Search

Your search keyword '"Perfume toxicity"' showing total 1,401 results
Start Over Descriptor "Perfume toxicity"
1,401 results on '"Perfume toxicity"'

1. RIFM fragrance ingredient safety assessment, 2-methyl-5-phenylpentanol, CAS Registry Number 25634-93-9.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Consumer Product Safety, Pentanols toxicity, Pentanols chemistry, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

2. Update to RIFM fragrance ingredient safety assessment, octyl formate, CAS registry number 112-32-3.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, Toxicity Tests, No-Observed-Adverse-Effect Level, Consumer Product Safety, Perfume toxicity, Perfume chemistry, Formates toxicity, Formates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

3. Update to RIFM fragrance ingredient safety assessment, octyl acetate, CAS Registry Number 112-14-1.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, No-Observed-Adverse-Effect Level, Consumer Product Safety, Toxicity Tests, Endpoint Determination, Perfume toxicity, Perfume chemistry, Odorants, Acetates toxicity, Acetates chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

4. RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-1.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Furaldehyde toxicity, Furaldehyde analogs & derivatives, Furaldehyde chemistry, Endpoint Determination, Consumer Product Safety, Toxicity Tests, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

5. Update to RIFM fragrance ingredient safety assessment, hexyl butyrate, CAS Registry Number 2639-63-6.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Butyrates toxicity, Butyrates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

6. RIFM fragrance ingredient safety assessment, allyl α-ionone, CAS Registry Number 79-78-7.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Norisoprenoids toxicity, Norisoprenoids chemistry, Endpoint Determination, Consumer Product Safety, No-Observed-Adverse-Effect Level, Toxicity Tests, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

7. RIFM fragrance ingredient safety assessment, 4-isopropyl-1-methylcyclohexene, CAS registry number 29350-67-2.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Cyclohexenes toxicity, Cyclohexenes chemistry, Endpoint Determination, Databases, Chemical, Consumer Product Safety, Toxicity Tests, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

8. Update to RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-methyl-, CAS Registry number 94201-19-1.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Spiro Compounds toxicity, Spiro Compounds chemistry, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

9. Update to RIFM fragrance ingredient safety assessment, hexyl formate, CAS registry number 629-33-4.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, No-Observed-Adverse-Effect Level, Endpoint Determination, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Formates toxicity, Formates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

10. Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Butyrates toxicity, Butyrates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

11. Update to RIFM fragrance ingredient safety assessment, lauryl acetate, CAS Registry Number 112-66-3.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Acetates toxicity, Acetates chemistry, Toxicity Tests, No-Observed-Adverse-Effect Level, Endpoint Determination, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

12. Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-5.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, No-Observed-Adverse-Effect Level, Endpoint Determination, Consumer Product Safety, Perfume toxicity, Perfume chemistry, Odorants, Acetates toxicity, Acetates chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

13. RIFM fragrance ingredient safety assessment, 3-methyl-5-phenylpentanol, CAS Registry Number 55066-48-3.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, Consumer Product Safety, Toxicity Tests, Pentanols toxicity, Pentanols chemistry, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

14. Update to RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]decan-2-one, 8-ethyl-, trans-, CAS Registry Number 91069-40-8.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Endpoint Determination, No-Observed-Adverse-Effect Level, Toxicity Tests, Spiro Compounds toxicity, Spiro Compounds chemistry, Databases, Chemical, Consumer Product Safety, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

15. RIFM fragrance ingredient safety assessment, 7-isopropyl-1,4-dimethylazulene, CAS registry number 489-84-9.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Endpoint Determination, Consumer Product Safety, Toxicity Tests, No-Observed-Adverse-Effect Level, Azulenes, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

16. Update to RIFM fragrance ingredient safety assessment, p-mentha-1,8-dien-7-ol, CAS Registry Number 536-59-4.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Animals, Humans, Consumer Product Safety, Databases, Chemical, Endpoint Determination, Menthol toxicity, Menthol chemistry, Menthol analogs & derivatives, No-Observed-Adverse-Effect Level, Odorants, Risk Assessment, Toxicity Tests, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

