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11. Context matters: using an Evidence to Decision (EtD) framework to develop and encourage uptake of opioid deprescribing guideline recommendations at the point-of-care

Author

Langford, Aili V., Bero, Lisa, Lin, Chung-Wei Christine, Blyth, Fiona M., Doctor, Jason N., Holliday, Simon, Jeon, Yun-Hee, Moullin, Joanna C., Murnion, Bridin, Nielsen, Suzanne, Penm, Jonathan, Reeve, Emily, Reid, Sharon, Wale, Janet, Osman, Rawa, Gnjidic, Danijela, and Schneider, Carl R.

Published
2024
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17. LInezolid Monitoring to MInimise Toxicity (LIMMIT1): A multicentre retrospective review of patients receiving linezolid therapy and the impact of therapeutic drug monitoring

Author

Lau, Cindy, Marriott, Deborah, Bui, Jessica, Figtree, Melanie, Gould, Michael, Chubaty, Adriana, Su, Yuen, Adhikari, Suman, Konecny, Pam, Kozierowski, Kristi, Holland, Taylor, Milliken, Eliza, Akram, Ayesha, Mcnamara, Alexander, Sun, Yihui, Van Hal, Sebastiaan, Patanwala, Asad E, Shahabi-Sirjani, Aryan, Gray, Timothy, Yeo, Chin Yen, Netluch, Angela, Halena, Stephanie, Appay, Marcelle, Alameddine, Rozanna, Yin, Fiona, Nguyen, Quoc, So, Mei-Yi, Sandaradura, Indy, Kim, Hannah Yejin, Galimam, Semun, Cerruto, Nicole, Lai, Tony, Gilbey, Timothy, Daveson, Kathryn, Reuter, Stephanie E, Penm, Jonathan, and Alffenaar, Jan-Willem

Published
2023
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26. Association between self‐reported pain experiences in hospital and ratings of care, readmission and emergency department visits: a population‐based study from New South Wales, Australia.

Author

Prasad, Narisha, Penm, Jonathan, Watson, Diane E., Tran, Bich N. H., Dai, Zhaoli, and Tan, Edwin C. K.

Subjects
*EMERGENCY room visits, *PATIENTS' attitudes, *TORRES Strait Islanders, *RATINGS of hospitals, *PATIENT experience
Abstract

Summary Introduction Methods Results Discussion Evidence on patient experiences with pain in hospitals and its impact on post‐discharge outcomes is limited. This study investigated the prevalence of pain in hospitals, patient characteristics associated with pain management adequacy, and the link between pain experiences, care ratings, readmission and emergency department visits after discharge.We conducted a retrospective cross‐sectional analysis of the 2019 Adult Admitted Patient Survey, focusing on self‐reported pain experiences, including presence, severity and management adequacy. The outcomes included self‐reported overall care ratings; readmission; and emergency department visits within one month of discharge. Multivariable logistic regression adjusted for population weight was used to estimate adjusted odds ratios.Among 75 large public hospitals, 21,900 patients responded (35% response rate), with 51% of patients reporting pain (mean (SD) age 57 (8.8) y; 54.9% female), 38.3% of whom classified their pain as severe. Aboriginal and/or Torres Strait Islander people and patients who spoke a language other than English were less likely to report adequate pain management (aOR (95%CI) 0.74 (0.58–0.96) and 0.82 (0.70–0.96), respectively). Pain also correlated with poor to very poor care ratings (aOR (95%CI) 2.05 (1.42–2.95)). Those patients who experienced pain were twice as likely to be readmitted (aOR (95%CI) 1.92 (1.55–2.37)) or visit the emergency department after discharge (aOR (95%CI) 1.91 (1.58–2.32)). Conversely, adequate pain management was associated with a lower likelihood of readmission (aOR (95%CI) 0.69 (0.51–0.94)) and emergency department visits (aOR (95%CI) 0.62 (0.44–0.87)). Mediation analysis suggests adequate pain management significantly mediated the relationship between pain severity and hospital rating (50.8%), readmission (11.6%) and emergency department visits (5.9%), after adjusting for all available observed confounders.This study highlights the importance of adequate pain management in patients' perception of care and recovery outcomes, especially among culturally and linguistically diverse patients. [ABSTRACT FROM AUTHOR]

Published
2024
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27. A pilot multicentre randomised clinical trial to determine the effect of a pharmacist‐partnered opioid tapering intervention before total hip or knee arthroplasty.

