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11. Pancreatic Cancer

Author

Pflüger, Michael J., primary, Noë, Michaël, additional, and Brosens, Lodewijk A.A., additional

Published
2023
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12. The Impact of Clinical and Pathological Features on Intraductal Papillary Mucinous Neoplasm Recurrence After Surgical Resection: Long-Term Follow-Up Analysis

Author

Pflüger, Michael J., Griffin, James F., Hackeng, Wenzel M., Kawamoto, Satomi, Yu, Jun, Chianchiano, Peter, Shin, Eunice, Lionheart, Gemma, Tsai, Hua-Ling, Wang, Hao, Rezaee, Neda, Burkhart, Richard A., Cameron, John L., Thompson, Elizabeth D., Wolfgang, Christopher L., He, Jin, Brosens, Lodewijk A. A., and Wood, Laura D.

Published
2020
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16. Supplementary Video 8 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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17. Supplementary Table 1 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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18. Supplementary Methods from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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19. Supplementary Video 6 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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20. Data from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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21. Supplementary Video 3 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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22. Supplementary Video 2 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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23. Supplementary Table 3 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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24. Supplementary Video 7 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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25. Supplementary Video 5 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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26. Supplementary Figure 5 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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27. Supplementary Figure 6 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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28. Supplementary Figure 3 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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29. Supplementary Figure 4 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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30. Supplementary Figure 1 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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31. Supplementary Table 4 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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32. Supplementary Video 1 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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33. Supplementary Table 2 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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34. Supplementary Video 4 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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35. Supplementary Figure 2 from Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome

Author

Huang, Wenjie, primary, Navarro-Serer, Bernat, primary, Jeong, Yea Ji, primary, Chianchiano, Peter, primary, Xia, Limin, primary, Luchini, Claudio, primary, Veronese, Nicola, primary, Dowiak, Cameron, primary, Ng, Tammy, primary, Trujillo, Maria A., primary, Huang, Bo, primary, Pflüger, Michael J., primary, Macgregor-Das, Anne M., primary, Lionheart, Gemma, primary, Jones, Danielle, primary, Fujikura, Kohei, primary, Nguyen-Ngoc, Kim-Vy, primary, Neumann, Neil M., primary, Groot, Vincent P., primary, Hasanain, Alina, primary, van Oosten, A. Floortje, primary, Fischer, Sandra E., primary, Gallinger, Steven, primary, Singhi, Aatur D., primary, Zureikat, Amer H., primary, Brand, Randall E., primary, Gaida, Matthias M., primary, Heinrich, Stefan, primary, Burkhart, Richard A., primary, He, Jin, primary, Wolfgang, Christopher L., primary, Goggins, Michael G., primary, Thompson, Elizabeth D., primary, Roberts, Nicholas J., primary, Ewald, Andrew J., primary, and Wood, Laura D., primary

Published
2023
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36. Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas

Author

Felsenstein, Matthäus, Trujillo, Maria A., Huang, Bo, Nanda, Neha, Jiang, Zhengdong, Jeong, Yea Ji, Pflüger, Michael, Goggins, Michael G., Hruban, Ralph H., Thompson, Elizabeth D., Heaphy, Christopher M., Roberts, Nicholas J., and Wood, Laura D.

Abstract

Intraductal tubulopapillary neoplasm (ITPN) is a distinct precancerous lesion in the pancreas with unique clinical and molecular features. Although in vitro studies in two-dimensional culture have led to numerous important insights in pancreatic cancer, such models are currently lacking for precancerous lesions. In this study, we report the generation and characterization of a cell line from a human pancreatic ITPN. Neoplastic cells were initially cultured in a three-dimensional organoid system, followed by transfer to two-dimensional culture. RNA sequencing revealed a gene expression profile consistent with pancreatic ductal origin, and whole genome sequencing identified many somatic mutations (including in genes involved in DNA repair and Wnt signaling) and structural rearrangements. In vitro characterization of the tumorigenic potential demonstrated a phenotype between that of normal pancreatic ductal cells and cancer cell lines. This cell line represents a valuable resource for interrogation of unique ITPN biology, as well as precancerous pancreatic lesions more generally.

Published
2024
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39. The Worth of Cities in Germany

Author

Gehr, Katja and Pflüger, Michael P.

Subjects
city systems, urban growth, C52, ddc:330, agglomeration and dispersion economies, D24, land-use regulations, R12
Abstract

This paper extends the urban growth model of Duranton and Puga (2022) to explore the impact of cities on local firms and households and the aggregate economy of Germany. We adopt alternative micro-foundations for agglomeration economies and a non-linear specification of human capital accumulation. This allows us to characterize the social optimum and to bring the model in line with semi-endogenous growth. We also innovate by incorporating consumptive amenities and fiscal transfers into the model. On the empirical side we exploit the structural equations of the model and rich sets of micro-data for Germany's labor markets, housing rents, and household travel-to-work data, to estimate the population elasticities of urban benefits and costs. We are the first to establish elasticities for urban costs for Germany, an estimated elasticity of commuting costs with respect to distance travelled of 0.071, and an estimate for the population elasticity of travel congestion of 0.068. Our estimates for static and dynamic agglomeration elasticities are 0.017 and 0.020, respectively. We innovate on the calibration strategy to capture the important role of consumptive amenities and fiscal transfers in Germany. The model innovations and calibration are shown to be strongly supported by several pieces of evidence. Our key policy counterfactual is a proportionate increase of the population in Germany's Top Seven metropolises by 10% which implies a significant overall welfare benefit of 1.12% per person. This involves mild losses for city incumbents but strong gains for city newcomers. We also address the effects of a counter-factual shift to the social optimum and a counterfactual removal of fiscal transfers. Our final exercise evaluates the implications of cities and agglomeration economies for aggregate growth in Germany. We find that these account for 0.011 additional percentage points of growth in income per capita per year.

Published
2023

50. Blood transfusion is associated with worse outcomes following pancreatic resection for pancreatic adenocarcinoma

Author

Javed, Ammar A., primary, Ronnekleiv-Kelly, Sean M., additional, Hasanain, Alina, additional, Pflüger, Michael J., additional, Habib, Joseph R., additional, Wright, Michael J., additional, He, Jin, additional, Cameron, John L., additional, Wolfgang, Christopher L., additional, Frank, Steven M., additional, Weiss, Matthew J., additional, and Burkhart, Richard A., additional

Published
2022
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