131 results on '"Pepe, R"'
Search Results
2. New autochthonous vines of Campania under evaluation for inclusion in productive sector
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Caputo A.R., Alba V., Bergamini C., Gasparro M., Masi G., Tarricone L., Crupi P., Roccotelli S., Pepe R., and Del Lungo S.
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Microbiology ,QR1-502 ,Physiology ,QP1-981 ,Zoology ,QL1-991 - Abstract
The drastic reduction of agrobiodiversity has induced all countries in the world to implement numerous initiatives to safeguard genetic resources. The biodiversity issue is also one of the priority objectives of the global action plan for the conservation and sustainable use of FAO's cytogenetic resources and of the International Treaty on Plant Genetic Resources for Food and Agriculture. In Italy, the primary competence on genetic resources of agricultural interest is entrusted to the Ministry of Agricultural. In 2004, the Ministry entrusted the coordination of the RGV/FAO Project to CREA. The main objectives of the project, in addition to the inventory of accessions present in the collections of the structures involved, are their morphological, agronomic and molecular characterization and the productive enhancement with particular reference to the autochthonous varieties at risk of extinction. The project in question includes the activities of recovery and characterization of the viticultural germplasm illustrated in the present work. The 12 vines described here, like others yet to be rediscovered, are strongly linked to small winegrowers and indissolubly characterial of a territory in Campania Region that from the socio-cultural (rather fragmented agricultural system) and environmental orography point of view, like the national one, is very diversified.
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- 2019
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3. DECREASED LOW-DENSITY GRANULOCYTES AS POSSIBLE DIAGNOSTIC MARKERS OF MYELODYSPLASTIC SYNDROMES WITH EXCESS OF BLASTS
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Giudice, V, Ferrara, I, Gorrese, M, Bertolini, A, Pepe, R, D'Alto, F, Manzo, P, D'Addona, M, Martorelli, Mc, Langella, M, Cuffa, B, Serio, B, and Selleri, C
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- 2022
4. The Incidence of Atypical Refluxes in Varicose Veins: Instrumental Pre-Operative Study
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Pepe, R., Marchitelli, E., Gloria, R., Guazzaroni, M., Pocek, M., Romagnoli, A., Simonetti, G., Negus, David, editor, Jantet, Georges, editor, and Coleridge-Smith, Philip D., editor
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- 1995
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5. Non-destructive evaluation of resistance projection welded joints (RPW) by flash thermography
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Dell’Avvocato, G., primary, Palumbo, D., additional, Pepe, R., additional, and Galietti, U., additional
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- 2021
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6. Combined Radiation and Oncolytic Viral Therapy Augments Cytotoxic and Immunogenic Antitumor Effects Against Melanoma
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Wang, S.J., primary, Jhawar, S.R., additional, Bommareddy, P., additional, Thandoni, A., additional, Aspromonte, S., additional, Pepe, R., additional, Schiff, D.S., additional, Kaufman, H.L., additional, Goyal, S., additional, Goydos, J., additional, Haffty, B.G., additional, Silk, A.W., additional, and Zloza, A., additional
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- 2018
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7. New autochthonous vines of Campania under evaluation for inclusion in productive sector.
- Author
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Roca, P., Caputo, A.R., Alba, V., Bergamini, C., Gasparro, M., Masi, G., Tarricone, L., Crupi, P., Roccotelli, S., Pepe, R., and Del Lungo, S.
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- 2019
- Full Text
- View/download PDF
8. Cardiac Tamponade and Splenic Littoral Cell Angioma: An Unusual Presentation of a Very Rare Disease
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Di Santo M, Schiavone C, Mucilli F, Pepe R, and Rossi S
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Pathology ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Splenectomy ,medicine.disease ,Splenic tumor ,03 medical and health sciences ,0302 clinical medicine ,Pathognomonic ,Littoral cell angioma ,030220 oncology & carcinogenesis ,Cardiac tamponade ,Medicine ,030212 general & internal medicine ,Splenic disease ,Presentation (obstetrics) ,business ,Rare disease - Abstract
Littoral cell angioma (LCA) is a rare benign vascular splenic tumor that can evolve, potentially, into a malignant form. It can be found incidentally in the majority of cases during ultrasound (US) or other imaging exams, performed for other problems. It has not a (US) or computed tomography (CT) pathognomonic pattern so diagnosis is made by histological and immunochemical analysis. This is a case of LCA discovered incidentally in an 81-year-old woman admitted to our hospital for dyspnea due to cardiac tamponade. The splenic disease was discovered during an US abdomen study performed to reveal a source of infection. Our patient was evaluated also with CT study that confirmed the presence of splenic lesions but could not make a diagnosis. The patient underwent a splenectomy that showed histological and immunochemical evaluations consistent with presence of LCA.
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- 2016
9. I legumi nella biodiversità mediterranea
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LAGHETTI G, PIERGIOVANNI AR, LIOI L., PEPE R, and ZACCARDELLI M
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germoplasma ,biodiversità ,legumi - Abstract
La salvaguardia e gestione in maniera sostenibile delle biorisorse nei settori agrario, alimentare, ambientale e della tutela della salute, insieme all'aumento delle conoscenze di biologia di base sono gli obiettivi istituzionali dell'Istituto di Bioscienze e Biorisorse del CNR di Bari. Il nucleo di questa attività è rappresentato dalla banca del germoplasma che dal 1970 custodisce oltre 65.000 accessioni di 524 specie di piante agrarie di interesse mediterraneo, 73 delle quali appartengono alle leguminose. Negli ultimi due decenni l'IBBR ha partecipato e coordinato numerosi progetti di ricerca, finalizzati al reperimento, caratterizzazione e promozione di centinaia di ecotipi italiani di leguminose. Queste attività sono state condotte in collaborazione con diverse Università, Istituti del CREA, assessorati regionali all'agricoltura, provincie, comuni e associazioni di agricoltori. Le ricerche svolte hanno consentito di definire le caratteristiche agronomiche, genetiche e nutrizionali degli ecotipi studiati. Inoltre, l'IBBR ha supportato da un punto di vista scientifico l'iter burocratico per l'ottenimento di marchi comunitari (IGP e DOP) e non (es. marchio De.C.O.) o l'iscrizione al registro dei prodotti tipici regionali per alcuni ecotipi di particolare pregio. A titolo di esempio dell'attività svolta sono presentati i risultati ottenuti in collaborazione col CREA-ORT di Pontecagnano, con l'ALSIA A.A.S.S.D. 'Pollino' di Rotonda (PZ), e quelli del progetto PSR "SaVeGRaINPuglia" attualmente in corso, che vede l'IBBR impegnato nel ruolo di capofila. La Campania è una delle regioni più ricche di biodiversità vegetale. Con la Misura 214 del PSR 2007-2013, sono stati finanziati due importanti progetti, Agrigenet e Salve, che hanno coinvolto Istituzioni universitarie e di ricerca (CREA, CNR) campane. Queste Istituzioni si sono impegnate nella caratterizzazione agronomica, morfo-fisiologica, biochimica, chimico-nutrizionale, organolettica e molecolare, di un elevato numero di varietà locali campane di ortive, fruttiferi e vitigni. Tra i legumi, sono stati caratterizzati 16 ecotipi di fagiolo, 9 di cicerchia, 7 di cece e 2 di lenticchia. Le caratterizzazioni eseguite ai vari livelli sopra menzionati, hanno consentito di confermare o individuare diversi legumi locali sicuramente degni di essere inseriti in percorsi di valorizzazione dei prodotti tipici, per i quali la Regione Campania sta molto investendo, al fine di creare opportunità di reddito e di presidio degli areali interni svantaggiati.
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- 2016
10. Utilizzo della Cardio TC per la formulazione del giudizio d'idoneità in lavoratori turnisti sottoposti a by-pass coronarico addetti alla movimentazione manuale dei carichi
- Author
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CORVINO F, MERCADANTE I, PEPE R, CRISPINO V, LAMBERTI, Monica, Corvino, F, Mercadante, I, Pepe, R, Crispino, V, and Lamberti, Monica
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- 2011
11. Incidenza e significato clinico del blocco di branca sinistra nella valutazione cardiovascolare di lavoratori sottoposti a movimentazione manuale di carichi
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SPACONE D, LAMBERTI, Monica, DE ROSA R, RATTI G, TEDESCHI C, CAPOGROSSO C, TAMMARO P, COVINO G, PEPE R, CAPOGROSSO P, SANNOLO, Nicola, D., Spacone, Lamberti, Monica, R., DE ROSA, G., Ratti, C., Tedeschi, C., Capogrosso, P., Tammaro, G., Covino, R., Pepe, P., Capogrosso, Sannolo, Nicola, Spacone, D, DE ROSA, R, Ratti, G, Tedeschi, C, Capogrosso, C, Tammaro, P, Covino, G, Pepe, R, and Capogrosso, P
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- 2009
12. 'Utilizzo di nuove tecniche di imaging nel rischio cardiovascolare di lavoratori sottoposti a moviemntazione manuale dei carichi'
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LAMBERTI, Monica, VANACORE A, DE ROSA R, TEDESCHI C, SACCO M, CAPOGROSSO P, PEPE R, SANNOLO, Nicola, Lamberti, Monica, Vanacore, A, DE ROSA, R, Tedeschi, C, Sacco, M, Capogrosso, P, Pepe, R, and Sannolo, Nicola
- Published
- 2008
13. Blocco di branca sinistra in lavoratori sottoposti a movimentazione manuale di carichi con basso rischio di patologie cardiache: applicazione della tomografia computerizzata multistrato
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LAMBERTI, Monica, TEDESCHI C, SACCO M, DE ROSA R, POLIZZI I, MONTEMARANO E, MONTEMARANO M, BORRELLI F, POTO A, SASSO, Ferdinando Carlo, ALTAMURA G, PEPE R, ROTONDO, Antonio, SANNOLO, Nicola, Lamberti, Monica, Tedeschi, C, Sacco, M, DE ROSA, R, Polizzi, I, Montemarano, E, Montemarano, M, Borrelli, F, Porto, A, Sasso, Ferdinando Carlo, Altamura, G, Sannolo, Nicola, Pepe, R, Rotondo, Antonio, and Poto, A
- Published
- 2008
14. Origine anomala dell'arteria coronaria di destra dal tronco polmonare in un lavoratore soggetto a movimentazione manuale di carichi. Valutazione con MSCT coronarica
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LAMBERTI, Monica, TEDESCHI C, SACCO M, MONTEMARANO E, MONTEMARANO M, BORRELLI F, PORTO A, SASSO, Ferdinando Carlo, POLIZZI I, ALTAMURA G, TESTAGUZZA N, PEPE R, ROTONDO, Antonio, Lamberti, Monica, Tedeschi, C, Sacco, M, Montemarano, E, Montemarano, M, Borrelli, F, Porto, A, Sasso, Ferdinando Carlo, Polizzi, I, Altamura, G, Testaguzza, N, Pepe, R, and Rotondo, Antonio
- Published
- 2008
15. The molecular characterization by SSRs reveals a new South Italian kinship and the origin of the cultivar Uva di Troia
- Author
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Bergamini, C., primary, Perniola, R., additional, Cardone, M. F., additional, Gasparro, M., additional, Pepe, R., additional, Caputo, A. R., additional, and Antonacci, D., additional
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- 2016
- Full Text
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16. A new computational technique for re-entry flow calculations based upon a shock-fitting technique for unstructured grids
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Onofri, Marcello, Paciorri, Renato, Pepe, R., Bonfiglioli, A., D'Angola, A., and Colonna, G.
