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This paper explores a mathematical model of malaria, focusing on the basic reproduction number (R0) and employing Lyapunov functions to assess the global stability of disease-free and endemic equilibria. Sensitivity analysis of key parameters is conducted to evaluate their impact on disease control. The results indicate an active malaria outbreak with decreasing human classes signifying disease progression and increasing mosquito classes suggesting heightened transmission risk. Effective control measures, including mosquito control and treatment of infected individuals, are essential to mitigate the outbreak. [ABSTRACT FROM AUTHOR]

We propose a mathematical model of the coronavirus disease 2019 (COVID-19) to investigate the transmission and control mechanism of the disease in the community of Nigeria. Using stability theory of differential equations, the qualitative behavior of model is studied. The pandemic indicator represented by basic reproductive number R0 is obtained from the largest eigenvalue of the next-generation matrix. Local as well as global asymptotic stability conditions for the disease-free and pandemic equilibrium are obtained which determines the conditions to stabilize the exponential spread of the disease. Further, we examined this model by using Atangana-Baleanu fractional derivative operator and existence criteria of solution for the operator is established. We consider the data of reported infection cases from April 1, 2020, till April 30, 2020, and parameterized the model. We have used one of the reliable and efficient method known as iterative Laplace transform to obtain numerical simulations. The impacts of various biological parameters on transmission dynamics of COVID-19 is examined. These results are based on different values of the fractional parameter and serve as a control parameter to identify the significant strategies for the control of the disease. In the end, the obtained results are demonstrated graphically to justify our theoretical findings. [ABSTRACT FROM AUTHOR]