Search

Your search keyword '"Perrella O"' showing total 201 results
Start Over Author "Perrella O"
Sorry, I don't understand your search. ×
201 results on '"Perrella O"'

4. A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis

Author

De Vita, S., Quartuccio, L., Isola, M., Mazzaro, C., Scaini, P., Lenzi, M., Campanini, M., Naclerio, C., Tavoni, A., Pietrogrande, M., Ferri, C., Mascia, M. T., Masolini, P., Zabotti, A., Maset, M., Roccatello, D., Zignego, A. L., Pioltelli, P., Gabrielli, A., Filippini, D., Perrella, O., Migliaresi, S., Galli, M., Bombardieri, S., and Monti, G.

Published
2012
Full Text
View/download PDF

12. Cardiac Tamponade and Heart Failure Due to Myopericarditis as a Presentation of Infection with the Pandemic H1N1 2009 Influenza A Virus

Author

Puzelli S, Buonaguro FM, Facchini M, Palmieri A, Calzoletti L, De Marco MA, Arace P, de Campora E, Esposito C, Cassone A, Rezza G, Donatelli I, Surveillance Group for Pandemic H1N1 2009 Influenza Virus in Italy, Campania H1N1 Task Force, Vaccari G, Spagnolo D, Fabiani C, Santangelo M, DE ROSA, GAETANO, BUCCELLI, CLAUDIO, De Giorgi V, Franco R, Perrella O, Cerrato F, Dolcini A, Paladini R, Testa R, Vitullo ME, Ferbo U., Puzelli, S, Buonaguro, Fm, Facchini, M, Palmieri, A, Calzoletti, L, De Marco, Ma, Arace, P, de Campora, E, Esposito, C, Cassone, A, Rezza, G, Donatelli, I, Surveillance Group for Pandemic H1N1 2009 Influenza Virus in, Italy, Campania H1N1 Task, Force, Vaccari, G, Spagnolo, D, Fabiani, C, Santangelo, M, DE ROSA, Gaetano, Buccelli, Claudio, De Giorgi, V, Franco, R, Perrella, O, Cerrato, F, Dolcini, A, Paladini, R, Testa, R, Vitullo, Me, and Ferbo, U.

Subjects
Microbiology (medical), medicine.medical_specialty, viruses, MYOCARDITIS, CHILDREN, Case Reports, medicine.disease_cause, Pericardial effusion, Pericardial Effusion, Virus, Pericarditis, Influenza A Virus, H1N1 Subtype, Internal medicine, Cardiac tamponade, Influenza, Human, Influenza A virus, Humans, Medicine, Child, Heart Failure, Microscopy, Myositis, Histocytochemistry, business.industry, Myocardium, Pericardial fluid, Heart, ADULTS, medicine.disease, Cardiac Tamponade, Heart failure, Cardiology, Pharynx, Female, business, Myopericarditis
Abstract

We describe a fatal case of myopericarditis presenting with cardiac tamponade in a previously healthy 11-year-old child. Pandemic H1N1 2009 influenza A virus sequences were identified in throat and myocardial tissues and pericardial fluid, suggesting damage of myocardial cells directly caused by the virus.

Published
2010

13. A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis

Author

De Vita, S, Quartuccio, L, Isola, M, Mazzaro, C, Scaini, P, Lenzi, M, Campanini, M, Naclerio, C, Tavoni, A, Pietrogrande, M, Ferri, C, Mascia, Mt, Masolini, P, Zabotti, A, Maset, M, Roccatello, D, Zignego, Al, Pioltelli, P, Gabrielli, A, Filippini, D, Perrella, O, Migliaresi, S, Galli, M, Bombardieri, Stefano, Monti, G., De Vita S, Quartuccio L, Isola M, Mazzaro C, Scaini P, Lenzi M, Campanini M, Naclerio C, Tavoni A, Pietrogrande M, Ferri C, Mascia MT, Masolini P, Zabotti A, Maset M, Roccatello D, Zignego AL, Pioltelli P, Gabrielli A, Filippini D, Perrella O, Migliaresi S, Galli M, Bombardieri S, and Monti G.

