1. Gender and ethnicity as moderators: Integrative data analysis of multidimensional family therapy randomized clinical trials
- Author
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Kristin Hall, Howard A. Liddle, Craig E. Henderson, Wei Wang, Gayle A. Dakof, Lisa Kan, and Paul E. Greenbaum
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Male ,Family therapy ,medicine.medical_specialty ,Adolescent ,Substance-Related Disorders ,Alternative medicine ,Ethnic group ,Article ,Developmental psychology ,law.invention ,Odds ,Randomized controlled trial ,law ,Ethnicity ,medicine ,Humans ,Sex Distribution ,Child ,General Psychology ,Moderation ,medicine.disease ,Substance abuse ,Treatment Outcome ,Adolescent Behavior ,Sample size determination ,Family Therapy ,Female ,Psychology ,Clinical psychology - Abstract
The extent that participant characteristics are associated with outcome disparities for behavioral treatments generally, and adolescent drug abuse treatments in particular, is arguably one of the most important, albeit difficult to answer questions in the psychotherapy field (Blake, Amaro, Schwartz, & Flinchbaugh, 2001). Limited knowledge about gender and ethnicity as moderators remains ubiquitous in treatment research. Sparse representation of minority individuals in RCTs and paucity of subgroup analyses based on ethnicity has been well-documented. For example, a recent review of NIMH-funded randomized clinical trials, revealed that only 10% and 5% reported moderation analyses for gender and ethnicity, respectively (Mak, Law, Alvidrez, & Perez-Stable, 2007). A major impediment for conducting these subgroup analyses has been small to moderate sample sizes (80% had less than 200 participants). Ethnic and gender subgroup sizes have been seldom more than 40 with consequently little power to test moderation (Mak et al., 2007). From this perspective, the state of the literature stands at odds with a growing emphasis on disseminating evidence-based treatments (EBT) on a wide-scale, and researchers have argued that results from existing RCTs cannot be generalized to individuals from ethnic minority backgrounds (Hall, 2001; Sue, Zane, Hall, & Berger, 2009). Correspondingly, there has been recognition that treatment needs, processes, and outcomes might differ across gender (American Psychological Association, 2007; Blake et al., 2001). Although girls and women generally have been adequately represented in RCTs, few researchers have investigated potential gender differences in treatment effects (Mak et al., 2007).
- Published
- 2015
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