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- 2013
17. Schede valutative di alcuni genotipi di carciofo realizzate nell’ambito del progetto MiPAAF 'CAR-VARVI – Valorizzazione di germoplasma di carciofo attraverso la costituzione varietale e il risanamento da virus' (DM 6323/7303/09 del 11/03/2009)
- Author
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Saccardo, F., Tavazza, R., Barba, M., Morone Fortunato, I., Ferrari, V., Pepe, R., Mauromicale, G. Graifenberg A., Lanteri, Sergio, Portis, Ezio, Sonnante, G., Calabrese, N. Cadinu M., and Maiani, G.
- Published
- 2013
18. Identification of candidate children for maturity-onset diabetes of the young type 2 (MODY2) gene testing: a seven-item clinical flowchart (7-iF)
- Author
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Pinelli, M, Acquaviva, F, Barbetti, F, Caredda, E, Cocozza, S, Delvecchio, M, Mozzillo, E, Pirozzi, D, Prisco, F, Rabbone, I, Sacchetti, L, Tinto, N, Toni, S, Zucchini, S, Iafusco, D, Italian Study Group on Diabetes of the Italian Society of Pediatric Endocrinology, Diabetology, Biagioni, M, Carloni, I, Cester, Am, Cherubini, V, Giorgetti, C, Iannilli, A, Bruzzese, M, Mammì, F, Guasti, M, Lenzi, L, Pepe, R, Piccini, B, Benelli, M, Cadario, F, Calcaterra, V, Cerutti, F, Sicignano, S, Mammì, C, Lazzaro, N, Comberiati, P, Scaramuzza, A, Zuccotti, G, Redaelli, F, Gallo, F, Cappa, M, Patera, P, Schiaffini, R, Cardella, F, Salvo, C, De Marco, R, Chessa, M, Frongia, P, Ricciardi, Mr, Ripoli, C, Zedda, Ma, Citriniti, F, Chiarelli, F, Tumini, S, Coccioli, Ms, De Berardinis, F, Santoro, E, DE LUCA, Filippo, Lombardo, Fortunato, Salzano, Giuseppina, Felappi, B, Prandi, E, Frezza, E, Piccinno, E, Torelli, C, Zecchino, C, Galderisi, A, Monciotti, C, Ingletto, D, Kaufmann, P, Pasquino, B, Lera, R, Lucchesi, S, Perrotta, A, Salardi, S, Scipioni, M, Luceri, S, Stamati, F, Pianese, L, Piceno, A, Tomaselli, L, Vergerio, A, Casaburo, F, Cocca, A, Confetto, S, Forgione, E, Pelliccia, C, Picariello, S, Pisani, F, Piscopo, A, Villano, P, Zanfardino, A, Buono, P, Franzese, A, Nugnes, R, Valerio, G, Maffeis, C, Marigliano, M, Chiari, G, Iovene, B, Vanelli, M., Pinelli, Michele, Acquaviva, Fabio, Barbetti, F, Caredda, E, Cocozza, Sergio, Delvecchio, M, Mozzillo, Enza, Pirozzi, Daniele, Prisco, F, Rabbone, I, Sacchetti, Lucia, Tinto, Nadia, Toni, S, Zucchini, S, and Iafusco, D.
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Genetics and Molecular Biology (all) ,Pediatrics ,medicine.medical_specialty ,Science ,Cost-Benefit Analysis ,Decision tree ,Medicine (all) ,Biochemistry, Genetics and Molecular Biology (all) ,Agricultural and Biological Sciences (all) ,Biochemistry ,Maturity onset diabetes of the young ,Settore MED/13 - Endocrinologia ,Quality of life ,Surveys and Questionnaires ,Glucokinase ,medicine ,Humans ,Genetic Testing ,Prospective Studies ,Age of Onset ,Prospective cohort study ,Child ,Wasting ,Children ,Genetic testing ,Retrospective Studies ,Glycated Hemoglobin ,Multidisciplinary ,MODY2 ,medicine.diagnostic_test ,business.industry ,Decision Trees ,Retrospective cohort study ,medicine.disease ,Test (assessment) ,Diabetes Mellitus, Type 2 ,Italy ,Child, Preschool ,Mutation ,Quality of Life ,Medicine ,Female ,medicine.symptom ,business ,gene testing ,Research Article - Abstract
MODY2 is the most prevalent monogenic form of diabetes in Italy with an estimated prevalence of about 0.5-1.5%. MODY2 is potentially indistinguishable from other forms of diabetes, however, its identification impacts on patients' quality of life and healthcare resources. Unfortunately, DNA direct sequencing as diagnostic test is not readily accessible and expensive. In addition current guidelines, aiming to establish when the test should be performed, proved a poor detection rate. Aim of this study is to propose a reliable and easy-to-use tool to identify candidate patients for MODY2 genetic testing. We designed and validated a diagnostic flowchart in the attempt to improve the detection rate and to increase the number of properly requested tests. The flowchart, called 7-iF, consists of 7 binary "yes or no" questions and its unequivocal output is an indication for whether testing or not. We tested the 7-iF to estimate its clinical utility in comparison to the clinical suspicion alone. The 7-iF, in a prospective 2-year study (921 diabetic children) showed a precision of about the 76%. Using retrospective data, the 7-iF showed a precision in identifying MODY2 patients of about 80% compared to the 40% of the clinical suspicion. On the other hand, despite a relatively high number of missing MODY2 patients, the 7-iF would not suggest the test for 90% of the non-MODY2 patients, demonstrating that a wide application of this method might 1) help less experienced clinicians in suspecting MODY2 patients and 2) reducing the number of unnecessary tests. With the 7-iF, a clinician can feel confident of identifying a potential case of MODY2 and suggest the molecular test without fear of wasting time and money. A Qaly-type analysis estimated an increase in the patients' quality of life and savings for the health care system of about 9 million euros per year.
