15 results on '"Pettinari, Aldo"'
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2. Italian pool of asbestos workers cohorts : mortality trends of asbestos-related neoplasms after long time since first exposure
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Ferrante, Daniela, Chellini, Elisabetta, Merler, Enzo, Pavone, Venere, Silvestri, Stefano, Miligi, Lucia, Gorini, Giuseppe, Bressan, Vittoria, Girardi, Paolo, Ancona, Laura, Romeo, Elisa, Luberto, Ferdinando, Sala, Orietta, Scarnato, Corrado, Menegozzo, Simona, Oddone, Enrico, Tunesi, Sara, Perticaroli, Patrizia, Pettinari, Aldo, Cuccaro, Francesco, Mattioli, Stefano, Baldassarre, Antonio, Barone-Adesi, Francesco, Cena, Tiziana, Legittimo, Patrizia, Marinaccio, Alessandro, Mirabelli, Dario, Musti, Marina, Pirastu, Roberta, Ranucci, Alessandra, and Magnani, Corrado
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- 2017
3. Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy
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Luberto, Ferdinando, Ferrante, Daniela, Silvestri, Stefano, Angelini, Alessia, Cuccaro, Francesco, Nannavecchia, Anna Maria, Oddone, Enrico, Vicentini, Massimo, Barone-Adesi, Francesco, Cena, Tiziana, Mirabelli, Dario, Mangone, Lucia, Roncaglia, Francesca, Sala, Orietta, Menegozzo, Simona, Pirastu, Roberta, Azzolina, Danila, Tunesi, Sara, Chellini, Elisabetta, Miligi, Lucia, Perticaroli, Patrizia, Pettinari, Aldo, Bressan, Vittoria, Merler, Enzo, Girardi, Paolo, Bisceglia, Lucia, Marinaccio, Alessandro, Massari, Stefania, Magnani, Corrado, and the working group
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- 2019
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4. Rate advancement measurement for lung cancer and pleural mesothelioma in asbestos-exposed workers
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Azzolina, Danila, primary, Consonni, Dario, additional, Ferrante, Daniela, additional, Mirabelli, Dario, additional, Silvestri, Stefano, additional, Luberto, Ferdinando, additional, Angelini, Alessia, additional, Cuccaro, Francesco, additional, Nannavecchia, Anna Maria, additional, Oddone, Enrico, additional, Vicentini, Massimo, additional, Barone-Adesi, Francesco, additional, Cena, Tiziana, additional, Mangone, Lucia, additional, Roncaglia, Francesca, additional, Sala, Orietta, additional, Menegozzo, Simona, additional, Pirastu, Roberta, additional, Tunesi, Sara, additional, Chellini, Elisabetta, additional, Miligi, Lucia, additional, Perticaroli, Patrizia, additional, Pettinari, Aldo, additional, Bressan, Vittoria, additional, Merler, Enzo, additional, Girardi, Paolo, additional, Bisceglia, Lucia, additional, Marinaccio, Alessandro, additional, Massari, Stefania, additional, and Magnani, Corrado, additional
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- 2022
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5. Rate advancement measurement for lung cancer and pleural mesothelioma in asbestos-exposed workers
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Azzolina, Danila, Consonni, Dario, Ferrante, Daniela, Mirabelli, Dario, Silvestri, Stefano, Luberto, Ferdinando, Angelini, Alessia, Cuccaro, Francesco, Nannavecchia, Anna Maria, Oddone, Enrico, Vicentini, Massimo, Barone-Adesi, Francesco, Cena, Tiziana, Mangone, Lucia, Roncaglia, Francesca, Sala, Orietta, Menegozzo, Simona, Pirastu, Roberta, Tunesi, Sara, Chellini, Elisabetta, Miligi, Lucia, Perticaroli, Patrizia, Pettinari, Aldo, Bressan, Vittoria, Merler, Enzo, Girardi, Paolo, Bisceglia, Lucia, Marinaccio, Alessandro, Massari, Stefania, and Magnani, Corrado
- Abstract
