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6. Comparison of Patient Health Questionnaire-9, Edinburgh Postnatal Depression Scale and Hospital Anxiety and Depression – Depression subscale scores by administration mode: An individual participant data differential item functioning meta-analysis

Author

Azar, Marleine, Bhandari, Parash Mani, Chiovitti, Matthew J., He, Chen, Imran, Mahrukh, Krishnan, Ankur, Negeri, Zelalem, Neupane, Dipika, Riehm, Kira E., Yan, Xin Wei, Kloda, Lorie A., Henry, Melissa, Ismail, Zahinoor, Loiselle, Carmen G., Mitchell, Nicholas D., Al-Adawi, Samir, Alvarado, Rubén, Amtmann, Dagmar, Arroll, Bruce, Ayalon, Liat, Baradaran, Hamid R., Barnes, Jacqueline, Beck, Kevin R., Beck, Cheryl Tatano, Bernstein, Charles N., Bindt, Carola, Bombardier, Charles H., Boye, Birgitte, Büel-Drabe, Natalie, Buji, Ryna Imma, Bunevicius, Adomas, Butterworth, Peter, Can, Ceyhun, Carter, Gregory, Chagas, Marcos H., Chan, Juliana C.N., Chan, Lai Fong, Chen, Chih-Ken, Chibanda, Dixon, Chorwe-Sungani, Genesis, Clover, Kerrie, Conroy, Ronán M., Conway, Aaron, Conwell, Yeates, Correa, Humberto, Couto, Thiago Castro e, Cukor, Daniel, Daray, Federico M., de Man-van Ginkel, Janneke M., De Souza, Jennifer, Downing, Marina G., Eapen, Valsamma, Fann, Jesse R., Favez, Nicolas, Felice, Ethel, Fellmeth, Gracia, Ferentinos, Panagiotis P., Fernandes, Michelle, Field, Sally, Figueiredo, Barbara, Fischer, Felix H., Fisher, Jane R.W., Flint, Alastair J., Fujimori, Maiko, Fung, Daniel S.S., Gallagher, Pamela, Gandy, Milena, Gelaye, Bizu, Gholizadeh, Leila, Gibson, Lorna J., Goodyear-Smith, Felicity, Grassi, Luigi, Green, Eric P., Greeno, Catherine G., Hall, Brian J., Hantsoo, Liisa, Haroz, Emily E., Härter, Martin, Hegerl, Ulrich, Helle, Nadine, Hernando, Asuncion, Hides, Leanne, Hobfoll, Stevan E., Honikman, Simone, Howard, Louise M., Hyphantis, Thomas, Iglesias-González, Maria, Inagaki, Masatoshi, Jenewein, Josef, Jeon, Hong Jin, Jetté, Nathalie, Julião, Miguel, Kettunen, Pirjo A., Khamseh, Mohammad E., Kiely, Kim M., Kim, Sung-Wan, Kjærgaard, Marie, Kohlhoff, Jane, Kohrt, Brandon A., König, Hans-Helmut, Kozinszky, Zoltán, Kwan, Yunxin, Lamers, Femke, Lara, María Asunción, Leonardou, Angeliki A., Levin-Aspenson, Holly F., Liu, Shen-Ing, Löbner, Margrit, Loosman, Wim L., Lotrakul, Manote, Loureiro, Sonia R., Love, Anthony W., Löwe, Bernd, Luitel, Nagendra P., Lund, Crick, Maes, Michael, Malt, Ulrik F., Marrie, Ruth Ann, Marsh, Laura, Martínez, Pablo, Marx, Brian P., Matsuoka, Yutaka, McGuire, Anthony, Mehnert, Anja, Michopoulos, Ioannis, Sidik, Sherina Mohd, Müller-Nordhorn, Jacqueline, Muramatsu, Kumiko, Radoš, Sandra Nakić, Navarrete, Laura, Nelson, Christian J., Ng, Chong Guan, Nishi, Daisuke, O'Donnell, Meaghan L., O'Rourke, Suzanne J., Osório, Flávia L., Pabst, Alexander, Pasco, Julie A., Pawlby, Susan J., Peceliuniene, Jurate, Pence, Brian W., Persoons, Philippe, Petersen, Inge, Picardi, Angelo, Ponsford, Jennie L., Pugh, Stephanie L., Pulido, Federico, Quinn, Terence J., Quispel, Chantal, Rathod, Sujit D., Reme, Silje E., Reuter, Katrin, Riedel-Heller, Steffi G., Rooney, Alasdair G., Santos, Iná S., Saracino, Rebecca M., Schellekens, Melanie P.J., Schwarzbold, Marcelo L., Cankorur, Vesile Senturk, Shaaban, Juwita, Sharp, Deborah J., Sharpe, Louise, Shinn, Eileen H., Sidebottom, Abbey, Simard, Sébastien, Singer, Susanne, Skalkidou, Alkistis, Smith-Nielsen, Johanne, Spangenberg, Lena, Stafford, Lesley, Stein, Alan, Stewart, Robert C., Strobel, Natalie A., Su, Kuan-Pin, Sultan, Serge, Sundström-Poromaa, Inger, Sung, Sharon C., Suzuki, Keiko, Tadinac, Meri, Tan, Pei Lin Lynnette, Tandon, S. Darius, Taylor-Rowan, Martin, Teixeira, Antonio L., Tendais, Iva, Tiringer, Istvan, Töreki, Annamária, Tran, Thach D., Trevillion, Kylee, Tschorn, Mira, Turner, Alyna, Væver, Mette S., van der Feltz-Cornelis, Christina M., van Heyningen, Thandi, Vega-Dienstmaier, Johann M., Wagner, Michael, Wagner, Lynne I., Wang, Liang-Jen, Wang, Jian Li, Watson, David, Weyerer, Siegfried B., White, Jennifer, Whooley, Mary A., Wiese, Birgitt, Williams, Lana J., Winkley, Kirsty, Wynter, Karen, Yamada, Mitsuhiko, Yonkers, Kimberly A., Zeng, Qing Zhi, Zhang, Yuying, Harel, Daphna, Wu, Yin, Levis, Brooke, Fan, Suiqiong, Sun, Ying, Xu, Mingyao, Rice, Danielle B., Boruff, Jill, Markham, Sarah, Ioannidis, John P.A., Takwoingi, Yemisi, Patten, Scott B., Ziegelstein, Roy C., Cuijpers, Pim, Gilbody, Simon, Vigod, Simone, Akena, Dickens, Benedetti, Andrea, and Thombs, Brett D.

