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2. Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Author

Dmytriw, Adam A., Salim, Hamza, Musmar, Basel, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Dibas, Mahmoud, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Tutino, Vincent M., Ibrahim, Mohamed K., Mohammed, Marwa A., Imamoglu, Cetin, Bayrak, Ahmet, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer E., Ogilvie, Mark, Sporns, Peter, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Martinez-Gutierrez, Juan Carlos, Essibayi, Muhammed Amir, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Altschul, David, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M., Pereira, Vitor Mendes, Patel, Aman B., and Adeeb, Nimer

Published
2024
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4. International controlled study of revascularization and outcomes following COVID‐positive mechanical thrombectomy

Author

Dmytriw, Adam A, Ghozy, Sherief, Sweid, Ahmad, Piotin, Michel, Bekelis, Kimon, Sourour, Nader, Raz, Eytan, Vela‐Duarte, Daniel, Linfante, Italo, Dabus, Guilherme, Kole, Max, Martínez‐Galdámez, Mario, Nimjee, Shahid M, Lopes, Demetrius K, Hassan, Ameer E, Kan, Peter, Ghorbani, Mohammad, Levitt, Michael R, Escalard, Simon, Missios, Symeon, Shapiro, Maksim, Clarençon, Fréderic, Elhorany, Mahmoud, Tahir, Rizwan A, Youssef, Patrick P, Pandey, Aditya S, Starke, Robert M, Naamani, Kareem El, Abbas, Rawad, Mansour, Ossama Y, Galvan, Jorge, Billingsley, Joshua T, Mortazavi, Abolghasem, Walker, Melanie, Dibas, Mahmoud, Settecase, Fabio, Heran, Manraj KS, Kuhn, Anna L, Puri, Ajit S, Menon, Bijoy K, Sivakumar, Sanjeev, Mowla, Ashkan, D'Amato, Salvatore, Zha, Alicia M, Cooke, Daniel, Vranic, Justin E, Regenhardt, Robert W, Rabinov, James D, Stapleton, Christopher J, Goyal, Mayank, Wu, Hannah, Cohen, Jake, Turkel‐Parella, David, Xavier, Andrew, Waqas, Muhammad, Tutino, Vincent, Siddiqui, Adnan, Gupta, Gaurav, Nanda, Anil, Khandelwal, Priyank, Tiu, Cristina, Portela, Pere C, de la Ossa, Natalia Perez, Urra, Xabier, Lera, Mercedes, Arenillas, Juan F, Ribo, Marc, Requena, Manuel, Piano, Mariangela, Pero, Guglielmo, Sousa, Keith, Al‐Mufti, Fawaz, Hashim, Zafar, Nayak, Sanjeev, Renieri, Leonardo, Du, Rose, Aziz‐Sultan, Mohamed A, Liebeskind, David, Nogueira, Raul G, Abdalkader, Mohamad, Nguyen, Thanh N, Vigilante, Nicholas, Siegler, James E, Grossberg, Jonathan A, Saad, Hassan, Gooch, Michael R, Herial, Nabeel A, Rosenwasser, Robert H, Tjoumakaris, Stavropoula, Patel, Aman B, Tiwari, Ambooj, Jabbour, Pascal, and Investigators, North American Neurovascular COVID‐19 Consortium Society of Vascular and Interventional Neurology

Subjects
Biomedical and Clinical Sciences, Neurosciences, Clinical Sciences, Stroke, Clinical Research, Good Health and Well Being, Brain Ischemia, COVID-19, Cross-Sectional Studies, Endovascular Procedures, Humans, Male, Retrospective Studies, Thrombectomy, Treatment Outcome, large vessel occlusion, morbidity, mortality, stroke, North American Neurovascular COVID-19 (NAN-C) Consortium &amp, Society of Vascular and Interventional Neurology (SVIN) Investigators, Neurology & Neurosurgery, Clinical sciences
Abstract

Background and purposePrevious studies suggest that mechanisms and outcomes in patients with COVID-19-associated stroke differ from those in patients with non-COVID-19-associated strokes, but there is limited comparative evidence focusing on these populations. The aim of this study, therefore, was to determine if a significant association exists between COVID-19 status with revascularization and functional outcomes following thrombectomy for large vessel occlusion (LVO), after adjustment for potential confounding factors.MethodsA cross-sectional, international multicenter retrospective study was conducted in consecutively admitted COVID-19 patients with concomitant acute LVO, compared to a control group without COVID-19. Data collected included age, gender, comorbidities, clinical characteristics, details of the involved vessels, procedural technique, and various outcomes. A multivariable-adjusted analysis was conducted.ResultsIn this cohort of 697 patients with acute LVO, 302 had COVID-19 while 395 patients did not. There was a significant difference (p

Published
2022

5. Off-Label use of Woven EndoBridge device for intracranial brain aneurysm treatment: Modeling of occlusion outcome

Author

Dibas, Mahmoud, Spears, Julian, Sundararajan, Sri Hari, Al Balush, Ali, Vranic, Justin E., Inoue, Yasuaki, Mirshahi, Shervin, Alotaibi, Naif M., Harker, Pablo, Tutino, Vincent M., Sporns, Peter, Brehm, Alex, Essibayi, Muhammed Amir, Jabal, Mohamed Sobhi, Musmar, Basel, Adeeb, Nimer, Salim, Hamza, Aslan, Assala, Cancelliere, Nicole M., McLellan, Rachel M., Algin, Oktay, Ghozy, Sherief, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Carnevale, Joseph, Saliou, Guillaume, Mastorakos, Panagiotis, Naamani, Kareem El, Shotar, Eimad, Premat, Kevin, Möhlenbruch, Markus, Kral, Michael, Doron, Omer, Chung, Charlotte, Salem, Mohamed M, Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Shaikh, Hamza, Župančić, Vedran, Hafeez, Muhammad U., Catapano, Joshua, Waqas, Muhammad, Yavuz, Kivilcim, Gunes, Yasin Celal, Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Starke, Robert M., Hassan, Ameer, Ogilvie, Mark, Nguyen, Anh, Jones, Jesse, Brinjikji, Waleed, Nawka, Marie T., Psychogios, Marios, Ulfert, Christian, Diestro, Jose Danilo Bengzon, Pukenas, Bryan, Burkhardt, Jan-Karl, Huynh, Thien, Gutierrez, Juan Carlos Martinez, Sheth, Sunil A., Spiegel, Gary, Tawk, Rabih, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Nossek, Erez, Raz, Eytan, Killer-Oberfalzer, Monika, Griessenauer, Christoph J., Asadi, Hamed, Siddiqui, Adnan, Brook, Allan L., Haranhalli, Neil, Ducruet, Andrew F., Albuquerque, Felipe C., Regenhardt, Robert W., Stapleton, Christopher J., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A., Tjoumakaris, Stavropoula I., Clarençon, Frédéric, Limbucci, Nicola, Cuellar-Saenz, Hugo H., Jabbour, Pascal M, Pereira, Vitor Mendes, Patel, Aman B., Altschul, David, and Dmytriw, Adam A.

