Search

Fact-checking is extensively studied in the context of misinformation and disinformation, addressing objective inaccuracies. However, a softer form of misinformation involves responses that are factually correct but lack certain features such as clarity and relevance. This challenge is prevalent in formal Question-Answer (QA) settings such as press conferences in finance, politics, sports, and other domains, where subjective answers can obscure transparency. Despite this, there is a lack of manually annotated datasets for subjective features across multiple dimensions. To address this gap, we introduce SubjECTive-QA, a human annotated dataset on Earnings Call Transcripts' (ECTs) QA sessions as the answers given by company representatives are often open to subjective interpretations and scrutiny. The dataset includes 49,446 annotations for long-form QA pairs across six features: Assertive, Cautious, Optimistic, Specific, Clear, and Relevant. These features are carefully selected to encompass the key attributes that reflect the tone of the answers provided during QA sessions across different domain. Our findings are that the best-performing Pre-trained Language Model (PLM), RoBERTa-base, has similar weighted F1 scores to Llama-3-70b-Chat on features with lower subjectivity, such as Relevant and Clear, with a mean difference of 2.17% in their weighted F1 scores. The models perform significantly better on features with higher subjectivity, such as Specific and Assertive, with a mean difference of 10.01% in their weighted F1 scores. Furthermore, testing SubjECTive-QA's generalizability using QAs from White House Press Briefings and Gaggles yields an average weighted F1 score of 65.97% using our best models for each feature, demonstrating broader applicability beyond the financial domain. SubjECTive-QA is publicly available under the CC BY 4.0 license, Comment: Accepted at NeurIPS 2024

Photoplethysmography (PPG) is the most widely used non-invasive technique for monitoring biosignals and cardiovascular health, with applications in both clinical settings and consumer health through wearable devices. Current machine learning models trained on PPG signals are mostly task-specific and lack generalizability. Previous works often used single-device datasets, did not explore out-of-domain generalization, or did not release their models, hindering reproducibility and further research. We introduce PaPaGei, the first open foundation model for PPG signals. PaPaGei is pre-trained on more than 57,000 hours of 20 million unlabeled segments of PPG signals using publicly available datasets exclusively. We evaluate against popular time-series foundation models and other benchmarks on 20 tasks of 10 diverse datasets spanning cardiovascular health, sleep disorders, pregnancy monitoring, and wellbeing assessment. Our architecture incorporates novel representation learning approaches that leverage differences in PPG signal morphology across individuals, enabling it to capture richer representations than traditional contrastive learning methods. Across 20 tasks, PaPaGei improves classification and regression performance by an average of 6.3% and 2.9%, respectively, compared to other competitive time-series foundation models in at least 14 tasks. PaPaGei is more data- and parameter-efficient than other foundation models or methods, as it outperforms 70x larger models. Beyond accuracy, we also investigate robustness against different skin tones, establishing a benchmark for bias evaluations of future models. Notably, PaPaGei can be used out of the box as both a feature extractor and an encoder for other multimodal models, opening up new opportunities for multimodal health monitoring, Comment: Code and models: https://github.com/nokia-bell-labs/papagei-foundation-model

Mental health concerns are prevalent among college students, highlighting the need for effective interventions that promote self-awareness and holistic well-being. MindScape pioneers a novel approach to AI-powered journaling by integrating passively collected behavioral patterns such as conversational engagement, sleep, and location with Large Language Models (LLMs). This integration creates a highly personalized and context-aware journaling experience, enhancing self-awareness and well-being by embedding behavioral intelligence into AI. We present an 8-week exploratory study with 20 college students, demonstrating the MindScape app's efficacy in enhancing positive affect (7%), reducing negative affect (11%), loneliness (6%), and anxiety and depression, with a significant week-over-week decrease in PHQ-4 scores (-0.25 coefficient), alongside improvements in mindfulness (7%) and self-reflection (6%). The study highlights the advantages of contextual AI journaling, with participants particularly appreciating the tailored prompts and insights provided by the MindScape app. Our analysis also includes a comparison of responses to AI-driven contextual versus generic prompts, participant feedback insights, and proposed strategies for leveraging contextual AI journaling to improve well-being on college campuses. By showcasing the potential of contextual AI journaling to support mental health, we provide a foundation for further investigation into the effects of contextual AI journaling on mental health and well-being., Comment: arXiv admin note: text overlap with arXiv:2404.00487

