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This essay surveys the use of the metaphors of illness, specifically those of constipation and diarrhea, in vernacular French Evangelical and Calvinist polemical theater of the 1520s and 30s (Berquin, Malingre, Marguerite d' Angoulême) through the 1560s (Badius). It considers the relatively frequent reference to staging of diagnosis, treatment, and cure in the context of contemporary medical belief and practice, and observes a shift in emphasis from optimistic prognosis and successful therapy of the earlier Evangelical period to negative pronouncement of imminent (and deserved) death in the later calvinist or Huguenot period at the start of the Wars of Religion.