Published
2024
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7. Characteristics of a COVID-19 Cohort With Large Vessel Occlusion: A Multicenter International Study

Author

Jabbour, Pascal, Dmytriw, Adam A, Sweid, Ahmad, Piotin, Michel, Bekelis, Kimon, Sourour, Nader, Raz, Eytan, Linfante, Italo, Dabus, Guilherme, Kole, Max, Martínez-Galdámez, Mario, Nimjee, Shahid M, Lopes, Demetrius K, Hassan, Ameer E, Kan, Peter, Ghorbani, Mohammad, Levitt, Michael R, Escalard, Simon, Missios, Symeon, Shapiro, Maksim, Clarençon, Frédéric, Elhorany, Mahmoud, Vela-Duarte, Daniel, Tahir, Rizwan A, Youssef, Patrick P, Pandey, Aditya S, Starke, Robert M, Naamani, Kareem El, Abbas, Rawad, Hammoud, Bassel, Mansour, Ossama Y, Galvan, Jorge, Billingsley, Joshua T, Mortazavi, Abolghasem, Walker, Melanie, Dibas, Mahmoud, Settecase, Fabio, Heran, Manraj KS, Kuhn, Anna L, Puri, Ajit S, Menon, Bijoy K, Sivakumar, Sanjeev, Mowla, Ashkan, D'Amato, Salvatore, Zha, Alicia M, Cooke, Daniel, Goyal, Mayank, Wu, Hannah, Cohen, Jake, Turkel-Parrella, David, Xavier, Andrew, Waqas, Muhammad, Tutino, Vincent M, Siddiqui, Adnan, Gupta, Gaurav, Nanda, Anil, Khandelwal, Priyank, Tiu, Cristina, Portela, Pere C, de la Ossa, Natalia Perez, Urra, Xabier, de Lera, Mercedes, Arenillas, Juan F, Ribo, Marc, Requena, Manuel, Piano, Mariangela, Pero, Guglielmo, De Sousa, Keith, Al-Mufti, Fawaz, Hashim, Zafar, Nayak, Sanjeev, Renieri, Leonardo, Aziz-Sultan, Mohamed A, Nguyen, Thanh N, Feineigle, Patricia, Patel, Aman B, Siegler, James E, Badih, Khodr, Grossberg, Jonathan A, Saad, Hassan, Gooch, M Reid, Herial, Nabeel A, Rosenwasser, Robert H, Tjoumakaris, Stavropoula, and Tiwari, Ambooj

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Clinical Research, Brain Disorders, Stroke, Good Health and Well Being, Brain Ischemia, COVID-19, Cerebral Infarction, Humans, Retrospective Studies, Thrombectomy, Treatment Outcome, SARS-CoV-2, Central nervous system, Cerebrovascular disease, Hypercoagulable, Neurology & Neurosurgery, Clinical sciences, Biological psychology
Abstract

BackgroundThe mechanisms and outcomes in coronavirus disease (COVID-19)-associated stroke are unique from those of non-COVID-19 stroke.ObjectiveTo describe the efficacy and outcomes of acute revascularization of large vessel occlusion (LVO) in the setting of COVID-19 in an international cohort.MethodsWe conducted an international multicenter retrospective study of consecutively admitted patients with COVID-19 with concomitant acute LVO across 50 comprehensive stroke centers. Our control group constituted historical controls of patients presenting with LVO and receiving a mechanical thrombectomy between January 2018 and December 2020.ResultsThe total cohort was 575 patients with acute LVO; 194 patients had COVID-19 while 381 patients did not. Patients in the COVID-19 group were younger (62.5 vs 71.2; P < .001) and lacked vascular risk factors (49, 25.3% vs 54, 14.2%; P = .001). Modified thrombolysis in cerebral infarction 3 revascularization was less common in the COVID-19 group (74, 39.2% vs 252, 67.2%; P < .001). Poor functional outcome at discharge (defined as modified Ranklin Scale 3-6) was more common in the COVID-19 group (150, 79.8% vs 132, 66.7%; P = .004). COVID-19 was independently associated with a lower likelihood of achieving modified thrombolysis in cerebral infarction 3 (odds ratio [OR]: 0.4, 95% CI: 0.2-0.7; P < .001) and unfavorable outcomes (OR: 2.5, 95% CI: 1.4-4.5; P = .002).ConclusionCOVID-19 was an independent predictor of incomplete revascularization and poor outcomes in patients with stroke due to LVO. Patients with COVID-19 with LVO were younger, had fewer cerebrovascular risk factors, and suffered from higher morbidity/mortality rates.

Published
2022

8. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Knopman, Jared, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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10. Correction to: The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Dibas, Mahmoud, Ghozy, Sherief, Adeeb, Nimer, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H., Sweid, Ahmad, Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Saliou, Guillaume, Möhlenbruch, Markus, Regenhardt, Robert W., Vranic, Justin E., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Rabinov, James D., Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna L., Michelozzi, Caterina, Elens, Stéphanie, Starke, Robert M., Hassan, Ameer, Salehani, Arsalaan, Sporns, Peter, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Stapleton, Christopher J., Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth, Tjoumakaris, Stavropoula, Jared Knopman, Aziz-Sultan, Mohammad A., Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, and Patel, Aman B.

Published
2023
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15. Gamma Knife Radiosurgery for Posterior Cranial Fossa Meningioma

Author

La Camera, Alessandro, Arienti, Virginia, Berta, Luca, Brambilla, Maria Grazia, Leocata, Filippo, Mainardi, Hae Song, Monti, Angelo Filippo, Pero, Guglielmo, Picano, Marco, Longhi, Michele, editor, Motti, Enrico D. F., editor, Nicolato, Antonio, editor, and Picozzi, Piero, editor

Published
2021
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18. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., Diestro, Jose Danilo Bengzon, Dibas, Mahmoud, Phan, Kevin, Sweid, Ahmad, Cuellar-Saenz, Hugo H., Lay, Sovann V., Guenego, Adrien, Renieri, Leonardo, Al Balushi, Ali, Sundararajan, Sri Hari, Carnevale, Joseph, Saliou, Guillaume, Möhlenbruch, Markus, Vranic, Justin E., Rabinov, James D., Lylyk, Ivan, Foreman, Paul M., Vachhani, Jay A., Župančić, Vedran, Hafeez, Muhammad U., Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M., Abbas, Rawad, Inoue, Yasuaki, Capirossi, Carolina, Ren, Yifan, Schirmer, Clemens M., Piano, Mariangela, Kühn, Anna Luisa, Michelozzi, Caterina, Elens, Stéphanie, Regenhardt, Robert W., Ghozy, Sherief, Alotaibi, Naif M., Tjoumakaris, Stavropoula, Starke, Robert M., Lubicz, Boris, Panni, Pietro, Puri, Ajit S., Pero, Guglielmo, Griessenauer, Christoph J., Asadi, Hamed, Brooks, Mark, Maingard, Julian, Jhamb, Ashu, Siddiqui, Adnan, Ducruet, Andrew F., Albuquerque, Felipe C., Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Savardekar, Amey, Boddu, Srikanth, Knopman, Jared, Limbucci, Nicola, Chen, Karen S., Aziz-Sultan, Mohammad A., Stapleton, Christopher J., Jabbour, Pascal, Cognard, Christophe, Patel, Aman B., and Adeeb, Nimer