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- 2012
19. The rapid atmospheric monitoring system of the Pierre Auger Observatory
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Abreu, P., Aglietta, M, Ahlers, M., Ahn, M., Albuquerque, E. J., Allard, I. F. M., Allekotte, D., Allen, I., Allison, J., Almela, P., Castillo, A., Alvarez Muniz, J. A., Batista, J., Ambrosio, R. A., Aminaei, M., Anchordoqui, A., Andringa, L., Antici'C, S., Aramo, T., Arganda, C., Arqueros, E., Asorey, F., Assis, H., Aublin, P., Ave, J., Avenier, M., Avila, M., Badescu, G., Balzer, A. M., Barber, M., Barbosa, K. B., Bardenet, A. F., Barroso, R., Baughman, S. L. C., Bauml, B., Baus, J., Beatty, C., Becker, J. J., Belletoile, K. H., Bellido, A., Benzvi, J. A., Berat, S., Bertou, C., Biermann, X., Billoir, P. L., Blanco, P., Blanco, F., Bleve, M., Blumer, C., Bohacova, H., Boncioli, M., Bonifazi, D., Bonino, C., Borodai, R., Brack, N., Brancus, J., Brogueira, I., Brown, P., Bruijn, W. C., Buchholz, R., Bueno, P., Buroker, A., Burton, L., Caballero Mora, R. E., Caccianiga, K. S., Caramete, B., Caruso, L., Castellina, R., Catalano, A., Cataldi, O., Cazon, G., Cester, L., Chauvin, R., Cheng, J., Chiavassa, S. H., Chinellato, A., Diaz, J. A., Chudoba, J. C., Cilmo, J., Clay, M., Cocciolo, R. W., Collica, G., Coluccia, L., Conceicao, M. R., Contreras, R., Cook, F., Cooper, H., Coppens, M. J., Cordier, J., Coutu, A., Covault, S., Creusot, C. E., Criss, A., Cronin, A., Curutiu, J., Dagoret Campagne, A., Dallier, S., Daniel, R., Dasso, B., Daumiller, S., Dawson, K., de Almeida, B. R., De Domenico, R. M., De Donato, M., de Jong, C., De la Vega, S. J., de Mello, G., Neto, W. J. M., Mitri, Jrtd, de Souza, I., de Vries, V., del Peral, K. D., del Rio, L., Deligny, M., Dembinski, O., Dhital, H., Di Giulio, N., Castro, C., Diep, M. L. D., Diogo, P. N., Dobrigkeit, F., Docters, C., D'Olivo, W., Dong, J. C., Dorofeev, P. N., dos Anjos, A., Dova, J. C., D'Urso, M. T., Dutan, D., Ebr, I., Engel, J., Erdmann, R., Escobar, M., Espadanal, C. O., Etchegoyen, J., Luis, A., Falcke, P. F. S., Fang, H., Farrar, K., Fauth, G., Fazzini, A. C., Ferguson, N., Fick, A. P., Figueira, B., Filevich, J. M., Filipcic, A., Fliescher, A., Fracchiolla, S., Fraenkel, C. E., Fratu, E. D., Frohlich, O., Fuchs, U., Gaior, B., Gamarra, R., Gambetta, R. F., Garcia, S., Roca, B., Garcia Gamez, S. T. G., Garcia Pinto, D., Garilli, D., Bravo, G., Gemmeke, A. G., Ghia, H., Giller, P. L., Gitto, M., Glass, J., Gold, H., Golup, M. S., Albarracin, G., Berisso, F. G., Vitale, M. G., Goncalves, P. F. G., Gonzalez, P., Gookin, G., Gorgi, B., Gouffon, A., Grashorn, P., Grebe, E., Griffith, S., Grillo, N., Guardincerri, A. F., Guarino, Y., Guedes, F., Hansen, G. P., Harari, P., Harrison, D., Harton, T. A., Haungs, J. L., Hebbeker, A., Heck, T., Herve, D., Hojvat, A. E., Hollon, C., Holmes, N., Homola, V. C., Horandel, P., Horvath, J. R., Hrabovsky, P., Huber, M., Huege, D., Insolia, T., Ionita, A., Italiano, F., Jansen, A., Jarne, S., Jiraskova, C., Josebachuili, S., Kadija, M., Kampert, K., Karhan, K. H., Kasper, P., Katkov, P., Kegl, I., Keilhauer, B., Keivani, B., Kelley, A., Kemp, J. L., Kieckhafer, E., Klages, R. M., Kleifges, H. O., Kleinfeller, M., Knapp, J., Koang, J., Kotera, D. H., Krohm, K., Kromer, N., Kruppke Hansen, O., Kuempel, D., Kulbartz, D., Kunka, J. K., La Rosa, N., Lachaud, G., Lahurd, C., Latronico, D., Lauer, L., Lautridou, R., Le Coz, P., Leao, S., Lebrun, Msab and, Lebrun, D., de Oliveira, P., Letessier Selvon, M. A. L., Lhenry Yvon, A., Link, I., Lopez, K., Aguera, R., Louedec, A. L., Bahilo, K., J. L., Lu, Lucero, L., Ludwig, A., Lyberis, M., Maccarone, H., Macolino, M. C., Maldera, C., Maller, S., Mandat, J., Mantsch, D., Mariazzi, P., Marin, A. G., Marin, J., Maris, V., Falcon, I. C., Marsella, H. R. M., Martello, G., Martin, D., Martinez, L., Bravo, H., Martraire, O. M., Meza, D., Mathes, J. J. M., Matthews, H. J., Matthews, J., Matthiae, A. J., Maurel, G., Maurizio, D., Mazur, D., Medina Tanco, P. O., Melissas, G., Melo, M., Menichetti, D., Menshikov, E., Mertsch, A., Meurer, P., Meyhandan, C., Mi'Canovi'C, R., Micheletti, S., Minaya, M. I., Miramonti, I. A., Molina Bueno, L., Mollerach, L., Monasor, S., Ragaigne, M., Montanet, D. M., Morales, F., Morello, B., Moreno, C., Moreno, E., Mostafa, J. C., Moura, M., Muller, C. A., Muller, M. A., Munchmeyer, G., Mussa, M., Navarra, R., Navarro, G., Navas, J. L., Necesal, S., Nellen, P., Nelles, L., Neuser, A., Nhung, J., Niechciol, P. T., Niemietz, M., Nierstenhoefer, L., Nitz, N., Nosek, D., Nozka, D., Oehlschlager, L., Olinto, J., Ortiz, A., Pacheco, M., Selmi Dei, N., Palatka, D. P., Pallotta, M., Palmieri, J., Parente, N., Parizot, G., Parra, E., Pastor, A., Paul, S., Pech, T., Pekala, M., Pelayo, J., Pepe, R., Perrone, I. M., Pesce, L., Petermann, R., Petrera, E., Petrolini, Alessandro, Petrov, A., Pfendner, Y., Piegaia, C., Pierog, R., Pieroni, T., Pimenta, P., Pirronello, M., Platino, V., Plum, M., Ponce, M., Pontz, V. H., Porcelli, M., Privitera, A., Prouza, P., Quel, M., Querchfeld, E. J., Rautenberg, S., Ravel, J., Ravignani, O., Revenu, D., Ridky, B., Riggi, J., Risse, S., Ristori, M., Rivera, P., Rizi, H., Roberts, V., de Carvalho, J., Rodriguez, W. R., Cabo, G., Martino, I. R., Rojo, J. R., Rodriguez Frias, J. R., Ros, M. D., Rosado, G., Rossler, J., Roth, T., Rouille d'Orfeuil, M., Roulet, B., Rovero, E., Ruhle, A. C., Saftoiu, C., Salamida, A., Salazar, F., Greus, H., Salina, F. S., Sanchez, G., Santo, F., Santos, C. E., Santos, E., Sarazin, E. M., Sarkar, F., Sarkar, B., Sato, S., Scharf, R., Scherini, N., Schieler, V., Schiffer, H., Schmidt, P., Scholten, A., Schoorlemmer, O., Schovancova, H., Schovanek, J., Schroder, P., Schulte, F., Schuster, S., Sciutto, D., Scuderi, S. J., Segreto, M., Settimo, A., Shadkam, M., Shellard, A., Sidelnik, R. C., Sigl, I., Lopez, G., Sima, H. H. S., Smialkowski, O., Smida, A., Snow, R., Sommers, G. R., Sorokin, P., Spinka, J., Squartini, H., Srivastava, R., Stanic, Y. N., Stapleton, S., Stasielak, J., Stephan, J., Stutz, M., Suarez, A., Suomijarvi, F., Supanitsky, T., Susa, A. D., Sutherland, T., Swain, M. S., Szadkowski, J., Szuba, Z., Tapia, M., Tartare, A., Tascau, M., Tcaciuc, O., Thao, R., Thomas, N. T., Tiffenberg, D., Timmermans, J., Tkaczyk, C., Peixoto, W., Toma, C. J. T., Tomankova, G., Tome, L., Tonachini, B., Travnicek, A., Tridapalli, P., Tristram, D. B., Trovato, G., Tueros, E., Ulrich, M., Unger, R., Urban, M., Galicia, M., Valino, J. F. V., Valore, I., Van Aar, L., van den Berg, G., van Vliet, A. M., Varela, A., Cardenas, E., Vazquez, B. V., Vazquez, J. R., Veberic, R. A., Verzi, D., Vicha, V., Videla, J., Villasenor, M., Wahlberg, L., Wahrlich, H., Wainberg, P., Walz, O., Watson, D., Weber, A. A., Weidenhaupt, M., Weindl, K., Werner, A., Westerhoff, F., Whelan, S., Widom, B. J., Wieczorek, A., Wiencke, G., Wilczynska, L., Wilczynski, B., Will, H., Williams, M., Winchen, C., Wommer, T., Wundheiler, M., Yamamoto, B., Yapici, T., Younk, T., Yuan, P., Yushkov, G., Garcia, A., Zas, B. Z., Zavrtanik, E., Zavrtanik, D., Zaw, M., Zepeda, I., Zhou, A., Zhu, J., Silva, Y., Ziolkowski, M. Z., Pierre Auger, M., APC - Astrophysique des Hautes Energies (APC - AHE), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire SUBATECH Nantes (SUBATECH), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire d'Orsay (IPNO), PIERRE AUGER, P., Abreu, M., Aglietta, M., Ahler, E. J., Ahn, I. F. M., Albuquerque, D., Allard, I., Allekotte, J., Allen, P., Allison, A., Almela, J., Alvarez Castillo, J., Alvarez Muñiz, R., Alves Batista, M., Ambrosio, A., Aminaei, L., Anchordoqui, S., Andringa, T., Antičić, C., Aramo, E., Arganda, F., Arquero, H., Asorey, P., Assi, J., Aublin, M., Ave, M., Avenier, G., Avila, A. M., Badescu, M., Balzer, K. B., Barber, A. F., Barbosa, R., Bardenet, S. L. C., Barroso, B., Baughman f, J., Bäuml, C., Bau, J. J., Beatty, K. H., Becker, A., Bellétoile, J. A., Bellido, S., Benzvi, C., Berat, X., Bertou, P. L., Biermann, P., Billoir, F., Blanco, M., Blanco, C., Bleve, H., Blümer, M., Boháčová, D., Boncioli, C., Bonifazi, R., Bonino, N., Borodai, J., Brack, I., Brancu, P., Brogueira, W. C., Brown, R., Bruijn