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303 results on '"Perkins, Sarah E"'

2. The smell of infection: Disease surveillance in insects using volatile organic compounds.

Author

Asiri, Ayman, Perkins, Sarah E., and Müller, Carsten T.

Subjects
*PUBLIC health surveillance, *INSECT diseases, *ENVIRONMENTAL monitoring, *CHEMICAL ecology, *VOLATILE organic compounds, *HONEYBEES
Abstract

Insects play crucial roles in nearly every ecosystem and provide a wide array of ecosystem services. However, both managed and wild insect populations face threats from parasites and pathogens, which require surveillance to mitigate.Current infectious disease surveillance methods for insects often involve invasive, time‐consuming and occasionally destructive techniques, such as manual inspections and molecular detection.Volatile organic compound (VOC) surveillance provides a real‐time, accurate and non‐invasive alternative for disease detection and has been well‐established in humans and livestock.Recent advances in sensor technology now allow for the development of in‐field VOC surveillance devices. This review explores the need for disease surveillance in insects and highlights recent advances of using VOCs for this purpose, focusing on honey bees as an example.We outline potential applications, challenges and future prospects of using VOCs for insect disease surveillance, providing examples of how this technology could be globally applied to mitigate the impacts of disease in a range of insect systems. [ABSTRACT FROM AUTHOR]

Published
2025
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4. Temporal niche partitioning as a potential mechanism for coexistence in two sympatric mesopredator sharks.

Author

Cook, Neil D., Jenkins, Abbie, Perry, Sarah L., Perkins, Sarah E., and Cable, Jo

Subjects
OCEAN zoning, PREDATORY aquatic animals, MARINE parks & reserves, BLUE economy, ENDANGERED species, MARINE biodiversity
Abstract

Global marine biodiversity declines require bold and ambitious plans to safeguard ecosystem services. Overfishing, habitat loss and projected climate impacts have yielded deleterious effects on marine predators, in particular, driving increasing threat of extinction for many shark species with implications for ecosystem health. Identifying and protecting critical habitat areas for sharks is fundamental to their protection, and may allow for species recovery. Here we use baited remote underwater video stations to investigate spatial and temporal patterns of habitat use by sharks in a Special Area of Conservation (SAC) that is centrally important to the regional blue economy in the UK, the Cardigan Bay SAC. Our results show heterogeneous spatial habitat use and temporal trends in habitat sharing between smallspotted catsharks Scyliorhinus canicula and nursehounds S. stellaris. Nearshore reef habitats are substantially more important than non-reef habitats for both species. The relative abundance of each species, however, is roughly inversely seasonally proportional, with S. canicula and S. stellaris relative abundance highest in March and September, respectively. Temporal niche partitioning may be an important mechanism in marine systems, but has not been widely investigated in sympatric shark communities. These findings are directly relevant for ongoing development of the Welsh Marine Evidence Strategy (2019-2025) and the Welsh National Marine Plan, particularly to inform spatial planning to strengthen the role of SAC management design in protecting important shark areas. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Tumorgrafts as In Vivo Surrogates for Women with Ovarian Cancer

Author

Weroha, S John, Becker, Marc A, Enderica-Gonzalez, Sergio, Harrington, Sean C, Oberg, Ann L, Maurer, Matthew J, Perkins, Sarah E, AlHilli, Mariam, Butler, Kristina A, McKinstry, Sarah, Fink, Stephanie, Jenkins, Robert B, Hou, Xiaonan, Kalli, Kimberly R, Goodman, Karin M, Sarkaria, Jann N, Karlan, Beth Y, Kumar, Amanika, Kaufmann, Scott H, Hartmann, Lynn C, and Haluska, Paul

Subjects
Rare Diseases, Ovarian Cancer, Orphan Drug, Cancer, Good Health and Well Being, Adult, Aged, Aged, 80 and over, Animals, Biomarkers, Tumor, Chromosome Aberrations, Cluster Analysis, Comparative Genomic Hybridization, Disease Models, Animal, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Graft Survival, Heterografts, Humans, Mice, Middle Aged, Neoplasm Grading, Neoplasm Metastasis, Neoplasm Staging, Ovarian Neoplasms, Ultrasonography, Xenograft Model Antitumor Assays, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

PurposeOvarian cancer has a high recurrence and mortality rate. A barrier to improved outcomes includes a lack of accurate models for preclinical testing of novel therapeutics.Experimental designClinically relevant, patient-derived tumorgraft models were generated from sequential patients and the first 168 engrafted models are described. Fresh ovarian, primary peritoneal, and fallopian tube carcinomas were collected at the time of debulking surgery and injected intraperitoneally into severe combined immunodeficient mice.ResultsTumorgrafts demonstrated a 74% engraftment rate with microscopic fidelity of primary tumor characteristics. Low-passage tumorgrafts also showed comparable genomic aberrations with the corresponding primary tumor and exhibit gene set enrichment of multiple ovarian cancer molecular subtypes, similar to patient tumors. Importantly, each of these tumorgraft models is annotated with clinical data and for those that have been tested, response to platinum chemotherapy correlates with the source patient.ConclusionsPresented herein is the largest known living tumor bank of patient-derived, ovarian tumorgraft models that can be applied to the development of personalized cancer treatment.