Published
2021
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19. The impact of postoperative aspirin in patients undergoing Woven EndoBridge: a multicenter, institutional, propensity score-matched analysis

Author

Dmytriw, Adam A, primary, Musmar, Basel, additional, Salim, Hamza, additional, Aslan, Assala, additional, Cancelliere, Nicole M, additional, McLellan, Rachel M, additional, Algin, Oktay, additional, Ghozy, Sherief, additional, Dibas, Mahmoud, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Carnevale, Joseph Anthony, additional, Saliou, Guillaume, additional, Mastorakos, Panagiotis, additional, El Naamani, Kareem, additional, Shotar, Eimad, additional, Premat, Kevin, additional, Möhlenbruch, Markus A, additional, Kral, Michael, additional, Doron, Omer, additional, Chung, Charlotte, additional, Salem, Mohamed M, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Shaikh, Hamza, additional, Župančić, Vedran, additional, Hafeez, Muhammad Ubaid, additional, Catapano, Joshua S, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Ibrahim, Mohamed K, additional, Mohammed, Marwa A, additional, Imamoglu, Cetin, additional, Bayrak, Ahmet, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Hasan, Zuha, additional, Starke, Robert M, additional, Hassan, Ameer E, additional, Ogilvie, Mark, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Brinjikji, Waleed, additional, Nawka, Marie Teresa, additional, Psychogios, Marios-Nikos, additional, Ulfert, Christian, additional, Diestro, Jose Danilo Bengzon, additional, Pukenas, Bryan, additional, Burkhardt, Jan Karl, additional, Huynh, Thien J, additional, Martinez-Gutierrez, Juan Carlos, additional, Essibayi, Muhammed Amir, additional, Sheth, Sunil A, additional, Spiegel, Gary, additional, Tawk, Rabih, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Nossek, Erez, additional, Raz, Eytan, additional, Killer-Oberpfalzer, Monika, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan H, additional, Brook, Allan L, additional, Altschul, David, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Regenhardt, Robert W, additional, Stapleton, Christopher J, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Tjoumakaris, Stavropoula I, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Cuellar, Hugo H, additional, Jabbour, Pascal M, additional, Pereira, Vitor M, additional, Patel, Aman B, additional, and Adeeb, Nimer, additional

Published
2024
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20. Efficacy of ADAPT with large-bore reperfusion catheter in anterior circulation acute ischemic stroke: a multicentric Italian experience

Author

Romano, Daniele Giuseppe, Frauenfelder, Giulia, Casseri, Tommaso, Piano, Mariangela, Vinci, Sergio, Comai, Alessio, Stecco, Alessandro, Causin, Francesco, Asteggiano, Francesco, Paolucci, Aldo, Comelli, Chiara, Giorgianni, Andrea, Cirillo, Luigi, Ganci, Giuseppe, Cioni, Samuele, Pitrone, Antonio, Pero, Guglielmo, Papa, Rosario, Muto, Mario, Saponiero, Renato, and Bracco, Sandra

Published
2020
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21. Transvenous approach for the treatment of direct carotid cavernous fistula following Pipeline embolization of cavernous carotid aneurysm: a report of two cases and review of the literature

Author

Lin, Li-Mei, Colby, Geoffrey P, Jiang, Bowen, Pero, Guglielmo, Boccardi, Edoardo, and Coon, Alexander L

Subjects
Brain Disorders, Stroke, Neurosciences, Rare Diseases, Cardiovascular, Aneurysm, Carotid Artery, Internal, Carotid-Cavernous Sinus Fistula, Cerebral Angiography, Diagnosis, Differential, Embolization, Therapeutic, Humans, Magnetic Resonance Angiography, Middle Aged, Vascular Surgical Procedures, Angiography, Catheter, Coil, Device, Clinical Sciences
Abstract

Flow diverters are increasingly used for the endovascular treatment of cerebral aneurysms. A rare complication from flow diversion is delayed aneurysm rupture, which can lead to carotid-cavernous fistula (CCF) in the setting of cavernous carotid aneurysms (CCAs). Direct CCFs pose unique management challenges, given the lack of transarterial access to the fistula. We present two cases of direct CCFs following treatment of CCAs with the Pipeline embolization device (PED). Case 1 was a middle-aged patient with a symptomatic 10 mm wide-necked left CCA. Six weeks after PED treatment the patient developed diplopia secondary to direct CCF. Case 2 was a middle-aged patient with a symptomatic 17 mm left CCA treated with PED. One-month follow-up angiography demonstrated a direct CCF. Both patients underwent successful coil embolization of the CCF through a transvenous approach. Direct CCF formation following PED deployment for CCA is a rare complication. Parent vessel sacrifice may be avoided with transvenous occlusion of the fistula.

Published
2014

22. Endovascular Treatment of Acute Basilar Artery Occlusion: Registro Endovascolare Lombardo Occlusione Basilar Artery (RELOBA) Study Group Experience

Author

Giorgianni, Andrea, Biraschi, Francesco, Piano, Mariangela, Mardighian, Dikran, Gasparotti, Roberto, Frigerio, Michele, Pero, Guglielmo, Quilici, Luca, Crispino, Mario, Pellegrino, Carlo, Pavia, Marco, Peroni, Roberto, Longoni, Marco, Cellerini, Martino, Lafe, Elvis, Remida, Paolo, Faragò, Giuseppe, Reganati, Paolo, Strocchi, Sabina, and Valvassori, Luca

Published
2018
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23. Thrombectomy for Distal, Medium Vessel Occlusions: A Consensus Statement on Present Knowledge and Promising Directions

Author

Saver, Jeffrey L., Chapot, Rene, Agid, Ronit, Hassan, Ameer, Jadhav, Ashutosh P., Liebeskind, David S., Lobotesis, Kyriakos, Meila, Dan, Meyer, Lukas, Raphaeli, Guy, Gupta, Rishi, Amista’, Pietro, Andsberg, Gunnar, Cagnazzo, Federico, Isalberti, Maurizio, Karabegovic, Sanja, Kollia, Kiriaki, Mangiafico, Salvatore, Mis, Marcin, Moreno, Antonio, Mudersbach, Paul von Weitzel, Nossek, Erez, Pero, Guglielmo, Piasecki, Piotr, Raz, Eytan, Reis, Joao, Rudnicka, Svetlana, Sinisalo, Matias, Spinetta, Marco, Stavngaard, Trine, Undren, Per, and Zamaro, Joaquin

