strain nationwide. We conducted a case-control study to assess the field effectiveness of RV1 against severe rotavirus gastroenteritis caused by this unusual strain and to determine whether the G9P[4] emergence was related to vaccine failure or failure to vaccinate. RV1 was 94% effective (95% confidence interval, 16%-100%) against G9P[4] rotavirus-related hospitalization, indicating that its emergence was likely unrelated to vaccine pressure. [ABSTRACT FROM AUTHOR]
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- 2011
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28. Understanding common statistical methods, Part I: descriptive methods, probability, and continuous data.
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Skinner CG, Patel MM, Thomas JD, Miller MA, Skinner, Carl G, Patel, Manish M, Thomas, Jerry D, and Miller, Michael A
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Statistical methods are pervasive in medical research and general medical literature. Understanding general statistical concepts will enhance our ability to critically appraise the current literature and ultimately improve the delivery of patient care. This article intends to provide an overview of the common statistical methods relevant to medicine. [ABSTRACT FROM AUTHOR]
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- 2011
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29. Sociodemographic and dietary risk factors for natural infant intussusception in the United States.
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Johnson B, Gargiullo P, Murphy TV, Parashar UD, and Patel MM
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- 2010
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30. Ambient metals, elemental carbon, and wheeze and cough in New York City children through 24 months of age.
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Patel MM, Hoepner L, Garfinkel R, Chillrud S, Reyes A, Quinn JW, Perera F, Miller RL, Patel, Molini M, Hoepner, Lori, Garfinkel, Robin, Chillrud, Steven, Reyes, Andria, Quinn, James W, Perera, Frederica, and Miller, Rachel L
- Abstract
Rationale: The effects of exposure to specific components of ambient fine particulate matter (PM(2.5)), including metals and elemental carbon (EC), have not been fully characterized in young children.Objectives: To compare temporal associations among PM(2.5); individual metal constituents of ambient PM(2.5), including nickel (Ni), vanadium (V), and zinc (Zn); and EC and longitudinal reports of respiratory symptoms through 24 months of age.Methods: Study participants were selected from the Columbia Center for Children's Environmental Health birth cohort recruited in New York City between 1998 and 2006. Respiratory symptom data were collected by questionnaire every 3 months through 24 months of age. Ambient pollutant data were obtained from state-operated stationary monitoring sites located within the study area. For each subject, 3-month average inverse-distance weighted concentrations of Ni, V, Zn, EC, and PM(2.5) were calculated for each symptom-reporting period based on the questionnaire date and the preceding 3 months. Associations between pollutants and symptoms were characterized using generalized additive mixed effects models, adjusting for sex, ethnicity, environmental tobacco smoke exposure, and calendar time.Measurements and Main Results: Increases in ambient Ni and V concentrations were associated significantly with increased probability of wheeze. Increases in EC were associated significantly with cough during the cold/flu season. Total PM(2.5) was not associated with wheeze or cough.Conclusions: These results suggest that exposure to ambient metals and EC from heating oil and/or traffic at levels characteristic of urban environments may be associated with respiratory symptoms among very young children. [ABSTRACT FROM AUTHOR]- Published
- 2009
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31. Air pollution and childhood asthma: recent advances and future directions.
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Patel MM, Miller RL, Patel, Molini M, and Miller, Rachel L
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- 2009
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32. Getting into the brain: approaches to enhance brain drug delivery.
