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216 results on '"Persat F"'

1. Cerebral aspergillosis in the era of new antifungals: The CEREALS national cohort study Nationwide CEREbral Aspergillosis Lesional study (CEREALS)

Author

Serris, A., Benzakoun, J., Danion, F., Porcher, R., Sonneville, R., Wolff, M., Kremer, S., Letscher-Bru, V, Fekkar, A, Hekimian, G., Pourcher, V., Bougnoux, M-E., Poirée, S., Ader, F., Persat, F., Cotton, Francois, Tattevin, Pierre, Gangneux, J.-P., Lelièvre, L., Cassaing, S., Bonneville, Fabrice, Houze, S., Bretagne, Stephane, Herbrecht, R., Lortholary, O., Naggara, O., and Lanternier, F.

Published
2022
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2. P229 Do CFTR modulators interfere with microbiological diagnosis?

Author

Héry-Arnaud, G., primary, Vallet, S., additional, Bougnoux, M.-E., additional, Cardot-Martin, E., additional, Cassaing, S., additional, Chesnay, A., additional, Crémet, L., additional, Doléans-Jordheim, A., additional, Dupont, C., additional, Ferroni, A., additional, Gangneux, J.-P., additional, Garnier, F., additional, Guet-Revillet, H., additional, Guillard, T., additional, Handala, L., additional, Herrmann, J.-L., additional, Jeannot, K., additional, Lachaud, L., additional, Le Gal, S., additional, Lehours, P., additional, Mainardi, J.-L., additional, Millon, L., additional, Piau, C., additional, Persat, F., additional, Villena, I., additional, Yéra, H., additional, Velo-Suarez, L., additional, and Delhaes, L., additional

Published
2024
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3. Antifungal susceptibility testing practices in mycology laboratories in France, 2018

Author

Bellanger, A.-P., Persat, F., Foulet, F., Bonnal, C., Accoceberry, I., Angebault, C., Angoulvant, A., Augereau, O., Bailly, E., Bert, F., Bonhomme, J., Bouchara, J.-P., Bougnoux, M.-E., Bourdeau, P., Bouteille, B., Brun, S., Brunet, K., Camin-Ravenne, A.-M., Cassaing, S., Chouaki, T., Cornet, M., Costa, D., Desbois, N., Dorin, J., Fekkar, A., Fiacre, A., Fréalle, E., Gangneux, J.-P., Guillot, J., Guitard, J., Hasseine, L., Huguenin, A., Lachaud, L., Larréché, S., Lavergne, R.-A., Le Gal, S., Le Govic, Y., Letscher-Bru, V., Machouart, M., Mazars, E., Nourrisson, C., Paugam, A., Ranque, S., Risco-Castillo, V., Sasso, M., Sautour, M., Sendid, B., Senghor, Y., Botterel, F., and Dannaoui, Eric

Published
2020
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12. Dermatophytoses à Trichophyton mentagrophytesde génotype VII : une IST émergente de présentation clinique polymorphe

Author

Porquet, A., Wirbel, C., Godinot, M., Persat, F., Menotti, J., Danset, M., and Durupt, F.

Abstract

Trichophyton mentagrophytesa longtemps été considéré comme un dermatophyte zoophile. Cependant, plusieurs publications récentes ont décrit une transmission sexuelle interhumaine de T. mentagrophytes. En 2019, un nouveau génotype de T. mentagrophytes(génotype VII : TMVII) a été identifié à Berlin, responsable d’une épidémie de dermatophytoses pubiennes et génitales sexuellement transmises touchant les hommes et les femmes. En 2021–2022, une épidémie de TMVII a été signalée chez des hommes ayant des rapports sexuels avec des hommes (HSH) à Paris.