Scientists increasingly recognize the importance of providing rich, standards-adherent metadata to describe their experimental results. Despite the availability of sophisticated tools to assist in the process of data annotation, investigators generally seem to prefer to use spreadsheets when supplying metadata, despite the limitations of spreadsheets in ensuring metadata consistency and compliance with formal specifications. In this paper, we describe an end-to-end approach that supports spreadsheet-based entry of metadata, while ensuring rigorous adherence to community-based metadata standards and providing quality control. Our methods employ several key components, including customizable templates that capture metadata standards and that can inform the spreadsheets that investigators use to author metadata, controlled terminologies and ontologies for defining metadata values that can be accessed directly from a spreadsheet, and an interactive Web-based tool that allows users to rapidly identify and fix errors in their spreadsheet-based metadata. We demonstrate how this approach is being deployed in a biomedical consortium known as HuBMAP to define and collect metadata about a wide range of biological assays.

AI fairness measurements, including tests for equal treatment, often take the form of disaggregated evaluations of AI systems. Such measurements are an important part of Responsible AI operations. These measurements compare system performance across demographic groups or sub-populations and typically require member-level demographic signals such as gender, race, ethnicity, and location. However, sensitive member-level demographic attributes like race and ethnicity can be challenging to obtain and use due to platform choices, legal constraints, and cultural norms. In this paper, we focus on the task of enabling AI fairness measurements on race/ethnicity for \emph{U.S. LinkedIn members} in a privacy-preserving manner. We present the Privacy-Preserving Probabilistic Race/Ethnicity Estimation (PPRE) method for performing this task. PPRE combines the Bayesian Improved Surname Geocoding (BISG) model, a sparse LinkedIn survey sample of self-reported demographics, and privacy-enhancing technologies like secure two-party computation and differential privacy to enable meaningful fairness measurements while preserving member privacy. We provide details of the PPRE method and its privacy guarantees. We then illustrate sample measurement operations. We conclude with a review of open research and engineering challenges for expanding our privacy-preserving fairness measurement capabilities., Comment: Saikrishna Badrinarayanan and Osonde Osoba contributed equally to this work. Updating text to indicate limitations of sample analyses

We use polarization data from SOFIA HAWC+ to investigate the interplay between magnetic fields and stellar feedback in altering gas dynamics within the high-mass star-forming region RCW 36, located in Vela C. This region is of particular interest as it has a bipolar HII region powered by a massive star cluster which may be impacting the surrounding magnetic field. To determine if this is the case, we apply the Histogram of Relative Orientations (HRO) method to quantify the relative alignment between the inferred magnetic field and elongated structures observed in several datasets such as dust emission, column density, temperature, and spectral line intensity maps. The HRO results indicate a bimodal alignment trend, where structures observed with dense gas tracers show a statistically significant preference for perpendicular alignment relative to the magnetic field, while structures probed by photo-dissociation region (PDR) tracers tend to align preferentially parallel relative to the magnetic field. Moreover, the dense gas and PDR associated structures are found to be kinematically distinct such that a bimodal alignment trend is also observed as a function of line-of-sight velocity. This suggests that the magnetic field may have been dynamically important and set a preferred direction of gas flow at the time that RCW 36 formed, resulting in a dense ridge developing perpendicular to the magnetic field. However on filament-scales near the PDR region, feedback may be energetically dominating the magnetic field, warping its geometry and the associated flux-frozen gas structures, causing the observed the preference for parallel relative alignment., Comment: 40 pages (25 pages main paper, 15 pages appendix), 24 figures, 5 tables, accepted for publication in ApJ

