1. Somatostatin receptors in GtoPdb v.2023.1
- Author
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Hans-Jürgen Wester, Annamaria Vezzani, Giovanni Tulipano, John E. Taylor, Stefan Schulz, Agnes Schonbrunn, Herbert Schmid, Marcus Schindler, Jean-Claude Reubi, Terry Reisine, Yogesh C. Patel, Anne-Marie O'Carroll, Wolfgang Meyerhof, Shlomo Melmed, Amelie Lupp, Hans-Jürgen Kreienkamp, Patrick P. A. Humphrey, Daniel Hoyer, Leo Hofland, Rebecca Hills, Anthony Harmar, Wasyl Feniuk, Jacques Epelbaum, Pascal Dournaud, Micheal Culler, Zsolt Csaba, Justo P. Castaño, and Corinne Bosquet
- Subjects
General Medicine ,General Chemistry - Abstract
Somatostatin (somatotropin release inhibiting factor) is an abundant neuropeptide, which acts on five subtypes of somatostatin receptor (SST1-SST5; nomenclature as agreed by the NC-IUPHAR Subcommittee on Somatostatin Receptors [98]). Activation of these receptors produces a wide range of physiological effects throughout the body including the inhibition of secretion of many hormones. Endogenous ligands for these receptors are somatostatin-14 (SRIF-14) and somatostatin-28 (SRIF-28). cortistatin-14 has also been suggested to be an endogenous ligand for somatostatin receptors [61].
- Published
- 2023