Published
2014

21. A hierarchical approach to defining marine heatwaves

Author

Hobday, Alistair J., Alexander, Lisa V., Perkins, Sarah E., Smale, Dan A., Straub, Sandra C., Oliver, Eric C.J., Benthuysen, Jessica A., Burrows, Michael T., Donat, Markus G., Feng, Ming, Holbrook, Neil J., Moore, Pippa J., Scannell, Hillary A., Sen Gupta, Alex, and Wernberg, Thomas

Published
2016
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24. The presence of territorial damselfish predicts choosy client species richness at cleaning stations

Author

Dunkley, Katie, Whittey, Kathryn E, Ellison, Amy, Perkins, Sarah E, Cable, Jo, Herbert-Read, James E, Dunkley, Katie [0000-0002-6032-6577], Whittey, Kathryn E [0000-0002-1557-757X], Ellison, Amy [0000-0003-3885-6077], Perkins, Sarah E [0000-0002-7457-2699], Cable, Jo [0000-0002-8510-7055], Herbert-Read, James E [0000-0003-0243-4518], and Apollo - University of Cambridge Repository

Subjects
cleaner fish, mutualism, biological market theory, Elacatinus evelynae, partner choice, Animal Science and Zoology, ecological networks, Ecology, Evolution, Behavior and Systematics
Abstract

Mutualisms are driven by partners deciding to interact with one another to gain specific services or rewards. As predicted by biological market theory, partners should be selected based on the likelihood, quality, reward level, and or services each partner can offer. Third-party species that are not directly involved in the interaction, however, may indirectly affect the occurrence and or quality of the services provided, thereby affecting which partners are selected or avoided. We investigated how different clients of the sharknose goby (Elacatinus evelynae) cleaner fish were distributed across cleaning stations, and asked what characteristics, relating to biological market theory, affected this distribution. Through quantifying the visitation and cleaning patterns of client fish that can choose which cleaning station(s) to visit, we found that the relative species richness of visiting clients at stations was negatively associated with the presence of disruptive territorial damselfish at the station. Our study highlights, therefore, the need to consider the indirect effects of third-party species and their interactions (e.g., agonistic interactions) when attempting to understand mutualistic interactions between species. Moreover, we highlight how cooperative interactions may be indirectly governed by external partners.

Published
2022
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26. Supplementary Figure Legend from Tumorgrafts as In Vivo Surrogates for Women with Ovarian Cancer

Author

Weroha, S. John, primary, Becker, Marc A., primary, Enderica-Gonzalez, Sergio, primary, Harrington, Sean C., primary, Oberg, Ann L., primary, Maurer, Matthew J., primary, Perkins, Sarah E., primary, AlHilli, Mariam, primary, Butler, Kristina A., primary, McKinstry, Sarah, primary, Fink, Stephanie, primary, Jenkins, Robert B., primary, Hou, Xiaonan, primary, Kalli, Kimberly R., primary, Goodman, Karin M., primary, Sarkaria, Jann N., primary, Karlan, Beth Y., primary, Kumar, Amanika, primary, Kaufmann, Scott H., primary, Hartmann, Lynn C., primary, and Haluska, Paul, primary

Published
2023
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27. Supplementary Figures 1 - 4 from Tumorgrafts as In Vivo Surrogates for Women with Ovarian Cancer

Author

Weroha, S. John, primary, Becker, Marc A., primary, Enderica-Gonzalez, Sergio, primary, Harrington, Sean C., primary, Oberg, Ann L., primary, Maurer, Matthew J., primary, Perkins, Sarah E., primary, AlHilli, Mariam, primary, Butler, Kristina A., primary, McKinstry, Sarah, primary, Fink, Stephanie, primary, Jenkins, Robert B., primary, Hou, Xiaonan, primary, Kalli, Kimberly R., primary, Goodman, Karin M., primary, Sarkaria, Jann N., primary, Karlan, Beth Y., primary, Kumar, Amanika, primary, Kaufmann, Scott H., primary, Hartmann, Lynn C., primary, and Haluska, Paul, primary

Published
2023
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31. Demographic effects of road mortality on mammalian populations: a systematic review

Author

Moore, Lauren J, Petrovan, Silviu O, Bates, Adam J, Hicks, Helen L, Baker, Philip J, Perkins, Sarah E, Yarnell, Richard W, Moore, Lauren J [0000-0002-3562-8709], Petrovan, Silviu O [0000-0002-3984-2403], and Apollo - University of Cambridge Repository