This paper explores the pitfalls in evaluating multilingual automatic speech recognition (ASR) models, with a particular focus on Indic language scripts. We investigate the text normalization routine employed by leading ASR models, including OpenAI Whisper, Meta's MMS, Seamless, and Assembly AI's Conformer, and their unintended consequences on performance metrics. Our research reveals that current text normalization practices, while aiming to standardize ASR outputs for fair comparison, by removing inconsistencies such as variations in spelling, punctuation, and special characters, are fundamentally flawed when applied to Indic scripts. Through empirical analysis using text similarity scores and in-depth linguistic examination, we demonstrate that these flaws lead to artificially improved performance metrics for Indic languages. We conclude by proposing a shift towards developing text normalization routines that leverage native linguistic expertise, ensuring more robust and accurate evaluations of multilingual ASR models., Comment: Accepted to EMNLP 2024 Main

Parallel tempering is meta-algorithm for Markov Chain Monte Carlo that uses multiple chains to sample from tempered versions of the target distribution, enhancing mixing in multi-modal distributions that are challenging for traditional methods. The effectiveness of parallel tempering is heavily influenced by the selection of chain temperatures. Here, we present an adaptive temperature selection algorithm that dynamically adjusts temperatures during sampling using a policy gradient approach. Experiments demonstrate that our method can achieve lower integrated autocorrelation times compared to traditional geometrically spaced temperatures and uniform acceptance rate schemes on benchmark distributions., Comment: 11 pages, 5 figures, accepted to ICML 2024 Workshop on Structured Probabilistic Inference & Generative Modeling

We consider equivariant solutions for the Schr\"odinger Map equation in $2+1$ dimensions, with values into $\mathbb{S}^2$. Within each equivariance class $m \in \mathbb{Z}$ this admits a lowest energy nontrivial steady state $Q^m$, which extends to a two dimensional family of steady states by scaling and rotation. If $|m| \geq 3$ then these ground states are known to be stable in the energy space $\dot H^1$, whereas instability and even finite time blow-up along the ground state family may occur if $|m| = 1$. In this article we consider the most delicate case $|m| = 2$. Our main result asserts that small $\dot H^1$ perturbations of the ground state $Q^2$ yield global in time solutions, which satisfy global dispersive bounds. Unlike the higher equivariance classes, here we expect solutions to move arbitrarily far along the soliton family; however, we are able to provide a time dependent bound on the growth of the scale modulation parameter. We also show that within the equivariant class the ground state is stable in a slightly stronger topology $X \subset \dot H^1$., Comment: 146 pages

In this study, we employ molecular simulations to investigate the enhancement in thermal conductance at the solid/liquid interface in the presence of a meniscus reported previously (Klochko et al., Phys. Chem. Chem. Phys. 25(4):3298-3308, 2023). We vary the solid/liquid interaction strength at Lennard-Jones interfaces for both confined liquid and meniscus systems, finding that the presence of a meniscus yields an enhancement in the interfacial thermal conductance across all wettabilities. However, the magnitude of the enhancement is found to depend on the surface wettability, initially rising monotonously for low to moderate wettabilities, followed by a sharp rise between moderate and high wettabilities. The spectral decomposition of heat flux formalism was applied to understand the nature of this phenomenon further. By computing the in-plane and out-of-plane components of the heat fluxes within both the interfacial solid and liquid, we show that the initial monotonous rise in conductance enhancement predominantly stems from a rise in the coupling of out-of-plane vibrations within both the solid and the liquid. In contrast, the subsequent sharp rise at more wetting interfaces is linked to sharp increases in the utilization of the in-plane modes of the solid and liquid. These observations result from the interplay between the solid/liquid adhesive forces and the liquid/vapor interfacial tension. Our results can aid engineers in optimizing thermal transport at realistic interfaces, which is critical to designing effective cooling solutions for electronics, among other applications.

