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3,934 results on '"Petersen, Romina"'

1. The challenge of hypophosphatasia diagnosis in adults: results from the HPP International Working Group Literature Surveillance

Author

Brandi, Maria Luisa, Khan, Aliya A., Rush, Eric T., Ali, Dalal S., Al-Alwani, Hatim, Almonaei, Khulod, Alsarraf, Farah, Bacrot, Severine, Dahir, Kathryn M., Dandurand, Karel, Deal, Chad, Ferrari, Serge Livio, Giusti, Francesca, Guyatt, Gordon, Hatcher, Erin, Ing, Steven W., Javaid, Muhammad Kassim, Khan, Sarah, Kocijan, Roland, Lewiecki, E. Michael, Linglart, Agnes, M’Hiri, Iman, Marini, Francesca, Nunes, Mark E., Rockman-Greenberg, Cheryl, Seefried, Lothar, Simmons, Jill H., Starling, Susan R., Ward, Leanne M., Yao, Liang, Brignardello-Petersen, Romina, and Roux, Christian

Published
2024
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2. Hypophosphatasia diagnosis: current state of the art and proposed diagnostic criteria for children and adults

Author

Khan, Aliya A., Brandi, Maria Luisa, Rush, Eric T., Ali, Dalal S., Al-Alwani, Hatim, Almonaei, Khulod, Alsarraf, Farah, Bacrot, Severine, Dahir, Kathryn M., Dandurand, Karel, Deal, Chad, Ferrari, Serge Livio, Giusti, Francesca, Guyatt, Gordon, Hatcher, Erin, Ing, Steven W., Javaid, Muhammad Kassim, Khan, Sarah, Kocijan, Roland, Linglart, Agnes, M’Hiri, Iman, Marini, Francesca, Nunes, Mark E., Rockman-Greenberg, Cheryl, Roux, Christian, Seefried, Lothar, Simmons, Jill H., Starling, Susan R., Ward, Leanne M., Yao, Liang, Brignardello-Petersen, Romina, and Lewiecki, E. Michael

Published
2024
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6. Proposed diagnostic criteria for the diagnosis of hypophosphatasia in children and adolescents: results from the HPP International Working Group

Author

Rush, Eric, Brandi, Maria Luisa, Khan, Aliya, Ali, Dalal S., Al-Alwani, Hatim, Almonaei, Khulod, Alsarraf, Farah, Bacrot, Severine, Dahir, Kathryn M., Dandurand, Karel, Deal, Chad, Ferrari, Serge Livio, Giusti, Francesca, Guyatt, Gordon, Hatcher, Erin, Ing, Steven W., Javaid, Muhammad Kassim, Khan, Sarah, Kocijan, Roland, Lewiecki, E. Michael, Linglart, Agnes, M’Hiri, Iman, Marini, Francesca, Nunes, Mark E., Rockman-Greenberg, Cheryl, Roux, Christian, Seefried, Lothar, Starling, Susan R., Ward, Leanne, Yao, Liang, Brignardello-Petersen, Romina, and Simmons, Jill H.

Published
2024
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7. Correction: Hypophosphatasia diagnosis: current state of the art and proposed diagnostic criteria for children and adults

Author

Khan, Aliya A., Brandi, Maria Luisa, Rush, Eric T., Ali, Dalal S., Al-Alwani, Hatim, Almonaei, Khulod, Alsarraf, Farah, Bacrot, Severine, Dahir, Kathryn M., Dandurand, Karel, Deal, Chad, Ferrari, Serge Livio, Giusti, Francesca, Guyatt, Gordon, Hatcher, Erin, Ing, Steven W., Javaid, Muhammad Kassim, Khan, Sarah, Kocijan, Roland, Linglart, Agnes, M’Hiri, Iman, Marini, Francesca, Nunes, Mark E., Rockman-Greenberg, Cheryl, Roux, Christian, Seefried, Lothar, Simmons, Jill H., Starling, Susan R., Ward, Leanne M., Yao, Liang, Brignardello-Petersen, Romina, and Michael Lewiecki, E.