17. Assessment of genotoxic potential of fragrance materials in the chicken egg assays.

Author

Thakkar Y, Kobets T, Api AM, Duan JD, and Williams GM

Subjects
Animals, Mutagens toxicity, Aldehydes toxicity, Ovum drug effects, Acrolein toxicity, Acrolein analogs & derivatives, Chickens, Micronucleus Tests methods, Mutagenicity Tests methods, DNA Damage drug effects, Perfume toxicity
Abstract

The genotoxic and clastogenic/aneugeneic potentials of four α,β-unsaturated aldehydes, 2-phenyl-2-butenal, nona-2-trans-6-cis-dienal, 2-methyl-2-pentenal, and p-methoxy cinnamaldehyde, which are used as fragrance materials, were assessed using the Chicken Egg Genotoxicity Assay (CEGA) and the Hen's egg micronucleus (HET-MN) assay, respectively. Selection of materials was based on their chemical structures and the results of their previous assessment in the regulatory in vitro and/or in vivo genotoxicity test battery. Three tested materials, 2-phenyl-2-butenal, nona-2-trans-6-cis-dienal, and 2-methyl-2-pentenal, were negative in both, CEGA and HET-MN assays. These findings were congruent with the results of regulatory in vivo genotoxicity assays. In contrast, p-methoxy cinnamaldehyde, which was also negative in the in vivo genotoxicity assays, produced evidence of DNA damage, including DNA strand breaks and DNA adducts in CEGA. However, no increase in the micronucleus formation in blood was reported in the HET-MN study. Such variation in responses between the CEGA and HET-MN assay can be attributed to differences in the dosing protocols. Pretreatment with a glutathione precursor, N-acetyl cysteine, negated positive outcomes produced by p-methoxy cinnamaldehyde in CEGA, indicating that difference in response observed in the chicken egg and rodent models can be attributed to rapid glutathione depletion. Overall, our findings support the conclusion that CEGA and/or HET-MN can be considered as a potential alternative to animal testing as follow-up strategies for assessment of genotoxic potential of fragrance materials with evidence of genotoxicity in vitro., (© 2024 Environmental Mutagenesis and Genomics Society.)

Published
2024
Full Text
View/download PDF

18. RIFM fragrance ingredient safety assessment, 3-(methylthio)hexyl acetate, CAS registry number 51755-85-2.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Endpoint Determination, Toxicity Tests, Consumer Product Safety, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Acetates toxicity, Acetates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

19. RIFM fragrance ingredient safety assessment, 5-(cis-3-hexenyl)dihydro-5-methyl-2(3H)furanone, CAS Registry Number 70851-61-5.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Furans toxicity, Furans chemistry, Consumer Product Safety, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

20. RIFM fragrance ingredient safety assessment, 2,2-dimethyl-3-phenylpropanol, CAS registry number 13351-61-6.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Animals, Humans, Consumer Product Safety, Databases, Chemical, Endpoint Determination, No-Observed-Adverse-Effect Level, Propanols toxicity, Propanols chemistry, Risk Assessment, Toxicity Tests, Odorants, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

21. RIFM fragrance ingredient safety assessment, geranyl linalool, CAS registry number 1113-21-9.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Odorants, Monoterpenes toxicity, Monoterpenes chemistry, Consumer Product Safety, Endpoint Determination, Toxicity Tests, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Acyclic Monoterpenes toxicity, Acyclic Monoterpenes chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

22. RIFM fragrance ingredient safety assessment, geranyl acetate, CAS registry number 105-87-3.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, Consumer Product Safety, Toxicity Tests, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Odorants, Acetates toxicity, Acetates chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

23. RIFM fragrance ingredient safety assessment, o-phenyl anisole, CAS registry number 86-26-0.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Consumer Product Safety, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Anisoles toxicity, Anisoles chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