IntroductionExposure to asbestos increases the risk of lung cancer and mesothelioma. Few studies quantified the premature occurrence of these diseases in asbestos-exposed workers. Focus on premature disease onset (rate advancement or acceleration) can be useful in risk communication and for the evaluation of exposure impact. We estimated rate advancement for total mortality, lung cancer and pleural mesothelioma deaths, by classes of cumulative asbestos exposure in a pooled cohort of asbestos cement (AC) workers in Italy.MethodThe cohort study included 12 578 workers from 21 cohorts, with 6626 deaths in total, 858 deaths from lung cancer and 394 from pleural malignant neoplasm (MN). Rate advancement was estimated by fitting a competitive mortality Weibull model to the hazard of death over time since first exposure (TSFE).ResultAcceleration time (AT) was estimated at different TSFE values. The highest level of cumulative exposure compared with the lowest, for pleural MN AT was 16.9 (95% CI 14.9 to 19.2) and 33.8 (95% CI 29.8 to 38.4) years at TSFE of 20 and 40 years, respectively. For lung cancer, it was 13.3 (95% CI 12.0 to 14.7) and 26.6 (95% CI 23.9 to 29.4) years, respectively. As for total mortality, AT was 3.35 (95% CI 2.98 to 3.71) years at 20 years TSFE, and 6.70 (95% CI 5.95 to 7.41) at 40 years TSFE.ConclusionThe current study observed marked rate advancement after asbestos exposure for lung cancer and pleural mesothelioma, as well as for total mortality.
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- 2023
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6. Factors Affecting Asbestosis Mortality Among Asbestos-Cement Workers in Italy
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Girardi, Paolo, primary, Merler, Enzo, primary, Ferrante, Daniela, primary, Silvestri, Stefano, primary, Chellini, Elisabetta, primary, Angelini, Alessia, primary, Luberto, Ferdinando, primary, Fedeli, Ugo, primary, Oddone, Enrico, primary, Vicentini, Massimo, primary, Barone-Adesi, Francesco, primary, Cena, Tiziana, primary, Mirabelli, Dario, primary, Mangone, Lucia, primary, Roncaglia, Francesca, primary, Sala, Orietta, primary, Menegozzo, Simona, primary, Pirastu, Roberta, primary, Azzolina, Danila, primary, Tunesi, Sara, primary, Miligi, Lucia, primary, Perticaroli, Patrizia, primary, Pettinari, Aldo, primary, Cuccaro, Francesco, primary, Nannavecchia, Anna Maria, primary, Bisceglia, Lucia, primary, Marinaccio, Alessandro, primary, Pavone, Venere Leda Mara, primary, and Magnani, Corrado, primary
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- 2020
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7. Additional file 1: of Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy
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Luberto, Ferdinando, Ferrante, Daniela, Silvestri, Stefano, Angelini, Alessia, Cuccaro, Francesco, Nannavecchia, Anna, Oddone, Enrico, Vicentini, Massimo, Barone-Adesi, Francesco, Cena, Tiziana, Mirabelli, Dario, Mangone, Lucia, Roncaglia, Francesca, Sala, Orietta, Menegozzo, Simona, Pirastu, Roberta, Azzolina, Danila, Tunesi, Sara, Chellini, Elisabetta, Miligi, Lucia, Perticaroli, Patrizia, Pettinari, Aldo, Bressan, Vittoria, Merler, Enzo, Girardi, Paolo, Bisceglia, Lucia, Marinaccio, Alessandro, Massari, Stefania, and Magnani, Corrado
- Abstract
Table S1. Asbestos cement pooled Italian study. Summary of cohort data, including all subjects, including those with follow-up terminated before 1970. Table S2. Asbestos cement pooled Italian study. Cause of death codes according to ICD in use at the date of death. Table S3. Asbestos cement pooled Italian study. Average asbestos exposure index, crude and adjusted for carcinogenic potency of asbestos types used, by cohort. Table S4. Asbestos cement pooled Italian study. Person-years at risk by gender and age class. Table S5. Asbestos cement pooled Italian study. Mortality by gender and duration of employment for selected causes of death. Table S6. Asbestos cement pooled Italian study. Mortality by gender and period of first exposure for selected causes of death. (PDF 646 kb)
