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14. Magnetic-responsive Pickering emulsions based on MFe2O4 (M = Mn, Fe, Co, Ni, Cu, Zn) for green and efficient oxidation of benzyl alcohol.

Author

Wang, Yan, Wang, Xuan, Dong, Yonghao, Peng, Mingli, Guo, Lina, Cui, Mengyao, He, Yuan, Yi, Jiabao, Ma, Huijun, Zhang, Huan, and Fan, Haiming

Subjects
BENZYL alcohol, COPPER, ALCOHOL oxidation, EMULSIONS, HETEROGENEOUS catalysis, TURNOVER frequency (Catalysis), ORGANIC solvents
Abstract

The selective oxidation of alcohols has drawn significant attention in heterogeneous catalysis with the increasing use of Pickering interfacial catalysis (PIC) for green transformations of alcohols. However, it is still highly desirable to design and develop a solid catalyst with easy separation and recycling, made from abundant resources through a simple synthesis route, for the selective oxidation of alcohols. In this study, ferrite nanoparticles, synthesized via a hydrothermal process, were employed to act as a stabilizer and catalyst in PIC for the oxidation of benzyl alcohol using H2O2. The ferrite nanoparticles exhibited higher catalytic performance in PIC than in acetonitrile. The turnover number (TON) of the nanocatalyst in PIC was found to be 1.5–4 times higher than that in acetonitrile, and the reaction constant in PIC (kPIC = 0.712 h−1) was almost twice that in acetonitrile (kCH3CN = 0.310 h−1) for MnFe2O4 nanoparticles. Moreover, other alcohols could also be oxidized with moderately high conversion and selectivity in PIC. Significantly, the ferrite nanocatalyst could be easily separated from PIC using a magnet for reuse, achieving 88% BzOH conversion after five cycles. The use of hazardous organic solvents was avoided in PIC, making it a more advanced, green and sustainable reaction system. [ABSTRACT FROM AUTHOR]

Published
2024
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15. A potential antiviral role for CCR5+CD8+ T cells in children with hepatitis B.

Author

Tan, Aoxue, He, Yi, Zhou, Yingzhi, Peng, Xiaorong, Chang, Yunan, Peng, Mingli, Ren, Hong, and Xu, Hongmei

Subjects
T cells, HEPATITIS B vaccines, HEPATITIS associated antigen, T-cell exhaustion, ALANINE aminotransferase, HEPATITIS B, CHEMOKINE receptors
Abstract

While dysfunctional exhausted CD8+ T cells hamper viral control when children acquire hepatitis B virus (HBV) infection, it's crucial to recognize that CD8+ T cells have diverse phenotypes and functions. This study explored a subset of CD8+ T cells expressing C‐C chemokine receptor type 5 (CCR5) in children with HBV infection. Thirty‐six patients in the immune tolerant group, 33 patients in the immune active group, 55 patients in the combined response group, and 22 healthy control children were enrolled. The frequency, functional molecules, and effector functions of the CCR5+CD8+ T cell population in different groups were evaluated. The frequency of CCR5+CD8+ T cells correlated positively with the frequency of CCR5+CD4+ T cells and patient age, and it correlated negatively with alanine aminotransferase, aspartate transaminase, HBV DNA, hepatitis B surface antigen, and lactic dehydrogenase levels. CCR5+CD8+ T cells had higher levels of inhibitory and activated receptors and produced higher levels of IFN‐γ, IL‐2, and TNF‐α than CCR5‐CD8+ T cells. CCR5+CD8+ T cells were partially exhausted but possessed a stronger antiviral activity than CCR5‐CD8+ T cells. The identification of this subset increases our understanding of CD8+ T cell functions and serves as a potential immunotherapeutic target for children with HBV infection. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Study of the Cold Curing Characteristics of Isocyanate-Modified Asphalt.