i, P., Buchholz, A., Bueno, L., Buroker, R. E., Burton, K. S., Caballero Mora, B., Caccianiga, L., Caramete, R., Caruso, A., Castellina, O., Catalano, G., Cataldi, L., Cazon, R., Cester, J., Chauvin, S. H., Cheng, A., Chiavassa, J. A., Chinellato, J., Chirinos Diaz, J., Chudoba, M., Cilmo, R. W., Clay, Cocciolo, Giuseppe, L., Collica, Coluccia, MARIA RITA, R., Conceição, F., Contrera, H., Cook, M. J., Cooper, J., Coppen, A., Cordier, S., Coutu, C. E., Covault, A., Creusot, A., Cri, J., Cronin, A., Curutiu, S., Dagoret Campagne, R., Dallier, B., Daniel, S., Dasso, K., Daumiller, B. R., Dawson, R. M., de Almeida, M., De Domenico, C., De Donato, S. J., de Jong, G., De La Vega, W. J. M., de Mello Junior, J. R. T., de Mello Neto, DE MITRI, Ivan, V., de Souza, K. D., de Vrie, L., del Peral, M., del Río, O., Deligny, H., Dembinski, N., Dhital, C., Di Giulio, M. L., Díaz Castro, P. N., Diep, F., Diogo, C., Dobrigkeit, W., Docter, J. C., D'Olivo, P. N., Dong, A., Dorofeev, J. C., dos Anjo, M. T., Dova, D., D'Urso, I., Dutan, J., Ebr, R., Engel, M., Erdmann, C. O., Escobar, J., Espadanal, A., Etchegoyen, P., Facal San Lui, H., Falcke, K., Fang, G., Farrar, A. C., Fauth, N., Fazzini, A. P., Ferguson, B., Fick, J. M., Figueira, A., Filevich, A., Filipčič, S., Fliescher, C. E., Fracchiolla, E. D., Fraenkel!, O., Fratu, U., Fröhlich, B., Fuch, R., Gaior, R. F., Gamarra, S., Gambetta, B., García, S. T., Garcia Roca, D., Garcia Gamez, D., Garcia Pinto, G., Garilli, A., Gascon Bravo, H., Gemmeke, P. L., Ghia, M., Giller, J., Gitto, H., Gla, M. S., Gold, G., Golup, F., Gomez Albarracin, M., Gómez Berisso, P. F., Gómez Vitale, P., Gonçalve, J. G., Gonzalez, B., Gookin, A., Gorgi, P., Gouffon, E., Grashorn, S., Grebe, N., Griffith, A. F., Grillo, Y., Guardincerri, F., Guarino, G. P., Guede, P., Hansen, D., Harari, T. A., Harrison, J. L., Harton, A., Haung, T., Hebbeker, D., Heck, A. E., Herve, C., Hojvat, N., Hollon, V. C., Holme, P., Homola, J. R., Hörandel, P., Horvath, M., Hrabovský, D., Huber, T., Huege, A., Insolia, F., Ionita, A., Italiano, S., Jansen, C., Jarne, S., Jiraskova, M., Josebachuili, K., Kadija, K. H., Kampert, P., Karhan, P., Kasper, I., Katkov, B., Kégl, B., Keilhauer, A., Keivani, J. L., Kelley, E., Kemp, R. M., Kieckhafer, H. O., Klage, M., Kleifge, J., Kleinfeller, J., Knapp, D. H., Koang, K., Kotera, N., Krohm, O., Krömer, D., Kruppke Hansen, D., Kuempel, J. K., Kulbartz, N., Kunka, G., La Rosa, C., Lachaud, D., Lahurd, L., Latronico, R., Lauer, P., Lautridou, S., Le Coz, M. S. A. B., Leão, D., Lebrun, P., Lebrun, M. A., Leigui de Oliveira, A., Letessier Selvon, I., Lhenry Yvon, K., Link, R., López, A., Lopez Agüera, K., Louedec, J., Lozano Bahilo, L., Lu, A., Lucero, M., Ludwig, H., Lyberi, M. C., Maccarone, C., Macolino, S., Maldera, J., Maller, D., Mandat, P., Mantsch, A. G., Mariazzi, J., Marin, V., Marin, I. C., Mari, H. R., Marquez Falcon, Marsella, Giovanni, Martello, Daniele, L., Martin, H., Martinez, O., Martínez Bravo, D., Martraire, J. J., Masías Meza, H. J., Mathe, J., Matthew, J. A. J., Matthew, G., Matthiae, D., Maurel, D., Maurizio, P. O., Mazur, G., Medina Tanco, M., Melissa, D., Melo, E., Menichetti, A., Menshikov, P., Mertsch, C., Meurer, R., Meyhandan, S., Mićanović, M. I., Micheletti, I. A., Minaya, L., Miramonti, L., Molina Bueno, S., Mollerach, M., Monasor, D., Monnier Ragaigne, F., Montanet, B., Morale, C., Morello, E., Moreno, J. C., Moreno, M., Mostafá, C. A., Moura, M. A., Muller, G., Müller, M., Münchmeyer, R., Mussa, G., Navarra ‡, J. L., Navarro, S., Nava, P., Necesal, L., Nellen, A., Nelle, J., Neuser, P. T., Nhung, M., Niechciol, L., Niemietz, N., Nierstenhoefer, D., Nitz, D., Nosek, L., Nožka, J., Oehlschläger, A., Olinto, M., Ortiz, N., Pacheco, D., Pakk Selmi Dei, M., Palatka, J., Pallotta, N., Palmieri, G., Parente, E., Parizot, A., Parra, S., Pastor, T., Paul, M., Pech, J., Pękala, R., Pelayo, I. M., Pepe, Perrone, Lorenzo, R., Pesce, E., Petermann, S., Petrera, A., Petrolini, Y., Petrov, C., Pfendner, R., Piegaia, T., Pierog, P., Pieroni, M., Pimenta, V., Pirronello, M., Platino, M., Plum, V. H., Ponce, M., Pontz, A., Porcelli, P., Privitera, M., Prouza, E. J., Quel, S., Querchfeld, J., Rautenberg, O., Ravel, D., Ravignani, B., Revenu, J., Ridky, S., Riggi, M., Risse, P., Ristori, H., Rivera, V., Rizi, J., Robert, W., Rodrigues de Carvalho, G., Rodriguez, I., Rodriguez Cabo, J., Rodriguez Martino, J., Rodriguez Rojo, M. D., Rodríguez Fría, G., Ro, J., Rosado, T., Rossler, M., Roth, B., Rouillé d'Orfeuil, E., Roulet, A. C., Rovero, C., Rühle, A., Saftoiu, F., Salamida, H., Salazar, F., Salesa Greu, G., Salina, F., SÃ! ¡nchez, C. E., Santo, E., Santo, E. M., Santo, F., Sarazin, B., Sarkar, S., Sarkar, R., Sato, N., Scharf, V., Scherini, H., Schieler, P., Schiffer, A., Schmidt, O., Scholten, H., Schoorlemmer, J., Schovancova, P., Schovánek, F., Schröder, S., Schulte, D., Schuster, S. J., Sciutto, M., Scuderi, A., Segreto, M., Settimo, A., Shadkam, R. C., Shellard, I., Sidelnik, G., Sigl, H. H., Silva Lopez, O., Sima, A., Śmiałkowski, R., Šmída, G. R., Snow, P., Sommer, J., Sorokin, H., Spinka, R., Squartini, Y. N., Srivastava, S., Stanic, J., Stapleton, J., Stasielak, M., Stephan, A., Stutz, F., Suarez, T., Suomijärvi, A. D., Supanitsky, T., Šuša, M. S., Sutherland, J., Swain, Z., Szadkowski, M., Szuba, A., Tapia, M., Tartare, O., Taşcău, R., Tcaciuc, N. T., Thao, D., Thoma, J., Tiffenberg, C., Timmerman, W., Tkaczyk, C. J., Todero Peixoto, G., Toma, L., Tomankova, B., Tomé, A., Tonachini, P., Travnicek, D. B., Tridapalli, G., Tristram, E., Trovato, M., Tuero, R., Ulrich, M., Unger, M., Urban, J. F., Valdés Galicia, I., Valiño, L., Valore, G., van Aar, A. M., van den Berg, A., van Vliet, E., Varela, B., Vargas Cárdena, J. R., Vázquez, R. A., Vázquez, D., Veberič, V., Verzi, J., Vicha, M., Videla, L., Villaseñor, H., Wahlberg, P., Wahrlich, O., Wainberg, D., Walz, A. A., Watson, M., Weber, K., Weidenhaupt, A., Weindl, F., Werner, S., Westerhoff, B. J., Whelan, A., Widom, G., Wieczorek, L., Wiencke, B., Wilczyńska, H., Wilczyński, M., Will, C., William, T., Winchen, M., Wommer, B., Wundheiler, T., Yamamoto a, T., Yapici, P., Younk, G., Yuan, A., Yushkov, B., Zamorano Garcia, E., Za, D., Zavrtanik, M., Zavrtanik, I., Zaw h, A., Zepeda b, J., Zhou, Y., Zhu, M., Zimbres Silva, M. Ziolkowski, ., P. Abreu, M. Aglietta, M. Ahler, E.J. Ahn, I.F.M. Albuquerque, D. Allard, I. Allekotte, J. Allen, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, R. Alves Batista, M. Ambrosio, A. Aminaei, L. Anchordoqui, S. Andringa, T. Antičić, C. Aramo, E. Arganda, F. Arquero, H. Asorey, P. Assi, J. Aublin, M. Ave, M. Avenier, G. Avila, A.M. Badescu, M. Balzer, K.B. Barber, A.F. Barbosa, R. Bardenet, S.L.C. Barroso, B. Baughman f, J. Bäuml, C. Bau, J.J. Beatty, K.H. Becker, A. Bellétoile, J.A. Bellido, S. BenZvi, C. Berat, X. Bertou, P.L. Biermann, P. Billoir, F. Blanco, M. Blanco, C. Bleve, H. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, R. Bonino, N. Borodai, J. Brack, I. Brancu, P. Brogueira, W.C. Brown, R. Bruijn i, P. Buchholz, A. Bueno, L. Buroker, R.E. Burton, K.S. Caballero-Mora, B. Caccianiga, L. Caramete, R. Caruso, A. Castellina, O. Catalano, G. Cataldi, L. Cazon, R. Cester, J. Chauvin, S.H. Cheng, A. Chiavassa, J.A. Chinellato, J. Chirinos Diaz, J. Chudoba, M. Cilmo, R.W. Clay, G. Cocciolo, L. Collica, M.R. Coluccia, R. Conceição, F. Contrera, H. Cook, M.J. Cooper, J. Coppen, A. Cordier, S. Coutu, C.E. Covault, A. Creusot, A. Cri, J. Cronin, A. Curutiu, S. Dagoret-Campagne, R. Dallier, B. Daniel, S. Dasso, K. Daumiller, B.R. Dawson, R.M. de Almeida, M. De Domenico, C. De Donato, S.J. de Jong, G. De La Vega, W.J.M. de Mello Junior, J.R.T. de Mello Neto, I. De Mitri, V. de Souza, K.D. de Vrie, L. del Peral, M. del Río, O. Deligny, H. Dembinski, N. Dhital, C. Di Giulio, M.L. Díaz Castro, P.N. Diep, F. Diogo, C. Dobrigkeit, W. Docter, J.C. D'Olivo, P.N. Dong, A. Dorofeev, J.C. dos Anjo, M.T. Dova, D. D'Urso, I. Dutan, J. Ebr, R. Engel, M. Erdmann, C.O. Escobar, J. Espadanal, A. Etchegoyen, P. Facal San Lui, H. Falcke, K. Fang, G. Farrar, A.C. Fauth, N. Fazzini, A.P. Ferguson, B. Fick, J.M. Figueira, A. Filevich, A. Filipčič, S. Fliescher, C.E. Fracchiolla, E.D. Fraenkel!, O. Fratu, U. Fröhlich, B. Fuch, R. Gaior, R.F. Gamarra, S. Gambetta, B. García, S.T. Garcia Roca, D. Garcia-Gamez, D. Garcia-Pinto, G. Garilli, A. Gascon Bravo, H. Gemmeke, P.L. Ghia, M. Giller, J. Gitto, H. Gla, M.S. Gold, G. Golup, F. Gomez Albarracin, M. Gómez Berisso, P.F. Gómez Vitale, P. Gonçalve, J.G. Gonzalez, B. Gookin, A. Gorgi, P. Gouffon, E. Grashorn, S. Grebe, N. Griffith, A.F. Grillo, Y. Guardincerri, F. Guarino, G.P. Guede, P. Hansen, D. Harari, T.A. Harrison, J.L. Harton, A. Haung, T. Hebbeker, D. Heck, A.E. Herve, C. Hojvat, N. Hollon, V.C. Holme, P. Homola, J.R. Hörandel, P. Horvath, M. Hrabovský, D. Huber, T. Huege, A. Insolia, F. Ionita, A. Italiano, S. Jansen, C. Jarne, S. Jiraskova, M. Josebachuili, K. Kadija, K.H. Kampert, P. Karhan, P. Kasper, I. Katkov, B. Kégl, B. Keilhauer, A. Keivani, J.L. Kelley, E. Kemp, R.M. Kieckhafer, H.O. Klage, M. Kleifge, J. Kleinfeller, J. Knapp, D.