Published
2024
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8. GRADE guidance 39: using GRADE-ADOLOPMENT to adopt, adapt or create contextualized recommendations from source guidelines and evidence syntheses

Author

Klugar, Miloslav, Lotfi, Tamara, Darzi, Andrea J., Reinap, Marge, Klugarová, Jitka, Kantorová, Lucia, Xia, Jun, Brignardello-Petersen, Romina, Pokorná, Andrea, Hazlewood, Glen, Munn, Zachary, Morgan, Rebecca L., Toews, Ingrid, Neumann, Ignacio, Bhatarasakoon, Patraporn, Stein, Airton Tetelbom, McCaul, Michael, Mathioudakis, Alexander G., D'Anci, Kristen E., Leontiadis, Grigorios I., Naude, Celeste, Vasanthan, Lenny T., Khabsa, Joanne, Bala, Malgorzata M., Mustafa, Reem, DiValerio Gibbs, Karen, Nieuwlaat, Robby, Santesso, Nancy, Pieper, Dawid, Mokrane, Saphia, Soghier, Israa, Lertwatthanawilat, Wanchai, Wiercioch, Wojtek, Sultan, Shahnaz, Rozmarinová, Jana, Drapačová, Pavla, Song, Yang, Amer, Marwa, Amer, Yasser S., Sayfi, Shahab, Verstijnen, Ilse M., Shin, Ein-Soon, Saz-Parkinson, Zuleika, Pottie, Kevin, Ruspi, Alessandra, Marušić, Ana, Saif-Ur-Rahman, K.M., Rojas, Maria X., Akl, Elie A., and Schünemann, Holger J.

Published
2024
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11. Effect of low dose denosumab on bone mineral density in postmenopausal women with osteoporosis after a transition from 60 mg dose: a prospective observational study

Author

Khan, Aliya A., AbuAlrob, Hajar, M’Hiri, Iman, Ali, Dalal S., Dandurand, Karel, Said, Hosay, Alkassem, Hisham, Hakami, Yasser, Hweija, Ismail, Iqbal, Salman, Romanovschi, Mihai, Mehmood, Shehryar, Zariffeh, Heather, Guyatt, Gordon, Ibrahim, Quazi, Brignardello-Petersen, Romina, and Syed, Hamza I.

Published
2023
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13. American Society of Hematology living guidelines on use of anticoagulation for thromboprophylaxis for patients with COVID-19: executive summary

Author

Siegal, Deborah M., Tseng, Eric K., Schünemann, Holger J., Angchaisuksiri, Pantep, Cuker, Adam, Dane, Kathryn, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Terrell, Deirdra R., Akl, Elie A., Al Jabiri, Reyad, Al Jabiri, Yazan, Barbara, Angela M., Bognanni, Antonio, Akl, Imad Bou, Boulos, Mary, Brignardello-Petersen, Romina, Chan, Matthew, Charide, Rana, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Hussein, Heba, Karam, Samer G., Kolb, Philipp, Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Schünemann, Giovanna Muti, Nadim, Menatalla K., Noori, Atefeh, Philip, Binu A., Piggott, Thomas, Qiu, Yuan, Benitez, Yetiani Roldan, Schünemann, Finn, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Nieuwlaat, Robby

Published
2024
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14. Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors

Author

Wang, Ying, Parpia, Sameer, Couban, Rachel, Wang, Qi, Armijo-Olivo, Susan, Bassler, Dirk, Briel, Matthias, Brignardello-Petersen, Romina, Gluud, Lise Lotte, Keitz, Sheri A., Letelier, Luz M., Ravaud, Philippe, Schulz, Kenneth F., Siemieniuk, Reed A.C., Zeraatkar, Dena, and Guyatt, Gordon H.

Published
2024
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15. Efficacy and Safety of Pharmacologic Interventions in Patients Experiencing a Gout Flare: A Systematic Review and Network Meta-Analysis.