24. RIFM fragrance ingredient safety assessment, ionone (mixed isomers), CAS registry number 8013-90-9.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, Consumer Product Safety, Toxicity Tests, Isomerism, Databases, Chemical, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

25. RIFM fragrance ingredient safety assessment, ethyl salicylate, CAS Registry Number 118-61-6.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Endpoint Determination, Toxicity Tests, Consumer Product Safety, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants, Salicylates toxicity, Salicylates chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

26. Update to RIFM fragrance ingredient safety assessment, 4-phenyl-3-buten-2-ol, CAS registry number 17488-65-2.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Toxicity Tests, Endpoint Determination, Consumer Product Safety, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

27. Update to RIFM fragrance ingredient safety assessment, hexyl propionate, CAS Registry Number 2445-76-3.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Endpoint Determination, Consumer Product Safety, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants, Propionates toxicity, Propionates chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

28. Update to RIFM fragrance ingredient safety assessment, isopropyl acetate, CAS registry number 108-21-4.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Toxicity Tests, Endpoint Determination, Consumer Product Safety, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Acetates toxicity, Acetates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

29. Update to RIFM fragrance ingredient safety assessment, decyl acetate, CAS Registry Number 112-17-4.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Consumer Product Safety, Perfume toxicity, Perfume chemistry, Odorants, Acetates toxicity, Acetates chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

30. Update to RIFM fragrance ingredient safety assessment, α-butylcinnamaldehyde, CAS registry number 7492-44-6.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Acrolein toxicity, Acrolein chemistry, Acrolein analogs & derivatives, Toxicity Tests, Consumer Product Safety, Endpoint Determination, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

31. RIFM fragrance ingredient safety assessment, musk ketone, CAS registry number 81-14-1.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Ketones toxicity, Ketones chemistry, Endpoint Determination, Consumer Product Safety, Toxicity Tests, Fatty Acids, Monounsaturated toxicity, Fatty Acids, Monounsaturated chemistry, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

32. RIFM fragrance ingredient safety assessment, veratraldehyde, CAS Registry Number 120-14-9.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Animals, Humans, Consumer Product Safety, Databases, Chemical, Endpoint Determination, No-Observed-Adverse-Effect Level, Risk Assessment, Toxicity Tests, Odorants, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

33. RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 1048554.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Consumer Product Safety, Endpoint Determination, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Odorants analysis
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

34. Update to RIFM fragrance ingredient safety assessment, isopropyl butyrate, CAS Registry Number 638-11-9.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, Toxicity Tests, Databases, Chemical, No-Observed-Adverse-Effect Level, Consumer Product Safety, Perfume toxicity, Perfume chemistry, Butyrates toxicity, Butyrates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

35. RIFM fragrance ingredient safety assessment, trichloromethyl phenyl carbinyl acetate, CAS Registry number 90-17-5.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Acetates toxicity, Acetates chemistry, Endpoint Determination, Toxicity Tests, No-Observed-Adverse-Effect Level, Consumer Product Safety, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

36. RIFM fragrance ingredient safety assessment, 1,4-bis(ethoxymethyl)cyclohexane, CAS Registry Number 54889-63-3.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Endpoint Determination, Consumer Product Safety, Databases, Chemical, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Cyclohexanes toxicity, Cyclohexanes chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

37. RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-1.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Benzoates toxicity, Benzoates chemistry, Toxicity Tests, Endpoint Determination, Bridged Bicyclo Compounds toxicity, Bridged Bicyclo Compounds chemistry, Consumer Product Safety, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

38. RIFM fragrance ingredient safety assessment, 2-methyl-4-phenylpentanol, CAS registry number 92585-24-5.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Consumer Product Safety, Endpoint Determination, Pentanols toxicity, Pentanols chemistry, Toxicity Tests, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

39. RIFM fragrance ingredient safety assessment, 3-(2-oxopropyl)-2-pentylcyclopentanone, CAS Registry Number 40942-73-2.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Odorants, Cyclopentanes toxicity, Cyclopentanes chemistry, Endpoint Determination, Consumer Product Safety, Toxicity Tests, Databases, Chemical, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

