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5. contributors

Author

AbdelFattah, Kareem R., primary, Aboutanos, Michel B., additional, Aliperti, Louis A., additional, Anderson, John T., additional, Anjaria, Devashish J., additional, Asensio, Juan A., additional, Askari, Morad, additional, Bailey, Jeffrey A., additional, Balters, Marcus, additional, Barbosa, Ron, additional, Barie, Philip S., additional, Bedrick, Edward J., additional, Berne, John D., additional, Berry, Stepheny D., additional, Bertelotti, Robert, additional, Bhatia, Pulkesh, additional, Biffl, Walter L., additional, Biggerstaff, Brian, additional, Bini, John K., additional, Blaisdell, F. William, additional, Bozeman, Matthew C., additional, Brandes, Steven B., additional, Brasel, Karen J., additional, Braslow, Benjamin M., additional, Britt, L.D., additional, Brundage, Susan I., additional, Brush, Thomas P., additional, Burlew, Clay Cothren, additional, Marie Byers, Patricia, additional, Caban, Kim M., additional, Cannon, Jeremy, additional, Cantie, Shawn M., additional, Esparragon, José Ceballos, additional, Champion, Howard R., additional, Chandler, Benjamin, additional, Chang, David C., additional, Cheung, Steven, additional, Chiu, William C., additional, Christmas, A. Britton, additional, Ciesla, David J., additional, Cioffi, William G., additional, Cocanour, Christine S., additional, Cohen, Mitchell J., additional, Coimbra, Raul, additional, Collister, Peter, additional, Cornwell, Edward E., additional, Cox, Thomas B., additional, Croce, Martin A., additional, Danton, Gary H., additional, Davis, Kimberly A., additional, Degiannis, Elias, additional, Deitch, Edwin A., additional, Denney, Richard, additional, Dente, Christopher J., additional, Desai, Urmen, additional, Dicker, Rochelle A., additional, Diebel, Lawrence N., additional, Dimitryi, Karev, additional, Doben, Andrew R., additional, Doucet, Jay, additional, Duane, Therese M., additional, DuBose, Joe, additional, Dubov, Wayne, additional, Duchesne, Juan C., additional, Dudrick, Stanley J., additional, Durham, Rodney, additional, Durso, Anthony M., additional, Eachempati, Soumitra R., additional, Eastridge, Colonel (Ret.) Brian, additional, Ebadat, Aileen, additional, Efron, David T., additional, Elster, Eric, additional, Englehart, Michael, additional, Esposito, Thomas J., additional, Estebanez, Glyn, additional, Evans, Susan, additional, Fakhry, Samir M., additional, Falvo, Anthony, additional, Feliciano, David V., additional, Fernández, Luis G., additional, Fink, Mitchell, additional, Flint, Lewis M., additional, Fry, Donald E., additional, Fujita, Takashi, additional, Galante, Joseph M., additional, Gamelli, Richard L., additional, García-Núñez, Luis Manuel, additional, Gentilello, Larry M., additional, Gilani, Ramyar, additional, Glance, Laurent G., additional, Gonzalez, Nestor R., additional, Grabo, Daniel J., additional, Gracia, Gerald J., additional, Gracias, Vincente H., additional, Gross, Kirby R., additional, Gross, Ronald I., additional, Guidry, Chrissy, additional, Gunter, Oliver L., additional, Gutmann, Joseph M., additional, Hale, Erin, additional, Hameed, S. Morad, additional, Hartmann, Molly, additional, Hauser, Carl, additional, Henry, Sharon, additional, Horst, Mathilda, additional, Hoschander, Ari, additional, Houin, Herman P., additional, Hoyt, David, additional, Huston, Jared M., additional, Ipaktchi, Kyros, additional, Joseph, D’Andrea, additional, Jurkovich, Gregory J., additional, Kalandiak, Steven, additional, Karmy-Jones, Riyad, additional, Khoo, Larry T., additional, Kiraly, Laszlo, additional, Kirton, Orlando C., additional, Ksycki, Michael, additional, Kunac, Anastasia, additional, Laeeq, Kulsoom, additional, Ledgerwood, Anna M., additional, Lemelman, Benjamin T., additional, Leppäniemi, Ari, additional, Livingston, David H., additional, Loden, Jason, additional, Lombardo, Gary, additional, Loukas, Andrew, additional, Lucas, Charles E., additional, Luchette, Fred A., additional, Mabry, Charles D., additional, Mackersie, Robert C., additional, Maggio, Paul M., additional, Magnotti, Louis J., additional, Mah, John W., additional, Malhotra, Ajai K., additional, Malinoski, Darren, additional, Maloley-Lewis, Brittney J., additional, Marini, Corrado Paolo, additional, Martin, Colonel Matthew J., additional, Mason, Leonard, additional, Mattox, Kenneth