Author

Zeng, Linan, Qasim, Anila, Neogi, Tuhina, Dalbeth, Nicola, Mikuls, Ted, Guyatt, Gordon, Brignardello-Petersen, Romina, and FitzGerald, John

Subjects
Adult, Aged, Anti-Inflammatory Agents, Female, Gout, Gout Suppressants, Humans, Male, Middle Aged, Network Meta-Analysis, Randomized Controlled Trials as Topic, Remission Induction, Symptom Flare Up, Treatment Outcome
Abstract

OBJECTIVE: To compare the relative efficacy and safety of pharmacologic antiinflammatory interventions for gout flares. METHODS: We searched Ovid Medline, Embase, and Cochrane library for randomized controlled trials (RCTs) that compared pharmacologic antiinflammatory treatment of gout flares. We conducted a network meta-analysis (NMA) using a frequentist framework and assessed the certainty of evidence and made conclusions using the Grading of Recommendations Assessment, Development, and Evaluation for NMA. RESULTS: In the 30 eligible RCTs, canakinumab provided the highest pain reduction at day 2 and at longest follow-up (mean difference relative to acetic acid derivative nonsteroidal antiinflammatory drugs [NSAIDs] -41.12 [95% confidence interval (95% CI) -53.36, -29.11] on a 0-100 scale at day 2, and mean difference -12.84 [95% CI -20.76, -4.91] at longest follow-up; both moderate certainty; minimum important difference -19). Intravenous or intramuscular corticosteroids were inferior to canakinumab but may be better than the other commonly used interventions (low to very low certainty). For joint tenderness, canakinumab may be the most effective intervention at day 2. Acetic acid derivative NSAIDs improved joint swelling better than ibuprofen NSAIDs at day 2 (mean difference -0.29 [95% CI -0.56, -0.02] on a 0-4 scale; moderate certainty) and improved patient global assessment (PtGA) greater than ibuprofen NSAIDs at the longest follow-up (mean difference -0.44 [95% CI -0.86, -0.02]; moderate). CONCLUSION: Canakinumab may be superior to other alternatives and intravenous or intramuscular corticosteroids may be the second best in pain reduction. Acetic acid derivative NSAIDs may be superior to ibuprofen NSAIDs in improving joint swelling and PtGA.

Published
2021

16. Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials

Author

Chu, Derek K., Chu, Alexandro W.L., Rayner, Daniel G., Guyatt, Gordon H., Yepes-Nuñez, Juan José, Gomez-Escobar, Luis, Pérez-Herrera, Lucia C., Díaz Martinez, Juan Pablo, Brignardello-Petersen, Romina, Sadeghirad, Behnam, Wong, Melanie M., Ceccacci, Renata, Zhao, Irene X., Basmaji, John, MacDonald, Margaret, Chu, Xiajing, Islam, Nazmul, Gao, Ya, Izcovich, Ariel, Asiniwasis, Rachel N., Boguniewicz, Mark, De Benedetto, Anna, Capozza, Korey, Chen, Lina, Ellison, Kathy, Frazier, Winfred T., Greenhawt, Matthew, Huynh, Joey, LeBovidge, Jennifer, Lio, Peter A., Martin, Stephen A., O’Brien, Monica, Ong, Peck Y., Silverberg, Jonathan I., Spergel, Jonathan M., Smith Begolka, Wendy, Wang, Julie, Wheeler, Kathryn E., Gardner, Donna D., and Schneider, Lynda

Published
2023
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17. Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials

Author

Chu, Alexandro W.L., Wong, Melanie M., Rayner, Daniel G., Guyatt, Gordon H., Díaz Martinez, Juan Pablo, Ceccacci, Renata, Zhao, Irene X., McMullen, Eric, Srivastava, Archita, Wang, Jason, Wen, Aaron, Wang, Fang Chi, Brignardello-Petersen, Romina, Izcovich, Ariel, Oykhman, Paul, Wheeler, Kathryn E., Wang, Julie, Spergel, Jonathan M., Singh, Jasvinder A., Silverberg, Jonathan I., Ong, Peck Y., O’Brien, Monica, Martin, Stephen A., Lio, Peter A., Lind, Mary Laura, LeBovidge, Jennifer, Kim, Elaine, Huynh, Joey, Greenhawt, Matthew, Gardner, Donna D., Frazier, Winfred T., Ellison, Kathy, Chen, Lina, Capozza, Korey, De Benedetto, Anna, Boguniewicz, Mark, Smith Begolka, Wendy, Asiniwasis, Rachel N., Schneider, Lynda C., and Chu, Derek K.

