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Objective: Cancers are currently adjudged as a hindrance to achieving a desirable life expectancy in most countries. The high mortality rate from ovarian cancer is a result of the pathology not having specific symptoms, late presentation, and lack of proper screening that results in its diagnosis in the advanced stages. The study aimed to determine the prevalence, clinical presentation, and outcome after the management of patients with ovarian cancer seen in the tertiary institution. Methodology: It was a retrospective study. Relevant information was extracted from the case files of the patients with histologically confirmed ovarian cancer. The data obtained were analysed using Statistical Package for Social Sciences (SPSS) statistical software, version 23. Results: Thirty-two cases of ovarian cancer were admitted during the period under review. This constituted 21.0% of gynaecological malignancies managed in the hospital during the study. The mean age of the ovarian cancer patients was 50.94±12.01 years with 56.25% of the patients being postmenopausal. The majority of the patients (62.4%) have 3 or more parous experiences with 53.1% of the patients presenting with advanced disease. Epithelial ovarian cancer was the most common histological variant. The treatment modality was surgery and chemotherapy. However, 65.7% of patients defaulted from initiating or completing chemotherapy. Conclusion: The study revealed that patients presented in the late stage of the disease and a bulk of them did not complete the treatment. There is a need to lobby Governments to subsidize cancer treatment, especially in the area of chemotherapy treatment.

Background: Cervical cancer is still a public health problem in many developing countries, like Nigeria. HIV infection makes HPV infections last longer, progress to squamous intraepithelial lesion of the cervix, and eventually lead to invasive cervical cancer. Objective: Find out how often squamous intraepithelial lesions (SIL) happen and what causes them in HIV-positive women in Sagamu, southwest Nigeria. Methods. A cross-sectional study was done with 165 women with HIV and 165 women without HIV. Pap smears were done on all of the people in the study. The data was looked at with IBM-SPSS Windows v. 23. Results: Both groups were about the same age and had the same number of children (P=0.194 and P=0.388, respectively). The participants’ average age (SD) was 36.8 (5.6), and the median number of children they had was 3. HIV-positive women were much more likely to have an abnormal cytology smear (24.8%) than HIV-negative women (7.3%) (2 = 18.904, P 0.001). There wasn’t a link between having HIV and the severity of cervical lesions (2 = 3.66, P = 0.162). A CD4 cell count of less than 350 cells/mm3was found to be a strong predictor of an abnormal cervical cytological smear in HIV-positive women (AOR: 25.5; CI: 8.8-73.5; P 0.001). Conclusion: In Sagamu, Nigeria, the number of HIV-positive women with SIL of the cervix was much higher than the number of HIVnegative women with SIL of the cervix. HIV-positive women, especially those with a low number of CD4 cells, need cervical smear tests more often. This will make sure that pre-invasive lesions are found and treated as soon as possible.