Subjects
rituximab, vasculiti, hemic and lymphatic diseases, cryoglobulinemic, macromolecular substances, cryoglobulinemia, vasculitis
Abstract

To conduct a long-term, prospective, randomized controlled trial evaluating rituximab (RTX) therapy for severe mixed cryoglobulinemia or cryoglobulinemic vasculitis (CV). RTX monotherapy represents a very good option for severe CV and can be maintained over the long term in most patients.

Published
2012

15. A randomized controlled trial of rituximab for treatment of severe cryoglobulinemic vasculitis

Author

De Vita, S, Quartuccio, L, Isola, M, Mazzaro, C, Scaini, P, Lenzi, M, Campanini, M, Naclerio, C, A. T., Pietrogrande, M, Ferri, C, Mascia, M, Masolini, P, Zabotti, A, Maset, M, Roccatello, Dario, Zignego, A, Pioltelli, P, Gabrielli, A, Filippini, D, Perrella, O, Migliaresi, S, Galli, M, Bombardieri, S, and Monti, G.

Subjects
RHEUMATOID-FACTOR, GLOMERULONEPHRITIS, LONG-TERM, II MIXED CRYOGLOBULINEMIA, MANAGEMENT, HEPATITIS-C VIRUS, MONOCLONAL-ANTIBODY TREATMENT, EFFICACY, RIBAVIRIN, PEGYLATED INTERFERON-ALPHA-2B, HEPATITIS-C VIRUS, II MIXED CRYOGLOBULINEMIA, MONOCLONAL-ANTIBODY TREATMENT, LONG-TERM, PEGYLATED INTERFERON-ALPHA-2B, RHEUMATOID-FACTOR, EFFICACY, GLOMERULONEPHRITIS, MANAGEMENT, RIBAVIRIN
Published
2012

16. Epatite C: immunità e patologia

Author

SAGNELLI E, PERRELLA O, STANZIONE M, PERRELLA A., PASQUALE, Giuseppe, PERRELLA A, Sagnelli, E, Perrella, O, Stanzione, M, Pasquale, Giuseppe, and Perrella, A.

Published
2000

18. A randomized, controlled, multicenter phase iii study of the efficacy and safety of rituximab (rtx) monotherapy versus the best available treatment (bat) in patients with mixed cryoglobulinemia syndrome (MC) Ann Rheum Dis 2010;69(Suppl3):93

Author

DE VITA, Salvatore, Quartuccio, Luca, Masolini, P., Stefania, S., De Marchi, G., Zabotti, A., Mazzaro, C., Lenzi, P. Scaini M., Campanini, M., Scarpato, S., Tavoni, A., Pietrogrande, M., Ferri, C., Mascia, M. T., Roccatello, D., Zignego, A. L., Pioltelli, P., Gabrielli, A., Filippini, D., Perrella, O., Migliaresi, S., Galli, M., Monti, G., and Bombardieri, S.

Published
2010

20. OP0228 Rituximab Monotherapy of Severe Hcv-Related Cryoglobulinemic Vasculitis for More than 2 Years: Follow-Up of A Randomized Controlled Multicentre Study

Author

Quartuccio, L., primary, Zuliani, F., additional, Corazza, L., additional, Scaini, P., additional, Zani, R., additional, Lenzi, M., additional, Tavoni, A., additional, Sebastiani, M., additional, Baldovino, S., additional, Urraro, T., additional, Saccardo, F., additional, Sbreglia, C., additional, Mazzaro, C., additional, Pioltelli, P., additional, Fraticelli, P., additional, Filippini, D., additional, Gabrielli, A., additional, Perrella, O., additional, Scarpato, S., additional, Roccatello, D., additional, Zignego, A.L., additional, Ferri, C., additional, Bombardieri, S., additional, Pietrogrande, M., additional, Galli, M., additional, Monti, G., additional, and De Vita, S., additional

