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193 results on '"Pelà, Giovanna"'

2. Precipitating factors in patients with spontaneous coronary artery dissection: Clinical, laboratoristic and prognostic implications

Author

Gurgoglione, Filippo Luca, Rizzello, Davide, Giacalone, Rossella, Ferretti, Marco, Vezzani, Antonella, Pfleiderer, Bettina, Pelà, Giovanna, De Panfilis, Chiara, Cattabiani, Maria Alberta, Benatti, Giorgio, Tadonio, Iacopo, Grassi, Francesca, Magnani, Giulia, Noni, Manjola, Cancellara, Martina, Nicolini, Francesco, Ardissino, Diego, Vignali, Luigi, Niccoli, Giampaolo, and Solinas, Emilia

Published
2023
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4. Onset of ANCA-positive EGPA with bilateral pleural effusion: a case report.

Author

Marchese, Alessandra, Accogli, Rocco, Frizzelli, Annalisa, De Simoni, Alessandro, Bondarenko, Olha, Pisi, Roberta, Caramori, Gaetano, Pelà, Giovanna, Majori, Maria, Gnetti, Letizia, Aluia, Agnese, D'Aloisio, Lorenzo, Chetta, Alfredo, and Aiello, Marina

Abstract

Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic, immune-mediated disease that occurs in patients with asthma and eosinophilia. It is characterized by inflammation of small- and medium-caliber blood vessels. Case report: This report presents an unusual clinical case of EGPA with positive anti-neutrophil cytoplasmic antibodies who manifested bilateral pleural effusion. The diagnosis was confirmed through laboratory assessments and bronchial biopsies. The patient was treated with methylprednisolone showing improvement in symptoms. Conclusions: Our case appear interesting considering the limited evidence of pleural effusion in patients with EGPA documented in the literature. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Impact of COVID-19 on the cardiovascular health of women: a review by the Italian Society of Cardiology Working Group on ‘gender cardiovascular diseases’

Author

Moscucci, Federica, Gallina, Sabina, Bucciarelli, Valentina, Aimo, Alberto, Pelà, Giovanna, Cadeddu-Dessalvi, Christian, Nodari, Savina, Maffei, Silvia, Meloni, Antonella, Deidda, Martino, Mercuro, Giuseppe, Pedrinelli, Roberto, Penco, Maria, Sciomer, Susanna, and Vittoria Mattioli, Anna

Published
2022
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10. ALLiance for sEcondary PREvention after an acute coronary syndrome. The ALLEPRE trial: A multicenter fully nurse-coordinated intensive intervention program

Author

Paoli, Giorgia, Notarangelo, Maria Francesca, Mattioli, Maria, La Sala, Rachele, Foà, Chiara, Solinas, Emilia, Fusco, Sara, Fava, Cristian, Caminiti, Caterina, Artioli, Giovanna, Pelà, Giovanna, Dall’Aglio, Elisabetta, Manari, Antonio, Tondi, Stefano, Rizzo, Antonio, Trapolin, Gaia, Patrizi, Giampiero, Cappelli, Stefano, Villani, Giovanni Quinto, Piepoli, Massimo, Zobbi, Gianni, Nicosia, Elisa, and Ardissino, Diego

Published
2018
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15. 220 MANAGING CARDIAC ARREST SECONDARY TO SPONTANEOUS CORONARY ARTERY DISSECTION: SHOULD WE ROUTINELY CONSIDER ICD IMPLANTATION?

Author

Rizzello, Davide, primary, Gurgoglione, Filippo Luca, additional, Giacalone, Rossella, additional, Ferretti, Marco, additional, Noni, Manjola, additional, Pelà, Giovanna, additional, Cattabiani, Maria Alberta, additional, Benatti, Giorgio, additional, Tadonio, Iacopo, additional, Ardissino, Diego, additional, Niccoli, Giampaolo, additional, Vignali, Luigi, additional, and Solinas, Emilia, additional

Published
2022
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16. An Impairment in Resting and Exertional Breathing Pattern May Occur in Long-COVID Patients with Normal Spirometry and Unexplained Dyspnoea

Author

Frizzelli, Annalisa, primary, Di Spigno, Francesco, additional, Moderato, Luca, additional, Halasz, Geza, additional, Aiello, Marina, additional, Tzani, Panagiota, additional, Manari, Gaia, additional, Calzetta, Luigino, additional, Pisi, Roberta, additional, Pelà, Giovanna, additional, Piepoli, Massimo, additional, and Chetta, Alfredo, additional

