3,703 results on '"Pedersen, O."'
Search Results
2. Human leukocyte antigen system associations in Malassezia-related skin diseases
- Author
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Lindsø Andersen, P., Jemec, G. B., Erikstrup, C., Didriksen, M., Dinh, K. M., Mikkelsen, S., Sørensen, E., Nielsen, K. R., Bruun, M. T., Hjalgrim, H., Hansen, T. F., Sækmose, S. G., Ostrowski, S. R., Saunte, D. M. L., and Pedersen, O. B.
- Published
- 2023
- Full Text
- View/download PDF
3. TRC Combi Box: A Compact Inline Melt Treatment Unit for Continuous Casting
- Author
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Gorsunova-Balkenhol, M., Badowski, M., Betzing, M., Stotz, J., Pedersen, Ø., and Broek, Stephan, editor
- Published
- 2023
- Full Text
- View/download PDF
4. Irradiance, Water Column O2, and Tide Drive Internal O2 Dynamics and Meristem H2S Detection in the Dominant Caribbean-Tropical Atlantic Seagrass, Thalassia testudinum
- Author
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Koch, M. S., Johnson, C. R., Madden, C. J., and Pedersen, O.
- Published
- 2022
- Full Text
- View/download PDF
5. Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials
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't Hart, L.M., Abdalla, M., Adam, J., Adamski, J., Adragni, K., Allin, K.H., Arumugam, M., Atabaki Pasdar, N., Baltauss, T., Banasik, K.B., Baum, P., Bell, J.D., Bergstrom, M., Beulens, J.W., Bianzano, S., Bizzotto, R., Bonneford, A., Brorsson, C.A.B., Brown, A.A., Brunak, S.B., Cabrelli, L., Caiazzo, R., Canouil, M., Dale, M., Davtian, D., Dawed, A.Y., De Masi, F.M., de Preville, N., Dekkers, K.F., Dermitzakis, E.T., Deshmukh, H.A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., Elders, P.J.M., Engel Thomas, C.E.T., Engelbrechtsen, L., Eriksen, R.G., Eriksen, R.E., Fan, Y., Fernandez, J., Ferrer, J., Fitipaldi, H., Forgie, I.M., Forman, A., Franks, P.W., Frau, F., Fritsche, A., Froguel, P., Frost, G., Gassenhuber, J., Giordano, G.N., Giorgino, T., Gough, S., Graefe-Mody, U., Grallert, H., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V.G., Gupta, R.G., Haid, M., Hansen, T., Hansen, T.H., Hattersley, A.T., Haussler, R.S., Heggie, A.J., Hennige, A.M., Hill, A.V., Holl, R.W., Hong, M.-G., Hudson, M., Jablonka, B., Jennison, C., Jiao, J., Johansen, J.J., Jones, A.G., Jonsson, A., Karaderi, T.K., Kaye, J., Klintenberg, M., Koivula, R.W., Kokkola, T., Koopman, A.D.M., Kurbasic, A, Kuulasmaa, T., Laakso, M., Lehr, T., Loftus, H., Lundbye Allesøe, R.L.A, Mahajan, A., Mari, A., Mazzoni, G.M., McCarthy, M.I., McDonald, T.J., McEvoy, D., McRobert, N., McVittie, I., Mourby, M., Musholt, P., Mutie, P, Nice, R., Nicolay, C., Nielsen, A.M.N., Nilsson, B.N., Palmer, C.N., Pattou, F., Pavo, I., Pearson, E.R., Pedersen, O., Pedersen, H.K.P., Perry, M.H., Pomares-Millan, H., Ramisch, A., Rasmussen, S.R., Raverdi, V., Ridderstrale, M., Robertson, N., Roderick, R.C., Rodriquez, M., Ruetten, H., Rutters, F., Sackett, W., Scherer, N., Schwenk, J.M., Shah, N., Sharma, S., Sihinevich, I., Sondertoft, N.B., Staerfeldt, H., Steckel-Hamann, B., Teare, H., Thomas, M.K., Thomas, E.L., Thomsen, H.S., Thorand, B., Thorne, C.E., Tillner, J., Troen Lundgaard, A.T.L., Troll, M., Tsirigos, K.D.T., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vestergaard, H., Viñuela, A., Vogt, J.K, Wad Sackett, P.W.S, Wake, D., Walker, M., Wesolowska-Andersen, A., Whitcher, B., White, M.W., Wu, H., Dawed, Adem Y, Mari, Andrea, Brown, Andrew, McDonald, Timothy J, Li, Lin, Wang, Shuaicheng, Hong, Mun-Gwan, Sharma, Sapna, Robertson, Neil R, Mahajan, Anubha, Wang, Xuan, Walker, Mark, Gough, Stephen, Hart, Leen M ‘t, Zhou, Kaixin, Forgie, Ian, Ruetten, Hartmut, Pavo, Imre, Bhatnagar, Pallav, Jones, Angus G, and Pearson, Ewan R
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- 2023
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6. Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
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Sterenborg, R.B.T.M., Steinbrenner, I., Li, Yong, Bujnis, M.N., Naito, T., Marouli, E., Galesloot, T.E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B.O., Bandinelli, S., Beekman, M., Beilby, J.P., Bork-Jensen, J., Boutin, T., Brody, J.A., Brown, S.J., Brumpton, B., Campbell, P.J., Cappola, A.R., Ceresini, G., Chaker, L., Chasman, D.I., Concas, M.P., Coutinho de Almeida, Rodrigo, Cross, S.M., Cucca, F., Deary, I.J., Kjaergaard, A.D., Echouffo Tcheugui, J.B., Ellervik, C., Eriksson, J.G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S.E., Grarup, N., Gunjača, I., Hansen, T., Harding, B.N., Harris, S.E., Haunsø, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J.W., Kajantie, E., Kanters, J.K., Kårhus, L.L., Kiemeney, L.A.L.M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, Shuo, Liewald, D.C.M., Linneberg, A., Lominchar, J.V.T., Luan, Jian'an, Martin, N.G., Matana, A., Meima, M.E., Meitinger, T., Meulenbelt, I., Mitchell, B.D., Møllehave, L.T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R.T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C.N.A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polašek, O., Pramstaller, P.P., Psaty, B.M., Punda, A., Ray, D., Redmond, P., Richards, J.B., Ridker, P.M., Russ, T.C., Ryan, K.A., Olesen, M.S., Schultheiss, U.T., Selvin, E., Siddiqui, M.K., Teumer, A., Medici, M., Sterenborg, R.B.T.M., Steinbrenner, I., Li, Yong, Bujnis, M.N., Naito, T., Marouli, E., Galesloot, T.E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B.O., Bandinelli, S., Beekman, M., Beilby, J.P., Bork-Jensen, J., Boutin, T., Brody, J.A., Brown, S.J., Brumpton, B., Campbell, P.J., Cappola, A.R., Ceresini, G., Chaker, L., Chasman, D.I., Concas, M.P., Coutinho de Almeida, Rodrigo, Cross, S.M., Cucca, F., Deary, I.J., Kjaergaard, A.D., Echouffo Tcheugui, J.B., Ellervik, C., Eriksson, J.G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S.E., Grarup, N., Gunjača, I., Hansen, T., Harding, B.N., Harris, S.E., Haunsø, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J.W., Kajantie, E., Kanters, J.K., Kårhus, L.L., Kiemeney, L.A.L.M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, Shuo, Liewald, D.C.M., Linneberg, A., Lominchar, J.V.T., Luan, Jian'an, Martin, N.G., Matana, A., Meima, M.E., Meitinger, T., Meulenbelt, I., Mitchell, B.D., Møllehave, L.T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R.T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C.N.A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polašek, O., Pramstaller, P.P., Psaty, B.M., Punda, A., Ray, D., Redmond, P., Richards, J.B., Ridker, P.M., Russ, T.C., Ryan, K.A., Olesen, M.S., Schultheiss, U.T., Selvin, E., Siddiqui, M.K., Teumer, A., and Medici, M.
- Abstract
Contains fulltext : 304858.pdf (Publisher’s version ) (Open Access), To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals of European ancestry, including reference range thyrotropin (TSH), free thyroxine (FT4), free and total triiodothyronine (T3), proxies for metabolism (T3/FT4 ratio) as well as dichotomized high and low TSH levels. We revealed 259 independent significant associations for TSH (61% novel), 85 for FT4 (67% novel), and 62 novel signals for the T3 related traits. The loci explained 14.1%, 6.0%, 9.5% and 1.1% of the total variation in TSH, FT4, total T3 and free T3 concentrations, respectively. Genetic correlations indicate that TSH associated loci reflect the thyroid function determined by free T3, whereas the FT4 associations represent the thyroid hormone metabolism. Polygenic risk score and Mendelian randomization analyses showed the effects of genetically determined variation in thyroid function on various clinical outcomes, including cardiovascular risk factors and diseases, autoimmune diseases, and cancer. In conclusion, our results improve the understanding of thyroid hormone physiology and highlight the pleiotropic effects of thyroid function on various diseases.
- Published
- 2024
7. Recent progress in understanding the cellular and genetic basis of plant responses to low oxygen hold promise for developing flood-resilient crops
- Author
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Fagerstedt, K V, primary, Pucciariello, C, additional, Pedersen, O, additional, and Perata, P, additional
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- 2023
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8. Genome-wide association study of amidoarone-induced hypothyroidism
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Rand, S, primary, Olesen, M S, additional, Ostrowski, S R, additional, Sorensen, E, additional, Pedersen, O B, additional, Bundgaard, H, additional, and Ghouse, J, additional
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- 2023
- Full Text
- View/download PDF
9. A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
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Grarup, N, Moltke, I, Jorgensen, ME, Bjerregaard, P, Treebak, JT, Korneliussen, TS, Andersen, MA, Nielsen, TS, Krarup, NT, Linneberg, A, Wang, J, Pedersen, O, Nielsen, R, Albrechtsen, A, and Hansen, T
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Clinical Sciences ,Paediatrics and Reproductive Medicine ,Public Health and Health Services ,Endocrinology & Metabolism - Published
- 2014
10. History of cardiovascular disease and cardiovascular biomarkers are associated with 30-day mortality in patients with hip fracture
- Author
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Norring-Agerskov, D., Madsen, C. M., Bathum, L., Pedersen, O. B., Lauritzen, J. B., Jørgensen, N. R., and Jørgensen, H. L.
- Published
- 2019
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11. Human leukocyte antigen system associations in Malassezia-related skin diseases
- Author
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Lindsø Andersen, P., Jemec, G. B., Erikstrup, C., Didriksen, M., Dinh, K. M., Mikkelsen, S., Sørensen, E., Nielsen, K. R., Bruun, M. T., Hjalgrim, H., Hansen, T. F., Sækmose, S. G., Ostrowski, S. R., Saunte, D. M. L., and Pedersen, O. B.
- Subjects
Malassezia folliculitis ,Major histocompatibility complex ,Head and neck dermatitis ,Seborrheic dermatitis ,Dermatology ,General Medicine ,Pityriasis versicolor ,Blood donors - Abstract
Background: The human leukocyte antigen system (HLA) is divided into two classes involved in antigen presentation: class I presenting intracellular antigens and class II presenting extracellular antigens. While susceptibility to infections is correlated with the HLA system, data on associations between HLA genotypes and Malassezia-related skin diseases (MRSD) are lacking. Thus, the objective of this study was to investigate associations between HLA alleles and MRSD.Materials and methods: Participants in The Danish Blood Donor Study (2010-2018) provided questionnaire data on life style, anthropometric measures, and registry data on filled prescriptions. Genotyping was done using Illumina Infinium Global Screening Array, and HLA alleles were imputed using the HIBAG algorithm. Cases and controls were defined using filled prescriptions on topical ketoconazole 2% as a proxy of MRSD. Logistic regressions assessed associations between HLA alleles and MRSD adjusted for confounders and Bonferroni corrected for multiple tests.Results: A total of 9455 participants were considered MRSD cases and 24,144 participants as controls. We identified four risk alleles B*57:01, OR 1.19 (95% CI: 1.09-1.31), C*01:02, OR 1.19 (95% CI: 1.08-1.32), C*06:02, OR 1.14 (95% CI: 1.08-1.22), and DRB1*01:01, OR 1.10 (95% CI: 1.04-1.17), and two protective alleles, DQB1*02:01, OR 0.89 (95% CI: 0.85-0.94), and DRB1*03:01, OR 0.89 (95% CI: 0.85-0.94).Conclusion: Five novel associations between HLA alleles and MRSD were identified in our cohort, and one previous association was confirmed. Future studies should assess the correlation between Malassezia antigens and antigen-binding properties of the associated HLA alleles. Background: The human leukocyte antigen system (HLA) is divided into two classes involved in antigen presentation: class I presenting intracellular antigens and class II presenting extracellular antigens. While susceptibility to infections is correlated with the HLA system, data on associations between HLA genotypes and Malassezia-related skin diseases (MRSD) are lacking. Thus, the objective of this study was to investigate associations between HLA alleles and MRSD.Materials and methods: Participants in The Danish Blood Donor Study (2010-2018) provided questionnaire data on life style, anthropometric measures, and registry data on filled prescriptions. Genotyping was done using Illumina Infinium Global Screening Array, and HLA alleles were imputed using the HIBAG algorithm. Cases and controls were defined using filled prescriptions on topical ketoconazole 2% as a proxy of MRSD. Logistic regressions assessed associations between HLA alleles and MRSD adjusted for confounders and Bonferroni corrected for multiple tests.Results: A total of 9455 participants were considered MRSD cases and 24,144 participants as controls. We identified four risk alleles B*57:01, OR 1.19 (95% CI: 1.09-1.31), C*01:02, OR 1.19 (95% CI: 1.08-1.32), C*06:02, OR 1.14 (95% CI: 1.08-1.22), and DRB1*01:01, OR 1.10 (95% CI: 1.04-1.17), and two protective alleles, DQB1*02:01, OR 0.89 (95% CI: 0.85-0.94), and DRB1*03:01, OR 0.89 (95% CI: 0.85-0.94).Conclusion: Five novel associations between HLA alleles and MRSD were identified in our cohort, and one previous association was confirmed. Future studies should assess the correlation between Malassezia antigens and antigen-binding properties of the associated HLA alleles.
- Published
- 2022
12. The Potential Role of Plant Oxygen and Sulphide Dynamics in Die-off Events of the Tropical Seagrass, Thalassia testudinum
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Borum, J., Pedersen, O., Greve, T. M., Frankovich, T. A., Zieman, J. C., Fourqurean, J. W., and Madden, C. J.
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- 2005
13. Cohort description: The Danish study of Functional Disorders
- Author
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Dantoft TM, Ebstrup JF, Linneberg A, Skovbjerg S, Madsen AL, Mehlsen J, Brinth L, Eplov LF, Carstensen TW, Schroder A, Fink PK, Mortensen EL, Hansen T, Pedersen O, and Jørgensen T
- Subjects
Functional somatic syndromes ,medically unexplained symptoms ,epidemiology ,longitudinal cohort study ,pathophysiology ,risk factors ,Infectious and parasitic diseases ,RC109-216 - Abstract
Thomas Meinertz Dantoft,1 Jeanette Frost Ebstrup,1 Allan Linneberg,1–3 Sine Skovbjerg,1 Anja Lykke Madsen,1 Jesper Mehlsen,4 Louise Brinth,4 Lene Falgaard Eplov,5 Tina Wisbech Carstensen,6,7 Andreas Schroder,6,7 Per Klausen Fink,6,7 Erik Lykke Mortensen,8 Torben Hansen,9 Oluf Pedersen,9 Torben Jørgensen1,10,11 1Research Centre for Prevention and Health, The Capital Region of Denmark, Glostrup, 2Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 3Department of Clinical Experimental Research, Rigshospitalet, Glostrup, 4Coordinating Research Centre, Bispebjerg and Frederiksberg Hospital, Frederiksberg, 5Mental Health Centre Copenhagen, Research Unit, Mental Health Services, Capital Region of Denmark, Copenhagen, 6The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, 7Faculty of Health Sciences, University of Aarhus, Aarhus, 8Department of Public Health and Center for Healthy Aging, 9Novo Nordisk Foundation Center for Basic Metabolic Research, 10Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, 11Faculty of Medicine, Aalborg University, Aalborg, Denmark Abstract: The Danish study of Functional Disorders (DanFunD) cohort was initiated to outline the epidemiology of functional somatic syndromes (FSS) and is the first larger coordinated epidemiological study focusing exclusively on FSS. FSS are prevalent in all medical settings and can be defined as syndromes that, after appropriate medical assessment, cannot be explained in terms of a conventional medical or surgical disease. FSS are frequent and the clinical importance varies from vague symptoms to extreme disability. No well-described medical explanations exist for FSS, and how to delimit FSS remains a controversial topic. The specific aims with the cohort were to test delimitations of FSS, estimate prevalence and incidence rates, identify risk factors, delimitate the pathogenic pathways, and explore the consequences of FSS. The study population comprises a random sample of 9,656 men and women aged 18–76 years from the general population examined from 2011 to 2015. The survey comprises screening questionnaires for five types of FSS, ie, fibromyalgia, whiplash-associated disorder, multiple chemical sensitivity, irritable bowel syndrome, and chronic fatigue syndrome, and for the unifying diagnostic category of bodily distress syndrome. Additional data included a telephone-based diagnostic interview assessment for FSS, questionnaires on physical and mental health, personality traits, lifestyle, use of health care services and social factors, and a physical examination with measures of cardiorespiratory and morphological fitness, metabolic fitness, neck mobility, heart rate variability, and pain sensitivity. A biobank including serum, plasma, urine, DNA, and microbiome has been established, and central registry data from both responders and nonresponders are similarly available on morbidity, mortality, reimbursement of medicine, heath care use, and social factors. A complete 5-year follow-up is scheduled to take place from year 2017 to 2020, and further reexaminations will be planned. Several projects using the DanFunD data are ongoing, and findings will be published in the coming years. Keywords: functional somatic syndromes, medically unexplained symptoms, epidemiology, longitudinal cohort study, pathophysiology, risk factors
- Published
- 2017
14. Salt-affected soils in Tanzanian agricultural lands: Type of soils and extent of the problem
- Author
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Omar, M. M, primary, Shitindi, M. J, additional, Massawe, B. H. J, additional, Fue, K. G, additional, Meliyo, J. L, additional, and Pedersen, O, additional
- Published
- 2023
- Full Text
- View/download PDF
15. A second update on mapping the human genetic architecture of COVID-19
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Kanai, M, Andrews, S, Cordioli, M, Stevens, C, Neale, B, Daly, M, Ganna, A, Pathak, G, Iwasaki, A, Karjalainen, J, Mehtonen, J, Pirinen, M, Chwialkowska, K, Trankiem, A, Balaconis, M, Veerapen, K, Wolford, B, Ahmad, H, von Hohenstaufen Puoti, K, Boer, C, Boua, P, Butler-Laporte, G, Cadilla, C, Chwiałkowska, K, Colombo, F, Douillard, V, Dueker, N, Dutta, A, El-Sherbiny, Y, Eltoukhy, M, Esmaeeli, S, Faucon, A, Fave, M, Cadenas, I, Francescatto, M, Francioli, L, Franke, L, Fuentes, M, Durán, R, Cabrero, D, Harry, E, Jansen, P, Szentpéteri, J, Kaja, E, Kirk, C, Kousathanas, A, Krieger, J, Patel, S, Lemaçon, A, Limou, S, Lió, P, Marouli, E, Marttila, M, Medina-Gómez, C, Michaeli, Y, Migeotte, I, Mondal, S, Moreno-Estrada, A, Moya, L, Nakanishi, T, Nasir, J, Pasko, D, Pearson, N, Pereira, A, Priest, J, Prijatelj, V, Prokić, I, Teumer, A, Várnai, R, Romero-Gómez, M, Roos, C, Rosenfeld, J, Ruolin, L, Schulte, E, Schurmann, C, Sedaghati-khayat, B, Shaheen, D, Shivanathan, I, Sipeky, C, Sirui, Z, Striano, P, Tanigawa, Y, Remesal, A, Vadgama, N, Vallerga, C, van der Laan, S, Verdugo, R, Wang, Q, Wei, Z, Zainulabid, U, Zárate, R, Auton, A, Shelton, J, Shastri, A, Weldon, C, Filshtein-Sonmez, T, Coker, D, Symons, A, Aslibekyan, S, O’Connell, J, Ye, C, Hatoum, A, Agrawal, A, Bogdan, R, Colbert, S, Thompson, W, Fan, C, Johnson, E, Niazyan, L, Davidyants, M, Arakelyan, A, Avetyan, D, Bekbossynova, M, Tauekelova, A, Tuleutayev, M, Sailybayeva, A, Ramankulov, Y, Zholdybayeva, E, Dzharmukhanov, J, Kassymbek, K, Tsechoeva, T, Turebayeva, G, Smagulova, Z, Muratov, T, Khamitov, S, Kwong, A, Timpson, N, Niemi, M, Rahmouni, S, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Georges, M, Moutschen, M, Misset, B, Darcis, G, Gofflot, S, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J, Tiembe, N, Morrison, D, Afilalo, J, Mooser, V, Richards, J, Rousseau, S, Durand, M, Forgetta, V, Laurent, L, Afrasiabi, Z, Bouab, M, Tselios, C, Xue, X, Afilalo, M, Oliveira, M, St-Cyr, J, Boisclair, A, Ragoussis, J, Auld, D, Kaufmann, D, Lathrop, G, Bourque, G, Décary, S, Falcone, E, Montpetit, A, Piché, A, Renoux, C, Tremblay, K, Tse, S, Zawati, M, Davis, L, Cox, N, Below, J, Sealock, J, Shuey, M, Polikowsky, H, Petty, L, Shaw, D, Chen, H, Zhu, W, Schmidt, A, Ludwig, K, Maj, C, Rolker, S, Balla, D, Behzad, P, Nöthen, M, Fazaal, J, Keitel, V, Jensen, B, Feldt, T, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Rybniker, J, Augustin, M, Knopp, L, Kurth, I, Eggermann, T, Volland, S, Berger, M, Brenner, T, Hinney, A, Witzke, O, Konik, M, Bals, R, Herr, C, Ludwig, N, Walter, J, Latz, E, Schmidt, S, Brooks, J, Bull, S, Elliott, L, Gagnon, F, Greenwood, C, Hung, R, Lawless, J, Paterson, A, Sun, L, Rauh, M, Briollais, L, Gingras, A, Bombard, Y, Pugh, T, Simpson, J, Goneau, L, Halevy, A, Maslove, D, Borgundvaag, B, Devine, L, Bearss, E, Richardson, D, Arnoldo, S, Friedman, S, Taher, A, Stern, S, Dagher, M, Vasilevska-Ristovska, J, Biggs, C, Mickiewicz, B, Strug, L, Scherer, S, Aziz, N, Jones, S, Knoppers, B, Lathrop, M, Turvey, S, Yeung, R, Allen, U, Cheung, A, Herridge, M, Hunt, M, Lerner-Ellis, J, Taher, J, Parekh, R, Hiraki, L, Cowan, J, Ducharme, F, Ostrowski, M, Bernier, F, Kellner, J, Garg, E, Yoo, S, Vlasschaert, C, Frangione, E, Chung, M, Noor, A, Greenfeld, E, Colwill, K, Clausen, M, Chao, G, Yue, F, Fritzler, M, Whitney, J, Thiruvahindrapuram, B, Garant, J, Abraham, R, Davis, A, Campigotto, A, Papenburg, J, Niranjan, K, Betschel, S, Sadarangani, M, Barton-Forbes, M, Hanley, M, Fung, C, Lapadula, E, Macdonald, G, Puopolo, M, Kaushik, D, Nirmalanathan, K, Wong, I, Khan, Z, Zarei, N, Michalowska, M, Modi, B, Persia, P, Estacio, A, Buchholz, M, Cheatley, P, Lorenti, M, Aman, N, Matveev, V, Budylowski, P, Upton, J, Morris, S, Boyd, T, Chowdhary, S, Casalino, S, Morgan, G, Mighton, C, Mcgeer, A, Mazzulli, T, Mcleod, S, Binnie, A, Faghfoury, H, Chertkow, H, Racher, H, Serbanescu, M, 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C., Thompson, Wesley K., Fan, Chun Chieh, Johnson, Emma C., Niazyan, Lyudmila, Davidyants, Mher, Arakelyan, Arsen, Avetyan, Diana, Bekbossynova, Makhabbat, Tauekelova, Ainur, Tuleutayev, Mukhtar, Sailybayeva, Aliya, Ramankulov, Yerlan, Zholdybayeva, Elena, Dzharmukhanov, Jarkyn, Kassymbek, Kuat, Tsechoeva, Tatyana, Turebayeva, Gulsimzhan, Smagulova, Zauresh, Muratov, Timur, Khamitov, Sadyk, Kwong, Alex S. F., Timpson, Nicholas J., Niemi, Mari E. K., Rahmouni, Souad, Guntz, Julien, Beguin, Yves, Pigazzini, Sara, Nkambule, Lindokuhle, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gilles, Gofflot, Stéphanie, Bouysran, Youssef, Busson, Adeline, Peyrassol, Xavier, Wilkin, Françoise, Pichon, Bruno, Smits, Guillaume, Vandernoot, Isabelle, Goffard, Jean-Christophe, Tiembe, Nicky, Morrison, David R., Afilalo, Jonathan, Mooser, Vincent, Richards, J. 