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1. [Atropine effect on activity of angiotensin-converting enzyme and carboxypeptidase n in the serum of rats].

Author

Gengin MT, Solov'ev VB, Smetanin VA, Pazialova AA, Simkina OV, Konovalov AN, Kuzichkin DS, Shashkina NK, Gengina NM, and Subbotina KB

Subjects
Animals, Injections, Intraperitoneal, Male, Rats, Time Factors, Atropine pharmacology, Lysine Carboxypeptidase blood, Muscarinic Antagonists pharmacology, Peptidyl-Dipeptidase A blood
Abstract

The effect of a single atropine administration on the activities of angiotensin-converting enzyme and carboxypeptidase N taking part in peptides metabolism was studied. Changes in the enzymes activities after administration were evident during at least 72 h. The role of these enzymes in the metabolism of neuropeptides under the effect of atropine was discussed.

Published
2005

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