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1. High Accuracy Prediction of PROTAC Complex Structures

3. Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity

4. Unraveling the Photoactivation Mechanism of a Light-Activated Adenylyl Cyclase Using Ultrafast Spectroscopy Coupled with Unnatural Amino Acid Mutagenesis

7. Impact of Target Turnover on the Translation of Drug-Target Residence Time to Time-Dependent Antibacterial Activity

9. The biodistribution of 5-[18F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomography.

12. Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA

13. Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix

14. Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[18F]F-p-Aminobenzoic Acid

15. Correlating Drug–Target Residence Time and Post-antibiotic Effect: Insight into Target Vulnerability

16. Functional dynamics of a single tryptophan residue in a BLUF protein revealed by fluorescence spectroscopy

18. Excited State Resonance Raman of flavin mononucleotide: Comparison of theory and experiment

19. Site-Specific Protein Dynamics Probed by Ultrafast Infrared Spectroscopy of a Noncanonical Amino Acid

20. Pharmacokinetic–pharmacodynamic models that incorporate drug–target binding kinetics

21. A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure

22. Identification of the vibrational marker of tyrosine cation radical using ultrafast transient infrared spectroscopy of flavoprotein systems

23. Exploring the chemical space of 1,2,3-triazolyl triclosan analogs for discovery of new antileishmanial chemotherapeutic agents

26. Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in

27. Excited State Vibrations of Isotopically Labeled FMN Free and Bound to a Light-Oxygen-Voltage (LOV) Protein

28. Positron Emission Tomography Imaging of

29. Ultrafast Protein Dynamics Probed by Site Specific Transient IR Spectroscopy

30. Positron Emission Tomography Imaging with 2-[18F]F-p-Aminobenzoic Acid Detects Staphylococcus aureus Infections and Monitors Drug Response

31. Structure–kinetic relationships that control the residence time of drug–target complexes: insights from molecular structure and dynamics

32. Drug–Target Kinetics in Drug Discovery

33. Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors

34. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy

35. Stereoselective Synthesis, Docking, and Biological Evaluation of Difluoroindanediol-Based MenE Inhibitors as Antibiotics

36. Erratum for DeMarco et al., 'Determination of [ 11 C]Rifampin Pharmacokinetics within Mycobacterium tuberculosis-Infected Mice by Using Dynamic Positron Emission Tomography Bioimaging'

37. Vibrational spectroscopy of flavoproteins

38. Antibacterial Activity and Mode of Action of a Sulfonamide-Based Class of Oxaborole Leucyl-tRNA Synthetase Inhibitors

39. Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE

40. Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis

41. Vibrational spectroscopy of flavoproteins

42. Featured Article Editorial

43. Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase

44. A Methyl 4-Oxo-4-phenylbut-2-enoate with in Vivo Activity against MRSA That Inhibits MenB in the Bacterial Menaquinone Biosynthesis Pathway

45. Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase

47. Positron Emission Tomography Imaging with 2-[

48. Editorial overview: Next generation therapeutics

49. Infrared spectroscopy reveals multi-step multi-timescale photoactivation in the photoconvertible protein archetype dronpa

50. Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA

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