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Tsourlos, Stavros, Athanasiou, Lazaros, Kolios, Nikolaos-Gavriil, Pappa, Christiana, Papathanasiou, Alexandros, Pargana, Eleni, Nasiou, Maria, Kosmidou, Maria, Rapti, Iro, Ntotsikas, Evangelos, Chaliasos, Konstantinos, Ntzani, Evangelia, Evangelou, Evangelos, Gartzonika, Konstantina, Georgiou, Ioannis, Tzoulaki, Ioanna, Ellinghaus, David, Degenhardt, Frauke, Cáceres, Mario, Juzenas, Simonas, Lenz, Tobias L., Albillos, Agustín, Julià, Antonio, Prati, Daniele, Solligård, Erik, Garcia, Federico, Tran, Florian, Hanses, Frank, Baselli, Guido, Zoller, Heinz, Holter, Jan Cato, Fernández, Javier, Barretina, Jordi, Valenti, Luca, Bujanda, Luis, Buti, Maria, D’Amato, Mauro, Banales, Jesus M., Rosenstiel, Philip, Koehler, Philipp, Invernizzi, Pietro, de Cid, Rafael, Asselta, Rosanna, Schreiber, Stefan, Duga, Stefano, Hehr, Ute, Franke, Andre, Maya-Miles, Douglas, Hov, Johannes R., Karlsen, Tom H., Folseraas, Trine, Teles, Ana, Tanck, Anja, Gassner, Christoph, Azuure, Clinton, Wacker, Eike 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Valsecchi, Maria G., Hernandez-Tejero, María, Vehreschild, Maria J. G. T., Manunta, Maria, Acosta-Herrera, Marialbert, D’Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Marquié, Marta, Castoldi, Massimo, Cecconi, Maurizio, Tomasi, Melissa, Boada, Mercè, Joannidis, Michael, Mazzocco, Michela, Ciccarelli, Michele, Rodríguez-Gandía, Miguel, Bocciolone, Monica, Miozzo, Monica, Ayo, Natale Imaz, Blay, Natalia, Chueca, Natalia, Montano, Nicola, Martínez, Nilda, Cornely, Oliver A., Palmieri, Orazio, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Tentorio, Paolo, Castro, Pedro, Rodrigues, Pedro M., Izquierdo-Sanchez, Laura, España, Pedro Pablo, Hoffmann, Per, Bacher, Petra, de Pablo, Raúl, Ferrer, Ricard, Gualtierotti, Roberta, Gallego-Durán, Rocío, Nieto, Rosa, Carpani, Rossana, Morilla, Rubén, Badalamenti, Salvatore, Haider, Sammra, Ciesek, Sandra, Bombace, Sara, Marsal, Sara, Klein, Sebastian, Pelusi, Serena, Wilfling, Sibylle, Goerg, Siegfried, Bosari, Silvano, Brunak, Søren, Heilmann-Heimbach, Stefanie, Aliberti, Stefano, Dudman, Susanne, Zheng, Tenghao, Bahmer, Thomas, Pumarola, Tomas, Cejudo, Trinidad Gonzalez, Rimoldi, Valeria, Monzani, Valter, Skogen, Vegard, Friaza, Vicente, Andrade, Victor, Moreno, Victor, Peter, Wolfgang, Farre, Xavier, Khodamoradi, Yascha, Grimsrud, Marit M., May, Sandra, Colombo, Alicia, Virginia, Monardes-Ramírez A., Dorador, Cristina, Fuentes-Guajardo, Macarena, Silva, Andrea X., Espinosa-Parrilla, Yolanda, Yáñez, Cristian E., Retamales-Ortega, Rocío M., Saez Hidalgo, Juan M., Tobar-Calfucoy, Eduardo A., Carvajal-Silva, Laura, Martínez, Matías F., Cerpa, Leslie C., Christian, Muñoz A., Cappelli, Claudio, Valenzuela-Jorquera, Hector, Zapata-Contreras, Daniela, Zuñiga-Pacheco, Paula, Nova-Lamperti, Estefania A., Sanhueza, Sergio A., Donoso, Gerardo, Bocchieri, Pamela, Kochifas, Pia, Quiñones, Luis A., Pedersen, Ole Birger, Geller, Frank, Westergaard, David, Sequeros, Celia Burgos, Nissen, Janna, Nielsen, Susanne Dam, Feldt-Rasmussen, Ulla, Bliddal, Sofie, Grønbæk, Kirsten, Ullum, Henrik, Ostrowski, Sisse Rye, Feenstra, Bjarke, Shahin, Doaa, Sobh, Ali, Shoma, Ashraf, Nkambul, Lindokuhle, Elhadidy, Tamer A., Abd Elghafar, Mohamed S., El-Jawhari, Jehan J., Mohamed, Attia A. S., Elnagdy, Marwa H., Samir, Amr, Abdel-Aziz, Mahmoud, Khafaga, Walid T., El-Lawaty, Walaa M., Torky, Mohamed S., El-Shanshory, Mohamed R., Elzeiny, Ahmed, Rashad, Amal, Mansour, Tamer A., Yassen, Amr M., Hegazy, Mohamed A. F., Okasha, Kamal, Eid, Mohammed A., Hanteera, Moahmed S., Medina-Gomez, Carolina, Ikram, M. Arfan, Uitterlinden, Andre G., Ripatti, Samuli, Jermy, Bradley, Ruotsalainen, Sanni, Kristiansson, Kati, Koskelainen, Sami, Perola, Markus, Donner, Kati, Kivinen, Katja, Palotie, Aarno, Kaunisto, Mari, Julienne, Hanna, Aschard, Hugues, Deleuze, Jean-Francois, Debette, Stephanie, Tregouet, David-Alexandre, Abel, Laurent, Henches, Léo, Lefloch, Edith, Claire, Dandine-Roulland, Sakuntabhai, Anavaj, Bourgeron, Thomas, Olaso, Robert, Daian, Delphine Bacq, Pellegrin, Isabelle, Casanova, Jean-Laurent, Cobat, Aurélie, Jouanguy, Emmanuelle, Zhang, Qian, Ghosn, Jade, Mentré, France, Laouénan, Cédric, Tubiana, Sarah, Chirouze, Catherine, Quintana-Murci, Luis, Patin, Etienne, Duffy, Darragh, Boland, Anne, Carreras, Anna, Galván-Femenía, Iván, Farré, Xavier, Cortés, Beatriz, Mercader, Josep Maria, Guindo-Martinez, Marta, Torrents, David, Garcia-Aymerich, Judith, Castaño-Vinyals, Gemma, Dobaño, Carlota, van Heel, David A., Hunt, Karen A., Trembath, Richard C., Jacobs, Benjamin Meir, Huang, Qin Qin, Martin, Hilary C., Mason, Dan, Trivedi, Bhavi, Wright, John, Munisamy, Malathy, Finer, Sarah, Griffiths, Christopher J., McCarthy, Mark I., Rosenberger, Carrie, Lee, Jong Eun, Chang, Diana, Hammer, Christian, Hunkapiller, Julie, Mahajan, Anubha, Pendergrass, Rion, Sucheston-Campbell, Lara, Yaspan, Brian, Lee, Hyun Soo, Shin, Eunsoon, Jang, Hye Yoon, Kim, Sunmie, Kym, Sungmin, Kim, Yeon-Sook, Jeong, Hyeongseok, Kwon, Ki Tae, Kim, Shin-Woo, Kim, Jin Yong, Jang, Young Rock, Kim, Hyun ah, Lee, Ji yeon, Lee, Jeong Eun, Lee, Shinwon, Choe, Kang-Won, Kang, Yu Min, Jee, Sun Ha, Jung, Keum Ji, Park, Hyun-Young, Kim, Bong-Jo, Kim, Young Jin, Hwang, Mi Yeong, Yoon, Kyungheon, Pairo-Castineira, Erola, Rawlik, Konrad, Caulfield, Mark J., Baillie, J. Kenneth, Griffiths, Fiona, Bretherick, Andrew D., Stuckey, Alex, Odhams, Christopher A., Walker, Susan, Russell, Clark D., Malinauskas, Tomas, Wu, Yang, Shen, Xia, Elliott, Katherine S., Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Fawkes, Angie, Murphy, Lee, Vitart, Veronique, Wilson, James F., Yang, Jian, Scott, Richard H., Moutsianas, Loukas, Law, Andy, Begg, Colin, Hendry, Sara Clohisey, Hinds, Charles, Horby, Peter, Knight, Julian, Ling, Lowell, Maslove, David, McAuley, Danny, Millar, Johnny, Montgomery, Hugh, Nichol, Alistair, Openshaw, Peter J. M., Ponting, Chris P., Rowan, Kathy, Semple, Malcolm G., Shankar-Hari, Manu, Summers, Charlotte, Walsh, Timothy, Pan, Jacqueline, Grau, Neus, Jones, Tim Owen, Lim, Rosario, Marotti, Martina, Whitton, Christopher, Bociek, Aneta, Campos, Sara, Arbane, Gill, Ostermann, Marlies, Cha, Mina, DAmato, Fabiola, Kosifidou, Eirini, Lorah, Shelley, Morera, Kyma, Brady, Laura, Hugill, Keith, Henning, Jeremy, Bonner, Stephen, Headlam, Evie, Jones, Jessica, List, Abigail, Morley, Joanne, Welford, Amy, Kamangu, Bobette, Ratnakumar, Anitha, Shoremekun, Abiola, Alldis, Zoe, Astin-Chamberlain, Raine, Bibi, Fatima, Biddle, Jack, Blow, Sarah, Bolton, Matthew, Borra, Catherine, Bowles, Ruth, Burton, Maudrian, Choudhury, Yasmin, Cox, Amber, Easthope, Amy, Ebano, Patrizia, Fotiadis, Stavros, Gurasashvili, Jana, Halls, Rosslyn, Hartridge, Pippa, Kallon, Delordson, Kassam, Jamila, Lancoma-Malcolm, Ivone, Matharu, Maninderpal, May, Peter, Mitchelmore, Oliver, Newman, Tabitha, Patel, Mital, Pheby, Jane, Pinzuti, Irene, Prime, Zoe, Prysyazhna, Oleksandra, Shiel, Julian, Taylor, Melanie, Tierney, Carey, Zongo, Olivier, Wood, Suzanne, Zak, Anne, Collier, David, Mundy, Manuela, Thompson, Christopher, Pritchard, Lisa, Gellamucho, Minnie, Cartlidge, David, Bandla, Nageswar, Bailey, Lucy, Davies, Michelle, Delaney, Jane, Scott, Leanne, Abdelrazik, Marwa, Alasdair, Frater, Carter, David, Elhassan, Munzir, Ganesan, Arunkumar, Jenkins, Samuel, Lamond, Zoe, Purohit, Dharam, Rohit, Kumar, Saleem, Malik, Wall, Alanna, Xavier, Kugan, Bakthavatsalam, Dhanalaksmi, Gehad, Kirolos, Gnanapragasam, Pakeerathan, Jain, Kapil, Jain, Swati, Malik, Abdul, Pappachan, Naveen, Moreno-Cuesta, Jeronimo, Haldeos, Anne, Vincent, Rachel, Oziegb, Maryjane, Cavazza, Anna, Cockrell, Maeve, Corcoran, Eleanor, Depante, Maria, Finney, Clare, Jerome, Ellen, Knighton, Abigail, Nayak, Monalisa, Pappa, Evita, Saha, Rohit, Saha, Sian, Dodd, Andrew, O’Reilly, Kevin, McPhail, Mark, Clarey, Emma, Noble, Harriet, Smith, John, Coghlan, Phoebe, Brett, Stephen, Gordon, Anthony, Templeton, Maie, Antcliffe, David, Banach, Dorota, Darnell, Sarah, Fernandez, Ziortza, Jepson, Eleanor, Mohammed, Amal, Rojo, Roceld, Arias, Sonia Sousa, Gurung, Anita Tamang, Wong, Jenny, Fernandez-Roman, Jaime, Hamilton, David O., Johnson, Emily, Johnston, Brian, Martinez, Maria Lopez, Mulla, Suleman, Waite, Alicia A. C., Williams, Karen, Waugh, Victoria, Welters, Ingeborg, Emblem, Jessica, Norris, Maria, Shaw, David, Bashyal, Archana, Beer, Sally, Hutton, Paula, McKechnie, Stuart, Davidson, Neil, Mathew, Soya, Readion, Grace, Ryu, Jung, Wilson, Jean, Agrawal, Shruti, Elston, Kay, Jones, Megan, Meaney, Eoghan, Polgarova, Petra, Elbehery, Muhammad, Daubney, Esther, Ng, Anthony, Marshall, Jocelyn, Pathan, Nazima, Stroud, Katerina, White, Deborah, Andrew, Angela, Ashraf, Saima, Clark, Amy, Dent, Martin, Langley, Margaret, Peters, Cecilia, Ryan, Lucy, Sampson, Julia, Wei, Shuying, Baddeley, Alice, Meredith, Megan, Morris, Lucy, Gibbons, Alexandra, McLoughlin, Lisa, Delgado, Carlos Castro, Clark, Victoria, Dawson, Deborah, Ding, Lijun, Durrant, Georgia, Ezeobu, Obiageri, Harrison, Abiola, Hurt, William James, Kanu, Rebecca, Kinch, Ashley, Leaver, Susannah, Lisboa, Ana, Mathew, Jisha, Patel, Kamal, Saluzzio, Romina Pepermans, Rawlins, John, Samakomva, Tinashe, Shah, Nirav, Sicat, Christine, Texeira, Joana, Queiroz, Joana Gomes De, Gloria, Edna Fernandes Da, Maccacari, Elena, Yun, Nikki, Manna, Soumendu, Farnell-Ward, Sarah, Maizcordoba, Maria, Thanasi, Maria, Ali, Hawakin Haji, Hastings, Janice, Grauslyte, Lina, Hussain, Musarat, Ruge, Bobby, King, Sam, Pogreban, Tatiana, Rosaroso, Lace, Smith, Helen, Phull, Mandeep-Kaur, Adams, Nikkita, Franke, George, George, Aparna, Salciute, Erika, Wong, Joanna, Dunne, Karen, Flower, Luke, Sharland, Emma, Sra, Sukhmani, Andrew, Gillian, Callaghan, Marie, Barclay, Lucy, Marshall, Lucy, Amamio, Maria, Birch, Sophie, Briton, Kate, Clark, Sarah, Doverman, Katerine, Hope, Dave, Mcculloch, Corrienne, Simpson, Scott, Singleton, Jo, Fernandez, Rita, Allen, Meryem, Baptista, David, Crowe, Rebecca, Fox, Jonathan, Khera, Jacyntha, Loveridge, Adam, McKenley, India, Morino, Eriko, Naranjo, Andres, O’Connor, Denise, Simms, Richard, Sollesta, Kathryn, Swain, Andrew, Venkatesh, Harish, Herdman-Grant, Rosie, Joseph, Anna, Nown, Angela, Rose, Steve, Pogson, David, Boxall, Helen, Brimfield, Lutece, Claridge, Helen, Daly, Zoe, George, Shenu, Gribbin, Andrew, Cheema, Yusuf, Cutler, Sean, Richards, Owen, Roynon-Reed, Anna, Cherian, Shiney, Heron, Anne Emma, Williams, Gemma, Szakmany, Tamas, Waters, Abby, Collins, Kim, Dunhill, Jill, Jones, Ffion, Morris, Rebecca, Ship, Lucy, Cardwell, Amy, Ali, Syamlan, Bhatterjee, Ravi, Bolton, Rachel, Chukkambotla, Srikanth, Coleman, Dabheoc, Dalziel, Jack, Dykes, Joseph, Fine, Christopher, Gay, Bethan, Goddard, Wendy, Goodchild, Drew, Harling, Rhiannan, Hijazi, Muhammad, Keith, Sarah, Khan, Meherunnisa, Matt, Roseanna, Ryan-Smith, Janet, Saad, Samuel, Springle, Philippa, Thomas, Jacqueline, Truman, Nick, Kazi, Aayesha, Smith, Matthew, Collier, Heather, Davison, Chloe, Duberley, Stephen, Hargreaves, Jeanette, Hartley, Janice, Patel, Tahera, Smith, Ellen, Kent, Alissa, Goodwin, Emma, Zaki, Ahmed, Tibke, Clare, Hopkins, Susan, Gerrard, Hywel, Jackson, Matthew, Bennett, Sara, Marsh, Liane, Mills, Rebecca, Bell, Jessica, Campbell, Helen, Dawson, Angela, Dodds, Steve, Duffy, Stacey, Gallagher, Lisa, McCafferty, Gemma, Short, Stacey, Smith, Tracy, Thomas, Kirsty, Walker, Claire, Reynolds, Jessica, Yates, Bryan, McKie, Hayley, Panteli, Maria, Thompson, Maria, Waddell, Gail, Beger, Sarah De, Abraheem, Azmerelda, Dunmore, Charlie, Girach, Rumanah, Jones, Rhianna, London, Emily, Nagra, Imrun, Nasir, Farah, Sainsbury, Hannah, Smedley, Clare, Brearey, Stephen, Burchett, Caroline, Cawley, Kathryn, Faulkner, Maria, Jeffrey, Helen, Bamford, Peter, Shaikh, Firdaus, Slack, Lauren, Davies, Angela, Brooke, Hollie, Suarez, Jose Cebrian, Charlesworth, Ruth, Hansson, Karen, Norris, John, Poole, Alice, Sandhu, Rajdeep, Smithson, Elizabeth, Thirumaran, Muthu, Wagstaff, Veronica, Buckley, Sarah, Sloan, Brendan, Rose, Alastair, Major, Amy, Metcalfe, Alexandra, Almaden-Boyle, Christine, Austin, Pauline, Chapman, Susan, Eros, Alexandre, Cabrelli, Louise, Cole, Stephen, Whyte, Clare, Casey, Matt, Bafitis, Vasileios, Tsinaslanidis, George, George, Cassandra, Khade, Reena, Black, Christopher, Ashok, Sundar Raj, Farley, Sean, Brinkworth, Elaine, Harford, Rachel, Murphy, Carl, Williams, Marie, Newey, Luke, Toghill, Hannah, Lewis, Sophie, Rees, Tabitha, Battle, Ceri, Baker, Mark, Travers, Jenny, Chesters, Karen, Baxter, Nicola, Arnott, Andrew, McCreath, Gordan, McParland, Christopher, Rooney, Laura, Sim, Malcolm, Henderson, Steven, Abel, Lynn, Dalton, Carol, Kennedy-Hay, Sophie, O’Donohoe, Lynn, O’Hare, Megan, Orlikowska, Izabela, Parker, Natasha, McNeela, Fiona, Lyle, Amanda, Hughes, Alistair, Radhakrishnan, Jayachandran, Gibson, Sian, Bancroft, Hollie, Bellamy, Mary, Daglish, Jacqueline, Kadiri, Salma, Moore, Faye, Rhodes, Joanne, Sangombe, Mirriam, Peterkin, Zhane, Scriven, James, Carmody, Margaret, Cottle, Juliet, Peasgood, Emily, de Gordoa, Laura Ortiz-Ruiz, Phillips, Claire, Skinner, Denise, Cinquina, Zoe, Howard, Kate, Joy, Rosie, Roche, Samantha, Birkinshaw, Isobel, Carter, Joseph, Ingham, Jo, Marshall, Nicola, Pearson, Harriet, Scott, Zoe, Dasgin, Jo, Gill, Jaspret, Nilsson, Annette, Bamford, Amy, Hull, Diana, Ahmadhaider, Nafeesah, Bates, Michelle, McGhee, Christopher, Ellis, Hannah, Howe, Gwenllian Sera, Singh, Jayaprakash, Stroud, Natalie, Roche, Lisa, Lynch, Ceri, Deacon, Bethan, Pothecary, Carla, Smeaton, Justyna, Agravante, Kevin, Krishnamurthy, Vinodh, Diaba, Cynthia, John, Lincy, Lim, Lai, Jha, Rajeev, Egan, Jasmine, Felton, Timothy, Glasgow, Susannah, Padden, Grace, Choudhr, Ozerah, Bradley-Potts, Joanne, Moss, Stuart, Lingeswaran, Saejohn, Alexander, Peter, Brandwood, Craig, Fiouni, Sofia, Ward, Luke, Allen, Schvearn, Shaw, Jane, Smith, Christopher, Adanini, Oluronke, Collins, Rebecca, Msiska, Maines, Ofori, Linda, Bhatia, Nikhil, Dolan, Hayley, Brunton, Mark, Caterson, Jess, Coles, Holly, Keating, Liza, Tilney, Emma, Jacques, Nicola, Frise, Matthew, Armistead, Jennifer, Bartley, Shauna, Bhuie, Parminder, Rai, Sabi, Tomkova, Gabriela, Greer, Sandra, Shuker, Karen, Tridente, Ascanio, Dobson, Emma, Hunt, Jodie, Tully, Redmond, Dearden, Joy, Drummond, Andrew, Kamath, Prakash, Bullock, Emily, Mulcahy, Michelle, Munt, Shelia, O’Connor, Grainne, Philbin, Jennifer, Rishton, Chloe, Scott, Chloe, Winnard, Sarah, Hasni, Nurkamalia, Gascoyne, Rachel, Hawes, Joanne, Pritchard, Kelly, Stevenson, Lesley, Whileman, Amanda, Beavis, Sarah, Bishop, Lauren, Cart, Cindy, Dale, Katie, Kelly-Baxter, Mary, Mendelski, Adam, Moakes, Emma, Smith, Rheanna, Woodward, Jan, Wright, Stephanie, Allan, Angela, Botello, Adriana, Liew, Jade, Medhora, Jasmine, Trumper, Erin, Savage, Felicity, Scott, Teresa, Place, Marc, Kaye, Callum, Benyon, Sarah, Marriott, Suzie, Park, Linda, Quinn, Helen, Skyes, Daisy, Zitter, Lily, Baines, Kizzy, Gordon, Elizabeth, Keenan, Samantha, Pitt, Andrew, Duffy, Katharine, Ireland, Jane, Semple, Gary, Turner, Lynne, Cathcart, Susanne, Rimmer, Dominic, Puxty, Alex, Puxty, Kathryn, Hurst, Andrew, Miller, Jennifer, Speirs, Susan, Walker, Lauren, Bradshaw, Zena, Brown, Joanna, Melling, Sarah, Preston, Stephen, Slawson, Nicola, Warden, Scott, Beasley, Alanna, Stoddard, Emma, Benham, Leonie, Cupitt, Jason, Caswell, Melanie, Elawamy, Lisa, Wignall, Ashleigh, Roberts, Belinda, Golding, Hannah, Leggett, Samantha, Male, Michelle, Marani, Martyna, Prager, Kirsty, Williams, Toran, Golder, Kim, Jones, Oliver, Cusack, Rebecca, Bolger, Clare, Burnish, Rachel, Carter, Michael, Jackson, Susan, Salmon, Karen, Biss, Jonathan, Aquino, Maia, Croft, Maria, Frost, Victoria, White, Ian, Govender, Keshnie, Webb, Natasha, Stapleton, Liana, Wells, Colin, Nikitas, Nikitas, Sanchez - Rodriguez, Ana, Spencer, Kayleigh, Stowe, Bethan, Izzard, Yvonne, Poole, Michelle, Monnery, Sonja, Trotman, Sallyanne, Beech, Valerie, Combes, Edward, Joefield, Teishel, Covernton, Patrick, Savage, Sarah, Woodward, Elizabeth, Camsooksai, Julie, Reschreiter, Henrik, Barclay, Charlotte, DeAth, Yasmin, Dube, Judith, Humphrey, Charlotte, Jenkins, Sarah, Langridge, Emma, Milne, Rebecca, Wadams, Beverley, Woolcock, Megan, Brett, Michael, Digby, Brian, Gemmell, Lisa, Hornsby, James, MacGoey, Patrick, O’Neil, Pauline, Price, Richard, Sundaram, Radha, Rodden, Natalie, Thomson, Nicola, Rooney, Kevin, Currie, Susan, Henderson, Philip, Ogg, Bethan, Whiteley, Simon, Wilby, Liz, Long, Kate, Matthew, Shailamma, Salada, Sheila, Trott, Susan, Watts, Sarah, Friar, Zoe, Speight, Abigail, Bastion, Victoria, Chandna, Humza, Djeugam, Brice, Haseeb, Muhammad, Kent, Harriet, Lubimbi, Gamu, Murdoch, Sophie, Thomas, Alastair, David, Beena, Lorusso, Rachel, Vochin, Ana, Penacerrada, Melchizedek, Wulandari, Retno, Heath, Charlotte, Jakkula, Srinivas, Morris, Anna, Ahmed, Ashar, Nune, Arvind, Buttriss, Claire, Whitaker, Emma, Davey, Miriam, Golden, David, Acklery, Amy, Fernandes, Fabio, Seaman, Bec, Earl, Victoria, Collins, Amy, Khaliq, Waqas, Adam, Rachel, Treus, Estefania, Holland, Sarah, Alfonso, Jordan, Blackledge, Bethan, Bruce, Michelle, Durrans, Laura Jayne, Eltayeb, Ayaa, Harris, Jade, Hey, Samuel, Hruska, Martin, Lamb, Thomas, Rothwell, Joanne, Fitzgerald, Adele, Lindergard, Gabriella, T-Michael, Helen, Duncan, Tracey, Baxter-Dore, Sharon, Cooper, Lisa, Fox, Claire, Guerin, Jacinta, Hodgkiss, Tracey, Connolly, Karen, McAlinden, Paul, Bridgett, Victoria, Fearby, Maggie, Gulati, A., Hanson, Helen, Kelly, Sinead, McCormack, Louise, Nixon, Rachel, Robinson, Philip, Slater, Victoria, Stephenson, Elaine, Webster, Andrea, Webster, K., Hays, Carole, Hudson, Anne, Patel, Bijal, Clement, Ian, Davis, John, Francis, Sarah, Jerry, Douglas, Abernathy, Caroline, Foster, Louise, Gratrix, Andrew, Cabral-Ortega, Llucia, Hines, Matthew, Martinson, Victoria, Stones, Elizabeth, Winter, Karen, Barrow, Esther, Wylie, Katharine, Baines, Deborah, Birchall, Katie, Kolakaluri, Laurel, Clark, Richard, Sukumaran, Anila, Barker, Melanie, Paripoorani, Deborah, Smith, Lara, Taylor, Charlotte, Downes, Charlotte, Hayman, Melanie, Riches, Katie, Daniel, Priya, Subramanian, Deepak, Holding, Kathleen, Hilton, Mary, Mcdonald, Carly, Richardson, Georgina, Halladay, Georgia, Harding, Peter, Reddy, Amie, Turner-Bone, Ian, Wilding, Laura, Parker, Robert, Lloyd, Michaela, Smith, Leanne, Kelly, Charlie, Lazo, Maria, Neal, Alan, Walton, Olivia, Melville, Julie, Naisbitt, Jay, Joseph, Rosane, Callam, Sara, Hudig, Lisa, Keshet-Price, Jocelyn, Stammers, Katie, Convery, Karen, Randell, Georgina, Fottrell-gould, Deirdre, Mwaura, Esther, Sutherland, Sara-Beth, Stewart, Richard, Mew, Louise, Wren, Lynn, Thrasyvoulou, Laura, Willis, Heather, Hopkins, Bridget, Lenton, Daniel, Roberts, Abigail, Bokhari, Maria, Lucas, Rachael, McCormick, Wendy, Ritzema, Jenny, Linnett, Vanessa, Sanderson, Amanda, Wild, Helen, Flanagan, Rebecca, Hull, Robert, Rhead, Kat, McKenna, Emma, Hughes, Gareth, Anderson, Jennifer, Jones, Kelly, Latham, Scott, Riley, Heather, Coulding, Martina, Clark, Martyn, McCormick, Jacqueline, Mercer, Oliver, Potla, Darsh, Rehman, Hafiz, Savill, Heather, Turner, Victoria, Jude, Edward, Kilroy, Susan, Apetri, Elena, Basikolo, Cathrine, Catlow, Laura, Collis, Matthew, Doonan, Reece, Harvey, Alice, Knowles, Karen, Lee, Stephanie, Lomas, Diane, Lyons, Chloe, McMorrow, Liam, Michael, Angiy, Pendlebury, Jessica, Perez, Jane, Poulaka, Maria, Proudfoot, Nicola, Slevin, Kathryn, Thomas, Vicky, Walker, Danielle, Dark, Paul, Charles, Bethan, McLaughlan, Danielle, Slaughter, Melanie, Horner, Dan, Marsden, Tracy, Andrews, Joyann, Beech, Emily, Akinkugbe, Olugbenga, Bamford, Alasdair, Belfield, Holly, Jones, Gareth A. L., McHugh, Tara, Meghari, Hamza, Ray, Samiran, Tomas, Ana Luisa, O’Neill, Lauran, Peters, Mark, Bell, Michael, Benkenstein, Sarah, Chisholm, Catherine, Davies, Charlene, Kupiec, Klaudia, Payne, Caroline, Halls, Joanna, Blakemore, Hayley, Goff, Elizabeth, Hayes, Kati, Smith, Kerry, Stephens, Deanna, Worner, Ruth, Borislavova, Borislava, Faulkner, Beverley, Thomas, Matt, Cookson, Ruth, Gendall, Emma, Larman, Georgina, Pope, Rebecca, Smalira, Artur, Priestley, Victoria, Cosier, Tracey, Millen, Gemma, Rand, James, Schumacher, Natasha, Sandhar, Roxana, Weston, Heather, Richardson, Neil, Cooper, Lucy, Jones, Cathy, Huang, Ya-Wen Jessica, Jacob, Reni, Denmade, Craig, Mcintyre, Lewis, Trodd, Dawn, Martin, Jane, Watson, Geoff, Bevan, Emily, Wreybrown, Caroline, Bano, Shereen, Bellwood, Ruth, Bentley, Michael, Bromley, Matt, Gurr, Lucy, Ledgard, Camilla, McGowan, Janet, Pye, Kate, Sellick, Kirsten, Stacey, Amelia, Warren, Deborah, Wilkinson, Brian, Akeroyd, Louise, Shafique, Huma, Morgan, James, Shorter, Susan, Swinger, Rachel, Waters, Emily, Lawton, Tom, Allan, Elizabeth, Darlington, Kate, Davies, Ffyon, Davies, Llinos, Easton, Jack, Kumar, Sumit, Lean, Richard, Mackay, Callum, Pugh, Richard, Qiu, Xinyi, Rees, Stephanie, Scanlon, Jeremy, Lewis, Joanne, Menzies, Daniel, Bolger, Annette, Davies, Gwyneth, Davies, Jennifer, Garrod, Esther, Jones, Helen, Manley, Rachel, Williams, Hannah, Frankham, Jordan, Pitts, Sally, White, Nigel, Branney, Debbie, Tiller, Heather, Efford, Georgia, Garland, Zoe, Grimmer, Lisa, Gumbrill, Bethany, Johnson, Rebekah, Sweet, Katie, Bewley, Jeremy, Coleman, Christina, Corcoran, Katie, Morano, Eva Maria Hernandez, Shiel, Rachel, Webster, Denise, Bonnici, Josephine, Daniel, Eleanor, Dell, Abbie, Kent, Melanie, Wilkinson, Ami, Brown, Ellen, Kay, Andrea, Campbell, Suzanne, Cowton, Amanda, Birt, Mark, Greenaway, Vicki, Potts, Kathryn, Hutton, Clare, Shepperson, Andrew, Forsey, Miranda, Nicholson, Alice, Vertue, Mark, Riches, Joanne, Kaliappan, Agilan, Nicholson, Anne, MacCallum, Niall, Raith, Eamon, Bercades, Georgia, Hass, Ingrid, Brealey, David, Martir, Gladys, Reyes, Anna, Smyth, Deborah, Zapatamartinez, Maria, Alvaro, Ana, Jetha, Champa, Ma, Louise, Booker, Lauren, Mostoles, Loreta, Pratley, Anezka, Altabaibeh, Abdelhakim, Parmar, Chetan, Gilbert, Kayleigh, Ferguson, Susie, Shepherd, Amy, Morris, Sheila, Baruah, Rosie, Lloyd, Georgina, Bell, Stephanie, Rivers, Vanessa, Purewal, Bally, Hammerton, Kate, Anderson, Susan, Birch, Janine, Collins, Emma, Oleary, Ryan, Cornell, Sarah, Jarmain, Jordan, Rogerson, Kimberley, Wakinshaw, Fiona, Woods, Lindsey, Rostron, Anthony, Elcioglu, Zeynep, Roy, Alistair, Bell, Gillian, Dickson, Holly, Wilcox, Louise, Katary, Amro, English, Katy, Hutter, Joanne, Pawley, Corinne, Doble, Patricia, Shovelton, Charmaine, Vaida, Marius, Purnell, Rebecca, Thomas, Ashly, Cagova, Lenka, Fofano, Adama, Holcombe, Helen, Mitchell, Alice Michael, Mwaura, Lucy, Praman, KrithivasanÂ, Garnr, Lucie, Mepham, Sue, Paques, Kitty, Vuylsteke, Alain, Mackie, Jennifer, Pearn, Carmen, Zamikula, Julie, Nyirenda, Maggie, Capozzi, Lisa, Reece-Anthony, Rosie, Noor, Hazma, Nilo, Alfa Cresia, Grove, Michelle, Daniel, Amelia, Finn, Joanne, White, Nikki, Saha, Rajnish, Badal, Bibi, Ixer, Karen, Duffin, Donna, Player, Ben, Hill, Helen, Cole, Jade, Brooks, Jenny, Davies, Rhys, Hunt, Lauren, Thomas, Emma, Williams, Angharad, Oblak, Metod, Thankachen, Mini, Irisari, Jamie, Sayan, Amrinder, Popescu, Monica, Finch, Cheryl, Jamieson, Andrew, Quinn, Alison, Cooper, Joshua, Liderth, Sarah, Waddington, Natalia, Burn, Iona, Manso, Katarina, Penn, Ruth, Tebbutt, Julie, Thornton, Danielle, Winchester, James, Hambrook, Geraldine, Shanmugasundaram, Pradeep, Craig, Jayne, Simpson, Kerry, Higham, Andrew, Sibbett, Louise, Paine, Sheila, Reed, Annabel, Conyngham, Jo-Anna, Mupudzi, Mcdonald, Thomas, Rachel, Wright, Mary, Griffin, Denise, Partridge, Richard, Corral, Maria Alvarez, Muchenje, Nycola, Sitonik, Mildred, Butler, Aaron, Folkes, Linda, Fox, Heather, Gardner, Amy, Helm, David, Hobden, Gillian, King, Kirsten, Margalef, Jordi, Margarson, Michael, Martindale, Tim, Meadows, Emma, Raynard, Dana, Thirlwall, Yvette, Baird, Yolanda, Gomez, Raquel, Martin, Darren, Hodgson, Luke, Corin, Clinton, Sidall, Erikka, Szabo, Densie, Floyd, Sharon, Davies, Hannah, Austin, Karen, Kelsall, Olivia, Wood, Hannah, Cornell, Thomas, Ralph, Kate, Bean, Sarah, Burt, Karen, Spivey, Michael, Richards, Carol, Tedstone, Rachel, Carmody, Siobhain, Zhao, Xiaobei, Page, Valerie, Guanco, Mark Louie, Hoxha, Elvira, Zorloni, Camilla, Dean, Charlotte, Jones, Emma, Carter, Emma, Dunn, Joshua, Kong, Thomas, Mahenthran, Mervin, Marsh, Chris, Holland, Maureen, Keenan, Natalie, Mahmoud, Mohamed, Lyons, Marc, Wassall, Helen, Young, Meghan, Bradley, Paul, Burda, Dorota, Donlon, Sinead, Harden, Lesley, Harris, Celia, Mayangao, Irving, Montaser, Rugia, Mtuwa, Sheila, Piercy, Charles, Smith, Eleanor, Stone, Sarah, Verula, Jerik, Blackman, Helen, Marriott, Cheryl, Michalak, Natalia, Creagh-Brown, Ben, Salberg, Armorel, Boyer, Naomi, Pristopan, Veronika, Maynard, Victoria, Walker, Rachel, Hormis, Anil, Collier, Dawn, Graham, Cheryl, McCormick, Jake, Warrington, Jake, Cosgrove, Denise, McFarland, Denise, Ratcliffe, Judith, Charnock, Rob, Wynter, Inez, Gill, Mandy, Kirk, Jill, Paul, Paul, Ratnam, Valli, Shelton, Sarah, Jardine, Catherine, Hay, Alasdair, Williams, Dewi, Durga, Latha, Hibbert, Meg, Kennard-Holden, Gareth, Woodford, Chrsitopher, Tetla, Dariusz, Price, Alicia, Thomas, Alice, Thorpe, Chris, Knights, Ellen, Ward, Donna, Laha, Shondipon, Verlander, Mark, Williams, Alexandra, Prout, Rachel, Langton, Helen, Watters, Malcolm, Hunt, Charlotte, Novis, Catherine, Arif, Sarwat, Cunningham, Amy, Hewitt, Claire, Hindale, Julia, Jackson-Lawrence, Karen, Shepardson, Sarah, Wills, Maryanne, Butler, Susie, Tavares, Silivia, Barber, Russell, Hilldrith, Annette, Hubbard, Kelly, Egginton, Dawn, Clark, Michele, Purvis, Sarah, Sinclair, Simon, Collins, Vicky, Landeg, Bethan, Sell, Craig, Coetzee, Samantha, Gales, Alistair, Otahal, Igor, Icke, Becky, Raj, Meena, Williams, Caroline, Williams, Jill, Hill, Lucy, Kayani, Abdul, Masunda, Bridgett, Gondo, Prisca, Atayeva, Nigara, Cruz, Carina, Pattison, Natalie, Burnett, Caroline, Hatton, Jonathan, Heeney, Elaine, Newton, Maria, Al-Moasseb, Hassan, Behan, Teresa, Player, Jasmine, Stead, Rachael, Mitra, Atideb, Nauyokas, Kirsty, Humphreys, Sally, Cockerill, Helen, Tampsett, Ruth, Postovalova, Evgeniya, Coventry, Tina, McGregor, Amanda, Fowler, Susan, Macmahon, Mike, Cochrane, Patricia, Pirie, Sandra, Hanley, Sarah, Ali, Asifa, Brady, Megan, Dale, Sam, Dance, Annalisa, Gledhill, Lisa, Greig, Jill, Hanson, Kathryn, Holdroyd, Kelly, Home, Marie, Ishaq, Tahira, Kelly, Diane, Matapure, Lear, Melia, Deborah, Mellor, Samantha, Merwaha, Ekta, Nortcliffe, Tonicha, Shaw, Lisa, Shaw, Ryan, Wood, Tracy, Bayo, Lee-Ann, Usher, Miranda, Wilson, Alison, Kitson, Ross, Pinnell, Jez, Robinson, Matthew, Boltwood, Kaitlin, Birch, Jenny, Bough, Laura, Tutton, Rebecca, Winter-Goodwin, Barbara, Goodsell, Josie, Taylor, Kate, Williams, Patricia, Williams, Sarah, Cave, Ashleigh, Rees, James, Imeson-Wood, Janet, Smith, Jacqueline, Amin, Vishal, Karthik, Komala, Kausar, Rizwana, Anastasescu, Elena, Reid, Karen, Anumakonda, Vikram, Stoddart, Ella, Demetriou, Carrie, Eckbad, Charlotte, Howie, Lucy, Mitchard, Sarah, Ramos, Lidia, White, Katie, Hierons, Sarah, Kelly, Fiona, Serrano-Ruiz, Alfredo, Evans, Gabrielle, Nicol, Liz, Wilkins, Joy, Hulacka, Kim, Debreceni, Gabor, Brown, Alison, Crickmore, Vikki, Hill, Kay, Kannan, Thogulava, Dagutao, Zenaida, Beesley, Kate, Lewis, Alison, Perry, Jess, Antony, Sherly, Board, Sarah, Buckley, Clare, Pippard, Lucy, Tanate, Alfonso, Wood, Diane, Kubisz-Pudelko, Agnieska, Gouda, Ayman, Auld, Fiona, Donnachie, Joanne, Murdoch, Euan, Prentice, Lynn, Runciman, Nikole, Senaratne, Dhaneesha, Short, Abigail, Sweeney, Laura, Symon, Lesley, Todd, Anne, Turner, Patricia, McCann, Erin, Salutous, Dario, Edmond, Ian, Whitelaw, Lesley, Bland, Yvonne, Kajtor, Istvan, Kavanagh, Lisa, Singler, Karen, Linfield-Brown, George, Moore, Luke