L., additional, Maull, Kimball, additional, Mayberry, John C., additional, Mazzini, Federico N., additional, McFarren, Christopher, additional, McSwain, Norman E., additional, Meallet, Mario A., additional, Meredith, J. Wayne, additional, Michetti, Christopher P., additional, Miller, Keith R., additional, Miller, Preston R., additional, Miller, Richard S., additional, Minei, Joseph P., additional, Mir, Haaris, additional, Mitchell, Frank L., additional, Mohr, Alicia M., additional, Moore, Ernest E., additional, Mosenthal, Anne C., additional, Munera, Felipa, additional, Murdock, Alan D., additional, Nabri, Mamoun, additional, Napolitano, Lena M., additional, Nash, Nicholas A., additional, Norwood, Scott H., additional, Oeltjen, John, additional, Okwuosa, Chris, additional, Osler, Turner M., additional, Osmolak, Angela, additional, Otomo, Yasuhiro, additional, Owens, Patrick, additional, Owings, John T., additional, Pachter, H. Leon, additional, Palange, David, additional, Panthaki, Zubin Jal, additional, Parikh, Manish S., additional, Pasquale, Michael D., additional, Peitzman, Andrew B., additional, Perez-Alonso, Alejandro, additional, Perkins, Christopher H., additional, Person, Austin, additional, Petrone, Patrizio, additional, Pharaon, K. Shad, additional, Philp, Allan S., additional, Pierre, Edgar J., additional, Piper, Greta L., additional, Plani, Frank, additional, Polanco, Patricio, additional, Policastro, Anthony, additional, Powell, Nathan J., additional, Pretorius, Riaan, additional, Propper, Brandon, additional, Pust, G. Daniel, additional, Putty, Bradley S., additional, Puyana, Juan Carlos, additional, Quinnan, Stephen M., additional, Quintana, David J., additional, Reed, R. Lawrence, additional, Reiser, Bibiana J., additional, Rhee, Peter, additional, Rhodes, Michael, additional, Rich, Norman M., additional, Richardson, J. David, additional, Richart, Charles M., additional, Rivas, Luis A., additional, Roberts, Jennifer C., additional, Rodríguez, Aurelio, additional, Rodríguez, Jorge L., additional, Rodriguez-García, Erwin, additional, Roeder, Rosaine, additional, Rojas-Tirado, David, additional, Rotondo, Michael F., additional, Rowell, Susan, additional, Rubano, Jerry A., additional, Rubiano, Andrés M., additional, Rushing, Amy, additional, Sade, Irony C., additional, Salgado, Christopher, additional, Salim, Ali, additional, Salliant, Noelle, additional, Salsamendi, Jason, additional, Sampson, James B., additional, Sanchez, Juan A., additional, Sánchez Maldonado, William, additional, Scalea, Thomas M., additional, Schecter, William P., additional, Schipper, Paul, additional, Schreiber, Martin, additional, Schulz, John T., additional, Schwab, C. William, additional, Serio, Stephen, additional, Shah, Parth, additional, Shapiro, Marc J., additional, Shatz, David, additional, Shetty, Shreya, additional, Shiroff, Adam M., additional, Sifri, Ziad C., additional, Sing, Ronald, additional, Sisley, Amy C., additional, Smith, R. Stephen, additional, Smith-Singares, Eduardo, additional, Spain, David A., additional, Spoerke, Nicholas, additional, Srinivasan, Ananth, additional, Stein, Deborah M., additional, Stirparo, Joseph J., additional, Stuke, Lance E., additional, Sukumar, Mithran, additional, Sundaram, Abhishek, additional, Svetanoff, Wendy Jo, additional, Swan, Kenneth G., additional, Tashjian, Vartan S., additional, Templin, Thomas, additional, Thal, Erwin, additional, Thaller, Seth R., additional, Tiesi, Gregory, additional, Tieu, Brandon, additional, Tillou, Areti, additional, Tinkoff, Glen, additional, Tisherman, Samuel, additional, Todd, S. Rob, additional, Torgersen, Zachary, additional, Trafton, Peter G., additional, Traynham, Mark, additional, Scherer, L.R. Tres, additional, Trunkey, Donald D., additional, Tsai, Peter I., additional, Tuggle, David W., additional, Udekwu, Anthony M., additional, Valadka, Alex B., additional, VanDerHeyden, Nicole, additional, Varghese, Thomas K., additional, Wagner, Michel, additional, Wall, Matthew J., additional, Watkins, Anthony, additional, Weigelt, John, additional, Weireter, Leonard J., additional, Welling, David R., additional, White, Paul W., additional, Wiegand, Lucas R., additional, Wilkins, Harry E., additional, Wilson, Robert F., additional, Wisner, David H., additional, and Yeh, D. Dante, additional