Published
2024
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7. Mental health stigma experiences among caregivers and service users in South Africa: a qualitative investigation

Author

Monnapula-Mazabane, Portia and Petersen, Inge

Subjects
Mental health -- Evaluation, Caregivers -- Beliefs, opinions and attitudes, Stigma (Social psychology) -- Analysis -- Management, Mental illness -- Diagnosis -- Care and treatment, Company business management, Psychology and mental health
Abstract

The study aimed to understand the nature and context of mental health stigma among people living with a mental health condition and the subsequent effect on their caregivers. Semi-structured qualitative face to face interviews were conducted by trained mental healthcare professionals with mental health service users (n = 26) and caregivers (n = 24) in private rooms at a tertiary health facility, where service users were admitted. Following transcription and translation, data was analysed using framework analysis. There was limited knowledge about their mental health diagnosis by service users and generally low mental health literacy among service users and caregivers. Mental health service users reported experiences of stigma from their own families and communities. Caregivers reported withholding the patient's diagnosis from the community for fear of being stigmatised, and this fear of stigma carries the risk of negatively affecting care treatment-seeking. Limited mental health knowledge, coupled with a high prevalence of perceived family and community stigma among caregivers and service users, impedes the capacity of caregivers to effectively cope in supporting their family members living with mental illness. There is a need for interventions to provide psychoeducation, reduce community stigma, and support coping strategies for caregivers and people with mental health conditions., Author(s): Portia Monnapula-Mazabane [sup.1] , Inge Petersen [sup.2] Author Affiliations: (1) grid.16463.36, 0000 0001 0723 4123, School of Applied Human Sciences, Discipline of Psychology, University of KwaZulu-Natal, , 4001, Durban, [...]

Published
2023
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9. Implementation of Integrated Care Models

Author

Kemp, Christopher, primary, Chwastiak, Lydia, additional, Petersen, Inge, additional, Bhana, Arvin, additional, Wagenaar, Bradley H., additional, Unützer, Jürgen, additional, and Rao, Deepa, additional

Published
2023
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20. Effect of Spironolactone on Kidney Function in Kidney Transplant Recipients: A Randomized Placebo-Controlled Clinical Trial

Author

Mortensen, Line A., primary, Jespersen, Bente, additional, Helligsoe, Anne Sophie L., additional, Tougaard, Birgitte, additional, Cibulskyte-Ninkovic, Donata, additional, Egfjord, Martin, additional, Boesby, Lene, additional, Marcussen, Niels, additional, Madsen, Kirsten, additional, Jensen, Boye L., additional, Petersen, Inge, additional, Bistrup, Claus, additional, and Thiesson, Helle C., additional