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- 2019
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8. Role of asbestos clearance in explaining long-term risk of pleural and peritoneal cancer: a pooled analysis of cohort studies
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Barone-Adesi, Francesco, primary, Ferrante, Daniela, additional, Chellini, Elisabetta, additional, Merler, Enzo, additional, Pavone, Venere, additional, Silvestri, Stefano, additional, Miligi, Lucia, additional, Gorini, Giuseppe, additional, Bressan, Vittoria, additional, Girardi, Paolo, additional, Ancona, Laura, additional, Romeo, Elisa, additional, Luberto, Ferdinando, additional, Sala, Orietta, additional, Scarnato, Corrado, additional, Menegozzo, Simona, additional, Oddone, Enrico, additional, Tunesi, Sara, additional, Perticaroli, Patrizia, additional, Pettinari, Aldo, additional, Cuccaro, Francesco, additional, Curti, Stefania, additional, Baldassarre, Antonio, additional, Cena, Tiziana, additional, Angelini, Alessia, additional, Marinaccio, Alessandro, additional, Mirabelli, Dario, additional, Musti, Marina, additional, Pirastu, Roberta, additional, Ranucci, Alessandra, additional, and Magnani, Corrado, additional
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- 2019
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9. Valutazione della variazione temporale del rischio di mesotelioma e di tumore del polmone nelle coorti di esposti ad amianto per lavoro in Italia
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Magnani, Corrado, Ancona, Laura, Baldassarre, Antonio, Bressan, Vittoria, Cena, Tiziana, Chellini, Elisabetta, Cuccaro, Francesco, Ferrante, Daniela, Legittimo, Patrizia, Luberto, Ferdinando, Marinaccio, Alessandro, Mattioli, Stefano, Menegozzo, Simona, Merler, Enzo, Miligi, Lucia, Mirabelli, Dario, Musti, Marina, Oddone, Enrico, Pavone, Venere, Perticaroli, Patrizia, Pettinari, Aldo, Pirastu, Roberta, Ranucci, Alessandra, Romeo, Elisa, Sala, Orietta, Scarnato, Corrado, Silvestri, Stefano, Curti, Stefania, Magnani, Corrado, Ancona, Laura, Baldassarre, Antonio, Bressan, Vittoria, Cena, Tiziana, Chellini, Elisabetta, Cuccaro, Francesco, Ferrante, Daniela, Legittimo, Patrizia, Luberto, Ferdinando, Marinaccio, Alessandro, Mattioli, Stefano, Menegozzo, Simona, Merler, Enzo, Miligi, Lucia, Mirabelli, Dario, Musti, Marina, Oddone, Enrico, Pavone, Venere, Perticaroli, Patrizia, Pettinari, Aldo, Pirastu, Roberta, Ranucci, Alessandra, Romeo, Elisa, Sala, Orietta, Scarnato, Corrado, Silvestri, Stefano, [.., Curti, Stefania, and ]
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Male ,Mesothelioma ,Lung Neoplasms ,Epidemiology ,Environmental and Occupational Health ,Asbestosi ,Public Health, Environmental and Occupational Health ,Socio-culturale ,Ambientale ,Asbesto ,Asbestos ,Occupational Disease ,Lung Neoplasm ,Occupational Diseases ,Economica ,Italy ,Occupational Exposure ,Asbestosis ,Humans ,Female ,Public Health ,Human - Abstract
This study aims at investigating, in asbestos exposed workers, the time trend of their risk of mesothelioma and of other neoplasm after very long latency and after the cessation of asbestos exposure. We pooled a large number of Italian cohorts of asbestos workers and updated mortality follow-up. The pool of data for statistical analyses includes 51,988 workers, of which 6,058 women: 54.2% was alive at follow-up, 42.6% was dead, and 2.8%was lost. Cause of death is known for 94.3%: 2,548 deaths from lung cancer, 748 frompleural cancer, 173 fromperitoneal cancer, and 434 from asbestosis. An exposure index is being developed to compare the different cohorts. Data analysis is in progress. This study will have the size for analysing not only time trends in mesothelioma, but also the occurrence of rarer diseases and cancer specific mortality in women.