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Patel MM, Goyal BR, Bhadada SV, Bhatt JS, Amin AF, Patel, Mayur M, Goyal, Bhoomika R, Bhadada, Shraddha V, Bhatt, Jay S, and Amin, Avani F
- Abstract
Being the most delicate organ of the body, the brain is protected against potentially toxic substances by the blood-brain barrier (BBB), which restricts the entry of most pharmaceuticals into the brain. The developmental process for new drugs for the treatment of CNS disorders has not kept pace with progress in molecular neurosciences because most of the new drugs discovered are unable to cross the BBB. The clinical failure of CNS drug delivery may be attributed largely to a lack of appropriate drug delivery systems. Localized and controlled delivery of drugs at their desired site of action is preferred because it reduces toxicity and increases treatment efficiency. The present review provides an insight into some of the recent advances made in the field of brain drug delivery.The various strategies that have been explored to increase drug delivery into the brain include (i) chemical delivery systems, such as lipid-mediated transport, the prodrug approach and the lock-in system; (ii) biological delivery systems, in which pharmaceuticals are re-engineered to cross the BBB via specific endogenous transporters localized within the brain capillary endothelium; (iii) disruption of the BBB, for example by modification of tight junctions, which causes a controlled and transient increase in the permeability of brain capillaries; (iv) the use of molecular Trojan horses, such as peptidomimetic monoclonal antibodies to transport large molecules (e.g. antibodies, recombinant proteins, nonviral gene medicines or RNA interference drugs) across the BBB; and (v) particulate drug carrier systems. Receptor-mediated transport systems exist for certain endogenous peptides, such as insulin and transferrin, enabling these molecules to cross the BBB in vivo.The use of polymers for local drug delivery has greatly expanded the spectrum of drugs available for the treatment of brain diseases, such as malignant tumours and Alzheimer's disease. In addition, various drug delivery systems (e.g. liposomes, microspheres, nanoparticles, nanogels and bionanocapsules) have been used to enhance drug delivery to the brain. Recently, microchips and biodegradable polymers have become important in brain tumour therapy.The intense search for alternative routes of drug delivery (e.g. intranasal drug delivery, convection-enhanced diffusion and intrathecal/intraventricular drug delivery systems) has been driven by the need to overcome the physiological barriers of the brain and to achieve high drug concentrations within the brain. For more than 30 years, considerable efforts have been made to enhance the delivery of therapeutic molecules across the vascular barriers of the CNS. The current challenge is to develop drug delivery strategies that will allow the passage of drug molecules through the BBB in a safe and effective manner. [ABSTRACT FROM AUTHOR]
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- 2009
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33. Burnout amongst poison specialists
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Herrington, LH, Geller, RJ, and Patel, MM
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Poison control centers -- Officials and employees ,Medical personnel -- Psychological aspects ,Burn out (Psychology) -- Causes of ,Environmental issues ,Health ,Pharmaceuticals and cosmetics industries - Abstract
Background: One factor influencing employee turnover is burnout. Burnout is described as a syndrome of increased emotional exhaustion (EE), increased depersonalization (DP), and reduced personal accomplishment (PA). The Maslach Burnout Inventory-Human Services Survey (MBI-HSS) is a tool designed to assess the degree of burnout. The purpose of this study is to determine the degree of burnout amongst poison specialists. Methods: The MBI-HSS and a demographic questionnaire were mailed to 1,114 poison specialists in the US and Canada. Analyses included two-sample t-tests and multi-variate linear regression. Results: 336 completed surveys were returned (30%). Respondents were 59% RNs, 29% RPh, 2% MD, and 10% non-RN/non-RPh. Average age was 41 years; 76% were female. Poison specialists had lower EE scores (p < 0.0001) and higher PA scores (p < 0.0001) than the 'medical' normative score, indicating lower levels of burnout. Perceived fair & manageable workload and positive managerial/administrative support were negatively associated with EE (p < .0001 each). Individuals who perceived their jobs as stressful were likely to have greater DP (p < .0019). Poison specialists reporting more emotional satisfaction had lower EE and DP, and higher PA (p < .0003,.0001,.0001, respectively). Conclusions: The cost of training new poison specialists is high. The non-monetary cost of losing experienced staff is even higher. Managerial and administrative support, an equitable distribution of workload, and assistance in achieving professional satisfaction may impact the incidence and degree of burnout among poison specialists., Herrington LH, Geller RJ, Patel MM. Georgia Poison Center, Emory University School of Medicine, Atlanta [...]