Published
2023
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20. Equity issues rarely addressed in the development of COVID-19 formal recommendations and good practice statements: a cross-sectional study

Author

Dewidar, Omar, Bondok, Mostafa, Abdelrazeq, Leenah, Aliyeva, Khadija, Solo, Karla, Welch, Vivian, Brignardello-Petersen, Romina, Mathew, Joseph L., Hazlewood, Glen, Pottie, Kevin, Hartling, Lisa, Khalifa, Dina Sami, Duda, Stephanie, Falavigna, Maicon, Khabsa, Joanne, Lotfi, Tamara, Petkovic, Jennifer, Elliot, Sarah, Chi, Yuan, Parker, Roses, Kristjansson, Elizabeth, Riddle, Alison, Darzi, Andrea J., Magwood, Olivia, Saad, Ammar, Rada, Gabriel, Neumann, Ignacio, Loeb, Mark, Reveiz, Ludovic, Mertz, Dominik, Piggott, Thomas, Turgeon, Alexis F., Schünemann, Holger, and Tugwell, Peter

Published
2023
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25. 2020 American College of Rheumatology Guideline for the Management of Gout.

Author

Dalbeth, Nicola, Mikuls, Ted, Brignardello-Petersen, Romina, Guyatt, Gordon, Abeles, Aryeh, Gelber, Allan, Harrold, Leslie, Khanna, Dinesh, King, Charles, Levy, Gerald, Libbey, Caryn, Mount, David, Pillinger, Michael, Rosenthal, Ann, Singh, Jasvinder, Sims, James, Smith, Benjamin, Wenger, Neil, Bae, Sangmee, Danve, Abhijeet, Khanna, Puja, Kim, Seoyoung, Lenert, Aleksander, Poon, Samuel, Qasim, Anila, Sehra, Shiv, Sharma, Tarun, Toprover, Michael, Turgunbaev, Marat, Zeng, Linan, Zhang, Mary, Turner, Amy, Neogi, Tuhina, and FitzGerald, John

Subjects
Disease Management, Gout, Healthy Lifestyle, Humans, Symptom Flare Up, Uricosuric Agents
Abstract

OBJECTIVE: To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. METHODS: Fifty-seven population, intervention, comparator, and outcomes questions were developed, followed by a systematic literature review, including network meta-analyses with ratings of the available evidence according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology, and patient input. A group consensus process was used to compose the final recommendations and grade their strength as strong or conditional. RESULTS: Forty-two recommendations (including 16 strong recommendations) were generated. Strong recommendations included initiation of ULT for all patients with tophaceous gout, radiographic damage due to gout, or frequent gout flares; allopurinol as the preferred first-line ULT, including for those with moderate-to-severe chronic kidney disease (CKD; stage >3); using a low starting dose of allopurinol (≤100 mg/day, and lower in CKD) or febuxostat (

Published
2020

27. The GIN-McMaster guideline tool extension for the integration of quality improvement and quality assurance in guidelines: a description of the methods for its development

Author

Piggott, Thomas, Langendam, Miranda W., Parmelli, Elena, Adolfsson, Jan, Akl, Elie A., Armstrong, David, Braithwaite, Jeffrey, Brignardello-Petersen, Romina, Brozek, Jan, Follmann, Markus, Kopp, Ina, Meerpohl, Joerg J., Neamtiu, Luciana, Nothacker, Monika, Qaseem, Amir, Rossi, Paolo Giorgi, Saz-Parkinson, Zuleika, van der Wees, Philip J., and Schünemann, Holger J.

Published
2023
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29. Instruments assessing risk of bias of randomized trials frequently included items that are not addressing risk of bias issues

Author

Wang, Ying, Ghadimi, Maryam, Wang, Qi, Hou, Liangying, Zeraatkar, Dena, Iqbal, Atiya, Ho, Cameron, Yao, Liang, Hu, Malini, Ye, Zhikang, Couban, Rachel, Armijo-Olivo, Susan, Bassler, Dirk, Briel, Matthias, Gluud, Lise Lotte, Glasziou, Paul, Jackson, Rod, Keitz, Sheri A., Letelier, Luz M., Ravaud, Philippe, Schulz, Kenneth F., Siemieniuk, Reed A.C., Brignardello-Petersen, Romina, and Guyatt, Gordon H.