Published
2016
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9. Targeted Temperature Management for Traumatic Arrest

Author

Cragun, Benjamin, primary, Philp, Frances Hite, additional, Tindall, Rachel P., additional, O'Neill, John, additional, Bell, Nathan, additional, Noorbakhsh, Matthew, additional, Philp, Allan S., additional, and Ditillo, Michael F., additional

Published
2017
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11. 32

Author

Rittenhouse-pukah, Jennifer, primary, Philp, Frances, additional, Philp, Allan, additional, and Toevs, Christine, additional

Published
2013
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12. 742

Author

Philp, Allan, primary, Vosburg, R, additional, and Ong, Adrian, additional

Published
2013
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13. contributors

Author

AbdelFattah, Kareem R., Aboutanos, Michel B., Aliperti, Louis A., Anderson, John T., Anjaria, Devashish J., Asensio, Juan A., Askari, Morad, Bailey, Jeffrey A., Balters, Marcus, Barbosa, Ron, Barie, Philip S., Bedrick, Edward J., Berne, John D., Berry, Stepheny D., Bertelotti, Robert, Bhatia, Pulkesh, Biffl, Walter L., Biggerstaff, Brian, Bini, John K., Blaisdell, F. William, Bozeman, Matthew C., Brandes, Steven B., Brasel, Karen J., Braslow, Benjamin M., Britt, L.D., Brundage, Susan I., Brush, Thomas P., Burlew, Clay Cothren, Marie Byers, Patricia, Caban, Kim M., Cannon, Jeremy, Cantie, Shawn M., Esparragon, José Ceballos, Champion, Howard R., Chandler, Benjamin, Chang, David C., Cheung, Steven, Chiu, William C., Christmas, A. Britton, Ciesla, David J., Cioffi, William G., Cocanour, Christine S., Cohen, Mitchell J., Coimbra, Raul, Collister, Peter, Cornwell, Edward E., III, Cox, Thomas B., Croce, Martin A., Danton, Gary H., Davis, Kimberly A., Degiannis, Elias, Deitch, Edwin A., Denney, Richard, Dente, Christopher J., Desai, Urmen, Dicker, Rochelle A., Diebel, Lawrence N., Dimitryi, Karev, Doben, Andrew R., Doucet, Jay, Duane, Therese M., DuBose, Joe, Dubov, Wayne, Duchesne, Juan C., Dudrick, Stanley J., Durham, Rodney, Durso, Anthony M., Eachempati, Soumitra R., Eastridge, Colonel (Ret.) Brian, Ebadat, Aileen, Efron, David T., Elster, Eric, Englehart, Michael, Esposito, Thomas J., Estebanez, Glyn, Evans, Susan, Fakhry, Samir M., Falvo, Anthony, Feliciano, David V., Fernández, Luis G., Fink, Mitchell, Flint, Lewis M., Fry, Donald E., Fujita, Takashi, Galante, Joseph M., Gamelli, Richard L., García-Núñez, Luis Manuel, Gentilello, Larry M., Gilani, Ramyar, Glance, Laurent G., Gonzalez, Nestor R., Grabo, Daniel J., Gracia, Gerald J., Gracias, Vincente H., Gross, Kirby R., Gross, Ronald I., Guidry, Chrissy, Gunter, Oliver L., Jr., Gutmann, Joseph M., Hale, Erin, Hameed, S. Morad, Hartmann, Molly, Hauser, Carl, Henry, Sharon, Horst, Mathilda, Hoschander, Ari, Houin, Herman P., Hoyt, David, Huston, Jared M., Ipaktchi, Kyros, Joseph, D’Andrea, Jurkovich, Gregory J., Kalandiak, Steven, Karmy-Jones, Riyad, Khoo, Larry T., Kiraly, Laszlo, Kirton, Orlando C., Ksycki, Michael, Kunac, Anastasia, Laeeq, Kulsoom, Ledgerwood, Anna M., Lemelman, Benjamin T., Leppäniemi, Ari, Livingston, David