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2. Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health

3. Genetic links between ovarian ageing, cancer risk and de novo mutation rates

4. Genetic drivers and cellular selection of female mosaic X chromosome loss

5. Understanding the genetic complexity of puberty timing across the allele frequency spectrum

6. Saturation genome editing of BAP1 functionally classifies somatic and germline variants

9. Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

10. Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

12. Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease

14. Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum

15. Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk

16. Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation

20. Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

21. Rare variants in the MECP2 gene in girls with central precocious puberty: a translational cohort study

22. Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food

23. Author Correction: Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk

25. Genetic analyses identify widespread sex-differential participation bias

26. Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

27. Penetrance of Pathogenic Genetic Variants Associated With Premature Ovarian Insufficiency

28. Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity

29. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

30. Genetic association study of childhood aggression across raters, instruments, and age

32. Saturation genome editing of BAP1functionally classifies somatic and germline variants

33. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

34. Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss

35. Prevalence of Deleterious Variants in MC3R in Patients With Constitutional Delay of Growth and Puberty

36. Protein-truncating variants inBSNare associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease

37. Protein-truncating variants in BSNare associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease

38. Genetic basis of falling risk susceptibility in the UK Biobank Study

39. Prevalence of deleterious variants in MC3R in patients with constitutional delay of growth and puberty

40. GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

41. Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

42. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

43. Characterisation of dominant-negative GH receptor variants reveals a potential therapeutic target for short stature

44. Protein-truncating and rare missense variants in ATMand CHEK2and associations with cancer in UK Biobank whole-exome sequence data

45. Prevalence of Deleterious Variants in MC3Rin Patients With Constitutional Delay of Growth and Puberty

46. Associations of autozygosity with a broad range of human phenotypes

48. A Multiparametric Anti-Aging CRISPR Screen Uncovers a Role for BAF in Protein Translation

49. Monogenic causes of Premature Ovarian Insufficiency are rare and mostly recessive

50. A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein translation

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