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23 results on '"Peckner, Ryan"'

1. Preclinical Pharmacology of S-1117, a Novel Engineered Fc-fused IgG Cleaving Enzyme, for Chronic Treatment of Autoantibody-mediated Diseases (P4-14.018)

Author

Mascanfroni, Ivan, primary, Manasson, Julia, additional, Pellerin, Alex, additional, Sanmarco, Liliana, additional, Anderson, Jordan, additional, Rollins, Nathan, additional, Newton, Andita, additional, Peckner, Ryan, additional, Xing, Yi, additional, Higginson-Scott, Nathan, additional, Sundy, John, additional, and Otipoby, Kevin, additional

Published
2024
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3. M\'obius disjointness for homogeneous dynamics

Author

Peckner, Ryan

Subjects
Mathematics - Number Theory, Mathematics - Dynamical Systems, 11N37, 22D40, 37C40, 22F30, 22E40, 22E46
Abstract

We prove Sarnak's M\"obius disjointness conjecture for all unipotent translations on homogeneous spaces of real connected Lie groups. Namely, we show that if $G$ is any such group, $\Gamma\subset G$ a lattice, and $u\in G$ an Ad-unipotent element, then for every $x\in\Gamma\backslash G$ and every continuous, bounded function $f$ on $\Gamma\backslash G$, the sequence $f(xu^{n})$ cannot correlate with the M\"obius function on average., Comment: 35 pages, proof of proposition 3.10 contained an error that has been corrected

Published
2015
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5. Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds

Author

Dele-Oni, Deborah O., Christianson, Karen E., Egri, Shawn B., Vaca Jacome, Alvaro Sebastian, DeRuff, Katherine C., Mullahoo, James, Sharma, Vagisha, Davison, Desiree, Ko, Tak, Bula, Michael, Blanchard, Joel, Young, Jennie Z., Litichevskiy, Lev, Lu, Xiaodong, Lam, Daniel, Asiedu, Jacob K., Toder, Caidin, Officer, Adam, Peckner, Ryan, MacCoss, Michael J., Tsai, Li-Huei, Carr, Steven A., Papanastasiou, Malvina, and Jaffe, Jacob D.

Published
2021
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6. Uniqueness of the measure of maximal entropy for the squarefree flow

Author

Peckner, Ryan

Subjects
Mathematics - Dynamical Systems, Mathematics - Number Theory, 37B10, 28D20, 11N64, 11N69
Abstract

The squarefree flow is a natural dynamical system whose topological and ergodic properties are closely linked to the behavior of squarefree numbers. We prove that the squarefree flow carries a unique measure of maximal entropy and express this measure explicitly in terms of a skew-product of a Kronecker and a Bernoulli system. Using this characterization and a number-theoretic argument, we then show that the unique maximum entropy measure fails to possess the Gibbs property., Comment: 18 pages. Minor changes from previous version; to appear in Israel J. Math

Published
2012

7. Low-lying Zeros of Number Field $L$-functions

Author

Miller, Steven J. and Peckner, Ryan

Subjects
Mathematics - Number Theory, 11M26 (primary), 11M41, 15A52 (secondary)
Abstract

One of the most important statistics in studying the zeros of L-functions is the 1-level density, which measures the concentration of zeros near the central point. Fouvry and Iwaniec [FI] proved that the 1-level density for L-functions attached to imaginary quadratic fields agrees with results predicted by random matrix theory. In this paper, we show a similar agreement with random matrix theory occurring in more general sequences of number fields. We first show that the main term agrees with random matrix theory, and similar to all other families studied to date, is independent of the arithmetic of the fields. We then derive the first lower order term of the 1-level density, and see the arithmetic enter., Comment: Version 1.1, 27 pages

Published
2010

8. A unitary test of the Ratios Conjecture

Author

Goes, John, Jackson, Steven, Miller, Steven J., Montague, David, Ninsuwan, Kesinee, Peckner, Ryan, and Pham, Thuy

Subjects
Mathematics - Number Theory, 11M26 (primary), 11M41, 15B52 (secondary)
Abstract

The Ratios Conjecture of Conrey, Farmer and Zirnbauer predicts the answers to numerous questions in number theory, ranging from n-level densities and correlations to mollifiers to moments and vanishing at the central point. The conjecture gives a recipe to generate these answers, which are believed to be correct up to square-root cancelation. These predictions have been verified, for suitably restricted test functions, for the 1-level density of orthogonal and symplectic families of L-functions. In this paper we verify the conjecture's predictions for the unitary family of all Dirichlet $L$-functions with prime conductor; we show square-root agreement between prediction and number theory if the support of the Fourier transform of the test function is in (-1,1), and for support up to (-2,2) we show agreement up to a power savings in the family's cardinality., Comment: Version 2: 24 pages, provided additional details, fixed some small mistakes and expanded the exposition in places