Published
2022
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30. GRADE guidance 35: update on rating imprecision for assessing contextualized certainty of evidence and making decisions

Author

Schünemann, Holger J., Neumann, Ignacio, Hultcrantz, Monica, Brignardello-Petersen, Romina, Zeng, Linan, Murad, M Hassan, Izcovich, Ariel, Morgano, Gian Paolo, Baldeh, Tejan, Santesso, Nancy, Cuello, Carlos Garcia, Mbuagbaw, Lawrence, Guyatt, Gordon, Wiercioch, Wojtek, Piggott, Thomas, De Beer, Hans, Vinceti, Marco, Mathioudakis, Alexander G., Mayer, Martin G., Mustafa, Reem, Filippini, Tommaso, Iorio, Alfonso, Nieuwlaat, Robby, Marcucci, Maura, Coello, Pablo Alonso, Bonovas, Stefanos, Piovani, Daniele, Tomlinson, George, and Akl, Elie A.

Published
2022
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32. Serious reporting deficiencies exist in minimal important difference studies: current state and suggestions for improvement

Author

Carrasco-Labra, Alonso, Devji, Tahira, Qasim, Anila, Phillips, Mark, Johnston, Bradley C., Devasenapathy, Niveditha, Zeraatkar, Dena, Bhatt, Meha, Jin, Xuejing, Brignardello-Petersen, Romina, Urquhart, Olivia, Foroutan, Farid, Schandelmaier, Stefan, Pardo-Hernandez, Hector, Vernooij, Robin WM., Huang, Hsiaomin, Rizwan, Yamna, Siemieniuk, Reed, Lytvyn, Lyubov, Patrick, Donald L., Ebrahim, Shanil, Furukawa, Toshi A., Nesrallah, Gihad, Schunemann, Holger J., Bhandari, Mohit, Thabane, Lehana, and Guyatt, Gordon H.

Published
2022
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34. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis for patients with COVID-19: March 2022 update on the use of anticoagulation in critically ill patients

Author

Cuker, Adam, Tseng, Eric K., Schünemann, Holger J., Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah M., Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Al Jabiri, Reyad, Al Jabiri, Yazan, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Karam, Samer G., Morgano, Gian Paolo, Morsi, Rami Z., Philip, Binu A., Benitez, Yetiani Roldan, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Nieuwlaat, Robby

Published
2022
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35. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: January 2022 update on the use of therapeutic-intensity anticoagulation in acutely ill patients

Author

Cuker, Adam, Tseng, Eric K., Nieuwlaat, Robby, Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah M., Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Al Jabiri, Reyad, Al Jabiri, Yazan, Barbara, Angela M., Bognanni, Antonio, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Hussein, Heba, Karam, Samer G., Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Muti-Schünemann, Giovanna, Nadim, Menatalla K., Philip, Binu A., Qiu, Yuan, Benitez, Yetiani Roldan, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Schünemann, Holger J.

Published
2022
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36. Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis

Author

Kalot, Mohamad A., Husainat, Nedaa, Abughanimeh, Omar, Diab, Osama, El Alayli, Abdallah, Tayiem, Sammy, Madoukh, Bader, Dimassi, Ahmad, Qureini, Aref, Ameer, Barbara, Eikenboom, Jeroen, Giraud, Nicolas, Haberichter, Sandra, Jacobs-Pratt, Vicky, Konkle, Barbara A., McRae, Simon, Montgomery, Robert, O'Donnell, James S., Brignardello-Petersen, Romina, Flood, Veronica, Connell, Nathan T., James, Paula, and Mustafa, Reem A.

Published
2022
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37. Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis.

