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8 results on '"Perets, Galit"'

1. The role of additional chemotherapy prior to autologous HCT in patients with relapse/refractory DLBCL in partial remission—A retrospective multicenter study

Author

Shargian, Liat, primary, Amit, Odelia, additional, Bernstine, Hanna, additional, Gurion, Ronit, additional, Gafter‐Gvili, Anat, additional, Rozovski, Uri, additional, Pasvolsky, Oren, additional, Perets, Galit, additional, Horowitz, Netanel A., additional, Halloun, Jabour, additional, Perry, Chava, additional, Avivi, Irit, additional, Raanani, Pia, additional, Yeshurun, Moshe, additional, and Ram, Ron, additional

Published
2022
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2. The role of additional chemotherapy prior to autologous HCT in patients with relapse/refractory DLBCL in partial remission—A retrospective multicenter study.

Author

Shargian, Liat, Amit, Odelia, Bernstine, Hanna, Gurion, Ronit, Gafter‐Gvili, Anat, Rozovski, Uri, Pasvolsky, Oren, Perets, Galit, Horowitz, Netanel A., Halloun, Jabour, Perry, Chava, Avivi, Irit, Raanani, Pia, Yeshurun, Moshe, and Ram, Ron

Subjects
DISEASE relapse, DIFFUSE large B-cell lymphomas, STEM cell transplantation, HEMATOPOIETIC stem cell transplantation, SALVAGE therapy, PROGRESSION-free survival
Abstract

Objectives: To evaluate the role of additional chemotherapy before autologous hematopoietic cell transplantation (HCT) in patients with relapse/refractory diffuse large B‐cell lymphoma (DLBCL) who achieve partial remission following first salvage therapy. Methods: We conducted a multicenter retrospective study of all adult patients with DLBCL who underwent HCT between 2008 and 2020 and achieved partial response (PR) after the first salvage and were either referred directly to HCT (n = 47) or received additional salvage therapy before HCT (n = 22). Results: Post‐HCT CR rate and progression‐free survival were comparable between the two groups (66% vs. 68%, p =.86 and median not reached vs. 10.2 months [95% confidence interval, CI 7.1–12.3], p =.27, respectively). Median overall survival (OS) and estimated 3‐year OS favored patients who were directly referred to HCT (105.8 [95% CI 63–148] months vs. 14.5 [95% CI 0–44] months, p =.035, and 65% [95% CI 51%–75%] vs. 40% [95% CI 21%–53%], p =.035, respectively). In Cox regression model, while International Prognostic Index and primary refractory versus relapse disease did not impact OS, allocation to a second salvage regimen and older age were both associated with inferior survival (hazard ratio [HR] = 2.57 95% CI 1.1–5.8, p =.023 and HR = 1.04 95% CI 0.99–1.2, p =.064, respectively). Conclusions: Referring patients with chemotherapy‐sensitive disease in PR directly to HCT is associated with better OS compared to those receiving additional lines of treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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5. Venetoclax Is Safe and Efficacious in Relapsed/ Refractory AML

Author

Ganzel, Chezi, primary, Ram, Ron, additional, Gural, Alexander, additional, Wolach, Ofir, additional, Gino-Moor, Sharon, additional, Vainstein, Vladimir, additional, Nachmias, Boaz, additional, Apel, Arie, additional, Koren-Michowitz, Maya, additional, Pasvolsky, Oren, additional, Yerushalmi, Ronit, additional, Danylesko, Ivetta, additional, Cohen, Yoseph, additional, Perets, Galit, additional, Moshe, Yakir, additional, Zektzer, Miri, additional, Yeganeh, Shay, additional, Rowe, Jacob M., additional, and Ofran, Yishai, additional

Published
2019
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6. Radiation-Free Protocol for Patients with Acute Lymphoblastic Leukemia and Mixed Phenotype Acute Leukemia Undergoing Induction Chemotherapy and Allogeneic Hematopoietic Cell Transplantation - a Multicenter Historical Prospective Study

Author

Amit, Odelia, primary, Bar-On, Yael, additional, Avivi, Irit, additional, Zuckerman, Tsila, additional, Perets, Galit, additional, Henig, Israel, additional, Levi, Itai, additional, Yehudai-Ofir, Dana, additional, Harlev, Shimrit Ringelstein, additional, and Ram, Ron, additional

Published
2019
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7. Is the Achievement of Pre-Autologous Transplant CR Necessary Indeed in Refractory/ Relapsed DLBCL Patients? a Retrospective Multicenter Study

Author

Shargian-Alon, Liat, primary, Bernstine, Hanna, additional, Perets, Galit, additional, Gurion, Ronit, additional, Gafter-Gvili, Anat, additional, Pasvolsky, Oren, additional, Navon Sela, Michal, additional, Perry, Chava, additional, Avivi, Irit, additional, Amit, Odelia, additional, Raanani, Pia, additional, Ram, Ron, additional, and Yeshurun, Moshe, additional

Published
2019
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