- Published
- 2002
34. Recognition of illness associated with covert chemical releases.
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Patel MM, Schier JG, and Belson MG
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- 2006
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35. Persistent hiccups associated with intravenous corticosteroid therapy.
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Hung Y, Miller MA, and Patel MM
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- 2003
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36. Shedding new light on the 'safe' club drug: methylenedioxymethamphetamine (Ecstasy)-related fatalities.
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Patel MM, Wright DW, Ratcliff JJ, and Miller MA
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- 2004
37. Evaluation of Left Ventricular Function by Systolic Time Intervals in Patients with Calcified Mitral Annulus
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S. Thanks, Patel Mm, O. Zoneraich, and S. Zoneraich
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medicine.medical_specialty ,Systolic Murmurs ,Mitral regurgitation ,Heart disease ,business.industry ,education ,medicine.disease ,humanities ,Systolic time intervals ,Internal medicine ,cardiovascular system ,medicine ,Cardiology ,Mitral Valve Annulus ,In patient ,cardiovascular diseases ,Mitral annulus ,business ,Calcification - Abstract
Mitral ring calcification is the commonest abnormality found in elderly patients with systolic murmurs (1, 2). Extensive calcification of the mitral valve annulus which may produce variable degrees of mitral regurgitation can be strongly suspected in individuals over 50 years of age with systolic apical murmurs and no history of previous rheumatic heart disease. Calcified mitral annulus (CMA) is found in about 10% of autopsies in patients over age 50.
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- 1980
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38. The emission spectrum of bismuth bromide (BiBr)-'A' system
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Sankaranarayanan, S, Patel, MM, and Narayanan, PS
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Physics - Abstract
The emission spectrum of bismuth monobromide has been investigated and a vibrational analysis of the A→X system has been made. About 286 bands were recorded in the region λλ 4595–6063 and the isotope effect due to Br79 and Br81 was observed in about 87 bands. A value of 2·74 ev. for the dissociation energy of the excited state has been obtained and arguments have been given to show that the dissociation products in the excited state are Bi(4S3/2) and Br(2P3/2) and that those of the ground state are most probably Bi (4S3/2) and Br (2P1/2) atoms.
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- 1962
39. Vibrational analysis of the (B2P{cyrillic}→X2P{cyrillic}) system of NS
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Patel, MM
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Physics - Abstract
A few red degraded bands attributable to NS have been reported earlier by Fowler and Barker, Dressler and Barrow et al, and they occur in the same region (2300 to 2700 Å) as the bands of the known systems (C2∑+-X2P{cyrillic}) and (A2Δ-X2P{cyrillic}). Measurements made on the heads of some of these weak bands led Barrow et al. to believe that these bands may form a system analogous to the β-system of NO and be due to a2P{cyrillic}-2P{cyrillic} transition. The spectrum of NS has now been studied in a little more detail by means of an uncondensed discharge through dry nitrogen and sulphur vapour in the presence of argon and thirty three bands belonging to this system have been recorded in the region 2280 to 2760 Å. It has been found possible to represent the band heads by means of the equation {Mathematical expression}. Taking the lower state doublet interval as 223 cm-1, it is shown that the separation in the upper state is 94 cm-1. The ratio of the force constants in the upper and the ground states is found to be 0·39 and is nearly the same as that in the β-system of NO (0·30). The present vibrational analysis therefore supports the view that these new red degraded bands of NS arise from a (B2P{cyrillic}→X2P{cyrillic}) transition and the observed intensity distribution in the form of a wide parabola is also in qualitative agreement with what is expected from the moderately large Δ re (∼0·12Å) value.