Stephen Prockter, Vizcaychipi, Marcela, Martins, Laura, Moore, Luke, Bull, Rhian, Carungcong, Jaime, Allen, Louise, Beranova, Eva, Knight, Alicia, Price, Carly, Tilbey, Sorrell, Turney, Sharon, Hazelton, Tracy, Tutt, Gabriella, Arora, Mansi, Turki, Salah, Sinfield, Emily, Deery, Joanne, Ramos, Hazel, Cristiano, Daniele, Dormand, Natalie, Farzad, Zohreh, Gummadi, Mahitha, Salmi, Sara, Sloane, Geraldine, Varghese, Mathew, Thwaites, Vicky, Patel, Brijesh, Kamal, Liyanage, Zborowski, Anelise Catelan, Coe, Ryan, Anderson, Madeleine, Beadle, Jane, Coates, Charlotte, Collins, Katy, Crowley, Maria, Johnson, Laura, King, Laura, Paramsothy, Remi, Sargeant, Janet, Silva, Pedro, Stuart, Carmel, Taylor, June, Tyl, David, Wakefield, Phillipa, Kamundi, Charlotte, Olufuwa, Olumide, Belagodu, Zakaulla, Gherman, Anca, Oakley, Naomi, Allan, John, Geary, Tim, Meikle, Alistair, O’Brien, Peter, Wood, Stephen, Clark, Andrew, Houston, Gordon, Black, Karen, Clarkson, Michelle, D’Sylva, Stuart, Morrison, Alan, Norman, Kathryn, Taylor, Margaret, Clements, Suzanne, Cohrane, Catriona, Gonzalez, Nora, Strachan, Dominic, Beith, Claire, Moar, Kirsten, Anderson, Peter, Archer, Katie, Burtenshaw, Andrew, Clayton, Sarah, Cother, Naiara, Cowley, Nicholas, Davis, Caroline, Digby, Stephen, Durie, Alison, Harrison, Alison, Low, Emma, McAlindon, Michael, McCurdy, Alex, Morgan, Aled, Rankin, Tobias, Thrush, Jessica, Tranter, Helen, Vigurs, Charlie, Wild, Laura, Murphy, Lorna, Smythe, Michelle, Brickell, Kathy, Ali, Inthakab Ali Mohamed, Beaumont, Karen, Elsaadany, Mohamed, Fernandes, Kay, Ally, Sameena Mohamed, Rangarajan, Harini, Sarathy, Varun, Selvanayagam, Sivarupan, Vedage, Dave, White, Matthew, Coton, Zoe, Joshy, Aricsa, Blunt, Mark, Curgenven, Hollie, Botfield, Liam, Dexter, Catherine, Kuravi, Aditya, Butler, Joanne, Chadwick, Robert, Ranga, Poonam, Richardson, Lisa, Virgilio, Emma, Anwer, Maddiha, Garg, Atul, Botfield, Donna, Marriott, Xana, Stewart, Keely, Mullan, Dee, Gaylard, Jane, Nowak, Justyna, Jones, Sian, Crawley, Rikki, Crew, Abigail, Cunningham, Mishell, Daniels, Allison, Harrison, Laura, Hope, Susan, Lancaster, Nicola, Matthews, Jamie, Wray, Gemma, Inweregbu, Ken, Cutts, Sarah, Miller, Katharine, Brady, Ailbhe, Chan, Rebekah, McIvor, Shane, Prady, Helena, Mathew, Bijoy, Little, Jeff, Furniss, Tim, Wright, Chris, King, Bernadette, Wasson, Christopher, O’Neill, Aisling, Turley, Christine, McGuigan, Peter, Collins, Erin, Finn, Stephanie, Green, Jackie, McAuley, Julie, Nair, Abitha, Quinn, Charlotte, Tauro, Suzanne, Ward, Kathryn, McGinlay, Michael, Reddy, Kiran, Ahmad, Norfaizan, Anderson, Samantha, Barker, Joann, Bauchmuller, Kris, Birchall, Kathryn, Bird, Sarah, Cawthron, Kay, Chetam, Luke, Cole, Joby, Donne, Ben, Foote, David, Ford, Amber, Hanratty, Helena, Harrington, Kate, Hesseldon, Lisa, Housley, Kay, Jackson, Yvonne, Jarman, Claire, Kibutu, Faith, Lenagh, Becky, Macharia, Irene, Masuko, Shamiso, Milner, Leanne, Newell, Helen, Nwafor, Lorenza, Oxspring, Simon, Phillips, Patrick, Raithatha, Ajay, Rowland-Jones, Sarah, Smith, Jacqui, Thompson, Roger, Trower, Helen, Walker, Sara, Watson, James, Wiles, Matthew, Lye, Alison, Willson, Jayne, Mills, Gary, Harris, Sansha, Hartill, Eleanor, Barron, Anthony, Collins, Ciara, Kaul, Sundeep, Nolan, Claire, Polgar, Oliver, Prendergast, Claire, Rogers, Paula, Shokkar, Rajvinder, Woodruff, Meriel, Mahay, Kanta, Reed, Anna, Meyrick, Hayley, Passmore, Heather, Farwell, James, O’Connell, Susan, Gregory, Jane, Barberis, Luigi, Harper, Rosemary, Smith, Tim, Armstrong, Diane, Bowey, Angie, Cowley, Anne, Corner, Andrew, Highgate, Judith, Rutherfurd, Claire, Taylor, Jo-Anne, Goodwin, Sarah, Eapen, Beena, Trim, Fiona, Donnison, Phil, Armstrong, Lisa, Bates, Hayley, Dooks, Emma, Farquhar, Fiona, Kitching, Amy, McParland, Chantal, Packham, Sophie, Hairsine, Brigid, Andreou, Premetie, Hales, Dawn, Mathews, Megha, Patel, Rekha, Barry, Peter, Flint, Neil, Hailstone, Jessica, Ghuman, Navneet, Leonard, Bethany, Lees, Rachel, Butcher, Deborah, Leng, Katy, Butterworth-Cowin, Nicola, O’Sullivan, Susie, Ghosh, Alison, Williams, Emma, Adams, Colene, Agasou, Anita, Arden, Tracie, Beekes, Mandy, Bowes, Amy, Boyle, Pauline, Button, Heather, Carnahan, Mandy, Carter, Anne, Childs, Danielle, Hurford, Fran, Hussain, Yasmin, Javaid, Ayesha, Jones, James, Leigh, Michael, Martin, Terry, Millward, Helen, Motherwell, Nichola, Newman, Julie, Rikunenko, Rachel, Stickley, Jo, Summers, Julie, Ting, Louise, Tivenan, Helen, Donaldson, Denise, Capps, Nigel, Cale, Emily, Jose, Sanal, Osbourne, Wendy, Pajak, Susie, Rankin, Jayne, Tonks, Louise, Baird, Tracy, Harkins, Margaret, Ruddy, Jim, West, Joe, Duffield, Joseph, Mallon, Lewis, Smith, Oliver, Smuts, Sara, Campbell, Andy, Davies, Cate, Davies, Sarah, Hughes, Rachel, Jobes, Lisa, Whitehead, Victoria, Watkins, Clare, Bowman, Fiona, Milligan, Barry, McPherson, Liane, Metherell, Stella, Harris, Nichola, Lake, Victoria, Radford, Elizabeth, Smallwood, Andy, Gopal, Shameer, Vassell, Katherine, Bell, Dina, Boyle, Rosalind, Douglas, Katie, Glass, Lynn, Lennon, Liz, Rattray, Austin, Lee, Emma, Jones, Danielle, Parsons, Penny, Attwood, Ben, Jefferson, Paul, Ranganathan, Mohan, Atwal, Inderjit, Campbell, Bridget, Day, Angela, Stagg, Camilla, Haynes, Emma, Ahmed, Cecilia, Clamp, Sarah, Colley, Julie, Haq, Risna, Hayes, Anne, Joseph, Sibet, Maqsood, Zahira, Hussain, Samia, Hulme, Jonathan, Domingos, Patience, Kumar, Rita, Purewal, Manjit, Taylor, Becky, Bunni, Lara, Latif, Monica, Jennings, Claire, Jose, Shilu, Marshall, Rebecca, Metryka, Aleksandra, Subramanian, Gayathri, Burgoyne, Adam, Tyler, Amanda, Waldron, Joanne, Hilltout, Paula, Evitts, Jayne, Ward, Geraldine, Bremmer, Pamela, Hawkins, Carl, Jackman, Sophie, Ogorek, Michal, Ashby, Kylie, Thornton, Lorraine, Mercer, Pauline, Halkes, Matthew, Revill, Adam, Saint, Bryony, Fletcher, Jo, Netherton, Kimberley, Chablani, Manish, Kirkby, Amy, Roper, Amanda, Szymiczek, Kinga, Sutherland, Isobel, O’Brien, Linda, Connell, Joanne, Davies, Kim, Lewis, Tracy, Omar, Zohra, Perkins, Emma, Sathe, Sonia, Davies, Ellie, Lyon, Alex, Mapfunde, Isheunesu, Willis, Charlotte, Hitchcock, Rachael, Hall, Kathryn, King, Christopher, Fagan, Andrew, Nazari, Roonak, Worsley, Lucy, Allibone, Suzanne, Kasipandian, Vidya, Patel, Amit, Cutting, Parisa, Genetu, Roman, Mac, Ainhi, Murphy, Anthony, Ward, Sinead, Butt, Fatima, Ayers, Amanda, Harrison, Wendy, Mackintosh, Katherine, North, Julie, Ashton, Lydia, Bi, Rehana, Owen, Samantha, Winmill, Helen, Scholefield, Barney, Blowing, Hannah, Williams, Erin, Duskova, Michaela, Edwards, Michelle, Rees, Alun, Thomas, Helen, Brooks, Jolene, Phipps, Janet, Brooks, Suzanne, Dennis, Catherine, Parris, Vicki, Srikaran, Sinduya, Sukha, Anisha, McGregor, Alistair, Tiongson, Gerlynn, Adams, Katie, Andrew, Benedict, Brayne, Adam, Carter, Sasha, Findlay, Louise, Fisher, Emma, Jackson, Peter, Kaye, Duncan, Parkin, Juliet, Tuckey, Victoria, Hunt, Jane, Love, Nicholas, van Koutrick, Lynne, Hanson, Ashley, Dent, Kathy, Horsley, Elizabeth, Pearson, Sandra, Spencer, Sue, Hutchinson, Dorothy, Potoczna, Dorota, Akhtar, Muhammad Nauman, Cottam, Lisa-Jayne, Sanders, Jack, Garcia, Sara Mingo, pakou, Glykeria, Filipe, Helder, Maharajh, Amitaa, de Neef, Mark, Martin, Daniel, Eastgate, Christine, Teoh, Poh Choo, Barrett, Fiona, Bradley, Clare, Donaldson, Avril, Mascarenhas, Mairi, O’Hara, Marianne, Okeefe, Laura, Clarke, Noreen, Whiteside, Jonathan, Campbell, Rachael, Matheson, Joanna, McDonald, Deborah, Patience, Donna, Rice, Polly, Clapham, Melanie, Mutch, Rachel, Craig, Hannah, Poultney, Una, Burns, Karen, Twiss, Sophie, Barton, Janet, George, Linsha, Harrop, Clare, Mathew, Sherly, Wright, David Justin, Harrison, Rachel, Toohie, Jordan, Chandler, Ben, Turnbull, Alison, Mallinson, Janine, Elliott, Kerry, Wolf-Roberts, Rebecca, Tench, Helen, Hobrok, Maria, Loosley, Ronda, McGuinness, Heather, Sims, Tanya, Afolabi, Deborah, Allison, Kathryn Sian, Anderson, Taya, Dore, Rachael, Jones, Dawn, Rogers, Naomi, Saunderson, Paula, Whitbread, Jennifer, O’Malley, Laura, Rad, Laura, Hawcutt, Daniel, Aldridge, Jonathan, Tolson, Melanie, Garrioch, Sweyn, Tomlinson, Joanne, Grosdenier, Michael, Loader, David, Kapoor, Ritoo, Hector, Gemma, Scherewode, Joslan, Sri-Chandana, Chunda, Stephenson, Lorraine, Marsh, Sarah, Rosa, Arnold Dela, Jhanji, Shaman, Bemand, Thomas, Howle, Ryan, Baikady, Ravishankar Rao, Thomas, Benjamin, Black, Ethel, Tatham, Kate, Gurram, Sambasivarao, Watson, Ekaterina, Quaid, Sheena, Saunderson, Anne, O’Brien, Rachel, Moultrie, Sam, Service, Jen, Cheyne, Clare, Odam, Miranda, Wiliams, Alison, Barnes, Nicky, Csabi, Peter, Rocha, Joana Da, Glynou, Louika, Huffenberger, Amy, Bryant, Jade, Pickard, Amy, Roe, Nicholas, Bellini, Arianna, Mayer, Anton, Burrow, Amy, Colley, Natalie, Evans, Jayne, Howlett, Alex, Khalifeh, Zeinab, Pryce, Jerldine, Gorman, Claire, Brady, Rebecca, Timlick, Elizabeth, Antoine, Pierre, Gupta, Abhinhav, Hardy, John, Houlden, Henry, Moncur, Eleanor, Tucci, Arianna, Tariq, Ambreen, Tagliavini, Emma, Ramsay, Becky, Fidler, Katy, Donnelly, Kevin, Hollis, Rebecca, Barr, Jocelyn, Boyd, Elizabeth, Irvine, Val, Shelley, Ben, Buckley, Julie, Hamilton, Charlene, Valdeavella, Kathryn, Bircham, Sarah, Liggett, Steven, Patil, Anand, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Fowler, Tom A., Elliott, Paul, Tenesa, Albert, Aitkin, Emma, Aravindan, Latha, Armstrong, Ruth, Biggs, Heather, Boz, Ceilia, Brown, Adam, Chikowore, Primmy, Coutts, Audrey, Coyle, Judy, Cullum, Louise, Das, Sukamal, Day, Nicky, Donnelly, Lorna, Duncan, Esther, Finernan, Paul, Fourman, Max Head, Furlong, Anita, Furniss, James, Gallagher, Bernadette, Gilchrist, Tammy, Golightly, Ailsa, Hafezi, Katarzyna, Hamilton, Debbie, Hendry, Ross, Kearns, Naomi, Law, Dawn, Law, Rachel, Law, Sarah, Lidstone-Scott, Rebecca, Lauder, Christen, Macgillivray, Louise, Maclean, Alan, Mal, Hanning, McCafferty, Sarah, Mcmaster, Ellie, Meikle, Jen, Moore, Shona C., Murphy, Sheena, Mybaya, Hellen, Oosthuyzen, Wilna, Zheng, Chenqing, Chen, Jiantao, Paterson, Trevor, Tucker, Petra, Schon, Katherine, Stenhouse, Andrew, Das, Mihaela, Swets, Maaike, Szoor-McElhinney, Helen, Taneski, Filip, Turtle, Lance, Wackett, Tony, Ward, Mairi, Weaver, Jane, Wrobel, Nicola, Rakitko, Alexander, Ilinsky, Valery, Yermakovich, Danat, Popov, Iaroslav, Chernitsov, Alexander, Kovalenko, Elena, Vergasova, Ekaterina, Prokhorov, Alexandr, Krasnenko, Anna, Plotnikov, Nikolay, Stetsenko, Ivan, Kim, Anna, Cirulli, Elizabeth T., Schiabor Barrett, Kelly M., Bolze, Alexandre, White, Simon, Washington, Nicole L., Lu, James T., Riffle, Stephen, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Leonetti, Nicole, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Grzymski, Joseph J., Joshi, Madhvi N., Dixit, Raghav D., Shah, Pranay K., Upadhyay, Kamlesh J., Chuhan, Naresh T., Desai, Kairavi J., Shah, Meenakshi R., Modi, Bhavesh, Joshi, Chaitanya G., Pandit, Ramesh J., Singh, Indra, Ansari, Afzal I., Raval, Janvi N., Patel, Zarna Z., Moreno-Estrada, Andres, Vázquez-Pérez, Joel Armando, Castillejos-López, Manuel, Aquino-Gálvez, Arnoldo, Shamah-Levy, Teresa, Ávila-Arcos, María C., Luna, María Teresa Tusié, Hidalgo-Miranda, Alfredo, Barberena-Jonas, Carmina, Quinto-Cortés, Consuelo D., Ávila-Arcos, Marco Antonio, Huerta-Chagoya, Alicia, García-García, Lourdes, Barnetche, Jesús Martinez, Alpuche-Aranda, Celia, Rivera, Juan A., Gutiérrez, Tonatiuh Barrientos, Ochoa-Guzmán, Ana, Ordoñez-Sánchez, Maria Luisa, Segura-Kato, Yayoi, Herrera-Montalvo, Luis Alonso, Mendoza-Vargas, Alfredo, Reyes-Grajeda, Juan Pablo, Cruz-Cruz, Alonso D., Velázquez-Cruz, Rafael, Torres-Espíndola, Luz María, Sierra-Vargas, Martha Patricia, Camarena, Angel, Ruiz, Víctor, Chávez-Alderete, Jaime, Jaime-Capetillo, María Esther, Guadarrama-Pérez, Cristóbal, Zúñiga-Ramos, Joaquin, Olivera-Ramírez, Alejandra, Martínez, Miguel Angel López, Serna-Muñoz, Ricardo, Garmendia, Adriana, Namkoong, Ho, Okada, Yukinori, Imoto, Seiya, Katayama, Kazuhiko, Fukunaga, Koichi, Kitagawa, Yuko, Sato, Toshiro, Hasegawa, Naoki, Kumanogoh, Atsushi, Kimura, Akinori, Ai, Masumi, Tokunaga, Katsushi, Kanai, Takanori, Miyano, Satoru, Ogawa, Seishi, Edahiro, Ryuya, Sonehara, Kyuto, Shirai, Yuya, Ishii, Makoto, Kabata, Hiroki, Masaki, Katsunori, Kamata, Hirofumi, Ikemura, Shinnosuke, Chubachi, Shotaro, Okamori, Satoshi, Terai, Hideki, Tanaka, Hiromu, Morita, Atsuho, Lee, Ho, Asakura, Takanori, Sasaki, Junichi, Morisaki, Hiroshi, Uwamino, Yoshifumi, Nanki, Kosaku, Mikami, Yohei, Tomono, Kazunori, Kato, Kazuto, Matsuda, Fumihiko, Takahashi, Meiko, Hizawa, Nobuyuki, Takeda, Yoshito, Hirata, Haruhiko, Shiroyama, Takayuki, Miyawaki, Satoru, Suzuki, Ken, Maeda, Yuichi, Nii, Takuro, Noda, Yoshimi, Niitsu, Takayuki, Adachi, Yuichi, Enomoto, Takatoshi, Amiya, Saori, Hara, Reina, Takahashi, Kunihiko, Anzai, Tatsuhiko, Hasegawa, Takanori, Ito, Satoshi, Koike, Ryuji, Endo, Akifumi, Uchimura, Yuji, Miyazaki, Yasunari, Honda, Takayuki, Tateishi, Tomoya, Tohda, Shuji, Ichimura, Naoya, Sonobe, Kazunari, Sassa, Chihiro, Nakajima, Jun, Nannya, Yasuhito, Omae, Yosuke, Takahashi, Kazuhisa, Harada, Norihiro, Hiki, Makoto, Takagi, Haruhi, Nakamura, Ai, Tagaya, Etsuko, Kawana, Masatoshi, Arimura, Ken, Ishiguro, Takashi, Takayanagi, Noboru, Isono, Taisuke, Takaku, Yotaro, Takano, Kenji, Anan, Ryusuke, Nakajima, Yukiko, Nakano, Yasushi, Nishio, Kazumi, Ueda, Soichiro, Hayashi, Reina, Tateno, Hiroki, Hase, Isano, Yoshida, Shuichi, Suzuki, Shoji, Mitamura, Keiko, Saito, Fumitake, Ueda, Tetsuya, Azuma, Masanori, Nagasaki, Tadao, Yasui, Yoshinori, Hasegawa, Yoshinori, Mutoh, Yoshikazu, Yoshiyama, Takashi, Shoko, Tomohisa, Kojima, Mitsuaki, Adachi, Tomohiro, Ishikawa, Motonao, Takahashi, Kenichiro, Watanabe, Kazuyoshi, Manabe, Tadashi, Ito, Fumimaro, Fukui, Takahiro, Funatsu, Yohei, Koh, Hidefumi, Hirai, Yoshihiro, Kawashima, Hidetoshi, Narita, Atsuya, Niwa, Kazuki, Sekikawa, Yoshiyuki, Saito, Fukuki, Yoshiya, Kazuhisa, Yoshihara, Tomoyuki, Suzuki, Yusuke, Nakayama, Sohei, Masuzawa, Keita, Nishi, Koichi, Nishitsuji, Masaru, Tani, Maiko, Inoue, Takashi, Hirano, Toshiyuki, Kobayashi, Keigo, Miyazawa, Naoki, Kimura, Yasuhiro, Sado, Reiko, Ogura, Takashi, Kitamura, Hideya, Murohashi, Kota, Nakachi, Ichiro, Baba, Rie, Arai, Daisuke, Fuke, Satoshi, Saito, Hiroshi, Kuwahara, Naota, Fujiwara, Akiko, Okada, Takenori, Baba, Tomoya, Noda, Junya, Mashimo, Shuko, Yagi, Kazuma, Shiomi, Tetsuya, Hashiguchi, Mizuha, Odani, Toshio, Mochimaru, Takao, Oyamada, Yoshitaka, Mori, Nobuaki, Izumi, Namiki, Nagata, Kaoru, Taki, Reiko, Murakami, Koji, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hayashi, Kentaro, Shimizu, Tetsuo, Gon, Yasuhiro, Fujitani, Shigeki, Tsuchida, Tomoya, Yoshida, Toru, Kagaya, Takashi, Kita, Toshiyuki, Sakagami, Satoru, Kimizuka, Yoshifumi, Kawana, Akihiko, Nakamura, Yoshihiko, Ishikura, Hiroyasu, Takata, Tohru, Kikuchi, Takahide, Taniyama, Daisuke, Nakamura, Morio, Kodama, Nobuhiro, Kaneyama, Yasunari, Maeda, Shunsuke, Nagasaki, Yoji, Okamoto, Masaki, Ishihara, Sayoko, Ito, Akihiro, Chihara, Yusuke, Takeuchi, Mayumi, Onoi, Keisuke, Hashimoto, Naozumi, Wakahara, Keiko, Ando, Akira, Masuda, Makoto, Wakabayashi, Aya, Watanabe, Hiroki, Sageshima, Hisako, Nakada, Taka-Aki, Abe, Ryuzo, Shimada, Tadanaga, Kawamura, Kodai, Ichikado, Kazuya, Nishiyama, Kenta, Yamasaki, Masaki, Hashimoto, Satoru, Kusaka, Yu, Ohba, Takehiko, Isogai, Susumu, Takada, Minoru, Kanda, Hidenori, Komase, Yuko, Sano, Fumiaki, Asano, Koichiro, Oguma, Tsuyoshi, Harada, Masahiro, Takahashi, Takeshi, Shibusawa, Takayuki, Abe, Shinji, Kono, Yuta, Togashi, Yuki, Izumo, Takehiro, Inomata, Minoru, Awano, Nobuyasu, Ogawa, Shinichi, Ogata, Tomouki, Ishihara, Shoichiro, Kanehiro, Arihiko, Ozaki, Shinji, Fuchimoto, Yasuko, Kitagawa, Yuichiro, Yoshida, Shozo, Ogura, Shinji, Nishiyama, Kei, Yoshida, Kousuke, Beppu, Satoru, Fukuyama, Satoru, Eriguchi, Yoshihiro, Yonekawa, Akiko, Inoue, Yoshiaki, Yamagata, Kunihiro, Chiba, Shigeru, Narumoto, Osamu, Nagai, Hideaki, Ooshima, Nobuharu, Motegi, Mitsuru, Sagara, Hironori, Tanaka, Akihiko, Ohta, Shin, Shibata, Yoko, Tanino, Yoshinori, Sato, Yuki, Yamada, Yuichiro, Hashino, Takuya, Shinoki, Masato, Iwagoe, Hajime, Imamura, Tomonori, Umeda, Akira, Shimada, Hisato, Endo, Mayu, Hayashi, Shinichi, Takahashi, Mai, Nakano, Shigefumi, Yatomi, Masakiyo, Maeno, Toshitaka, Ishii, Tomoo, Utsugi, Mitsuyoshi, Ono, Akihiro, Kanaoka, Kensuke, Ihara, Shoichi, Komuta, Kiyoshi, Nishida, Nao, Kawai, Yosuke, Sugiyama, Masaya, Alawneh, Laith M., Maswadeh, Kinda B., Alsoub, Fatima S., AlRawashdeh, Tala J., Esawi, Ezaldeen, Abu Alragheb, Bayan O., Maswadeh, Ahmad B., Al-Kadash, Abdulfattah, Al-Ani, Abdallah, Alsafadi, Dana B., Shahin, Mohammad A., Qtaish, Nuseibah Al, Alawneh, Fade M., Abulail, Joseph A., Zhlawi, Hadi J., Alhousani, Tasneem N., Alzuraiqi, Mohammad R., Al-Ja’afreh, Mohammad M., Allouzy, Sara K., ALjalamdeh, Mothafer, Mansour, Tareq M., Alamer, Lina M., Issa, Ali Banni, Bani younis, Fatima M., Hawari, Feras I., Hayajneh, Wail A., Obeidat, Nathir M., Ahram, Mamoun, Zhlawi, Moh’d Wahib J., Alshaer, Walhan, Al-Kasasbeh, Malak M., Naffa, Randa G., Ismail, Mohammad A., Abdullah, Mohammed S., Ismail, Said I., Obeidat, Ma’en, Hernández Cordero, Ana I., Sin, Don D., Bossé, Yohan, Joubert, Philippe, Hao, Ke, Nickle, David, Timens, Wim, van den Berge, Maarten, Feng, Yen-Chen Anne, Mercader, Josep, Weiss, Scott T., Karlson, Elizabeth W., Smoller, Jordan W., Murphy, Shawn N., Meigs, James B., Woolley, Ann E., Green, Robert C., Mandla, Ravi, Schroeder, Philip, Perez, Emma F., Lee, Seung Hyuk T., Flores-Silva, Fernando Daniel, Chiquete, Erwin, Cantú-Brito, Carlos, Sifuentes-Osornio, José, de León-Garduño, Alfredo Ponce, Román-Montes, Carla Marina, Chávez-Manzanera, Emma, Velasco, Donaji Gómez, Martagón-Rosado, Alexandro, Cruz-Bautista, Ivette, Gómez-Pérez, Francisco Javier, Díaz-Olavarrieta, Claudia, Valdés, Paloma Almeda, Muñóz-Hernández, Linda Liliana, Mehta, Roopa Pravin, Elías-López, Daniel, Tusié-Luna, Teresa, Pajukanta, Päivi, Sukhatme, Mihir G., Moreno-Macías, Hortensia, Ruth, Johnson, González-Behn-Eschenburg, Sebastián, García-Grimshaw, Miguel, Guillen-Pineda, Luz Elizabeth, de los Ángeles Vargas-Martínez, María, Rodríguez, Maribel, Rodríguez-Guillén, Rosario, Ordoñez, María Luisa, Rajme-López, Sandra, González-Lara, María Fernanda, Luna-Moreno, Dalia, de Jesús Suárez López, Jannet, Guillén-Quintero, Daniela Mariel, Vega, Juan, Duran-Coyote, Salvador, Guerra-García, María Teresa, Durán-Gómez, Michelle, Vigueras-Hernández, Alma, Ramírez-Jiménez, Marco Eduardo, Grajeda-González, Samara Lissete, Ramos-Galicia, Enrique Manuel, Ramírez-Carrillo, Martha Fernanda, Fernandez-Ruiz, Juan, Chirino-Pérez, Amanda, Romero-Molina, Ángel Omar, Zavaleta, David Alejandro Fuentes, Jaramillo, María Andrea Mac Donald, López, Katia Jarely Prieto, Incontri-Abraham, Diego, Rosado, Wendy Natalia, Catalán, María Alonso, Aguilar, Sonia Evelyn Vital, Zamudio, Ileana Paola Montero, Ruíz-Ruíz, Eduardo, de Jesús Carrera García, Kevin, Guerrero, Cristina Villarreal, Martínez, Ana Isabel Rodríguez, Moscoso-Sánchez, Rogelio, del Consuelo Rodríguez Mancilla, María, Villa, Antonio, Luna-Ramírez, Samuel Alejandro, Hernández-Hernández, Sergio, Frias, Erika, Campos, Alejandro, Morales-Sosa, Paola Alessandra, Toxqui-Merchant, Luis Enrique, García, Karla, Pasaniuc, Bogdan, Butte, Manish J., Geschwind, Daniel H., Aguilar-Salinas, Carlos A., Heidecker, Bettina, Kurth, Florian, Sander, Leif E., Skurk, Carsten, Landmesser, Ulf, Karadeniz, Zehra, Wang, Xiaomin, Poller, Wolfgang, Suwalski, Phillip, Ripke, Stephan, Braun, Alice, Kraft, Julia, Mayer, Alena, Lippert, Lena J., Helbig, Elisa T., Thibeault, Charlotte, Awasthi, Swapnil, Mbarek, Hamdi, Saad, Chadi, Al-Sarraj, Yaser, Badji, Radja Messai, Al-Muftah, Wadha, Thani, Asma Al, Afifi, Nahla, Sadiq, Fouzia, Khan, Mohammad I., Bhutta, Muhammad J., Khan, Hania, Khan, Madeeha, Ain, Quratul, Junaid, Ayesha, Khan, Ejaz A., Sypniewski, Mateusz, Lejman, Adrian, Zawadzki, Paweł, Sztromwasser, Paweł, Król, Zbigniew, Dobosz, Paula, Stojak, Joanna, Flores, Carlos, Carracedo, Ángel, Aguilar, Carlos, Arranz, María J., Baptista-Rosas, Raúl C., Bezerra, Joao F., Bezerra, Marcos A. C., Brugada, Ramón, Bustos, Matilde, Castano, Luis, Conde-Vicente, Rosa, Cordero-Lorenzana, M. Lourdes, De Martino-Rodríguez, Alba, Domínguez-Garrido, Elena, Fariñas, María Carmen, Gil-Fournier, Belén, Herrero, María José, Lattig, María Claudia, Martín-López, Caridad, Martín, Vicente, Martinez-Nieto, Oscar, Martinez-Lopez, Iciar, Mazzeu, Juliana F., Macías, Eleuterio Merayo, Cuerda, Victor Moreno, Silbiger, Vivian N., Oliveira, Silviene F., Parellada, Mara, Santos, Ney P. C., Pérez-Matute, Patricia, Perez, Patricia, Perucho, Teresa, Porras-Hurtado, Gloria L., Pujol, Aurora, Fernández-Rodríguez, Amanda, Jimenez-Sousa, María A., Rodríguez-Ruiz, Emilio, Rodriguez-Artalejo, Fernando, Rodriguez-Garcia, José A., Ruiz-Cabello, Francisco, Soria, José Manuel, Tamayo, Eduardo, Teper, Alejandro, Torres-Tobar, Lilian, Urioste, Miguel, Yáñez, Zuleima, Zarate, Ruth, Guillen-Navarro, Encarna, Ayuso, Carmen, González-Neira, Anna, Riancho, José A., Rojas-Martinez, Augusto, Lapunzina, Pablo, Cruz, Raquel, Diz-de Almeida, Silvia, Ceballos, Francisco C., Lorenzo-Salazar, José M., González-Montelongo, Rafaela, Quintela, Inés, Pita, Guillermo, Gago-Domínguez, Manuela, Porras, Marta Sevilla, Tenorio-Castaño, Jair Antonio, Nevado, Julian, Aguado, Jose María, Aguilera-Albesa, Sergio, Almadana, Virginia, Almoguera, Berta, Alvarez, Nuria, Andreu-Bernabeu, Álvaro, Arango, Celso, Artiga, Maria-Jesus, Barreda-Sánchez, María, Belhassen-Garcia, Moncef, Boix-Palop, Lucía, Brion, María, Carbonell, Cristina, Castelao, Jose E., Cortes-Sanchez, Jose L., Corton, Marta, Darnaude, M. Teresa, del Campo-Pérez, Victor, de Bustamante, Aranzazu Diaz, Luchessi, Andre D., Eiros, Rocío, Sanabria, Gladys Mercedes Estigarribia, Fernández-Robelo, Uxía, Fernández-Villa, Tania, Gómez-Arrue, Javier, Álvarez, Beatriz González, de Quirós, Fernan Gonzalez Bernaldo, González-Peñas, Javier, Gutiérrez-Bautista, Juan F., Herrero-Gonzalez, Antonio, Borja, Anabel Liger, Lopez-Rodriguez, Rosario, Mancebo, Esther, Martinez-Resendez, Michel F., Martinez-Perez, Angel, Minguez, Pablo, Ortega-Paino, Eva, Paz-Artal, Estela, Pérez-Tomás, M. Elena, Pinsach-Abuin, Mel·lina, Pompa-Mera, Ericka N., León, Soraya Ramiro, Resino, Salvador, Fernandes, Marianne R., Ruiz-Hornillos, Javier, Ryan, Pablo, Souto, Juan Carlos, Tamayo-Velasco, Alvaro, Taracido-Fernandez, Juan Carlos, Valencia-Ramos, Juan, de Heredia, Miguel López, Pedersen, Ole B., Erikstrup, Christian, Ostrowski, Sisse R., Stefansson, Kari, Mikkelsen, Susan, Sørensen, Erik, Burgos, Celia, Andersen, Steffen, Brugdorf, Kristoffer, Hansen, Thomas F., Hjalgrim, Henrik, Jemec, Gregor B., Nyegaard, Mette, Werge, Thomas, Johansson, Pär I., Didriksen, Maria, Schwinn, Michael, Jacobsen, Rikke L., Hindhede, Lotte, Rostgaard, Klaus, Gudbjartsson, Daniel, Stefánsson, Hreinn, Þorsteinsdóttir, Unnur, Nielsen, Kaspar R., Bruun, Mie Topholm, Dinh, Khoa M., Larsen, Margit A. H., Sækmose, Susanne G., Zeberg, Hugo, Nkambul, Lindo, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklos, Tardif, Nicolas, Rooyackers, Olav, Grip, Jonathan, Maricic, Tomislav, Heid, Iris M., Wagner, Ralf, Überla, Klaus, Winkler, Thomas W., Wiegrebe, Simon, Gorski, Mathias, Stark, Klaus J., Peterhoff, David, Einhauser, Sebastian, Niller, Hans-Helmut, Beileke, Stephanie, Johnson, Ruth, Freimer, Nelson, Ding, Yi, Chiu, Alec, Chang, Timothy S., Boutros, Paul, Karczewski, Konrad J., Martin, Alicia R., Wilson, Daniel J., Spencer, Chris