250 results on '"Pesce, Emanuela"'
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2. Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators.
3. Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine.
4. In silico drug repositioning on F508del-CFTR: A proof-of-concept study on the AIFA library
5. Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays
6. Beyond Kaftrio : mechanistic insights to maximize N1303K-CFTR rescue
7. Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del‐CFTR
8. Therapeutic approaches to CFTR dysfunction: From discovery to drug development
9. High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel
10. Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools
11. Molybdenum disilicide-silicon nitride bushing nozzles tailor-made for basalt fibers production
12. Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel
13. Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators
14. Synthesis and structure–activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis
15. Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background
16. Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing
17. Changing the Microstructural and Chemical Properties of Graphene Oxide Through a Chemical Route
18. Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5.
19. The Value and Relevance of the T Cell Lymphoma Registries and International Collaborations: the Case of COMPLETE and the T-Cell Project
20. Surface Analytical Characterization of P3HT-Streptavidin Bilayers for Biosensing Applications
21. Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect
22. The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs
23. Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays
24. Supplemental Material - Changing the Microstructural and Chemical Properties of Graphene Oxide Through a Chemical Route
25. Morphology and microstructure of core-shell GaAs/GaxAl1-xAs nanowires investigated by He-ion microscopy and X-ray reciprocal space mapping
26. Probing Allosteric Hsp70 Inhibitors by Molecular Modelling Studies to Expedite the Development of Novel Combined F508del CFTR Modulators
27. Venetoclax Shows Low Therapeutic Activity in BCL2-Positive Relapsed/Refractory Peripheral T-Cell Lymphoma: A Phase 2 Study of the Fondazione Italiana Linfomi
28. Is ZAP70 still a key prognostic factor in early stage chronic lymphocytic leukaemia? Results of the analysis from a prospective multicentre observational study
29. Evaluation of the degree of dispersion of nanofillers by mechanical, rheological, and permeability analysis
30. Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis
31. The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel
32. Prospective validation of a risk score based on biological markers for predicting progression free survival in Binet stage A chronic lymphocytic leukemia patients: Results of the multicenter O-CLL1-GISL study
33. Synthesis and Structure-activity Relationship of Aminoarylthiazole Derivatives as Potential Potentiators of the Chloride Transport Defect in Cystic Fibrosis
34. Total body computed tomography scan in the initial work-up of Binet stage A chronic lymphocytic leukemia patients: Results of the prospective, multicenter O-CLL1-GISL study
35. Chromosome 2p gain in monoclonal B-cell lymphocytosis and in early stage chronic lymphocytic leukemia
36. A high‐content drug screening strategy to identify protein level modulators for genetic diseases: A proof‐of‐principle in autosomal dominant leukodystrophy
37. Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators
38. Distinctive lipid signatures of bronchial epithelial cells associated with cystic fibrosis drugs, including Trikafta
39. GM1 as Adjuvant of Innovative Therapies for Cystic Fibrosis Disease
40. Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel
41. Strain sensitivity in ion-implanted polymers
42. Incidence and outcomes of rare T cell lymphomas from the T Cell Project: hepatosplenic, enteropathy associated and peripheral gamma delta T cell lymphomas
43. High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation
44. Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia
45. A high‐content drug screening strategy to identify protein level modulators for genetic diseases: A proof‐of‐principle in autosomal dominant leukodystrophy.
46. Incidence and outcomes of rare T cell lymphomas from the T Cell Project: hepatosplenic, enteropathy associated and peripheral gamma delta T cell lymphomas.
47. The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism
48. Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia
49. Rituximab plus bendamustine as front-line treatment in frail elderly (>70 years) patients with diffuse large B-cell non-Hodgkin lymphoma: a phase II multicenter study of the Fondazione Italiana Linfomi
50. The outcome of peripheral T-cell lymphoma patients failing first-line therapy: a report from the prospective, International T-Cell Project
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