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Your search keyword '"Pervova IuV"' showing total 5 results
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5 results on '"Pervova IuV"'

1. [The role of small molecules in regulation of activity of cytoplasmatic dehydrogenases].

Author

Gil'miiarova FN, Radomskaia VM, Miakisheva IuV, Baisheva GM, Pervova IuV, and Spiridonova NV

Subjects
Animals, Antioxidants metabolism, Antioxidants pharmacology, Central Nervous System Depressants metabolism, Central Nervous System Depressants pharmacology, Enzyme Activation drug effects, Erythrocytes enzymology, Ethanol pharmacology, Hydrogen Peroxide pharmacology, Oxidants metabolism, Oxidants pharmacology, Rabbits, Silymarin pharmacology, Cytoplasm enzymology, Ethanol metabolism, Hydrogen Peroxide metabolism, Oxidoreductases metabolism, Silymarin metabolism
Abstract

The influence of silistrong on the activity of erythrocyte cytoplasmatic dehydrogenases and also purified glyceraldehyde-3-phosphate dehydrogenase (GAPH) was studied. Silistrong and its biologically active components (ethanol and silimarine) were found to activate GAPDH, lactate dehydrogenase (LDH), alpha-glycerophosphate dehydrogenase (GPDH) both in lysates of erythrocytes and in isolated GAPDH. The compounds studied are able to protect these enzymes and also to restore their activity of enzymes modified by hydrogen peroxide. Maximal activity is a characteristic of silistrong.

Published
2006

2. [The influence of nutrition and environment on the nonspecific resistance of the organism and physical development of children].

Author

Gapparov MM and Pervova IuV

Subjects
Alcohol Drinking, Body Height, Body Weight, Case-Control Studies, Catalase blood, Child, Ecology, Environmental Exposure, Erythrocyte Membrane ultrastructure, Female, Hemoglobins analysis, Humans, Leukopenia pathology, Lymphopenia pathology, Male, Parents, Pregnancy, Pregnancy Complications epidemiology, Reference Values, Superoxide Dismutase blood, Urban Health, Adaptation, Physiological, Child Development, Child Nutritional Physiological Phenomena, Environment
Abstract

Decrease of adaptable opportunities at children from ecologically unsuccessful region with a defective diet is marked. Attributes deceleration, tendencies to leucopenia, lumphopenia, monocytopenia, reduction of the maintenance of hemoglobin are revealed. Change of structurally functional parameters of erithrocyto's membranes, infringement of a parity about and antioxidant processes is typical. Decrease of quality of health causes necessity of realization of improving actions.

Published
2005

3. [Levels of unified metabolites and thyroid hormones in blood and oral fluid of children with minimal brain dysfunction].

Author

Gil'miiarova FN, Pervova IuV, Radomskaia VM, Gergel' NI, and Tarasova SV

Subjects
Attention Deficit Disorder with Hyperactivity blood, Carboxylic Acids analysis, Carboxylic Acids blood, Child, Child, Preschool, Female, Glucose analysis, Humans, Lipids analysis, Lipids blood, Oxidation-Reduction, Pregnancy, Pregnancy Complications, Proteins analysis, Thyroid Hormones blood, Attention Deficit Disorder with Hyperactivity metabolism, Saliva chemistry, Saliva metabolism, Thyroid Hormones analysis
Abstract

Minimal brain dysfunctions in children with various perinatal complications are accompanied by metabolic imbalance manifested by decreased total protein content, the tendency to reduced triglycerides, increased cholesterol concentrations in the oral fluid, the trend to hypoproteinaemia, hypoglycaemia, hypotriglyceridaemia. The most significant changes in the redox systems alpha-ketoglutarate-glutamate, oxaloacetate-malate, pyruvate-lactate, dioxyacetone phosphate-alpha-glycerophosphate in biological fluids were revealed in cases of antenatal alcoholisation. A certain correlation was found between anemia in pregnant women and hypothyroidal background in children. In addition, a high level of free and total thyroxine, that of total triiodthyronine were found in the oral fluid. Hypophysis--thyroid dysregulation in children with minimal brain dysfunction associated with gestosis in their mothers during pregnancy, was manifested by decreased content of total and free T4 and T3 in blood serum and increased level of the thyroid-stimulating hormone.

Published
2004

4. [On the mechanisms of the alcohol action on human organism].

Author

Pervova IuV

Subjects
Alcoholic Intoxication etiology, Ethanol chemistry, Ethanol toxicity, Humans, Ethanol metabolism, Ethanol pharmacology
Abstract

In article is discussed the information on properties of alcohol, distribution in organism, systems of oxidation, elimination, biological activity of ethanol and acetaldehyde, mechanisms of damaging action of an alcoholic intoxication.

Published
2004

5. [The role of hyperlactatedehydrogenasemia in induction of metabolic disorders in the body].

Author

Gil'miiarova FN, Radomskaia VM, Baisheva GM, Kretova IG, Kleĭman MS, and Pervova IuV

Subjects
Animals, Brain enzymology, Brain metabolism, Glycolysis, Kidney enzymology, Kidney metabolism, L-Lactate Dehydrogenase blood, L-Lactate Dehydrogenase pharmacology, Liver enzymology, Liver metabolism, Mitochondria enzymology, Mitochondria metabolism, Muscle, Skeletal enzymology, Muscle, Skeletal metabolism, Myocardium enzymology, Myocardium metabolism, Organ Specificity, Oxidation-Reduction, Rabbits, Spleen enzymology, Spleen metabolism, Tritium, L-Lactate Dehydrogenase metabolism
Abstract

The effect of intravenous administration of lactate dehydrogenase (5000 E/kg) on some metabolic parameters was investigated. The hyperenzymemia was accompanied by changes of metabolite content (glutamate, 2-oxoglutarate, lactate, dihydroxyacetone phosphate) and enzyme activities (aldolase, lactate dehydrogenase, transaminase) in heart, liver and skeletal muscles. Intravenously administered tritiated lactate dehydrogenase was preferentially found in skeletal muscles, liver, kidneys and some other organs.

Published
2001

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