Subjects
Mammals, roadkill, Ecology, Population Dynamics, genetic diversity, migration, survival, General Biochemistry, Genetics and Molecular Biology, study design, population growth, FOS: Biological sciences, Animals, Female, dispersal, General Agricultural and Biological Sciences, population persistence, Ecosystem
Abstract

Funder: Nottingham Trent University; Id: http://dx.doi.org/10.13039/100010016, Funder: People's Trust for Endangered Species; Id: http://dx.doi.org/10.13039/100018690, In light of rapidly expanding road networks worldwide, there is increasing global awareness of the growing amount of mammalian roadkill. However, the ways in which road mortality affects the population dynamics of different species remains largely unclear. We aimed to categorise the demographic parameters in mammalian populations around the world that are directly or indirectly affected by road mortality, as well as identify the most effective study designs for quantifying population-level consequences of road mortality. We conducted a comprehensive systematic review to synthesise literature published between 2000 and 2021 and out of 11,238 unique studies returned, 83 studies were retained comprising 69 mammalian species and 150 populations. A bias towards research-intensive countries and larger mammals was apparent. Although searches were conducted in five languages, all studies meeting the inclusion criteria were in English. Relatively few studies (13.3%) provided relevant demographic context to roadkill figures, hampering understanding of the impacts on population persistence. We categorised five direct demographic parameters affected by road mortality: sex- and age-biased mortality, the percentage of a population killed on roads per year (values up to 50% were reported), the contribution of roadkill to total mortality rates (up to 80%), and roadkill during inter-patch or long-distance movements. Female-biased mortality may be more prevalent than previously recognised and is likely to be critical to population dynamics. Roadkill was the greatest source of mortality for 28% of studied populations and both additive and compensatory mechanisms to roadkill were found to occur, bringing varied challenges to conservation around roads. In addition, intra-specific population differences in demographic effects of road mortality were common. This highlights that the relative importance of road mortality is likely to be context specific as the road configuration and habitat quality surrounding a population can vary. Road ecology studies that collect data on key life parameters, such as age/stage/sex-specific survival and dispersal success, and that use a combination of methods are critical in understanding long-term impacts. Quantifying the demographic impacts of road mortality is an important yet complex consideration for proactive road management.

Published
2023
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33. Which is a better predictor of plant traits: temperature or precipitation?

Author

Moles, Angela T., Perkins, Sarah E., Laffan, Shawn W., Flores-Moreno, Habacuc, Awasthy, Monica, Tindall, Marianne L., Sack, Lawren, Pitman, Andy, Kattge, Jens, Aarssen, Lonnie W., Anand, Madhur, Bahn, Michael, Blonder, Benjamin, Cavender-Bares, Jeannine, Cornelissen, J. Hans C., Cornwell, Will K., Díaz, Sandra, Dickie, John B., Freschet, Grégoire T., Griffiths, Joshua G., Gutierrez, Alvaro G., Hemmings, Frank A., Hickler, Thomas, Hitchcock, Timothy D., Keighery, Matthew, Kleyer, Michael, Kurokawa, Hiroko, Leishman, Michelle R., Liu, Kenwin, Niinemets, Ülo, Onipchenko, Vladimir, Onoda, Yusuke, Penuelas, Josep, Pillar, Valério D., Reich, Peter B., Shiodera, Satomi, Siefert, Andrew, Sosinski, Enio E., Soudzilovskaia, Nadejda A., Swaine, Emily K., Swenson, Nathan G., van Bodegom, Peter M., Warman, Laura, Weiher, Evan, Wright, Ian J., Zhang, Hongxiang, Zobel, Martin, and Bonser, Stephen P.

Published
2014
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36. Do invasive species perform better in their new ranges?

Author

Parker, John D., Torchin, Mark E., Hufbauer, Ruth A., Lemoine, Nathan P., Alba, Christina, Blumenthal, Dana M., Bossdorf, Oliver, Byers, James E., Dunn, Alison M., Heckman, Robert W., Hejda, Martin, Jarošík, Vojtěch, Kanarek, Andrew R., Martin, Lynn B., Perkins, Sarah E., Pyšek, Petr, Schierenbeck, Kristina, Schlöder, Carmen, van Klinken, Rieks, Vaughn, Kurt J., Williams, Wyatt, and Wolfe, Lorne M.

Published
2013

39. Indirect effects of parasites in invasions

Author

Dunn, Alison M., Torchin, Mark E., Hatcher, Melanie J., Kotanen, Peter M., Blumenthal, Dana M., Byers, James E., Coon, Courtney A.C., Frankel, Victor M., Holt, Robert D., Hufbauer, Ruth A., Kanarek, Andrew R., Schierenbeck, Kristina A., Wolfe, Lorne M., and Perkins, Sarah E.

Published
2012
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