C. A., Crook, Derrick W., Wyllie, David H., O’Connell, Anne Marie, Atkinson, Elizabeth G., Tsuo, Kristin, Baya, Nikolas, Turley, Patrick, Gupta, Rahul, Walters, Raymond K., Palmer, Duncan S., Sarma, Gopal, Solomonson, Matthew, Cheng, Nathan, Lu, Wenhan, Churchhouse, Claire, Goldstein, Jacqueline I., King, Daniel, Zhou, Wei, Seed, Cotton, Daly, Mark J., Finucane, Hilary, Bryant, Sam, Satterstrom, F. Kyle, Band, Gavin, Earle, Sarah G., Lin, Shang-Kuan, Arning, Nicolas, Koelling, Nils, Armstrong, Jacob, Rudkin, Justine K., Callier, Shawneequa, Cusick, Caroline, Fernandez-Cadenas, Israel, Planas, Anna M., Perez-Tur, Jordi, Llucià-Carol, Laia, Cullell, Natalia, Muiño, Elena, Cárcel-Márquez, Jara, DeDiego, Marta L., Iglesias, Lara Lloret, Soriano, Alex, Rico, Veronica, Agüero, Daiana, Bedini, Josep L., Lozano, Francisco, Domingo, Carlos, Robles, Veronica, Ruiz-Jaén, Francisca, Márquez, Leonardo, Gomez, Juan, Coto, Eliecer, Albaiceta, Guillermo M., García-Clemente, Marta, Dalmau, David, Arranz, Maria J., Dietl, Beatriz, Serra-Llovich, Alex, Soler-Palacin, Pere, Colobran, Roger, Martin-Nalda, Andrea, Parra-Martínez, Alba, Bernardo, David, Rojo, Silvia, Fiz-López, Aida, Arribas-Rodriguez, Elisa, Cal-Sabater, Paloma, Segura, Tomás, González-Villar, Esther, Serrano-Heras, Gemma, Martí-Fàbregas, Joan, Jiménez-Xarrié, Elena, de Felipe Mimbrera, Alicia, Masjuan, Jaime, García-Madrona, Sebastian, Domínguez-Mayoral, Anna, Villalonga, Joan Montaner, Menéndez-Valladares, Paloma, Kanai, M, Andrews, S, Cordioli, M, Stevens, C, Neale, B, Daly, M, Ganna, A, Pathak, G, Iwasaki, A, Karjalainen, J, Mehtonen, J, Pirinen, M, Chwialkowska, K, Trankiem, A, Balaconis, M, Veerapen, K, Wolford, B, Ahmad, H, von Hohenstaufen Puoti, K, Boer, C, Boua, P, Butler-Laporte, G, Cadilla, C, Chwiałkowska, K, Colombo, F, Douillard, V, Dueker, N, Dutta, A, El-Sherbiny, Y, Eltoukhy, M, Esmaeeli, S, Faucon, A, Fave, M, Cadenas, I, Francescatto, M, Francioli, L, Franke, L, Fuentes, M, Durán, R, Cabrero, D, Harry, E, Jansen, P, Szentpéteri, J, Kaja, E, Kirk, C, Kousathanas, A, Krieger, J, Patel, S, Lemaçon, A, Limou, S, Lió, P, Marouli, E, Marttila, M, Medina-Gómez, C, Michaeli, Y, Migeotte, I, Mondal, S, Moreno-Estrada, A, Moya, L, Nakanishi, T, Nasir, J, Pasko, D, Pearson, N, Pereira, A, Priest, J, Prijatelj, V, Prokić, I, Teumer, A, Várnai, R, Romero-Gómez, M, Roos, C, Rosenfeld, J, Ruolin, L, Schulte, E, Schurmann, C, Sedaghati-khayat, B, Shaheen, D, Shivanathan, I, Sipeky, C, Sirui, Z, Striano, P, Tanigawa, Y, Remesal, A, Vadgama, N, Vallerga, C, van der Laan, S, Verdugo, R, Wang, Q, Wei, Z, Zainulabid, U, Zárate, R, Auton, A, Shelton, J, Shastri, A, Weldon, C, Filshtein-Sonmez, T, Coker, D, Symons, A, Aslibekyan, S, O’Connell, J, Ye, C, Hatoum, A, Agrawal, A, Bogdan, R, Colbert, S, Thompson, W, Fan, C, Johnson, E, Niazyan, L, Davidyants, M, Arakelyan, A, Avetyan, D, Bekbossynova, M, Tauekelova, A, Tuleutayev, M, Sailybayeva, A, Ramankulov, Y, Zholdybayeva, E, Dzharmukhanov, J, Kassymbek, K, Tsechoeva, T, Turebayeva, G, Smagulova, Z, Muratov, T, Khamitov, S, Kwong, A, Timpson, N, Niemi, M, Rahmouni, S, Guntz, J, Beguin, Y, Pigazzini, S, Nkambule, L, Georges, M, Moutschen, M, Misset, B, Darcis, G, Gofflot, S, Bouysran, Y, Busson, A, Peyrassol, X, Wilkin, F, Pichon, B, Smits, G, Vandernoot, I, Goffard, J, Tiembe, N, Morrison, D, Afilalo, J, Mooser, V, Richards, J, Rousseau, S, Durand, M, Forgetta, V, Laurent, L, Afrasiabi, Z, Bouab, M, Tselios, C, Xue, X, Afilalo, M, Oliveira, M, St-Cyr, J, Boisclair, A, Ragoussis, J, Auld, D, Kaufmann, D, Lathrop, G, Bourque, G, Décary, S, Falcone, E, Montpetit, A, Piché, A, Renoux, C, Tremblay, K, Tse, S, Zawati, M, Davis, L, Cox, N, Below, J, Sealock, J, Shuey, M, Polikowsky, H, Petty, L, Shaw, D, Chen, H, Zhu, W, Schmidt, A, Ludwig, K, Maj, C, Rolker, S, Balla, D, Behzad, P, Nöthen, M, Fazaal, J, Keitel, V, Jensen, B, Feldt, T, Marx, N, Dreher, M, Pink, I, Cornberg, M, Illig, T, Lehmann, C, Schommers, P, Rybniker, J, Augustin, M, Knopp, L, Kurth, I, Eggermann, T, Volland, S, Berger, M, Brenner, T, Hinney, A, Witzke, O, Konik, M, Bals, R, Herr, C, Ludwig, N, Walter, J, Latz, E, Schmidt, S, Brooks, J, Bull, S, Elliott, L, Gagnon, F, Greenwood, C, Hung, R, Lawless, J, Paterson, A, Sun, L, Rauh, M, Briollais, L, Gingras, A, Bombard, Y, Pugh, T, Simpson, J, Goneau, L, Halevy, A, Maslove, D, Borgundvaag, B, Devine, L, 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C., Thompson, Wesley K., Fan, Chun Chieh, Johnson, Emma C., Niazyan, Lyudmila, Davidyants, Mher, Arakelyan, Arsen, Avetyan, Diana, Bekbossynova, Makhabbat, Tauekelova, Ainur, Tuleutayev, Mukhtar, Sailybayeva, Aliya, Ramankulov, Yerlan, Zholdybayeva, Elena, Dzharmukhanov, Jarkyn, Kassymbek, Kuat, Tsechoeva, Tatyana, Turebayeva, Gulsimzhan, Smagulova, Zauresh, Muratov, Timur, Khamitov, Sadyk, Kwong, Alex S. F., Timpson, Nicholas J., Niemi, Mari E. K., Rahmouni, Souad, Guntz, Julien, Beguin, Yves, Pigazzini, Sara, Nkambule, Lindokuhle, Georges, Michel, Moutschen, Michel, Misset, Benoit, Darcis, Gilles, Gofflot, Stéphanie, Bouysran, Youssef, Busson, Adeline, Peyrassol, Xavier, Wilkin, Françoise, Pichon, Bruno, Smits, Guillaume, Vandernoot, Isabelle, Goffard, Jean-Christophe, Tiembe, Nicky, Morrison, David R., Afilalo, Jonathan, Mooser, Vincent, Richards, J. 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Mark, Bourque, Guillaume, Décary, Simon, Falcone, Emilia Liana, Montpetit, Alexandre, Piché, Alain, Renoux, Christel, Tremblay, Karine, Tse, Sze Man, Zawati, Ma’n H., Davis, Lea K., Cox, Nancy J., Below, Jennifer E., Sealock, Julia M., Faucon, Annika B., Shuey, Megan M., Polikowsky, Hannah G., Petty, Lauren E., Shaw, Douglas M., Chen, Hung-Hsin, Zhu, Wanying, Schmidt, Axel, Ludwig, Kerstin U., Maj, Carlo, Rolker, Selina, Balla, Daniella, Behzad, Pari, Nöthen, Markus M., Fazaal, Julia, Keitel, Verena, Jensen, Björn-Erik Ole, Feldt, Torsten, Marx, Nikolaus, Dreher, Michael, Pink, Isabell, Cornberg, Markus, Illig, Thomas, Lehmann, Clara, Schommers, Philipp, Rybniker, Jan, Augustin, Max, Knopp, Lisa, Kurth, Ingo, Eggermann, Thomas, Volland, Sonja, Berger, Marc M., Brenner, Thorsten, Hinney, Anke, Witzke, Oliver, Konik, Margarethe J., Bals, Robert, Herr, Christian, Ludwig, Nicole, Walter, Jörn, Latz, Eicke, Schmidt, Susanne V., Brooks, Jennifer D., Bull, Shelley, Elliott, Lloyd T., Gagnon, France, Greenwood, Celia M. T., Hung, Rayjean J., Lawless, Jerry F., Paterson, Andrew D., Sun, Lei, Rauh, Michael, Briollais, Laurent, Gingras, Anne-Claude, Bombard, Yvonne, Pugh, Trevor J., Simpson, Jared, Goneau, Lee W., Halevy, Anat R., Maslove, David M., Borgundvaag, Bjug, Devine, Luke, Bearss, Erin, Richardson, David, Arnoldo, Saranya, Friedman, Steven Marc, Taher, Ahmed, Stern, Seth, Dagher, Marc, Vasilevska-Ristovska, Jovanka, Biggs, Catherine M., Mickiewicz, Beata, Strug, Lisa J., Scherer, Stephen W., Aziz, Naveed, Jones, Steven J. M., Knoppers, Bartha M., Lathrop, Mark, Turvey, Stuart E., Yeung, Rae S. M., Allen, Upton, Cheung, Angela M., Herridge, Margaret S., Hunt, Miranda, Lerner-Ellis, Jordan, Taher, Jennifer, Parekh, Rulan S., Hiraki, Linda T., Cowan, Juthaporn, Ducharme, Francine M., Ostrowski, Mario, Bernier, Francois P., Kellner, Jim, Garg, Elika, Yoo, Samantha, Vlasschaert, Caitlyn, Frangione, Erika, Chung, Monica, Noor, Abdul, Greenfeld, Elena, Colwill, Karen, Clausen, Marc, Chao, Gary, Yue, FengYun, Fritzler, Marvin, Whitney, Joseph, Thiruvahindrapuram, Bhooma, Garant, Jean-Michel, Abraham, Rohan, Davis, Adrienne, Campigotto, Aaron, Papenburg, Jesse, Niranjan, Kissoon, Betschel, Stephen, Sadarangani, Manish, Barton-Forbes, Michelle, Hanley, Michaela, Fung, Chun Yiu Jordan, Lapadula, Elisa, MacDonald, Georgia, Puopolo, Michael, Kaushik, Deepanjali, Nirmalanathan, Konika, Wong, Iris, Khan, Zeeshan, Zarei, Natasha, Michalowska, Maria, Modi, Bhavi P., Persia, Pourshahnazari, Estacio, Antonio, Buchholz, Megan, Cheatley, Patti Lou, Lorenti, Miranda, Aman, Nowrin F., Matveev, 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Tsourlos, Stavros, Athanasiou, Lazaros, Kolios, Nikolaos-Gavriil, Pappa, Christiana, Papathanasiou, Alexandros, Pargana, Eleni, Nasiou, Maria, Kosmidou, Maria, Rapti, Iro, Ntotsikas, Evangelos, Chaliasos, Konstantinos, Ntzani, Evangelia, Evangelou, Evangelos, Gartzonika, Konstantina, Georgiou, Ioannis, Tzoulaki, Ioanna, Ellinghaus, David, Degenhardt, Frauke, Cáceres, Mario, Juzenas, Simonas, Lenz, Tobias L., Albillos, Agustín, Julià, Antonio, Prati, Daniele, Solligård, Erik, Garcia, Federico, Tran, Florian, Hanses, Frank, Baselli, Guido, Zoller, Heinz, Holter, Jan Cato, Fernández, Javier, Barretina, Jordi, Valenti, Luca, Bujanda, Luis, Buti, Maria, D’Amato, Mauro, Banales, Jesus M., Rosenstiel, Philip, Koehler, Philipp, Invernizzi, Pietro, de Cid, Rafael, Asselta, Rosanna, Schreiber, Stefan, Duga, Stefano, Hehr, Ute, Franke, Andre, Maya-Miles, Douglas, Hov, Johannes R., Karlsen, Tom H., Folseraas, Trine, Teles, Ana, Tanck, Anja, Gassner, Christoph, Azuure, Clinton, Wacker, Eike Matthias, Uellendahl-Werth, Florian, Hemmrich-Stanisak, Georg, ElAbd, Hesham, Kässens, Jan, Arora, Jatin, Lerga-Jaso, Jon, Wienbrandt, Lars, Rühlemann, Malte Christoph, Wendorff, Mareike, Figuera Basso, Maria E., Vadla, May Sissel, Wittig, Michael, Braun, Nicole, Lenning, Ole Bernt, Özer, Onur, Myhre, Ronny, Raychaudhuri, Soumya, Wesse, Tanja, Albrecht, Wolfgang, Yi, Xiaoli, Ortiz, Aaron Blandino, de Salazar, Adolfo, Chercoles, Adolfo Garrido, Palom, Adriana, Ruiz, Agustín, Garcia-Fernandez, Alba-Estela, Blanco-Grau, Albert, Mantovani, Alberto, Holten, Aleksander Rygh, Bandera, Alessandra, Cherubini, Alessandro, Protti, Alessandro, Aghemo, Alessio, Gerussi, Alessio, Ramirez, Alfredo, Nebel, Almut, Barreira, Ana, Lleo, Ana, Kildal, Anders Benjamin, Biondi, Andrea, Caballero-Garralda, Andrea, Gori, Andrea, Glück, Andreas, Lind, Andreas, Nolla, Anna Carreras, Latiano, Anna, Fracanzani, Anna Ludovica, Peschuck, Anna, Cavallero, Annalisa, Dyrhol-Riise, Anne Ma, Ruello, Antonella, Muscatello, Antonio, Voza, Antonio, Rando-Segura, Ariadna, Solier, Aurora, Cortes, Beatriz, Mateos, Beatriz, Nafria-Jimenez, Beatriz, Schaefer, Benedikt, Bellinghausen, Carla, Ferrando, Carlos, de la Horra, Carmen, Quereda, Carmen, Scollo, Chiara, Lange, Christoph, Hu, Cinzia, Paccapelo, Cinzia, Angelini, Claudio, Cappadona, Claudio, Bianco, Cristiana, Cea, Cristina, Sancho, Cristina, Hoff, Dag Arne Lihaug, Galimberti, Daniela, Haschka, David, Jiménez, David, Pestaña, David, Toapanta, David, Muñiz-Diaz, Eduardo, Azzolini, Elena, Sandoval, Elena, Binatti, Eleonora, Scarpini, Elio, Casalone, Elisabetta, Urrechaga, Eloisa, Paraboschi, Elvezia Maria, Pontali, Emanuele, Reverter, Enric, Calderón, Enrique J., Navas, Enrique, Contro, Ernesto, Arana-Arri, Eunate, Aziz, Fátima, Sánchez, Félix García, Ceriotti, Ferruccio, Martinelli-Boneschi, Filippo, Peyvandi, Flora, Blasi, Francesco, Malvestiti, Francesco, Medrano, Francisco J., Mesonero, Francisco, Rodriguez-Frias, Francisco, Müller, Fredrik, 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Valsecchi, Maria G., Hernandez-Tejero, María, Vehreschild, Maria J. 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T., Manunta, Maria, Acosta-Herrera, Marialbert, D’Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Marquié, Marta, Castoldi, Massimo, Cecconi, Maurizio, Tomasi, Melissa, Boada, Mercè, Joannidis, Michael, Mazzocco, Michela, Ciccarelli, Michele, Rodríguez-Gandía, Miguel, Bocciolone, Monica, Miozzo, Monica, Ayo, Natale Imaz, Blay, Natalia, Chueca, Natalia, Montano, Nicola, Martínez, Nilda, Cornely, Oliver A., Palmieri, Orazio, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Tentorio, Paolo, Castro, Pedro, Rodrigues, Pedro M., Izquierdo-Sanchez, Laura, España, Pedro Pablo, Hoffmann, Per, Bacher, Petra, de Pablo, Raúl, Ferrer, Ricard, Gualtierotti, Roberta, Gallego-Durán, Rocío, Nieto, Rosa, Carpani, Rossana, Morilla, Rubén, Badalamenti, Salvatore, Haider, Sammra, Ciesek, Sandra, Bombace, Sara, Marsal, Sara, Klein, Sebastian, Pelusi, Serena, Wilfling, Sibylle, Goerg, Siegfried, Bosari, Silvano, Brunak, Søren, Heilmann-Heimbach, Stefanie, Aliberti, Stefano, Dudman, Susanne, Zheng, Tenghao, Bahmer, Thomas, Pumarola, Tomas, Cejudo, Trinidad Gonzalez, Rimoldi, Valeria, Monzani, Valter, Skogen, Vegard, Friaza, Vicente, Andrade, Victor, Moreno, Victor, Peter, Wolfgang, Farre, Xavier, Khodamoradi, Yascha, Grimsrud, Marit M., May, Sandra, Colombo, Alicia, Virginia, Monardes-Ramírez A., Dorador, Cristina, Fuentes-Guajardo, Macarena, Silva, Andrea X., Espinosa-Parrilla, Yolanda, Yáñez, Cristian E., Retamales-Ortega, Rocío M., Saez Hidalgo, Juan M., Tobar-Calfucoy, Eduardo A., Carvajal-Silva, Laura, Martínez, Matías F., Cerpa, Leslie C., Christian, Muñoz A., Cappelli, Claudio, Valenzuela-Jorquera, Hector, Zapata-Contreras, Daniela, Zuñiga-Pacheco, Paula, Nova-Lamperti, Estefania A., Sanhueza, Sergio A., Donoso, Gerardo, Bocchieri, Pamela, Kochifas, Pia, Quiñones, Luis A., Pedersen, Ole Birger, Geller, Frank, Westergaard, David, Sequeros, Celia Burgos, Nissen, Janna, Nielsen, Susanne Dam, Feldt-Rasmussen, Ulla, Bliddal, Sofie, Grønbæk, Kirsten, Ullum, Henrik, Ostrowski, Sisse Rye, Feenstra, Bjarke, Shahin, Doaa, Sobh, Ali, Shoma, Ashraf, Nkambul, Lindokuhle, Elhadidy, Tamer A., Abd Elghafar, Mohamed S., El-Jawhari, Jehan J., Mohamed, Attia A. S., Elnagdy, Marwa H., Samir, Amr, Abdel-Aziz, Mahmoud, Khafaga, Walid T., El-Lawaty, Walaa M., Torky, Mohamed S., El-Shanshory, Mohamed R., Elzeiny, Ahmed, Rashad, Amal, Mansour, Tamer A., Yassen, Amr M., Hegazy, Mohamed A. F., Okasha, Kamal, Eid, Mohammed A., Hanteera, Moahmed S., Medina-Gomez, Carolina, Ikram, M. Arfan, Uitterlinden, Andre G., Ripatti, Samuli, Jermy, Bradley, Ruotsalainen, Sanni, Kristiansson, Kati, Koskelainen, Sami, Perola, Markus, Donner, Kati, Kivinen, Katja, Palotie, Aarno, Kaunisto, Mari, Julienne, Hanna, Aschard, Hugues, Deleuze, Jean-Francois, Debette, Stephanie, Tregouet, David-Alexandre, Abel, Laurent, Henches, Léo, Lefloch, Edith, Claire, Dandine-Roulland, Sakuntabhai, Anavaj, Bourgeron, Thomas, Olaso, Robert, Daian, Delphine Bacq, Pellegrin, Isabelle, Casanova, Jean-Laurent, Cobat, Aurélie, Jouanguy, Emmanuelle, Zhang, Qian, Ghosn, Jade, Mentré, France, Laouénan, Cédric, Tubiana, Sarah, Chirouze, Catherine, Quintana-Murci, Luis, Patin, Etienne, Duffy, Darragh, Boland, Anne, Carreras, Anna, Galván-Femenía, Iván, Farré, Xavier, Cortés, Beatriz, Mercader, Josep Maria, Guindo-Martinez, Marta, Torrents, David, Garcia-Aymerich, Judith, Castaño-Vinyals, Gemma, Dobaño, Carlota, van Heel, David A., Hunt, Karen A., Trembath, Richard C., Jacobs, Benjamin Meir, Huang, Qin Qin, Martin, Hilary C., Mason, Dan, Trivedi, Bhavi, Wright, John, Munisamy, Malathy, Finer, Sarah, Griffiths, Christopher J., McCarthy, Mark I., Rosenberger, Carrie, Lee, Jong Eun, Chang, Diana, Hammer, Christian, Hunkapiller, Julie, Mahajan, Anubha, Pendergrass, Rion, Sucheston-Campbell, Lara, Yaspan, Brian, Lee, Hyun Soo, Shin, Eunsoon, Jang, Hye Yoon, Kim, Sunmie, Kym, Sungmin, Kim, Yeon-Sook, Jeong, Hyeongseok, Kwon, Ki Tae, Kim, Shin-Woo, Kim, Jin Yong, Jang, Young Rock, Kim, Hyun ah, Lee, Ji yeon, Lee, Jeong Eun, Lee, Shinwon, Choe, Kang-Won, Kang, Yu Min, Jee, Sun Ha, Jung, Keum Ji, Park, Hyun-Young, Kim, Bong-Jo, Kim, Young Jin, Hwang, Mi Yeong, Yoon, Kyungheon, Pairo-Castineira, Erola, Rawlik, Konrad, Caulfield, Mark J., Baillie, J. Kenneth, Griffiths, Fiona, Bretherick, Andrew D., Stuckey, Alex, Odhams, Christopher A., Walker, Susan, Russell, Clark D., Malinauskas, Tomas, Wu, Yang, Shen, Xia, Elliott, Katherine S., Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Fawkes, Angie, Murphy, Lee, Vitart, Veronique, Wilson, James F., Yang, Jian, Scott, Richard H., Moutsianas, Loukas, Law, Andy, Begg, Colin, Hendry, Sara Clohisey, Hinds, Charles, Horby, Peter, Knight, Julian, Ling, Lowell, Maslove, David, McAuley, Danny, Millar, Johnny, Montgomery, Hugh, Nichol, Alistair, Openshaw, Peter J. M., Ponting, Chris P., Rowan, Kathy, Semple, Malcolm G., Shankar-Hari, Manu, Summers, Charlotte, Walsh, Timothy, Pan, Jacqueline, Grau, Neus, Jones, Tim Owen, Lim, Rosario, Marotti, Martina, Whitton, Christopher, Bociek, Aneta, Campos, Sara, Arbane, Gill, Ostermann, Marlies, Cha, Mina, DAmato, Fabiola, Kosifidou, Eirini, Lorah, Shelley, Morera, Kyma, Brady, Laura, Hugill, Keith, Henning, Jeremy, Bonner, Stephen, Headlam, Evie, Jones, Jessica, List, Abigail, Morley, Joanne, Welford, Amy, Kamangu, Bobette, Ratnakumar, Anitha, Shoremekun, Abiola, Alldis, Zoe, Astin-Chamberlain, Raine, Bibi, Fatima, Biddle, Jack, Blow, Sarah, Bolton, Matthew, Borra, Catherine, Bowles, Ruth, Burton, Maudrian, Choudhury, Yasmin, Cox, Amber, Easthope, Amy, Ebano, Patrizia, Fotiadis, Stavros, Gurasashvili, Jana, Halls, Rosslyn, Hartridge, Pippa, Kallon, Delordson, Kassam, Jamila, Lancoma-Malcolm, Ivone, Matharu, Maninderpal, May, Peter, Mitchelmore, Oliver, Newman, Tabitha, Patel, Mital, Pheby, Jane, Pinzuti, Irene, Prime, Zoe, Prysyazhna, Oleksandra, Shiel, Julian, Taylor, Melanie, Tierney, Carey, Zongo, Olivier, Wood, Suzanne, Zak, Anne, Collier, David, Mundy, Manuela, Thompson, Christopher, Pritchard, Lisa, Gellamucho, Minnie, Cartlidge, David, Bandla, Nageswar, Bailey, Lucy, Davies, Michelle, Delaney, Jane, Scott, Leanne, Abdelrazik, Marwa, Alasdair, Frater, Carter, David, Elhassan, Munzir, Ganesan, Arunkumar, Jenkins, Samuel, Lamond, Zoe, Purohit, Dharam, Rohit, Kumar, Saleem, Malik, Wall, Alanna, Xavier, Kugan, Bakthavatsalam, Dhanalaksmi, Gehad, Kirolos, Gnanapragasam, Pakeerathan, Jain, Kapil, Jain, Swati, Malik, Abdul, Pappachan, Naveen, Moreno-Cuesta, Jeronimo, Haldeos, Anne, Vincent, Rachel, Oziegb, Maryjane, Cavazza, Anna, Cockrell, Maeve, Corcoran, Eleanor, Depante, Maria, Finney, Clare, Jerome, Ellen, Knighton, Abigail, Nayak, Monalisa, Pappa, Evita, Saha, Rohit, Saha, Sian, Dodd, Andrew, O’Reilly, Kevin, McPhail, Mark, Clarey, Emma, Noble, Harriet, Smith, John, Coghlan, Phoebe, Brett, Stephen, Gordon, Anthony, Templeton, Maie, Antcliffe, David, Banach, Dorota, Darnell, Sarah, Fernandez, Ziortza, Jepson, Eleanor, Mohammed, Amal, Rojo, Roceld, Arias, Sonia Sousa, Gurung, Anita Tamang, Wong, Jenny, Fernandez-Roman, Jaime, Hamilton, David O., Johnson, Emily, Johnston, Brian, Martinez, Maria Lopez, Mulla, Suleman, Waite, Alicia A. C., Williams, Karen, Waugh, Victoria, Welters, Ingeborg, Emblem, Jessica, Norris, Maria, Shaw, David, Bashyal, Archana, Beer, Sally, Hutton, Paula, McKechnie, Stuart, Davidson, Neil, Mathew, Soya, Readion, Grace, Ryu, Jung, Wilson, Jean, Agrawal, Shruti, Elston, Kay, Jones, Megan, Meaney, Eoghan, Polgarova, Petra, Elbehery, Muhammad, Daubney, Esther, Ng, Anthony, Marshall, Jocelyn, Pathan, Nazima, Stroud, Katerina, White, Deborah, Andrew, Angela, Ashraf, Saima, Clark, Amy, Dent, Martin, Langley, Margaret, Peters, Cecilia, Ryan, Lucy, Sampson, Julia, Wei, Shuying, Baddeley, Alice, Meredith, Megan, Morris, Lucy, Gibbons, Alexandra, McLoughlin, Lisa, Delgado, Carlos Castro, Clark, Victoria, Dawson, Deborah, Ding, Lijun, Durrant, Georgia, Ezeobu, Obiageri, Harrison, Abiola, Hurt, William James, Kanu, Rebecca, Kinch, Ashley, Leaver, Susannah, Lisboa, Ana, Mathew, Jisha, Patel, Kamal, Saluzzio, Romina Pepermans, Rawlins, John, Samakomva, Tinashe, Shah, Nirav, Sicat, Christine, Texeira, Joana, Queiroz, Joana Gomes De, Gloria, Edna Fernandes Da, Maccacari, Elena, Yun, Nikki, Manna, Soumendu, Farnell-Ward, Sarah, Maizcordoba, Maria, Thanasi, Maria, Ali, Hawakin Haji, Hastings, Janice, Grauslyte, Lina, Hussain, Musarat, Ruge, Bobby, King, Sam, Pogreban, Tatiana, Rosaroso, Lace, Smith, Helen, Phull, Mandeep-Kaur, Adams, Nikkita, Franke, George, George, Aparna, Salciute, Erika, Wong, Joanna, Dunne, Karen, Flower, Luke, Sharland, Emma, Sra, Sukhmani, Andrew, Gillian, Callaghan, Marie, Barclay, Lucy, Marshall, Lucy, Amamio, Maria, Birch, Sophie, Briton, Kate, Clark, Sarah, Doverman, Katerine, Hope, Dave, Mcculloch, Corrienne, Simpson, Scott, Singleton, Jo, Fernandez, Rita, Allen, Meryem, Baptista, David, Crowe, Rebecca, Fox, Jonathan, Khera, Jacyntha, Loveridge, Adam, McKenley, India, Morino, Eriko, Naranjo, Andres, O’Connor, Denise, Simms, Richard, Sollesta, Kathryn, Swain, Andrew, Venkatesh, Harish, Herdman-Grant, Rosie, Joseph, Anna, Nown, Angela, Rose, Steve, Pogson, David, Boxall, Helen, Brimfield, Lutece, Claridge, Helen, Daly, Zoe, George, Shenu, Gribbin, Andrew, Cheema, Yusuf, Cutler, Sean, Richards, Owen, Roynon-Reed, Anna, Cherian, Shiney, Heron, Anne Emma, Williams, Gemma, Szakmany, Tamas, Waters, Abby, Collins, Kim, Dunhill, Jill, Jones, Ffion, Morris, Rebecca, Ship, Lucy, Cardwell, Amy, Ali, Syamlan, Bhatterjee, Ravi, Bolton, Rachel, Chukkambotla, Srikanth, Coleman, Dabheoc, Dalziel, Jack, Dykes, Joseph, Fine, Christopher, Gay, Bethan, Goddard, Wendy, Goodchild, Drew, Harling, Rhiannan, Hijazi, Muhammad, Keith, Sarah, Khan, Meherunnisa, Matt, Roseanna, Ryan-Smith, Janet, Saad, Samuel, Springle, Philippa, Thomas, Jacqueline, Truman, Nick, Kazi, Aayesha, Smith, Matthew, Collier, Heather, Davison, Chloe, Duberley, Stephen, Hargreaves, Jeanette, Hartley, Janice, Patel, Tahera, Smith, Ellen, Kent, Alissa, Goodwin, Emma, Zaki, Ahmed, Tibke, Clare, Hopkins, Susan, Gerrard, Hywel, Jackson, Matthew, Bennett, Sara, Marsh, Liane, Mills, Rebecca, Bell, Jessica, Campbell, Helen, Dawson, Angela, Dodds, Steve, Duffy, Stacey, Gallagher, Lisa, McCafferty, Gemma, Short, Stacey, Smith, Tracy, Thomas, Kirsty, Walker, Claire, Reynolds, Jessica, Yates, Bryan, McKie, Hayley, Panteli, Maria, Thompson, Maria, Waddell, Gail, Beger, Sarah De, Abraheem, Azmerelda, Dunmore, Charlie, Girach, Rumanah, Jones, Rhianna, London, Emily, Nagra, Imrun, Nasir, Farah, Sainsbury, Hannah, Smedley, Clare, Brearey, Stephen, Burchett, Caroline, Cawley, Kathryn, Faulkner, Maria, Jeffrey, Helen, Bamford, Peter, Shaikh, Firdaus, Slack, Lauren, Davies, Angela, Brooke, Hollie, Suarez, Jose Cebrian, Charlesworth, Ruth, Hansson, Karen, Norris, John, Poole, Alice, Sandhu, Rajdeep, Smithson, Elizabeth, Thirumaran, Muthu, Wagstaff, Veronica, Buckley, Sarah, Sloan, Brendan, Rose, Alastair, Major, Amy, Metcalfe, Alexandra, Almaden-Boyle, Christine, Austin, Pauline, Chapman, Susan, Eros, Alexandre, Cabrelli, Louise, Cole, Stephen, Whyte, Clare, Casey, Matt, Bafitis, Vasileios, Tsinaslanidis, George, George, Cassandra, Khade, Reena, Black, Christopher, Ashok, Sundar Raj, Farley, Sean, Brinkworth, Elaine, Harford, Rachel, Murphy, Carl, Williams, Marie, Newey, Luke, Toghill, Hannah, Lewis, Sophie, Rees, Tabitha, Battle, Ceri, Baker, Mark, Travers, Jenny, Chesters, Karen, Baxter, Nicola, Arnott, Andrew, McCreath, Gordan, McParland, Christopher, Rooney, Laura, Sim, Malcolm, Henderson, Steven, Abel, Lynn, Dalton, Carol, Kennedy-Hay, Sophie, O’Donohoe, Lynn, O’Hare, Megan, Orlikowska, Izabela, Parker, Natasha, McNeela, Fiona, Lyle, Amanda, Hughes, Alistair, Radhakrishnan, Jayachandran, Gibson, Sian, Bancroft, Hollie, Bellamy, Mary, Daglish, Jacqueline, Kadiri, Salma, Moore, Faye, Rhodes, Joanne, Sangombe, Mirriam, Peterkin, Zhane, Scriven, James, Carmody, Margaret, Cottle, Juliet, Peasgood, Emily, de Gordoa, Laura Ortiz-Ruiz, Phillips, Claire, Skinner, Denise, Cinquina, Zoe, Howard, Kate, Joy, Rosie, Roche, Samantha, Birkinshaw, Isobel, Carter, Joseph, Ingham, Jo, Marshall, Nicola, Pearson, Harriet, Scott, Zoe, Dasgin, Jo, Gill, Jaspret, Nilsson, Annette, Bamford, Amy, Hull, Diana, Ahmadhaider, Nafeesah, Bates, Michelle, McGhee, Christopher, Ellis, Hannah, Howe, Gwenllian Sera, Singh, Jayaprakash, Stroud, Natalie, Roche, Lisa, Lynch, Ceri, Deacon, Bethan, Pothecary, Carla, Smeaton, Justyna, Agravante, Kevin, Krishnamurthy, Vinodh, Diaba, Cynthia, John, Lincy, Lim, Lai, Jha, Rajeev, Egan, Jasmine, Felton, Timothy, Glasgow, Susannah, Padden, Grace, Choudhr, Ozerah, Bradley-Potts, Joanne, Moss, Stuart, Lingeswaran, Saejohn, Alexander, Peter, Brandwood, Craig, Fiouni, Sofia, Ward, Luke, Allen, Schvearn, Shaw, Jane, Smith, Christopher, Adanini, Oluronke, Collins, Rebecca, Msiska, Maines, Ofori, Linda, Bhatia, Nikhil, Dolan, Hayley, Brunton, Mark, Caterson, Jess, Coles, Holly, Keating, Liza, Tilney, Emma, Jacques, Nicola, Frise, Matthew, Armistead, Jennifer, Bartley, Shauna, Bhuie, Parminder, Rai, Sabi, Tomkova, Gabriela, Greer, Sandra, Shuker, Karen, Tridente, Ascanio, Dobson, Emma, Hunt, Jodie, Tully, Redmond, Dearden, Joy, Drummond, Andrew, Kamath, Prakash, Bullock, Emily, Mulcahy, Michelle, Munt, Shelia, O’Connor, Grainne, Philbin, Jennifer, Rishton, Chloe, Scott, Chloe, Winnard, Sarah, Hasni, Nurkamalia, Gascoyne, Rachel, Hawes, Joanne, Pritchard, Kelly, Stevenson, Lesley, Whileman, Amanda, Beavis, Sarah, Bishop, Lauren, Cart, Cindy, Dale, Katie, Kelly-Baxter, Mary, Mendelski, Adam, Moakes, Emma, Smith, Rheanna, Woodward, Jan, Wright, Stephanie, Allan, Angela, Botello, Adriana, Liew, Jade, Medhora, Jasmine, Trumper, Erin, Savage, Felicity, Scott, Teresa, Place, Marc, Kaye, Callum, Benyon, Sarah, Marriott, Suzie, Park, Linda, Quinn, Helen, Skyes, Daisy, Zitter, Lily, Baines, Kizzy, Gordon, Elizabeth, Keenan, Samantha, Pitt, Andrew, Duffy, Katharine, Ireland, Jane, Semple, Gary, Turner, Lynne, Cathcart, Susanne, Rimmer, Dominic, Puxty, Alex, Puxty, Kathryn, Hurst, Andrew, Miller, Jennifer, Speirs, Susan, Walker, Lauren, Bradshaw, Zena, Brown, Joanna, Melling, Sarah, Preston, Stephen, Slawson, Nicola, Warden, Scott, Beasley, Alanna, Stoddard, Emma, Benham, Leonie, Cupitt, Jason, Caswell, Melanie, Elawamy, Lisa, Wignall, Ashleigh, Roberts, Belinda, Golding, Hannah, Leggett, Samantha, Male, Michelle, Marani, Martyna, Prager, Kirsty, Williams, Toran, Golder, Kim, Jones, Oliver, Cusack, Rebecca, Bolger, Clare, Burnish, Rachel, Carter, Michael, Jackson, Susan, Salmon, Karen, Biss, Jonathan, Aquino, Maia, Croft, Maria, Frost, Victoria, White, Ian, Govender, Keshnie, Webb, Natasha, Stapleton, Liana, Wells, Colin, Nikitas, Nikitas, Sanchez - Rodriguez, Ana, Spencer, Kayleigh, Stowe, Bethan, Izzard, Yvonne, Poole, Michelle, Monnery, Sonja, Trotman, Sallyanne, Beech, Valerie, Combes, Edward, Joefield, Teishel, Covernton, Patrick, Savage, Sarah, Woodward, Elizabeth, Camsooksai, Julie, Reschreiter, Henrik, Barclay, Charlotte, DeAth, Yasmin, Dube, Judith, Humphrey, Charlotte, Jenkins, Sarah, Langridge, Emma, Milne, Rebecca, Wadams, Beverley, Woolcock, Megan, Brett, Michael, Digby, Brian, Gemmell, Lisa, Hornsby, James, MacGoey, Patrick, O’Neil, Pauline, Price, Richard, Sundaram, Radha, Rodden, Natalie, Thomson, Nicola, Rooney, Kevin, Currie, Susan, Henderson, Philip, Ogg, Bethan, Whiteley, Simon, Wilby, Liz, Long, Kate, Matthew, Shailamma, Salada, Sheila, Trott, Susan, Watts, Sarah, Friar, Zoe, Speight, Abigail, Bastion, Victoria, Chandna, Humza, Djeugam, Brice, Haseeb, Muhammad, Kent, Harriet, Lubimbi, Gamu, Murdoch, Sophie, Thomas, Alastair, David, Beena, Lorusso, Rachel, Vochin, Ana, Penacerrada, Melchizedek, Wulandari, Retno, Heath, Charlotte, Jakkula, Srinivas, Morris, Anna, Ahmed, Ashar, Nune, Arvind, Buttriss, Claire, Whitaker, Emma, Davey, Miriam, Golden, David, Acklery, Amy, Fernandes, Fabio, Seaman, Bec, Earl, Victoria, Collins, Amy, Khaliq, Waqas, Adam, Rachel, Treus, Estefania, Holland, Sarah, Alfonso, Jordan, Blackledge, Bethan, Bruce, Michelle, Durrans, Laura Jayne, Eltayeb, Ayaa, Harris, Jade, Hey, Samuel, Hruska, Martin, Lamb, Thomas, Rothwell, Joanne, Fitzgerald, Adele, Lindergard, Gabriella, T-Michael, Helen, Duncan, Tracey, Baxter-Dore, Sharon, Cooper, Lisa, Fox, Claire, Guerin, Jacinta, Hodgkiss, Tracey, Connolly, Karen, McAlinden, Paul, Bridgett, Victoria, Fearby, Maggie, Gulati, A., Hanson, Helen, Kelly, Sinead, McCormack, Louise, Nixon, Rachel, Robinson, Philip, Slater, Victoria, Stephenson, Elaine, Webster, Andrea, Webster, K., Hays, Carole, Hudson, Anne, Patel, Bijal, Clement, Ian, Davis, John, Francis, Sarah, Jerry, Douglas, Abernathy, Caroline, Foster, Louise, Gratrix, Andrew, Cabral-Ortega, Llucia, Hines, Matthew, Martinson, Victoria, Stones, Elizabeth, Winter, Karen, Barrow, Esther, Wylie, Katharine, Baines, Deborah, Birchall, Katie, Kolakaluri, Laurel, Clark, Richard, Sukumaran, Anila, Barker, Melanie, Paripoorani, Deborah, Smith, Lara, Taylor, Charlotte, Downes, Charlotte, Hayman, Melanie, Riches, Katie, Daniel, Priya, Subramanian, Deepak, Holding, Kathleen, Hilton, Mary, Mcdonald, Carly, Richardson, Georgina, Halladay, Georgia, Harding, Peter, Reddy, Amie, Turner-Bone, Ian, Wilding, Laura, Parker, Robert, Lloyd, Michaela, Smith, Leanne, Kelly, Charlie, Lazo, Maria, Neal, Alan, Walton, Olivia, Melville, Julie, Naisbitt, Jay, Joseph, Rosane, Callam, Sara, Hudig, Lisa, Keshet-Price, Jocelyn, Stammers, Katie, Convery, Karen, Randell, Georgina, Fottrell-gould, Deirdre, Mwaura, Esther, Sutherland, Sara-Beth, Stewart, Richard, Mew, Louise, Wren, Lynn, Thrasyvoulou, Laura, Willis, Heather, Hopkins, Bridget, Lenton, Daniel, Roberts, Abigail, Bokhari, Maria, Lucas, Rachael, McCormick, Wendy, Ritzema, Jenny, Linnett, Vanessa, Sanderson, Amanda, Wild, Helen, Flanagan, Rebecca, Hull, Robert, Rhead, Kat, McKenna, Emma, Hughes, Gareth, Anderson, Jennifer, Jones, Kelly, Latham, Scott, Riley, Heather, Coulding, Martina, Clark, Martyn, McCormick, Jacqueline, Mercer, Oliver, Potla, Darsh, Rehman, Hafiz, Savill, Heather, Turner, Victoria, Jude, Edward, Kilroy, Susan, Apetri, Elena, Basikolo, Cathrine, Catlow, Laura, Collis, Matthew, Doonan, Reece, Harvey, Alice, Knowles, Karen, Lee, Stephanie, Lomas, Diane, Lyons, Chloe, McMorrow, Liam, Michael, Angiy, Pendlebury, Jessica, Perez, Jane, Poulaka, Maria, Proudfoot, Nicola, Slevin, Kathryn, Thomas, Vicky, Walker, Danielle, Dark, Paul, Charles, Bethan, McLaughlan, Danielle, Slaughter, Melanie, Horner, Dan, Marsden, Tracy, Andrews, Joyann, Beech, Emily, Akinkugbe, Olugbenga, Bamford, Alasdair, Belfield, Holly, Jones, Gareth A. L., McHugh, Tara, Meghari, Hamza, Ray, Samiran, Tomas, Ana Luisa, O’Neill, Lauran, Peters, Mark, Bell, Michael, Benkenstein, Sarah, Chisholm, Catherine, Davies, Charlene, Kupiec, Klaudia, Payne, Caroline, Halls, Joanna, Blakemore, Hayley, Goff, Elizabeth, Hayes, Kati, Smith, Kerry, Stephens, Deanna, Worner, Ruth, Borislavova, Borislava, Faulkner, Beverley, Thomas, Matt, Cookson, Ruth, Gendall, Emma, Larman, Georgina, Pope, Rebecca, Smalira, Artur, Priestley, Victoria, Cosier, Tracey, Millen, Gemma, Rand, James, Schumacher, Natasha, Sandhar, Roxana, Weston, Heather, Richardson, Neil, Cooper, Lucy, Jones, Cathy, Huang, Ya-Wen Jessica, Jacob, Reni, Denmade, Craig, Mcintyre, Lewis, Trodd, Dawn, Martin, Jane, Watson, Geoff, Bevan, Emily, Wreybrown, Caroline, Bano, Shereen, Bellwood, Ruth, Bentley, Michael, Bromley, Matt, Gurr, Lucy, Ledgard, Camilla, McGowan, Janet, Pye, Kate, Sellick, Kirsten, Stacey, Amelia, Warren, Deborah, Wilkinson, Brian, Akeroyd, Louise, Shafique, Huma, Morgan, James, Shorter, Susan, Swinger, Rachel, Waters, Emily, Lawton, Tom, Allan, Elizabeth, Darlington, Kate, Davies, Ffyon, Davies, Llinos, Easton, Jack, Kumar, Sumit, Lean, Richard, Mackay, Callum, Pugh, Richard, Qiu, Xinyi, Rees, Stephanie, Scanlon, Jeremy, Lewis, Joanne, Menzies, Daniel, Bolger, Annette, Davies, Gwyneth, Davies, Jennifer, Garrod, Esther, Jones, Helen, Manley, Rachel, Williams, Hannah, Frankham, Jordan, Pitts, Sally, White, Nigel, Branney, Debbie, Tiller, Heather, Efford, Georgia, Garland, Zoe, Grimmer, Lisa, Gumbrill, Bethany, Johnson, Rebekah, Sweet, Katie, Bewley, Jeremy, Coleman, Christina, Corcoran, Katie, Morano, Eva Maria Hernandez, Shiel, Rachel, Webster, Denise, Bonnici, Josephine, Daniel, Eleanor, Dell, Abbie, Kent, Melanie, Wilkinson, Ami, Brown, Ellen, Kay, Andrea, Campbell, Suzanne, Cowton, Amanda, Birt, Mark, Greenaway, Vicki, Potts, Kathryn, Hutton, Clare, Shepperson, Andrew, Forsey, Miranda, Nicholson, Alice, Vertue, Mark, Riches, Joanne, Kaliappan, Agilan, Nicholson, Anne, MacCallum, Niall, Raith, Eamon, Bercades, Georgia, Hass, Ingrid, Brealey, David, Martir, Gladys, Reyes, Anna, Smyth, Deborah, Zapatamartinez, Maria, Alvaro, Ana, Jetha, Champa, Ma, Louise, Booker, Lauren, Mostoles, Loreta, Pratley, Anezka, Altabaibeh, Abdelhakim, Parmar, Chetan, Gilbert, Kayleigh, Ferguson, Susie, Shepherd, Amy, Morris, Sheila, Baruah, Rosie, Lloyd, Georgina, Bell, Stephanie, Rivers, Vanessa, Purewal, Bally, Hammerton, Kate, Anderson, Susan, Birch, Janine, Collins, Emma, Oleary, Ryan, Cornell, Sarah, Jarmain, Jordan, Rogerson, Kimberley, Wakinshaw, Fiona, Woods, Lindsey, Rostron, Anthony, Elcioglu, Zeynep, Roy, Alistair, Bell, Gillian, Dickson, Holly, Wilcox, Louise, Katary, Amro, English, Katy, Hutter, Joanne, Pawley, Corinne, Doble, Patricia, Shovelton, Charmaine, Vaida, Marius, Purnell, Rebecca, Thomas, Ashly, Cagova, Lenka, Fofano, Adama, Holcombe, Helen, Mitchell, Alice Michael, Mwaura, Lucy, Praman, KrithivasanÂ, Garnr, Lucie, Mepham, Sue, Paques, Kitty, Vuylsteke, Alain, Mackie, Jennifer, Pearn, Carmen, Zamikula, Julie, Nyirenda, Maggie, Capozzi, Lisa, Reece-Anthony, Rosie, Noor, Hazma, Nilo, Alfa Cresia, Grove, Michelle, Daniel, Amelia, Finn, Joanne, White, Nikki, Saha, Rajnish, Badal, Bibi, Ixer, Karen, Duffin, Donna, Player, Ben, Hill, Helen, Cole, Jade, Brooks, Jenny, Davies, Rhys, Hunt, Lauren, Thomas, Emma, Williams, Angharad, Oblak, Metod, Thankachen, Mini, Irisari, Jamie, Sayan, Amrinder, Popescu, Monica, Finch, Cheryl, Jamieson, Andrew, Quinn, Alison, Cooper, Joshua, Liderth, Sarah, Waddington, Natalia, Burn, Iona, Manso, Katarina, Penn, Ruth, Tebbutt, Julie, Thornton, Danielle, Winchester, James, Hambrook, Geraldine, Shanmugasundaram, Pradeep, Craig, Jayne, Simpson, Kerry, Higham, Andrew, Sibbett, Louise, Paine, Sheila, Reed, Annabel, Conyngham, Jo-Anna, Mupudzi, Mcdonald, Thomas, Rachel, Wright, Mary, Griffin, Denise, Partridge, Richard, Corral, Maria Alvarez, Muchenje, Nycola, Sitonik, Mildred, Butler, Aaron, Folkes, Linda, Fox, Heather, Gardner, Amy, Helm, David, Hobden, Gillian, King, Kirsten, Margalef, Jordi, Margarson, Michael, Martindale, Tim, Meadows, Emma, Raynard, Dana, Thirlwall, Yvette, Baird, Yolanda, Gomez, Raquel, Martin, Darren, Hodgson, Luke, Corin, Clinton, Sidall, Erikka, Szabo, Densie, Floyd, Sharon, Davies, Hannah, Austin, Karen, Kelsall, Olivia, Wood, Hannah, Cornell, Thomas, Ralph, Kate, Bean, Sarah, Burt, Karen, Spivey, Michael, Richards, Carol, Tedstone, Rachel, Carmody, Siobhain, Zhao, Xiaobei, Page, Valerie, Guanco, Mark Louie, Hoxha, Elvira, Zorloni, Camilla, Dean, Charlotte, Jones, Emma, Carter, Emma, Dunn, Joshua, Kong, Thomas, Mahenthran, Mervin, Marsh, Chris, Holland, Maureen, Keenan, Natalie, Mahmoud, Mohamed, Lyons, Marc, Wassall, Helen, Young, Meghan, Bradley, Paul, Burda, Dorota, Donlon, Sinead, Harden, Lesley, Harris, Celia, Mayangao, Irving, Montaser, Rugia, Mtuwa, Sheila, Piercy, Charles, Smith, Eleanor, Stone, Sarah, Verula, Jerik, Blackman, Helen, Marriott, Cheryl, Michalak, Natalia, Creagh-Brown, Ben, Salberg, Armorel, Boyer, Naomi, Pristopan, Veronika, Maynard, Victoria, Walker, Rachel, Hormis, Anil, Collier, Dawn, Graham, Cheryl, McCormick, Jake, Warrington, Jake, Cosgrove, Denise, McFarland, Denise, Ratcliffe, Judith, Charnock, Rob, Wynter, Inez, Gill, Mandy, Kirk, Jill, Paul, Paul, Ratnam, Valli, Shelton, Sarah, Jardine, Catherine, Hay, Alasdair, Williams, Dewi, Durga, Latha, Hibbert, Meg, Kennard-Holden, Gareth, Woodford, Chrsitopher, Tetla, Dariusz, Price, Alicia, Thomas, Alice, Thorpe, Chris, Knights, Ellen, Ward, Donna, Laha, Shondipon, Verlander, Mark, Williams, Alexandra, Prout, Rachel, Langton, Helen, Watters, Malcolm, Hunt, Charlotte, Novis, Catherine, Arif, Sarwat, Cunningham, Amy, Hewitt, Claire, Hindale, Julia, Jackson-Lawrence, Karen, Shepardson, Sarah, Wills, Maryanne, Butler, Susie, Tavares, Silivia, Barber, Russell, Hilldrith, Annette, Hubbard, Kelly, Egginton, Dawn, Clark, Michele, Purvis, Sarah, Sinclair, Simon, Collins, Vicky, Landeg, Bethan, Sell, Craig, Coetzee, Samantha, Gales, Alistair, Otahal, Igor, Icke, Becky, Raj, Meena, Williams, Caroline, Williams, Jill, Hill, Lucy, Kayani, Abdul, Masunda, Bridgett, Gondo, Prisca, Atayeva, Nigara, Cruz, Carina, Pattison, Natalie, Burnett, Caroline, Hatton, Jonathan, Heeney, Elaine, Newton, Maria, Al-Moasseb, Hassan, Behan, Teresa, Player, Jasmine, Stead, Rachael, Mitra, Atideb, Nauyokas, Kirsty, Humphreys, Sally, Cockerill, Helen, Tampsett, Ruth, Postovalova, Evgeniya, Coventry, Tina, McGregor, Amanda, Fowler, Susan, Macmahon, Mike, Cochrane, Patricia, Pirie, Sandra, Hanley, Sarah, Ali, Asifa, Brady, Megan, Dale, Sam, Dance, Annalisa, Gledhill, Lisa, Greig, Jill, Hanson, Kathryn, Holdroyd, Kelly, Home, Marie, Ishaq, Tahira, Kelly, Diane, Matapure, Lear, Melia, Deborah, Mellor, Samantha, Merwaha, Ekta, Nortcliffe, Tonicha, Shaw, Lisa, Shaw, Ryan, Wood, Tracy, Bayo, Lee-Ann, Usher, Miranda, Wilson, Alison, Kitson, Ross, Pinnell, Jez, Robinson, Matthew, Boltwood, Kaitlin, Birch, Jenny, Bough, Laura, Tutton, Rebecca, Winter-Goodwin, Barbara, Goodsell, Josie, Taylor, Kate, Williams, Patricia, Williams, Sarah, Cave, Ashleigh, Rees, James, Imeson-Wood, Janet, Smith, Jacqueline, Amin, Vishal, Karthik, Komala, Kausar, Rizwana, Anastasescu, Elena, Reid, Karen, Anumakonda, Vikram, Stoddart, Ella, Demetriou, Carrie, Eckbad, Charlotte, Howie, Lucy, Mitchard, Sarah, Ramos, Lidia, White, Katie, Hierons, Sarah, Kelly, Fiona, Serrano-Ruiz, Alfredo, Evans, Gabrielle, Nicol, Liz, Wilkins, Joy, Hulacka, Kim, Debreceni, Gabor, Brown, Alison, Crickmore, Vikki, Hill, Kay, Kannan, Thogulava, Dagutao, Zenaida, Beesley, Kate, Lewis, Alison, Perry, Jess, Antony, Sherly, Board, Sarah, Buckley, Clare, Pippard, Lucy, Tanate, Alfonso, Wood, Diane, Kubisz-Pudelko, Agnieska, Gouda, Ayman, Auld, Fiona, Donnachie, Joanne, Murdoch, Euan, Prentice, Lynn, Runciman, Nikole, Senaratne, Dhaneesha, Short, Abigail, Sweeney, Laura, Symon, Lesley, Todd, Anne, Turner, Patricia, McCann, Erin, Salutous, Dario, Edmond, Ian, Whitelaw, Lesley, Bland, Yvonne, Kajtor, Istvan, Kavanagh, Lisa, Singler, Karen, Linfield-Brown, George, Moore, Luke Stephen Prockter, Vizcaychipi, Marcela, Martins, Laura, Moore, Luke, Bull, Rhian, Carungcong, Jaime, Allen, Louise, Beranova, Eva, Knight, Alicia, Price, Carly, Tilbey, Sorrell, Turney, Sharon, Hazelton, Tracy, Tutt, Gabriella, Arora, Mansi, Turki, Salah, Sinfield, Emily, Deery, Joanne, Ramos, Hazel, Cristiano, Daniele, Dormand, Natalie, Farzad, Zohreh, Gummadi, Mahitha, Salmi, Sara, Sloane, Geraldine, Varghese, Mathew, Thwaites, Vicky, Patel, Brijesh, Kamal, Liyanage, Zborowski, Anelise Catelan, Coe, Ryan, Anderson, Madeleine, Beadle, Jane, Coates, Charlotte, Collins, Katy, Crowley, Maria, Johnson, Laura, King, Laura, Paramsothy, Remi, Sargeant, Janet, Silva, Pedro, Stuart, Carmel, Taylor, June, Tyl, David, Wakefield, Phillipa, Kamundi, Charlotte, Olufuwa, Olumide, Belagodu, Zakaulla, Gherman, Anca, Oakley, Naomi, Allan, John, Geary, Tim, Meikle, Alistair, O’Brien, Peter, Wood, Stephen, Clark, Andrew, Houston, Gordon, Black, Karen, Clarkson, Michelle, D’Sylva, Stuart, Morrison, Alan, Norman, Kathryn, Taylor, Margaret, Clements, Suzanne, Cohrane, Catriona, Gonzalez, Nora, Strachan, Dominic, Beith, Claire, Moar, Kirsten, Anderson, Peter, Archer, Katie, Burtenshaw, Andrew, Clayton, Sarah, Cother, Naiara, Cowley, Nicholas, Davis, Caroline, Digby, Stephen, Durie, Alison, Harrison, Alison, Low, Emma, McAlindon, Michael, McCurdy, Alex, Morgan, Aled, Rankin, Tobias, Thrush, Jessica, Tranter, Helen, Vigurs, Charlie, Wild, Laura, Murphy, Lorna, Smythe, Michelle, Brickell, Kathy, Ali, Inthakab Ali Mohamed, Beaumont, Karen, Elsaadany, Mohamed, Fernandes, Kay, Ally, Sameena Mohamed, Rangarajan, Harini, Sarathy, Varun, Selvanayagam, Sivarupan, Vedage, Dave, White, Matthew, Coton, Zoe, Joshy, Aricsa, Blunt, Mark, Curgenven, Hollie, Botfield, Liam, Dexter, Catherine, Kuravi, Aditya, Butler, Joanne, Chadwick, Robert, Ranga, Poonam, Richardson, Lisa, Virgilio, Emma, Anwer, Maddiha, Garg, Atul, Botfield, Donna, Marriott, Xana, Stewart, Keely, Mullan, Dee, Gaylard, Jane, Nowak, Justyna, Jones, Sian, Crawley, Rikki, Crew, Abigail, Cunningham, Mishell, Daniels, Allison, Harrison, Laura, Hope, Susan, Lancaster, Nicola, Matthews, Jamie, Wray, Gemma, Inweregbu, Ken, Cutts, Sarah, Miller, Katharine, Brady, Ailbhe, Chan, Rebekah, McIvor, Shane, Prady, Helena, Mathew, Bijoy, Little, Jeff, Furniss, Tim, Wright, Chris, King, Bernadette, Wasson, Christopher, O’Neill, Aisling, Turley, Christine, McGuigan, Peter, Collins, Erin, Finn, Stephanie, Green, Jackie, McAuley, Julie, Nair, Abitha, Quinn, Charlotte, Tauro, Suzanne, Ward, Kathryn, McGinlay, Michael, Reddy, Kiran, Ahmad, Norfaizan, Anderson, Samantha, Barker, Joann, Bauchmuller, Kris, Birchall, Kathryn, Bird, Sarah, Cawthron, Kay, Chetam, Luke, Cole, Joby, Donne, Ben, Foote, David, Ford, Amber, Hanratty, Helena, Harrington, Kate, Hesseldon, Lisa, Housley, Kay, Jackson, Yvonne, Jarman, Claire, Kibutu, Faith, Lenagh, Becky, Macharia, Irene, Masuko, Shamiso, Milner, Leanne, Newell, Helen, Nwafor, Lorenza, Oxspring, Simon, Phillips, Patrick, Raithatha, Ajay, Rowland-Jones, Sarah, Smith, Jacqui, Thompson, Roger, Trower, Helen, Walker, Sara, Watson, James, Wiles, Matthew, Lye, Alison, Willson, Jayne, Mills, Gary, Harris, Sansha, Hartill, Eleanor, Barron, Anthony, Collins, Ciara, Kaul, Sundeep, Nolan, Claire, Polgar, Oliver, Prendergast, Claire, Rogers, Paula, Shokkar, Rajvinder, Woodruff, Meriel, Mahay, Kanta, Reed, Anna, Meyrick, Hayley, Passmore, Heather, Farwell, James, O’Connell, Susan, Gregory, Jane, Barberis, Luigi, Harper, Rosemary, Smith, Tim, Armstrong, Diane, Bowey, Angie, Cowley, Anne, Corner, Andrew, Highgate, Judith, Rutherfurd, Claire, Taylor, Jo-Anne, Goodwin, Sarah, Eapen, Beena, Trim, Fiona, Donnison, Phil, Armstrong, Lisa, Bates, Hayley, Dooks, Emma, Farquhar, Fiona, Kitching, Amy, McParland, Chantal, Packham, Sophie, Hairsine, Brigid, Andreou, Premetie, Hales, Dawn, Mathews, Megha, Patel, Rekha, Barry, Peter, Flint, Neil, Hailstone, Jessica, Ghuman, Navneet, Leonard, Bethany, Lees, Rachel, Butcher, Deborah, Leng, Katy, Butterworth-Cowin, Nicola, O’Sullivan, Susie, Ghosh, Alison, Williams, Emma, Adams, Colene, Agasou, Anita, Arden, Tracie, Beekes, Mandy, Bowes, Amy, Boyle, Pauline, Button, Heather, Carnahan, Mandy, Carter, Anne, Childs, Danielle, Hurford, Fran, Hussain, Yasmin, Javaid, Ayesha, Jones, James, Leigh, Michael, Martin, Terry, Millward, Helen, Motherwell, Nichola, Newman, Julie, Rikunenko, Rachel, Stickley, Jo, Summers, Julie, Ting, Louise, Tivenan, Helen, Donaldson, Denise, Capps, Nigel, Cale, Emily, Jose, Sanal, Osbourne, Wendy, Pajak, Susie, Rankin, Jayne, Tonks, Louise, Baird, Tracy, Harkins, Margaret, Ruddy, Jim, West, Joe, Duffield, Joseph, Mallon, Lewis, Smith, Oliver, Smuts, Sara, Campbell, Andy, Davies, Cate, Davies, Sarah, Hughes, Rachel, Jobes, Lisa, Whitehead, Victoria, Watkins, Clare, Bowman, Fiona, Milligan, Barry, McPherson, Liane, Metherell, Stella, Harris, Nichola, Lake, Victoria, Radford, Elizabeth, Smallwood, Andy, Gopal, Shameer, Vassell, Katherine, Bell, Dina, Boyle, Rosalind, Douglas, Katie, Glass, Lynn, Lennon, Liz, Rattray, Austin, Lee, Emma, Jones, Danielle, Parsons, Penny, Attwood, Ben, Jefferson, Paul, Ranganathan, Mohan, Atwal, Inderjit, Campbell, Bridget, Day, Angela, Stagg, Camilla, Haynes, Emma, Ahmed, Cecilia, Clamp, Sarah, Colley, Julie, Haq, Risna, Hayes, Anne, Joseph, Sibet, Maqsood, Zahira, Hussain, Samia, Hulme, Jonathan, Domingos, Patience, Kumar, Rita, Purewal, Manjit, Taylor, Becky, Bunni, Lara, Latif, Monica, Jennings, Claire, Jose, Shilu, Marshall, Rebecca, Metryka, Aleksandra, Subramanian, Gayathri, Burgoyne, Adam, Tyler, Amanda, Waldron, Joanne, Hilltout, Paula, Evitts, Jayne, Ward, Geraldine, Bremmer, Pamela, Hawkins, Carl, Jackman, Sophie, Ogorek, Michal, Ashby, Kylie, Thornton, Lorraine, Mercer, Pauline, Halkes, Matthew, Revill, Adam, Saint, Bryony, Fletcher, Jo, Netherton, Kimberley, Chablani, Manish, Kirkby, Amy, Roper, Amanda, Szymiczek, Kinga, Sutherland, Isobel, O’Brien, Linda, Connell, Joanne, Davies, Kim, Lewis, Tracy, Omar, Zohra, Perkins, Emma, Sathe, Sonia, Davies, Ellie, Lyon, Alex, Mapfunde, Isheunesu, Willis, Charlotte, Hitchcock, Rachael, Hall, Kathryn, King, Christopher, Fagan, Andrew, Nazari, Roonak, Worsley, Lucy, Allibone, Suzanne, Kasipandian, Vidya, Patel, Amit, Cutting, Parisa, Genetu, Roman, Mac, Ainhi, Murphy, Anthony, Ward, Sinead, Butt, Fatima, Ayers, Amanda, Harrison, Wendy, Mackintosh, Katherine, North, Julie, Ashton, Lydia, Bi, Rehana, Owen, Samantha, Winmill, Helen, Scholefield, Barney, Blowing, Hannah, Williams, Erin, Duskova, Michaela, Edwards, Michelle, Rees, Alun, Thomas, Helen, Brooks, Jolene, Phipps, Janet, Brooks, Suzanne, Dennis, Catherine, Parris, Vicki, Srikaran, Sinduya, Sukha, Anisha, McGregor, Alistair, Tiongson, Gerlynn, Adams, Katie, Andrew, Benedict, Brayne, Adam, Carter, Sasha, Findlay, Louise, Fisher, Emma, Jackson, Peter, Kaye, Duncan, Parkin, Juliet, Tuckey, Victoria, Hunt, Jane, Love, Nicholas, van Koutrick, Lynne, Hanson, Ashley, Dent, Kathy, Horsley, Elizabeth, Pearson, Sandra, Spencer, Sue, Hutchinson, Dorothy, Potoczna, Dorota, Akhtar, Muhammad Nauman, Cottam, Lisa-Jayne, Sanders, Jack, Garcia, Sara Mingo, pakou, Glykeria, Filipe, Helder, Maharajh, Amitaa, de Neef, Mark, Martin, Daniel, Eastgate, Christine, Teoh, Poh Choo, Barrett, Fiona, Bradley, Clare, Donaldson, Avril, Mascarenhas, Mairi, O’Hara, Marianne, Okeefe, Laura, Clarke, Noreen, Whiteside, Jonathan, Campbell, Rachael, Matheson, Joanna, McDonald, Deborah, Patience, Donna, Rice, Polly, Clapham, Melanie, Mutch, Rachel, Craig, Hannah, Poultney, Una, Burns, Karen, Twiss, Sophie, Barton, Janet, George, Linsha, Harrop, Clare, Mathew, Sherly, Wright, David Justin, Harrison, Rachel, Toohie, Jordan, Chandler, Ben, Turnbull, Alison, Mallinson, Janine, Elliott, Kerry, Wolf-Roberts, Rebecca, Tench, Helen, Hobrok, Maria, Loosley, Ronda, McGuinness, Heather, Sims, Tanya, Afolabi, Deborah, Allison, Kathryn Sian, Anderson, Taya, Dore, Rachael, Jones, Dawn, Rogers, Naomi, Saunderson, Paula, Whitbread, Jennifer, O’Malley, Laura, Rad, Laura, Hawcutt, Daniel, Aldridge, Jonathan, Tolson, Melanie, Garrioch, Sweyn, Tomlinson, Joanne, Grosdenier, Michael, Loader, David, Kapoor, Ritoo, Hector, Gemma, Scherewode, Joslan, Sri-Chandana, Chunda, Stephenson, Lorraine, Marsh, Sarah, Rosa, Arnold Dela, Jhanji, Shaman, Bemand, Thomas, Howle, Ryan, Baikady, Ravishankar Rao, Thomas, Benjamin, Black, Ethel, Tatham, Kate, Gurram, Sambasivarao, Watson, Ekaterina, Quaid, Sheena, Saunderson, Anne, O’Brien, Rachel, Moultrie, Sam, Service, Jen, Cheyne, Clare, Odam, Miranda, Wiliams, Alison, Barnes, Nicky, Csabi, Peter, Rocha, Joana Da, Glynou, Louika, Huffenberger, Amy, Bryant, Jade, Pickard, Amy, Roe, Nicholas, Bellini, Arianna, Mayer, Anton, Burrow, Amy, Colley, Natalie, Evans, Jayne, Howlett, Alex, Khalifeh, Zeinab, Pryce, Jerldine, Gorman, Claire, Brady, Rebecca, Timlick, Elizabeth, Antoine, Pierre, Gupta, Abhinhav, Hardy, John, Houlden, Henry, Moncur, Eleanor, Tucci, Arianna, Tariq, Ambreen, Tagliavini, Emma, Ramsay, Becky, Fidler, Katy, Donnelly, Kevin, Hollis, Rebecca, Barr, Jocelyn, Boyd, Elizabeth, Irvine, Val, Shelley, Ben, Buckley, Julie, Hamilton, Charlene, Valdeavella, Kathryn, Bircham, Sarah, Liggett, Steven, Patil, Anand, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Fowler, Tom A., Elliott, Paul, Tenesa, Albert, Aitkin, Emma, Aravindan, Latha, Armstrong, Ruth, Biggs, Heather, Boz, Ceilia, Brown, Adam, Chikowore, Primmy, Coutts, Audrey, Coyle, Judy, Cullum, Louise, Das, Sukamal, Day, Nicky, Donnelly, Lorna, Duncan, Esther, Finernan, Paul, Fourman, Max Head, Furlong, Anita, Furniss, James, Gallagher, Bernadette, Gilchrist, Tammy, Golightly, Ailsa, Hafezi, Katarzyna, Hamilton, Debbie, Hendry, Ross, Kearns, Naomi, Law, Dawn, Law, Rachel, Law, Sarah, Lidstone-Scott, Rebecca, Lauder, Christen, Macgillivray, Louise, Maclean, Alan, Mal, Hanning, McCafferty, Sarah, Mcmaster, Ellie, Meikle, Jen, Moore, Shona C., Murphy, Sheena, Mybaya, Hellen, Oosthuyzen, Wilna, Zheng, Chenqing, Chen, Jiantao, Paterson, Trevor, Tucker, Petra, Schon, Katherine, Stenhouse, Andrew, Das, Mihaela, Swets, Maaike, Szoor-McElhinney, Helen, Taneski, Filip, Turtle, Lance, Wackett, Tony, Ward, Mairi, Weaver, Jane, Wrobel, Nicola, Rakitko, Alexander, Ilinsky, Valery, Yermakovich, Danat, Popov, Iaroslav, Chernitsov, Alexander, Kovalenko, Elena, Vergasova, Ekaterina, Prokhorov, Alexandr, Krasnenko, Anna, Plotnikov, Nikolay, Stetsenko, Ivan, Kim, Anna, Cirulli, Elizabeth T., Schiabor Barrett, Kelly M., Bolze, Alexandre, White, Simon, Washington, Nicole L., Lu, James T., Riffle, Stephen, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Leonetti, Nicole, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Grzymski, Joseph J., Joshi, Madhvi N., Dixit, Raghav D., Shah, Pranay K., Upadhyay, Kamlesh J., Chuhan, Naresh T., Desai, Kairavi J., Shah, Meenakshi R., Modi, Bhavesh, Joshi, Chaitanya G., Pandit, Ramesh J., Singh, Indra, Ansari, Afzal I., Raval, Janvi N., Patel, Zarna Z., Moreno-Estrada, Andres, Vázquez-Pérez, Joel Armando, Castillejos-López, Manuel, Aquino-Gálvez, Arnoldo, Shamah-Levy, Teresa, Ávila-Arcos, María C., Luna, María Teresa Tusié, Hidalgo-Miranda, Alfredo, Barberena-Jonas, Carmina, Quinto-Cortés, Consuelo D., Ávila-Arcos, Marco Antonio, Huerta-Chagoya, Alicia, García-García, Lourdes, Barnetche, Jesús Martinez, Alpuche-Aranda, Celia, Rivera, Juan A., Gutiérrez, Tonatiuh Barrientos, Ochoa-Guzmán, Ana, Ordoñez-Sánchez, Maria Luisa, Segura-Kato, Yayoi, Herrera-Montalvo, Luis Alonso, Mendoza-Vargas, Alfredo, Reyes-Grajeda, Juan Pablo, Cruz-Cruz, Alonso D., Velázquez-Cruz, Rafael, Torres-Espíndola, Luz María, Sierra-Vargas, Martha Patricia, Camarena, Angel, Ruiz, Víctor, Chávez-Alderete, Jaime, Jaime-Capetillo, María Esther, Guadarrama-Pérez, Cristóbal, Zúñiga-Ramos, Joaquin, Olivera-Ramírez, Alejandra, Martínez, Miguel Angel