Author

Liu, Shania, Patanwala, Asad E., Stevens, Jennifer, Penm, Jonathan, Naylor, Justine, Adie, S., Archer, A., Brady, B., Byrnes, T., Descallar, J., Eastment, C., Fung, M., Genel, F., Hassett, G., Hui, C. F., Jansson, A. G., Keehan, M., Luckie, K., Mayze, E., and Morgan, E.

Subjects
TOTAL hip replacement, TOTAL knee replacement, GENERAL practitioners, PATIENT compliance, OPIOID analgesics
Abstract

Summary: Background: Opioid analgesic use before total hip or knee arthroplasty has been associated with worse postoperative outcomes. This pilot study aimed to examine the feasibility of a telehealth‐based pharmacist‐partnered opioid tapering intervention before elective primary hip or knee arthroplasty and its potential effectiveness compared with usual care. Methods: This study was conducted at seven hospitals in New South Wales, Australia. Eligible patients were those aged ≥ 18 years, scheduled to undergo primary hip or knee arthroplasty for osteoarthritis and taking opioid analgesics pre‐operatively. The intervention group participated in an opioid tapering telehealth service, a partnership between a pharmacist and general practitioner, for 3 months pre‐operatively up to the day of surgery, while the control group received usual care. The primary outcomes of the study were to investigate the feasibility of the intervention (i.e. adherence to treatment) and potential effectiveness in decreasing baseline daily opioid dose by > 50% before surgery. Results: Between December 2021 and June 2023, 70 patients were recruited and assigned randomly to the intervention group (n = 35) or control group (n = 35). Baseline characteristics were similar between groups. Thirty patients in each group completed their allocated treatment. All patients allocated to the intervention group completed at least one appointment with a pharmacist, with the median (IQR [range]) being 2 (1–4 [1–6]) appointments. The number of patients who successfully decreased their baseline daily opioid dose by ≥ 50% before surgery was 27/30 in the intervention group compared with 5/30 in the usual care group (p < 0.001). Conclusions: The findings of this pilot study support the feasibility of a telehealth‐delivered, pharmacist‐partnered opioid tapering service for patients scheduled for primary hip or knee arthroplasty. A broader multicentre study to examine the effectiveness of this intervention on clinical outcomes is warranted. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Surface contamination of cytotoxic medicine in preparation and patient care areas in Australian hospitals: a retrospective cross‐sectional study

Author

Woodward, Vincent, primary, Panjarjian, Meghrie, additional, Devi, Devika, additional, Hanrahan, Jane, additional, Soriano, Michael, additional, Roper, Matt, additional, Musa, Hala, additional, Davies, Stephanie, additional, Samios, Peter, additional, Teh, Michael, additional, Barclay, Peter, additional, Naughtin, Clare, additional, Vaillancourt, Régis, additional, Nikolaidis, Carl, additional, Pelland, Bryan, additional, and Penm, Jonathan, additional

Published
2024
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36. Standard of practice in pain management for pharmacy services

Author

Liu, Shania, primary, Bui, Thuy, additional, Lee, Kenny Kwon Ho, additional, Lim, Wei Sheng Arthur, additional, Lim, Daniel, additional, Onishko, Christine, additional, Penm, Jonathan, additional, Tran, Chi, additional, Tuffin, Penelope, additional, and Mellor, Yee, additional

Published
2024
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