280 results on '"Pfuhler, Stefan"'
Search Results
2. In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data
3. Measuring DNA modifications with the comet assay: a compendium of protocols
4. A weight of evidence review of the genotoxicity of titanium dioxide (TiO2)
5. Within‐laboratory reproducibility of Ames test results: Are repeat tests necessary?
6. Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment
7. Toxins in Botanical Drugs and Plant-derived Food and Feed – from Science to Regulation: A Workshop Review
8. Pyrrolizidine alkaloids in food and phytomedicine: Occurrence, exposure, toxicity, mechanisms, and risk assessment - A review
9. Toxins in Botanical Drugs and Plant-derived Food and Feed – from Science to Regulation: A Workshop Review
10. Interpretation of In Vitro Concentration‐Response Data for Risk Assessment and Regulatory Decision‐making: Report from the 2022 IWGT Quantitative Analysis Expert Working Group Meeting
11. The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
12. 3D Skin Comet Assay
13. Reconstructed Skin Micronucleus Assay (RSMN)
14. Overview on Current Status
15. Role in a Testing Strategy
16. Relative potency of fifteen pyrrolizidine alkaloids to induce DNA damage as measured by micronucleus induction in HepaRG human liver cells
17. Measuring DNA modifications with the comet assay:a compendium of protocols
18. Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose
19. Quantitative in vitro to in vivo Extrapolation (IVIVE) of Genotoxicity Data Provides Protective Estimates of in vivo Dose
20. The in vitro genotoxicity potency of mixtures of pyrrolizidine alkaloids can be explained by dose addition of the individual mixture components
21. Assessing the genotoxicity and carcinogenicity of 2-chloroethanol through structure activity relationships and in vitro testing approaches
22. Re: Gi et al. 2018, In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats, Archives of Toxicology 92:3207–3221
23. Adverse Outcome Pathway on Oxidative DNA damage leading to chromosomal aberrations and mutations.
24. AOP Report: Development of an Adverse Outcome Pathway for Oxidative DNA Damage Leading to Mutations and Chromosomal Aberrations
25. Weak silica nanomaterial-induced genotoxicity can be explained by indirect DNA damage as shown by the OGG1-modified comet assay and genomic analysis
26. Utility of ToxTracker in animal alternative testing strategy for fragrance materials.
27. Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not
28. Correction to: Re: Gi et al. 2018, In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats, Archives of Toxicology 92:3207–3221
29. Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type
30. In vivo Mammalian Alkaline Comet Assay: Method Adapted for Genotoxicity Assessment of Nanomaterials
31. Common Considerations for Genotoxicity Assessment of Nanomaterials
32. AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations
33. In vivo Mammalian Alkaline Comet Assay: Method Adapted for Genotoxicity Assessment of Nanomaterials
34. In vitro genotoxicity test approaches with better predictivity: Summary of an IWGT workshop
35. The reconstructed skin micronucleus assay (RSMN) in EpiDerm™: Detailed protocol and harmonized scoring atlas
36. The BlueScreen HC assay to predict the genotoxic potential of fragrance materials
37. Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose.
38. A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis
39. Use of the EpiDermTM 3D reconstructed skin micronucleus assay for fragrance materials
40. Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–A Workshop Report
41. A genotoxicity assessment approach for botanical materials demonstrated with Poria cocos
42. In vitro and integrated in vivo strategies to reduce animal use in genotoxicity testing
43. Opportunities to integrate new approaches in genetic toxicology: An ILSI-HESI workshop report
44. Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities—Report from an ECVAM workshop
45. Emerging approaches in predictive toxicology
46. Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
47. N-acetylation of three aromatic amine hair dye precursor molecules eliminates their genotoxic potential
48. The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation
49. Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7 International Workshop on Genotoxicity Testing (IWGT)
50. Risk governance of emerging technologies demonstrated in terms of its applicability to nanomaterials
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