López, Serna-Muñoz, Ricardo, Garmendia, Adriana, Namkoong, Ho, Okada, Yukinori, Imoto, Seiya, Katayama, Kazuhiko, Fukunaga, Koichi, Kitagawa, Yuko, Sato, Toshiro, Hasegawa, Naoki, Kumanogoh, Atsushi, Kimura, Akinori, Ai, Masumi, Tokunaga, Katsushi, Kanai, Takanori, Miyano, Satoru, Ogawa, Seishi, Edahiro, Ryuya, Sonehara, Kyuto, Shirai, Yuya, Ishii, Makoto, Kabata, Hiroki, Masaki, Katsunori, Kamata, Hirofumi, Ikemura, Shinnosuke, Chubachi, Shotaro, Okamori, Satoshi, Terai, Hideki, Tanaka, Hiromu, Morita, Atsuho, Lee, Ho, Asakura, Takanori, Sasaki, Junichi, Morisaki, Hiroshi, Uwamino, Yoshifumi, Nanki, Kosaku, Mikami, Yohei, Tomono, Kazunori, Kato, Kazuto, Matsuda, Fumihiko, Takahashi, Meiko, Hizawa, Nobuyuki, Takeda, Yoshito, Hirata, Haruhiko, Shiroyama, Takayuki, Miyawaki, Satoru, Suzuki, Ken, Maeda, Yuichi, Nii, Takuro, Noda, Yoshimi, Niitsu, Takayuki, Adachi, Yuichi, Enomoto, Takatoshi, Amiya, Saori, Hara, Reina, Takahashi, Kunihiko, Anzai, Tatsuhiko, Hasegawa, Takanori, Ito, Satoshi, Koike, Ryuji, Endo, Akifumi, Uchimura, Yuji, Miyazaki, Yasunari, Honda, Takayuki, Tateishi, Tomoya, Tohda, Shuji, Ichimura, Naoya, Sonobe, Kazunari, Sassa, Chihiro, Nakajima, Jun, Nannya, Yasuhito, Omae, Yosuke, Takahashi, Kazuhisa, Harada, Norihiro, Hiki, Makoto, Takagi, Haruhi, Nakamura, Ai, Tagaya, Etsuko, Kawana, Masatoshi, Arimura, Ken, Ishiguro, Takashi, Takayanagi, Noboru, Isono, Taisuke, Takaku, Yotaro, Takano, Kenji, Anan, Ryusuke, Nakajima, Yukiko, Nakano, Yasushi, Nishio, Kazumi, Ueda, Soichiro, Hayashi, Reina, Tateno, Hiroki, Hase, Isano, Yoshida, Shuichi, Suzuki, Shoji, Mitamura, Keiko, Saito, Fumitake, Ueda, Tetsuya, Azuma, Masanori, Nagasaki, Tadao, Yasui, Yoshinori, Hasegawa, Yoshinori, Mutoh, Yoshikazu, Yoshiyama, Takashi, Shoko, Tomohisa, Kojima, Mitsuaki, Adachi, Tomohiro, Ishikawa, Motonao, Takahashi, Kenichiro, Watanabe, Kazuyoshi, Manabe, Tadashi, Ito, Fumimaro, Fukui, Takahiro, Funatsu, Yohei, Koh, Hidefumi, Hirai, Yoshihiro, Kawashima, Hidetoshi, Narita, Atsuya, Niwa, Kazuki, Sekikawa, Yoshiyuki, Saito, Fukuki, Yoshiya, Kazuhisa, Yoshihara, Tomoyuki, Suzuki, Yusuke, Nakayama, Sohei, Masuzawa, Keita, Nishi, Koichi, Nishitsuji, Masaru, Tani, Maiko, Inoue, Takashi, Hirano, Toshiyuki, Kobayashi, Keigo, Miyazawa, Naoki, Kimura, Yasuhiro, Sado, Reiko, Ogura, Takashi, Kitamura, Hideya, Murohashi, Kota, Nakachi, Ichiro, Baba, Rie, Arai, Daisuke, Fuke, Satoshi, Saito, Hiroshi, Kuwahara, Naota, Fujiwara, Akiko, Okada, Takenori, Baba, Tomoya, Noda, Junya, Mashimo, Shuko, Yagi, Kazuma, Shiomi, Tetsuya, Hashiguchi, Mizuha, Odani, Toshio, Mochimaru, Takao, Oyamada, Yoshitaka, Mori, Nobuaki, Izumi, Namiki, Nagata, Kaoru, Taki, Reiko, Murakami, Koji, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hayashi, Kentaro, Shimizu, Tetsuo, Gon, Yasuhiro, Fujitani, Shigeki, Tsuchida, Tomoya, Yoshida, Toru, Kagaya, Takashi, Kita, Toshiyuki, Sakagami, Satoru, Kimizuka, Yoshifumi, Kawana, Akihiko, Nakamura, Yoshihiko, Ishikura, Hiroyasu, Takata, Tohru, Kikuchi, Takahide, Taniyama, Daisuke, Nakamura, Morio, Kodama, Nobuhiro, Kaneyama, Yasunari, Maeda, Shunsuke, Nagasaki, Yoji, Okamoto, Masaki, Ishihara, Sayoko, Ito, Akihiro, Chihara, Yusuke, Takeuchi, Mayumi, Onoi, Keisuke, Hashimoto, Naozumi, Wakahara, Keiko, Ando, Akira, Masuda, Makoto, Wakabayashi, Aya, Watanabe, Hiroki, Sageshima, Hisako, Nakada, Taka-Aki, Abe, Ryuzo, Shimada, Tadanaga, Kawamura, Kodai, Ichikado, Kazuya, Nishiyama, Kenta, Yamasaki, Masaki, Hashimoto, Satoru, Kusaka, Yu, Ohba, Takehiko, Isogai, Susumu, Takada, Minoru, Kanda, Hidenori, Komase, Yuko, Sano, Fumiaki, Asano, Koichiro, Oguma, Tsuyoshi, Harada, Masahiro, Takahashi, Takeshi, Shibusawa, Takayuki, Abe, Shinji, Kono, Yuta, Togashi, Yuki, Izumo, Takehiro, Inomata, Minoru, Awano, Nobuyasu, Ogawa, Shinichi, Ogata, Tomouki, Ishihara, Shoichiro, Kanehiro, Arihiko, Ozaki, Shinji, Fuchimoto, Yasuko, Kitagawa, Yuichiro, Yoshida, Shozo, Ogura, Shinji, Nishiyama, Kei, Yoshida, Kousuke, Beppu, Satoru, Fukuyama, Satoru, Eriguchi, Yoshihiro, Yonekawa, Akiko, Inoue, Yoshiaki, Yamagata, Kunihiro, Chiba, Shigeru, Narumoto, Osamu, Nagai, Hideaki, Ooshima, Nobuharu, Motegi, Mitsuru, Sagara, Hironori, Tanaka, Akihiko, Ohta, Shin, Shibata, Yoko, Tanino, Yoshinori, Sato, Yuki, Yamada, Yuichiro, Hashino, Takuya, Shinoki, Masato, Iwagoe, Hajime, Imamura, Tomonori, Umeda, Akira, Shimada, Hisato, Endo, Mayu, Hayashi, Shinichi, Takahashi, Mai, Nakano, Shigefumi, Yatomi, Masakiyo, Maeno, Toshitaka, Ishii, Tomoo, Utsugi, Mitsuyoshi, Ono, Akihiro, Kanaoka, Kensuke, Ihara, Shoichi, Komuta, Kiyoshi, Nishida, Nao, Kawai, Yosuke, Sugiyama, Masaya, Alawneh, Laith M., Maswadeh, Kinda B., Alsoub, Fatima S., AlRawashdeh, Tala J., Esawi, Ezaldeen, Abu Alragheb, Bayan O., Maswadeh, Ahmad B., Al-Kadash, Abdulfattah, Al-Ani, Abdallah, Alsafadi, Dana B., Shahin, Mohammad A., Qtaish, Nuseibah Al, Alawneh, Fade M., Abulail, Joseph A., Zhlawi, Hadi J., Alhousani, Tasneem N., Alzuraiqi, Mohammad R., Al-Ja’afreh, Mohammad M., Allouzy, Sara K., ALjalamdeh, Mothafer, Mansour, Tareq M., Alamer, Lina M., Issa, Ali Banni, Bani younis, Fatima M., Hawari, Feras I., Hayajneh, Wail A., Obeidat, Nathir M., Ahram, Mamoun, Zhlawi, Moh’d Wahib J., Alshaer, Walhan, Al-Kasasbeh, Malak M., Naffa, Randa G., Ismail, Mohammad A., Abdullah, Mohammed S., Ismail, Said I., Obeidat, Ma’en, Hernández Cordero, Ana I., Sin, Don D., Bossé, Yohan, Joubert, Philippe, Hao, Ke, Nickle, David, Timens, Wim, van den Berge, Maarten, Feng, Yen-Chen Anne, Mercader, Josep, Weiss, Scott T., Karlson, Elizabeth W., Smoller, Jordan W., Murphy, Shawn N., Meigs, James B., Woolley, Ann E., Green, Robert C., Mandla, Ravi, Schroeder, Philip, Perez, Emma F., Lee, Seung Hyuk T., Flores-Silva, Fernando Daniel, Chiquete, Erwin, Cantú-Brito, Carlos, Sifuentes-Osornio, José, de León-Garduño, Alfredo Ponce, Román-Montes, Carla Marina, Chávez-Manzanera, Emma, Velasco, Donaji Gómez, Martagón-Rosado, Alexandro, Cruz-Bautista, Ivette, Gómez-Pérez, Francisco Javier, Díaz-Olavarrieta, Claudia, Valdés, Paloma Almeda, Muñóz-Hernández, Linda Liliana, Mehta, Roopa Pravin, Elías-López, Daniel, Tusié-Luna, Teresa, Pajukanta, Päivi, Sukhatme, Mihir G., Moreno-Macías, Hortensia, Ruth, Johnson, González-Behn-Eschenburg, Sebastián, García-Grimshaw, Miguel, Guillen-Pineda, Luz Elizabeth, de los Ángeles Vargas-Martínez, María, Rodríguez, Maribel, Rodríguez-Guillén, Rosario, Ordoñez, María Luisa, Rajme-López, Sandra, González-Lara, María Fernanda, Luna-Moreno, Dalia, de Jesús Suárez López, Jannet, Guillén-Quintero, Daniela Mariel, Vega, Juan, Duran-Coyote, Salvador, Guerra-García, María Teresa, Durán-Gómez, Michelle, Vigueras-Hernández, Alma, Ramírez-Jiménez, Marco Eduardo, Grajeda-González, Samara Lissete, Ramos-Galicia, Enrique Manuel, Ramírez-Carrillo, Martha Fernanda, Fernandez-Ruiz, Juan, Chirino-Pérez, Amanda, Romero-Molina, Ángel Omar, Zavaleta, David Alejandro Fuentes, Jaramillo, María Andrea Mac Donald, López, Katia Jarely Prieto, Incontri-Abraham, Diego, Rosado, Wendy Natalia, Catalán, María Alonso, Aguilar, Sonia Evelyn Vital, Zamudio, Ileana Paola Montero, Ruíz-Ruíz, Eduardo, de Jesús Carrera García, Kevin, Guerrero, Cristina Villarreal, Martínez, Ana Isabel Rodríguez, Moscoso-Sánchez, Rogelio, del Consuelo Rodríguez Mancilla, María, Villa, Antonio, Luna-Ramírez, Samuel Alejandro, Hernández-Hernández, Sergio, Frias, Erika, Campos, Alejandro, Morales-Sosa, Paola Alessandra, Toxqui-Merchant, Luis Enrique, García, Karla, Pasaniuc, Bogdan, Butte, Manish J., Geschwind, Daniel H., Aguilar-Salinas, Carlos A., Heidecker, Bettina, Kurth, Florian, Sander, Leif E., Skurk, Carsten, Landmesser, Ulf, Karadeniz, Zehra, Wang, Xiaomin, Poller, Wolfgang, Suwalski, Phillip, Ripke, Stephan, Braun, Alice, Kraft, Julia, Mayer, Alena, Lippert, Lena J., Helbig, Elisa T., Thibeault, Charlotte, Awasthi, Swapnil, Mbarek, Hamdi, Saad, Chadi, Al-Sarraj, Yaser, Badji, Radja Messai, Al-Muftah, Wadha, Thani, Asma Al, Afifi, Nahla, Sadiq, Fouzia, Khan, Mohammad I., Bhutta, Muhammad J., Khan, Hania, Khan, Madeeha, Ain, Quratul, Junaid, Ayesha, Khan, Ejaz A., Sypniewski, Mateusz, Lejman, Adrian, Zawadzki, Paweł, Sztromwasser, Paweł, Król, Zbigniew, Dobosz, Paula, Stojak, Joanna, Flores, Carlos, Carracedo, Ángel, Aguilar, Carlos, Arranz, María J., Baptista-Rosas, Raúl C., Bezerra, Joao F., Bezerra, Marcos A. C., Brugada, Ramón, Bustos, Matilde, Castano, Luis, Conde-Vicente, Rosa, Cordero-Lorenzana, M. Lourdes, De Martino-Rodríguez, Alba, Domínguez-Garrido, Elena, Fariñas, María Carmen, Gil-Fournier, Belén, Herrero, María José, Lattig, María Claudia, Martín-López, Caridad, Martín, Vicente, Martinez-Nieto, Oscar, Martinez-Lopez, Iciar, Mazzeu, Juliana F., Macías, Eleuterio Merayo, Cuerda, Victor Moreno, Silbiger, Vivian N., Oliveira, Silviene F., Parellada, Mara, Santos, Ney P. C., Pérez-Matute, Patricia, Perez, Patricia, Perucho, Teresa, Porras-Hurtado, Gloria L., Pujol, Aurora, Fernández-Rodríguez, Amanda, Jimenez-Sousa, María A., Rodríguez-Ruiz, Emilio, Rodriguez-Artalejo, Fernando, Rodriguez-Garcia, José A., Ruiz-Cabello, Francisco, Soria, José Manuel, Tamayo, Eduardo, Teper, Alejandro, Torres-Tobar, Lilian, Urioste, Miguel, Yáñez, Zuleima, Zarate, Ruth, Guillen-Navarro, Encarna, Ayuso, Carmen, González-Neira, Anna, Riancho, José A., Rojas-Martinez, Augusto, Lapunzina, Pablo, Cruz, Raquel, Diz-de Almeida, Silvia, Ceballos, Francisco C., Lorenzo-Salazar, José M., González-Montelongo, Rafaela, Quintela, Inés, Pita, Guillermo, Gago-Domínguez, Manuela, Porras, Marta Sevilla, Tenorio-Castaño, Jair Antonio, Nevado, Julian, Aguado, Jose María, Aguilera-Albesa, Sergio, Almadana, Virginia, Almoguera, Berta, Alvarez, Nuria, Andreu-Bernabeu, Álvaro, Arango, Celso, Artiga, Maria-Jesus, Barreda-Sánchez, María, Belhassen-Garcia, Moncef, Boix-Palop, Lucía, Brion, María, Carbonell, Cristina, Castelao, Jose E., Cortes-Sanchez, Jose L., Corton, Marta, Darnaude, M. Teresa, del Campo-Pérez, Victor, de Bustamante, Aranzazu Diaz, Luchessi, Andre D., Eiros, Rocío, Sanabria, Gladys Mercedes Estigarribia, Fernández-Robelo, Uxía, Fernández-Villa, Tania, Gómez-Arrue, Javier, Álvarez, Beatriz González, de Quirós, Fernan Gonzalez Bernaldo, González-Peñas, Javier, Gutiérrez-Bautista, Juan F., Herrero-Gonzalez, Antonio, Borja, Anabel Liger, Lopez-Rodriguez, Rosario, Mancebo, Esther, Martinez-Resendez, Michel F., Martinez-Perez, Angel, Minguez, Pablo, Ortega-Paino, Eva, Paz-Artal, Estela, Pérez-Tomás, M. Elena, Pinsach-Abuin, Mel·lina, Pompa-Mera, Ericka N., León, Soraya Ramiro, Resino, Salvador, Fernandes, Marianne R., Ruiz-Hornillos, Javier, Ryan, Pablo, Souto, Juan Carlos, Tamayo-Velasco, Alvaro, Taracido-Fernandez, Juan Carlos, Valencia-Ramos, Juan, de Heredia, Miguel López, Pedersen, Ole B., Erikstrup, Christian, Ostrowski, Sisse R., Stefansson, Kari, Mikkelsen, Susan, Sørensen, Erik, Burgos, Celia, Andersen, Steffen, Brugdorf, Kristoffer, Hansen, Thomas F., Hjalgrim, Henrik, Jemec, Gregor B., Nyegaard, Mette, Werge, Thomas, Johansson, Pär I., Didriksen, Maria, Schwinn, Michael, Jacobsen, Rikke L., Hindhede, Lotte, Rostgaard, Klaus, Gudbjartsson, Daniel, Stefánsson, Hreinn, Þorsteinsdóttir, Unnur, Nielsen, Kaspar R., Bruun, Mie Topholm, Dinh, Khoa M., Larsen, Margit A. H., Sækmose, Susanne G., Zeberg, Hugo, Nkambul, Lindo, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklos, Tardif, Nicolas, Rooyackers, Olav, Grip, Jonathan, Maricic, Tomislav, Heid, Iris M., Wagner, Ralf, Überla, Klaus, Winkler, Thomas W., Wiegrebe, Simon, Gorski, Mathias, Stark, Klaus J., Peterhoff, David, Einhauser, Sebastian, Niller, Hans-Helmut, Beileke, Stephanie, Johnson, Ruth, Freimer, Nelson, Ding, Yi, Chiu, Alec, Chang, Timothy S., Boutros, Paul, Karczewski, Konrad J., Martin, Alicia R., Wilson, Daniel J., Spencer, Chris C. A., Crook, Derrick W., Wyllie, David H., O’Connell, Anne Marie, Atkinson, Elizabeth G., Tsuo, Kristin, Baya, Nikolas, Turley, Patrick, Gupta, Rahul, Walters, Raymond K., Palmer, Duncan S., Sarma, Gopal, Solomonson, Matthew, Cheng, Nathan, Lu, Wenhan, Churchhouse, Claire, Goldstein, Jacqueline I., King, Daniel, Zhou, Wei, Seed, Cotton, Daly, Mark J., Finucane, Hilary, Bryant, Sam, Satterstrom, F. Kyle, Band, Gavin, Earle, Sarah G., Lin, Shang-Kuan, Arning, Nicolas, Koelling, Nils, Armstrong, Jacob, Rudkin, Justine K., Callier, Shawneequa, Cusick, Caroline, Fernandez-Cadenas, Israel, Planas, Anna M., Perez-Tur, Jordi, Llucià-Carol, Laia, Cullell, Natalia, Muiño, Elena, Cárcel-Márquez, Jara, DeDiego, Marta L., Iglesias, Lara Lloret, Soriano, Alex, Rico, Veronica, Agüero, Daiana, Bedini, Josep L., Lozano, Francisco, Domingo, Carlos, Robles, Veronica, Ruiz-Jaén, Francisca, Márquez, Leonardo, Gomez, Juan, Coto, Eliecer, Albaiceta, Guillermo M., García-Clemente, Marta, Dalmau, David, Arranz, Maria J., Dietl, Beatriz, Serra-Llovich, Alex, Soler-Palacin, Pere, Colobran, Roger, Martin-Nalda, Andrea, Parra-Martínez, Alba, Bernardo, David, Rojo, Silvia, Fiz-López, Aida, Arribas-Rodriguez, Elisa, Cal-Sabater, Paloma, Segura, Tomás, González-Villar, Esther, Serrano-Heras, Gemma, Martí-Fàbregas, Joan, Jiménez-Xarrié, Elena, de Felipe Mimbrera, Alicia, Masjuan, Jaime, García-Madrona, Sebastian, Domínguez-Mayoral, Anna, Villalonga, Joan Montaner, and Menéndez-Valladares, Paloma
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- 2023
16. Salt-affected soils in Tanzanian agricultural lands:Type of soils and extent of the problem
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Omar, M. M., Shitindi, M. J., Massawe, B. H.J., Fue, K. G., Meliyo, J. L., Pedersen, O., Omar, M. M., Shitindi, M. J., Massawe, B. H.J., Fue, K. G., Meliyo, J. L., and Pedersen, O.
- Abstract
Salt-affected soils are a global challenge, affecting 1 billion ha of land, with 200 million ha found in Africa. The challenge brings adverse impacts on agricultural productivity, food security, environmental sustainability, and food security. In Tanzania, more than 2 million ha of land are salt-affected, of which 1.7 million ha are saline soil and 0.3 million ha are sodic soil. To cope with this threat, it is necessary to have a thorough understanding of its extent (coverage), existing types, and available management strategies. This review presents a comprehensive account of the challenges and opportunities of salt-affected soils in Tanzania and examines management options that have been observed to increase agricultural productivity in rice-growing areas. A systematic review of relevant articles published in databases was carried out using PRISMA guidelines and flowcharts. This review highlights the origin, extent, types, and various techniques for alleviating salt-affected soil problems. It also emphasize on the use of inorganic and organic amendments, salt-tolerant varieties, irrigation water quality, and drainage infrastructure. We revealed that farmers, use burned and unburned rice husks, sawdust, gypsum, and farm yard manure (FYM) as copping mechanisms. Furthermore, there have been continuing efforts to develop salt-tolerant rice varieties, coupled with maintenance of irrigation infrastructure and site-specific soil management options, as appropriate solutions to tackle salt issues. Given the light of existing data, the review recommends using RS and GIS for updating information on salt-affected soils, particularly in irrigated areas, as an essential component of sustainable management and preventing further loss of agricultural land., Salt-affected soils are a global challenge, affecting 1 billion ha of land, with 200 million ha found in Africa. The challenge brings adverse impacts on agricultural productivity, food security, environmental sustainability, and food security. In Tanzania, more than 2 million ha of land are salt-affected, of which 1.7 million ha are saline soil and 0.3 million ha are sodic soil. To cope with this threat, it is necessary to have a thorough understanding of its extent (coverage), existing types, and available management strategies. This review presents a comprehensive account of the challenges and opportunities of salt-affected soils in Tanzania and examines management options that have been observed to increase agricultural productivity in rice-growing areas. A systematic review of relevant articles published in databases was carried out using PRISMA guidelines and flowcharts. This review highlights the origin, extent, types, and various techniques for alleviating salt-affected soil problems. It also emphasize on the use of inorganic and organic amendments, salt-tolerant varieties, irrigation water quality, and drainage infrastructure. We revealed that farmers, use burned and unburned rice husks, sawdust, gypsum, and farm yard manure (FYM) as copping mechanisms. Furthermore, there have been continuing efforts to develop salt-tolerant rice varieties, coupled with maintenance of irrigation infrastructure and site-specific soil management options, as appropriate solutions to tackle salt issues. Given the light of existing data, the review recommends using RS and GIS for updating information on salt-affected soils, particularly in irrigated areas, as an essential component of sustainable management and preventing further loss of agricultural land.
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- 2023
17. The differentiating effect of COVID-19-associated stress on the morbidity of blood donors with symptoms of hidradenitis suppurativa, hyperhidrosis, or psoriasis
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Henning, M. A.S., Didriksen, M., Ibler, K. S., Ostrowski, S. R., Erikstrup, C., Nielsen, K., Sækmose, S. G., Hansen, T. F., Ullum, H., Thørner, L. W., Kaspersen, K. A., Mikkelsen, S., Jemec, G. B.E., Pedersen, O. B., Henning, M. A.S., Didriksen, M., Ibler, K. S., Ostrowski, S. R., Erikstrup, C., Nielsen, K., Sækmose, S. G., Hansen, T. F., Ullum, H., Thørner, L. W., Kaspersen, K. A., Mikkelsen, S., Jemec, G. B.E., and Pedersen, O. B.
- Abstract
Purpose: The burden of different skin diseases may vary leading individuals to have different sensitivity to stress. Therefore, we compared the health-related quality of life (HRQoL) and stress before and during the universal stress from the severe acute respiratory syndrome coronavirus-2-pandemic in individuals with and without hyperhidrosis, hidradenitis suppurativa, or psoriasis. Methods: The study cohort was the Danish Blood Donor Study. Overall, 12,798 participants completed a baseline questionnaire before the pandemic, in 2018–2019, and a follow-up questionnaire during the pandemic, in 2020. Regression determined the association between the skin diseases and outcomes. Outcomes were the physical and mental component summary (MCS, PCS, respectively), which assess the mental and physical HRQoL, and the perceived stress scale, which assesses stress in the past four weeks. Results: Overall, 1168 (9.1%) participants had hyperhidrosis, 363 (2.8%) had hidradenitis suppurativa, and 402 (3.1%) had psoriasis. At follow-up, the participants with hyperhidrosis had worse MCS (coefficient −0.59 [95% confidence interval (CI) −1.05, −0.13]) and higher odds of moderate-to-severe stress (odds ratio 1.37 [95% CI 1.13, 1.65]) and the participants with hidradenitis suppurativa worse PCS (coefficient −0.74 [95% CI −1.21, −0.27]) than the control groups. The associations were independent of baseline HRQoL, stress, the Connor-Davidson Resilience scale, and other covariables. Psoriasis was not associated with the outcomes. Conclusion: Individuals with hyperhidrosis or hidradenitis suppurativa experienced worse mental or physical well-being and individuals with hyperhidrosis also had higher stress during the pandemic compared to healthy individuals. This suggests that individuals with these skin diseases are particularly susceptible to external stress.
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- 2023
18. Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials
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Dawed, Adem Y, primary, Mari, Andrea, additional, Brown, Andrew, additional, McDonald, Timothy J, additional, Li, Lin, additional, Wang, Shuaicheng, additional, Hong, Mun-Gwan, additional, Sharma, Sapna, additional, Robertson, Neil R, additional, Mahajan, Anubha, additional, Wang, Xuan, additional, Walker, Mark, additional, Gough, Stephen, additional, Hart, Leen M ‘t, additional, Zhou, Kaixin, additional, Forgie, Ian, additional, Ruetten, Hartmut, additional, Pavo, Imre, additional, Bhatnagar, Pallav, additional, Jones, Angus G, additional, Pearson, Ewan R, additional, 't Hart, L.M., additional, Abdalla, M., additional, Adam, J., additional, Adamski, J., additional, Adragni, K., additional, Allin, K.H., additional, Arumugam, M., additional, Atabaki Pasdar, N., additional, Baltauss, T., additional, Banasik, K.B., additional, Baum, P., additional, Bell, J.D., additional, Bergstrom, M., additional, Beulens, J.W., additional, Bianzano, S., additional, Bizzotto, R., additional, Bonneford, A., additional, Brorsson, C.A.B., additional, Brown, A.A., additional, Brunak, S.B., additional, Cabrelli, L., additional, Caiazzo, R., additional, Canouil, M., additional, Dale, M., additional, Davtian, D., additional, Dawed, A.Y., additional, De Masi, F.M., additional, de Preville, N., additional, Dekkers, K.F., additional, Dermitzakis, E.T., additional, Deshmukh, H.A., additional, Dings, C., additional, Donnelly, L., additional, Dutta, A., additional, Ehrhardt, B., additional, Elders, P.J.M., additional, Engel Thomas, C.E.T., additional, Engelbrechtsen, L., additional, Eriksen, R.G., additional, Eriksen, R.E., additional, Fan, Y., additional, Fernandez, J., additional, Ferrer, J., additional, Fitipaldi, H., additional, Forgie, I.M., additional, Forman, A., additional, Franks, P.W., additional, Frau, F., additional, Fritsche, A., additional, Froguel, P., additional, Frost, G., additional, Gassenhuber, J., additional, Giordano, G.N., additional, Giorgino, T., additional, Gough, S., additional, Graefe-Mody, U., additional, Grallert, H., additional, Grempler, R., additional, Groeneveld, L., additional, Groop, L., additional, Gudmundsdóttir, V.G., additional, Gupta, R.G., additional, Haid, M., additional, Hansen, T., additional, Hansen, T.H., additional, Hattersley, A.T., additional, Haussler, R.S., additional, Heggie, A.J., additional, Hennige, A.M., additional, Hill, A.V., additional, Holl, R.W., additional, Hong, M.-G., additional, Hudson, M., additional, Jablonka, B., additional, Jennison, C., additional, Jiao, J., additional, Johansen, J.J., additional, Jones, A.G., additional, Jonsson, A., additional, Karaderi, T.K., additional, Kaye, J., additional, Klintenberg, M., additional, Koivula, R.W., additional, Kokkola, T., additional, Koopman, A.D.M., additional, Kurbasic, A, additional, Kuulasmaa, T., additional, Laakso, M., additional, Lehr, T., additional, Loftus, H., additional, Lundbye Allesøe, R.L.A, additional, Mahajan, A., additional, Mari, A., additional, Mazzoni, G.M., additional, McCarthy, M.I., additional, McDonald, T.J., additional, McEvoy, D., additional, McRobert, N., additional, McVittie, I., additional, Mourby, M., additional, Musholt, P., additional, Mutie, P, additional, Nice, R., additional, Nicolay, C., additional, Nielsen, A.M.N., additional, Nilsson, B.N., additional, Palmer, C.N., additional, Pattou, F., additional, Pavo, I., additional, Pearson, E.R., additional, Pedersen, O., additional, Pedersen, H.K.P., additional, Perry, M.H., additional, Pomares-Millan, H., additional, Ramisch, A., additional, Rasmussen, S.R., additional, Raverdi, V., additional, Ridderstrale, M., additional, Robertson, N., additional, Roderick, R.C., additional, Rodriquez, M., additional, Ruetten, H., additional, Rutters, F., additional, Sackett, W., additional, Scherer, N., additional, Schwenk, J.M., additional, Shah, N., additional, Sharma, S., additional, Sihinevich, I., additional, Sondertoft, N.B., additional, Staerfeldt, H., additional, Steckel-Hamann, B., additional, Teare, H., additional, Thomas, M.K., additional, Thomas, E.L., additional, Thomsen, H.S., additional, Thorand, B., additional, Thorne, C.E., additional, Tillner, J., additional, Troen Lundgaard, A.T.L., additional, Troll, M., additional, Tsirigos, K.D.T., additional, Tura, A., additional, Uhlen, M., additional, van Leeuwen, N., additional, van Oort, S., additional, Verkindt, H., additional, Vestergaard, H., additional, Viñuela, A., additional, Vogt, J.K, additional, Wad Sackett, P.W.S, additional, Wake, D., additional, Walker, M., additional, Wesolowska-Andersen, A., additional, Whitcher, B., additional, White, M.W., additional, and Wu, H., additional
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- 2023
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19. Turf algal epiphytes metabolically induce local pH increase, with implications for underlying coralline algae under ocean acidification
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Short, J.A., Pedersen, O., and Kendrick, G.A.