Vibrational spectroscopy is a cornerstone technique for molecular characterization and offers an ideal target for the computational investigation of molecular materials. Building on previous comprehensive assessments of efficient methods for infrared (IR) spectroscopy, this study investigates the predictive accuracy and computational efficiency of gas-phase IR spectra calculations, accessible through a combination of modern semiempirical quantum mechanical and transferable machine learning potentials. A composite approach for IR spectra prediction based on the doubly-harmonic approximation, utilizing harmonic vibrational frequencies in combination squared derivatives of the molecular dipole moment, is employed. This approach allows for methodical flexibility in the calculation of IR intensities from molecular dipoles and the corresponding vibrational modes. Various methods are systematically tested to suggest a suitable protocol with an emphasis on computational efficiency. Among these methods, semiempirical extended tight-binding (xTB) models, classical charge equilibrium models, and machine learning potentials trained for dipole moment prediction are assessed across a diverse dataset of organic molecules. We particularly focus on the recently reported machine learning potential MACE-OFF23 to address the accuracy limitations of conventional low-cost quantum mechanical and force-field methods. This study aims to establish a standard for the efficient computational prediction of IR spectra, facilitating the rapid and reliable identification of unknown compounds and advancing automated analytical workflows in chemistry.

Cross-view video geo-localization (CVGL) aims to derive GPS trajectories from street-view videos by aligning them with aerial-view images. Despite their promising performance, current CVGL methods face significant challenges. These methods use camera and odometry data, typically absent in real-world scenarios. They utilize multiple adjacent frames and various encoders for feature extraction, resulting in high computational costs. Moreover, these approaches independently predict each street-view frame's location, resulting in temporally inconsistent GPS trajectories. To address these challenges, in this work, we propose GAReT, a fully transformer-based method for CVGL that does not require camera and odometry data. We introduce GeoAdapter, a transformer-adapter module designed to efficiently aggregate image-level representations and adapt them for video inputs. Specifically, we train a transformer encoder on video frames and aerial images, then freeze the encoder to optimize the GeoAdapter module to obtain video-level representation. To address temporally inconsistent trajectories, we introduce TransRetriever, an encoder-decoder transformer model that predicts GPS locations of street-view frames by encoding top-k nearest neighbor predictions per frame and auto-regressively decoding the best neighbor based on the previous frame's predictions. Our method's effectiveness is validated through extensive experiments, demonstrating state-of-the-art performance on benchmark datasets. Our code is available at https://github.com/manupillai308/GAReT., Comment: Accepted at ECCV 2024

LLM-driven dialog systems are used in a diverse set of applications, ranging from healthcare to customer service. However, given their generalization capability, it is difficult to ensure that these chatbots stay within the boundaries of the specialized domains, potentially resulting in inaccurate information and irrelevant responses. This paper introduces an unsupervised approach for automatically inducing domain-specific dialog flows that can be used to constrain LLM-based chatbots. We introduce two variants of dialog flow based on the availability of in-domain conversation instances. Through human and automatic evaluation over various dialog domains, we demonstrate that our high-quality data-guided dialog flows achieve better domain coverage, thereby overcoming the need for extensive manual crafting of such flows., Comment: Accepted at SIGDIAL 2024

Industry 4.0 has witnessed the rise of complex robots fueled by the integration of Artificial Intelligence/Machine Learning (AI/ML) and Digital Twin (DT) technologies. While these technologies offer numerous benefits, they also introduce potential privacy and security risks. This paper surveys privacy attacks targeting robots enabled by AI and DT models. Exfiltration and data leakage of ML models are discussed in addition to the potential extraction of models derived from first-principles (e.g., physics-based). We also discuss design considerations with DT-integrated robotics touching on the impact of ML model training, responsible AI and DT safeguards, data governance and ethical considerations on the effectiveness of these attacks. We advocate for a trusted autonomy approach, emphasizing the need to combine robotics, AI, and DT technologies with robust ethical frameworks and trustworthiness principles for secure and reliable AI robotic systems., Comment: 10 pages, 3 figures, 1 table