Author

Zhou, Changhong, Peng, Mingli, Yang, Xue, Qi, Yating, and Xu, Bin

Subjects
*ASPHALT, *WATER damage, *GLASS transition temperature, *MOLECULAR dynamics, *VALUE engineering, *CURING
Abstract

Isocyanate esters are widely recognized for their superior curing capabilities. Leveraging this attribute, the current research formulated a modified cold-mixed asphalt blend using 4,4′-methylene diphenyl diisocyanate (MDI). Tests and analyses of the MDI-modified asphalt with varying inclusion percentages of MDI revealed that a mixture containing 15% rock asphalt and 15% MDI-modified asphalt exhibited a more balanced, comprehensive performance. We also conducted an examination of the role and properties of MDI in asphalt modification using molecular dynamics simulations. The cold-curing properties of MDI-modified asphalt as compared to petroleum asphalt were evaluated based on its density, free volume analysis, cohesive energy density, and glass transition temperature. Implementing the LB-13 gradation—a cold-mixed asphalt gradation with a nominal particle size of 13.2 mm recommended by Chinese specifications—we prepared MDI-modified cold-mixed asphalt and carried out analyses of its mechanical characteristics, high-temperature performance, and water damage resistance. The results demonstrated that MDI-modified asphalt showcases excellent ductility, flexibility, and aging resistance, surpassing the performance of petroleum asphalt. The stability, high-temperature rutting, and water damage resistance of the MDI-modified cold-mixed asphalt exceeded the requirements for hot-mixed asphalt. This research provides theoretical and experimental support for isocyanate ester applications in asphalt engineering, presenting significant value for practical engineering applications. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Clinical characteristics and immunogenicity after Omicron breakthrough infection in patients with chronic hepatitis B infection: A longitudinal observational study.

Author

Zha, Guanhua, Chen, Zhiwei, Wu, Na, Huang, Tianquan, Deng, Zhiling, Cai, Dachuan, Peng, Mingli, Hu, Peng, and Ren, Hong

Subjects
BREAKTHROUGH infections, HEPATITIS B, SARS-CoV-2 Omicron variant, IMMUNE response, COVID-19, CHRONIC hepatitis B
Abstract

The clinical and immunological features after breakthrough infection (BTI) during Omicron wave in patients with chronic hepatitis B virus infection (CHB) are still unclear. A total of 101 patients with CHB from our previous coronavirus disease 2019 (COVID‐19) vaccination cohort (NCT05007665), were continued to be followed up at the Second Affiliated Hospital of Chongqing Medical University after BTI, while an additional 39 healthcare workers after BTI were recruited as healthy controls (HCs). Clinical data were collected using questionnaire survey and electronic medical record. Blood samples were used to determine the antibody responses, as well as B and T cell responses. After BTI, the clinical symptoms of COVID‐19 were mild to moderate in patients with CHB, with a median duration of 5 days. Compared with HCs, patients with CHB were more susceptible to develop moderate COVID‐19. The liver function was not significantly damaged, and HBV‐DNA was not activated in patients with CHB after BTI. Patients with CHB could elicit robust antibody responses after BTI (NAbs 13.0‐fold, BA.5 IgG: 24.2‐fold, respectively), which was also significantly higher than that in every period after vaccination (all p < 0.001), and compared to that in HCs after BTI. The CD4+, cTfh, and CD8+ T cell responses were also augmented in patients with CHB after BTI, while exhibiting comparability to those observed in HCs. In patients with CHB after BTI, the immune imprint was observed in B cell responses, rather than in T cell responses. In conclusion, Omicron breakthrough infection induced mild to moderate COVID‐19 symptoms in patients with CHB, without exacerbating the progress of liver diseases. Meanwhile, BTI demonstrated the ability to induce robust antibody and T cell responses in patients with CHB, which was comparable to those observed in HCs. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Safety and Immunogenicity After Primary and Booster Inactivated SARS-Cov-2 Vaccination in Patients with Autoimmune Liver Diseases

Author

Chen, Zhiwei, primary, Wang, Yuting, additional, He, Taiyu, additional, Li, Hu, additional, Ao, Ling, additional, Pan, Qingbo, additional, Zhou, Yingzhi, additional, Zhu, Qian, additional, Xiang, Dejuan, additional, Zhang, Gaoli, additional, Ling, Ning, additional, Chen, Min, additional, Hu, Peng, additional, Peng, Mingli, additional, Cai, Dachuan, additional, Zhang, Dazhi, additional, and Ren, Hong, additional

