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Your search keyword '"Pavics, Laszlo"' showing total 22 results
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22 results on '"Pavics, Laszlo"'

7. An isotope-diagnostic approach to Erdheim-Chester's disease of the heart

Author

Palotas, Andras, Bogats, Gabor, Lazar, Mata, Papos, Miklos, Matin, Keyvan, and Pavics, Laszlo

Subjects
Histiocytosis -- Case studies, Histiocytosis -- Diagnosis, Heart diseases -- Case studies, Heart diseases -- Diagnosis, Radioisotopes -- Usage, Radioisotopes -- Health aspects, Musculoskeletal system -- Evaluation, Health
Published
2006

17. FDG PET and acetazolamide-enhancedTc-HMPAO SPET in systemic lupus erythematosus.

Author

Grünwald, Frank, Schomburg, Axel, Badali, Achim, Ruhlmann, Jürgen, Pavics, Laszlo, and Biersack, Hans-J.

Abstract

In systemic lupus erythematosus (SLE), brain and kidney are the most frequently affected organs. Measurements of cerebral blood flow and metabolism by means of positron emission tomography (PET) and single-photon emission tomography (SPET) can contribute to the diagnostic assessment of the involvement of the central nervous system (CNS) in SLE. Functional imaging has been proven to be more sensitive than morphological imaging (magnetic resonance imaging and computed tomography). In this report, we present the case of a 70-year-old female patient, suffering from SLE without symptoms of CNS involvement. In addition to a SPET study using technetium-99m hexamethylpropylene amine oxime (Tc-HMPAO) and a PET scan with fluorine-18 deoxyglucose (FDG), a SPET study after acetazolamide injection was performed in order to assess the cerebral perfusion reserve. While the PET scan showed no major abnormalities, and the baseline SPET study revealed only minor changes, the acetazolamide-enhanced SPET study revealed a marked reduction of the cortical perfusion reserve, particularly in both frontal lobes. It is concluded that 'preclinical' CNS involvement, mainly caused by pathological mechanisms involving the cerebral blood vessels, can be considered to exist in this patient with SLE. [ABSTRACT FROM AUTHOR]

Published
1995
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21. 18FDG PET and acetazolamide-enhanced99mTc-HMPAO SPET in systemic lupus erythematosus

Author

Grünwald, Frank, Schomburg, Axel, Badali, Achim, Ruhlmann, Jürgen, Pavics, Laszlo, and Biersack, Hans-J.

Abstract

In systemic lupus erythematosus (SLE), brain and kidney are the most frequently affected organs. Measurements of cerebral blood flow and metabolism by means of positron emission tomography (PET) and single-photon emission tomography (SPET) can contribute to the diagnostic assessment of the involvement of the central nervous system (CNS) in SLE. Functional imaging has been proven to be more sensitive than morphological imaging (magnetic resonance imaging and computed tomography). In this report, we present the case of a 70-year-old female patient, suffering from SLE without symptoms of CNS involvement. In addition to a SPET study using technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) and a PET scan with fluorine-18 deoxyglucose (18FDG), a SPET study after acetazolamide injection was performed in order to assess the cerebral perfusion reserve. While the PET scan showed no major abnormalities, and the baseline SPET study revealed only minor changes, the acetazolamide-enhanced SPET study revealed a marked reduction of the cortical perfusion reserve, particularly in both frontal lobes. It is concluded that “preclinical” CNS involvement, mainly caused by pathological mechanisms involving the cerebral blood vessels, can be considered to exist in this patient with SLE.

Published
1995
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