Published
2020
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25. Intracranial Carotid Occlusions

Author

Pero, Guglielmo, primary, Dória, Hugo Mota, additional, Piano, Mariangela, additional, Macera, Antonio, additional, Quilici, Luca, additional, and Cervo, Amedeo, additional

Published
2023
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27. International controlled study of revascularization and outcomes following COVID-positive mechanical thrombectomy

Author

North American Neurovascular COVID-19 (NAN-C) Consortium &amp, Dmytriw, Adam A, Ghozy, Sherief, Sweid, Ahmad, Piotin, Michel, Bekelis, Kimon, Sourour, Nader, Raz, Eytan, Vela-Duarte, Daniel, Linfante, Italo, Dabus, Guilherme, Kole, Max, Martínez-Galdámez, Mario, Nimjee, Shahid M, Lopes, Demetrius K, Hassan, Ameer E, Kan, Peter, Ghorbani, Mohammad, Levitt, Michael R, Escalard, Simon, Missios, Symeon, Shapiro, Maksim, Clarençon, Fréderic, Elhorany, Mahmoud, Tahir, Rizwan A, Youssef, Patrick P, Pandey, Aditya S, Starke, Robert M, El Naamani, Kareem, Abbas, Rawad, Mansour, Ossama Y, Galvan, Jorge, Billingsley, Joshua T, Mortazavi, Abolghasem, Walker, Melanie, Dibas, Mahmoud, Settecase, Fabio, Heran, Manraj KS, Kuhn, Anna L, Puri, Ajit S, Menon, Bijoy K, Sivakumar, Sanjeev, Mowla, Ashkan, D'Amato, Salvatore, Zha, Alicia M, Cooke, Daniel, Vranic, Justin E, Regenhardt, Robert W, Rabinov, James D, Stapleton, Christopher J, Goyal, Mayank, Wu, Hannah, Cohen, Jake, Turkel-Parella, David, Xavier, Andrew, Waqas, Muhammad, Tutino, Vincent, Siddiqui, Adnan, Gupta, Gaurav, Nanda, Anil, Khandelwal, Priyank, Tiu, Cristina, Portela, Pere C, Perez de la Ossa, Natalia, Urra, Xabier, de Lera, Mercedes, Arenillas, Juan F, Ribo, Marc, Requena, Manuel, Piano, Mariangela, Pero, Guglielmo, De Sousa, Keith, Al-Mufti, Fawaz, Hashim, Zafar, Nayak, Sanjeev, Renieri, Leonardo, Du, Rose, Aziz-Sultan, Mohamed A, Liebeskind, David, Nogueira, Raul G, Abdalkader, Mohamad, Nguyen, Thanh N, Vigilante, Nicholas, Siegler, James E, Grossberg, Jonathan A, Saad, Hassan, Gooch, Michael R, Herial, Nabeel A, Rosenwasser, Robert H, Tjoumakaris, Stavropoula, Patel, Aman B, Tiwari, Ambooj, and Jabbour, Pascal

Subjects
North American Neurovascular COVID-19 (NAN-C) Consortium &amp, Male, Neurology & Neurosurgery, Endovascular Procedures, Clinical Sciences, Neurosciences, COVID-19, morbidity, mortality, stroke, Society of Vascular and Interventional Neurology (SVIN) Investigators, Brain Ischemia, Treatment Outcome, Cross-Sectional Studies, Good Health and Well Being, Clinical Research, large vessel occlusion, Humans, Thrombectomy, Retrospective Studies
Abstract

Background and purposePrevious studies suggest that mechanisms and outcomes in patients with COVID-19-associated stroke differ from those in patients with non-COVID-19-associated strokes, but there is limited comparative evidence focusing on these populations. The aim of this study, therefore, was to determine if a significant association exists between COVID-19 status with revascularization and functional outcomes following thrombectomy for large vessel occlusion (LVO), after adjustment for potential confounding factors.MethodsA cross-sectional, international multicenter retrospective study was conducted in consecutively admitted COVID-19 patients with concomitant acute LVO, compared to a control group without COVID-19. Data collected included age, gender, comorbidities, clinical characteristics, details of the involved vessels, procedural technique, and various outcomes. A multivariable-adjusted analysis was conducted.ResultsIn this cohort of 697 patients with acute LVO, 302 had COVID-19 while 395 patients did not. There was a significant difference (p

Published
2022

28. Flow Diverter Devices in the Treatment of Anterior Communicating Artery Region Aneurysms: Would the Regional Anatomy and the Aneurysm Location Affect the Outcomes?

Author

Piano, Mariangela, primary, Trombatore, Pietro, additional, Lozupone, Emilio, additional, Pero, Guglielmo, additional, Cervo, Amedeo, additional, Macera, Antonio, additional, Quilici, Luca, additional, Peschillo, Simone, additional, Valvassori, Luca, additional, and Boccardi, Edoardo, additional

Published
2022
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29. Transradial versus transfemoral access for embolization of intracranial aneurysms with the Woven EndoBridge device: a propensity score–matched study

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Assala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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30. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium

Author

Dmytriw, Adam A., primary, Dibas, Mahmoud, additional, Ghozy, Sherief, additional, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Phan, Kevin, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Tjoumakaris, Stavropoula, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, and Patel, Aman B., additional

Published
2022
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31. Cerebral hyperdensity on CT imaging (CTHD) post-reperfusion treatment in patients with acute cerebral stroke: understanding its clinical meaning

Author

Calloni, Sonia Francesca, Panni, Pietro, Calabrese, Francesca, Del Poggio, Anna, Roveri, Luisa, Squarza, Silvia, Pero, Guglielmo Carlo, Paolucci, Aldo, Filippi, Massimo, Falini, Andrea, Anzalone, Nicoletta, Calloni, Sonia Francesca, Panni, Pietro, Calabrese, Francesca, Del Poggio, Anna, Roveri, Luisa, Squarza, Silvia, Pero, Guglielmo Carlo, Paolucci, Aldo, Filippi, Massimo, Falini, Andrea, and Anzalone, Nicoletta

Subjects
Stroke, Brain parenchymal hyperdensities, Treatment Outcome, CT imaging, Reperfusion, Humans, Radiology, Nuclear Medicine and imaging, Reperfusion therapy, General Medicine, Anterior circulation stroke, Tomography, X-Ray Computed, Brain Ischemia, Retrospective Studies
Abstract