Published
2024
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21. Addressing a Threat to the Healthfulness of Tomorrow's Generation: The Case of Cigarette Smoking in Nigeria

Author

Egbe, Catherine O., Petersen, Inge, and Meyer-Weitz, Anna

Abstract

Cigarette smoking has widely received the attention of international and local health bodies. Efforts are being made towards curbing smoking prevalence globally with a view to reduce the health, economic and social effects of smoking in the society. While some developed countries are recording success in this effort mainly through stringent tobacco control policies and educating the public, Nigeria is yet to actively key into the WHO-Framework Convention on Tobacco Control (WHO-FCTC) which she signed in June 28 2004 ("Nigeria: Report card on the WHO-FCTC," n.d.). With the stalling of the process of formulating a viable tobacco control policy in Nigeria through politics and politicking, it is important that other strategies which will help in reducing smoking prevalence especially among the youth be explored. This article looks at the psychosocial risk influences for smoking among Nigerian youth with a view to inform educational and psychosocial interventions that can help to reduce smoking uptake by the youth.

Published
2014

22. Effectiveness of a task-sharing collaborative care model for identification and management of depressive symptoms in patients with hypertension attending public sector primary care clinics in South Africa: pragmatic parallel cluster randomised controlled trial.

Author

Petersen, Inge, Fairall, Lara, Zani, Babalwa, Bhana, Arvin, Lombard, Carl, Folb, Naomi, Selohilwe, One, Georgeu-Pepper, Daniella, Petrus, Ruwayda, Mntambo, Ntokozo, Kathree, Tasneem, Bachmann, Max, Levitt, Naomi, Thornicroft, Graham, and Lund, Crick

Published
2021
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25. Collaborative implementation of an evidence-based package of integrated primary mental healthcare using quality improvement within a learning health systems approach: Lessons from the Mental health INTegration programme in South Africa.

Author

Gigaba, Sithabisile Gugulethu, Luvuno, Zamasomi, Bhana, Arvin, van Rensburg, Andre Janse, Mthethwa, Londiwe, Rao, Deepa, Hongo, Nikiwe, and Petersen, Inge

Subjects
MENTAL health screening, MENTAL health services, HEALTH programs, MENTAL illness, MENTAL health, MEDICAL personnel
Abstract

Introduction: The treatment gap for mental health disorders persists in low- and middle-income countries despite overwhelming evidence of the efficacy of tasksharing mental health interventions. Key barriers in the uptake of these innovations include the absence of policy to support implementation and diverting of staff from usual routines in health systems that are already overstretched. South Africa enjoys a conducive policy environment; however, strategies for operationalizing the policy ideals are lacking. This paper describes the Mental health INTegration Programme (MhINT), which adopted a health system strengthening approach to embed an evidence-based task-sharing care package for depression to integrate mental health care into chronic care at primary health care (PHC). Methods: The MhINT care package consisting of psycho-education talks, nurse-led mental health assessment, and a structured psychosocial counselling intervention provided by lay counsellors was implemented in Amajuba district in KwaZulu-Natal over a 2-year period. A learning health systems approach was adopted, using continuous quality improvement (CQI) strategies to facilitate embedding of the intervention. MhINT was implemented along five phases: the project phase wherein teams to drive implementation were formed; the diagnostic phase where routinely collected data were used to identify system barriers to integrated mental health care; the intervention phase consisting of capacity building and using Plan-Do-Study-Act cycles to address implementation barriers and the impact and sustaining improvement phases entailed assessing the impact of the program and initiation of system-level interventions to sustain and institutionalize successful change ideas. Results: Integrated planning and monitoring were enabled by including key mental health service indicators in weekly meetings designed to track the performance of noncommunicable diseases and human immunovirus clinical programmes. Lack of standardization in mental health screening prompted the validation of a mental health screening tool and testing feasibility of its use in centralized screening stations. A culture of collaborative problem-solving was promoted through CQI data-driven learning sessions. The province-level screening rate increased by 10%, whilst the district screening rate increased by 7% and new patients initiated to mental health treatment increased by 16%. Conclusions: The CQI approach holds promise in facilitating the attainment of integrated mental health care in resource-scarce contexts. A collaborative relationship between researchers and health system stakeholders is an important strategy for facilitating the uptake of evidence-based innovations. However, the lack of interventions to address healthcare workers' own mental health poses a threat to integrated mental health care at PHC. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Task-sharing of psychological treatment for antenatal depression in Khayelitsha, South Africa: Effects on antenatal and postnatal outcomes in an individual randomised controlled trial