Author

Rayner, Daniel G., Ferri, Dario M., Guyatt, Gordon H., O'Byrne, Paul M., Brignardello-Petersen, Romina, Foroutan, Farid, Chipps, Bradley, Sumino, Kaharu, Perry, Tamara T., Nyenhuis, Sharmilee, Oppenheimer, John, Israel, Elliot, Hoyte, Flavia, Rivera-Spoljaric, Katherine, McCabe, Ellen, Rangel, Susana, Shade, Lindsay E., Press, Valerie G., Hall, Lisa, and Sue-Wah-Sing, Dia

Abstract

Key Points: Question: In people with asthma, compared with short-acting β agonists (SABA) alone, is the combination of SABA with inhaled corticosteroids (ICS-SABA) and the combination of formoterol with inhaled corticosteroids (ICS-formoterol) associated with better asthma outcomes? Findings: In this systematic review and network meta-analysis that included 27 randomized clinical trials (50 496 adult and pediatric patients), compared with SABA alone, ICS-SABA was associated with a 4.7% reduction in risk of severe exacerbations and ICS-formoterol was associated with a 10.3% reduction in severe exacerbations, without an increase in adverse events. Meaning: Both combined ICS with SABA and ICS with formoterol were associated with lower risks of severe asthma exacerbations compared with SABA alone. Importance: The optimal inhaled reliever therapy for asthma remains unclear. Objective: To compare short-acting β agonists (SABA) alone with SABA combined with inhaled corticosteroids (ICS) and with the fast-onset, long-acting β agonist formoterol combined with ICS for asthma. Data Sources: The MEDLINE, Embase, and CENTRAL databases were searched from January 1, 2020, to September 27, 2024, without language restrictions. Study Selection: Pairs of reviewers independently selected randomized clinical trials evaluating (1) SABA alone, (2) ICS with formoterol, and (3) ICS with SABA (combined or separate inhalers). Data Extraction and Synthesis: Two reviewers independently extracted data and assessed risk of bias. Random-effects meta-analyses synthesized outcomes. GRADE (Grading of Recommendations Assessment, Development, and Evaluation) was used to evaluate the certainty of evidence. Main Outcomes and Measures: Asthma symptom control (5-item Asthma Control Questionnaire; range, 0-6, lower scores indicate better asthma control; minimum important difference [MID], 0.5 points), asthma-related quality of life (Asthma Quality of Life Questionnaire; range, 1-7, higher scores indicate better quality of life; MID, 0.5 points), risk of severe exacerbations, and risk of serious adverse events. Results: A total of 27 randomized clinical trials (N = 50 496 adult and pediatric patients; mean age, 41.0 years; 20 288 male [40%]) were included. Compared with SABA alone, both ICS-containing relievers were associated with fewer severe exacerbations (ICS-formoterol risk ratio [RR], 0.65 [95% CI, 0.60-0.72]; risk difference [RD], −10.3% [95% CI, −11.8% to −8.3%]; ICS-SABA RR, 0.84 [95% CI, 0.73-0.95]; RD, −4.7% [95% CI, −8.0% to −1.5%]) with high certainty. Compared with SABA alone, both ICS-containing relievers were associated with improved asthma control (ICS-formoterol RR improvement [MID] in total score, 1.07 [95% CI, 1.04-1.10]; RD, 4.1% [95% CI, 2.3%-5.9%]; ICS-SABA RR, 1.09 [95% CI, 1.03-1.15]; RD, 5.4% [95% CI, 1.8%-8.5%]) with high certainty. In an indirect comparison with ICS-SABA, ICS-formoterol was associated with fewer severe exacerbations (RR, 0.78 [95% CI, 0.66-0.92]; RD, −5.5% [95% CI, −8.4% to −2.0%]) with moderate certainty. Compared with SABA alone, ICS-formoterol (RD, −0.6% [95% CI, −1.3% to 0%]) was not associated with increased risk of serious adverse events (high certainty) and ICS-SABA (RD, 0% [95% CI, −1.1% to 1.2%]) was not associated with increased risk of serious adverse events (moderate certainty). Conclusions and Relevance: In this network meta-analysis of patients with asthma, ICS combined with formoterol and ICS combined with SABA were each associated with reduced asthma exacerbations and improved asthma control compared with SABA alone. This systematic review and network meta-analysis investigates whether inhaled corticosteroids combined with either short-acting beta agonists or formoterol are more effective than short-acting beta agonists alone in reducing exacerbations and improving control in patients with asthma. [ABSTRACT FROM AUTHOR]

Published
2025
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38. Outpatient vs inpatient management of preterm prelabor rupture of membranes: A systematic review and meta‐analysis.