Objectives To investigate the clinical meaning of brain parenchymal computed-tomography hyperdensities (CTHD) in patients treated of anterior circulation acute stroke with reperfusion therapy.Methods Patients were retrospectively enrolled from three different hospitals. Brain CT scans were assessed at four time points: We recorded ASPECT scores of pre-treatment CTs, assessed ASPECT scores and the presence of CTHD on posttreatment CTs acquired within 24-30 h and 24-72 h, and examined a one-month CTs follow-up to determine the ischemic evolution of CTHD. We correlated the presence of CTHD with clinical and radiological data to define its predictive and prognostic factors.Results In total, 165 patients were evaluated. At post-treatment CTs acquired within 24-30 h, 68 (41%) patients showed the presence of CTHD. On post-treatment CTs acquired within 24-72 h, 43 (63%) of the CTHD showed hemorrhagic transformation. Sixty-five (95%) out of the 68 CTHD evolved in a final ischemic brain area. Multivariate statistical analysis identified puncture to recanalization time to be the only independent factors predicting the presence of CTHD (p = 0.045). The presence of CTHD at the first post-treatment CTs was an independent factor for clinical outcome determined with mRS scores at 3-month follow-up (p = 0.05). Outcomes were worse for hemorrhagic transformation at follow-up CTs compared to the ischemic evolution of the CTHD (p = 0.01).Conclusions The presence of CTHD at CTs imaging acquired within 24-30 h after reperfusion therapy is an independent prognostic factor of a worse clinical outcome, regardless of its ASPECT score at baseline CTs and of its hemorrhagic evolution.

Published
2021

32. Neutrophil–Lymphocyte ratio is associated with poor clinical outcome after mechanical thrombectomy in stroke in patients with COVID-19.

Author

Al-Mufti, Fawaz, Khandelwal, Priyank, Sursal, Tolga, Cooper, Jared B., Feldstein, Eric, Amuluru, Krishna, Moré, Jayaji M., Tiwari, Ambooj, Singla, Amit, Dmytriw, Adam A, Piano, Mariangela, Quilici, Luca, Pero, Guglielmo, Renieri, Leonardo, Limbucci, Nicola, Martínez-Galdámez, Mario, Schüller-Arteaga, Miguel, Galván, Jorge, Arenillas-Lara, Juan Francisco, and Hashim, Zafar

Subjects
COVID-19, NEUTROPHIL lymphocyte ratio, ISCHEMIC stroke, COVID-19 pandemic, THROMBECTOMY
Abstract

Background: The neutrophil–lymphocyte ratio (NLR) is emerging as an important biomarker of acute physiologic stress in a myriad of medical conditions, and is a confirmed poor prognostic indicator in COVID-19. Objective: We sought to describe the role of NLR in predicting poor outcome in COVID-19 patients undergoing mechanical thrombectomy for acute ischemic stroke. Methods: We analyzed NLR in COVID-19 patients with large vessel occlusion (LVO) strokes enrolled into an international 12-center retrospective study of laboratory-confirmed COVID-19, consecutively admitted between March 1, 2020 and May 1, 2020. Increased NLR was defined as ≥7.2. Logistic regression models were generated. Results: Incidence of LVO stroke was 38/6698 (.57%). Mean age of patients was 62 years (range 27–87), and mortality rate was 30%. Age, sex, and ethnicity were not predictive of mortality. Elevated NLR and poor vessel recanalization (Thrombolysis in Cerebral Infarction (TICI) score of 1 or 2a) synergistically predicted poor outcome (likelihood ratio 11.65, p =.003). Patients with NLR > 7.2 were 6.8 times more likely to die (OR 6.8, CI95% 1.2–38.6, p =.03) and almost 8 times more likely to require prolonged invasive mechanical ventilation (OR 7.8, CI95% 1.2–52.4, p =.03). In a multivariate analysis, NLR > 7.2 predicted poor outcome even when controlling for the effect of low TICI score on poor outcome (NLR p =.043, TICI p =.070). Conclusions: We show elevated NLR in LVO patients with COVID-19 portends significantly worse outcomes and increased mortality regardless of recanalization status. Severe neuro-inflammatory stress response related to COVID-19 may negate the potential benefits of successful thrombectomy. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Multicenter Study for the Treatment of Sidewall versus Bifurcation Intracranial Aneurysms with Use of Woven EndoBridge (WEB)

Author

Adeeb, Nimer, primary, Dibas, Mahmoud, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Kandregula, Sandeep, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Aslan, Assala, additional, Möhlenbruch, Markus, additional, Vranic, Justin E., additional, Regenhardt, Robert W., additional, Savardekar, Amey, additional, Mamilly, Ahmed, additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Parra Farinas, Carmen, additional, Tutino, Vincent M., additional, Inoue, Yasuaki, additional, Mirshahi, Shervin, additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Brehm, Alex, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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34. Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Author

Diestro, Jose Danilo Bengzon, primary, Dibas, Mahmoud, additional, Adeeb, Nimer, additional, Regenhardt, Robert W, additional, Vranic, Justin E, additional, Guenego, Adrien, additional, Lay, Sovann V, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Shotar, Eimad, additional, Premat, Kevin, additional, El Naamani, Kareem, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus A., additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Župančić, Vedran, additional, Hafeez, Muhammad U, additional, Rutledge, Caleb, additional, Rai, Hamid, additional, Tutino, Vincent M, additional, Mirshani, Shervin, additional, Ghozy, Sherief, additional, Harker, Pablo, additional, Alotaibi, Naif M, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Goren, Oded, additional, Piano, Mariangela, additional, Kuhn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Starke, Robert M, additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Nguyen, Anh, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Parra-Fariñas, Carmen, additional, Bres Bullrich, Maria, additional, Mayich, Michael, additional, Salem, Mohamed M, additional, Burkhardt, Jan-Karl, additional, Jankowitz, Brian T, additional, Domingo, Ricardo A, additional, Huynh, Thien, additional, Tawk, Rabih, additional, Ulfert, Christian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan, additional, Ducruet, Andrew F, additional, Albuquerque, Felipe C, additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth Reddy, additional, Stapleton, Christopher J, additional, Knopman, Jared, additional, Jabbour, Pascal, additional, Tjoumakaris, Stavropoula, additional, Clarençon, Frédéric, additional, Limbucci, Nicola, additional, Aziz-Sultan, Mohammad A, additional, Cuellar-Saenz, Hugo H, additional, Cognard, Christophe, additional, Patel, Aman B, additional, and Dmytriw, Adam A, additional

Published
2022
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35. Transradial Versus Transfemoral Access for Woven EndoBridge (WEB) Embolization of Intracranial Aneurysms: A Propensity-Score Matched Multicenter Study (P1-1.Virtual)

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Asala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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36. The Woven EndoBridge (WEB) device for the treatment of Intracranial Aneurysms: A Decade of Lessons Learned and Changes in Practice from the WorldwideWEB Consortium (P1-1.Virtual)

