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3. Coronary Artery Fistula: A Diagnostic Dilemma

Author

Kumar, Rajesh, primary, Kumar, Jathinder, additional, O’Connor, Cormac, additional, Ullah, Ihsan, additional, Tyrell, Benjamin, additional, Pearson, Ian, additional, Matiullah, Sajjad, additional, and Bainey, Kevin, additional

Published
2023
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4. Markers of risk in patients with acute coronary syndrome treated by percutaneous coronary intervention

Author

Pearson, Ian Russell, Hall, Alistair S., Sivananthan, Mohan, Balmforth, Anthony, and Gale, Christopher

Subjects
616.1
Abstract

Background - The clinical diagnosis and categorisation of Acute Coronary Syndrome (ACS) has changed repeatedly over the last decade as have routine treatment strategies. Hypothesis - that adverse clinical events following PCI, may be predicted from the identification of markers of risk at the time of PCI. Methods - Informed consent was obtained from 968 patients fulfilling detailed inclusion and exclusion criteria surrounding a diagnosis of ACS requiring PCI. Standard medical ACS care was provided. PCI operators, techniques, methods and any decision to treat followed usual practice. Data collection took place at the time of intervention and during active follow-up. Blood sample were collected at baseline and 4 and 12 hours after PCI, being processed and refrigerated. Platelet function was assessed at baseline using the VerifyNow test method. Results – Data collection was over a median follow-up time of 3.56 years. Patients were aged 27 to 90 years and a majority were male (75%). Angiographic complications occurred in 13.2% and total complications in 17.1%. A majority (844; 86%) had neither restenosis nor subsequent unplanned revascularization. Recurrent ACS was 6.7% for year 1 and 1.8% additionally for each year thereafter. Stent thrombosis was observed in 18 (1.8%) cases. Bleeding occurred in 9% across the entire follow-up period, being greatest in the first 12 months. Platelet reactivity was highly variable and optimal with regard to outcome in the range of 179 to 243 (Platelet Reactivity Units PRU). Cardiac biomarkers were commonly elevated after PCI but procedural MI was very rare. H-FABP at baseline was strongly predictive of outcome. Conclusion – Adverse clinical events following PCI, such as stent thrombosis, bleeding and in-stent restenosis, may be predicted from the identification of markers of risk at the time of PCI, particularly by the use of risk scores, platelet function testing and measuring biomarker levels.

Published
2015

5. Fincastle 86

Author

Pearson, Ian, F1tLt

Subjects
ANTISUBMARINE WARFARE - Study and Teaching, BOMBING, NAVIGATION, ETC - Competitions, COMPETITIONS AND MEETS
Abstract

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Published
1987

9. Remote wide angle view broad wavelength viewing system compatible with D-T operations in JET

Author

Balboa, itziar, primary, Rose, Effy, additional, Matthews, Guy, additional, Croft, David, additional, Stamp, Mike F, additional, Silburn, Scott Alan, additional, Williams, John C, additional, Hepple, David, additional, Huber, Alexander, additional, Whetham, Steven, additional, Iglesias, Daniel, additional, Kinna, David, additional, Beldishevski, Misha, additional, Figueiredo, Joao, additional, Perez von Thun, Christian, additional, Jones, Graham, additional, Balshaw, Nick, additional, Horton, Lorne D, additional, Lobel, Robert, additional, Pearson, Ian, additional, Pepperell, Keith, additional, Fishpool, Geoff, additional, Lane, Ben, additional, Zastrow, Klaus-Dieter, additional, Arnoux, Gilles, additional, Bodnar, Gabor, additional, Carman, Paul, additional, Carvalho, Pedro, additional, Conway, Neil, additional, Gupta, Neelam, additional, Huber, Valentina, additional, Kocsis, Gabor, additional, Manzanares, Ana, additional, Puglia, Paulo, additional, Ruiz de Galarreta, Carlota, additional, Marren, Clifford, additional, Otin, Ruben, additional, Naish, Jonathan, additional, and Thompson, Vaughan K, additional

Published
2023
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12. Intravascular lithotripsy-assisted PCI for severely calcified coronary lesions: evaluating the impact on quality of life and outcomes.