Published
2022
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18. Sex-Related Differences in Long-COVID-19 Syndrome

Author

Pelà, Giovanna, primary, Goldoni, Matteo, additional, Solinas, Emila, additional, Cavalli, Chiara, additional, Tagliaferri, Sara, additional, Ranzieri, Silvia, additional, Frizzelli, Annalisa, additional, Marchi, Laura, additional, Mori, Pier Anselmo, additional, Majori, Maria, additional, Aiello, Marina, additional, Corradi, Massimo, additional, and Chetta, Alfredo, additional

Published
2022
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20. Looking for Optimal Antithrombotic Strategy after Transcatheter Left Atrial Appendage Occlusion: A Real-World Comparison of Different Antiplatelet Regimens

Author

Vignali, Luigi, primary, Gurgoglione, Filippo Luca Luca, additional, Barocelli, Federico, additional, Cattabiani, Maria Alberta, additional, Solinas, Emilia, additional, Maini, Arianna, additional, Tadonio, Iacopo, additional, Benatti, Giorgio, additional, Pelà, Giovanna, additional, Coli, Stefano, additional, Ardissino, Diego, additional, and Niccoli, Giampaolo, additional

Published
2022
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21. Distribution of the Clinical Manifestations of Alpha 1 Antitrypsin Deficiency in Respiratory Outpatients from an Area of Northern Italy

Author

Aiello, Marina, primary, Marchi, Laura, additional, Ferrarotti, Ilaria, additional, Frizzelli, Annalisa, additional, Pisi, Roberta, additional, Calzetta, Luigino, additional, Manari, Gaia, additional, Pelà, Giovanna, additional, Russo, Annalisa, additional, Minerba, Roberta, additional, Aloe, Rosalia, additional, Ranzieri, Silvia, additional, Corradi, Massimo, additional, and Chetta, Alfredo, additional

Published
2022
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23. 301 Long term sequelae after COVID-19: the different impact on the right and left ventricles

Author

Pelà, Giovanna, primary, Aiello, Marina, additional, Goldoni, Matteo, additional, Cavalli, Chiara, additional, Perrino, Felice, additional, Mantovanelli, Luca, additional, Frizzelli, Annalisa, additional, Letizia, Davide Maria, additional, Tagliaferri, Sara, additional, Pizzi, Valentina, additional, Mori, Pier Anselmo, additional, Majori, Maria, additional, Sverzellati, Nicola, additional, Corradi, Massimo, additional, and Chetta, Alfredo, additional

Published
2021
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24. 308 Sex-related differences in long COVID-19 syndrome

Author

Pelà, Giovanna, primary, Aiello, Marina, additional, Solinas, Emilia, additional, Mantovanelli, Luca, additional, Cavalli, Chiara, additional, Tagliaferri, Sara, additional, Ranzieri, Silvia, additional, Frizzelli, Annalisa, additional, Marchi, Laura, additional, Corradi, Massimo, additional, Mori, Pier Anselmo, additional, Majori, Maria, additional, Goldoni, Matteo, additional, and Chetta, Alfredo, additional

Published
2021
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25. 240 Left atrial appendage occlusion: safety, efficacy, and antiplatelet therapy in a single-centre experience

Author

Vignali, Luigi, primary, Barocelli, Federico, additional, Gurgoglione, Filippo Luca, additional, Cattabiani, Maria Alberta, additional, Maini, Arianna, additional, Solinas, Emilia, additional, Benatti, Giorgio, additional, Tadonio, Iacopo, additional, Coli, Stefano, additional, Pelà, Giovanna Maria, additional, and Niccoli, Giampaolo, additional

Published
2021
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26. Long-Term Cardiac Sequelae in Patients Referred into a Diagnostic Post-COVID-19 Pathway: The Different Impacts on the Right and Left Ventricles

Author

Pelà, Giovanna, primary, Goldoni, Matteo, additional, Cavalli, Chiara, additional, Perrino, Felice, additional, Tagliaferri, Sara, additional, Frizzelli, Annalisa, additional, Mori, Pier Anselmo, additional, Majori, Maria, additional, Aiello, Marina, additional, Sverzellati, Nicola, additional, Corradi, Massimo, additional, and Chetta, Alfredo, additional