- Published
- 1963
40. The emission spectrum of bismuth monofluoride BiF—‘A’ system
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Sankaranarayanan, S, Narayanan, PS, and Patel, MM
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Physics - Abstract
The observation of (A-X) system of BiF has been extended up to λ 5316 and twenty new bands belonging to this system have been recorded. The band heads could be represented by the following equation: {Mathematical expression} Seven other faint bands in the region λ 5316-5492 have also been reported, which, however, could not be classified. By our analysis of the present data and from known thermochemical data it has been deduced that the ground state dissociation energy is, in all probability, around 20000 cm.-1 (∼2·5 ev.) and that the dissociation products are the normal Bi and F atoms. The dissociation energy of the upper state and the correlation rules have been used to show that the dissociation products in the upper state are very likely to be Bi atom in the excited state2D3/2 and F atom in its ground state (2P3/2).
- Published
- 1964
41. Preparation and Evaluation of Inclusion Complex of the Lipid Lowering Drug Lovastatin with ?-Cyclodextrin
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Patel, RP, primary and Patel, MM, primary
- Published
- 1970
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42. Removing the age restrictions for rotavirus vaccination: a benefit-risk modeling analysis.
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Patel MM, Clark AD, Sanderson CF, Tate J, Parashar UD, Patel, Manish M, Clark, Andrew D, Sanderson, Colin F B, Tate, Jacqueline, and Parashar, Umesh D
- Abstract
Background: To minimize potential risk of intussusception, the World Health Organization (WHO) recommended in 2009 that rotavirus immunization should be initiated by age 15 weeks and completed before 32 weeks. These restrictions could adversely impact vaccination coverage and thereby its health impact, particularly in developing countries where delays in vaccination often occur.Methods and Findings: We conducted a modeling study to estimate the number of rotavirus deaths prevented and the number of intussusception deaths caused by vaccination when administered on the restricted schedule versus an unrestricted schedule whereby rotavirus vaccine would be administered with DTP vaccine up to age 3 years. Countries were grouped on the basis of child mortality rates, using WHO data. Inputs were estimates of WHO rotavirus mortality by week of age from a recent study, intussusception mortality based on a literature review, predicted vaccination rates by week of age from USAID Demographic and Health Surveys, the United Nations Children's Fund (UNICEF) Multiple Indicator Cluster Surveys (MICS), and WHO-UNICEF 2010 country-specific coverage estimates, and published estimates of vaccine efficacy and vaccine-associated intussusception risk. On the basis of the error estimates and distributions for model inputs, we conducted 2,000 simulations to obtain median estimates of deaths averted and caused as well as the uncertainty ranges, defined as the 5th-95th percentile, to provide an indication of the uncertainty in the estimates. We estimated that in low and low-middle income countries a restricted schedule would prevent 155,800 rotavirus deaths (5th-95th centiles, 83,300-217,700) while causing potentially 253 intussusception deaths (76-689). In contrast, vaccination without age restrictions would prevent 203,000 rotavirus deaths (102,000-281,500) while potentially causing 547 intussusception deaths (237-1,160). Thus, removing the age restrictions would avert an additional 47,200 rotavirus deaths (18,700-63,700) and cause an additional 294 (161-471) intussusception deaths, for an incremental benefit-risk ratio of 154 deaths averted for every death caused by vaccine. These extra deaths prevented under an unrestricted schedule reflect vaccination of an additional 21%-25% children, beyond the 63%-73% of the children who would be vaccinated under the restricted schedule. Importantly, these estimates err on the side of safety in that they assume high vaccine-associated risk of intussusception and do not account for potential herd immunity or non-fatal outcomes.Conclusions: Our analysis suggests that in low- and middle-income countries the additional lives saved by removing age restrictions for rotavirus vaccination would far outnumber the potential excess vaccine-associated intussusception deaths. Please see later in the article for the Editors' Summary. [ABSTRACT FROM AUTHOR]- Published
- 2012
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43. Clinical practice guideline: tonsillectomy in children.
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Baugh RF, Archer SM, Mitchell RB, Rosenfeld RM, Amin R, Burns JJ, Darrow DH, Giordano T, Litman RS, Li KK, Mannix ME, Schwartz RH, Setzen G, Wald ER, Wall E, Sandberg G, Patel MM, and American Academy of Otolaryngology-Head and Neck Surgery Foundation
- Published
- 2011
- Full Text
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44. Adoption of rotavirus vaccination by pediatricians and family medicine physicians in the United States.