Published
2023
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24. Dynamic immunogenicity after primary and booster inactivated SARS‐CoV‐2 vaccination in people living with HIV: A longitudinal observational study

Author

Lu, Ting, primary, Chen, Zhiwei, additional, Cao, Yu, additional, Ao, Ling, additional, Li, Zisheng, additional, Gu, Xiaoyi, additional, Ren, Xingqian, additional, Wang, Yixuan, additional, Zhang, Gaoli, additional, Xiang, Dejuan, additional, Chen, Min, additional, Cai, Dachuan, additional, Hu, Peng, additional, Zhang, Dazhi, additional, Peng, Mingli, additional, Shi, Xiaofeng, additional, and Ren, Hong, additional

Published
2023
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26. Humoral responses after primary and booster SARS‐CoV‐2 inactivated vaccination in patients with chronic hepatitis B virus infection: a longitudinal observational study

Author

Chen, Zhiwei, primary, Huang, Tianquan, additional, He, Taiyu, additional, Zha, Guanhua, additional, Zhu, Qian, additional, Zhang, Gaoli, additional, Xiang, Dejuan, additional, Chen, Min, additional, Li, Hu, additional, Ling, Ning, additional, Lan, Yinghua, additional, Xiaofeng, Shi, additional, Zhang, Dazhi, additional, Xu, Pan, additional, Pan, Qingbo, additional, Song, Rui, additional, Cao, Junxiong, additional, Zhang, Yingzhi, additional, Xiang, Hongyan, additional, Feng, Yali, additional, Yang, Ziqiao, additional, Zhang, Biqiong, additional, Shen, Wei, additional, Cai, Dachuan, additional, Peng, Mingli, additional, Hu, Peng, additional, and Ren, Hong, additional

Published
2023
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27. Weakened humoral and cellular immune response to the inactivated COVID-19 vaccines in Chinese individuals with obesity/overweight

Author

Zhu, Qian, primary, Zhang, Yingzhi, additional, Kang, Juan, additional, Chen, Zhiwei, additional, Peng, Mingli, additional, Chen, Min, additional, Zhang, Gaoli, additional, Xiang, Dejuan, additional, Xiao, Shuang, additional, Li, Hu, additional, Mei, Ying, additional, Yang, Jie, additional, Qi, Xiaoya, additional, Cai, Dachuan, additional, and Ren, Hong, additional

Published
2023
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31. Risk of waning humoral responses after inactivated or subunit recombinant SARS‐CoV‐2 vaccination in patients with chronic diseases: Findings from a prospective observational study in China

Author

Li, Hu, primary, Cai, Dachuan, additional, Jiang, Depeng, additional, Li, Xingsheng, additional, Liao, Xiaohui, additional, Liu, Dongfang, additional, Liu, Zuojin, additional, Zhu, Peng, additional, Yin, Guobing, additional, Ming, Jia, additional, Peng, Mingli, additional, Chen, Min, additional, Ling, Ning, additional, Lan, Yinghua, additional, Zhang, Dazhi, additional, Hu, Peng, additional, and Ren, Hong, additional

Published
2023
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32. Additional file 3 of Molecular epidemiology of hepatitis C virus genotypes in different geographical regions of Chinese mainland and a phylogenetic analysis

Author

Tang, Qiao, Chen, Zhiwei, Li, Hu, Zhang, Li, Peng, Mingli, Zeng, Yi, Liu, Xiaoqing, Liu, Zubi, and Hu, Peng

Abstract

Additional file 3: Table S1. The geographical distribution of each subtype in diverse provinces/municipalities. Table S2. The geographical distribution of subtypes used for phylogenic analysis.