Author

Lund, Crick, Schneider, Marguerite, Garman, Emily C., Davies, Thandi, Munodawafa, Memory, Honikman, Simone, Bhana, Arvin, Bass, Judith, Bolton, Paul, Dewey, Michael, Joska, John, Kagee, Ashraf, Myer, Landon, Petersen, Inge, Prince, Martin, Stein, Dan J., Tabana, Hanani, Thornicroft, Graham, Tomlinson, Mark, Hanlon, Charlotte, Alem, Atalay, and Susser, Ezra

Published
2020
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30. Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis

Author

Levis, Brooke, Benedetti, Andrea, Ioannidis, John P.A., Sun, Ying, Negeri, Zelalem, He, Chen, Wu, Yin, Krishnan, Ankur, Bhandari, Parash Mani, Neupane, Dipika, Imran, Mahrukh, Rice, Danielle B., Riehm, Kira E., Saadat, Nazanin, Azar, Marleine, Boruff, Jill, Cuijpers, Pim, Gilbody, Simon, Kloda, Lorie A., McMillan, Dean, Patten, Scott B., Shrier, Ian, Ziegelstein, Roy C., Alamri, Sultan H., Amtmann, Dagmar, Ayalon, Liat, Baradaran, Hamid R., Beraldi, Anna, Bernstein, Charles N., Bhana, Arvin, Bombardier, Charles H., Carter, Gregory, Chagas, Marcos H., Chibanda, Dixon, Clover, Kerrie, Conwell, Yeates, Diez-Quevedo, Crisanto, Fann, Jesse R., Fischer, Felix H., Gholizadeh, Leila, Gibson, Lorna J., Green, Eric P., Greeno, Catherine G., Hall, Brian J., Haroz, Emily E., Ismail, Khalida, Jetté, Nathalie, Khamseh, Mohammad E., Kwan, Yunxin, Lara, Maria Asunción, Liu, Shen-Ing, Loureiro, Sonia R., Löwe, Bernd, Marrie, Ruth Ann, Marsh, Laura, McGuire, Anthony, Muramatsu, Kumiko, Navarrete, Laura, Osório, Flávia L., Petersen, Inge, Picardi, Angelo, Pugh, Stephanie L., Quinn, Terence J., Rooney, Alasdair G., Shinn, Eileen H., Sidebottom, Abbey, Spangenberg, Lena, Tan, Pei Lin Lynnette, Taylor-Rowan, Martin, Turner, Alyna, van Weert, Henk C., Vöhringer, Paul A., Wagner, Lynne I., White, Jennifer, Winkley, Kirsty, and Thombs, Brett D.

Published
2020
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31. Humoral antibody response following mRNA vaccines against SARS-CoV-2 in solid organ transplant recipients; a status after a fifth and bivalent vaccine dose

Author

Christophorou, Emma, primary, Nilsson, Anna Christine, additional, Petersen, Inge, additional, Lindvig, Susan O., additional, Davidsen, Jesper R., additional, Abazi, Rozeta, additional, Poulsen, Mikael K., additional, Pedersen, Rune M., additional, Justesen, Ulrik S., additional, Johansen, Nicolai E., additional, Bistrup, Claus, additional, Madsen, Lone W., additional, and Johansen, Isik S., additional

Published
2023
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32. Strengthening integrated depression services within routine primary health care using the RE-AIM framework in South Africa

Author

Petersen, Inge, primary, Kemp, Christopher G., additional, Rao, Deepa, additional, Wagenaar, Bradley H., additional, Bachmann, Max, additional, Sherr, Kenneth, additional, Kathree, Tasneem, additional, Luvuno, Zamasomi, additional, Van Rensburg, André, additional, Gigaba, Sithabisile Gugulethu, additional, Mthethwa, Londiwe, additional, Grant, Merridy, additional, Selohilwe, One, additional, Hongo, Nikiwe, additional, Faris, Gillian, additional, Ras, Christy-Joy, additional, Fairall, Lara, additional, Bucibo, Sanah, additional, and Bhana, Arvin, additional

Published
2023
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33. Collaborative implementation of an evidence‐based package of integrated primary mental healthcare using quality improvement within a learning health systems approach: Lessons from the Mental health INTegration programme in South Africa

