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Your search keyword '"Pilli, Nageswara R."' showing total 9 results
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9 results on '"Pilli, Nageswara R."'

5. Effects of sedative psychotropic drugs combined with oxycodone on respiratory depression in the rat

Author

Xu, Lin, primary, Krishna, Ashok, additional, Stewart, Sharron, additional, Shea, Katherine, additional, Racz, Rebecca, additional, Weaver, James L., additional, Volpe, Donna A., additional, Pilli, Nageswara R., additional, Narayanasamy, Suresh, additional, Florian, Jeffry, additional, Patel, Vikram, additional, Matta, Murali K., additional, Stone, Marc B., additional, Zhu, Hao, additional, Davis, Michael C., additional, Strauss, David G., additional, and Rouse, Rodney, additional

Published
2021
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6. Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients

Author

Matta, Murali K., primary, Florian, Jeffry, additional, Zusterzeel, Robbert, additional, Pilli, Nageswara R., additional, Patel, Vikram, additional, Volpe, Donna A., additional, Yang, Yang, additional, Oh, Luke, additional, Bashaw, Edward, additional, Zineh, Issam, additional, Sanabria, Carlos, additional, Kemp, Sarah, additional, Godfrey, Anthony, additional, Adah, Steven, additional, Coelho, Sergio, additional, Wang, Jian, additional, Furlong, Lesley-Anne, additional, Ganley, Charles, additional, Michele, Theresa, additional, and Strauss, David G., additional

Published
2020
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8. Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients

Author

Matta, Murali K., primary, Zusterzeel, Robbert, additional, Pilli, Nageswara R., additional, Patel, Vikram, additional, Volpe, Donna A., additional, Florian, Jeffry, additional, Oh, Luke, additional, Bashaw, Edward, additional, Zineh, Issam, additional, Sanabria, Carlos, additional, Kemp, Sarah, additional, Godfrey, Anthony, additional, Adah, Steven, additional, Coelho, Sergio, additional, Wang, Jian, additional, Furlong, Lesley-Anne, additional, Ganley, Charles, additional, Michele, Theresa, additional, and Strauss, David G., additional

Published
2019
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9. Prebiotic Treatment in People With Schizophrenia.

Author

Buchanan RW, Werkheiser AE, Michel H, Zaranski J, Glassman M, Adams HA, Vyas G, Blatt F, Pilli NR, Pan Y, Chen S, Fraser CM, Kelly DL, and Kane MA

Abstract

Background: Preliminary evidence suggests that people with schizophrenia have decreased relative abundance of butyrate-producing bacteria in the gut microbiota. Butyrate plays a critical role in maintaining the integrity of the gut-blood barrier and has a number of anti-inflammatory effects. This proof-of-concept study was designed to assess whether the addition of the oligofructose-enriched inulin (OEI) prebiotic: Prebiotin could increase the production of butyrate., Methods: Twenty-seven people who met the criteria for either Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, schizophrenia or schizoaffective disorder were entered into a 10-day, double-blind, placebo-controlled, randomized clinical trial. The study was conducted on an inpatient unit to standardize the participant diet and environment. Participants were randomized to either OEI (4 g, 3 times a day) or a placebo (4 g of maltodextrin, 3 times a day). In order to assess the effect of OEI treatment on butyrate levels, participants underwent pretreatment and posttreatment OEI challenges. The primary outcome measure was relative change in postchallenge plasma butyrate levels after 10 days of OEI treatment., Results: In both the intent-to-treat and completer analyses, OEI treatment was associated with a greater number of participants who met the OEI challenge responder criteria than those treated with placebo. OEI treatment was also associated with an increase in baseline butyrate levels (effect size for the group difference in the change of baseline butyrate levels was 0.58)., Conclusions: We were able to demonstrate that treatment with the prebiotic OEI selectively increased the level of plasma butyrate in people with schizophrenia.Trial registration:ClinicalTrials.gov identifier NCT03617783., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2024
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