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Kempe A, Patel MM, Daley MF, Crane LA, Beaty B, Stokley S, Barrow J, Babbel C, Dickinson LM, Tempte JL, and Parashar UD
- Abstract
Objectives: The goals were to assess, among pediatricians and family medicine physicians, (1) rates of offering the vaccine in their office; (2) knowledge of Advisory Committee on Immunization Practices recommendations; (3) barriers to use; and (4) factors associated with offering the vaccine. Methods: Surveys of pediatricians and family medicine physicians were conducted in August to October 2007. Results: Response rates were 84% for pediatricians and 79% for family medicine physicians (N = 623). Proportions routinely offering the vaccine were 85% of pediatricians and 45% of family medicine physicians (P < .0001); 70% of pediatricians and 22% of family medicine strongly recommended the vaccine (P < .0001). Sixty-two percent of pediatricians and 32% of family medicine physicians (P < .0001) knew the age by which all 3 doses should be completed. Definite barriers to vaccine use included reported lack of coverage by insurance companies (family medicine physicians: 22%; pediatricians: 19%; not significant), costs of purchasing vaccine (family medicine physicians: 22%; pediatricians: 17%; not significant), lack of adequate reimbursement (family medicine physicians: 18%; pediatricians: 15%; not significant), concerns about safety (family medicine physicians: 25%; pediatricians: 9%; P < .0001), and concerns about adding another vaccine to the schedule (family medicine physicians: 22%; pediatricians: 5%; P < .0001). Conclusions: Rates of offering the new rotavirus vaccine are high among pediatricians but <50% among family medicine physicians. Both specialties identified financial barriers to use of the vaccine, but family medicine physicians had significantly more concerns about safety and about adding another vaccine to the vaccination schedule. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
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45. Strategies for recognizing acute chemical-associated foodborne illness.
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Schier JG, Rogers HS, Patel MM, Rubin CA, Belson MG, Schier, Joshua G, Rogers, Helen Schurz, Patel, Manish M, Rubin, Carol A, and Belson, Martin G
- Abstract
The U.S. food supply is vulnerable to contamination with chemicals and toxins. Public health officials and clinicians may misdiagnose patients with acute chemical-associated foodborne illness (CAFI) due to unfamiliarity with chemical illness, increased familiarity with infectious foodborne illness, nonspecific presentation of most foodborne chemical poisoning, lack of readily available analytic methodologies to detect chemicals, and lack of education on how to develop a differential diagnosis for CAFI. This article will review the unique features of CAFI in the acute setting, address important questions to help differentiate CAFI from other foodborne illness, discuss laboratory features of CAFI, and provide health officials and clinicians with a clinical symptom-based approach to assist with proper identification and differentiation of acute CAFI. [ABSTRACT FROM AUTHOR]
- Published
- 2006
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46. Diuretics-Induced Acute Pancreatitis: Case Series with a Review of the Literature.
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Patel DM, Patel MM, Patel LB, Patel VB, Patel MV, and Patel DK
- Abstract
Background: Although diuretic-induced Acute Pancreatitis (AP) cases are typically mild to moderate, severe and potentially fatal occurrences can arise. Case Series and Literature Review: We have, herein, presented a series of diuretic-induced AP cases from March 2018 to February 2024 of a 54-year-old woman treated with chlorthalidone, a 45-year-old male treated with hydrochlorothiazide, and a 48-year-old male treated with frusemide. The literature search has identified 26 cases published to date, 10 from frusemide and 16 from thiazide diuretics. The Naranjo adverse reaction probability scale has categorized all three drugs as "probable". All cases have responded to conservative treatment and cessation of the offending drug. Various mechanisms, such as hypersensitization, ischemia, direct cytotoxic effects, hypercalcemia, and dose-dependent idiosyncrasy, have been found to lead to intrapancreatic activation of pancreatic enzymes, resulting in drug-induced AP., Conclusion: Further research into the mechanisms and genetic factors contributing to diureticinduced AP is essential for enabling early diagnosis and management of diuretic-induced AP., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
- Published
- 2024
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47. Diffusion Tensor Imaging for Characterizing Changes in Triple-Negative Breast Cancer During Neoadjuvant Systemic Therapy.