Published
2024
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25. Prospective evaluation of a new Aspergillus IgG EIA kit for the diagnosis of chronic and allergic pulmonary aspergillosis

Author

Dumollard , C., Bailly , S., Perriot , S., Brenier-Pinchart , M. P., Saint-Raymond , C., Camara , B., Gangneux , J. P., Persat , F., Valot , S., Grenouillet , F., Pelloux , H., Pinel , C., Cornet , M., Institut de Biologie et Pathologie, CHU Grenoble, Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC), Institut d'oncologie/développement Albert Bonniot de Grenoble (INSERM U823), Institut National de la Santé et de la Recherche Médicale (INSERM)-EFS-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF), Laboratoire Adaptation et pathogénie des micro-organismes [Grenoble] (LAPM), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Institut de biologie moléculaire des plantes (IBMP), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Institut de recherche en santé, environnement et travail (Irset), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de la Santé et de la Recherche Médicale (INSERM)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université d'Angers (UA), CHU Pontchaillou [Rennes], Hospices Civils de Lyon (HCL), Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), CHU Dijon, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), service de parasito-mycologie CHU Besancon, Service de parasitologie et mycologie [CHRU de Besançon], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Laboratoire Chrono-environnement (UMR 6249) (LCE), Infection, Antimicrobiens, Modélisation, Evolution ( IAME ), Université Paris Diderot - Paris 7 ( UPD7 ) -Université Paris 13 ( UP13 ) -Université Sorbonne Paris Cité ( USPC ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Institut d'oncologie/développement Albert Bonniot de Grenoble ( INSERM U823 ), Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble-EFS-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Laboratoire Adaptation et pathogénie des micro-organismes [Grenoble] ( LAPM ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Centre National de la Recherche Scientifique ( CNRS ), Université Joseph Fourier - Grenoble 1 ( UJF ) -CHU Grenoble, Institut de biologie moléculaire des plantes ( IBMP ), Université de Strasbourg ( UNISTRA ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de recherche, santé, environnement et travail ( Irset ), Université d'Angers ( UA ) -Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -École des Hautes Études en Santé Publique [EHESP] ( EHESP ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) -Université des Antilles ( UA ), Hospices Civils de Lyon ( HCL ), Laboratoire de Biométrie et Biologie Evolutive ( LBBE ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique ( Inria ) -Centre National de la Recherche Scientifique ( CNRS ), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon ), service de parasitologie mycologie CHU Jean Minjoz BESANCON, Hôpital Jean Minjoz-Hôpital Jean Minjoz, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications [Grenoble] ( TIMC-IMAG ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut polytechnique de Grenoble - Grenoble Institute of Technology ( Grenoble INP ) -IMAG-Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Brenner, Nelly

Subjects
Chronic pulmonary aspergillosis, allergic bronchopulmonary aspe rgillosis, IgG antibodies, precipitins, [SDV.MP.MYC] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, enzyme immunoassay, [ SDV.MP.MYC ] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, ComputingMilieux_MISCELLANEOUS, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology
Abstract

International audience; Anti-Aspergillus IgG antibodies are important biomarkers for the diagnosis of chronic pulmonary aspergillosis (CPA) and allergic bronchopulmonary aspergillosis (ABPA). We compared the performance of a new commercial EIA (Bordier Affinity Products) with those of the Bio-Rad and Virion\Serion EIAs. This assay is novel in the association of two recombinant antigens with somatic and metabolic antigens of A. fumigatus. In a prospective multicentre study, 436 serum samples from 147 patients diagnosed with CPA (136 sera/104 patients) or ABPA (94 sera/43 patients) and from 205 controls (206 sera) were tested. We obtained sensitivities of 97%, 91.7%, and 86.1%, and specificities of 90.3%, 91.3%, and 81.5% for the Bordier, Bio-Rad and Virion\Serion tests, respectively. The Bordier kit was more sensitive than the Bio-Rad kit (p < 0.01), which was itself more sensitive than the Virion\Serion kit (p=0.04). The Bordier and Bio-Rad kits had similar specificities (p=0.8), both higher than that of the Virion\Serion kit (p=0.02). The areas under the ROC curves confirmed the superiority of the Bordier kit over the Bio-Rad and the Virion\Serion kits (0.977, 0.951 and 0.897, respectively; p < 0.01 for each comparison). In a subset analysis of 279 sera tested with the Bordier and Bio-Rad kits and an in-house immunoprecipitin assay (IPD), the Bordier kit had the highest sensitivity (97.7%), but the IPD tended to be more specific (71.2 and 84.7%, respectively; p=0.10).The use of recombinant, somatic and metabolic antigens in a single EIA improved the balance between sensitivity and specificity, resulting in an assay highly suitable for use in the diagnosis of chronic and allergic aspergillosis.