Author

Dibas, Mahmoud, primary, Adeeb, Nimer, additional, Diestro, Jose Danilo Bengzon, additional, Cuellar-Saenz, Hugo H., additional, Sweid, Ahmad, additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Aslan, Asala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W., additional, Vranic, Justin E., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Rabinov, James D., additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna L., additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Starke, Robert M., additional, Hassan, Ameer E., additional, Salehani, Arsalaan, additional, Sporns, Peter, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Asadi, Hamed, additional, Stapleton, Christopher J., additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A., additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Dmytriw, Adam A., additional

Published
2022
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37. Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Author

Adeeb, Nimer, primary, Dibas, Mahmoud, additional, Diestro, Jose Danilo Bengzon, additional, Phan, Kevin, additional, Cuellar-Saenz, Hugo H, additional, Sweid, Ahmad, additional, Lay, Sovann V, additional, Guenego, Adrien, additional, Aslan, Assala, additional, Renieri, Leonardo, additional, Sundararajan, Sri Hari, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Regenhardt, Robert W, additional, Vranic, Justin E, additional, Lylyk, Ivan, additional, Foreman, Paul M, additional, Vachhani, Jay A, additional, Župančić, Vedran, additional, Hafeez, Muhammad U, additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M, additional, Rabinov, James D, additional, Ren, Yifan, additional, Schirmer, Clemens M, additional, Piano, Mariangela, additional, Kuhn, Anna L, additional, Michelozzi, Caterina, additional, Elens, Stephanie, additional, Starke, Robert M, additional, Hassan, Ameer, additional, Salehani, Arsalaan, additional, Brehm, Alex, additional, MohammedAli, MajdEddin, additional, Jones, Jesse, additional, Psychogios, Marios, additional, Spears, Julian, additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S, additional, Pero, Guglielmo, additional, Griessenauer, Christoph J, additional, Asadi, Hamed, additional, Siddiqui, Adnan, additional, Ducruet, Andrew, additional, Albuquerque, Felipe C, additional, Du, Rose, additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Stapleton, Christopher J, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Aziz-Sultan, Mohammad A, additional, Limbucci, Nicola, additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B, additional, and Dmytriw, Adam A, additional

Published
2022
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38. Neutrophil–Lymphocyte ratio is associated with poor clinical outcome after mechanical thrombectomy in stroke in patients with COVID-19

Author

Al-Mufti, Fawaz, primary, Khandelwal, Priyank, additional, Sursal, Tolga, additional, Cooper, Jared B., additional, Feldstein, Eric, additional, Amuluru, Krishna, additional, Moré, Jayaji M., additional, Tiwari, Ambooj, additional, Singla, Amit, additional, Dmytriw, Adam A, additional, Piano, Mariangela, additional, Quilici, Luca, additional, Pero, Guglielmo, additional, Renieri, Leonardo, additional, Limbucci, Nicola, additional, Martínez-Galdámez, Mario, additional, Schüller-Arteaga, Miguel, additional, Galván, Jorge, additional, Arenillas-Lara, Juan Francisco, additional, Hashim, Zafar, additional, Nayak, Sanjeev, additional, Desousa, Keith, additional, Sun, Hai, additional, Agarwalla, Pankaj K., additional, Sudipta Roychowdhury, J, additional, Nourollahzadeh, Emad, additional, Prakash, Tannavi, additional, Xavier, Andrew R, additional, Diego Lozano, J, additional, Gupta, Gaurav, additional, Yavagal, Dileep R, additional, Elghanem, Mohammad, additional, Gandhi, Chirag D., additional, and Mayer, Stephan A., additional

Published
2022
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39. International Study of Intracranial Aneurysm Treatment Using Woven EndoBridge: Results of the WorldWideWEB Consortium

Author

Dmytriw, Adam A., primary, Diestro, Jose Danilo Bengzon, additional, Dibas, Mahmoud, additional, Phan, Kevin, additional, Sweid, Ahmad, additional, Cuellar-Saenz, Hugo H., additional, Lay, Sovann V., additional, Guenego, Adrien, additional, Renieri, Leonardo, additional, Al Balushi, Ali, additional, Sundararajan, Sri Hari, additional, Carnevale, Joseph, additional, Saliou, Guillaume, additional, Möhlenbruch, Markus, additional, Vranic, Justin E., additional, Harker, Pablo, additional, Rabinov, James D., additional, Lylyk, Ivan, additional, Foreman, Paul M., additional, Vachhani, Jay A., additional, Župančić, Vedran, additional, Hafeez, Muhammad U., additional, Rutledge, Caleb, additional, Waqas, Muhammad, additional, Tutino, Vincent M., additional, Abbas, Rawad, additional, Inoue, Yasuaki, additional, Capirossi, Carolina, additional, Ren, Yifan, additional, Schirmer, Clemens M., additional, Piano, Mariangela, additional, Kühn, Anna Luisa, additional, Michelozzi, Caterina, additional, Elens, Stéphanie, additional, Regenhardt, Robert W., additional, Ghozy, Sherief, additional, Alotaibi, Naif M., additional, Tjoumakaris, Stavropoula, additional, Starke, Robert M., additional, Lubicz, Boris, additional, Panni, Pietro, additional, Puri, Ajit S., additional, Pero, Guglielmo, additional, Griessenauer, Christoph J., additional, Ulfert, Christian, additional, Asadi, Hamed, additional, Brooks, Mark, additional, Maingard, Julian, additional, Jhamb, Ashu, additional, Siddiqui, Adnan, additional, Ducruet, Andrew F., additional, Albuquerque, Felipe C., additional, Kan, Peter, additional, Kalousek, Vladimir, additional, Lylyk, Pedro, additional, Savardekar, Amey, additional, Boddu, Srikanth, additional, Knopman, Jared, additional, Limbucci, Nicola, additional, Chen, Karen S., additional, Aziz-Sultan, Mohammad A., additional, Stapleton, Christopher J., additional, Jabbour, Pascal, additional, Cognard, Christophe, additional, Patel, Aman B., additional, and Adeeb, Nimer, additional

Published
2022
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40. Radiological outcomes for endovascular treatment of posterior communicating artery aneurysms: a retrospective multicenter study of the occlusion rate

Author

Scerrati, Alba, primary, Trevisi, Gianluca, primary, Sturiale, Carmelo Lucio, primary, Salomi, Francesco, primary, De Bonis, Pasquale, primary, Saletti, Andrea, primary, Mangiola, Annunziato, primary, Tomatis, Alberto, primary, Di Egidio, Vincenzo, primary, Vigo, Vera, primary, Pedicelli, Alessandro, primary, Valente, Iacopo, primary, Rustemi, Oriela, primary, Beggio, Giacomo, primary, Iannucci, Giuseppe, primary, Milonia, Luca, primary, Ricciardi, Luca, primary, Cervo, Amedeo, primary, Pero, Guglielmo, primary, and Piano, Mariangela, primary

Published
2021
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41. FRED Italian Registry: a multicenter experience with the flow re-direction endoluminal device for intracranial aneurysms