Author

Williamson, Monica, Dong, Susan, D'Souza, Rohan, Brignardello‐Petersen, Romina, and Ronzoni, Stefania

Subjects
PREMATURE rupture of fetal membranes, RESPIRATORY distress syndrome, PREGNANT women, PREGNANCY complications, RANDOM effects model, CHORIOAMNIONITIS
Abstract

Introduction: To compare neonatal, obstetrical, and maternal outcomes associated with outpatient vs inpatient management of pregnancies with preterm prelabor rupture of membranes (PPROM). Material and Methods: A search of MEDLINE, EMBASE, the Cochrane Database and Central Register from January 1, 1990 to July 31, 2023 identified randomized controlled trials (RCTs) and cohort studies comparing outpatient with inpatient management for pregnant persons diagnosed with PPROM before 37 weeks' gestation. No language restriction was applied. We applied a random effects model for meta‐analysis. Trustworthiness was assessed using recently published guidance and Risk of bias using the RoB 2.0 tool for RCTs and ROBINS‐I tool for cohort studies. The Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach was used to assess the certainty of evidence (COE). Outcomes of interest included perinatal mortality, neonatal morbidities, latency and gestational age at delivery, and maternal morbidities. RCTs and cohort studies were analyzed separately. This study was registered in the International Prospective Register of Systematic Reviewsr: CRD42022295275. Results: From 2825 records, two RCTs and 10 cohort studies involving 1876 patients were included in the review and meta‐analysis. Outpatient management protocols varied but generally included brief initial hospitalization, strict eligibility criteria, and surveillance with laboratory and ultrasound investigations. Outpatient management showed lower rates of neonatal respiratory distress syndrome (cohort: RR 0.63 [0.52–0.77, very low COE]), longer latency to delivery (RCT: MD 7.43 days [1.14–13.72 days, moderate COE], cohort: MD 8.78 days [2.29–15.26 days, low COE]), higher gestational age at birth (cohort: MD 7.70 days [2.02–13.38 days, low COE]), lower rates of Apgar scores <7 at 5 min of life (cohort: RR 0.66 [0.50–0.89, very low COE]), and lower rates of histological chorioamnionitis (cohort: RR 0.74 [0.62–0.89, low COE]) without increased risks of adverse neonatal, obstetrical, or maternal outcomes. Conclusions: Meta‐analysis of data from RCTs and cohort studies with very low‐to‐moderate certainty of evidence indicates that further high‐quality research is needed to evaluate the safety and potential benefits of outpatient management for selected PPROM cases, given the moderate‐to‐high risk of bias in the included studies. [ABSTRACT FROM AUTHOR]

Published
2024
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41. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: July 2021 update on postdischarge thromboprophylaxis

Author

Cuker, Adam, Tseng, Eric K., Nieuwlaat, Robby, Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, Davila, Jennifer, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah, Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Al Jabiri, Reyad Nayif, Al Jabiri, Yazan Nayif, Barbara, Angela M., Bognanni, Antonio, Bou Akl, Imad, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Chan, Matthew, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Hussein, Heba, Karam, Samer G., Kolb, Philipp, Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Muti-Schünemann, Giovanna, Nadim, Menatalla K., Noori, Atefeh, Philip, Binu A., Piggott, Thomas, Qiu, Yuan, Benitez, Yetiani Roldan, Schünemann, Finn, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Schünemann, Holger J.

Published
2022
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42. Gynecologic and obstetric management of women with von Willebrand disease: summary of 3 systematic reviews of the literature

Author

Brignardello-Petersen, Romina, El Alayli, Abdallah, Husainat, Nedaa, Kalot, Mohamad A., Shahid, Shaneela, Aljabirii, Yazan, Britt, Alec, Alturkmani, Hani, El-Khechen, Hussein, Motaghi, Shahrzad, Roller, John, Abdul-Kadir, Rezan, Couper, Susie, Kouides, Peter, Lavin, Michelle, Ozelo, Margareth C., Weyand, Angela, James, Paula D., Connell, Nathan T., Flood, Veronica H., and Mustafa, Reem A.

