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Although locomotive syndrome (LS) is a condition of reduced mobility, little information is available regarding the loss of site-specific skeletal muscle mass. The aim of the present study is to examine site-specific muscle loss in elderly males with LS. A total of 100 men ranging in age from 65 to 74 years were divided into two groups (LS and non-LS) using LS risk tests including the stand-up test, two-step test, and the 25-question geriatric locomotive function scale Muscle thickness (MTH) at eight sites—anterior and posterior thigh (AT and PT, respectively), anterior and posterior lower leg (AL and PL, respectively), rectus abdominis (RA), anterior and posterior upper arm (AU and PU, respectively), and anterior forearm (AF)—was evaluated using B-mode ultrasound. Furthermore, the 30-s chair stand test (CS-30), 10-m walking time, zig-zag walking time, and sit-up test were assessed as physical functions. There were no significant differences in age and body mass index between the LS and non-LS groups. The percentage of skeletal muscle was lower in the LS group than in the non-LS group. Although there were no differences in the MTH of AU, PU, AF, PT, Al and PL, site-specific muscle loss was observed at RA and AT in the LS group. CS-30, 10-m walking time, zig-zag walking time, and sit-up test in the LS group were all worse than those in the non-LS group. The MTHs of RA and AT were both correlated to those physical functions. In conclusion, the LS group had site-specific muscle loss and worse physical functions. This study suggests that site-specific changes may be associated with age-related physical functions. These results may suggest what the essential characteristics of LS are.

COVID-19-associated lockdown has been implemented worldwide, potentially causing unfavorable changes in lifestyle and psychological health. Physical literacy, healthy diets, and lifestyles play important roles in mitigating the adverse effects. Therefore, this study aimed to enable individuals to understand their fitness literacy and establish a personalized exercise plan. In this study, 903 adults aged 19－59 were surveyed based on the concept of scientific fitness literacy and the influencing factors in the context of the effective containment of COVID-19 before (2019) and during (2020) the pandemic. This study screened four factors from four dimensions–cognition, attitude, ability and skills, and behavior and habits–that can influence adults' scientific fitness literacy. Confirmatory factor analysis (CFA) and AMOS software were used to construct an evaluation index system of scientific fitness literacy for adults. The model consisting 10 items with 4 factors to evaluation index system has good overall fitness, reliability, convergent validity, differential validity, and model stability and was able to analyze the factors that affect the scientific fitness literacy of individuals from different perspectives. This allowed individuals at different stages to have a deeper understanding of scientific fitness literacy.

There are a large number of 6.97 million left-behind children in China at the end of August 2018. Left-behind children exhibit many psychologically unhealthy behavioural disorders. This study aimed to compare the differences in scientific fitness literacy (SFL) between rural left-behind and general minors, and to analyze the factors affecting the SFL of left-behind minors in the family environment. A random stratified sampling was conducted among minors aged 3–18 in rural areas of China, and 2239 valid samples were obtained. The questionnaire is based on the SFL part and the family environment part of the China National Fitness Activity Status Survey, except for the SFL part of the children’s questionnaire does not contain the attitude dimension, the questionnaires of several other age groups contain three dimensions: attitude, skills, and habits. The SFL of general children and adolescents was higher than that of left-behind children and adolescents, and in the sub-dimensions, children’s attitudes and adolescents’ skills and habits differed greatly, with the general minors having better performance. The SFL showed a significant increasing trend with age in the general minors but the difference between children and adolescents in the left-behind minors was not significant. The scores of habituation in left-behind minors increased with age group, and the scores of the general minors group did not vary much between age groups. In the multiple regression analysis for the left-behind minors, it was found that left-behind young children were less influenced by family environment on SFL score, and children’s SFL was more influenced by family environment. A separate analysis of the 7–9 and 10–12-year-old groups revealed that factors such as parental support and encouragement influenced SFL with different weights, and the importance of parents rotated, while the number of sporting goods in the family was important in all four age models. For the left-behind minors with a large amount in China, the role of the family environment in their SFL cannot be ignored, and the promotion of this literacy should be carried out in a targeted manner.