Author

Buckley, Anthony J., McCormick, John P., Carey, James, Armstrong, Richard, Maree, Andrew, Hensey, Mark, O'Connor, Stephen, Murphy, Ross, Daly, Caroline, Cosgrave, John, and Pearson, Ian

Abstract

Background: Despite the increased uptake of intravascular lithotripsy (IVL) for treating severely calcified coronary lesions, there is limited patient-level data examining the effect of IVL on quality of life, symptomatology, and outcomes beyond 30 days. We sought to assess demographics, procedural characteristics, outcomes, and impact of IVL on patient-reported angina after a minimum of 6 months follow-up. Methods: A retrospective single-center study was conducted of patients treated with coronary IVL between January and October 2020. Baseline demographics were obtained from electronic patient records and SYNTAX scores were calculated from index coronary angiograms. Technical success and complications were assessed along with clinical outcomes, which included all-cause mortality, myocardial infarction (MI), target lesion revascularization (TLR), and MACE (composite of death, stroke, MI, and TLR). Canadian Cardiovascular Society (CCS) angina classification was assessed at virtual clinical follow-up. Results: Forty-seven consecutive patients were included. At a mean follow-up of 306 ± 74 days, the mean CCS angina score was reduced by 53% post-IVL-assisted PCI (2.9 vs 1.4, p < 0.001). Technical and procedural success were high (94% and 92%, respectively). One patient (2%) met the pre-specified criteria for in-hospital MACE and 4 (9%) met pre-specified MACE at follow-up, including 2 deaths and 2 TLR. Procedural complications included coronary dissection (11%) and coronary perforation (6%) and were managed either conservatively or with PCI. Conclusions: Coronary IVL is a safe and effective adjunctive therapy for treating heavily calcified coronary lesions. This cohort shows high procedural success and a significant reduction in CCS angina at follow-up. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Factors associated with adverse COVID-19 outcomes in patients with psoriasis—insights from a global registry–based study

Author

Mahil, Satveer K., primary, Dand, Nick, additional, Mason, Kayleigh J., additional, Yiu, Zenas Z.N., additional, Tsakok, Teresa, additional, Meynell, Freya, additional, Coker, Bola, additional, McAteer, Helen, additional, Moorhead, Lucy, additional, Mackenzie, Teena, additional, Rossi, Maria Teresa, additional, Rivera, Raquel, additional, Mahe, Emmanuel, additional, Carugno, Andrea, additional, Magnano, Michela, additional, Rech, Giulia, additional, Balogh, Esther A., additional, Feldman, Steven R., additional, De La Cruz, Claudia, additional, Choon, Siew Eng, additional, Naldi, Luigi, additional, Lambert, Jo, additional, Spuls, Phyllis, additional, Jullien, Denis, additional, Bachelez, Hervé, additional, McMahon, Devon E., additional, Freeman, Esther E., additional, Gisondi, Paolo, additional, Puig, Luis, additional, Warren, Richard B., additional, Di Meglio, Paola, additional, Langan, Sinéad M., additional, Capon, Francesca, additional, Griffiths, Christopher E.M., additional, Barker, Jonathan N., additional, Smith, Catherine H., additional, Shah, Aadarsh, additional, Barea, Alberto, additional, Romero-Maté, Alberto, additional, Singapore, Alekya, additional, Paolino, Alexandra, additional, Mwale, Alice, additional, Morales Callaghan, Ana Maria, additional, Martinez, Ana, additional, DeCrescenzo, Andrew, additional, Pink, Andrew E., additional, Jones, Ann, additional, Sergeant, Ann, additional, Essex, Annette, additional, Bewley, Anthony, additional, Makrygeorgou, Areti, additional, van Huizen, Astrid, additional, Pérez-Suárez, Beatriz, additional, Farida, Benhadou, additional, Claréus, Birgitta Wilson, additional, Prims, Carla Tubau, additional, Davis, Carrie, additional, Quinlan, Catherine, additional, Maybury, Catriona, additional, Cesar, Gonzalez A., additional, Barclay, Charlotte, additional, Greco, Claudio, additional, Brassard, Danielle, additional, Cummings, Deanna, additional, Kolli, Deepti, additional, Descamps, Vincent, additional, Genao, Diana Ruiz, additional, Carras, Efrossini, additional, Hawryluk, Elena, additional, Martínez-García, Eliseo, additional, Klujszo, Elzbieta, additional, Dwyer, Emily, additional, Toni, Emmanuel, additional, Sonkoly, Enikö, additional, Loayza, Enrique, additional, Daudén, Esteban, additional, Valenzuela, Fernando, additional, Popov, Georgi, additional, King, Georgie, additional, Celine, Girard, additional, Aparicio, Gloria, additional, Johnston, Graham A., additional, Cardozo, Gustavo Anibal, additional, Pearson, Ian, additional, Yanguas, Ignacio, additional, Weisman, Jamie, additional, Carolan, Jennifer E., additional, Hughes, Jenny, additional, Ortiz-Salvador, Jose-Maria, additional, Carrascosa, Jose-Manuel, additional, Schwartz, Joseph J., additional, Jackson, Karina, additional, Kerisit, Kathryn G., additional, Wu, Keith, additional, Asfour, Leila, additional, de Graaf, Leontien, additional, Lesort, Cécile, additional, Meuleman, Lieve, additional, Eidsmo, Liv, additional, Skov, Lone, additional, Gribben, Lorraine, additional, Rustin, Malcolm, additional, Velasco, Manel, additional, Panchal, Manisha, additional, Lakhan, Manpreet, additional, Franco, Manuel D., additional, Svensson, Marie-Louise, additional, Vandaele, Mark, additional, Marovt, Maruska, additional, Zargari, Omid, additional, De Caso, Pablo, additional, Varela, Paulo, additional, Jenkin, Peter, additional, Phan, Céline, additional, Hampton, Philip, additional, Goldsmith, Portia, additional, Bak, Rachel, additional, Speeckaert, Reinhart, additional, Romiti, Ricardo, additional, Woolf, Richard, additional, Mercado-Seda, Rogelio, additional, Khatun, Rohima, additional, Ceovic, Romana, additional, Taberner, Rosa, additional, Cohen, Russell W., additional, Stefanescu, Simina, additional, Kirk, Sarah, additional, Reeken, Saskia, additional, Ayob, Shanti, additional, Pérez-Barrio, Silvia, additional, Piaserico, Stefano, additional, Hoey, Susannah, additional, Torres, Tiago, additional, Talme, Toomas, additional, Desai, Trupti V., additional, van Geest, Adrienne J., additional, King, Victoria, additional, Di Lernia, Vito, additional, Koreja, Zahira, additional, and Hasab, Vito Zeeshaan, additional

