Search

Your search keyword '"Perfect, Leo W."' showing total 9 results
Start Over Author "Perfect, Leo W."
9 results on '"Perfect, Leo W."'

1. Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Author

Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, and Hannon, Eilis

Published
2021
Full Text
View/download PDF

2. Additional file 3 of Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Author

Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, and Hannon, Eilis

Abstract

Additional file 3: Fig. S1. Histogram of age distribution. Chronological age of the fetal samples measured in days post-conception in A) training data, B) testing data and C) validation data.

Published
2021
Full Text
View/download PDF

3. Additional file 1 of Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Author

Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, and Hannon, Eilis

Subjects
embryonic structures
Abstract

Additional file 1: Table S1. Summary of fetal, adult and cellular datasets.

Published
2021
Full Text
View/download PDF

4. Additional file 2 of Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Author

Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, and Hannon, Eilis

Abstract

Additional file 2: Table S2. Intercept and coefficients of the Fetal Brain Clock.

Published
2021
Full Text
View/download PDF

5. Additional file 4 of Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Author

Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, and Hannon, Eilis

Abstract

Additional file 4: Fig. S2. Comparison of predictions from the four DNAm clocks in the training data (n = 193). Shown are scatterplots comparing chronological age (x-axis; days post-conception) against predicted epigenetic age (y-axis; days post-conception) for A Fetal Brain Clock (FBC); B Horvath’s Multi Tissue Clock (MTC); C Knight’s Gestational Age Clock (GAC); D Lee’s Control Placental Clock (CPC) in the data used for training of the FBC. Where necessary, predicted age was converted to days post-conception. The black line indicates the identity line of chronological and predicted epigenetic age and represents a perfect prediction. Two statistics were calculated to evaluate the precision of each DNAm clock: Pearson’s correlation coefficient (r) and the root mean squared error (RMSE).

Published
2021
Full Text
View/download PDF

6. Novel Epigenetic Clock for Fetal Brain Development Predicts Fetal Epigenetic Age for iPSCs and iPSC-Derived Neurons.

Author

Steg, Leonard C, primary, Shireby, Gemma L, additional, Imm, Jennifer, additional, Davies, Jonathan P, additional, Flynn, Robert, additional, Namboori, Seema C, additional, Bhinge, Akshay, additional, Jeffries, Aaron R, additional, Burrage, Joe, additional, Neilson, Grant W.A., additional, Walker, Emma M, additional, Perfect, Leo W, additional, Price, Jack, additional, Bray, Nicholas L, additional, Cope, Emma L, additional, Jones, Kimberly M, additional, Allen, Nicholas D, additional, Pishva, Ehsan, additional, Mill, Jonathan, additional, Lunnon, Katie, additional, and Hannon, Eilis, additional

Published
2020
Full Text
View/download PDF

7. Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

Author

Steg, Leonard C., primary, Shireby, Gemma L., additional, Imm, Jennifer, additional, Davies, Jonathan P., additional, Franklin, Alice, additional, Flynn, Robert, additional, Namboori, Seema C., additional, Bhinge, Akshay, additional, Jeffries, Aaron R., additional, Burrage, Joe, additional, Neilson, Grant W. A., additional, Walker, Emma M., additional, Perfect, Leo W., additional, Price, Jack, additional, McAlonan, Grainne, additional, Srivastava, Deepak P., additional, Bray, Nicholas J., additional, Cope, Emma L., additional, Jones, Kimberly M., additional, Allen, Nicholas D., additional, Pishva, Ehsan, additional, Dempster, Emma L., additional, Lunnon, Katie, additional, Mill, Jonathan, additional, and Hannon, Eilis, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results