Author

Piano, Mariangela, Valvassori, Luca, Lozupone, Emilio, Pero, Guglielmo, Quilici, Luca, Boccardi Edoardo, Bergui M, Stura G, Guidetti G, Peschillo S, Isalberti M, Paolucci A, Bracco S, Cioni S, De Nicola M, Giannoni M, Comelli S, Comelli C, Castellan L, Allegretti L, Menozzi R, Saltarelli A, Caputo N, Resta M, Donatelli M, Pedicelli A, Causin F, Cester G, Cagliari E, Cavasin N, Cagliari G, Petralia B, Gallesio I, Briganti F, Tortora F, Natrella M, Papa R, Pitrone A, Di Paola F, Thyrion F, Lafe E, Ciceri E, Faragò G, Remida P, Padolecchia R, DiVenuto I, Scomazzoni F, Simionato F, Mangiafico S, Limbucci N, Lazzarotti G., Piano, Mariangela, Valvassori, Luca, Lozupone, Emilio, Pero, Guglielmo, Quilici, Luca, Boccardi, Edoardo, Bergui, M, Stura, G, Guidetti, G, Peschillo, S, Isalberti, M, Paolucci, A, Bracco, S, Cioni, S, De Nicola, M, Giannoni, M, Comelli, S, Comelli, C, Castellan, L, Allegretti, L, Menozzi, R, Saltarelli, A, Caputo, N, Resta, M, Donatelli, M, Pedicelli, A, Causin, F, Cester, G, Cagliari, E, Cavasin, N, Cagliari, G, Petralia, B, Gallesio, I, Briganti, F, Tortora, F, Natrella, M, Papa, R, Pitrone, A, Di Paola, F, Thyrion, F, Lafe, E, Ciceri, E, Faragò, G, Remida, P, Padolecchia, R, Divenuto, I, Scomazzoni, F, Simionato, F, Mangiafico, S, Limbucci, N, and Lazzarotti, G.

Subjects
MCA = middle cerebral artery, medicine.medical_specialty, ICA = internal carotid artery, AE = adverse event, endovascular procedures, FRED, FDD = flow diverter device, vascular disorders, Asymptomatic, 03 medical and health sciences, 0302 clinical medicine, Aneurysm, DSA = digital subtraction angiography, Modified Rankin Scale, Complete occlusion, medicine, FRED = flow re-direction endoluminal device, Adverse effect, AsE = asymptomatic event, SAE = serious AE, BA = basilar artery, TIA = transient ischemic attack, GDC = Guglielmi detachable coil, VA = vertebral artery, medicine.diagnostic_test, PCoA = posterior communicating artery, business.industry, endovascular procedure, Mortality rate, AChA = anterior choroidal artery, General Medicine, ICH = intracerebral hemorrhage, OKM = O’Kelly-Marotta, PICA = posterior inferior cerebellar artery, RROC = Raymond-Roy occlusion classification, SAH = subarachnoid hemorrhage, interventional neurosurgery, intracranial aneurysm, mRS = modified Rankin Scale, new device, medicine.disease, Surgery, 030220 oncology & carcinogenesis, Sac shrinkage, Angiography, medicine.symptom, business, 030217 neurology & neurosurgery
Abstract

OBJECTIVEThe introduction of flow-diverter devices (FDDs) has revolutionized the endovascular treatment of intracranial aneurysms. Here the authors present their Italian multicenter experience using the flow re-direction endoluminal device (FRED) in the treatment of cerebral aneurysms, evaluating both short- and long-term safety and efficacy of this device.METHODSBetween February 2013 and December 2014, 169 consecutive aneurysms treated using FRED in 166 patients were entered into this study across 30 Italian centers. Data collected included patient demographics, aneurysm location and characteristics, baseline angiography, adverse event and serious adverse event information, morbidity and mortality rates, and pre- and posttreatment modified Rankin Scale scores, as well as angiographic and cross-sectional CT/MRI follow-up at 3–6 months and/or 12–24 months per institutional standard of care. All images were reviewed and adjudicated by an independent core lab.RESULTSOf the 169 lesions initially entered into the study, 4 were later determined to be extracranial or nonaneurysmal by the core lab and were excluded, leaving 165 aneurysms in 162 patients treated in 163 procedures. Ninety-one (56.2%) patients were asymptomatic with aneurysms found incidentally. Of the 165 aneurysms, 150 (90.9%) were unruptured. One hundred thirty-four (81.2%) were saccular, 27 (16.4%) were fusiform/dissecting, and the remaining 4 (2.4%) were blister-like. One hundred thirty-seven (83.0%) arose from the anterior circulation.FRED deployment was impossible in 2/163 (1.2%) cases, and in an additional 4 cases (2.5%) the device was misdeployed. Overall mortality and morbidity rates were 4.3% and 7.3%, respectively, with rates of mortality and morbidity potentially related to FRED of up to 2.4% and 6.2%, respectively. Neuroimaging follow-up at 3–6 months showed complete or nearly complete occlusion of the aneurysm in 94% of cases, increasing to 96% at 12–24 months’ follow-up. Aneurysmal sac shrinkage was observed in 78% of assessable aneurysms.CONCLUSIONSThis preliminary experience using FRED for endovascular treatment of complex unruptured and ruptured aneurysms showed a high safety and efficacy profile that is comparable to those of other FDDs currently in use.

Published
2020

43. Incidence, Characteristics and Outcomes of Large Vessel Stroke in COVID-19 Cohort: An International Multicenter Study

Author

Khandelwal, Priyank, primary, Al-Mufti, Fawaz, additional, Tiwari, Ambooj, additional, Singla, Amit, additional, Dmytriw, Adam A, additional, Piano, Mariangela, additional, Quilici, Luca, additional, Pero, Guglielmo, additional, Renieri, Leonardo, additional, Limbucci, Nicola, additional, Martínez-Galdámez, Mario, additional, Schüller-Arteaga, Miguel, additional, Galván, Jorge, additional, Arenillas-Lara, Juan Francisco, additional, Hashim, Zafar, additional, Nayak, Sanjeev, additional, Desousa, Keith, additional, Sun, Hai, additional, Agarwalla, Pankaj K, additional, Nanda, Anil, additional, Roychowdhury, J Sudipta, additional, Nourollahzadeh, Emad, additional, Prakash, Tannavi, additional, Gandhi, Chirag D, additional, Xavier, Andrew R, additional, Lozano, J Diego, additional, Gupta, Gaurav, additional, and Yavagal, Dileep R, additional

Published
2021
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47. Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study

