227 results on '"Perisic, Olga"'
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2. Making PI3K superfamily enzymes run faster
3. Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
4. Multifocal, multiphenotypic tumours arising from an MTORmutation acquired in early embryogenesis
5. Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
6. Activation of GCN2 by the ribosomal P-stalk
7. Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
8. Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors
9. Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis
10. Paradoxical dominant negative activity of an immunodeficiency-associated activatingPIK3R1variant
11. Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress
12. Structural insights into the activation of ataxiatelangiectasia mutated by oxidative stress.
13. Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
14. Molecular determinants of PI3Kγ-mediated activation downstream of G-protein—coupled receptors (GPCRs)
15. Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage
16. ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes
17. Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA)
18. The UBAP1 Subunit of ESCRT-I Interacts with Ubiquitin via a SOUBA Domain
19. Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34
20. Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism
21. Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit
22. A Tobacco DNA Binding Protein That Interacts with a Light-Responsive Box II Element
23. Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
24. Architecture of human Rag GTPase heterodimers and their complex with mTORC1
25. STRUCTURAL BIOLOGY: Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors
26. Author response: Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
27. Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
28. Structural insight into the ESCRT‐I/‐II link and its role in MVB trafficking
29. Binding of the PX domain of p47phox to phosphatidylinositol 3,4‐bisphosphate and phosphatidic acid is masked by an intramolecular interaction
30. ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes
31. Deuterium exchange mass spectrometry used to probe membrane recruitment of the common oncogene phosphoinositide 3-kinase (p110α): 377
32. Structural insights into phosphoinositide 3-kinase catalysis and signalling
33. Abstract IA10: Structure and dynamics of Rag heterodimers in a complex with mTORC1
34. Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma
35. Robotic nanolitre protein crystallisation at the MRC Laboratory of Molecular Biology
36. Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4
37. Phosphoinositide-specific phospholipase C delta1 activity toward micellar substrates, inositol 1,2-cyclic phosphate, and other water-soluble substrates: a sequential mechanism and allosteric activation
38. A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-(delta)1
39. Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C
40. Crystal structure of a mammalian phosphoinositide-specific phospholipase C-delta
41. ESCRT-II, an Endosome-Associated Complex Required for Protein Sorting: Crystal Structure and Interactions with ESCRT-III and Membranes
42. Sequential Mechanism and Allosteric Activation of Phosphoinositide-Specific Phospholipase C-δ1
43. Structural Basis for Arl1-Dependent Targeting of Homodimeric GRIP Domains to the Golgi Apparatus
44. PB1 Domain-Mediated Heterodimerization in NADPH Oxidase and Signaling Complexes of Atypical Protein Kinase C with Par6 and p62
45. Architecture of human Rag GTPase heterodimers and their complex with mTORC1
46. Tyrosine Residues in Phospholipase Cγ2 Essential for the Enzyme Function in B-cell Signaling
47. The Crystal Structure of the PX Domain from p40 phox Bound to Phosphatidylinositol 3-Phosphate
48. Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine
49. Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ
50. Mapping the Phospholipid-binding Surface and Translocation Determinants of the C2 Domain from Cytosolic Phospholipase A2
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