Published
2021
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27. Coronavirus Disease 2019: COSeSco – A Risk Assessment Score to Predict the Risk of Pulmonary Sequelae in COVID-19 Patients

Author

Aiello, Marina, primary, Marchi, Laura, additional, Calzetta, Luigino, additional, Speroni, Silvia, additional, Frizzelli, Annalisa, additional, Ghirardini, Marianna, additional, Celiberti, Valentina, additional, Sverzellati, Nicola, additional, Majori, Maria, additional, Mori, Pier Anselmo, additional, Ranzieri, Silvia, additional, Pisi, Roberta, additional, Pelà, Giovanna, additional, Corradi, Massimo, additional, and Chetta, Alfredo, additional

Published
2021
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28. Idiopathic pulmonary fibrosis and occupational risk factors

Author

Ranzieri, Silvia, Illica Magrini, Elisa, Mozzoni, Paola, Andreoli, Roberta, Pelà, Giovanna, Bertorelli, Giuseppina, and Corradi, Massimo

Subjects
environmental factors, Risk Factors, Occupational Exposure, lung fibrosis, occupation, Humans, Original Article, Idiopathic pulmonary fibrosis, Dust, occupational factors, respiratory system, respiratory tract diseases
Abstract

Idiopathic pulmonary fibrosis (IPF) is a rare lung disease of unknown origin that rapidly leads to death. However, the rate of disease progression varies from one individual to another and is still difficult to predict. The prognosis of IPF is poor, with a median survival of three to five years after diagnosis, without curative therapies other than lung transplantation. The factors leading to disease onset and progression are not yet completely known. The current disease paradigm is that sustained alveolar epithelial micro-injury caused by environmental triggers (e.g., cigarette smoke, microaspiration of gastric content, particulate dust, viral infections or lung microbial composition) leads to alveolar damage resulting in fibrosis in genetically susceptible individuals. Numerous epidemiological studies and case reports have shown that occupational factors contribute to the risk of developing IPF. In this perspective, we briefly review the current understanding of the pathophysiology of IPF and the importance of occupational factors in the pathogenesis and prognosis of the disease. Prompt identification and elimination of occult exposure may represent a novel treatment approach in patients with IPF.

Published
2019

30. Determinants of cardiac structure in frail and sarcopenic elderly adults

Author

Pelà, Giovanna, primary, Tagliaferri, Sara, additional, Perrino, Felice, additional, Righelli, Ilaria, additional, Montanari, Rossella, additional, Longobucco, Yari, additional, Salvi, Marco, additional, Calvani, Riccardo, additional, Cesari, Matteo, additional, Cherubini, Antonio, additional, Bernabei, Roberto, additional, Di Bari, Mauro, additional, Landi, Francesco, additional, Marzetti, Emanuele, additional, Lauretani, Fulvio, additional, and Maggio, Marcello, additional

Published
2021
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33. Comprehensive Model for Physical and Cognitive Frailty: Current Organization and Unmet Needs

Author

Lauretani, Fulvio, primary, Longobucco, Yari, additional, Ferrari Pellegrini, Francesca, additional, De Iorio, Aurelio Maria, additional, Fazio, Chiara, additional, Federici, Raffaele, additional, Gallini, Elena, additional, La Porta, Umberto, additional, Ravazzoni, Giulia, additional, Roberti, Maria Federica, additional, Salvi, Marco, additional, Zucchini, Irene, additional, Pelà, Giovanna, additional, and Maggio, Marcello, additional

Published
2020
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35. Interaction of Skeletal and Left Ventricular Mass in Older Adults with Low Muscle Performance

Author

Pelà, Giovanna, primary, Tagliaferri, Sara, additional, Perrino, Felice, additional, Bussolati, Giacomo, additional, Longobucco, Yari, additional, Zerbinati, Luna, additional, Adorni, Elisa, additional, Calvani, Riccardo, additional, Cesari, Matteo, additional, Cherubini, Antonio, additional, Bernabei, Roberto, additional, Di Bari, Mauro, additional, Landi, Francesco, additional, Marzetti, Emanuele, additional, Lauretani, Fulvio, additional, and Maggio, Marcello, additional

Published
2020
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38. The Relationship Between Widespread Pollution Exposure and Oxidized Products of Nucleic Acids in Seminal Plasma and Urine in Males Attending a Fertility Center

Author

Poli, Diana, primary, Andreoli, Roberta, additional, Moscato, Lucia, additional, Pelà, Giovanna, additional, Palma, Giuseppe de, additional, Cavallo, Delia, additional, Petyx, Marta, additional, Pelosi, Giorgio, additional, Corradi, Massimo, additional, and Goldoni, Matteo, additional

Published
2020
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40. Coronavirus Disease 2019: COSeSco – A Risk Assessment Score to Predict the Risk of Pulmonary Sequelae in COVID-19 Patients.