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- 2015
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20. Vejle Diabetes Biobank – a resource for studies of the etiologies of diabetes and its comorbidities
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Petersen ERB, Nielsen AA, Christensen H, Hansen T, Pedersen O, Christensen CK, and Brandslund I
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Diabetes ,type 2 diabetes ,HbA1c ,diabetes Biobank resource ,research database ,Infectious and parasitic diseases ,RC109-216 - Abstract
Eva Rabing Brix Petersen,1,2 Aneta Aleksandra Nielsen,1 Henry Christensen,1 Torben Hansen,3 Oluf Pedersen,3 Cramer Kjeldahl Christensen,4 Ivan Brandslund1,2 1Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, 2Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, 3Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 4Department of Internal Medicine and Endocrinology, Lillebaelt Hospital, Vejle, Denmark Aims: Carefully designed and established biobanks are considered one of the most essential resources to foster biomedical research as they provide cost-effective and rapid access to a vast variety of biological materials and related anthropometrics allowing for testing of various biomarkers as well as numerous original and pertinent bioclinical hypotheses related to human disease etiology and prognosis. The objective of the present study was to present the baseline data, design, and methods used for the establishment of the Vejle Diabetes Biobank. Further aims included assessment of the prevalence of diabetes and quality of diabetes treatment in a specified Danish region.Methods: The Vejle Diabetes Biobank was established from 2007 to 2010 as a regional Biobank containing blood, DNA, and urine samples from patients with diabetes and a gender- and age-matched control population aged 25–75 years. Anthropometrics were obtained by physical examination, questionnaires, and interviews at the time of inclusion into the Biobank. The cohort was linked to the Danish Civil Registration System, the Danish National Patient Registry, and the Danish National Prescription Registry.Results: In total, 4,255 nondiabetic individuals and 3,320 patients with diabetes were included. Type 2 diabetes (T2D) patients had a higher body mass index (30 kg/m2) than type 1 diabetes (T1D) patients (25 and 26 kg/m2 in women and men, respectively) and control subjects (25 and 27 kg/m2 in women and men, respectively). Fasting levels of plasma triglycerides and blood pressure were higher in T2D patients (1.5 mmol/L and 148/85 mmHg, respectively) compared with T1D patients (0.9 mmol/L and 139/81 mmHg, respectively), whereas glycated hemoglobin (HbA1c), plasma high density lipoprotein, low density lipoprotein, and total cholesterol were lower in T2D patients (51 mmol/mol, 1.2 mmol/L, 2.2 mmol/L, and 4.2 mmol/L, respectively) compared with findings in T1D patients (61 mmol/mol, 1.6 mmol/L, 2.3 mmol/L, and 4.4 mmol/L, respectively). At the time of inclusion into the Biobank, 56% of the T2D patients and 25% of T1D patients had an HbA1c
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- 2016
21. Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies
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Møllehave, L T, Skaaby, T, Simonsen, K S, Thuesen, B H, Mortensen, E L, Sandholt, C H, Pedersen, O, Grarup, N., Hansen, T., and Linneberg, A.
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Folic acid -- Genetic aspects -- Health aspects -- Psychological aspects ,Depression, Mental -- Genetic aspects -- Risk factors ,Vitamin B12 -- Genetic aspects -- Health aspects -- Psychological aspects ,Anxiety -- Genetic aspects -- Risk factors ,Food/cooking/nutrition ,Health - Abstract
Background/Objectives: Observational studies have suggested low serum levels of vitamin B12 or folate to be risk factors of depression and anxiety. However, these results may be biased by confounding and reverse causation. Mendelian randomization studies are not subject to these limitations. The aim was to examine the association of genetic scores of vitamin B12 and folate-associated alleles with depression and anxiety. Subjects/Methods: The study included 4126 participants from two Danish population-based studies. Serum vitamin B12 and folate were measured. Weighed allele scores were calculated as the sum of weights (genetic effect sizes) for 12 and two variants increasing circulating levels of vitamin B12 and folate, respectively. Symptoms of depression and anxiety were assessed by the Symptom Check List (SCL)-90-R, and self-reported doctor-diagnosed depression and anxiety. Results: An increased weighed allele score for serum vitamin B12 was associated with decreased odds of a SCL-90-R score above the 90th percentile (OR 0.540 (95%CI 0.302-0.967)) in Health2006 but not in Inter99, in the pooled analysis (OR 0.817 (95%CI 0.331-2.018)) or with other outcomes. The weighed allele score for serum folate was not associated with any of the measured outcome variables: SCL-90-R scores of depression (pooled OR 0.603 (95%CI 0.101-3.602)), anxiety (pooled OR 0.619 (95%CI 0.110-3.495)), combined score or history of doctor-diagnosed depression or anxiety. Conclusion: Our results do not provide evidence for a causal effect of circulating folate or vitamin B12 on the risk of depression or anxiety. However, we cannot rule out small to moderate effects, and thus large scale studies are needed., Author(s): L T Møllehave [sup.1] , T Skaaby [sup.1] , K S Simonsen [sup.1] , B H Thuesen [sup.1] , E L Mortensen [sup.2] [sup.3] , C H Sandholt [sup.4] [...]
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- 2017
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22. Exploring farmers’ perception, knowledge, and management techniques of salt-affected soils to enhance rice production on small land holdings in Tanzania
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Omar, M. M, primary, Shitindi, M. J., additional, Massawe, B. H. J, additional, Fue, K. G, additional, Pedersen, O., additional, and Meliyo, J. L., additional
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- 2022
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23. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
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Wesolowska-Andersen A, Brorsson CA, Bizzotto R, Mari A, Tura A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Prehn C, Artati A, Hong MG, Musholt PB, Kurbasic A, De Masi F, Tsirigos K, Pedersen HK, Gudmundsdottir V, Thomas CE, Banasik K, Jennison C, Jones A, Kennedy G, Bell J, Thomas L, Frost G, Thomsen H, Allin K, Hansen TH, Vestergaard H, Hansen T, Rutters F, Elders P, t'Hart L, Bonnefond A, Canouil M, Brage S, Kokkola T, Heggie A, McEvoy D, Hattersley A, McDonald T, Teare H, Ridderstrale M, Walker M, Forgie I, Giordano GN, Froguel P, Pavo I, Ruetten H, Pedersen O, Dermitzakis E, Franks PW, Schwenk JM, Adamski J, Pearson E, McCarthy MI, Brunak S, and ID Consortium
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General Economics, Econometrics and Finance - Published
- 2022
24. The impact of age on the 99th percentile of cardiac troponin
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Hasselbalch, R, primary, Strandkjaer, N, additional, Kristensen, J, additional, Joergensen, N, additional, Kock, T O, additional, Rye Ostrowski, S, additional, Vesterager Pedersen, O B, additional, Torp-Pedersen, C, additional, Bundgaard, H, additional, Bor, V, additional, Afzal, S, additional, Kamstrup, P, additional, Dahl, M, additional, Hilsted, L, additional, and Iversen, K I, additional
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- 2022
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25. Hypersalinity effects on O2 flux across the diffusive boundary layer of leaves in the tropical seagrass Thalassia testudinum
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Koch, M.S., primary, Johnson, C.R., additional, Travis, L., additional, Pedersen, O., additional, and Madden, C.J., additional
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- 2022
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26. Low irradiance disrupts the internal O2 dynamics of seagrass (Thalassia testudinum) leading to shoot meristem H2S intrusion
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Koch, M.S., primary, Johnson, C.R., additional, Madden, C.J., additional, and Pedersen, O., additional
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- 2022
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27. Role of a groundwater–lake interface in controlling seepage of water and nitrate
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Karan, S., Kidmose, J., Engesgaard, P., Nilsson, B., Frandsen, M., Ommen, D.A.O., Flindt, M.R., Andersen, F.Ø., and Pedersen, O.
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- 2014
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28. Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization
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Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, T., Pedersen, O., Jørgensen, T., Paternoster, L., Munafò, M., Grarup, N., and Linneberg, A.
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- 2018
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29. Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies
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Husemoen, L.L.N., Skaaby, T., Thuesen, B.H., Grarup, N., Sandholt, C.H., Hansen, T., Pedersen, O., and Linneberg, A.
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Vitamin B12 -- Genetic aspects -- Health aspects ,Lipid metabolism -- Genetic aspects -- Health aspects ,Blood pressure -- Genetic aspects -- Health aspects ,Gene expression -- Observations ,Food/cooking/nutrition ,Health - Abstract
BACKGROUND/OBJECTIVES: The aim was to examine the association of genetic risk scores (GRSs) of vitamin B12 and folate-associated variants with blood pressure and lipids. SUBJECTS/METHODS: The study included 12 532 adults from three population-based studies (Inter99, Health2006 and Dan-MONICA10) conducted in Denmark. GRSs were calculated by summarising the number of vitamin B12 and folate increasing alleles. Weighted GRSs were calculated as the sum of weights for each allele corresponding to genetic effects sizes. RESULTS: GRSs for serum vitamin B12 and folate were associated with serum vitamin B12 and folate, respectively. The [beta] coefficients (95% confidence interval (CI), P-value) for regression of log-transformed serum B12/folate on the weighted GRSs were 0.57 (0.54, 0.61), P < 0.001 and 0.85 (0.70, 1.01), P < 0.01. No associations were observed between the vitamin B12 GRSs and any of the blood pressure and lipid-related outcomes in the combined analyses. Increasing number of folate increasing alleles was associated with increased high-density lipoprotein (HDL) cholesterol concentrations ([beta] coefficient (95% CI, P-value) for regression of log-transformed HDL on the weighted GRSs, 0.081 (0.015, 0.148), P = 0.017), but not with blood pressure, triglyceride, and low-density lipoprotein and total cholesterol levels. CONCLUSIONS: GRSs were not associated with blood pressure and lipid levels, except for an association between the GRS for folate and HDL cholesterol. Further studies are needed to determine whether a causal association between folate and HDL cholesterol exists. European Journal of Clinical Nutrition (2016) 70, 613-619; doi: 10.1038/ejcn.2016.5; published online 24 February 2016, INTRODUCTION Despite a large number of epidemiological studies and randomised trials, there is still substantial controversy whether primary intervention with folic acid and vitamin B12 will lower cardiovascular disease (CVD) [...]
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- 2016
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30. AB0006 ESTABLISHED RISK LOCI FOR SYSTEMIC LUPUS ERYTHEMATOSUS AT NCF2, STAT4, TNPO3, IRF5 AND ITGAM ASSOCIATE WITH DISTINCT CLINICAL MANIFESTATIONS: A DANISH GENOME-WIDE ASSOCIATION STUDY
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Leffers, H., primary, Westergaard, D., additional, Saevarsdottir, S., additional, Jonsdottir, I., additional, Pedersen, O. B., additional, Troldborg, A., additional, Voss, A., additional, Kristensen, S., additional, Lindhardsen, J., additional, Kumar, P., additional, Linauskas, A., additional, Juul, L., additional, Steen Krogh, N., additional, Deleuran, B., additional, Dreyer, L., additional, Schwinn, M., additional, Thørner, L. W., additional, Hindhede, L., additional, Erikstrup, C., additional, Ullum, H., additional, Brunak, S., additional, Stefansson, K., additional, Banasik, K., additional, and Jacobsen, S., additional
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- 2022
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31. Cross Slip Viewed at the Nano- and Micrometer Scale
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Leffers, T., Pedersen, O. B., Gladwell, G. M. L., editor, Ahzi, S., editor, Cherkaoui, M., editor, Khaleel, M. A., editor, Zbib, H. M., editor, Zikry, M. A., editor, and Lamatina, B., editor
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- 2004
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32. Airway Geometry Determined by Acoustic Reflections
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Pedersen, O. F., Aliverti, Andrea, editor, Brusasco, Vito, editor, Macklem, Peter T., editor, and Pedotti, Antonio, editor
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- 2002
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33. Leading trait dimensions in flood-tolerant plants
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Pan, Y., Cieraad, E., Armstrong, J., Armstrong, W., Clarkson, B., Pedersen, O., Visser, E.J.W., Voesenek, L.A.C.J., Bodegom, P.M. Van, Pan, Y., Cieraad, E., Armstrong, J., Armstrong, W., Clarkson, B., Pedersen, O., Visser, E.J.W., Voesenek, L.A.C.J., and Bodegom, P.M. Van
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Contains fulltext : 282682.pdf (Publisher’s version ) (Open Access)
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- 2022
34. Incidence and remission rates of self-reported hidradenitis suppurativa - A prospective cohort study conducted in Danish blood donors
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Andersen, R. Kjærsgaard, Loft, I. C., Hansen, T., Hjalgrim, H., Rostgaard, K., Banasik, K., Bruun, M., Nielsen, K., Dinh, K. M., Sørensen, E., Burgdorff, K., Erikstrup, C., Ullum, H., Saunte, D. M., Pedersen, O. B., Jemec, G. B. E., Andersen, R. Kjærsgaard, Loft, I. C., Hansen, T., Hjalgrim, H., Rostgaard, K., Banasik, K., Bruun, M., Nielsen, K., Dinh, K. M., Sørensen, E., Burgdorff, K., Erikstrup, C., Ullum, H., Saunte, D. M., Pedersen, O. B., and Jemec, G. B. E.
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Background A large discrepancy between physician-diagnosed and self-reported Hidradenitis suppurativa (HS) exists. Knowledge regarding incidence and remission rates of self-reported HS is missing, but may help bridge the gap in understanding between these two phenotypes. Objectives To determine the incidence and remission rates of self-reported HS, and to what degree these are affected by sex, smoking and BMI. Methods A prospective cohort of 23 930 Danish blood donors. Information on self-reported HS, symptom-localisation, sex, age, BMI and smoking status was collected at baseline and study termination. Self-reported HS fulfilled clinical obligatory diagnostic criteria. Cox proportional hazards regression analyses were conducted for both incidence and remission rates providing a hazard ratio (HR) of risk for each variable in the regression. Results Incidence rate of self-reported HS was 10.8/1000 person-years (95% confidence interval (CI): 9.9–11.7), decreasing as a function of numbers of areas affected. Female BMI points above 25 (HR = 1.11, 95% CI: 1.09–1.13), male BMI points above 25 (HR = 1.07, 95% CI: 1.04–1.11), active smoking (HR = 1.72, 95% CI: 1.15–2.57), male sex (HR = 0.55, 95% CI: 0.45–0.67) and years of age above 25 (HR = 0.97, 95% CI: 0.96–0.97) were all statistically associated with the development of self-reported HS. Remission rate of self-reported HS was 256.7/1000 person-years (95% CI: 223.9–292.6), decreasing as a function of numbers of affected areas. Symptoms in ≥3 areas (HR = 0.54, 95% CI: 0.34–0.85), active smoking (HR = 0.49, 95% CI: 0.32–0.76) and female weight loss (every percentage drop in BMI: HR = 1.07, 95% CI: 1.05–1.11) all significantly affected the remission rate. Conclusions Both incidence and remission rates of self-reported HS are high, indicating that many with self-reported HS are unlikely to be diagnosed, as they to a higher degree experience mild transient HS symptoms.
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- 2022
35. A saturated map of common genetic variants associated with human height
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Yengo, L, Vedantam, S, Marouli, E, Sidorenko, J, Bartell, E, Sakaue, S, Graff, M, Eliasen, AU, Jiang, Y, Raghavan, S, Miao, J, Arias, JD, Graham, SE, Mukamel, RE, Spracklen, CN, Yin, X, Chen, S-H, Ferreira, T, Highland, HH, Ji, Y, Karaderi, T, Lin, K, Lull, K, Malden, DE, Medina-Gomez, C, Machado, M, Moore, A, Rueger, S, Sim, X, Vrieze, S, Ahluwalia, TS, Akiyama, M, Allison, MA, Alvarez, M, Andersen, MK, Ani, A, Appadurai, V, Arbeeva, L, Bhaskar, S, Bielak, LF, Bollepalli, S, Bonnycastle, LL, Bork-Jensen, J, Bradfield, JP, Bradford, Y, Braund, PS, Brody, JA, Burgdorf, KS, Cade, BE, Cai, H, Cai, Q, Campbell, A, Canadas-Garre, M, Catamo, E, Chai, J-F, Chai, X, Chang, L-C, Chang, Y-C, Chen, C-H, Chesi, A, Choi, SH, Chung, R-H, Cocca, M, Concas, MP, Couture, C, Cuellar-Partida, G, Danning, R, Daw, EW, Degenhard, F, Delgado, GE, Delitala, A, Demirkan, A, Deng, X, Devineni, P, Dietl, A, Dimitriou, M, Dimitrov, L, Dorajoo, R, Ekici, AB, Engmann, JE, Fairhurst-Hunter, Z, Farmaki, A-E, Faul, JD, Fernandez-Lopez, J-C, Forer, L, Francescatto, M, Freitag-Wolf, S, Fuchsberger, C, Galesloot, TE, Gao, Y, Gao, Z, Geller, F, Giannakopoulou, O, Giulianini, F, Gjesing, AP, Goel, A, Gordon, SD, Gorski, M, Grove, J, Guo, X, Gustafsson, S, Haessler, J, Hansen, TF, Havulinna, AS, Haworth, SJ, He, J, Heard-Costa, N, Hebbar, P, Hindy, G, Ho, Y-LA, Hofer, E, Holliday, E, Horn, K, Hornsby, WE, Hottenga, J-J, Huang, H, Huang, J, Huerta-Chagoya, A, Huffman, JE, Hung, Y-J, Huo, S, Hwang, MY, Iha, H, Ikeda, DD, Isono, M, Jackson, AU, Jager, S, Jansen, IE, Johansson, I, Jonas, JB, Jonsson, A, Jorgensen, T, Kalafati, I-P, Kanai, M, Kanoni, S, Karhus, LL, Kasturiratne, A, Katsuya, T, Kawaguchi, T, Kember, RL, Kentistou, KA, Kim, H-N, Kim, YJ, Kleber, ME, Knol, MJ, Kurbasic, A, Lauzon, M, Le, P, Lea, R, Lee, J-Y, Leonard, HL, Li, SA, Li, X, Liang, J, Lin, H, Lin, S-Y, Liu, J, Liu, X, Lo, KS, Long, J, Lores-Motta, L, Luan, J, Lyssenko, V, Lyytikainen, L-P, Mahajan, A, Mamakou, V, Mangino, M, Manichaikul, A, Marten, J, Mattheisen, M, Mavarani, L, McDaid, AF, Meidtner, K, Melendez, TL, Mercader, JM, Milaneschi, Y, Miller, JE, Millwood, IY, Mishra, PP, Mitchell, RE, Mollehave, LT, Morgan, A, Mucha, S, Munz, M, Nakatochi, M, Nelson, CP, Nethander, M, Nho, CW, Nielsen, AA, Nolte, IM, Nongmaithem, SS, Noordam, R, Ntalla, I, Nutile, T, Pandit, A, Christofidou, P, Parna, K, Pauper, M, Petersen, ERB, Petersen, L, Pitkanen, N, Polasek, O, Poveda, A, Preuss, MH, Pyarajan, S, Raffield, LM, Rakugi, H, Ramirez, J, Rasheed, A, Raven, D, Rayner, NW, Riveros, C, Rohde, R, Ruggiero, D, Ruotsalainen, SE, Ryan, KA, Sabater-Lleal, M, Saxena, R, Scholz, M, Sendamarai, A, Shen, B, Shi, J, Shin, JH, Sidore, C, Sitlani, CM, Slieker, RKC, Smit, RAJ, Smith, A, Smith, JA, Smyth, LJ, Southam, LE, Steinthorsdottir, V, Sun, L, Takeuchi, F, Tallapragada, D, Taylor, KD, Tayo, BO, Tcheandjieu, C, Terzikhan, N, Tesolin, P, Teumer, A, Theusch, E, Thompson, DJ, Thorleifsson, G, Timmers, PRHJ, Trompet, S, Turman, C, Vaccargiu, S, van der Laan, SW, van der Most, PJ, van Klinken, JB, van Setten, J, Verma, SS, Verweij, N, Veturi, Y, Wang, CA, Wang, C, Wang, L, Wang, Z, Warren, HR, Wei, WB, Wickremasinghe, AR, Wielscher, M, Wiggins, KL, Winsvold, BS, Wong, A, Wu, Y, Wuttke, M, Xia, R, Xie, T, Yamamoto, K, Yang, J, Yao, J, Young, H, Yousri, NA, Yu, L, Zeng, L, Zhang, W, Zhang, X, Zhao, J-H, Zhao, W, Zhou, W, Zimmermann, ME, Zoledziewska, M, Adair, LS, Adams, HHH, Aguilar-Salinas, CA, Al-Mulla, F, Arnett, DK, Asselbergs, FW, Asvold, BO, Attia, J, Banas, B, Bandinelli, S, Bennett, DA, Bergler, T, Bharadwaj, D, Biino, G, Bisgaard, H, Boerwinkle, E, Boger, CA, Bonnelykke, K, Boomsma, D, Borglum, AD, Borja, JB, Bouchard, C, Bowden, DW, Brandslund, I, Brumpton, B, Buring, JE, Caulfield, MJ, Chambers, JC, Chandak, GR, Chanock, SJ, Chaturvedi, N, Chen, Y-DI, Chen, Z, Cheng, C-Y, Christophersen, IE, Ciullo, M, Cole, JW, Collins, FS, Cooper, RS, Cruz, M, Cucca, F, Cupples, LA, Cutler, MJ, Damrauer, SM, Dantoft, TM, de Borst, GJ, de Groot, LCPGM, De Jager, PL, de Kleijn, DP, de Silva, HJ, Dedoussis, G, den Hollander, A, Du, S, Easton, DF, Elders, PJM, Eliassen, AH, Ellinor, PT, Elmstahl, S, Erdmann, J, Evans, MK, Fatkin, D, Feenstra, B, Feitosa, MF, Ferrucci, L, Ford, I, Fornage, M, Franke, A, Franks, PW, Freedman, B, Gasparini, P, Gieger, C, Girotto, G, Goddard, ME, Golightly, YM, Gonzalez-Villalpando, C, Gordon-Larsen, P, Grallert, H, Grant, SFA, Grarup, N, Griffiths, L, Gudnason, V, Haiman, C, Hakonarson, H, Hansen, T, Hartman, CA, Hattersley, AT, Hayward, C, Heckbert, SR, Heng, C-K, Hengstenberg, C, Hewitt, AW, Hishigaki, H, Hoyng, CB, Huang, PL, Huang, W, Hunt, SC, Hveem, K, Hypponen, E, Iacono, WG, Ichihara, S, Ikram, MA, Isasi, CR, Jackson, RD, Jarvelin, M-R, Jin, Z-B, Jockel, K-H, Joshi, PK, Jousilahti, P, Jukema, JW, Kahonen, M, Kamatani, Y, Kang, KD, Kaprio, J, Kardia, SLR, Karpe, F, Kato, N, Kee, F, Kessler, T, Khera, A, Khor, CC, Kiemeney, LALM, Kim, B-J, Kim, EK, Kim, H-L, Kirchhof, P, Kivimaki, M, Koh, W-P, Koistinen, HA, Kolovou, GD, Kooner, JS, Kooperberg, C, Kottgen, A, Kovacs, P, Kraaijeveld, A, Kraft, P, Krauss, RM, Kumari, M, Kutalik, Z, Laakso, M, Lange, LA, Langenberg, C, Launer, LJ, Le Marchand, L, Lee, H, Lee, NR, Lehtimaki, T, Li, H, Li, L, Lieb, W, Lin, X, Lind, L, Linneberg, A, Liu, C-T, Loeffler, M, London, B, Lubitz, SA, Lye, SJ, Mackey, DA, Magi, R, Magnusson, PKE, Marcus, GM, Vidal, PM, Martin, NG, Marz, W, Matsuda, F, McGarrah, RW, McGue, M, McKnight, AJ, Medland, SE, Mellstrom, D, Metspalu, A, Mitchell, BD, Mitchell, P, Mook-Kanamori, DO, Morris, AD, Mucci, LA, Munroe, PB, Nalls, MA, Nazarian, S, Nelson, AE, Neville, MJ, Newton-Cheh, C, Nielsen, CS, Nothen, MM, Ohlsson, C, Oldehinkel, AJ, Orozco, L, Pahkala, K, Pajukanta, P, Palmer, CNA, Parra, EJ, Pattaro, C, Pedersen, O, Pennell, CE, Penninx, BWJH, Perusse, L, Peters, A, Peyser, PA, Porteous, DJ, Posthuma, D, Power, C, Pramstaller, PP, Province, MA, Qi, Q, Qu, J, Rader, DJ, Raitakari, OT, Ralhan, S, Rallidis, LS, Rao, DC, Redline, S, Reilly, DF, Reiner, AP, Rhee, SY, Ridker, PM, Rienstra, M, Ripatti, S, Ritchie, MD, Roden, DM, Rosendaal, FR, Rotter, J, Rudan, I, Rutters, F, Sabanayagam, C, Saleheen, D, Salomaa, V, Samani, NJ, Sanghera, DK, Sattar, N, Schmidt, B, Schmidt, H, Schmidt, R, Schulze, MB, Schunkert, H, Scott, LJ, Scott, RJ, Sever, P, Shiroma, EJ, Shoemaker, MB, Shu, X-O, Simonsick, EM, Sims, M, Singh, JR, Singleton, AB, Sinner, MF, Smith, JG, Snieder, H, Spector, TD, Stampfer, MJ, Stark, KJ, Strachan, DP, t' Hart, LM, Tabara, Y, Tang, H, Tardif, J-C, Thanaraj, TA, Timpson, NJ, Tonjes, A, Tremblay, A, Tuomi, T, Tuomilehto, J, Tusie-Luna, M-T, Uitterlinden, AG, van Dam, RM, van der Harst, P, Van der Velde, N, van Duijn, CM, van Schoor, NM, Vitart, V, Volker, U, Vollenweider, P, Volzke, H, Wacher-Rodarte, NH, Walker, M, Wang, YX, Wareham, NJ, Watanabe, RM, Watkins, H, Weir, DR, Werge, TM, Widen, E, Wilkens, LR, Willemsen, G, Willett, WC, Wilson, JF, Wong, T-Y, Woo, J-T, Wright, AF, Wu, J-Y, Xu, H, Yajnik, CS, Yokota, M, Yuan, J-M, Zeggini, E, Zemel, BS, Zheng, W, Zhu, X, Zmuda, JM, Zonderman, AB, Zwart, J-A, Chasman, D, Cho, YS, Heid, IM, McCarthy, M, Ng, MCY, O'Donnell, CJ, Rivadeneira, F, Thorsteinsdottir, U, Sun, Y, Tai, ES, Boehnke, M, Deloukas, P, Justice, AE, Lindgren, CM, Loos, RJF, Mohlke, KL, North, KE, Stefansson, K, Walters, RG, Winkler, TW, Young, KL, Loh, P-R, Esko, T, Assimes, TL, Auton, A, Abecasis, GR, Willer, CJ, Locke, AE, Berndt, S, Lettre, G, Frayling, TM, Okada, Y, Wood, AR, Visscher, PM, Hirschhorn, JN, Yengo, L, Vedantam, S, Marouli, E, Sidorenko, J, Bartell, E, Sakaue, S, Graff, M, Eliasen, AU, Jiang, Y, Raghavan, S, Miao, J, Arias, JD, Graham, SE, Mukamel, RE, Spracklen, CN, Yin, X, Chen, S-H, Ferreira, T, Highland, HH, Ji, Y, Karaderi, T, Lin, K, Lull, K, Malden, DE, Medina-Gomez, C, Machado, M, Moore, A, Rueger, S, Sim, X, Vrieze, S, Ahluwalia, TS, Akiyama, M, Allison, MA, Alvarez, M, Andersen, MK, Ani, A, Appadurai, V, Arbeeva, L, Bhaskar, S, Bielak, LF, Bollepalli, S, Bonnycastle, LL, Bork-Jensen, J, Bradfield, JP, Bradford, Y, Braund, PS, Brody, JA, Burgdorf, KS, Cade, BE, Cai, H, Cai, Q, Campbell, A, Canadas-Garre, M, Catamo, E, Chai, J-F, Chai, X, Chang, L-C, Chang, Y-C, Chen, C-H, Chesi, A, Choi, SH, Chung, R-H, Cocca, M, Concas, MP, Couture, C, Cuellar-Partida, G, Danning, R, Daw, EW, Degenhard, F, Delgado, GE, Delitala, A, Demirkan, A, Deng, X, Devineni, P, Dietl, A, Dimitriou, M, Dimitrov, L, Dorajoo, R, Ekici, AB, Engmann, JE, Fairhurst-Hunter, Z, Farmaki, A-E, Faul, JD, Fernandez-Lopez, J-C, Forer, L, Francescatto, M, Freitag-Wolf, S, Fuchsberger, C, Galesloot, TE, Gao, Y, Gao, Z, Geller, F, Giannakopoulou, O, Giulianini, F, Gjesing, AP, Goel, A, Gordon, SD, Gorski, M, Grove, J, Guo, X, Gustafsson, S, Haessler, J, Hansen, TF, Havulinna, AS, Haworth, SJ, He, J, Heard-Costa, N, Hebbar, P, Hindy, G, Ho, Y-LA, Hofer, E, Holliday, E, Horn, K, Hornsby, WE, Hottenga, J-J, Huang, H, Huang, J, Huerta-Chagoya, A, Huffman, JE, Hung, Y-J, Huo, S, Hwang, MY, Iha, H, Ikeda, DD, Isono, M, Jackson, AU, Jager, S, Jansen, IE, Johansson, I, Jonas, JB, Jonsson, A, Jorgensen, T, Kalafati, I-P, Kanai, M, Kanoni, S, Karhus, LL, Kasturiratne, A, Katsuya, T, Kawaguchi, T, Kember, RL, Kentistou, KA, Kim, H-N, Kim, YJ, Kleber, ME, Knol, MJ, Kurbasic, A, Lauzon, M, Le, P, Lea, R, Lee, J-Y, Leonard, HL, Li, SA, Li, X, Liang, J, Lin, H, Lin, S-Y, Liu, J, Liu, X, Lo, KS, Long, J, Lores-Motta, L, Luan, J, Lyssenko, V, Lyytikainen, L-P, Mahajan, A, Mamakou, V, Mangino, M, Manichaikul, A, Marten, J, Mattheisen, M, Mavarani, L, McDaid, AF, Meidtner, K, Melendez, TL, Mercader, JM, Milaneschi, Y, Miller, JE, Millwood, IY, Mishra, PP, Mitchell, RE, Mollehave, LT, Morgan, A, Mucha, S, Munz, M, Nakatochi, M, Nelson, CP, Nethander, M, Nho, CW, Nielsen, AA, Nolte, IM, Nongmaithem, SS, Noordam, R, Ntalla, I, Nutile, T, Pandit, A, Christofidou, P, Parna, K, Pauper, M, Petersen, ERB, Petersen, L, Pitkanen, N, Polasek, O, Poveda, A, Preuss, MH, Pyarajan, S, Raffield, LM, Rakugi, H, Ramirez, J, Rasheed, A, Raven, D, Rayner, NW, Riveros, C, Rohde, R, Ruggiero, D, Ruotsalainen, SE, Ryan, KA, Sabater-Lleal, M, Saxena, R, Scholz, M, Sendamarai, A, Shen, B, Shi, J, Shin, JH, Sidore, C, Sitlani, CM, Slieker, RKC, Smit, RAJ, Smith, A, Smith, JA, Smyth, LJ, Southam, LE, Steinthorsdottir, V, Sun, L, Takeuchi, F, Tallapragada, D, Taylor, KD, Tayo, BO, Tcheandjieu, C, Terzikhan, N, Tesolin, P, Teumer, A, Theusch, E, Thompson, DJ, Thorleifsson, G, Timmers, PRHJ, Trompet, S, Turman, C, Vaccargiu, S, van der Laan, SW, van der Most, PJ, van Klinken, JB, van Setten, J, Verma, SS, Verweij, N, Veturi, Y, Wang, CA, Wang, C, Wang, L, Wang, Z, Warren, HR, Wei, WB, Wickremasinghe, AR, Wielscher, M, Wiggins, KL, Winsvold, BS, Wong, A, Wu, Y, Wuttke, M, Xia, R, Xie, T, Yamamoto, K, Yang, J, Yao, J, Young, H, Yousri, NA, Yu, L, Zeng, L, Zhang, W, Zhang, X, Zhao, J-H, Zhao, W, Zhou, W, Zimmermann, ME, Zoledziewska, M, Adair, LS, Adams, HHH, Aguilar-Salinas, CA, Al-Mulla, F, Arnett, DK, Asselbergs, FW, Asvold, BO, Attia, J, Banas, B, Bandinelli, S, Bennett, DA, Bergler, T, Bharadwaj, D, Biino, G, Bisgaard, H, Boerwinkle, E, Boger, CA, Bonnelykke, K, Boomsma, D, Borglum, AD, Borja, JB, Bouchard, C, Bowden, DW, Brandslund, I, Brumpton, B, Buring, JE, Caulfield, MJ, Chambers, JC, Chandak, GR, Chanock, SJ, Chaturvedi, N, Chen, Y-DI, Chen, Z, Cheng, C-Y, Christophersen, IE, Ciullo, M, Cole, JW, Collins, FS, Cooper, RS, Cruz, M, Cucca, F, Cupples, LA, Cutler, MJ, Damrauer, SM, Dantoft, TM, de Borst, GJ, de Groot, LCPGM, De Jager, PL, de Kleijn, DP, de Silva, HJ, Dedoussis, G, den Hollander, A, Du, S, Easton, DF, Elders, PJM, Eliassen, AH, Ellinor, PT, Elmstahl, S, Erdmann, J, Evans, MK, Fatkin, D, Feenstra, B, Feitosa, MF, Ferrucci, L, Ford, I, Fornage, M, Franke, A, Franks, PW, Freedman, B, Gasparini, P, Gieger, C, Girotto, G, Goddard, ME, Golightly, YM, Gonzalez-Villalpando, C, Gordon-Larsen, P, Grallert, H, Grant, SFA, Grarup, N, Griffiths, L, Gudnason, V, Haiman, C, Hakonarson, H, Hansen, T, Hartman, CA, Hattersley, AT, Hayward, C, Heckbert, SR, Heng, C-K, Hengstenberg, C, Hewitt, AW, Hishigaki, H, Hoyng, CB, Huang, PL, Huang, W, Hunt, SC, Hveem, K, Hypponen, E, Iacono, WG, Ichihara, S, Ikram, MA, Isasi, CR, Jackson, RD, Jarvelin, M-R, Jin, Z-B, Jockel, K-H, Joshi, PK, Jousilahti, P, Jukema, JW, Kahonen, M, Kamatani, Y, Kang, KD, Kaprio, J, Kardia, SLR, Karpe, F, Kato, N, Kee, F, Kessler, T, Khera, A, Khor, CC, Kiemeney, LALM, Kim, B-J, Kim, EK, Kim, H-L, Kirchhof, P, Kivimaki, M, Koh, W-P, Koistinen, HA, Kolovou, GD, Kooner, JS, Kooperberg, C, Kottgen, A, Kovacs, P, Kraaijeveld, A, Kraft, P, Krauss, RM, Kumari, M, Kutalik, Z, Laakso, M, Lange, LA, Langenberg, C, Launer, LJ, Le Marchand, L, Lee, H, Lee, NR, Lehtimaki, T, Li, H, Li, L, Lieb, W, Lin, X, Lind, L, Linneberg, A, Liu, C-T, Loeffler, M, London, B, Lubitz, SA, Lye, SJ, Mackey, DA, Magi, R, Magnusson, PKE, Marcus, GM, Vidal, PM, Martin, NG, Marz, W, Matsuda, F, McGarrah, RW, McGue, M, McKnight, AJ, Medland, SE, Mellstrom, D, Metspalu, A, Mitchell, BD, Mitchell, P, Mook-Kanamori, DO, Morris, AD, Mucci, LA, Munroe, PB, Nalls, MA, Nazarian, S, Nelson, AE, Neville, MJ, Newton-Cheh, C, Nielsen, CS, Nothen, MM, Ohlsson, C, Oldehinkel, AJ, Orozco, L, Pahkala, K, Pajukanta, P, Palmer, CNA, Parra, EJ, Pattaro, C, Pedersen, O, Pennell, CE, Penninx, BWJH, Perusse, L, Peters, A, Peyser, PA, Porteous, DJ, Posthuma, D, Power, C, Pramstaller, PP, Province, MA, Qi, Q, Qu, J, Rader, DJ, Raitakari, OT, Ralhan, S, Rallidis, LS, Rao, DC, Redline, S, Reilly, DF, Reiner, AP, Rhee, SY, Ridker, PM, Rienstra, M, Ripatti, S, Ritchie, MD, Roden, DM, Rosendaal, FR, Rotter, J, Rudan, I, Rutters, F, Sabanayagam, C, Saleheen, D, Salomaa, V, Samani, NJ, Sanghera, DK, Sattar, N, Schmidt, B, Schmidt, H, Schmidt, R, Schulze, MB, Schunkert, H, Scott, LJ, Scott, RJ, Sever, P, Shiroma, EJ, Shoemaker, MB, Shu, X-O, Simonsick, EM, Sims, M, Singh, JR, Singleton, AB, Sinner, MF, Smith, JG, Snieder, H, Spector, TD, Stampfer, MJ, Stark, KJ, Strachan, DP, t' Hart, LM, Tabara, Y, Tang, H, Tardif, J-C, Thanaraj, TA, Timpson, NJ, Tonjes, A, Tremblay, A, Tuomi, T, Tuomilehto, J, Tusie-Luna, M-T, Uitterlinden, AG, van Dam, RM, van der Harst, P, Van der Velde, N, van Duijn, CM, van Schoor, NM, Vitart, V, Volker, U, Vollenweider, P, Volzke, H, Wacher-Rodarte, NH, Walker, M, Wang, YX, Wareham, NJ, Watanabe, RM, Watkins, H, Weir, DR, Werge, TM, Widen, E, Wilkens, LR, Willemsen, G, Willett, WC, Wilson, JF, Wong, T-Y, Woo, J-T, Wright, AF, Wu, J-Y, Xu, H, Yajnik, CS, Yokota, M, Yuan, J-M, Zeggini, E, Zemel, BS, Zheng, W, Zhu, X, Zmuda, JM, Zonderman, AB, Zwart, J-A, Chasman, D, Cho, YS, Heid, IM, McCarthy, M, Ng, MCY, O'Donnell, CJ, Rivadeneira, F, Thorsteinsdottir, U, Sun, Y, Tai, ES, Boehnke, M, Deloukas, P, Justice, AE, Lindgren, CM, Loos, RJF, Mohlke, KL, North, KE, Stefansson, K, Walters, RG, Winkler, TW, Young, KL, Loh, P-R, Esko, T, Assimes, TL, Auton, A, Abecasis, GR, Willer, CJ, Locke, AE, Berndt, S, Lettre, G, Frayling, TM, Okada, Y, Wood, AR, Visscher, PM, and Hirschhorn, JN
- Abstract
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated with height account for nearly all of the common SNP-based heritability. These SNPs are clustered within 7,209 non-overlapping genomic segments with a mean size of around 90 kb, covering about 21% of the genome. The density of independent associations varies across the genome and the regions of increased density are enriched for biologically relevant genes. In out-of-sample estimation and prediction, the 12,111 SNPs (or all SNPs in the HapMap 3 panel2) account for 40% (45%) of phenotypic variance in populations of European ancestry but only around 10-20% (14-24%) in populations of other ancestries. Effect sizes, associated regions and gene prioritization are similar across ancestries, indicating that reduced prediction accuracy is likely to be explained by linkage disequilibrium and differences in allele frequency within associated regions. Finally, we show that the relevant biological pathways are detectable with smaller sample sizes than are needed to implicate causal genes and variants. Overall, this study provides a comprehensive map of specific genomic regions that contain the vast majority of common height-associated variants. Although this map is saturated for populations of European ancestry, further research is needed to achieve equivalent saturation in other ancestries.
