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Nonlinear molecular excitations in DNA have traditionally been modelled using the nonlinear Schr\"odinger equation (NLSE). An alternative approach is based on the plane-base rotator model and the SU(2)/U(1) generalized spin coherent states, which leads to a cubic quintic NLSE. Higher-order nonlinearities are particularly useful for modelling complex interactions, such as those in DNA-protein systems, where multiple competing forces play a significant role. Additionally, the surrounding viscous medium introduces dissipative forces that affect the propagation of molecular excitations, leading to energy dissipation and damping effects. These damping effects are modelled using the quasi-stationary method, which describes the system's near-equilibrium behaviour. In this work, we explore the evolution of nonlinear molecular excitations in DNA-protein systems, accounting for damping effects, and discuss potential applications to the transcription process.

The Heimburg-Jackson model, or thermodynamic soliton theory of nervous impulses, has a well-established record as an alternative model for studying the dynamics of nerve impulses and lipid bilayers. Within this framework, nerve impulses can be represented as nonlinear excitations of low amplitude depicted by the damped nonlinear Schr\"odinger equation and their adiabatic evolution can be analyzed using direct perturbative methods. Based on the foregoing, we carry out the current study using the quasi-stationary approach to obtain the adiabatic evolution of solitons embedded in lipid bilayers under the influence of a viscous elastic fluid. This analysis encompasses liquid-to-gel transition of the lipid bilayers, for whose dark and bright solitons arise, respectively.

Unlike expected from the Hodgkin-Huxley model predictions, in which there is annihilation once orthodromic and antidromic impulses collide, the Heimburg-Jackson model demonstrates that both impulses penetrate each other as it has been shown experimentally. These impulses can be depicted as low amplitude nonlinear excitations in a weakly dissipative soliton model described by the damped NLSE. In view of the above, the Karpman-Solov'ev-Maslov perturbation theory turns out to be ideal to study the interaction and adiabatic evolution of orthodromic and antidromic impulses once axoplasmic fluid is present.

Starting from the effective Hamiltonian arising from the tight binding model, we study the behaviour of low-lying excitations for bilayer graphene placed in periodic external magnetic fields by using irreducible second order supersymmetry transformations. The coupled system of equations describing these excitations is reduced to a pair of periodic Schr\"odinger Hamiltonians intertwined by a second order differential operator. The direct implementation of more general second-order supersymmetry transformations allows to create nonsingular Schr\"odinger potentials with periodicity defects and bound states embedded in the forbidden bands, which turn out to be associated to quasiperiodic magnetic superlattices. Applications in quantum metamaterials stem from the ability to engineer and control such bound states which could lead to a fast development of the subject in the near future.