The advancement of large language models (LLMs) has demonstrated strong capabilities across various applications, including mental health analysis. However, existing studies have focused on predictive performance, leaving the critical issue of fairness underexplored, posing significant risks to vulnerable populations. Despite acknowledging potential biases, previous works have lacked thorough investigations into these biases and their impacts. To address this gap, we systematically evaluate biases across seven social factors (e.g., gender, age, religion) using ten LLMs with different prompting methods on eight diverse mental health datasets. Our results show that GPT-4 achieves the best overall balance in performance and fairness among LLMs, although it still lags behind domain-specific models like MentalRoBERTa in some cases. Additionally, our tailored fairness-aware prompts can effectively mitigate bias in mental health predictions, highlighting the great potential for fair analysis in this field., Comment: In submission; Data and code are available at: https://github.com/EternityYW/BiasEval-LLM-MentalHealth

Plasmon resonance in metals represents the collective oscillation of the free electron gas density and enables enhanced light-matter interactions in nanoscale dimensions. Traditionally, the classical Drude model describes the plasmonic excitation, wherein the plasma frequency exhibits no spatial dispersion. Here, we show conclusive experimental evidence of the breakdown of the plasmon resonance and a consequent photonic metal-insulator transition in an ultrathin archetypal refractory plasmonic material, hafnium nitride (HfN). Epitaxial HfN thick films exhibit a low-loss and high-quality Drude-like plasmon resonance in the visible spectral range. However, as the film thickness is reduced to nanoscale dimensions, the Coulomb interaction among electrons increases due to the electron confinement, leading to the spatial dispersion of the plasma frequency. Importantly, with the further decrease in thickness, electrons lose their ability to shield the incident electric field, turning the medium into a dielectric. The breakdown of the plasmon resonance in epitaxial ultrathin metals could be useful for fundamental physics studies in transdimensional regimes and novel photonic device applications.

This paper introduces Ethics Pathways, a design activity aimed at understanding HCI and design researchers' ethics engagements and flows during their research process. Despite a strong ethical commitment in these fields, challenges persist in grasping the complexity of researchers' engagement with ethics -- practices conducted to operationalize ethics -- in situated institutional contexts. Ethics Pathways, developed through six playtesting sessions, offers a design approach to understanding the complexities of researchers' past ethics engagements in their work. This activity involves four main tasks: recalling ethical incidents; describing stakeholders involved in the situation; recounting their actions or speculative alternatives; and reflection and emotion walk-through. The paper reflects on the role of design decisions and facilitation strategies in achieving these goals. The design activity contributes to the discourse on ethical HCI research by conceptualizing ethics engagement as a part of ongoing research processing, highlighting connections between individual affective experiences, social interactions across power differences, and institutional goals., Comment: Accepted at ACM Designing Interactive Systems (DIS) 2024

Synthetic microbiomes offer new possibilities for modulating microbiota, to address the barriers in multidtug resistance (MDR) research. We present a Bayesian optimization approach to enable efficient searching over the space of synthetic microbiome variants to identify candidates predictive of reduced MDR. Microbiome datasets were encoded into a low-dimensional latent space using autoencoders. Sampling from this space allowed generation of synthetic microbiome signatures. Bayesian optimization was then implemented to select variants for biological screening to maximize identification of designs with restricted MDR pathogens based on minimal samples. Four acquisition functions were evaluated: expected improvement, upper confidence bound, Thompson sampling, and probability of improvement. Based on each strategy, synthetic samples were prioritized according to their MDR detection. Expected improvement, upper confidence bound, and probability of improvement consistently produced synthetic microbiome candidates with significantly fewer searches than Thompson sampling. By combining deep latent space mapping and Bayesian learning for efficient guided screening, this study demonstrated the feasibility of creating bespoke synthetic microbiomes with customized MDR profiles.

Interactions among biologically active agents is facilitated by their self-generated chemical and hydrodynamic fields. In order to elucidate the pair-wise interactions between such micro-organisms, we employ active droplets as a model system, capable of self-generating chemical and hydrodynamic fields. We demonstrate that the solute P\'eclet number ($Pe$), characterizing the relative strength of its convective to diffusive transport, plays a crucial role in determining how the chemical and hydrodynamic fields impact their interactions. Our findings reveal that at low $Pe$, the interaction is predominantly governed by chemo-repulsive effects, leading to droplets avoiding physical contact. Conversely, at elevated $Pe$, hydrodynamic interactions become more influential, leading to physical engagement. However, irrespective of $Pe$, the interaction of a droplet with the chemical trail of another droplet is always governed by chemo-repulsive effects. Furthermore, our results establish that the chemo-repulsive deflection/rebounding of droplets is influenced by the droplets' inherent chemical polarity, as determined by its $Pe$, independent of their approach orientation. Our findings offer a methodology for tuning the outcomes of binary interactions among chemically active droplets, laying the groundwork for potential studies on their collective dynamics., Comment: 11 pages, 6 figures