Published
2021
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28. Power and participation in a general union : patterns of organisation and democracy in three GMB regions

Author

Pearson, Ian

Subjects
331, HD Industries. Land use. Labor
Abstract

This study is about the organisation and government of the General Municipal and Boilermakers' from 1970 to 1985. Its focus is, as far as is known, unique in that it concentrates primarily on government at the regional level, examining the GMB's Birmingham, Liverpool and Northern regions. Rather than focusing explicitly on the policy issues related to recent legislation, it analyses the wider issues of power and participation relevant to the debate on union democracy. The thesis adopts an eclectic approach to union democracy, synthesising previous approaches within the framework of the vertical and horizontal dispersion of decision making developed by Undy et al, which is given a prescriptive dimension. The regional focus, and secondary focuses on intervening variables within the framework, are principally examined through conducting structured interviews with members and officers at all levels of the union. The research work is divided into four chapters, which follow chapters reviewing the literature and presenting the research focus, and giving an historical overview of the union up until the research period commences. The first examines the national level changes since 1970 and membership participation in the national political system. The other three chapters have a specific regional focus analysing regional variations in membership growth and participation at the local level; the locus of regional power and variations in participation in regional government; and membership participation in collective bargaining. The research contributes to knowledge of trade union government at the regional level; an almost completely explored and, it is argued, an important area which requires further research. It demonstrates the significant extent of regional variations within a single union and shows how these have led to markedly different levels of membership participation in decision making structures in the three regions. It shows that the commonly held view that GMB regional secretaries are barons of their own area is misplaced, noting constraints which prevent oligarchic domination of regions. It also highlights the pervasive, but long since neglected, influence of union constitutional provisions as a factor affecting union democracy. Finally, it suggests that the eclectic framework could be usefully adopted by future contributions to union democracy research.

Published
1987

29. The next Google

Author

Buxton, Bill, Hayward, Vincent, Pearson, Ian, Kärkkäinen, Leo, Greiner, Helen, Dyson, Esther, Ito, Joi, Chung, Anshe, Kelly, Kevin, and Schillace, Sam

Published
2008
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30. A timeline for technology: to the year 2030 and beyond; What's ahead in technology, and what will it mean? This new timeline offers a glimpse of likely developments--and of how they may change our lives

Author

Pearson, Ian and Neild, Ian

Subjects
Artificial intelligence -- Forecasts and trends -- Usage, Technology and civilization -- Forecasts and trends -- Usage, Biotechnology -- Forecasts and trends -- Usage, Robots -- Usage -- Forecasts and trends, Robotics -- Forecasts and trends -- Usage, Business, general, Sociology and social work, Market trend/market analysis, Artificial intelligence, Robot, Usage, Forecasts and trends
Abstract

Editor's Note The Technology Timeline by BT futurologists Ian Neild and Ian Pearson is an ongoing project to keep decision makers and organizations informed about probable developments and their potential [...]