H., Loden, Jason, Lombardo, Gary, Loukas, Andrew, Lucas, Charles E., Luchette, Fred A., Mabry, Charles D., Mackersie, Robert C., Maggio, Paul M., Magnotti, Louis J., Mah, John W., Malhotra, Ajai K., Malinoski, Darren, Maloley-Lewis, Brittney J., Marini, Corrado Paolo, Martin, Colonel Matthew J., Mason, Leonard, Mattox, Kenneth L., Maull, Kimball, Mayberry, John C., Mazzini, Federico N., Dr., McFarren, Christopher, McSwain, Norman E., Jr., Meallet, Mario A., Meredith, J. Wayne, Michetti, Christopher P., Miller, Keith R., Miller, Preston R., Miller, Richard S., Minei, Joseph P., Mir, Haaris, Mitchell, Frank L., Mohr, Alicia M., Moore, Ernest E., Mosenthal, Anne C., Munera, Felipa, Murdock, Alan D., Nabri, Mamoun, Napolitano, Lena M., Nash, Nicholas A., Norwood, Scott H., Oeltjen, John, Okwuosa, Chris, Osler, Turner M., Osmolak, Angela, Otomo, Yasuhiro, Owens, Patrick, Owings, John T., Pachter, H. Leon, Palange, David, Panthaki, Zubin Jal, Parikh, Manish S., Pasquale, Michael D., Peitzman, Andrew B., Perez-Alonso, Alejandro, Perkins, Christopher H., Person, Austin, Petrone, Patrizio, Pharaon, K. Shad, Philp, Allan S., Pierre, Edgar J., Piper, Greta L., Plani, Frank, Polanco, Patricio, Policastro, Anthony, Powell, Nathan J., Pretorius, Riaan, Propper, Brandon, Pust, G. Daniel, Putty, Bradley S., Puyana, Juan Carlos, Quinnan, Stephen M., Quintana, David J., Reed, R. Lawrence, II, Reiser, Bibiana J., Rhee, Peter, Rhodes, Michael, Rich, Norman M., Richardson, J. David, Richart, Charles M., Rivas, Luis A., Roberts, Jennifer C., Rodríguez, Aurelio, Rodríguez, Jorge L., Rodriguez-García, Erwin, Roeder, Rosaine, Rojas-Tirado, David, Rotondo, Michael F., Rowell, Susan, Rubano, Jerry A., Rubiano, Andrés M., Rushing, Amy, Sade, Irony C., Salgado, Christopher, Salim, Ali, Salliant, Noelle, Salsamendi, Jason, Sampson, James B., Sanchez, Juan A., Sánchez Maldonado, William, Scalea, Thomas M., Schecter, William P., Schipper, Paul, Schreiber, Martin, Schulz, John T., III, Schwab, C. William, Serio, Stephen, Shah, Parth, Shapiro, Marc J., Shatz, David, Shetty, Shreya, Shiroff, Adam M., Sifri, Ziad C., Sing, Ronald, Sisley, Amy C., Smith, R. Stephen, Smith-Singares, Eduardo, Spain, David A., Spoerke, Nicholas, Srinivasan, Ananth, Stein, Deborah M., Stirparo, Joseph J., Stuke, Lance E., Sukumar, Mithran, Sundaram, Abhishek, Svetanoff, Wendy Jo, Swan, Kenneth G., Tashjian, Vartan S., Templin, Thomas, Thal, Erwin, Thaller, Seth R., Tiesi, Gregory, Tieu, Brandon, Tillou, Areti, Tinkoff, Glen, Tisherman, Samuel, Todd, S. Rob, Torgersen, Zachary, Trafton, Peter G., Traynham, Mark, Scherer, L.R. Tres, Trunkey, Donald D., Tsai, Peter I., Tuggle, David W., Udekwu, Anthony M., Valadka, Alex B., VanDerHeyden, Nicole, Varghese, Thomas K., Jr., Wagner, Michel, Wall, Matthew J., Jr., Watkins, Anthony, Weigelt, John, Weireter, Leonard J., Jr., Welling, David R., White, Paul W., Wiegand, Lucas R., Wilkins, Harry E., Wilson, Robert F., Wisner, David H., and Yeh, D. Dante

Published
2016
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15. 229

Author

Lee, Victoria, primary, Philp, Frances, additional, Chappel, Deborah, additional, and Philp, Allan, additional