Background：Physical activity (PA) is likely to be the most important modifiable factor in skeletal muscle development. However, the influence of PA on skeletal muscle of preschool children has not been thoroughly investigated. The main objective of this study is to objectively measure PA) and then evaluate the association between site-specific muscle changes and PA in relation to sex and weight statusin preschool children aged 3 to 4 years. Methods: A total of 86 healthy preschool children, aged 3-4 years, were instructed to wear an accelerometer for seven consecutive days. The number of steps taken daily and minutes spent in moderate-to-vigorous PA (MVPA) and total PA (TPA) were recorded. Muscle thickness was measured by B-mode ultrasonography using a 5-18 MHz scanning head. muscle thickness was measured at seven sites: the lateral forearm, upper arm, abdomen, anterior and posterior thigh, anterior and posterior lower leg. Results: There was no significant difference between boys and girls in terms of MVPA and TPA on weekdays and weekends. According to the linear regression models, after adjusting for daylight duration, the muscle of the posterior thigh was significantly positively associated (p < 0.05) with daily steps and MVPA on weekdays for boys and girls, respectively. Conclusions: We found that the muscle thickness of the posterior thigh in preschool children was significantly positively associated with PA, as measured by daily steps and MVPA. We suggest that for the overall health and wellbeing of preschool children, levels of PA should be maintained and/or increased, and preferably transformed into a regular part of daily living.

Background Resistance training has been recommended as an effective measure against age-related loss of muscle mass and muscle strength, called sarcopenia, even in older adults. However, despite subjecting each participant to the same training program, the training effect solely depended on the individual. This study aimed to evaluate whether certain blood parameters influenced the effect of a low-load resistance training program on muscle thickness in the community-dwelling elderly population. Methods Sixty-nine community-dwelling Japanese (49 women and 20 men) subjects aged 69.4 ± 6.5 years were included. Low-load resistance training was performed twice a week for 12 weeks. Muscle thickness at the anterior aspects of the thigh (AT) was measured using a B-mode ultrasound device, and 22 blood parameter levels were assessed before and after the program. We checked the first quartile value of each parameter to establish cutoff values, and participants were divided into low or normal groups for each parameter. Results A low-load resistance training program significantly increased muscle thickness at the AT. The interaction between time and groups was examined at low ( Conclusions Serum Alb level may act as a biomarker to predict the effects of low-load resistance training programs on muscle hypertrophy in elderly individuals. Trial registration This study was retrospectively registered in UMIN-Clinical Trial Registry (CTR), ID: UMIN000042759 (date of registration, 14 Dec 2020).

Children's and adolescents' participation in soccer is low in all regions of China. To achieve coordinated development of soccer in all regions and contribute to a strong sports nation, this study aims to identify the factors that influence the participation of children and adolescents in soccer programs through a cross-sectional analysis of the "soccer population" of children and adolescents aged 7–18. A total of 38,258 children and adolescents aged 7–18 completed a questionnaire; children in the 7–9 age group were helped by their primary guardians. The questions concerned the family level, school level, community level, and individual level. The results showed that the area of the region and the average annual precipitation were correlated with the participation of children and adolescents in soccer programs. In addition, the percentage of children and adolescents participating in soccer programs was higher than the percentage of those who liked it and were proficient in it. Parental encouragement and support, as well as easy access, availability, and safety of sports facilities, are likely to promote children's and adolescents' participation in soccer programs.