Author

Aiello, Marina, Marchi, Laura, Calzetta, Luigino, Speroni, Silvia, Frizzelli, Annalisa, Ghirardini, Marianna, Celiberti, Valentina, Sverzellati, Nicola, Majori, Maria, Mori, Pier Anselmo, Ranzieri, Silvia, Pisi, Roberta, Pelà, Giovanna, Corradi, Massimo, and Chetta, Alfredo

Subjects
EXPERIMENTAL design, COVID-19, RESEARCH methodology, LUNGS, IDIOPATHIC interstitial pneumonias, RESPIRATORY measurements, FUNCTIONAL assessment, DYSPNEA, HOSPITAL care, COMPUTED tomography, BODY mass index, FIBRIN fibrinogen degradation products
Abstract

Background: The presence of interstitial pneumonia in coronavirus disease 2019 (COVID-19) patients, as diagnosed through laboratory, functional, and radiological data, provides potential predicting factors of pulmonary sequelae. Objectives: The objectives were the creation of a risk assessment score for pulmonary sequelae at high-resolution computed tomography (HRCT) through the assessment of laboratory data, lung function, and radiological changes in patients after the onset of COVID-19 interstitial pneumonia and the identification of predictive factors. Methods: We enrolled 121 subjects hospitalized due to COVID-19 pneumonia in our study. Clinical features, Charlson Comorbidity Index (CCI) score, HRCT score, and blood chemistry data at hospital admission, as well as HRCT score, pulmonary function testing values, exercise capacity by means of a 6-Minute Walk Test (6MWT), and dyspnea perception by the modified Medical Research Council (mMRC) at 4-month follow-up, were all recorded. The variables were elaborated in order to create a predictive model to identify patients at high risk of pulmonary sequelae at HRCT. Results: At the time of follow-up visit, 63% of patients had functional abnormality (diffusion lung capacity and/or total lung capacity <80% of predicted). Age, BMI, CCI, D-dimer, 6MWT, and mMRC were included in the COVID-19 Sequelae Score (COSeSco, ranging 0–15), which was able to individuate COVID-19 patients with radiologic sequelae (HRCT score >10%) at follow-up. The most revelatory COSeSco value that was found to intercept the highest sensitivity (100%) and specificity (77%) was 2. Conclusion: The COSeSco – comprising age, BMI, comorbidities, D-dimer, walking distance, and dyspnea perception – makes it possible to identify particularly at-risk COVID-19 patients who are likely to develop pulmonary sequelae assessed by HRCT. [ABSTRACT FROM AUTHOR]

Published
2022
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44. Interaction of Skeletal and Left Ventricular Mass in Older Adults with Low Muscle Performance.

Author

Pelà, Giovanna, Tagliaferri, Sara, Perrino, Felice, Bussolati, Giacomo, Longobucco, Yari, Zerbinati, Luna, Adorni, Elisa, Calvani, Riccardo, Cesari, Matteo, Cherubini, Antonio, Bernabei, Roberto, Di Bari, Mauro, Landi, Francesco, Marzetti, Emanuele, Lauretani, Fulvio, and Maggio, Marcello

Subjects
*ECHOCARDIOGRAPHY, *FRAIL elderly, *MULTIVARIATE analysis, *BODY movement, *BODY mass index, *SARCOPENIA, *BODY surface area, *LEAN body mass, *SKELETAL muscle, *PHOTON absorptiometry, *LEFT ventricular hypertrophy, *OLD age
Abstract