Author

Gigaba, Sithabisile Gugulethu, primary, Luvuno, Zamasomi, additional, Bhana, Arvin, additional, Janse van Rensburg, Andre, additional, Mthethwa, Londiwe, additional, Rao, Deepa, additional, and Petersen, Inge, additional

Published
2023
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36. Age-moderation of genetic and environmental contributions to cognitive functioning in mid- and late-life for specific cognitive abilities

Author

Pahlen, Shandell, Hamdi, Nayla R., Dahl Aslan, Anna K., Horwitz, Briana N., Panizzon, Matthew S., Petersen, Inge, Zavala, Catalina, Christensen, Kaare, Finkel, Deborah, Franz, Carol E., Gatz, Margaret, Johnson, Wendy, Kremen, William S., Krueger, Robert F., Neiderhiser, Jenae M., Reynolds, Chandra A., Pedersen, Nancy L., and McGue, Matt

Published
2018
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37. Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.

Author

Mangino, Massimo, Hwang, Shih-Jen, Spector, Timothy, Hunt, Steven, Kimura, Masayuki, Fitzpatrick, Annette, Christiansen, Lene, Petersen, Inge, Elbers, Clara, Harris, Tamara, Chen, Wei, Srinivasan, Sathanur, Kark, Jeremy, Benetos, Athanase, El Shamieh, Said, Visvikis-Siest, Sophie, Christensen, Kaare, Berenson, Gerald, Valdes, Ana, Viñuela, Ana, Garcia, Melissa, Arnett, Donna, Broeckel, Ulrich, Province, Michael, Pankow, James, Kammerer, Candace, Liu, Yongmei, Nalls, Michael, Tishkoff, Sarah, Thomas, Fridtjof, Psaty, Bruce, Bis, Joshua, Taylor, Kent, Smith, Erin, Schork, Nicholas, Levy, Daniel, Aviv, Abraham, Ziv, Elad, and Rotter, Jerome

Subjects
Genome-Wide Association Study, Humans, Kruppel-Like Transcription Factors, Telomere, Telomere Homeostasis, Telomere-Binding Proteins
Abstract

Leukocyte telomere length (LTL) is associated with a number of common age-related diseases and is a heritable trait. Previous genome-wide association studies (GWASs) identified two loci on chromosomes 3q26.2 (TERC) and 10q24.33 (OBFC1) that are associated with the inter-individual LTL variation. We performed a meta-analysis of 9190 individuals from six independent GWAS and validated our findings in 2226 individuals from four additional studies. We confirmed previously reported associations with OBFC1 (rs9419958 P = 9.1 × 10(-11)) and with the telomerase RNA component TERC (rs1317082, P = 1.1 × 10(-8)). We also identified two novel genomic regions associated with LTL variation that map near a conserved telomere maintenance complex component 1 (CTC1; rs3027234, P = 3.6 × 10(-8)) on chromosome17p13.1 and zinc finger protein 676 (ZNF676; rs412658, P = 3.3 × 10(-8)) on 19p12. The minor allele of rs3027234 was associated with both shorter LTL and lower expression of CTC1. Our findings are consistent with the recent observations that point mutations in CTC1 cause short telomeres in both Arabidopsis and humans affected by a rare Mendelian syndrome. Overall, our results provide novel insights into the genetic architecture of inter-individual LTL variation in the general population.

Published
2012

39. Correction to: Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol

Author

Baron, Emily C., Rathod, Sujit D., Hanlon, Charlotte, Prince, Martin, Fedaku, Abebaw, Kigozi, Fred, Jordans, Mark, Luitel, Nagendra P., Medhin, Girmay, Murhar, Vaibhav, Nakku, Juliet, Patel, Vikram, Petersen, Inge, Selohilwe, One, Shidhaye, Rahul, Ssebunnya, Joshua, Tomlinson, Mark, Lund, Crick, and De Silva, Mary

Published
2020
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40. Implementing combined WHO mhGAP and adapted group interpersonal psychotherapy to address depression and mental health needs of pregnant adolescents in Kenyan primary health care settings (INSPIRE): a study protocol for pilot feasibility trial of the integrated intervention in LMIC settings

Author

Kumar, Manasi, Huang, Keng-Yen, Othieno, Caleb, Wamalwa, Dalton, Hoagwood, Kimberly, Unutzer, Jurgen, Saxena, Shekhar, Petersen, Inge, Njuguna, Simon, Amugune, Beatrice, Gachuno, Onesmus, Ssewamala, Fred, and McKay, Mary

Published
2020
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