Scientific fitness literacy (SFL) is a holistic concept based on physical literacy but has a smaller scope and is more specific to exercise and scientific fitness. We developed an instrument to assess SFL and explored the differences and similarities in the effects of the home environment on children’s SFL. Data from a nationwide stratified random sample of children were analyzed using multiple linear regression. SFL scores were significantly lower for preschoolers than for school-age children. The family environment has an impact throughout the preschool and school years, with school-age children’s SFL being less influenced by family members than preschool children; screen time has a negative impact on their SFL but reducing the number of electronic devices and increasing parental physical activity and modeling can alleviate its impact. The economic status of the family is crucial, with sports consumption expenditure and household sports equipment ownership being favourable factors for children’s SFL. Positive parental attitudes and sporting habits have a positive impact on their children’s SFL. The findings of this study can be used to improve children’s SFL in the home environment and to take effective measures to avoid the risk factors.

This study aimed to evaluate the association between locomotive syndrome (LS) and daily physical activity (PA) in community-dwelling older adults. This cross-sectional study included 80 healthy Japanese older adults (40 men and 40 women; age: 60–79 years). Habitual daily PA was evaluated using a triaxial wrist accelerometer. Participants were divided into two groups based on the results of the two-step test, stand-up test, and 25-question geriatric locomotive function scale. Binomial logistic regression analysis was conducted to examine the statistical relationships between daily PA and category of LS, adjusting for age from adjusted odds ratio (adjusted OR) with the 95 percent confidence intervals (95%CI) and bootstrap 95%CI. The mean step count and time spent on moderate to vigorous physical activity (MVPA) were significantly higher among non-LS participants than among LS participants in women, but not in men. Logistic regression analyses indicated that spending longer than 28 min/day on MVPA was significantly associated with a lower likelihood of LS relative to short time category under 28 min/day in women (adjusted OR = 0.12, 95%CI = 0.02–0.59, bootstrap 95%CI = 0.01–0.43), but not in men. This study suggests that in community-dwelling older women, those with higher MVPA had lower odds of LS, and daily MVPA was associated with LS, but not in men. Therefore, the associations between LS and daily physical activity were partly dependent on sex differences.

This study aimed to clarify whether low-load resistance training at a low frequency (twice a week) using body weight and elastic band improves muscle size, muscle strength, and physical functions and to compare the training effects between supervised training and a combination of supervised and unsupervised training in untrained older adults. Fifty-one older adults (ages: 57-75 years) selected to either a supervised (S) training group (n = 34) or a combined supervised and unsupervised (SU) group (n = 17). Both groups performed low-load resistance training composed of nine exercises for 12 weeks. The S group participated in supervised exercise sessions twice a week, and the SU group performed a supervised exercise session once a week and an unsupervised exercise session at home also once a week. For muscle thicknesses in the anterior aspects of the forearm, upper arm, and thigh and the posterior aspect of the thigh, group × time interactions were observed (p < 0.05). The hypertrophic effects were higher in the S group. Isometric knee extension strength and physical functions increased similarly in both groups. Low-load resistance training using body weight and elastic band twice a week for 12 weeks induces muscle hypertrophy and increases muscle strength and physical functions in older adults. Although the muscle hypertrophic effects are greater in the S group than in the SU group, the other effects were similar between the groups.

The previous results from cross-sectional studies indicate that there could be alterations across time in handgrip strength (HGS) asymmetry. One way to investigate this is to test the same children multiple times. Therefore, we aimed to evaluate the laterality of HGS in healthy young children at two different time points separated by a year.A total of 165 preschool children (79 males and 87 females) between the ages of 4.5 and 5.6 years participated and performed maximal voluntary HGS in both hands using a Smedley handgrip dynamometer. We ran a paired sample t-test on the difference scores (right - left vs. right - left) to determine if HGS (right vs. left) differed across time.The difference between hands (t = -4.804, p .0001) did differ between time points. At the initial test, the mean value of the HGS in the right hand was approximately 15% higher than that of the left hand. This difference between hands was reduced following a year. The mean bias between tests (second test - initial test) and the 95% limits of agreement was -0.84 (-5.27, 3.58) kg.Contrary to our hypothesis, HGS asymmetry during the initial test (at age 5) was not observed in the second test completed a year later (at age 6). These results suggest that HGS asymmetry is uncertain in children between 5 and 6 years. In this short-term study, it was impossible to ascertain when HGS asymmetry first appeared. Longer term studies are required to better determine when these changes occur.