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- 2016
10. O32-3 A pooled cohort study on cancer risk among former asbestos-exposed workers: role of asbestos clearance in explaining long-term mortality trend for pleural cancer
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Magnani, Corrado, primary, Barone-Adesi, Francesco, additional, Ferrante, Daniela, additional, Ancona, Laura, additional, Baldassarre, Antonio, additional, Bressan, Vittoria, additional, Cena, Tizian, additional, Chellini, Elisabetta, additional, Cuccaro, Francesco, additional, Legittimo, Patrizia, additional, Luberto, Ferdinando, additional, Marinaccio, Alessandro, additional, Mattioli, Stefano, additional, Menegozzo, Simona, additional, Merler, Enzo, additional, Miligi, Lucia, additional, Mirabelli, Dario, additional, Musti, Marina, additional, Oddone, Enrico, additional, Pavone, Venere, additional, Perticaroli, Patrizia, additional, Pettinari, Aldo, additional, Pirastu, Roberta, additional, Ranucci, Alessandra, additional, Romeo, Elisa, additional, Sala, Orietta, additional, Scarnato, Corrado, additional, Silvestri, Stefano, additional, and W, G, additional
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- 2016
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11. A pooled cohort analysis on cancer risk among former asbestos-exposed workers: role of asbestos clearance in explaining long-term mortality trend for pleural cancer.
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Magnani, Corrado, primary, Barone-Adesi*, Francesco, additional, Ferrante, Daniela, additional, Ancona, Laura, additional, Baldassarre, Antonio, additional, Bressan, Vittoria, additional, Cena, Tiziana, additional, Chellini, Elisabetta, additional, Cuccaro, Francesco, additional, Legittimo, Patrizia, additional, Luberto, Ferdinando, additional, Marinaccio, Alessandro, additional, Mattioli, Stefano, additional, Menegozzo, Simona, additional, Merler, Enzo, additional, Miligi, Lucia, additional, Mirabelli, Dario, additional, Musti, Marina, additional, Oddone, Enrico, additional, Pavone, Venere, additional, Perticaroli, Patrizia, additional, Pettinari, Aldo, additional, Pirastu, Roberta, additional, Ranucci, Alessandra, additional, Romeo, Elisa, additional, Sala, Orietta, additional, Scarnato, Corrado, additional, Silvestri, Stefano, additional, and Group, Working, additional
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- 2016
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12. Time trend in mesothelioma and lung cancer risk in asbestos workers in Italy
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Magnani, Corrado, Ancona, Laura, Baldassarre, Antonio, Bressan, Vittoria, Cena, Tiziana, Chellini, Elisabetta, Cuccaro, Francesco, Ferrante, Daniela, Legittimo, Patrizia, Ferdinando Luberto, Marinaccio, Alessandro, Mattioli, Stefano, Menegozzo, Simona, Merler, Enzo, Miligi, Lucia, Mirabelli, Dario, Musti, Marina, Oddone, Enrico, Pavone, Venere, Perticaroli, Patrizia, Pettinari, Aldo, Pirastu, Roberta, Ranucci, Alessandra, Romeo, Elisa, Sala, Orietta, Scarnato, Corrado, and Silvestri, Stefano
13. Italian pool of asbestos workers cohorts: Mortality trends of asbestos-related neoplasms after long time since first exposure
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Simona Menegozzo, Dario Mirabelli, Francesco Cuccaro, Orietta Sala, Francesco Barone-Adesi, Daniela Ferrante, Vittoria Bressan, Lucia Miligi, Alessandro Marinaccio, Aldo Pettinari, Corrado Magnani, Paolo Girardi, Enzo Merler, Elisabetta Chellini, Venere Pavone, Alessandra Ranucci, Enrico Oddone, Patrizia Legittimo, Stefano Mattioli, Corrado Scarnato, Stefano Silvestri, Sara Tunesi, Laura Ancona, Patrizia Perticaroli, Roberta Pirastu, Marina Musti, Antonio Baldassarre, Tiziana Cena, Giuseppe Gorini, Elisa Romeo, Ferdinando