-H. Koang, K. Kotera, N. Krohm, O. Krömer, D. Kruppke-Hansen, D. Kuempel, J.K. Kulbartz, N. Kunka, G. La Rosa, C. Lachaud, D. LaHurd, L. Latronico, R. Lauer, P. Lautridou, S. Le Coz, M.S.A.B. Leão, D. Lebrun, P. Lebrun, M.A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, R. López, A. Lopez Agüera, K. Louedec, J. Lozano Bahilo, L. Lu, A. Lucero, M. Ludwig, H. Lyberi, M.C. Maccarone, C. Macolino, S. Maldera, J. Maller, D. Mandat, P. Mantsch, A.G. Mariazzi, J. Marin, V. Marin, I.C. Mari, H.R. Marquez Falcon, G. Marsella, D. Martello, L. Martin, H. Martinez, O. Martínez Bravo, D. Martraire, J.J. Masías Meza, H.J. Mathe, J. Matthew, J.A.J. Matthew, G. Matthiae, D. Maurel, D. Maurizio, P.O. Mazur, G. Medina-Tanco, M. Melissa, D. Melo, E. Menichetti, A. Menshikov, P. Mertsch, C. Meurer, R. Meyhandan, S. Mićanović, M.I. Micheletti, I.A. Minaya, L. Miramonti, L. Molina-Bueno, S. Mollerach, M. Monasor, D. Monnier Ragaigne, F. Montanet, B. Morale, C. Morello, E. Moreno, J.C. Moreno, M. Mostafá, C.A. Moura, M.A. Muller, G. Müller, M. Münchmeyer, R. Mussa, G. Navarra ‡, J.L. Navarro, S. Nava, P. Necesal, L. Nellen, A. Nelle, J. Neuser, P.T. Nhung, M. Niechciol, L. Niemietz, N. Nierstenhoefer, D. Nitz, D. Nosek, L. Nožka, J. Oehlschläger, A. Olinto, M. Ortiz, N. Pacheco, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, N. Palmieri, G. Parente, E. Parizot, A. Parra, S. Pastor, T. Paul, M. Pech, J. Pękala, R. Pelayo, I.M. Pepe, L. Perrone, R. Pesce, E. Petermann, S. Petrera, A. Petrolini, Y. Petrov, C. Pfendner, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, V.H. Ponce, M. Pontz, A. Porcelli, P. Privitera, M. Prouza, E.J. Quel, S. Querchfeld, J. Rautenberg, O. Ravel, D. Ravignani, B. Revenu, J. Ridky, S. Riggi, M. Risse, P. Ristori, H. Rivera, V. Rizi, J. Robert, W. Rodrigues de Carvalho, G. Rodriguez, I. Rodriguez Cabo, J. Rodriguez Martino, J. Rodriguez Rojo, M.D. Rodríguez-Fría, G. Ro, J. Rosado, T. Rossler, M. Roth, B. Rouillé-d'Orfeuil, E. Roulet, A.C. Rovero, C. Rühle, A. Saftoiu, F. Salamida, H. Salazar, F. Salesa Greu, G. Salina, F. SÃ! ¡nchez, C.E. Santo, E. Santo, E.M. Santo, F. Sarazin, B. Sarkar, S. Sarkar, R. Sato, N. Scharf, V. Scherini, H. Schieler, P. Schiffer, A. Schmidt, O. Scholten, H. Schoorlemmer, J. Schovancova, P. Schovánek, F. Schröder, S. Schulte, D. Schuster, S.J. Sciutto, M. Scuderi, A. Segreto, M. Settimo, A. Shadkam, R.C. Shellard, I. Sidelnik, G. Sigl, H.H. Silva Lopez, O. Sima, A. Śmiałkowski, R. Šmída, G.R. Snow, P. Sommer, J. Sorokin, H. Spinka, R. Squartini, Y.N. Srivastava, S. Stanic, J. Stapleton, J. Stasielak, M. Stephan, A. Stutz, F. Suarez, T. Suomijärvi, A.D. Supanitsky, T. Šuša, M.S. Sutherland, J. Swain, Z. Szadkowski, M. Szuba, A. Tapia, M. Tartare, O. Taşcău, R. Tcaciuc, N.T. Thao, D. Thoma, J. Tiffenberg, C. Timmerman, W. Tkaczyk, C.J. Todero Peixoto, G. Toma, L. Tomankova, B. Tomé, A. Tonachini, P. Travnicek, D.B. Tridapalli, G. Tristram, E. Trovato, M. Tuero, R. Ulrich, M. Unger, M. Urban, J.F. Valdés Galicia, I. Valiño, L. Valore, G. van Aar, A.M. van den Berg, A. van Vliet, E. Varela, B. Vargas Cárdena, J.R. Vázquez, R.A. Vázquez, D. Veberič, V. Verzi, J. Vicha, M. Videla, L. Villaseñor, H. Wahlberg, P. Wahrlich, O. Wainberg, D. Walz, A.A. Watson, M. Weber, K. Weidenhaupt, A. Weindl, F. Werner, S. Westerhoff, B.J. Whelan, A. Widom, G. Wieczorek, L. Wiencke, B. Wilczyńska, H. Wilczyński, M. Will, C. William, T. Winchen, M. Wommer, B. Wundheiler, T. Yamamoto a, T. Yapici, P. Younk, G. Yuan, A. Yushkov, B. Zamorano Garcia, E. Za, D. Zavrtanik, M. Zavrtanik, I. Zaw h, A. Zepeda b, J. Zhou, Y. Zhu, M. Zimbres Silva, M. Ziolkowski ., Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Dipartimento di Astronomia, Universita degli Studi di Bologna, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO)-Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Aramo, Carla, D'Urso, Domenico, Guarino, Fausto, Valore, Laura, The Pierre Auger, Collaboration, KVI - Center for Advanced Radiation Technology, Research unit Astroparticle Physics, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Dipartimento di Astronomia, Universita degli Studi di Bologna, Università di Bologna [Bologna] (UNIBO)-Università di Bologna [Bologna] (UNIBO), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), and PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)
- Subjects
[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE] ,Astronomy ,FOS: Physical sciences ,Cosmic ray ,Real-time monitoring ,01 natural sciences ,Large detector systems for particle and astroparticle physics, Real-time monitoring, Control and monitor systems online ,Optical telescope ,Observatory ,0103 physical sciences ,SHOWERS ,Large detector systems for particle and astroparticle physics ,Control and monitor systems online ,FLUORESCENCE ,010303 astronomy & astrophysics ,Instrumentation ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,DETECTOR ,Mathematical Physics ,Remote sensing ,Event reconstruction ,Pierre Auger Observatory ,High Energy Astrophysical Phenomena (astro-ph.HE) ,010308 nuclear & particles physics ,[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE] ,Física ,ENERGY-SPECTRUM ,Monitoring program ,Aerosol ,ATMOSFERA (MONITORAMENTO) ,Air shower ,Experimental High Energy Physics ,Física nuclear ,Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The Pierre Auger Observatory is a facility built to detect air showers produced by cosmic rays above 1017 eV. During clear nights with a low illuminated moon fraction, the UV fluorescence light produced by air showers is recorded by optical telescopes at the Observatory. To correct the observations for variations in atmospheric conditions, atmospheric monitoring is performed at regular intervals ranging from several minutes (for cloud identification) to several hours (for aerosol conditions) to several days (for vertical profiles of temperature, pressure, and humidity). In 2009, the monitoring program was upgraded to allow for additional targeted measurements of atmospheric conditions shortly after the detection of air showers of special interest, e. g., showers produced by very high-energy cosmic rays or showers with atypical longitudinal profiles. The former events are of particular importance for the determination of the energy scale of the Observatory, and the latter are characteristic of unusual air shower physics or exotic primary particle types. The purpose of targeted (or "rapid") monitoring is to improve the resolution of the atmospheric measurements for such events. In this paper, we report on the implementation of the rapid monitoring program and its current status. The rapid monitoring data have been analyzed and applied to the reconstruction of air showers of high interest, and indicate that the air fluorescence measurements affected by clouds and aerosols are effectively corrected using measurements from the regular atmospheric monitoring program. We find that the rapid monitoring program has potential for supporting dedicated physics analyses beyond the standard event reconstruction.