Background: Locomotive syndrome (LS) is associated with weakness and loss of function in the musculoskeletal organs. To evaluate the association between LS and daily physical activities (PA) in community-dwelling older adults using a three-axis accelerometer. Methods: This cross-sectional study included healthy 80 older adults (40 men and 40 women; age: 60-79 years). Three functional tests, the two-step test, the stand-up test, and the 25-question geriatric locomotive function scale (GLFS) were used to assess the risk of LS. Maximal isometric muscle strengths of the knee extensors were examined, and the weight bearing index (knee extension strength/body weight) was calculated. Habitual daily PA was evaluated using a three-axis wrist accelerometer. Results: Of the 80 participants, 41 (51.3%) fulfilled the diagnostic criteria for LS (including a two-step test score < 1.3, difficulty with one-leg standing from 40 cm in the stand-up test, and a 25-question GLFS score ≥ 7) We found that step count and time spent performing moderate to vigorous PA (MVPA) were significantly higher in women participants without LS compared to those with LS (p = 0.01); no significant difference was found in men. Logistic regression analyses indicated a longer time spent performing MVPA (> 47.26 min/day) was associated with a lower risk of LS compared to only performing for 21.11 min/day. Conclusions: Our data showed that daily MVPA using a three-axis accelerometer was associated with LS in community-dwelling older adult women, but not in men.

The purpose of the present study was to investigate the effect of the progressive walking program on lower limb muscle size and strength and evaluated whether the stair-climbing exercise provided additional training effects when combined with the walking program. Fifteen elderly subjects (age 69 ± 1 years, height 1.63 ± 0.02 m, body weight 64.5 ± 2.0 kg) were randomly assigned to a walking group or a walking and stair-climbing group. The progressive walking program comprised continuous (week 1-8) and interval (week 9-17) exercises. The walking and stair-climbing group also performed stair climbing. Muscle thickness, strength, and walking performance were evaluated before and 8 and 17 weeks after the start of the program. The muscle thickness of the anterior and posterior parts of the thigh significantly (p < 0.05) increased in both groups. There was also a significant (p < 0.01) main effect of time in isometric maximal strength and the values expressed relative to body mass for both knee extension and flexion. However, no group × time interactions were noted. Furthermore, the percentage change of knee flexion strength after the training period was significantly (p < 0.01) correlated with the pre-intervention value. Seventeen weeks of the progressive walking program can increase thigh muscle size and strength for older adults; however, an added stair-climbing exercise may not provide additional training effects. Furthermore, the magnitude of improvement in knee flexion strength would depend on the pre-intervention value.

Glufosinate-ammonium, a widely used chiral herbicide, has become the focus of attention because of its toxicity toward non-target organisms and its degradation behavior in the environment. With the introduction of L-glufosinate-ammonium products, the toxicity and environmental behavior of rac-glufosinate-ammonium and L-glufosinate-ammonium have become the subject of increasing interest. The overall goal of this study was to investigate the differences in toxicity and biodegradation of rac-glufosinate-ammonium and L-glufosinate-ammonium in an aquatic organism, Scenedesmus obliquus. The toxicity of rac-glufosinate-ammonium and L-glufosinate-ammonium to S. obliquus was compared by measuring EC