A compact source, G0.02467-0.0727, was detected in ALMA \threemm observations in continuum and very broad line emission. The continuum emission has a spectral index $\alpha\approx3.3$, suggesting that the emission is from dust. The line emission is detected in several transitions of CS, SO, and SO$_2$ and exhibits a line width FWHM $\approx160$ \kms. The line profile appears Gaussian. The emission is weakly spatially resolved, coming from an area on the sky $\lesssim1"$ in diameter ($\lesssim10^4$ AU at the distance of the Galactic Center; GC). The centroid velocity is $v_{LSR}\approx40$-$50$ \kms, which is consistent with a location in the Galactic Center. With multiple SO lines detected, and assuming local thermodynamic equilibrium (LTE) conditions, $T_\mathrm{LTE} = 13$ K, which is colder than seen in typical GC clouds, though we cannot rule out low-density, subthermally excited, warmer gas. Despite the high velocity dispersion, no emission is observed from SiO, suggesting that there are no strong ($\gtrsim10~\mathrm{km~s}^{-1}$) shocks in the molecular gas. There are no detections at other wavelengths, including X-ray, infrared, and radio. We consider several explanations for the Millimeter Ultra-Broad Line Object (MUBLO), including protostellar outflow, explosive outflow, collapsing cloud, evolved star, stellar merger, high-velocity compact cloud, intermediate mass black hole, and background galaxy. Most of these conceptual models are either inconsistent with the data or do not fully explain it. The MUBLO is, at present, an observationally unique object., Comment: Accepted to ApJL

Given the widespread use of safety-critical applications in the automotive field, it is crucial to ensure the Functional Safety (FuSa) of circuits and components within automotive systems. The Analog and Mixed-Signal (AMS) circuits prevalent in these systems are more vulnerable to faults induced by parametric perturbations, noise, environmental stress, and other factors, in comparison to their digital counterparts. However, their continuous signal characteristics present an opportunity for early anomaly detection, enabling the implementation of safety mechanisms to prevent system failure. To address this need, we propose a novel framework based on unsupervised machine learning for early anomaly detection in AMS circuits. The proposed approach involves injecting anomalies at various circuit locations and individual components to create a diverse and comprehensive anomaly dataset, followed by the extraction of features from the observed circuit signals. Subsequently, we employ clustering algorithms to facilitate anomaly detection. Finally, we propose a time series framework to enhance and expedite anomaly detection performance. Our approach encompasses a systematic analysis of anomaly abstraction at multiple levels pertaining to the automotive domain, from hardware- to block-level, where anomalies are injected to create diverse fault scenarios. By monitoring the system behavior under these anomalous conditions, we capture the propagation of anomalies and their effects at different abstraction levels, thereby potentially paving the way for the implementation of reliable safety mechanisms to ensure the FuSa of automotive SoCs. Our experimental findings indicate that our approach achieves 100% anomaly detection accuracy and significantly optimizes the associated latency by 5X, underscoring the effectiveness of our devised solution., Comment: 12 pages, 12 figures

MindScape aims to study the benefits of integrating time series behavioral patterns (e.g., conversational engagement, sleep, location) with Large Language Models (LLMs) to create a new form of contextual AI journaling, promoting self-reflection and well-being. We argue that integrating behavioral sensing in LLMs will likely lead to a new frontier in AI. In this Late-Breaking Work paper, we discuss the MindScape contextual journal App design that uses LLMs and behavioral sensing to generate contextual and personalized journaling prompts crafted to encourage self-reflection and emotional development. We also discuss the MindScape study of college students based on a preliminary user study and our upcoming study to assess the effectiveness of contextual AI journaling in promoting better well-being on college campuses. MindScape represents a new application class that embeds behavioral intelligence in AI.