Published
2006

31. Designing and implementing pharmaceutical clean rooms: overview of the key issues and choices to consider when designing and implementing a clean room for a new pharmaceutical product or process

Author

Pearson, Ian M.

Subjects
Clean rooms -- Analysis -- Usage -- Standards, Pharmaceutical industry -- Management -- Standards, Business, Pharmaceuticals and cosmetics industries, Company business management, Management, Standards, Analysis, Usage
Abstract

Clean rooms are now used in a variety of industries, including microelectronics, nanotechnology, defence, pharmaceuticals and biotechnology. They range from small rooms and large suites to modular purpose-built structures feeding [...]

Published
2005

32. Case 6

Author

Pearson, Ian C. and Cliff, S.

Published
2003

33. Containment levels and facility design

Author

Pearson, Ian

Subjects
Hazardous substances, Business, Pharmaceuticals and cosmetics industries, Design and construction
Abstract

The influence of containment classification in facility design cannot be underestimated. It can, for example, determine the extent of the design process and the level of equipment needed to safeguard [...]

Published
2003

34. Cult of the guitar god

Author

Pearson, Ian

Subjects
Musicians -- Appreciation, Music fans -- Behavior
Abstract

It's not easy being obsessive. Just ask any Richard Thompson fan In the womb, a child begins to hear about four months into term. Diligent parents will expose the fetus […]

Published
1998

36. Potential for cadaveric organ retrieval in New South Wales

Author

Hibberd, Adrian D., Pearson, Ian Y., McCosker, Cate J., Chapman, Jeremy R., Macdonald, Graham J., Thompson, John F., O'Connell, Dianne L., Mohacsi, Paula J., McLoughlin, Moira P., Spratt, Phillip M., Compton, Jeffrey S., and Brown, Mark A.

Subjects
Organ donors -- Statistics, Donation of organs, tissues, etc. -- Statistics, Health, Statistics
Abstract

the study hospitals was the same as in the other New South Wales hospitals, the projected donor rate for New South Wales was 18/million population/year (10 to 26); the projected [...]

Published
1992

37. Terminal sex

Author

Pearson, Ian

Subjects
ALEX (Program development software) -- Usage, Computer networks -- Services, Telecommunications services industry -- Services, Bell Canada -- Services
Published
1991

38. Thou shalt not ignore the West

Author

Pearson, Ian

Subjects
Conservative Party of Canada -- Political activity, Prairie Provinces -- Political aspects, Western Canada -- Political aspects
Published
1990

39. Lockerbie

Author

Pearson, Ian B.

Published
1989

44. THE UK AND GLOBAL CLIMATE CHANGE.

Author

Pearson, Ian

Subjects
*GLOBAL warming, *CLIMATE change
Abstract

The article presents the speech "The Uk and Global Climate Change," by Ian Pearson, Minister of State for Climate Change and Environment for the United Kingdom, delivered at the United Kingdom Climate Impacts Programme User Forum, March 15, 2007. Pearson discusses the issue of global warming and the role of the United Kingdom in understanding and adapting to climatic changes.

Published
2007

45. The polka king

Author

Pearson, Ian

Subjects
Musicians, Canadian -- Criticism and interpretation, Polkas -- Criticism and interpretation
Published
1990

47. Beyond digital

Author

Pearson, Ian

Subjects
Technology and civilization -- Forecasts and trends -- Social aspects, Computers and civilization -- Forecasts and trends -- Social aspects, Internet -- Social aspects -- Forecasts and trends, Literature/writing, Political science, Market trend/market analysis, Internet, Social aspects, Forecasts and trends
Abstract

BT's futurologist Ian Pearson reckons that, instead of making our lives simpler, technology will actually make them more complex The huge technological changes we're going to see over the next [...]

Published
2000

48. A thriving cyberfuture

Author

PEARSON, IAN

Subjects
Architectural firms -- Information management, Architecture and design industries, Construction and materials industries
Abstract

Information technology will soon change all professions. Some will be almost wiped out by smart machines and e-commerce, others will change dramatically. For architects, work will also shift considerably but [...]

Published
2000

49. The Next 20 Years in Technology: Timeline and Commentary

Author

Pearson, Ian D.

Subjects
Technology -- Forecasts and trends, Future life -- Forecasts and trends, Business, general, Sociology and social work, Market trend/market analysis, Forecasts and trends
Abstract

What new technological developments can we reasonably expect over the next two decades? A British telecommunications analyst provides some surprising answers. No one knows precisely what life will be like [...]

Published
2000

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