- Published
- 2012
20. La conservazione ex situ della biodiversità delle specie vegetali spontanee e coltivate in Italia. Stato dell'arte, criticità e azioni da compiere
- Author
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Acosta, A., Alonzi, A., Annicchiarico, P., Antonacci, D., Aprile, S., Avanzato, D., Bacchetta, G., Bacchetta, L., Bagella, S., Baiocco, M., Baldi, M., Barbera, G., Bartolini, G., Baruzzi, G., Bedini, G., Belletti, P., Benvenuti, S., Bergamaschi, M., Bergamo, P., Bertin, L., Bianchi, P. G., Biscotti, N., Blando, F., Bonito, A., Bonomi, C., Borgo, M., Branca, F., Brandoni, L., Bretzel, F., Brundu, G., Bullitta, S., Burchi, G., Bussotti, F., Caboni, E., Calvo, E., Camarda, I., Camoriano, L., Cantini, C., Capriolo, A., Capuana, M., Carrabba, P., Casti, M., Cattabriga, A., Ceriani, R., Cervelli, C., Civale, P., Clerici, F., Colletti, L., Contri, M. L., Converio, F., Crescente, M. F., Crinó, P., Crosti, R., Damiano, C., Danti, R., DE GIORGIO, D., DE LISI, A., D'Egidio, M. G., DE MATTEIS TORTORA, M., DE STEFANIS, E., Delfine, S., DE ROGATIS, A., DI CANDILO, M., DI GIUSEPPE, E., D’Ovidio, C., Dominione, V., Ducci, F., Engel, P., Ercole, S., Esposito, S., Falcinelli, M., Farina, E., Fenu, G., Ferrari, V., Ferroni, F., Ficcadenti, N., Fideghelli, C., Filigheddu, R., Fineschi, S., Fiorentin, R., Franca, A., Forte, L., Fusaro, E., Gardiman, M., Gentile, A., Gentili, R., Germanà, M. A., Giacanelli, V., Giannini, M., Giannini, R., Giardina, F., Giovannini, A., Giovannini, D., Gironi, R., Giust, M., Gorian, F., Gras, M., Grassotti, A., Gratani, L., Grossoni, P., Guidi, S., Ianni, G., Inglese, P., Insero, O., Izzi, F., LA MALFA, S., LA MANTIA, T., Labra, M., Laghetti, G., Lamastra, S., Lambardi, M., LI DESTRI NICOSIA, O., Lioi, L., Liverani, A., Logozzo, G., Longhi, E., Lorenzetti, F., Lorenzetti, S., Lupotto, E., Macculi, M., Magaldi, T., Malfanti, F., Malvolti, M. E., Mameli, G., Margiotta, B., Marino, D., Marino, M., Mariotti, M. G., Mascolo, R. A., Mattana, E., Meloni, F., Milan, C., Montanari, I., Montesano, V., Moraldi, M., Mucciarelli, M., Mughini, G., Mulè, P., Negri, V., Negro, D., Nepi, M., Nervo, G., Nesti, U., Nobili, P., Notarmuzi, M. C., Orru, M., Pacini, E., Padulosi, S., Pallotta, L., Palmieri, M., Palumbo, M., Paolucci, G., Paris, P. L., Pasqua, G., Pasqui, M., Pasquini, M., Pavone, P., Pelillo, R., Pepe, R., Peratoner, G., Perri, E., Perrino, P., Petrucci, B., Pettenella, D., Piccini, C., Piergiovanni, A. R., Piffanelli, P., Pignone, D., Piluzza, G., Piotto, B., Podda, L., Polignano, G., Pollutri, A., Pontecorvo, C., Porceddu, E., Porqueddu, C., Puglisi, S., Quarta, R., Rainini, F., G. A., Re, Recupero, S., Redaelli, R., REFORGIATO RECUPERO, G., Resta, P., Romano, D., Ronchi, B., Rosellini, D., Rossi, G., Sabatti, M., Sabatini, A. G., Saccardo, F., Salvati, R., Salvioni, C., Santini, A., Saporito, L., Sarli, G., SCARASCIA MUGNOZZA, G. T., SCARASCIA MUGNOZZA, G., Scarpa, G. M., Schiavella, P., Schiavi, M., Schiavon, L., Schirone, B., Scippa, G., Sgarbi, Elisabetta, Sgorbati, S., Sgrulletta, D., Simeone, A. M., Sonnante, G., Sorrentino, C., Sottile, F., Spada, P., Speranza, M., Stanca, M., Stanisci, A., Sulas, L., Terzi, M., Terzi, V., Tomaselli, V., Tomat, E., Torricelli, R., Tugliozzi, C., Urbano, M., Vaccino, P., Valletta, A., Varone, L., Vender, C., Vento, D., Veronesi, F., Veronesi, M., Vettori, C., Vietto, L., Villa, M., Villani, G., Vlahov, G., Zanatta, K., and Zizzo, G.
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biodiversità vegetale ,banche del germoplasma ,conservazione ex situ ,conservazione "on farm" - Published
- 2010
21. La conservazione ex situ della biodiversità delle specie vegetalispontanee e coltivate in Italia Stato dell’arte, criticità e azioni da compiere
- Author
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Acosta, Alonzi, A., Annicchiarico, P., Antonacci, D., Aprile, S., Avanzato, D., Bacchetta, G., Bacchetta, L., Bagella, S., Baiocco, M., Baldi, M., Barbera, G., Bartolini, G., Baruzzi, G., Bedini, G., Belletti, P., Benvenuti, S., Bergamaschi, M., Bergamo, P., Bertin, L., Bianchi, Pg, Biscotti, N., Blando, F., Bonito, A., Bonomi, C., Borgo, M., Branca, F., Brandoni, L., Bretzel, F., Brundu, G., Bullitta, S., Burchi, G., Bussotti, F., Caboni, E., Calvo, E., Camarda, I., Camoriano, L., Cantini, C., Capriolo, A., Capuana, M., Carrabba, P., Casti, M., Cattabriga, A., Ceriani, R., Cervelli, C., Civale, P., Clerici, F., Colletti, L., Contri, Ml, Converio, F., Crescente, M. F., Crinó, P., Crosti, R., Damiano, C., Danti, R., DE GIORGIO, D., DE LISI, A., D'Egidio, M. G., DE MATTEIS TORTORA, M., DE STEFANIS, E., Delfine, S., DE ROGATIS, A., DI CANDILO, M., DI GIUSEPPE, E., D’Ovidio, C., Dominione, V., Ducci, F., Engel, P., Ercole, S., Esposito, S., Falcinelli, M., Farina, E., Fenu, G., Ferrari, V., Ferroni, F., Ficcadenti, N., Fideghelli, C., Filigheddu, R., Fineschi, S., Fiorentin, R., Franca, A., Forte, L., Fusaro, E., Gardiman, M., Gentile, A., Gentili, R., Germanà, M., Giacanelli, V., Giannini, M., Giannini, R., Giardina, F., Agiovannini, Giovannini, D., Gironi, R., Giust, M., Gorian, F., Gras, M., Grassotti, A., Gratani, L., Grossoni, P., Guidi, S., Ianni, G., Inglese, P., Insero, O., Izzi, F., LA MALFA, S., LA MANTIA, T., Labra, M., Laghetti, G., Lamastra, S., Lambardi, M., Lanza, B., LI DESTRI NICOSIA, O., Lioi, L., Liverani, A., Logozzo, G., Longhi, E., Lorenzetti, F., Lorenzetti, S., Lupotto, E., Macculi, M., Magaldi, T., Malfanti, F., Malvolti, M. E., Mameli, G., Margiotta, B., Marino, D., Marino, M., Mariotti, Mauro, Mascolo, R. A., Mattana, E., Meloni, F., Milan, C., Montanari, I., Montesano, V., Moraldi, M., Mucciarelli, M., Mughini, G., Mulè, P., Negri, V., Negro, D., Nepi, M., Nervo, G., Nesti, U., Nobili, P., Notarmuzi, M. C., Orru, M., Pacini, E., Padulosi, S., Pallotta, L., Palmieri, M., Palumbo, M., Paolucci, G., Paris, P. L., Pasqua, G., Pasqui, M., Pasquini, M., Pavone, P., Pelillo, R., Pepe, R., Peratoner, G., Perri, E., Perrino, P., Petrucci, B., Pettenella, D., Piccini, C., Piergiovanni, A. R., Piffanelli, P., Pignone, D., Piluzza, G., Piotto, B., Podda, L., Polignano, G., Pollutri, A., Pontecorvo, C., Porceddu, E., Porqueddu, C., Puglisi, S., Quarta, R., Rainini, F., G. A., Re, Recupero, S., Redaelli, R., REFORGIATO RECUPERO, G., Resta, P., Romano, D., Ronchi, B., Rosellini, D., Rossi, G., Sabatti, M., Sabatini, A. G., Saccardo, F., Salvati, R., Salvioni, C., Santini, A., Saporito, L., Sarli, G., SCARASCIA MUGNOZZA, G. T., SCARASCIA MUGNOZZA, G., Scarpa, G. M., Schiavella, P., Schiavi, M., Schiavon, L., Schirone, B., Scippa, G., Sgarbi, E., Sgorbati, S., Sgrulletta, D., Simeone, A. M., Sonnante, G., Sorrentino, C., Sottile, F., Spada, P., Speranza, M., Stanca, M., Stanisci, A., Sulas, L., Terzi, M., Terzi, V., Tomaselli, V., Tomat, E., Torricelli, R., Tugliozzi, C., Urbano, M., Vaccino, P., Valletta, A., Varone, L., Vender, C., Vento, D., Veronesi, F., Veronesi, M., Vettori, C., Vietto, L., Villa, M., Villani, G., Vlahov, G., Zanatta, K., and Zizzo, G.