Luberto, Ferrante, Daniela, Chellini, Elisabetta, Merler, Enzo, Pavone, Venere, Silvestri, Stefano, Miligi, Lucia, Gorini, Giuseppe, Bressan, Vittoria, Girardi, Paolo, Ancona, Laura, Romeo, Elisa, Luberto, Ferdinando, Sala, Orietta, Scarnato, Corrado, Menegozzo, Simona, Oddone, Enrico, Tunesi, Sara, Perticaroli, Patrizia, Pettinari, Aldo, Cuccaro, Francesco, Mattioli, Stefano, Baldassarre, Antonio, Barone-Adesi, Francesco, Cena, Tiziana, Legittimo, Patrizia, Marinaccio, Alessandro, Mirabelli, Dario, Musti, Marina, Pirastu, Roberta, Ranucci, Alessandra, Magnani, Corrado, [.., Curti, Stefania, and ]
- Subjects
Male ,Mesothelioma ,Occupational cancer ,Lung Neoplasms ,Asbestosis ,medicine.disease_cause ,Cohort Studies ,Economica ,0302 clinical medicine ,Cause of Death ,PLEURAL MESOTHELIOMA ,TEXTILE WORKERS ,Pleural Neoplasm ,Lung ,Peritoneal Neoplasms ,Cause of death ,LARYNGEAL-CANCER-MORTALITY ,RISK ,Ovarian Neoplasms ,Asbestosi ,Middle Aged ,peritoneum ,030210 environmental & occupational health ,Asbestos cement ,Occupational Diseases ,pleura ,Italy ,030220 oncology & carcinogenesis ,malignant mesothelioma ,Female ,Public Health ,Peritoneal Neoplasm ,FIBERS ,Carcinogen ,Cohort study ,Human ,Adult ,medicine.medical_specialty ,Pleural Neoplasms ,MODELS ,Socio-culturale ,Asbesto ,Asbestos ,Settore MED/01 - Statistica Medica ,CEMENT WORKERS ,03 medical and health sciences ,LUNG-CANCER ,asbestos ,occupational cancer ,ovary ,Internal medicine ,Occupational Exposure ,medicine ,Humans ,METAANALYSIS ,Aged ,LARYNGEAL-CANCER-MORTALITY, PLEURAL MESOTHELIOMA, TEXTILE WORKERS, LUNG-CANCER, FOLLOW-UP, CEMENT WORKERS,MODELS ,RISK, METAANALYSIS, FIBERS ,business.industry ,Construction Materials ,Ovarian Neoplasm ,Environmental and Occupational Health ,Mesothelioma, Malignant ,Ovary ,Public Health, Environmental and Occupational Health ,Ambientale ,medicine.disease ,Surgery ,Construction Material ,Lung Neoplasm ,Occupational Disease ,Carcinogens ,Cohort Studie ,FOLLOW-UP ,Ovarian cancer ,business - Abstract
Objective Asbestos is a known human carcinogen, with evidence for malignant mesothelioma (MM), cancers of lung, ovary, larynx and possibly other organs. MM rates are predicted to increase with a power of time since first exposure (TSFE), but the possible long-term attenuation of the trend is debated. The asbestos ban enforced in Italy in 1992 gives an opportunity to measure long-term cancer risk in formerly exposed workers. Methods Pool of 43 previously studied Italian asbestos cohorts (asbestos cement, rolling stock, shipbuilding), with mortality follow-up updated to 2010. SMRs were computed for the 1970–2010 period, for the major causes, with consideration of duration and TSFE, using reference rates by age, sex, region and calendar period. Results The study included 51 801 subjects (5741 women): 55.9% alive, 42.6% died (cause known for 95%) and 1.5% lost to follow-up. Mortality was significantly increased for all deaths (SMR: men: 1.05, 95% CI 1.03 to 1.06; women: 1.17, 95% CI to 1.12 to 1.22), all malignancies combined (SMR: men: 1.17, 95% CI to 1.14 to 1.20; women: 1.33, 95% CI 1.24 to 1.43), pleural and peritoneal malignancies (SMR: men: 13.28 and 4.77, 95% CI 12.24 to 14.37 and 4.00 to 5.64; women: 28.44 and 6.75, 95% CI 23.83 to 33.69 and 4.70 to 9.39), lung (SMR: men: 1.26, 95% CI 1.21 to 1.31; women: 1.43, 95% CI 1.13 to 1.78) and ovarian cancer (SMR=1.38, 95% CI 1.00 to 1.87) and asbestosis (SMR: men: 300.7, 95% CI 270.7 to 333.2; women: 389.6, 95% CI 290.1 to 512.3). Pleural cancer rate increased during the first 40 years of TSFE and reached a plateau after. Discussion The study confirmed the increased risk for cancer of the lung, ovary, pleura and peritoneum but not of the larynx and the digestive tract. Pleural cancer mortality reached a plateau at long TSFE, coherently with recent reports.
