1. Effect of a plasma sodium biofeedback system applied to HFR on the intradialytic cardiovascular stability. Results from a randomized controlled study
- Author
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Francesco Locatelli, Luigi Coli, Filippo Aucella, Peter Ahrenholz, Francesco Quarello, Paola Mesiano, Sibilla Sagripanti, Joan Fort, Thierry Petitclerc, Carmine Stallone, Roland E. Winkler, Antonio Gesuete, Lise Mandart, Sergio Stefoni, Andrea Serra, Carlo Navino, Simeone Andrulli, Antonio Scarlatella, Giovanni M. Frascà, Christian Tielemans, Christine Fumeron, Silvana Savoldi, Salvatore Di Filippo, Locatelli F, Stefoni S, Petitclerc T, Colì L, Di Filippo S, Andrulli S, Fumeron C, Frascà GM, Sagripanti S, Savoldi S, Serra A, Stallone C, Aucella F, Gesuete A, Scarlatella A, Quarello F, Mesiano P, Ahrenholz P, Winkler R, Mandart L, Fort J, Tielemans C, Navino C., and Internal Medicine Specializations more...
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Male ,biofeedback ,sodium online measure ,medicine.medical_specialty ,Time Factors ,SODIUM ONLINE ,medicine.medical_treatment ,Blood Pressure ,Hemodiafiltration ,law.invention ,Randomized controlled trial ,INTRADIALYTIC HYPOTENSION ,law ,Hfr cell ,Hemofiltration ,medicine ,Clinical endpoint ,Humans ,Prospective Studies ,Plasma Volume ,Prospective cohort study ,Dialysis ,Aged ,Aged, 80 and over ,Transplantation ,Cross-Over Studies ,Néphrologie - urologie ,business.industry ,Sodium ,Hemodynamics ,intradialytic hypotension ,Biofeedback, Psychology ,Middle Aged ,biochemical phenomena, metabolism, and nutrition ,equipment and supplies ,Transplantation d'organes ,Crossover study ,Surgery ,carbohydrates (lipids) ,Blood pressure ,BIOFEEDBACK ,Nephrology ,Anesthesia ,Kidney Failure, Chronic ,bacteria ,Female ,Hypotension ,business - Abstract
BackgroundIntradialytic hypotension (IDH) is still a major clinical problem for haemodialysis (HD) patients. Haemodiafiltration (HDF) has been shown to be able to reduce the incidence of IDH.MethodsFifty patients were enrolled in a prospective, randomized, crossover international study focussed on a variant of traditional HDF, haemofiltration with endogenous reinfusion (HFR). After a 1-month run-in period on HFR, the patients were randomized to two treatments of 2 months duration: HFR (Period A) or HFR-Aequilibrium (Period B), followed by a 1-month HFR wash-out period and then switched to the other treatment. HFR-Aequilibrium (HFR-Aeq) is an evolution of the haemofiltration with endogenous reinfusion (HFR) dialysis therapy, with dialysate sodium concentration and ultrafiltration rate profiles elaborated by an automated procedure. The primary end point was the frequency of IDH.ResultsSymptomatic hypotension episodes were significantly lower on HFR-Aeq versus HFR (23 ± 3 versus 31 ± 4 of sessions, respectively, P l l0.03), as was the per cent of clinical interventions (17 ± 3 of sessions with almost one intervention on HFR-Aeq versus 22 ± 2 on HFR, P, SCOPUS: ar.j, info:eu-repo/semantics/published more...
- Published
- 2012
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