40. RIFM fragrance ingredient safety assessment, tetrahydrogeranial, CAS Registry Number 5988-91-0.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Endpoint Determination, Toxicity Tests, Consumer Product Safety, Monoterpenes toxicity, Monoterpenes chemistry, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

41. RIFM fragrance ingredient safety assessment, 3-hexene, 1-[(2-methyl-2-propenyl)oxy]- (3Z)-, CAS Registry Number 292605-05-1.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Consumer Product Safety, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

42. Update to RIFM fragrance ingredient safety assessment, l-menthyl D-lactate, CAS registry number 59259-38-0.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Odorants, Toxicity Tests, Menthol toxicity, Menthol chemistry, Menthol analogs & derivatives, Endpoint Determination, Consumer Product Safety, No-Observed-Adverse-Effect Level, Lactates toxicity, Lactates chemistry, Databases, Chemical, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

43. RIFM fragrance ingredient safety assessment, piperonyl acetate, CAS registry number 326-61-4.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Odorants, Acetates toxicity, Acetates chemistry, Endpoint Determination, Toxicity Tests, Consumer Product Safety, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

44. RIFM fragrance ingredient safety assessment, nerolidyl acetate (isomer unspecified), CAS registry number 2306-78-7.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Odorants, Acetates toxicity, Acetates chemistry, Endpoint Determination, Consumer Product Safety, Toxicity Tests, No-Observed-Adverse-Effect Level, Sesquiterpenes toxicity, Sesquiterpenes chemistry, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

45. Update to RIFM fragrance ingredient safety assessment, α-propylphenethyl alcohol, CAS registry number 705-73-7.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Toxicity Tests, Endpoint Determination, No-Observed-Adverse-Effect Level, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

46. Update to RIFM fragrance ingredient safety assessment, (Z)-octadec-9-enol, CAS registry number 143-28-2.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Consumer Product Safety, Endpoint Determination, Toxicity Tests, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

47. RIFM fragrance ingredient safety assessment, 2-(4-methylphenoxy)ethanol, CAS Registry Number 15149-10-7.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Risk Assessment, Animals, Odorants, Endpoint Determination, Toxicity Tests, Consumer Product Safety, No-Observed-Adverse-Effect Level, Perfume toxicity, Perfume chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

48. RIFM fragrance ingredient safety assessment, phenethyl alcohol, CAS Registry Number 60-12-8.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Phenylethyl Alcohol toxicity, Phenylethyl Alcohol analogs & derivatives, Phenylethyl Alcohol chemistry, Endpoint Determination, Toxicity Tests, Consumer Product Safety, No-Observed-Adverse-Effect Level, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

49. RIFM fragrance ingredient safety assessment, cis-3-hexenal, CAS Registry Number 6789-80-6.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, No-Observed-Adverse-Effect Level, Toxicity Tests, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Odorants, Aldehydes toxicity, Aldehydes chemistry
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

50. Update to RIFM fragrance ingredient safety assessment, hexyl acetate, CAS registry number 142-92-7.

Author

Api AM, Bartlett A, Belsito D, Botelho D, Bruze M, Bryant-Freidrich A, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Dekant W, Deodhar C, Farrell K, Fryer AD, Jones L, Joshi K, Lapczynski A, Lavelle M, Lee I, Moustakas H, Muldoon J, Penning TM, Ritacco G, Sadekar N, Schember I, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, and Tokura Y

Subjects
Humans, Animals, Risk Assessment, Endpoint Determination, Toxicity Tests, No-Observed-Adverse-Effect Level, Consumer Product Safety, Databases, Chemical, Perfume toxicity, Perfume chemistry, Acetates toxicity, Acetates chemistry, Odorants
Abstract

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. RIFM staff are employees of the Research Institute for Fragrance Materials, Inc. (RIFM). The Expert Panel receives a small honorarium for time spent reviewing the subject work.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results