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to understand and use computing languages. An open-source, user-friendly interface for AI models, that does not require programming skills to analyze complex biological data will be extremely valuable to the bioinformatics community. With easy access to different sequencing technologies and increased interest in different 'omics' studies, the number of biological datasets being generated has increased and analyzing these high-throughput datasets is computationally demanding. The majority of AI libraries today require advanced programming skills as well as machine learning, data preprocessing, and visualization skills. In this research, we propose a web-based end-to-end pipeline that is capable of preprocessing, training, evaluating, and visualizing machine learning (ML) models without manual intervention or coding expertise. By integrating traditional machine learning and deep neural network models with visualizations, our library assists in recognizing, classifying, clustering, and predicting a wide range of multi-modal, multi-sensor datasets, including images, languages, and one-dimensional numerical data, for drug discovery, pathogen classification, and medical diagnostics., Comment: 2024 7th International Conference on Information and Computer Technologies (ICICT)

In voltage imaging, where the membrane potentials of individual neurons are recorded at from hundreds to thousand frames per second using fluorescence microscopy, data processing presents a challenge. Even a fraction of a minute of recording with a limited image size yields gigabytes of video data consisting of tens of thousands of frames, which can be time-consuming to process. Moreover, millisecond-level short exposures lead to noisy video frames, obscuring neuron footprints especially in deep-brain samples where noisy signals are buried in background fluorescence. To address this challenge, we propose a fast neuron segmentation method able to detect multiple, potentially overlapping, spiking neurons from noisy video frames, and implement a data processing pipeline incorporating the proposed segmentation method along with GPU-accelerated motion correction. By testing on existing datasets as well as on new datasets we introduce, we show that our pipeline extracts neuron footprints that agree well with human annotation even from cluttered datasets, and demonstrate real-time processing of voltage imaging data on a single desktop computer for the first time.

The interstellar medium in the Milky Way's Central Molecular Zone (CMZ) is known to be strongly magnetised, but its large-scale morphology and impact on the gas dynamics are not well understood. We explore the impact and properties of magnetic fields in the CMZ using three-dimensional non-self gravitating magnetohydrodynamical simulations of gas flow in an external Milky Way barred potential. We find that: (1) The magnetic field is conveniently decomposed into a regular time-averaged component and an irregular turbulent component. The regular component aligns well with the velocity vectors of the gas everywhere, including within the bar lanes. (2) The field geometry transitions from parallel to the Galactic plane near $z=0$ to poloidal away from the plane. (3) The magneto-rotational instability (MRI) causes an in-plane inflow of matter from the CMZ gas ring towards the central few parsecs of $0.01-0.1$ M$_\odot$ yr$^{-1}$ that is absent in the unmagnetised simulations. However, the magnetic fields have no significant effect on the larger-scale bar-driven inflow that brings the gas from the Galactic disc into the CMZ. (4) A combination of bar inflow and MRI-driven turbulence can sustain a turbulent vertical velocity dispersion of $\sigma_z \simeq 5$ km s$^{-1}$ on scales of $20$ pc in the CMZ ring. The MRI alone sustains a velocity dispersion of $\sigma_z \simeq 3$ km s$^{-1}$. Both these numbers are lower than the observed velocity dispersion of gas in the CMZ, suggesting that other processes such as stellar feedback are necessary to explain the observations. (5) Dynamo action driven by differential rotation and the MRI amplifies the magnetic fields in the CMZ ring until they saturate at a value that scales with the average local density as $B \simeq 102 (n/10^3 cm^{-3})^{0.33}$ $\mu$G. Finally, we discuss the implications of our results within the observational context in the CMZ.