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- 2022
36. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles
- Author
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Hautakangas, H. (Heidi), Winsvold, B. S. (Bendik S.), Ruotsalainen, S. E. (Sanni E.), Bjornsdottir, G. (Gyda), Harder, A. V. (Aster V. E.), Kogelman, L. J. (Lisette J. A.), Thomas, L. F. (Laurent F.), Noordam, R. (Raymond), Benner, C. (Christian), Gormley, P. (Padhraig), Artto, V. (Ville), Banasik, K. (Karina), Bjornsdottir, A. (Anna), Boomsma, D. I. (Dorret, I), Brumpton, B. M. (Ben M.), Burgdorf, K. S. (Kristoffer Solvsten), Buring, J. E. (Julie E.), Chalmer, M. A. (Mona Ameri), de Boer, I. (Irene), Dichgans, M. (Martin), Erikstrup, C. (Christian), Färkkilä, M. (Markus), Garbrielsen, M. E. (Maiken Elvestad), Ghanbari, M. (Mohsen), Hagen, K. (Knut), Häppölä, P. (Paavo), Hottenga, J.-J. (Jouke-Jan), Hrafnsdottir, M. G. (Maria G.), Hveem, K. (Kristian), Johnsen, M. B. (Marianne Bakke), Kähönen, M. (Mika), Kristoffersen, E. S. (Espen S.), Kurth, T. (Tobias), Lehtimäki, T. (Terho), Lighart, L. (Lannie), Magnusson, S. H. (Sigurdur H.), Malik, R. (Rainer), Pedersen, O. B. (Ole Birger), Pelzer, N. (Nadine), Penninx, B. W. (Brenda W. J. H.), Ran, C. (Caroline), Ridker, P. M. (Paul M.), Rosendaal, F. R. (Frits R.), Sigurdardottir, G. R. (Gudrun R.), Skogholt, A. H. (Anne Heidi), Sveinsson, O. A. (Olafur A.), Thorgeirsson, T. E. (Thorgeir E.), Ullum, H. (Henrik), Vijfhuizen, L. S. (Lisanne S.), Widen, E. (Elisabeth), van Dijk, K. W. (Ko Willems), International Headache Genetics Consortium, HUNT All-in Headache, Danish Blood Donor Study Genomic Cohort, Aromaa, A. (Arpo), Belin, A. C. (Andrea Carmine), Freilinger, T. (Tobias), Ikram, M. A. (M. Arfan), Järvelin, M.-R. (Marjo-Riitta), Raitakari, O. T. (Olli T.), Terwindt, G. M. (Gisela M.), Kallela, M. (Mikko), Wessman, M. (Maija), Olesen, J. (Jes), Chasman, D. I. (Daniel, I), Nyholt, D. R. (Dale R.), Stefansson, H. (Hreinn), Stefansson, K. (Kari), van den Maagdenberg, A. M. (Arn M. J. M.), Hansen, T. F. (Thomas Folkmann), Ripatti, S. (Samuli), Zwart, J.-A. (John-Anker), Palotie, A. (Aarno), Pirinen, M. (Matti), Hautakangas, H. (Heidi), Winsvold, B. S. (Bendik S.), Ruotsalainen, S. E. (Sanni E.), Bjornsdottir, G. (Gyda), Harder, A. V. (Aster V. E.), Kogelman, L. J. (Lisette J. A.), Thomas, L. F. (Laurent F.), Noordam, R. (Raymond), Benner, C. (Christian), Gormley, P. (Padhraig), Artto, V. (Ville), Banasik, K. (Karina), Bjornsdottir, A. (Anna), Boomsma, D. I. (Dorret, I), Brumpton, B. M. (Ben M.), Burgdorf, K. S. (Kristoffer Solvsten), Buring, J. E. (Julie E.), Chalmer, M. A. (Mona Ameri), de Boer, I. (Irene), Dichgans, M. (Martin), Erikstrup, C. (Christian), Färkkilä, M. (Markus), Garbrielsen, M. E. (Maiken Elvestad), Ghanbari, M. (Mohsen), Hagen, K. (Knut), Häppölä, P. (Paavo), Hottenga, J.-J. (Jouke-Jan), Hrafnsdottir, M. G. (Maria G.), Hveem, K. (Kristian), Johnsen, M. B. (Marianne Bakke), Kähönen, M. (Mika), Kristoffersen, E. S. (Espen S.), Kurth, T. (Tobias), Lehtimäki, T. (Terho), Lighart, L. (Lannie), Magnusson, S. H. (Sigurdur H.), Malik, R. (Rainer), Pedersen, O. B. (Ole Birger), Pelzer, N. (Nadine), Penninx, B. W. (Brenda W. J. H.), Ran, C. (Caroline), Ridker, P. M. (Paul M.), Rosendaal, F. R. (Frits R.), Sigurdardottir, G. R. (Gudrun R.), Skogholt, A. H. (Anne Heidi), Sveinsson, O. A. (Olafur A.), Thorgeirsson, T. E. (Thorgeir E.), Ullum, H. (Henrik), Vijfhuizen, L. S. (Lisanne S.), Widen, E. (Elisabeth), van Dijk, K. W. (Ko Willems), International Headache Genetics Consortium, HUNT All-in Headache, Danish Blood Donor Study Genomic Cohort, Aromaa, A. (Arpo), Belin, A. C. (Andrea Carmine), Freilinger, T. (Tobias), Ikram, M. A. (M. Arfan), Järvelin, M.-R. (Marjo-Riitta), Raitakari, O. T. (Olli T.), Terwindt, G. M. (Gisela M.), Kallela, M. (Mikko), Wessman, M. (Maija), Olesen, J. (Jes), Chasman, D. I. (Daniel, I), Nyholt, D. R. (Dale R.), Stefansson, H. (Hreinn), Stefansson, K. (Kari), van den Maagdenberg, A. M. (Arn M. J. M.), Hansen, T. F. (Thomas Folkmann), Ripatti, S. (Samuli), Zwart, J.-A. (John-Anker), Palotie, A. (Aarno), and Pirinen, M. (Matti)
- Abstract
Migraine affects over a billion individuals worldwide but its genetic underpinning remains largely unknown. Here, we performed a genome-wide association study of 102,084 migraine cases and 771,257 controls and identified 123 loci, of which 86 are previously unknown. These loci provide an opportunity to evaluate shared and distinct genetic components in the two main migraine subtypes: migraine with aura and migraine without aura. Stratification of the risk loci using 29,679 cases with subtype information indicated three risk variants that seem specific for migraine with aura (in HMOX2, CACNA1A and MPPED2), two that seem specific for migraine without aura (near SPINK2 and near FECH) and nine that increase susceptibility for migraine regardless of subtype. The new risk loci include genes encoding recent migraine-specific drug targets, namely calcitonin gene-related peptide (CALCA/CALCB) and serotonin 1F receptor (HTR1F). Overall, genomic annotations among migraine-associated variants were enriched in both vascular and central nervous system tissue/cell types, supporting unequivocally that neurovascular mechanisms underlie migraine pathophysiology.
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- 2022
37. Successful treatment of psoriasis with adalimumab induced no changes in the gut microbiota
- Author
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Todberg, T., Egeberg, A., Zachariae, C., Sørensen, N., Pedersen, O., Skov, L., Todberg, T., Egeberg, A., Zachariae, C., Sørensen, N., Pedersen, O., and Skov, L.
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- 2022
38. Exploring farmers’ perception, knowledge, and management techniques of salt-affected soils to enhance rice production on small land holdings in Tanzania
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Omar, M. M., Shitindi, M. J., Massawe, B. H. J., Fue, K. G., Pedersen, O., Meliyo, J. L., Omar, M. M., Shitindi, M. J., Massawe, B. H. J., Fue, K. G., Pedersen, O., and Meliyo, J. L.
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- 2022
39. The temporal association of hyperhidrosis and its comorbidities – a nationwide hospital-based cohort study
- Author
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Henning, M. A.S., Reguant, R., Jørgensen, I. F., Andersen, R. K., Ibler, K. S., Pedersen, O. B., Jemec, G.B.E., Brunak, S., Henning, M. A.S., Reguant, R., Jørgensen, I. F., Andersen, R. K., Ibler, K. S., Pedersen, O. B., Jemec, G.B.E., and Brunak, S.
- Abstract
Background: Research on hyperhidrosis comorbidities has documented the co-occurrence of diseases but has not provided information about temporal disease associations. Objective: To investigate the temporal disease trajectories of individuals with hospital-diagnosed hyperhidrosis. Methods: This is a hospital-based nationwide cohort study including all patients with a hospital contact in Denmark between 1994 and 2018. International Classification of Diseases version-10 diagnoses assigned to inpatients, outpatients and emergency department patients were collected from the Danish National Patient Register. The main outcome was the temporal disease associations occurring in individuals with hyperhidrosis, which was assessed by identifying morbidities significantly associated with hyperhidrosis and then examining whether there was a significant order of these diagnoses using binomial tests. Results: Overall, 7 191 519 patients were included. Of these, 8758 (0.12%) patients had localized hyperhidrosis (5674 female sex [64.8%]; median age at first diagnosis 26.9 [interquartile range 21.3–36.1]) and 1102 (0.015%) generalized hyperhidrosis (606 female sex [59.9%]; median age at first diagnosis 40.9 [interquartile range 26.4–60.7]). The disease trajectories comprised pain complaints, stress, epilepsy, respiratory and psychiatric diseases. The most diagnosed morbidities for localized hyperhidrosis were abdominal pain (relative risk [RR] = 121.75; 95% Confidence Interval [CI] 121.14–122.35; P < 0.001), soft tissue disorders (RR = 151.19; 95% CI 149.58–152.80; P < 0.001) and dorsalgia (RR = 160.15; 95% CI 158.92–161.38; P < 0.001). The most diagnosed morbidities for generalized hyperhidrosis were dorsalgia (RR = 306.59; 95% CI 302.17–311.02; P < 0.001), angina pectoris (RR = 411.69; 95% CI 402.23–421.16; P < 0.001) and depression (RR = 207.92; 95% CI 202.21–213.62; P < 0.001). All these morbidities were diagnosed before hyperhidrosis. Conclusions: This paper
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- 2022
40. Low irradiance disrupts the internal O2 dynamics of seagrass (Thalassia testudinum) leading to shoot meristem H2S intrusion
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Koch, M. S., Johnson, C. R., Madden, C. J., Pedersen, O., Koch, M. S., Johnson, C. R., Madden, C. J., and Pedersen, O.
- Abstract
Hypoxia and hydrogen sulfide (H2S) intrusion at night contribute to large-scale seagrass mortality events worldwide. Declining water quality has lowered irradiance and enhanced hypoxia in seagrass ecosystems, but linkages between low irradiance and seagrass internal pO2 in situ are not well understood. We examined low irradiance effects on leaf and meristem pO2 dynamics of a dominant tropical seagrass, Thalassia testudinum, using microsensors over multiple diurnal cycles. Further, we determined how O2 dynamics affect H2S intrusion into shoot meristems under low irradiance. Sequential days of low irradiance disrupted internal leaf O2 status in three ways: i) causing a longer lag in morning O2 pressurization, ii) depressing maximum pO2 during the day, and iii) shortening the time where maximum pO2 was sustained into the afternoon. There was a close relationship between leaf and water column pO2 during the day (R2 = 0.93 +/- 0.09); thus, internal O2 dynamics appear more dependent on water column pO2 under low irradiance. The nighttime minimum of leaf and meristem pO2 (1.2 and 0.4 kPa, respectively) were very low and the length of time the meristem sustained hypoxia (< 1.5 kPa pO2) at night was high (9:40 h:min). H2S intrusion into the meristem at night following 24-48 h of shading was persistent, likely the combined effect of limited internal O2 flow without saturating irradiances for photosynthesis, and a breakdown of the sediment oxic microshield. Under low irradiance, more frequent intrusions of H2S to the meristems increases the chances of large-scale seagrass mortality events at night.
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- 2022
41. The impact of age on the 99th percentile of cardiac troponin
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Hasselbalch, R, Strandkjaer, N, Kristensen, J, Joergensen, N, Kock, T O, Rye Ostrowski, S, Vesterager Pedersen, O B, Torp-pedersen, C, Bundgaard, H, Bor, V, Afzal, S, Kamstrup, P, Dahl, M, Hilsted, L, Iversen, K I, Hasselbalch, R, Strandkjaer, N, Kristensen, J, Joergensen, N, Kock, T O, Rye Ostrowski, S, Vesterager Pedersen, O B, Torp-pedersen, C, Bundgaard, H, Bor, V, Afzal, S, Kamstrup, P, Dahl, M, Hilsted, L, and Iversen, K I
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Introduction The 99th percentile upper reference limit (URL) of cardiac troponin (cTn) is diagnostic cutoff for myocardial infarction (MI). Several factors are known to lead to an increase in cTn including sex, kidney function, left ventricular function and various comorbidities. Similarly, studies have shown that cTn concentration of patients increase with age. However, the impact of age on the concentration of cTn in healthy individuals is unclear as several studies of healthy populations showed little to no impact of age. Purpose To determine the effect of age on the URL of cTn for the Danish population. Methods We invited active and retired blood donors with the aim of including 250 participants of each sex in each of four age groups, <50, 50–60, 60–70 and >70 years, for a total of about 2000 participants. cTn levels were measured by 4 cTn assays (Siemens Atellica and Vista cTnI, Roche cTnT and Abbott Alinity cTnI). The age specific URL were calculated using the non-parametric method. Quantile regression for the 99th percentile was adjusted for sex and creatinine concentration. Results A total of 2287 participants were sampled in the study, of which 4 (0.2%) were excluded due to a history of heart disease and 7 (0.3%) were excluded due to insufficient plasma for screening biomarkers. The median age was 58.6 (IQR 48.2–69.7), and 52.6% were female. Figure 1 shows the distribution of cTn concentrations in age intervals. There was a significant increase in cTn with age for all assays (all p<0.001). After adjusting for sex and creatinine concentration, increasing age was only significantly associated with cTnT (0.40 ng/L increase per year, p=0.03). Figure 2 panel A shows the age specific URL for each assay, where we observed a significant difference for cTnT with the URL increasing from 15.8 ng/L (90% CI 12.4–33.9 ng/L) for participants <50 years to 37.6 ng/L (90% CI 34.6–41.5 ng/L) for participants >70 years.
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- 2022
42. Low vs. high haemoglobin trigger for transfusion in vascular surgery: protocol for a randomised trial
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Møller, A., Nielsen, H. B., Wetterslev, J., Pedersen, O. B., Hellemann, D., and Shahidi, S.
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- 2017
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43. Blood donation and iron deficiency
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Rigas, A. S., Pedersen, O. B., Erikstrup, C., Hjalgrim, H., and Ullum, H.
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- 2017
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44. Fatigue and Associated Microstructural Aspects : Atomistically Based Multiscale Modelling
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Pedersen, O. B., Lépinoux, Joël, editor, Mazière, Dominique, editor, Pontikis, Vassilis, editor, and Saada, Georges, editor
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- 2000
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45. Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study
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Mor, A, Antonsen, S, Kahlert, J, Holsteen, V, Jørgensen, S, Holm-Pedersen, J, Sørensen, H T, Pedersen, O, and Ehrenstein, V
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- 2015
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46. OSTEOARTHRITIS PATIENTS ARE NOT ALL CAST IN THE SAME MOULD: GENETIC ASSOCIATIONS OF KNEE AND HIP OSTEOARTHRITIS DIFFER BETWEEN PATIENTS WHO HAVE UNDERGONE JOINT REPLACEMENT AND PATIENTS WHO HAVE NOT
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Henkel, C., primary, Styrkársdóttir, U., additional, Pedersen, O., additional, Stefánsson, K., additional, and Troelsen, A., additional
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- 2022
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47. Successful treatment of psoriasis with adalimumab induced no changes in the gut microbiota
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Todberg, T., primary, Egeberg, A., additional, Zachariae, C., additional, Sørensen, N., additional, Pedersen, O., additional, and Skov, L., additional
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- 2022
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48. Natural variation of submergence tolerance among Arabidopsis thaliana accessions
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Vashisht, D., Hesselink, A., Pierik, R., Ammerlaan, J. M. H., Bailey-Serres, J., Visser, E. J. W., Pedersen, O., van Zanten, M., Vreugdenhil, D., Jamar, D. C. L., Voesenek, L. A. C. J., and Sasidharan, R.
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- 2011
49. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project: rationale and planned nationwide studies of genetic predictors, physical exercise, and individualized pharmacological treatment
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Steffensen C, Thomsen RW, Vaag A, Beck-Nielsen H, Christiansen JS, Hansen T, Pedersen O, and Rungby J
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Infectious and parasitic diseases ,RC109-216 - Abstract
Charlotte Steffensen,1 Reimar W Thomsen,2 Allan Vaag,3 Henning Beck-Nielsen,4 Jens Sandahl Christiansen,1 Torben Hansen,5,6 Oluf Borbye Pedersen,5,6 Jørgen Rungby11Aarhus University Hospital, Department of Medicine, Aarhus, 2Aarhus University Hospital, Institute of Clinical Medicine, Department of Clinical Epidemiology, Aarhus, 3Copenhagen University Hospital "Rigshospitalet", Department of Endocrinology, Copenhagen, 4Odense University Hospital, Department of Endocrinology, Odense, 5The Novo Nordisk Foundation Centre for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, 6Faculty of Health Sciences, University of Aarhus, Aarhus, DenmarkAbstract: Here we provide an overview of the rationale and methods of a series of planned population based studies within the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project. The project aims to support and evaluate ongoing political and administrative efforts to implement nationwide guidelines for maintaining metabolic control in newly diagnosed type 2 diabetes (T2D) patients to prevent diabetic complications and improve quality of life. The DD2 is designed as a prospective cohort study (collection of epidemiological data) supplemented by randomized clinical intervention trials (on physical exercise and individualized pharmacological treatment) and the establishment of a biobank comprised of material from a large number of newly diagnosed T2D patients. Inclusion of the majority of newly diagnosed T2D patients as they are diagnosed at their general practitioner or diabetes hospital outpatient clinics and entered into the DD2 cohort will establish a nationwide database comprising a large number of future incident cases of T2D in Denmark. These cases will form the project cohort of the DD2. Within the first 6 months of diagnosis, all patients will be invited to contribute to a biobank of DNA, plasma, urine, and tissue sampling. The DNA biobank will enable future studies of the effect of pharmacological treatment and outcome in subsets of patients with specific genetic risk profiles covering disease etiology and specific drug kinetics and metabolism. We will also perform two clinical intervention trials examining: the effectiveness of physical exercise on diabetes-related outcomes and the impact of trial outcomes on individualized pharmacological treatment. Moreover, the DD2 will serve as a platform for testing and developing new antidiabetic drugs. All together, we expect this study to contribute to substantially improved diabetes care in T2D patients locally and abroad.Keywords: type 2 diabetes, prognosis, intervention, physical exercise
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- 2012
50. Combinatorial, additive and dose-dependent drug-microbiome associations
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Forslund, SK, Chakaroun, R, Zimmermann-Kogadeeva, M, Markó, L, Aron-Wisnewsky, J, Nielsen, T, Moitinho-Silva, L, Schmidt, TSB, Falony, G, Vieira-Silva, S, Adriouch, S, Alves, RJ, Assmann, K, Bastard, J-P, Birkner, T, Caesar, R, Chilloux, J, Coelho, LP, Fezeu, L, Galleron, N, Helft, G, Isnard, R, Ji, B, Kuhn, M, Le Chatelier, E, Myridakis, A, Olsson, L, Pons, N, Prifti, E, Quinquis, B, Roume, H, Salem, J-E, Sokolovska, N, Tremaroli, V, Valles-Colomer, M, Lewinter, C, Søndertoft, NB, Pedersen, HK, Hansen, TH, Amouyal, C, Andersson Galijatovic, EA, Andreelli, F, Barthelemy, O, Batisse, J-P, Belda, E, Berland, M, Bittar, R, Blottière, H, Bosquet, F, Boubrit, R, Bourron, O, Camus, M, Cassuto, D, Ciangura, C, Collet, J-P, Dao, M-C, Djebbar, M, Doré, A, Engelbrechtsen, L, Fellahi, S, Fromentin, S, Galan, P, Gauguier, D, Giral, P, Hartemann, A, Hartmann, B, Holst, JJ, Hornbak, M, Hoyles, L, Hulot, J-S, Jaqueminet, S, Jørgensen, NR, Julienne, H, Justesen, J, Kammer, J, Krarup, N, Kerneis, M, Khemis, J, Kozlowski, R, Lejard, V, Levenez, F, Lucas-Martini, L, Massey, R, Martinez-Gili, L, Maziers, N, Medina-Stamminger, J, Montalescot, G, Moute, S, Neves, AL, Olanipekun, M, Le Pavin, LP, Poitou, C, Pousset, F, Pouzoulet, L, Rodriguez-Martinez, A, Rouault, C, Silvain, J, Svendstrup, M, Swartz, T, Vanduyvenboden, T, Vatier, C, Walther, S, Gøtze, JP, Køber, L, Vestergaard, H, Hansen, T, Zucker, J-D, Hercberg, S, Oppert, J-M, Letunic, I, Nielsen, J, Bäckhed, F, Ehrlich, SD, Dumas, M-E, Raes, J, Pedersen, O, Clément, K, Stumvoll, M, Bork, P, The MetaCardis Consortium (Hoyles, L.), European Molecular Biology Laboratory [Heidelberg] (EMBL), Max Delbrück Center for Molecular Medicine [Berlin] (MDC), Helmholtz-Gemeinschaft = Helmholtz Association, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Berlin Institute of Health (BIH), German Center for Cardiovascular Research (DZHK), Universität Leipzig, Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), University of Copenhagen = Københavns Universitet (UCPH), University of New South Wales [Sydney] (UNSW), Paul Scherrer Institute (PSI), Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Heidelberg University, Equipe 3: EREN- Equipe de Recherche en Epidémiologie Nutritionnelle (CRESS - U1153), Université Sorbonne Paris Nord-Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Henri Mondor [Créteil], Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], University of Gothenburg (GU), Imperial College London, MetaGenoPolis (MGP (US 1367)), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Paris-Saclay, Institut de cardiologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Chalmers University of Technology [Gothenburg, Sweden], Unité de modélisation mathématique et informatique des systèmes complexes [Bondy] (UMMISCO), Université de Yaoundé I-Institut de la francophonie pour l'informatique-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Université Gaston Bergé (Saint-Louis, Sénégal)-Université Cadi Ayyad [Marrakech] (UCA)-Sorbonne Université (SU)-Institut de Recherche pour le Développement (IRD [France-Nord]), Centre d'investigation clinique Paris Est [CHU Pitié Salpêtrière] (CIC Paris-Est), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Biobyte Solutions [Heidelberg, Germany] (BS), IT University of Copenhagen (ITU), Sahlgrenska University Hospital [Gothenburg], Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), National Heart and Lung Institute [London] (NHLI), Imperial College London-Royal Brompton and Harefield NHS Foundation Trust, McGill University and Genome Quebec Innovation Centre, Helmholtz Institute Ulm (HIU), Helmholtz Zentrum München = German Research Center for Environmental Health, University of Würzburg = Universität Würzburg, Yonsei University, MetaCardis Consortium*: Chloe Amouyal, Ehm Astrid Andersson Galijatovic, Fabrizio Andreelli, Olivier Barthelemy, Jean-Paul Batisse, Eugeni Belda, Magalie Berland, Randa Bittar, Hervé Blottière, Frederic Bosquet, Rachid Boubrit, Olivier Bourron, Mickael Camus, Dominique Cassuto, Cecile Ciangura, Jean-Philippe Collet, Maria-Carlota Dao, Morad Djebbar, Angélique Doré, Line Engelbrechtsen, Soraya Fellahi, Sebastien Fromentin, Pilar Galan, Dominique Gauguier, Philippe Giral, Agnes Hartemann, Bolette Hartmann, Jens Juul Holst, Malene Hornbak, Lesley Hoyles, Jean-Sebastien Hulot, Sophie Jaqueminet, Niklas Rye Jørgensen, Hanna Julienne, Johanne Justesen, Judith Kammer, Nikolaj Krarup, Mathieu Kerneis, Jean Khemis, Ruby Kozlowski, Véronique Lejard, Florence Levenez, Lea Lucas-Martini, Robin Massey, Laura Martinez-Gili, Nicolas Maziers, Jonathan Medina-Stamminger, Gilles Montalescot, Sandrine Moute, Ana Luisa Neves, Michael Olanipekun, Laetitia Pasero Le Pavin, Christine Poitou, Francoise Pousset, Laurence Pouzoulet, Andrea Rodriguez-Martinez, Christine Rouault, Johanne Silvain, Mathilde Svendstrup, Timothy Swartz, Thierry Vanduyvenboden, Camille Vatier, Stefanie Walther., ANR-16-IDEX-0004,ULNE,ULNE(2016), ANR-18-IBHU-0001,PreciDIAB,PreciDIAB Institute, the holistic approach of personal diabets care(2018), Dumas, Marc-Emmanuel, Universität Leipzig [Leipzig], Service de Nutrition [CHU Pitié-Salpétrière], Institut E3M [CHU Pitié-Salpêtrière], CHU Henri Mondor, Centre d'investigation clinique pluridisciplinaire [CHU Pitié Salpêtrière] (CIC-1901(ex CIC-1421)), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Imperial College London - National Heart and Lung Institute, and Division of Computational and Systems Medicine, Imperial College London, London, SW7 2AZ, UK
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Clostridiales ,Science & Technology ,Multidisciplinary ,ANTIBIOTIC USE ,IMPACT ,Microbiota ,[SDV]Life Sciences [q-bio] ,HUMAN GUT MICROBIOME ,Atherosclerosis ,Gastrointestinal Microbiome ,[SDV] Life Sciences [q-bio] ,Multidisciplinary Sciences ,PROTON PUMP INHIBITORS ,Cardiovascular and Metabolic Diseases ,GUIDELINE ,Metabolome ,MANAGEMENT ,Humans ,Science & Technology - Other Topics ,ALTERS - Abstract
During the transition from a healthy state to cardiometabolic disease, patients become heavily medicated, which leads to an increasingly aberrant gut microbiome and serum metabolome, and complicates biomarker discovery1-5. Here, through integrated multi-omics analyses of 2,173 European residents from the MetaCardis cohort, we show that the explanatory power of drugs for the variability in both host and gut microbiome features exceeds that of disease. We quantify inferred effects of single medications, their combinations as well as additive effects, and show that the latter shift the metabolome and microbiome towards a healthier state, exemplified in synergistic reduction in serum atherogenic lipoproteins by statins combined with aspirin, or enrichment of intestinal Roseburia by diuretic agents combined with beta-blockers. Several antibiotics exhibit a quantitative relationship between the number of courses prescribed and progression towards a microbiome state that is associated with the severity of cardiometabolic disease. We also report a relationship between cardiometabolic drug dosage, improvement in clinical markers and microbiome composition, supporting direct drug effects. Taken together, our computational framework and resulting resources enable the disentanglement of the effects of drugs and disease on host and microbiome features in multimedicated individuals. Furthermore, the robust signatures identified using our framework provide new hypotheses for drug-host-microbiome interactions in cardiometabolic disease. ispartof: NATURE vol:600 issue:7889 pages:500-+ ispartof: location:England status: published
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- 2021
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