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- 2017
14. Italian pool of asbestos workers cohorts: asbestos related mortality by industrial sector and cumulative exposure.
- Author
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Magnani C, Silvestri S, Angelini A, Ranucci A, Azzolina D, Cena T, Chellini E, Merler E, Pavone V, Miligi L, Gorini G, Bressan V, Girardi P, Bauleo L, Romeo E, Luberto F, Sala O, Scarnato C, Menegozzo S, Oddone E, Tunesi S, Perticaroli P, Pettinari A, Cuccaro F, Mattioli S, Baldassarre A, Barone-Adesi F, Musti M, Mirabelli D, Pirastu R, Marinaccio A, Massari S, and Ferrante D
- Subjects
- Cause of Death, Cohort Studies, Female, Humans, Italy epidemiology, Lung Neoplasms etiology, Lung Neoplasms mortality, Mineral Fibers toxicity, Ovarian Neoplasms etiology, Ovarian Neoplasms mortality, Peritoneal Neoplasms etiology, Peritoneal Neoplasms mortality, Pleural Neoplasms etiology, Pleural Neoplasms mortality, Retrospective Studies, Risk, Urinary Bladder Neoplasms etiology, Urinary Bladder Neoplasms mortality, Asbestos toxicity, Asbestosis mortality, Construction Materials toxicity, Industry, Occupational Exposure adverse effects
- Abstract
Objective: Italy has been a large user of asbestos and asbestos containing materials until the 1992 ban. We present a pooled cohort study on long-term mortality in exposed workers., Methods: Pool of 43 Italian asbestos cohorts (asbestos cement, rolling stock, shipbuilding, glasswork, harbors, insulation and other industries). SMRs were computed by industrial sector for the 1970-2010 period, for the major causes, using reference rates by age, sex, region and calendar period., Results: The study included 51 801 subjects (5741 women): 55.9% alive, 42.6% died (cause known for 95%) and 1.5% lost to follow-up. Asbestos exposure was estimated at the plant and period levels. Asbestos related mortality was significantly increased. All industrial sectors showed increased mortality from pleural malignancies, and most also from peritoneal and lung cancer and asbestosis, with exposure related trend. Increased mortality was also observed for ovarian cancer and for bladder cancer., Discussion: The study confirmed the increased risk for cancer of the lung, ovary, pleura and peritoneum but not of the larynx and the digestive tract. A large increase in mortality from asbestosis was observed.
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- 2020
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15. [Time trend in mesothelioma and lung cancer risk in asbestos workers in Italy].
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Magnani C, Ancona L, Baldassarre A, Bressan V, Cena T, Chellini E, Cuccaro F, Ferrante D, Legittimo P, Luberto F, Marinaccio A, Mattioli S, Menegozzo S, Merler E, Miligi L, Mirabelli D, Musti M, Oddone E, Pavone V, Perticaroli P, Pettinari A, Pirastu R, Ranucci A, Romeo E, Sala O, Scarnato C, and Silvestri S
- Subjects
- Asbestos, Asbestosis, Female, Humans, Italy epidemiology, Male, Occupational Diseases, Lung Neoplasms epidemiology, Mesothelioma epidemiology, Occupational Exposure
- Abstract
This study aims at investigating, in asbestos exposed workers, the time trend of their risk of mesothelioma and of other neoplasm after very long latency and after the cessation of asbestos exposure. We pooled a large number of Italian cohorts of asbestos workers and updated mortality follow-up. The pool of data for statistical analyses includes 51,988 workers, of which 6,058 women: 54.2% was alive at follow-up, 42.6% was dead, and 2.8%was lost. Cause of death is known for 94.3%: 2,548 deaths from lung cancer, 748 frompleural cancer, 173 fromperitoneal cancer, and 434 from asbestosis. An exposure index is being developed to compare the different cohorts. Data analysis is in progress. This study will have the size for analysing not only time trends in mesothelioma, but also the occurrence of rarer diseases and cancer specific mortality in women.
- Published
- 2016
- Full Text
- View/download PDF
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