BACKGROUND: It was recently hypothesized the existence of "cardiac‐skeletal muscle axis." However, the relationship between skeletal muscle mass (SMM) and left ventricular mass (LVM) has never been investigated in the specific group of older individuals with low skeletal mass and physical performance. We tested this hypothesis in the SPRINT‐T (Sarcopenia and Physical Frailty IN older people: multicomponenT Treatment strategies Trial) population using LVM as independent variable and SMM as dependent variable. METHODS: SMM was assessed by dual‐energy X‐ray absorptiometry scan and expressed as appendicular lean mass (ALM), and LVM was estimated through echocardiography. Low ALM was defined according to Foundation for the National Institutes of Health Sarcopenia Project criteria, and Short Physical Performance Battery (SPPB) was used to assess physical performance. RESULTS: The population consisted of 100 persons (33 men and 67 women), aged 70 years or older (mean age = 79 ± 5 years) with low ALM and SPPB ranged between 3 and 9, suggestive of physical frailty. Charlson Comorbidity Index median score was 0. Mean value of LVM was 193 ± 67 g, indexed LVM/body surface area (LVM/BSA) was 112 ± 33 g/m2, and cardiac output (CO) was 65 ± 19 L/min. ALM was strongly and positively correlated with LVM (r = 0.54602; P <.0001), LVM/BSA (r = 0.30761; P <.002), CO (r = 0.49621; P <.0001), body mass index (BMI) (r = 0.52461; P <.0001), sex (r = 0.77; P <.001), fat mass (r = 0.38977; P <.0001), and hemoglobin (Hb) (r = 0.26001; P <.01). In the multivariate analysis, LVM (β =.019 ±.005; P <.0001), CO (β =.038 ±.016; P =.019), BMI (β =.286 ±.051; P <.0001), and Hb (β =.544 ±.175; P =.0025) remained associated to ALM. CONCLUSIONS: In a sample of older persons with low muscle mass and physical performance, LVM was positively and significantly correlated with ALM, independently from blood pressure, physical activity, and other potential confounders. Future studies are needed to address the effect of interventions targeting LVM and SMM. [ABSTRACT FROM AUTHOR]

Published
2021
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50. Calcium channel blockade blunts the renal effects of acute nitric oxide synthase inhibition in healthy humans.

Author

Montanari, Alberto, Lazzeroni, Davide, Pelà, Giovanna, Crocamo, Antonio, Lytvyn, Yuliya, Musiari, Luisa, Cabassi, Aderville, and Cherney, David Z. I.

Abstract

Our aim was to investigate whether blockade of calcium channels (CCs) or angiotensin II type 1 receptors (AT1R) modulates renal responses to nitric oxide synthesis inhibition (NOSI) in humans. Fourteen sodium-replete, healthy volunteers underwent 90-min infusions of 3.0 μg·kg−1·min−1 NG-nitro-l-arginine methyl ester (l-NAME) on 3 occasions, preceded by 3 days of either placebo (PL), 10 mg of manidipine (MANI), or 50 mg of losartan (LOS). At each phase, mean arterial pressure (MAP), glomerular filtration rate (GFR; inulin), renal blood flow (RBF; p-aminohippurate), urinary sodium (UNaV), and 8-isoprostane (U8-iso-PGF2αV; an oxidative stress marker) were measured. With PL + l -NAME, the following changes were observed: +6% MAP (P < 0.005 vs. baseline), −10% GFR, −20% RBF, −49% UNaV (P < 0.001), and +120% U8-iso-PGF2αV (P < 0.01). In contrast, MAP did not increase during LOS + l-NAME or MANI + l-NAME (P > 0.05 vs. baseline), whereas renal changes were the same during LOS + l-NAME vs. PL + l-NAME (ANOVA, P > 0.05). However, during MANI + l-NAME, changes vs. baseline in GFR (−6%), RBF (−12%), and UNaV (−34%) were blunted vs. PL + l-NAME and LOS + l-NAME (P < 0.005), and the rise in U8-iso-PGF2αV was almost abolished (+37%, P > 0.05 vs. baseline; P < 0.01 vs. PL + l-NAME or LOS + l-NAME). We conclude that, since MANI blunted l-NAME-induced renal hemodynamic changes, CCs participate in the renal responses to NOSI in healthy, sodium-replete humans independent of changes in MAP and without the apparent contribution of the AT1R. Because the rise in U8-iso-PGF2αV was essentially prevented during MANI + l-NAME, CC blockade may oppose the renal effects of NOSI in part by counteracting oxidative stress responses to acutely impaired renal NO bioavailability. [ABSTRACT FROM AUTHOR]

Published
2017
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