Published
2023
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35. A hepatocyte-targeting nanoparticle for enhanced hepatobiliary magnetic resonance imaging

Author

Zhang, Huan, primary, Guo, Yingkun, additional, Jiao, Ju, additional, Qiu, Ying, additional, Miao, Yuqing, additional, He, Yuan, additional, Li, Zhenlin, additional, Xia, Chunchao, additional, Li, Li, additional, Cai, Jing, additional, Xu, Ke, additional, Liu, Xiaoli, additional, Zhang, Ce, additional, Bay, Boon-Huat, additional, Song, Shijie, additional, Yang, Yanlian, additional, Peng, Mingli, additional, Wang, Yaoyu, additional, and Fan, Haiming, additional

Published
2022
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36. Weakened humoral immune responses of inactivated SARS‐CoV‐2 vaccines in patients with solid tumors

Author

Chen, Zhiwei, primary, Zhu, Peng, additional, Liu, Zuojin, additional, Zhu, Bin, additional, Yin, Guobing, additional, Ming, Jia, additional, Song, Rui, additional, Pan, Qingbo, additional, Li, Tong, additional, Jiang, Xingwei, additional, Wang, Bing, additional, Liu, Shuaibin, additional, Cai, Hongxing, additional, Wang, Jingjie, additional, Han, Yuling, additional, Lin, Zijing, additional, Hong, Yang, additional, Chen, Min, additional, Peng, Mingli, additional, Hu, Lina, additional, Cai, Dachuan, additional, and Ren, Hong, additional

Published
2022
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39. Co‐ and Nd‐Codoping‐Induced High Magnetization in Layered MoS2 Crystals.

Author

Ahmed, Sohail, Murmu, Peter P., Sathish, Clastinrusselraj Indirathankam, Guan, Xinwei, Geng, Rex, Bao, Nina, Liu, Rong, Kennedy, John, Ding, Jun, Peng, Mingli, Vinu, Ajayan, and Yi, Jiabao

Subjects
MAGNETIC materials, MAGNETIZATION, ION implantation, MAGNETIC devices, CRYSTALS, RARE earth metal alloys
Abstract

Magnetic 2D‐layered materials are promising for the applications of spintronic devices and compact magnetic devices. There are only a few reported intrinsic 2D‐based magnetic materials. Therefore, introducing magnetic element into 2D‐layered materials is an effective strategy to synthesize 2D‐layered magnetic materials. Recently, ferromagnetism has been realized by doping single transition‐metal or rare‐earth element, whereas, there is no report by codoping of both transition‐metal and rare‐earth elements. Herein, Co and Nd are codoped into MoS2‐layered crystals by ion implantation. An extremely high magnetization of 6916.3 emu cm−3 at 10 K and 80.3 emu cm−3 at 300 K is achieved. The high magnetization is attributed to the contribution from both transition‐metal and rare‐earth elements as well as defects, such as vacancy of cation ions, anions, or interstitials. Hence, herein, a useful strategy may be opened to develop high‐performance magnetic materials based on 2D‐layered materials. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIV

Author

Ao, Ling, primary, Lu, Ting, additional, Cao, Yu, additional, Chen, Zhiwei, additional, Wang, Yuting, additional, Li, Zisheng, additional, Ren, Xingqian, additional, Xu, Pan, additional, Peng, Mingli, additional, Chen, Min, additional, Zhang, Gaoli, additional, Xiang, Dejuan, additional, Cai, Dachuan, additional, Hu, Peng, additional, Shi, Xiaofeng, additional, Zhang, Dazhi, additional, and Ren, Hong, additional

Published
2022
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45. Safety and antibody response to inactivated COVID‐19 vaccine in patients with chronic hepatitis B virus infection

Author

He, Taiyu, primary, Zhou, Yingzhi, additional, Xu, Pan, additional, Ling, Ning, additional, Chen, Min, additional, Huang, Tianquan, additional, Zhang, Biqiong, additional, Yang, Ziqiao, additional, Ao, Ling, additional, Li, Hu, additional, Chen, Zhiwei, additional, Zhang, Dazhi, additional, Shi, Xiaofeng, additional, Lei, Yu, additional, Wang, Zhiyi, additional, Zeng, Weiqun, additional, Hu, Peng, additional, Lan, Yinghua, additional, Zhou, Zhi, additional, Kang, Juan, additional, Huang, Ying, additional, Shi, Tongdong, additional, Pan, Qingbo, additional, Zhu, Qian, additional, Ran, Xiping, additional, Zhang, Yingzhi, additional, Song, Rui, additional, Xiang, Dejuan, additional, Xiao, Shuang, additional, Zhang, Gaoli, additional, Shen, Wei, additional, Peng, Mingli, additional, Cai, Dachuan, additional, and Ren, Hong, additional

Published
2022
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