Background Low muscle strength has been focused on as an essential characteristic of sarcopenia, and the 30-s chair stand test (CS-30) could be a particularly useful test for assessing muscle strength. While it is speculated to be a beneficial tool for the assessment of sarcopenia, this remains to be verified. In this study, we examined the reliability and optimal diagnostic score of the CS-30 for assessing sarcopenia in elderly Japanese participants. Methods This cross-sectional study included 678 participants (443 females and 235 males) who underwent the test for sarcopenia as per the Asian Working Group for Sarcopenia (AWGS) 2019, the CS-30 test, and the isometric knee-extension muscle strength test. ROC analysis was used to estimate the optimal CS-30 scores at which sarcopenia was detected. Results CS-30 scores were positively associated with sarcopenia (OR: 0.88; 95% CI:0.82–0.93). The AUC of the CS-30 for sarcopenia definition were 0.84 (p p Conclusions The CS-30 was found to be a reliable test for sarcopenia screening in the elderly Japanese population.

Background Resistance training has been recommended as an effective measure against age-related loss of muscle mass and muscle strength, called sarcopenia, even in older adults. However, despite subjecting each participant to the same training program, the training effect solely depended on the individual. This study aimed to evaluate whether certain blood parameters influenced the effect of a low-load resistance training program on muscle thickness in the community-dwelling elderly population.Methods Sixty-nine community-dwelling Japanese (49 women and 20 men) subjects aged 69.4±6.5 years were included. Low-load resistance training was performed twice a week for 12 weeks. Muscle thickness at the anterior aspects of the thigh (AT) was measured using a B-mode ultrasound device, and 22 blood parameter levels were assessed before and after the program. We checked the first quartile value of each parameter to establish cutoff values, and participants were divided into low or normal groups for each parameter.Results A low-load resistance training program significantly increased muscle thickness at the AT. The interaction between time and groups was examined at low (Conclusions Serum Alb level may act as a biomarker to predict the effects of low-load resistance training programs on muscle hypertrophy in elderly individuals.Trial registration This study was retrospectively registered in UMIN-Clinical Trial Registry (CTR), ID: UMIN000042759. Date of registration: 14/12/2020.

[Purpose] This study aimed to identify the efficacy of a progressive walking program on the risk of developing locomotive syndrome among untrained elderly Japanese people. [Participants and Methods] Twenty-four untrained elderly individuals (68 ± 4 years) completed a 17-week progressive walking program. The stand-up, two-step tests and the 25-question geriatric locomotive function scale were used to assess the risk of locomotive syndrome at baseline, the 8-week midpoint (2 months), and the 17-week endpoint (4 months). Maximal isometric muscle strength of the knee extensors and flexors were measured using a dynamometer with the hip joint angle at 90° of flexion and physical function (the 30-s sit-to-stand, sit-up, 10-meter walk, and grip strength) were evaluated. [Results] The 4-month walking program significantly improved the two-step test and geriatric locomotive function scale scores. This may be attributable to the improvement in knee flexor strength and physical function. [Conclusion] A 4-month program of progressive walking effectively lowered the risk of developing locomotive syndrome in elderly Japanese people by improving knee flexor muscle strength and physical function.

It is unclear whether the measurement of maximum muscle strength in younger children can be performed accurately due to factors such as motivation and maturity (i.e., the ability to receive instruction). If there is a large change in a ratio between muscular strength and size from the youngest to the oldest, then this might provide some indication that the youngest may not have been able to voluntarily activate their muscles for reasons mentioned previously. The purpose of this study was to observe the ratio between handgrip strength (HGS) and forearm muscle thickness (MT) across differing ages in younger children. A total of 1133 preschool children (559 boys and 574 girls) between the ages of 4.5 and 6.5 years had MT and HGS measurements and calculated the ratio of HGS/MT (kg/cm). Linear regression was used to assess the impact of age and sex on the dependent variables of MT, HGS, and the HGS/MT ratio. The HGS/MT ratio increases moderately from age 4.5 to 6.5 in both boys and girls. However, the difference in this ratio was small between the age ranges in this sample. Our results indicate children as young as 4.5 may be accurately measured with the handgrip strength test.