Piezoelectric micro-electro-mechanical systems have significant market potential owing to their superior capabilities of transduction to those of standard capacitive and piezoresistive devices. However, piezoelectric films are often lossy, which reduces the quality factor of devices and affects their performance. It is thus important to examine all sources of energy losses in such devices and accurately determine them based on experimental data. Currently used methods to quantify energy loss from different sources and the properties of materials based on experimental data are set-up for piezoelectric devices, in which energy storage and loss primarily occur in the same piezoelectric material. Moreover, such methods rely on resonance-antiresonance measurements, and thus are unsuitable for thin-film-piezoelectric-on substrate (TPoS) micro/nano devices that have i) a significant portion of energy stored in the substrate/device layer, ii) a low signal-to-noise ratio owing to either lossy piezoelectric films or low motional impedance, or iii) a larger feedthrough capacitance in addition to the internal capacitance of the piezoelectric film. In this paper, we propose a method that overcomes these challenges based on synchronized optical and electrical measurements. We develop a comprehensive physics-based model to extract all the relevant parameters for the device, including the coefficient of piezoelectric coupling, internal and feedthrough capacitance, loss tangents (dielectric, piezoelectric, and mechanical), and the contributions of different sources to the quality factor of the device. We showcase the proposed method by using a PZT-based TPoS MEMS cantilever. It can be universally applied to all piezoelectric materials and arbitrary stacks of the device layer., Comment: 24 pages, 9 figures

In this report, we introduce the Gemini 1.5 family of models, representing the next generation of highly compute-efficient multimodal models capable of recalling and reasoning over fine-grained information from millions of tokens of context, including multiple long documents and hours of video and audio. The family includes two new models: (1) an updated Gemini 1.5 Pro, which exceeds the February version on the great majority of capabilities and benchmarks; (2) Gemini 1.5 Flash, a more lightweight variant designed for efficiency with minimal regression in quality. Gemini 1.5 models achieve near-perfect recall on long-context retrieval tasks across modalities, improve the state-of-the-art in long-document QA, long-video QA and long-context ASR, and match or surpass Gemini 1.0 Ultra's state-of-the-art performance across a broad set of benchmarks. Studying the limits of Gemini 1.5's long-context ability, we find continued improvement in next-token prediction and near-perfect retrieval (>99%) up to at least 10M tokens, a generational leap over existing models such as Claude 3.0 (200k) and GPT-4 Turbo (128k). Finally, we highlight real-world use cases, such as Gemini 1.5 collaborating with professionals on completing their tasks achieving 26 to 75% time savings across 10 different job categories, as well as surprising new capabilities of large language models at the frontier; when given a grammar manual for Kalamang, a language with fewer than 200 speakers worldwide, the model learns to translate English to Kalamang at a similar level to a person who learned from the same content.

We have comprehensively studied the multi-scale physical properties of the infrared dark cloud (IRDC) G28.34 (the Dragon cloud) with dust polarization and molecular line data from Planck, FCRAO-14m, JCMT, and ALMA. We find that the averaged magnetic fields of clumps tend to be either parallel with or perpendicular to the cloud-scale magnetic fields, while the cores in clump MM4 tend to have magnetic fields aligned with the clump fields. Implementing the relative orientation analysis (for magnetic fields, column density gradients, and local gravity), Velocity Gradient Technique (VGT), and modified Davis-Chandrasekhar-Fermi (DCF) analysis, we find that: G28.34 is located in a trans-to-sub-Alfv\'{e}nic environment ($\mathcal{M}_{A}=0.74$ within $r=15$ pc); the magnetic field is effectively resisting gravitational collapse in large-scale diffuse gas, but is distorted by gravity within the cloud and affected by star formation activities in high-density regions; and the normalized mass-to-flux ratio tends to increase with increasing density and decreasing radius. Considering the thermal, turbulent, and magnetic supports, we find that the environmental gas of G28.34 is in a super-virial (supported) state, the infrared dark clumps may be in a near-equilibrium state, and core MM4-core4 is in a sub-virial (gravity-dominant) state. In summary, we suggest that magnetic fields dominate gravity and turbulence in the cloud environment at large scales, resulting in relatively slow cloud formation and evolution processes. Within the cloud, gravity could overwhelm magnetic fields and turbulence, allowing local dynamical star formation to happen., Comment: 35 pages, 24 figures. Accepted by ApJ