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Musall BC, Rauch DE, Mohamed RMM, Panthi B, Boge M, Candelaria RP, Chen H, Guirguis MS, Hunt KK, Huo L, Hwang KP, Korkut A, Litton JK, Moseley TW, Pashapoor S, Patel MM, Reed BJ, Scoggins ME, Son JB, Tripathy D, Valero V, Wei P, White JB, Whitman GJ, Xu Z, Yang WT, Yam C, Adrada BE, and Ma J
- Subjects
- Humans, Female, Middle Aged, Prospective Studies, Adult, Treatment Outcome, Anisotropy, Breast diagnostic imaging, Aged, ROC Curve, Reproducibility of Results, Diffusion Tensor Imaging methods, Neoadjuvant Therapy, Triple Negative Breast Neoplasms diagnostic imaging, Triple Negative Breast Neoplasms drug therapy, Triple Negative Breast Neoplasms therapy
- Abstract
Background: Assessment of treatment response in triple-negative breast cancer (TNBC) may guide individualized care for improved patient outcomes. Diffusion tensor imaging (DTI) measures tissue anisotropy and could be useful for characterizing changes in the tumors and adjacent fibroglandular tissue (FGT) of TNBC patients undergoing neoadjuvant systemic treatment (NAST)., Purpose: To evaluate the potential of DTI parameters for prediction of treatment response in TNBC patients undergoing NAST., Study Type: Prospective., Population: Eighty-six women (average age: 51 ± 11 years) with biopsy-proven clinical stage I-III TNBC who underwent NAST followed by definitive surgery. 47% of patients (40/86) had pathologic complete response (pCR)., Field Strength/sequence: 3.0 T/reduced field of view single-shot echo-planar DTI sequence., Assessment: Three MRI scans were acquired longitudinally (pre-treatment, after 2 cycles of NAST, and after 4 cycles of NAST). Eleven histogram features were extracted from DTI parameter maps of tumors, a peritumoral region (PTR), and FGT in the ipsilateral breast. DTI parameters included apparent diffusion coefficients and relative diffusion anisotropies. pCR status was determined at surgery., Statistical Tests: Longitudinal changes of DTI features were tested for discrimination of pCR using Mann-Whitney U test and area under the receiver operating characteristic curve (AUC). A P value <0.05 was considered statistically significant., Results: 47% of patients (40/86) had pCR. DTI parameters assessed after 2 and 4 cycles of NAST were significantly different between pCR and non-pCR patients when compared between tumors, PTRs, and FGTs. The median surface/average anisotropy of the PTR, measured after 2 and 4 cycles of NAST, increased in pCR patients and decreased in non-pCR patients (AUC: 0.78; 0.027 ± 0.043 vs. -0.017 ± 0.042 mm
2 /s)., Data Conclusion: Quantitative DTI features from breast tumors and the peritumoral tissue may be useful for predicting the response to NAST in TNBC., Evidence Level: 1 TECHNICAL EFFICACY: Stage 4., (© 2024 International Society for Magnetic Resonance in Medicine.)- Published
- 2024
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48. Unveiling Sex Differences in Pediatric Burns Through the World Health Organization (WHO) Global Burn Registry.