Published
2014
Full Text
View/download PDF

25. Immune signatures in human PBMCs of idiotypic vaccine for HCV-related lymphoproliferative disorders

Author

Buonaguro, L, Petrizzo, A, Tornesello, M, Napolitano, M, Martorelli, D, Castello, G, Beneduce, G, De Renzo, A, Perrella, O, Romagnoli, L, Sousa, V, De Re, V, Dolcetti, R, Buonaguro, FM, Buonaguro, L, Petrizzo, A, Tornesello, M, Napolitano, M, Martorelli, D, Castello, G, Beneduce, G, De Renzo, A, Perrella, O, Romagnoli, L, Sousa, V, De Re, V, Dolcetti, R, and Buonaguro, FM

Abstract

Hepatitis C virus (HCV) is one of the major risk factors for chronic hepatitis, which may progress to cirrhosis and hepatocellular carcinoma, as well as for type II mixed cryoglobulinemia (MC), which may further evolve into an overt B-cell non-Hodgkin's lymphoma (NHL). It has been previously shown that B-cell receptor (BCR) repertoire, expressed by clonal B-cells involved in type II MC as well as in HCV-associated NHL, is constrained to a limited number of variable heavy (VH)- and light (VL)-chain genes. Among these, the VK3-20 light chain idiotype has been selected as a possible target for passive as well as active immunization strategy. In the present study, we describe the results of a multiparametric analysis of the innate and early adaptive immune response after ex vivo stimulation of human immune cells with the VK3-20 protein. This objective has been pursued by implementing high-throughput technologies such as multiparameter flow cytometry and multiplex analysis of cytokines and chemokines.

Published
2010

26. Antifungal prophylaxis with liposomal amphotericin B and caspofungin in high-risk patients after liver transplantation: impact on fungal infections and immune system.

Author

Perrella, A., Esposito, C., Amato, G., Perrella, O., Migliaccio, C., Pisaniello, D., Calise, F., Cuomo, O., and Santaniello, W.

Abstract

Antifungal prophylaxis may be required in high-risk patients undergoing liver transplantation and for that reason we aimed to verify its role and its related impact on the graft. From January 2006 throughout 2012, 250 liver transplants were evaluated and 54 patients identified as being at higher risk were randomly selected to undergo the following schedule: 28 patients received liposomal amphotericin B and 26 received caspofungin. We evaluated, throughout 12 months, renal and liver function tests, bacterial and fungal infection episodes, and intensive care unit (ICU) stay, as well as the Th1 and Th2 cytokine network. Differences were analyzed according to non-parametric tests (two-tailedpvalues). Neither of the groups showed episodes of invasive fungal infection during the 12 months follow-up; however, patients receiving prophylaxis with liposomal amphotericin B had reduced episodes of bacterial infections coupled with an improved immune system response compared with those receiving caspofungin. Finally, a reduced stay in the ICU was also observed. In conclusion, even if the results of liposomal amphotericin B and caspofungin prophylaxis strategies did not differ in terms of invasive fungal infection rate, patients receiving prophylaxis with liposomal amphotericin B had a reduced ICU stay and an improved Th2 status, as well as a reduced number of post-transplant bacterial infections. Further studies are required to better address and evaluate these findings. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

28. Problematiche assistenziali di programmazione in un campione di persone con AIDS a Napoli = The health care problems of planning services in a sample of persons with AIDS in Naples

Author

Marazzi, M, Mancinelli, S, Palombi, L, Liotta, G, Chirianni, A, Liuzzi, G, Paone, G, Manzillo, E, Maio, G, Soscia, E, Perrella, O, Piazza, M, Soscia, M, and Pana', A

Subjects
Male, Questionnaires, Adult, Acquired Immunodeficiency Syndrome, Adolescent, Urban Population, Settore MED/42 - Igiene Generale e Applicata, Middle Aged, Female, Delivery of Health Care, Italy, Humans, HIV-1, Socioeconomic Factors, Activities of Daily Living, Health Planning
Published
1994

30. Rapid virological response in peripheral blood mononuclear cells with an increase of hepatitis C virus-specific interferon-gamma production predisposes to sustained virological response in patients with chronic hepatitis C genotype 1 undergoing treatment with pegylated-interferon alpha 2a plus ribavirin