- Published
- 2010
22. Prolungamento della shelf-life del peperone in IV gamma
- Author
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Adiletta, Giuseppina, Orilio, Paola, Sannini, Adriana, Pepe, R., DI MATTEO, Marisa, and Albanese, Donatella
- Published
- 2010
23. Mitimycyn C plus vindesine plus etposide (MEV) versus mitomycin C plus vindesine plus cisplatin (MVP)in stage IV non-small-cell lung cancer: a phase III multicentre randomised trial
- Author
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GRIDELLI C, PERRONE F, PALMERI S, D'APRILE M, COGNETTI F, ROSSI A, GEBBIA V, PEPE R, VELTRI E, AIROMA G, RUSSO A, INCORONATO P, SCINTO AF, PALAZZOLO G, NATALI M, LEONARDI V, DE PLACIDO S, BIANCO AR, GALLO, Ciro, Gridelli, C, Perrone, F, Palmeri, S, D'Aprile, M, Cognetti, F, Rossi, A, Gebbia, V, Pepe, R, Veltri, E, Airoma, G, Russo, A, Incoronato, P, Scinto, Af, Palazzolo, G, Natali, M, Leonardi, V, Gallo, Ciro, DE PLACIDO, S, and Bianco, Ar
- Published
- 1996
24. Effects of defibrotide in patients with chronic deep insufficiency - The PROVEDIS study
- Author
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Coccheri, S, Andreozzi, Gm, D'Addato, M, Gensini, Gf, Garibaldi, O, Signorelli, S, Di Pino, L, Belardi, P, Grana, A, Belcaro, G, Incandela, G, Laurora, G, Biasi, Gm, Bellucci, M, Careggi, P, Innocenti, Aa, Frosini, P, Borromeo, Osc, Bonfardeci, G, Cimminiello, C, Arpaia, G, Bracale, Cg, Selvetella, L, De Rosa, V, Martini, L, Coppi, G, Marra, F, Stella, A, Mirelli, M, Donini, I, Viaggi, R, Cataldi, A, Ferrero, S, Dorigo, B, Cameli, A, Licata, G, Pinto, A, Mannarino, Elmo, Pasqualini, Leonella, Vaudo, Gaetano, Marchitelli, E, Pepe, R, Novo, S, Tantillo, R, Nuzzaci, G, Righi, D, Pitzus, F, Manconi, E, Ponzio, F, Rizzon, P, Ciccone, M, Campagna, Mg, Scondotto, G, Aloisi, D, Valitutti, P, and Fornino, G.
- Published
- 2004
25. ed phase II study of mitomycin c, etoposide and vindesine (MEV) in metastatic stage IV, Non small cell lug cancer
- Author
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Gridelli C., Pepe R. , Palmeri S., Iacobelli S., Gentile M., Gebbia V., Gruffi C., Airoma G., PALMIERI, GIOVANNELLA, Gridelli, C., Pepe R., Palmeri S., Iacobelli, S., Gentile, M., Gebbia, V., Gruffi, C., Airoma, G., and Palmieri, Giovannella
- Published
- 1991
26. Linee-guida per la diagnosi e il trattamento della trombosi venosa profonda
- Author
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Palareti, G, Agnelli, G, Antignani, Pl, Bonifacio, M, Giampalma, E, Golfieri, R, Legnani, C, Losinno, F, Lusiani, L, Macri, I, Martignani, A, Moia, M, Pedrini, L, Pepe, R, Pesavento, R, Pini, M, Prandoni, Paolo, Prisco, D, Rossi, C, Signorelli, S, Sonaglia, F, Ugliola, M, and Verlato, F.
- Published
- 2000
27. Femoral catheters: safety and efficacy in peripheral blood stem cell collection
- Author
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Adorno, G, Zinno, F, Lanti, A, Ballatore, G, Masi, M, Cudillo, L, DEL POETA, G, Riccitelli, A, DEL PRINCIPE, Mi, Pepe, R, Marchitelli, E, Morosetti, M, Meloni, C, Isacchi, G, and Amadori, S
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femoral catheter ,PBSC collection ,Settore MED/05 - Patologia Clinica - Published
- 1999
28. IMPROVING THE ARTICHOKE QUALITY OF CAMPANIA REGION
- Author
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Rofrano, G., primary, Trotta, N., additional, Pepe, R., additional, Pagnotta, M.A., additional, Saccardo, F., additional, and Cardi, T., additional
- Published
- 2013
- Full Text
- View/download PDF
29. Development of a 4 hour protocol for simultaneous single gene disorder (SGD) and comprehensive chromosomal aneuploidy screening (CCS) from a single trophectoderm (TE) biopsy
- Author
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Pepe, R., primary, Tao, X., additional, Su, J., additional, Stevens, J., additional, Treff, N., additional, and Scott, R., additional
- Published
- 2012
- Full Text
- View/download PDF
30. PGD for monogenic disease by direct mutation analysis alone in 2 or more cells is more reliable than multiple marker analysis in single cells
- Author
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Tao, X., primary, Su, J., additional, Pepe, R., additional, Northrop, L.E., additional, Ferry, K.M., additional, and Treff, N.R., additional
- Published
- 2011
- Full Text
- View/download PDF
31. ChemInform Abstract: Preparation of 2,3-Disubstituted-4,5-dihydrothiophenes and Thiophenes Using the Intramolecular Non-Classical Wittig Reaction of Thiolcarboxylates
- Author
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CHATTERJEE, P., primary, MURPHY, P. J., additional, PEPE, R., additional, and SHAW, M., additional
- Published
- 2010
- Full Text
- View/download PDF
32. Prevalence of coronary artery intramyocardial course in a large population of clinical patients detected by multislice computed tomography coronary angiography
- Author
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De Rosa, R., primary, Sacco, M., additional, Tedeschi, C., additional, Pepe, R., additional, Capogrosso, P., additional, Montemarano, E., additional, Rotondo, A., additional, Runza, G., additional, Midiri, M., additional, and Cademartiri, F., additional
- Published
- 2008
- Full Text
- View/download PDF
33. Neural adaptability and inspection time.
- Author
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Garaas, T., Pepe, R., Lo, H., Nestor, P., and Pomplun, M.
- Published
- 2009
- Full Text
- View/download PDF
34. Femoral Catheters: Safety and Efficacy in Peripheral Blood Stem Cell Collection
- Author
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Adorno, G., primary, Zinno, F., additional, Bruno, A., additional, Lanti, A., additional, Ballatore, G., additional, Masi, M., additional, Cudillo, L., additional, Del Poeta, G., additional, Riccitelli, A., additional, Del Principe, M.I., additional, Pepe, R., additional, Marchitelli, E., additional, Morosetti, M., additional, Meloni, C., additional, Isacchi, G., additional, and Amadori, S., additional
- Published
- 1999
- Full Text
- View/download PDF
35. Mitomycin C plus vindesine plus etoposide (MEV) versus mitomycin C plus vindesine plus cisplatin (MVP) in stage IV non-small-cell lung cancer: A phase III multicentre randomised trial
- Author
-
Gridelli, C., primary, Perron, F., additional, Palmeri, S., additional, D'Aprile, M., additional, Cognetti, F., additional, Rossi, A., additional, Gebbia, V., additional, Pepe, R., additional, Veltri, E., additional, Airoma, G., additional, Russo, A., additional, Incoronato, P., additional, Scinto, A.F., additional, Palazzolo, G., additional, Natali, M., additional, Leonardi, V., additional, Gallo, C., additional, De Placido, S., additional, and Bianco, A.R., additional
- Published
- 1996
- Full Text
- View/download PDF
36. Bacteremia in a Patient with Non-Urinary-Tract Infection Due to Corynebacterium urealyticum
- Author
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Wood, C. A., primary and Pepe, R., additional
- Published
- 1994
- Full Text
- View/download PDF
37. Ondansetron in the prophylaxis of nausea and vomiting induced by carboplatin combination chemotherapy
- Author
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Arpinelli, F., primary, Gridelli, C., additional, Incoronato, P., additional, Airoma, G., additional, Pepe, R., additional, and Bianco, A.R., additional
- Published
- 1993
- Full Text
- View/download PDF
38. Second-Line Chemotherapy of Advanced Colorectal Cancer with Sequential High-Dose Methotrexate and 5-Fluorouracil
- Author
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Palmieri, G., primary, Gridelli, C., additional, Airoma, G., additional, Pepe, R., additional, Incoronato, P., additional, Caponigro, F., additional, and Bianco, A.R., additional
- Published
- 1991
- Full Text
- View/download PDF
39. [Anomalous origin of the circumflex artery from the right aortic sinus: assessment with conventional coronary angiography and multislice computed tomography]
- Author
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Tedeschi C, Roberto De Rosa, Ratti G, Sacco M, Borrelli F, Runza G, Midiri M, Tuccillo B, Pepe R, Capogrosso P, TEDESCHI C, DE ROSA R, RATTI G, SACCO M, BORRELLI F, RUNZA G, MIDIRI M, TUCCILLO B, PEPE R, and CAPOGROSSO P
40. Simulation of fixed-point operations with high-level languages.
- Author
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Pepe, R. and Rogers, J.