Author

Diestro, Jose Danilo Bengzon, Dibas, Mahmoud, Adeeb, Nimer, Regenhardt, Robert W, Vranic, Justin E, Guenego, Adrien, Lay, Sovann V, Renieri, Leonardo, Al Balushi, Ali, Shotar, Eimad, Premat, Kevin, El Naamani, Kareem, Saliou, Guillaume, Mo¨hlenbruch, Markus A., Lylyk, Ivan, Foreman, Paul M, Vachhani, Jay A, Župančić, Vedran, Hafeez, Muhammad U, Rutledge, Caleb, Rai, Hamid, Tutino, Vincent M, Mirshani, Shervin, Ghozy, Sherief, Harker, Pablo, Alotaibi, Naif M, Rabinov, James D, Ren, Yifan, Schirmer, Clemens M, Goren, Oded, Piano, Mariangela, Kuhn, Anna Luisa, Michelozzi, Caterina, Elens, Stephanie, Starke, Robert M, Hassan, Ameer, Salehani, Arsalaan, Nguyen, Anh, Jones, Jesse, Psychogios, Marios, Spears, Julian, Parra-Fariñas, Carmen, Bres Bullrich, Maria, Mayich, Michael, Salem, Mohamed M, Burkhardt, Jan-Karl, Jankowitz, Brian T, Domingo, Ricardo A, Huynh, Thien, Tawk, Rabih, Ulfert, Christian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S, Pero, Guglielmo, Griessenauer, Christoph J, Asadi, Hamed, Siddiqui, Adnan, Ducruet, Andrew F, Albuquerque, Felipe C, Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Boddu, Srikanth Reddy, Stapleton, Christopher J, Knopman, Jared, Jabbour, Pascal, Tjoumakaris, Stavropoula, Clarencon, Frédéric, Limbucci, Nicola, Aziz-Sultan, Mohammad A, Cuellar-Saenz, Hugo H, Cognard, Christophe, Patel, Aman B, and Dmytriw, Adam A

Abstract

BackgroundThe Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor tailored for bifurcation aneurysms. We aim to describe the degree of aneurysm occlusion at the latest follow-up, and the rate of complications of aneurysms treated with the WEB device stratified according to rupture status.MethodsOur data were taken from the WorldWideWeb Consortium, an international multicenter cohort including patients treated with the WEB device. Aneurysms were classified into two groups: ruptured and unruptured. We compared clinical and radiologic outcomes of both groups. Propensity score matching (PSM) was done to match according to age, gender, bifurcation, location, prior treatment, neck, height, dome width, daughter sac, incorporated branch, pretreatment antiplatelets, and last imaging follow-up.ResultsThe study included 676 patients with 691 intracranial aneurysms (529 unruptured and 162 ruptured) treated with the WEB device. The PSM analysis had 55 pairs. In both the unmatched (85.8% vs 84.3%, p=0.692) and matched (94.4% vs 83.3%, p=0.066) cohorts there was no significant difference in the adequate occlusion rate at the last follow-up. Likewise, there were no significant differences in both ischemic and hemorrhagic complications between the two groups. There was no documented aneurysm rebleeding after WEB device implantation.ConclusionThere was no significant difference in both the radiologic outcomes and complications between unruptured and ruptured aneurysms. Our findings support the feasibility of treatment of ruptured aneurysms with the WEB device.

Published
2023
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48. Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device

Author

Adeeb, Nimer, Dibas, Mahmoud, Diestro, Jose Danilo Bengzon, Phan, Kevin, Cuellar-Saenz, Hugo H, Sweid, Ahmad, Lay, Sovann V, Guenego, Adrien, Aslan, Assala, Renieri, Leonardo, Sundararajan, Sri Hari, Saliou, Guillaume, Mo¨hlenbruch, Markus, Regenhardt, Robert W, Vranic, Justin E, Lylyk, Ivan, Foreman, Paul M, Vachhani, Jay A, Župančić, Vedran, Hafeez, Muhammad U, Rutledge, Caleb, Waqas, Muhammad, Tutino, Vincent M, Rabinov, James D, Ren, Yifan, Schirmer, Clemens M, Piano, Mariangela, Kuhn, Anna L, Michelozzi, Caterina, Elens, Stephanie, Starke, Robert M, Hassan, Ameer, Salehani, Arsalaan, Brehm, Alex, MohammedAli, MajdEddin, Jones, Jesse, Psychogios, Marios, Spears, Julian, Lubicz, Boris, Panni, Pietro, Puri, Ajit S, Pero, Guglielmo, Griessenauer, Christoph J, Asadi, Hamed, Siddiqui, Adnan, Ducruet, Andrew, Albuquerque, Felipe C, Du, Rose, Kan, Peter, Kalousek, Vladimir, Lylyk, Pedro, Stapleton, Christopher J, Boddu, Srikanth, Knopman, Jared, Aziz-Sultan, Mohammad A, Limbucci, Nicola, Jabbour, Pascal, Cognard, Christophe, Patel, Aman B, and Dmytriw, Adam A

Abstract

BackgroundThe Woven EndoBridge (WEB) device has Food and Drug Administration approval for treatment of wide-necked intracranial bifurcation aneurysms. The WEB device has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes.ObjectiveTo compare angiographic and clinical outcomes after treatment of bifurcation aneurysms at various locations, including anterior communicating artery (AComA), anterior cerebral artery (ACA) bifurcation distal to AComA, basilar tip, internal carotid artery (ICA) bifurcation, and middle cerebral artery (MCA) bifurcation aneurysms using the WEB device.MethodsA retrospective cohort analysis was conducted at 22 academic institutions worldwide to compare treatment outcomes of patients with intracranial bifurcation aneurysms using the WEB device. Data include patient and aneurysm characteristics, procedural details, angiographic and functional outcomes, and complications.ResultsA total of 572 aneurysms were included. MCA (36%), AComA (35.7%), and basilar tip (18.9%) aneurysms were most common. The rate of adequate aneurysm occlusion was significantly higher for basilar tip (91.6%) and ICA bifurcation (96.7%) aneurysms and lower for ACA bifurcation (71.4%) and AComA (80.6%) aneurysms (p=0.04).ConclusionTo our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.

Published
2023
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49. Abstract P104: Incidence, Characteristics and Outcomes of Large Vessel Stroke in Covid-19: An International Multicenter Study

Author

Khandelwal, Priyank, primary, Al-Mufti, Fawaz, additional, Tiwari, Ambooj, additional, Singla, Amit, additional, Dmytriw, Adam A, additional, Piano, Mariangela, additional, Quilici, Luca, additional, Pero, Guglielmo, additional, Renieri, Leonardo, additional, Limbucci, Nicola, additional, Martinez-Galdamez, Mario, additional, Arenillas-Lara, Juan F, additional, Schuller, Miguel, additional, Galvan, Jorge, additional, Hashim, Zafar, additional, Nayak, Sanjeev, additional, DeSousa, Keith, additional, Sun, Hai, additional, Agarwalla, Pankaj K, additional, Nanda, Anil, additional, Roychowdhury, Sudipta, additional, Nourollahzadeh, Emad, additional, Prakash, Tannavi, additional, Efendizade, Aslan, additional, Gandhi, Chirag D, additional, Xavier, Andrew R, additional, Gupta, Gaurav, additional, and Yavagal, Dileep R, additional

Published
2021
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