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Lewis JE, Patel MM, Lim SE, Wolf SE, and Song J
- Abstract
Introduction: Pediatric burns present a significant global health challenge, particularly in low- and middle-income countries (LMICs). Despite this burden, few studies have explored global sex-based differences in pediatric burns. This study aims to describe pediatric burn incidence, burn care facilities' capacities, and burn outcomes with a focus on sex, comparing LMICs to HICs., Methods: This study utilizes the World Health Organization's (WHO) Global Burn Registry (GBR) to analyze pediatric burn cases from 2018 to 2022, examining patient demographics, causes of burns, burn care facilities' capacities, and burn outcomes in relation to sex. Statistical analysis was done by chi-square and logistic regression., Results: It was found that female patients were less likely than males to undergo surgical treatment during their hospital stay in low-income countries (adjusted odd ratios = 0.86, 95% CI: 0.45-1.26; p = 0.168) and middle-income countries (adjusted odd ratios = 0.72, 95% Cl: 0.52-0.95; p = 0.002). Additionally, females in both low- (adjusted odd ratios = 2.23, 95% Cl: 1.12-3.53; p = 0.045) and middle-income countries (adjusted odd ratios = 1.72, 95% Cl: 1.12-2.95; p < 0.001) exhibited higher odds of discharging with disability compared to males., Conclusion: Sex-based differences persist in pediatric burn epidemiology and treatment outcomes. Addressing these differences involves sex-sensitive strategies to mitigate the burden of pediatric burns, particularly in vulnerable populations in low- and middle-income countries., Type of Study: Retrospective observational study., Level of Evidence: Level III evidence., (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Published
- 2024
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49. Facilitating Culturally Competent Breast Imaging Care in South Asian Patients.
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Sharma N, Mehta TS, Wahab RA, and Patel MM
- Subjects
- Female, Humans, Asian, Cultural Competency, Culturally Competent Care, Mammography, United States, Breast Neoplasms diagnostic imaging, Breast Neoplasms ethnology, Breast Neoplasms diagnosis
- Abstract
South Asians are a rapidly growing subset of the Asian population in the United States. They comprise people from multiple countries with diverse beliefs, languages, and cultural identities and values. The incidence of breast cancer is rising in South Asian women in the United States, with earlier onset and predilection for HER2-enriched tumors. Despite the rising incidence of breast cancer, participation in screening remains lower than other populations. Health care inequities in South Asian women are multifactorial and may be due to traditional health beliefs and practices, language barriers, cultural differences, and lack of overall awareness. Developing a culturally sensitive environment in breast imaging clinic practice can lead to improved patient care and adherence. Given the scarcity of data specific to the South Asian population in United States, there is a need for health service researchers and practice leaders to obtain more high-quality data to understand the needs of South Asian patient populations., (© Society of Breast Imaging 2024. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
- Published
- 2024
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50. A groundbreaking electrocardiographic observation: "Isoelectric horizontal ST-segment with sharp ST-T angle" a novel sign for acute coronary syndrome.
- Author
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Patel MM, Patel SG, Patel JK, Patel DM, Prajapati PJ, Patel HD, Prajapati JS, Patel LB, and Patel MV
- Subjects
- Humans, Male, Female, Middle Aged, Incidence, Acute Coronary Syndrome diagnosis, Acute Coronary Syndrome physiopathology, Electrocardiography
- Abstract
Consecutive suspected acute coronary syndrome (ACS) cases were categorized into three groups: Group-1 (ST-depression), Group-2 (T-inversion), and Group-3 (remaining cases). Group-3 was subclassified into isoelectric horizontal ST-segment with sharp ST-T-angle (IHST) positive and IHST negative groups. They underwent serial high-sensitive Troponin-I testing. ACS incidence was 77.96 %, with 33.02 %, 15.96 %, and (15.04 %, 35.96 %) of patients in Groups 1, 2, and 3 (IHST positive, IHST negative), respectively. The presence of IHST exhibited higher sensitivity than T-inversion and greater specificity than ST-depression in detecting ACS. The presence of IHST sign additionally detected 15.04 % of ACS. The presence of IHST was significant among group-3 (p = 0.008) as well as the overall ACS cases (p = 0.048)., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
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