Published
2022
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43. Surgical management of patients with von Willebrand disease: summary of 2 systematic reviews of the literature

Author

Brignardello-Petersen, Romina, El Alayli, Abdallah, Husainat, Nedaa, Kalot, Mohamad, Shahid, Shaneela, Aljabirii, Yazan, Britt, Alec, Alturkmani, Hani, El-Khechen, Hussein, Motaghi, Shahrzad, Roller, John, Dimassi, Ahmad, Abughanimeh, Omar, Madoukh, Bader, Arapshian, Alice, Grow, Jean M., Kouides, Peter, Laffan, Michael, Leebeek, Frank W.G., O'Brien, Sarah H., Tosetto, Alberto, James, Paula D., Connell, Nathan T., Flood, Veronica, and Mustafa, Reem A.

Published
2022
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44. von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis

Author

Kalot, Mohamad A., Husainat, Nedaa, El Alayli, Abdallah, Abughanimeh, Omar, Diab, Osama, Tayiem, Sammy, Madoukh, Bader, Dimassi, Ahmad B., Qureini, Aref, Ameer, Barbara, Eikenboom, Jeroen C.J., Giraud, Nicolas, McLintock, Claire, McRae, Simon, Montgomery, Robert R., O'Donnell, James S., Scappe, Nikole, Sidonio, Robert F., Jr, Brignardello-Petersen, Romina, Flood, Veronica H., Connell, Nathan T., James, Paula D., and Mustafa, Reem A.

Published
2022
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45. A taxonomy and framework for identifying and developing actionable statements in guidelines suggests avoiding informal recommendations

Author

Lotfi, Tamara, Hajizadeh, Anisa, Moja, Lorenzo, Akl, Elie A., Piggott, Thomas, Kredo, Tamara, Langendam, Miranda W., Iorio, Alfonso, Klugar, Miloslav, Klugarová, Jitka, Neumann, Ignacio, Wiercioch, Wojtek, Leontiadis, Grigorios I., Mbuagbaw, Lawrence, Turgeon, Alexis F., Meerpohl, Joerg, Stevens, Adrienne, Brozek, Jan, Santesso, Nancy, Pottie, Kevin, Dewidar, Omar, Flottorp, Signe A., Karpusheff, Justine, Saz-Parkinson, Zuleika, Rojas, María X., Parmelli, Elena, Chu, Derek K., Tugwell, Peter, Welch, Vivian, Avey, Marc T., Brignardello-Petersen, Romina, Mathew, Joseph L., Munn, Zachary, Nieuwlaat, Robby, Ford, Nathan, Qaseem, Amir, Askie, Lisa M., and Schünemann, Holger J.

Published
2022
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46. Bleeding assessment tools in the diagnosis of VWD in adults and children: a systematic review and meta-analysis of test accuracy

Author

Kalot, Mohamad A., Husainat, Nedaa, Tayiem, Sammy, El Alayli, Abdallah, Dimassi, Ahmad B., Diab, Osama, Abughanimeh, Omar, Madoukh, Bader, Qureini, Aref, Ameer, Barbara, Di Paola, Jorge, Eikenboom, Jeroen C.J., Jacobs-Pratt, Vicky, McLintock, Claire, Montgomery, Robert, O'Donnell, James S., Sidonio, Robert, Jr., Brignardello-Petersen, Romina, Flood, Veronica, Connell, Nathan T., James, Paula D., and Mustafa, Reem A.

Published
2021
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48. Clinical trials in COVID-19 management & prevention: A meta-epidemiological study examining methodological quality

Author

Honarmand, Kimia, Penn, Jeremy, Agarwal, Arnav, Siemieniuk, Reed, Brignardello-Petersen, Romina, Bartoszko, Jessica J., Zeraatkar, Dena, Agoritsas, Thomas, Burns, Karen, Fernando, Shannon M., Foroutan, Farid, Ge, Long, Lamontagne, Francois, Jimenez-Mora, Mario A., Murthy, Srinivas, Yepes-Nuñez, Juan Jose, Vandvik, Per O., Ye, Zhikang, and Rochwerg, Bram

Published
2021
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