Author

Perrella, A., primary, Sbreglia, C., additional, Atripaldi, L., additional, Esposito, C., additional, D'Antonio, A., additional, and Perrella, O., additional

Published
2009
Full Text
View/download PDF

32. Soluble interleukin-2 receptor and soluble CD8 molecules in cerebrospinal fluid and serum of patients with multiple sclerosis

Author

Carrieri, P. B., Soscia, E., Iacovitti, B., Pellicano, M., D Antonio, A., Vincenzo Provitera, Perrella, O., Carrieri, PIETRO BIAGIO, E., Soscia, B., Iacovitti, M., Pellicano, A., D'Antonio, V., Provitera, and O., Perrella

Subjects
Adult, Male, Multiple Sclerosis, Adult, Antigen, metabolism, Receptor, CD8 Antigens, T-Lymphocytes, analysis, T-Lymphocyte, Receptors, Interleukin-2, CD8, Middle Aged, Lymphocyte Activation, analysis, Biological Markers, Female, Humans, Lymphocyte Activation, Male, Middle Aged, Multiple Sclerosi, secretion, metabolism, Nervous System Disease, Interleukin-2, Humans, Female, Nervous System Diseases, Biomarkers
Abstract

The purpose of this study was to analyse soluble interleukin-2 receptor (sIL-2R) and soluble CD8 (sCD8) molecules in the cerebrospinal fluid (CSF) and serum of 18 patients with definite multiple sclerosis (MS) and of 16 with noninflammatory neurologic diseases (NIND). All MS patients suffered from an exacerbation of the relapsing-remitting form of the disease within one month before examination. The mean serum levels of sIL-2R and sCD8 in the MS patients were not significantly different from those of NIND patients. Only one patient with MS had detectable sIL-2R in the CSF. CSF sCD8 was detectable in 10 of 18 MS patients and in 1 of 16 NIND patients. Our data indicate that the CSF and serum sIL-2R concentrations do not correlate with the disease activity. Conversely, increased levels of sCD8 only in the CSF of MS patients support the hypothesis of an intrathecal activation of CD8+ cells in MS. We think that CSF sCD8 can be a useful marker for the presence of activated T cells in the central nervous system.

Published
1992

33. Interleucina-6 e granulócito-macrófago-CSF no líquido cefalorraquidiano de pacientes infectados por HIV com comprometimento do sistema nervoso central

Author

Perrella, O., Guerriero, M., Izzo, E., Soscia, M., and Carrieri, P. B.

Subjects
body regions, cytokines (interleukin-6, granulocyte-macrophage-CSF), líquido cefalorraquidiano, citocinas (interleucina-6, granulócito-macrófago-CSF), cerebrospinal fluid, AIDS-demência complexo, AIDS dementia complex
Abstract

We detected the cytokines interleukin-6 (IL-6) and granulocyte macrophage-CSF (GM-CSF) by ELISA in the CSF and serum of 30 HIV-infected patients classified as AIDS dementia complex (ADC), and 20 subjects with other neurological diseases (OND). We have found a high incidence of detectable IL-6 and GM-CSF in the CSF of ADC patients compared with OND patients. No statistical differences were observed between both groups for serum IL-6 and GM-CSF levels. These results suggest an intrathecal synthesis of these cytokines and a possible involvement in the pathogenesis of ADC. Detectamos as citocinas interleucina-6 (IL-6) e granulócito-macrófago-CSF (GM-CSF) por ELISA no LCR e soro de 30 pacientes infectados por HIV classificados como tendo AIDS-demência complexo (ADC) e de 20 pacientes com outras doenças neurológicas (OND). Encontramos elevada incidência de IL-6 e GM-CSF detectável no LCR de pacientes com ADC, em relação aos pacientes com OND. Diferenças estatísticas não foram observadas entre os dois grupos de pacientes para níveis de IL-6 e GM-CSF no soro. Esses resultados sugerem síntese intratecal dessas citocinas e sua possível participação na patogenia da ADC.

Published
1992

Catalog

Books, media, physical & digital resources
See catalog results