Published
2009
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9. The promise of machine learning: using Seismic’s IMPACT platform to design IgG cleaving enzymes for chronic treatment of autoimmune diseases

Author

Pellerin, Alex, primary, Anderson, Jordan, additional, Rollins, Nathan, additional, Sanmarco, Liliana, additional, Newton, Andita, additional, Le, Nam, additional, Shin, June, additional, Hoel, Chris, additional, Cianci, Michael, additional, Hoyt, Emily, additional, Mojta, Shanell, additional, Hollfelder, Melissa, additional, Cipoletta, Daniela, additional, Peckner, Ryan, additional, Higginson-Scott, Nathan, additional, Otipoby, Kevin, additional, and Mascanfroni, Ivan, additional

Published
2023
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14. Causal Interactions from Proteomic Profiles: Molecular Data Meets Pathway Knowledge

Author

Babur, Ozgun, primary, Luna, Augustin, additional, Korkut, Anil, additional, Durupinar, Funda, additional, Siper, Metin Can, additional, Dogrusoz, Ugur, additional, Jacome, Alvaro S.V., additional, Peckner, Ryan, additional, Christianson, Karen E., additional, Jaffe, Jacob, additional, Spellman, Paul, additional, Aslan, Joseph, additional, Sander, Chris, additional, and Demir, Emek, additional

Published
2020
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16. Avant-garde: An automated data-driven DIA data curation tool

Author

Jacome, Alvaro Sebastian Vaca, primary, Peckner, Ryan, additional, Shulman, Nicholas, additional, Krug, Karsten, additional, DeRuff, Katherine C., additional, Officer, Adam, additional, MacLean, Brendan, additional, MacCoss, Michael J., additional, Carr, Steven A., additional, and Jaffe, Jacob D., additional

Published
2019
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19. A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

Author

Litichevskiy, Lev, primary, Peckner, Ryan, additional, Abelin, Jennifer G., additional, Asiedu, Jacob K., additional, Creech, Amanda L., additional, Davis, John F., additional, Davison, Desiree, additional, Dunning, Caitlin M., additional, Egertson, Jarrett D., additional, Egri, Shawn, additional, Gould, Joshua, additional, Ko, Tak, additional, Johnson, Sarah A., additional, Lahr, David L., additional, Lam, Daniel, additional, Liu, Zihan, additional, Lyons, Nicholas J., additional, Lu, Xiaodong, additional, MacLean, Brendan X., additional, Mungenast, Alison E., additional, Officer, Adam, additional, Natoli, Ted E., additional, Papanastasiou, Malvina, additional, Patel, Jinal, additional, Sharma, Vagisha, additional, Toder, Courtney, additional, Tubelli, Andrew A., additional, Young, Jennie Z., additional, Carr, Steven A., additional, Golub, Todd R., additional, Subramanian, Aravind, additional, MacCoss, Michael J., additional, Tsai, Li-Huei, additional, and Jaffe, Jacob D., additional

Published
2018
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20. A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

Author

Litichevskiy, Lev, primary, Peckner, Ryan, additional, Abelin, Jennifer G., additional, Asiedu, Jacob K., additional, Creech, Amanda L., additional, Davis, John F., additional, Davison, Desiree, additional, Dunning, Caitlin M., additional, Egertson, Jarrett D., additional, Egri, Shawn, additional, Gould, Joshua, additional, Ko, Tak, additional, Johnson, Sarah A., additional, Lahr, David L., additional, Lam, Daniel, additional, Liu, Zihan, additional, Lyons, Nicholas J., additional, Lu, Xiaodong, additional, MacLean, Brendan X., additional, Mungenast, Alison E., additional, Officer, Adam, additional, Natoli, Ted E., additional, Papanastasiou, Malvina, additional, Patel, Jinal, additional, Sharma, Vagisha, additional, Toder, Courtney, additional, Tubelli, Andrew A., additional, Young, Jennie Z., additional, Carr, Steven A., additional, Golub, Todd R., additional, Subramanian, Aravind, additional, MacCoss, Michael J., additional, Tsai, Li-Huei, additional, and Jaffe, Jacob D., additional

Published
2017
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23. A unitary test of the Ratios Conjecture

Author

Goes, John, primary, Jackson, Steven, additional, Miller, Steven J., additional, Montague, David, additional, Ninsuwan, Kesinee, additional, Peckner, Ryan, additional, and Pham, Thuy, additional

Published
2010
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