Published
2016
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27. Acute graft-versus-host disease, invasive aspergillosis and Clostridium difficile colitis after peripheral blood stem cell transplantation: a complex network of causalities and a challenge for prevention

Author

Khanafer, N., Antoine Neuraz, Bénet, T., Cour, M., Persat, F., Labussière, H., Argaud, L., Michallet, M., Philippe Vanhems, Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV]Life Sciences [q-bio]
Published
2015

30. Évaluation prospective d’un nouveau kit ELISA pour la détection des IgG anti- Aspergillus dans le diagnostic des aspergilloses pulmonaires chroniques et allergiques

Author

Dumollard, C., primary, Bailly, S., additional, Perriot, S., additional, Brenier-Pinchart, M., additional, Saint-Raymond, C., additional, Camara, B., additional, Gangneux, J., additional, Persat, F., additional, Valot, S., additional, Grenouillet, F., additional, Pelloux, H., additional, Pinel, C., additional, and Cornet, M., additional

Published
2016
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31. Antigènes aspergillaires chez les patients sous chimiothérapie pour leucémie myéloïde aiguë ou allogreffe de cellules souches hématopoïétiques : rôle dans la prédiction d’aspergillose invasive et dans la modification de la stratégie thérapeutique

Author

Dupont, D., primary, Tran, V., additional, Gardes, S., additional, Monfray, J., additional, Ducastelle-Lepretre, S., additional, Sobh, M., additional, Nicolini, F., additional, Ecochard, R., additional, Michallet, M., additional, and Persat, F., additional

Published
2016
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32. Prospective Evaluation of a New Aspergillus IgG Enzyme Immunoassay Kit for Diagnosis of Chronic and Allergic Pulmonary Aspergillosis

Author

Dumollard, C., primary, Bailly, S., additional, Perriot, S., additional, Brenier-Pinchart, M. P., additional, Saint-Raymond, C., additional, Camara, B., additional, Gangneux, J. P., additional, Persat, F., additional, Valot, S., additional, Grenouillet, F., additional, Pelloux, H., additional, Pinel, C., additional, and Cornet, M., additional

Published
2016
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36. Chronic necrotizing aspergillosis

Author

Cristea, D, Cottin, Vincent, Persat, F, Meyronet, D, Cordier, Jf, Inconnu, Rétrovirus et Pathologie Comparée (RPC), Institut National de la Recherche Agronomique (INRA)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Ecole Nationale Vétérinaire de Lyon (ENVL), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2008

37. Aspergillus antibody detection: diagnostic strategy and technical considerations from the Société eFrançaise de Mycologie Médicale (French Society for Medical Mycology) expert committee.

Author

Persat, F., Hennequin, C., and Gangneux, J. P.

Abstract

Until now, there has been no consensus on the best method for the detection of anti-Aspergillus antibodies, a key diagnostic tool for chronic aspergilloses. To better appreciate the usage of and confidence in these techniques, the Société Française de Mycologie Médicale (French Society for Medical Mycology; SFMM) performed a two-step survey of French experts. First, we administered an initial survey to French labs performing Aspergillus serology to depict usage of the different techniques available for Aspergillus serology. Second, an opinion poll was conducted of 40 experts via an online questionnaire. Each item was rated from 1 to 9 according to the level of agreement. The initial survey revealed that enzyme-linked immunosorbent assay (ELISA) (81%) and immunoelectrophoresis (IEP) (67%) were the most commonly used techniques for screening and confirmation, respectively. The distinction between screening and confirmation techniques was confirmed by the experts (median = 7) with a 44.2% variation coefficient. Only ELISA for screening and IEP and Western blot (WB) for confirmation were clearly considered valuable methods (median ≥8 with variation coefficients less than 30%). The use of a confirmation technique was recommended in the case of a positive result in a compatible clinical context (cystic fibrosis, for example) or during the patient's follow-up. In the case of discordant results between the screening and confirmation techniques, the experts recommended greater confidence in the results obtained with the confirmation technique. All experts emphasized the need to standardize Aspergillus serology techniques and to better define the place of each of them in the diagnosis of aspergillosis. [ABSTRACT FROM AUTHOR]

Published
2017
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38. Characterization of an excreted/secreted antigen form of 14-3-3 protein in Toxoplasma gondii tachyzoites

Author

Assossou, O., Besson, Frédéric, Rouault, J.P., Persat, F., Ferrandiz, J., Mayencon, M., Peyron, François, Picot, Stéphane, Communications Cellulaires et Différenciation (CCD), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV]Life Sciences [q-bio], [INFO]Computer Science [cs]
Published
2004