- Published
- 1987
- Full Text
- View/download PDF
41. Mitomycin C plus vindesine or cisplatin plus epirubicin in previously treated patients with symptomatic advanced non-small-cell lung cancer.
- Author
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Gridelli, Cesare, Airoma, Giuseppe, Incoronato, Pasquale, Pepe, Rosario, Palazzolo, Giovanni, Rossi, Antonio, Bianco, Angelo, Gridelli, C, Airoma, G, Incoronato, P, Pepe, R, Palazzolo, G, Rossi, A, and Bianco, A R
- Abstract
A total of 40 previously treated patients with symptomatic advanced non-small-cell lung cancer (NSCLC) were subjected to second-line chemotherapy with mitomycin C plus vindesine (MV) or cisplatin plus epirubicin (PE). The 12 patients treated with the MV regimen showed no objective response (OR) or symptom palliation. In the 28 patients who received the PE regimen, we obtained a 25% partial response rate, with amelioration of tumor-related symptoms occurring in 35.7% of cases and improvement in the performance status being noted in 25% of subjects. Both regimens were well tolerated. These data show that the administration of cisplatin-based second-line chemotherapy to patients with symptomatic advanced NSCLC may be useful. [ABSTRACT FROM AUTHOR]
- Published
- 1992
- Full Text
- View/download PDF
42. Phase II study of mitomycin C, etoposide and vindesine in metastatic stage IV non-small-cell lung cancer.
- Author
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Gridelli, Cesare, Pepe, Rosario, Palmeri, Sergio, Iacobelli, Stefano, Gentile, Maria, Gebbia, Vittorio, Garufi, Carlo, Airoma, Giuseppe, Palmieri, Giovannella, Russo, Anna, Incoronato, Pasquale, Placido, Sabino, Perrone, Francesco, Basilico, Luigi, Rausa, Luciano, Ferrante, Giovanni, Bianco, Angelo, Gridelli, C, Pepe, R, and Palmeri, S
- Subjects
ALKALOIDS ,ANTINEOPLASTIC agents ,CLINICAL trials ,CLINICAL drug trials ,ETOPOSIDE ,LUNG cancer ,LUNG tumors ,METASTASIS ,TIME ,TUMOR classification ,DISEASE remission ,MITOMYCINS - Abstract
A total of 72 patients with metastatic stage IV non-small-cell lung cancer (NSCLC) were treated with combination chemotherapy comprising the MEV regimen (mitomycin C, 8 mg/m2 given i.v. on day 1; etoposide, 100 mg/m2 given i.v. on days 1-3; and vindesine, 3 mg/m2 given i.v. on day 1; treatment repeated every 3 weeks). In 65 evaluable patients, the objective response rate was 37% (complete responses, 4.7%; partial responses, 32.3%). The median survival was 7.6 months for all patients. The treatment was very well tolerated. MEV proved to be an active and non-toxic regimen for the treatment of metastatic NSCLC. [ABSTRACT FROM AUTHOR]
- Published
- 1991
- Full Text
- View/download PDF
43. Turbulence Environment Characterization
- Author
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AVCO EVERETT RESEARCH LAB INC EVERETT MA, Miller, M G, Zieske, P L, Sofia, A J, Pepe, R J, AVCO EVERETT RESEARCH LAB INC EVERETT MA, Miller, M G, Zieske, P L, Sofia, A J, and Pepe, R J
- Abstract
This report contains discussions of a variety of activities and results relative to the characterization of atmospheric turbulence and its effects on optical propagation at the DARPA AMOS Observatory on Maui, Hawaii. Work carried out during this reporting period has included: (1) deployment and testing of new and/or modified instrumentation; (2) routine data collection; (3) special experiments for instrument characterization and calibration, and, (4) theoretical and statistical analysis of the resulting data., Sponsored in part by DARPA.
- Published
- 1977
44. NANOG: ITS ROLE IN THE TKI RESISTANCE OBSERVED IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA
- Author
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Caruso, S., Errichiello, S., Pisano, I., Quintarelli, C., BIAGIO DE ANGELIS, Izzo, B., Muccioli, G., Pugliese, M., Della Pepe, R., Musella, F., Del Prete, C., Visconti, R., Galdiero, A., Cacciapuoti, V., Siciliano, M., Pane, F., FONDAZIONE FERRARA STORTI, Caruso, Simona, Errichiello, Santa, Pisano, Ida, Quintarelli, Concetta, B. De, Angeli, Izzo, Barbara, G., Muccioli, M., Pugliese, R. Della, Pepe, F., Musella, C. Del, Prete, R., Visconti, A., Galdiero, V., Cacciapuoti, M., Siciliano, and Pane, Fabrizio
- Abstract
Treatment of patients with Chronic Myeloid Leukemia in chronic phase (CML-CP) with tyrosine kinase inhibitors (TKIs) showed a substantially improving of patient life expectancy. However,it is becoming evident that persistent leukemic stem cells, which are in-sensitive to TKIs in their quiescent state, can lead to CML recurring.Nanog is a pluripotency gene associated to a vital role in neoplasia, correlating with cell proliferation, clonogenic growth, tumorigenicity, and therapeutic resistance. Our group carried out microarray experiments on Ph+ KCL22 cell line with a sensible (Kcl22-S) or resistant (Kcl22-R) phenotype to Imatinib (Ima). The gene expression of Nanog was significantly increased in the Kcl22-R. Thus, we sought to investigate the role of Nanog in the TKI resistance observed in patients with CML-CP. Methods: Real Time RT-PCR (RT-qPCR) for the expression of Nanog was con- ducted on Ph+ K562 cell line treated with increasing doses of Ima. Western blotting (WB) analysis was conducted for the protein expression of Nanog on K562 cells treated with 5uM Ima. RNA was purified from mononuclear cells of 27 CML patients at diagnosis and after 3 months of TKI treatment. Patients were monitored by RT-qPCR for the expres- sion of the fusion BCR-ABL mRNA. RT-qPCR for the expression of Nanog, was conducted. RT-qPCR results were normalized by the ex- pression of Gus mRNA (Normalized mRNA copy Number: NCN). Re- sults: We observed a significant increase of Nanog mRNA expression in K562 cells treated with 0.5 uM of Imatinib. Moreover, we were also able to observe a significant increase of Nanog protein expression in K562 cells treated with 1-5uM Imatinib by WB. In peripheral blood samples of CML patients at diagnosis, we observed a significant higher mRNA expression of Nanog in No-Optimal Responder compared to Optimal Responder patients (NANOg mRNA: 0.3±0.25 NCN by GUS mRNA vs 0.6±0.7 NCN by GUS mRNA) Conclusions and Summary: These data sug- gest that the expression analysis of Nanog at CML patient baseline, may assist in the early prediction of molecular response in patients treated with TKI. Further studies are ongoing to functionally evaluate whether Nanog is regulated by endogenous or exogenous signals in leukemic cells and evaluate the role of Nanog stemness power in induction of trans- formation of hematopoietic stem cell.
45. Obtaining F1 hybrids from the genetic material of landrace bell artichokes, cleaned up and selected
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GIUSEPPE ROFRANO, Trotta, N., Pepe, R., Pagnotta, M. A., and Saccardo, F.
46. Towards a modular approach for unstructured shock-fitting
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Pepe, R., Bonfiglioli, A., Renato Paciorri, Lani, A., Mena, J. G., and Olliver-Gooch, C. F.
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Thermochemical nonequilibrium ,Nitrogen ,Shock-capturing ,Circular cylinders ,Unstructured meshes ,Computational fluid dynamics ,Shock-fitting ,Hypersonic flow ,Computational mechanics ,Von Karman ,Algorithms, Circular cylinders, Computational mechanics, Hypersonic flow, Nitrogen ,Modular approach, Shock-capturing, Shock-fitting, Thermo-chemical nonequilibrium flow, Thermochemical nonequilibrium, Unstructured grid, Unstructured meshes, Von Karman ,Modular approach ,Unstructured grid ,Algorithms ,Thermo-chemical nonequilibrium flow
47. Different circumstances of the first venous thromboembolism among younger or older heterozygous carriers of the G20210A polymorphism in the prothrombin gene
- Author
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Stefano, V., Rossi, E., Paciaroni, K., D Orazio, A., Cina, G., Marchitelli, E., Pepe, R., and Giuseppe Leone
48. Comparison of tropisetron (ICS 205-930) with alizapride plus dexamethasone in the prevention of emesis induced by repeated cisplatin administration
- Author
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Lauria, R., Palmieri, G., Pepe, R., Airoma, G., Oncoronato, P., Leo, L., Alessandro Morabito, Pagan, M. G., Bianco, A. R., Lauria, Rossella, Palmieri, Giovannella, R., Pepe, G., Airoma, P., Incoronato, L., Leo, A., Morabito, M. G., Pagan, and A. R., Bianco
49. Tolerability and clinical efficacy of desmin in the treatment of superficial thrombovaricophlebitis
- Author
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Andreozzi, G. M., Signorelli, S., Di Pino, L., Martini, R., Marchitelli, E., Antonio Pinto, Romeo, S., Zamboni, V., Palazzini, E., Pepe, R., and Gloria, R.
50. Percutaneous retrieval of retained common bile duct stones
- Author
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Pepe, R. G., primary, Havrilla, T. R., additional, and Meaney, T. F., additional
- Published
- 1977
- Full Text
- View/download PDF
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