Published
2012
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16. 643

Author

Rittenhouse-pukah, Jennifer, primary, Philp, Frances, additional, Yenugadhati, Vamsi, additional, Philp, Allan, additional, Jeremitsky, Elan, additional, and Toevs, Christine, additional

Published
2012
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19. Teamwork Training Improves the Clinical Care of Trauma Patients

Author

Capella, Jeannette, primary, Smith, Stephen, additional, Philp, Allan, additional, Putnam, Tyler, additional, Gilbert, Carol, additional, Fry, William, additional, Harvey, Ellen, additional, Wright, Andi, additional, Henderson, Krista, additional, Baker, David, additional, Ranson, Sonya, additional, and ReMine, Stephen, additional

Published
2010
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21. An Evaluation of Multidetector Computed Tomography in Detecting Pancreatic Injury: Results of a Multicenter AAST Study

Author

Phelan, Herb A., primary, Velmahos, George C., additional, Jurkovich, Gregory J., additional, Friese, Randall S., additional, Minei, Joseph P., additional, Menaker, Jay A., additional, Philp, Allan, additional, Evans, Heather L., additional, Gunn, Martin L., additional, Eastman, Alexander L., additional, Rowell, Susan E., additional, Allison, Carrie E., additional, Barbosa, Ronald L., additional, Norwood, Scott H., additional, Tabbara, Malek, additional, Dente, Christopher J., additional, Carrick, Matthew M., additional, Wall, Matthew J., additional, Feeney, Jim, additional, O’Neill, Patrick J., additional, Srinivas, Gujjarappa, additional, Brown, Carlos V. R., additional, Reifsnyder, Andrew C., additional, Hassan, Moustafa O., additional, Albert, Scott, additional, Pascual, Jose L., additional, Strong, Michelle, additional, Moore, Forrest O., additional, Spain, David A., additional, Purtill, Mary-Anne, additional, Edwards, Byard, additional, Strauss, Jason, additional, Durham, Rodney M., additional, Duchesne, Juan C., additional, Greiffenstein, Patrick, additional, and Cothren, C Clay, additional

Published
2009
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23. Administration of andexanet alfa for traumatic intracranial hemorrhage in the setting of massive apixaban overdose: A case report.

Author

Jenniches, Daniel, Kerns, Abigail F, DelBianco, John, Stripp, Matthew P, and Philp, Allan S

Subjects
*HOSPITAL emergency services, *INTRACRANIAL hemorrhage, *DRUG overdose, *ATORVASTATIN, *ANTICOAGULANTS, *COMMUNITY health services, *THROMBELASTOGRAPHY, *MAGNETIC resonance imaging, *ADRENERGIC beta blockers, *CARVEDILOL, *ACCIDENTAL falls, *WOUNDS & injuries
Abstract

Purpose Apixaban is a direct-acting oral anticoagulant that selectively inhibits factor Xa. Reversal strategies utilized to treat factor Xa inhibitor–associated bleeding include andexanet alfa, prothrombin complex -concentrate (PCC), and activated PCC (aPCC). The optimal treatment of traumatic intracranial hemorrhage in the setting of an apixaban overdose is unknown. Summary This case report describes a 69-year-old female who initially presented to an emergency department at a community hospital due to a ground-level fall with traumatic intracranial hemorrhage. The patient reportedly ingested apixaban 275 mg, carvedilol 250 mg, atorvastatin 1,200 mg, and unknown amounts of amlodipine and ethanol. Anti-inhibitor coagulant complex, an aPCC, was administered approximately 3 hours after presentation. Initial thromboelastography performed approximately 4 hours after presentation showed a prolonged reaction time of 16.8 minutes. Ongoing imaging and evidence of coagulopathy prompted repeated aPCC administration to a cumulative dose of approximately 100 U/kg. The patient underwent craniotomy with hematoma evacuation. Postoperative imaging showed expansion of the existing intracranial hemorrhage and new areas of hemorrhage. Andexanet alfa was administered approximately 18 hours after presentation, followed by repeat craniotomy with evacuation of the hematoma. No further expansion of the intracranial hemorrhage was observed, and the reaction time on thromboelastography was normalized at 6.3 minutes. Conclusion This case suggests that andexanet alfa may have a role in the management of traumatic hemorrhage in the setting of an acute massive apixaban overdose. Use of andexanet alfa, PCC, and aPCC in this context requires further research. [ABSTRACT FROM AUTHOR]

Published
2023
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