40. Hepatic disorders during the simultaneous therapy with intraconazole and amphotericin B in leukemic patients

Author

Schwartzbrod, P.E., Persat, F., Troncy, J., Timour, Q., Maul, A., Piens, M.A., Fiere, D., Picot, S., Laboratoire Méthodes Mathématiques pour l'Analyse des Systèmes (MMAS), Centre National de la Recherche Scientifique (CNRS)-Université Paul Verlaine - Metz (UPVM), and Université Paul Verlaine - Metz (UPVM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV]Life Sciences [q-bio], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
1999

41. Evaluation de la tolérance clinique et biologique de l’intraconazole chez des patients présentant des taux sériques élevés

Author

Schwartzbrod, P.E., Persat, F., Troncy, J., Timour, Q., Maul, A., Piens, M.A., Fiere, D., Picot, S., Laboratoire Méthodes Mathématiques pour l'Analyse des Systèmes (MMAS), Université Paul Verlaine - Metz (UPVM)-Centre National de la Recherche Scientifique (CNRS), and MAUL, Armand

Subjects
[SDV] Life Sciences [q-bio], [STAT]Statistics [stat], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS, [STAT] Statistics [stat]
Abstract

International audience

Published
1998

44. Invasive aspergillosis: an important risk factor on the short- and long-term survival of acute myeloid leukemia (AML) patients

Author

Michallet, M., primary, Bénet, T., additional, Sobh, M., additional, Kraghel, S., additional, Hamri, M., additional, Cannas, G., additional, Nicolini, F. E., additional, Labussière, H., additional, Ducastelle, S., additional, Barraco, F., additional, Thomas, X., additional, Chelghoum, Y., additional, Nicolle, M.-C., additional, Bienvenu, A.-L., additional, Persat, F., additional, Monbrison, F., additional, Picot, S., additional, and Vanhems, P., additional

Published
2011
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49. Prospective Evaluation of a New AspergillusIgG Enzyme Immunoassay Kit for Diagnosis of Chronic and Allergic Pulmonary Aspergillosis

Author

Dumollard, C., Bailly, S., Perriot, S., Brenier-Pinchart, M. P., Saint-Raymond, C., Camara, B., Gangneux, J. P., Persat, F., Valot, S., Grenouillet, F., Pelloux, H., Pinel, C., and Cornet, M.

Abstract

ABSTRACTAnti-AspergillusIgG antibodies are important biomarkers for the diagnosis of chronic pulmonary aspergillosis (CPA) and allergic bronchopulmonary aspergillosis (ABPA). We compared the performance of a new commercial enzyme immunoassay (EIA) (Bordier Affinity Products) with that of the Bio-Rad and Virion\Serion EIAs. This assay is novel in its association of two recombinant antigens with somatic and metabolic antigens of Aspergillus fumigatus. In a prospective multicenter study, 436 serum samples from 147 patients diagnosed with CPA (136 samples/104 patients) or ABPA (94 samples/43 patients) and from 205 controls (206 samples) were tested. We obtained sensitivities of 97%, 91.7%, and 86.1%, and specificities of 90.3%, 91.3%, and 81.5% for the Bordier, Bio-Rad, and Virion\Serion tests, respectively. The Bordier kit was more sensitive than the Bio-Rad kit (P< 0.01), which was itself more sensitive than the Virion\Serion kit (P= 0.04). The Bordier and Bio-Rad kits had similar specificity (P= 0.8), both higher than that of the Virion\Serion kit (P= 0.02). The area under the receiver operating characteristic (ROC) curves confirmed the superiority of the Bordier kit over the Bio-Rad and the Virion\Serion kits (0.977, 0.951, and 0.897, respectively; P< 0.01 for each comparison). In a subset analysis of 279 serum samples tested with the Bordier and Bio-Rad kits and an in-house immunoprecipitin assay (IPD), the Bordier kit had the highest sensitivity (97.7%), but the IPD tended to be more specific (71.2 and 84.7%, respectively; P= 0.10). The use of recombinant, somatic, and metabolic antigens in a single EIA improved the balance of sensitivity and specificity, resulting in an assay highly suitable for use in the diagnosis of chronic and allergic aspergillosis.

Published
2016
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